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Conserved domains on  [gi|1842034347|ref|YP_009821268|]
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putative HD domain protein [Erwinia phage Derbicus]

Protein Classification

HD domain-containing protein( domain architecture ID 707124)

HD domain-containing protein may function as a metal dependent phosphohydrolase; similar to Bacillus subtilis phosphohydrolase YueE

CATH:  3.30.70.1370|1.20.58.1910
EC:  3.1.-.-
Gene Ontology:  GO:0046872|GO:0016787
PubMed:  9868367
SCOP:  4000705

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RnaY super family cl28470
HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal ...
 13-128 5.14e-04

HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal structure and biogenesis, General function prediction only];


The actual alignment was detected with superfamily member COG1418:

Pssm-ID: 441028 [Multi-domain]  Cd Length: 191  Bit Score: 39.50  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842034347  13 AEYYQHTDPAHRIDHIVKTMNNAEILFDKLNLRHDkalmkkVLIAIGY-HDV-WSQNRKYHHVDAYLEVcKHTRRIQEHY 90
Cdd:COG1418     8 VKYLRTSYGQHDLQHSLRVAKLAGLIAAEEGADVE------VAKRAALlHDIgKAKDHEVEGSHAEIGA-ELARKYLESL 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1842034347  91 GISQEDVWRIAHACLEHRASFKGKYDSIISEITAAADR 128
Cdd:COG1418    81 GFPEEEIEAVVHAIEAHSFSGGIEPESLEAKIVQDADR 118
 
Name Accession Description Interval E-value
RnaY COG1418
HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal ...
 13-128 5.14e-04

HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal structure and biogenesis, General function prediction only];


Pssm-ID: 441028 [Multi-domain]  Cd Length: 191  Bit Score: 39.50  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842034347  13 AEYYQHTDPAHRIDHIVKTMNNAEILFDKLNLRHDkalmkkVLIAIGY-HDV-WSQNRKYHHVDAYLEVcKHTRRIQEHY 90
Cdd:COG1418     8 VKYLRTSYGQHDLQHSLRVAKLAGLIAAEEGADVE------VAKRAALlHDIgKAKDHEVEGSHAEIGA-ELARKYLESL 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1842034347  91 GISQEDVWRIAHACLEHRASFKGKYDSIISEITAAADR 128
Cdd:COG1418    81 GFPEEEIEAVVHAIEAHSFSGGIEPESLEAKIVQDADR 118
 
Name Accession Description Interval E-value
RnaY COG1418
HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal ...
 13-128 5.14e-04

HD superfamily phosphodieaserase, includes HD domain of RNase Y [Translation, ribosomal structure and biogenesis, General function prediction only];


Pssm-ID: 441028 [Multi-domain]  Cd Length: 191  Bit Score: 39.50  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842034347  13 AEYYQHTDPAHRIDHIVKTMNNAEILFDKLNLRHDkalmkkVLIAIGY-HDV-WSQNRKYHHVDAYLEVcKHTRRIQEHY 90
Cdd:COG1418     8 VKYLRTSYGQHDLQHSLRVAKLAGLIAAEEGADVE------VAKRAALlHDIgKAKDHEVEGSHAEIGA-ELARKYLESL 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1842034347  91 GISQEDVWRIAHACLEHRASFKGKYDSIISEITAAADR 128
Cdd:COG1418    81 GFPEEEIEAVVHAIEAHSFSGGIEPESLEAKIVQDADR 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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