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Conserved domains on  [gi|1842033255|ref|YP_009820158|]
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HNH endonuclease [Escherichia phage NC-A]

Protein Classification

HNH endonuclease signature motif containing protein( domain architecture ID 10598305)

HNH endonuclease signature motif containing protein which may catalyze the hydrolysis of DNA

EC:  3.1.-.-
Gene Ontology:  GO:0004519

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HNH_3 pfam13392
HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in ...
 50-94 2.89e-18

HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.


:

Pssm-ID: 433169  Cd Length: 46  Bit Score: 73.01  E-value: 2.89e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1842033255  50 VQVHRIVWVLNFGSIPAGMEIDHINRNPSDNRIENLRLVTRSQNG 94
Cdd:pfam13392   1 KYAHRVAWELHNGPIPDGMVVDHIDGDRRNNRPENLRLVTRRENA 45
 
Name Accession Description Interval E-value
HNH_3 pfam13392
HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in ...
 50-94 2.89e-18

HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.


Pssm-ID: 433169  Cd Length: 46  Bit Score: 73.01  E-value: 2.89e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1842033255  50 VQVHRIVWVLNFGSIPAGMEIDHINRNPSDNRIENLRLVTRSQNG 94
Cdd:pfam13392   1 KYAHRVAWELHNGPIPDGMVVDHIDGDRRNNRPENLRLVTRRENA 45
PHA00280 PHA00280
putative NHN endonuclease
 51-133 3.01e-13

putative NHN endonuclease


Pssm-ID: 106901 [Multi-domain]  Cd Length: 121  Bit Score: 62.11  E-value: 3.01e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842033255  51 QVHRIVWVLNFGSIPAGMEIDHINRNPSDNRIENLRLVTRSQNGFNRRVPKQSRTGERYIHTCSKTGRF--IVRISGKSY 128
Cdd:PHA00280   13 RRHIQVWEAANGPIPKGYYIDHIDGNPLNDALDNLRLALPKENSWNMKTPKSNTSGLKGLSWSKEREMWrgTVTAEGKQH 92


                  ....*
gi 1842033255 129 GTYGT 133
Cdd:PHA00280   93 NFRSR 97
 
Name Accession Description Interval E-value
HNH_3 pfam13392
HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in ...
 50-94 2.89e-18

HNH endonuclease; This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.


Pssm-ID: 433169  Cd Length: 46  Bit Score: 73.01  E-value: 2.89e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1842033255  50 VQVHRIVWVLNFGSIPAGMEIDHINRNPSDNRIENLRLVTRSQNG 94
Cdd:pfam13392   1 KYAHRVAWELHNGPIPDGMVVDHIDGDRRNNRPENLRLVTRRENA 45
PHA00280 PHA00280
putative NHN endonuclease
 51-133 3.01e-13

putative NHN endonuclease


Pssm-ID: 106901 [Multi-domain]  Cd Length: 121  Bit Score: 62.11  E-value: 3.01e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1842033255  51 QVHRIVWVLNFGSIPAGMEIDHINRNPSDNRIENLRLVTRSQNGFNRRVPKQSRTGERYIHTCSKTGRF--IVRISGKSY 128
Cdd:PHA00280   13 RRHIQVWEAANGPIPKGYYIDHIDGNPLNDALDNLRLALPKENSWNMKTPKSNTSGLKGLSWSKEREMWrgTVTAEGKQH 92


                  ....*
gi 1842033255 129 GTYGT 133
Cdd:PHA00280   93 NFRSR 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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