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Conserved domains on  [gi|1839555803|ref|XP_034115699|]
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anaphase-promoting complex subunit 7 [Drosophila albomicans]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-506 6.19e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 90.17  E-value: 6.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 242 GKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGkkNVEQ-----ETLIAPIRTRSTGefksphWFLLAQLA 316
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG--EYDRairihQKLLERDPDRAEA------LLELAQDY 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 317 YANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNM 396
Cdd:COG2956    87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 397 CALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP 476
Cdd:COG2956   167 LEKALKLDPDCARALLLLAELYLEQGDYE---EAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243

                         250       260       270
                  ....*....|....*....|....*....|
gi 1839555803 477 HPKLFAMLAELLSSEKDLDGALHFYMKALR 506
Cdd:COG2956   244 SDDLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 97-392 2.98e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 2.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803  97 QDAELRYRIAKCYREMGDDQMAISVLQATKSRTPK---LNMLMAKLQLHHARYltktQKA-AAYKDVLRDCPMSLTAIEA 172
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDraeALLELAQDYLKAGLL----DRAeELLEKLLELDPDDAEALRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 173 LIELGIEGSEvhsmvvnasnmskhiewlssWIKAhaqmygckhLEAAKTFQQLNEttllrQNHHLLTNIGKCLYYYGNFI 252
Cdd:COG2956   116 LAEIYEQEGD--------------------WEKA---------IEVLERLLKLGP-----ENAHAYCELAELYLEQGDYD 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 253 QAELYLETAARNNTYNMNAigllavvyeyngkknveqetliapirtrstgefksphWFLLAQLAYANSKYERALIYTDRA 332
Cdd:COG2956   162 EAIEALEKALKLDPDCARA-------------------------------------LLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 333 LDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKgLLACYIRQKRMKE 392
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEA 263
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-506 6.19e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 90.17  E-value: 6.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 242 GKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGkkNVEQ-----ETLIAPIRTRSTGefksphWFLLAQLA 316
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG--EYDRairihQKLLERDPDRAEA------LLELAQDY 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 317 YANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNM 396
Cdd:COG2956    87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 397 CALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP 476
Cdd:COG2956   167 LEKALKLDPDCARALLLLAELYLEQGDYE---EAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243

                         250       260       270
                  ....*....|....*....|....*....|
gi 1839555803 477 HPKLFAMLAELLSSEKDLDGALHFYMKALR 506
Cdd:COG2956   244 SDDLLLALADLLERKEGLEAALALLERQLR 273
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 114-510 1.92e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 70.88  E-value: 1.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 114 DDQMAIS--VLQATKSRTPKLNmlmakLQLHHARYLTKTQKA-AAYKDVLR---DCPMSLTA-IEALIELG-IEGSEVH- 184
Cdd:TIGR02917 176 DEARALIdeVLTADPGNVDALL-----LKGDLLLSLGNIELAlAAYRKAIAlrpNNIAVLLAlATILIEAGeFEEAEKHa 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 185 -SMVVNASNMSKhiewlSSWIKAHAQMYGCKHLEAAKTFQqlnetTLLRQNHHLLTNI---GKCLYYYGNFIQAELYLET 260
Cdd:TIGR02917 251 dALLKKAPNSPL-----AHYLKALVDFQKKNYEDARETLQ-----DALKSAPEYLPALllaGASEYQLGNLEQAYQYLNQ 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 261 AARNNTYNMNAIGLLAVVYEYNGKKNVEQETLIAPIRTRSTgefkSPHWFLLAQLAY-ANSKYERALIYTDRALDIDPRN 339
Cdd:TIGR02917 321 ILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPD----DPAALSLLGEAYlALGDFEKAAEYLAKATELDPEN 396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 340 MEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKEshnmcALAV-----RYFSTSPRSYTMF 414
Cdd:TIGR02917 397 AAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDK-----ALAAakkleKKQPDNASLHNLL 471

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 415 GHTLFhssNPQVKKSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP-HPKLFAMLAELLSSEKD 493
Cdd:TIGR02917 472 GAIYL---GKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPkNLRAILALAGLYLRTGN 548

                         410
                  ....*....|....*..
gi 1839555803 494 LDGALHFYMKALRMEPT 510
Cdd:TIGR02917 549 EEEAVAWLEKAAELNPQ 565
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 97-392 2.98e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 2.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803  97 QDAELRYRIAKCYREMGDDQMAISVLQATKSRTPK---LNMLMAKLQLHHARYltktQKA-AAYKDVLRDCPMSLTAIEA 172
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDraeALLELAQDYLKAGLL----DRAeELLEKLLELDPDDAEALRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 173 LIELGIEGSEvhsmvvnasnmskhiewlssWIKAhaqmygckhLEAAKTFQQLNEttllrQNHHLLTNIGKCLYYYGNFI 252
Cdd:COG2956   116 LAEIYEQEGD--------------------WEKA---------IEVLERLLKLGP-----ENAHAYCELAELYLEQGDYD 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 253 QAELYLETAARNNTYNMNAigllavvyeyngkknveqetliapirtrstgefksphWFLLAQLAYANSKYERALIYTDRA 332
Cdd:COG2956   162 EAIEALEKALKLDPDCARA-------------------------------------LLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 333 LDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKgLLACYIRQKRMKE 392
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEA 263
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 312-521 1.00e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.19  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 312 LAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGP-YRFEIYKGLLACYirqkrm 390
Cdd:PRK11788  186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPeYLSEVLPKLMECY------ 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 391 keshnmcalavryfstsprsytmfghtlfhssnpqvkksakkfvekalqidehyapgialmagifQHEGAAQEAIGLLRK 470
Cdd:PRK11788  260 -----------------------------------------------------------------QALGDEAEGLEFLRR 274

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1839555803 471 QVTNYPHPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTfrraLDGFDAL 521
Cdd:PRK11788  275 ALEEYPGADLLLALAQLLEEQEGPEAAQALLREQLRRHPS----LRGFHRL 321
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 310-372 1.26e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.40  E-value: 1.26e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839555803 310 FLLAQLAYANSKYERALIYTDRALDID---PRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPY 372
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
Fis1 cd12212
Mitochondrial Fission Protein Fis1, cytosolic domain; Fis1, along with Dnm1 and Mdv1, is an ...
 310-346 2.60e-03

Mitochondrial Fission Protein Fis1, cytosolic domain; Fis1, along with Dnm1 and Mdv1, is an essential protein in mediating mitochondrial fission. Dnm1 and Fis1 are highly conserved, with a common mechanism in disparate species. In mutants of these proteins, mitochondrial fission is impaired, resulting in networks of undivided mitochondria. The Fis1 N-terminus is cytosolic and tethered to the mitochondrial outer membrane via a C-terminal transmembrane domain. Fis1 appears to act via the recruitment of division complexes to the mitochondrial outer membrane, via interactions with Mdv1 or Caf4. Fis1 has tandem Tetratricopeptide repeat (TPR) motifs which are known to mediate protein-protein interactions.


Pssm-ID: 276936 [Multi-domain]  Cd Length: 115  Bit Score: 38.30  E-value: 2.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1839555803 310 FLLAqLAYANSK-YERALIYTDRALDIDPRNMEALLLR 346
Cdd:cd12212    67 YYLA-LGHYKLGeYSEARRYVDALLEIEPDNRQALALK 103
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 242-506 6.19e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 90.17  E-value: 6.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 242 GKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGkkNVEQ-----ETLIAPIRTRSTGefksphWFLLAQLA 316
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG--EYDRairihQKLLERDPDRAEA------LLELAQDY 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 317 YANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNM 396
Cdd:COG2956    87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 397 CALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP 476
Cdd:COG2956   167 LEKALKLDPDCARALLLLAELYLEQGDYE---EAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243

                         250       260       270
                  ....*....|....*....|....*....|
gi 1839555803 477 HPKLFAMLAELLSSEKDLDGALHFYMKALR 506
Cdd:COG2956   244 SDDLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 309-509 7.18e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.40  E-value: 7.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQK 388
Cdd:COG2956    45 HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 389 RMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPqvkKSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLL 468
Cdd:COG2956   125 DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDY---DEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAAL 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1839555803 469 RKQVTNYP-HPKLFAMLAELLSSEKDLDGALHFYMKALRMEP 509
Cdd:COG2956   202 ERALEQDPdYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 309-516 1.24e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 83.63  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQK 388
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 389 RMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLL 468
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWE---KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEAL 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1839555803 469 RKQVTNYP-HPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTFRRALD 516
Cdd:COG2956   168 EKALKLDPdCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
309-521 3.75e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 3.75e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQK 388
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 389 RMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLL 468
Cdd:COG0457    91 RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYD---EAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1839555803 469 RKQVTNYPHPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTFRRALDGFDAL 521
Cdd:COG0457   168 EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALA 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 114-510 1.92e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 70.88  E-value: 1.92e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 114 DDQMAIS--VLQATKSRTPKLNmlmakLQLHHARYLTKTQKA-AAYKDVLR---DCPMSLTA-IEALIELG-IEGSEVH- 184
Cdd:TIGR02917 176 DEARALIdeVLTADPGNVDALL-----LKGDLLLSLGNIELAlAAYRKAIAlrpNNIAVLLAlATILIEAGeFEEAEKHa 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 185 -SMVVNASNMSKhiewlSSWIKAHAQMYGCKHLEAAKTFQqlnetTLLRQNHHLLTNI---GKCLYYYGNFIQAELYLET 260
Cdd:TIGR02917 251 dALLKKAPNSPL-----AHYLKALVDFQKKNYEDARETLQ-----DALKSAPEYLPALllaGASEYQLGNLEQAYQYLNQ 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 261 AARNNTYNMNAIGLLAVVYEYNGKKNVEQETLIAPIRTRSTgefkSPHWFLLAQLAY-ANSKYERALIYTDRALDIDPRN 339
Cdd:TIGR02917 321 ILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPD----DPAALSLLGEAYlALGDFEKAAEYLAKATELDPEN 396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 340 MEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKEshnmcALAV-----RYFSTSPRSYTMF 414
Cdd:TIGR02917 397 AAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDK-----ALAAakkleKKQPDNASLHNLL 471

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 415 GHTLFhssNPQVKKSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP-HPKLFAMLAELLSSEKD 493
Cdd:TIGR02917 472 GAIYL---GKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPkNLRAILALAGLYLRTGN 548

                         410
                  ....*....|....*..
gi 1839555803 494 LDGALHFYMKALRMEPT 510
Cdd:TIGR02917 549 EEEAVAWLEKAAELNPQ 565
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 309-441 6.99e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 6.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQK 388
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1839555803 389 RMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQVkksAKKFVEKALQID 441
Cdd:COG4783    87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE---AIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
333-521 4.80e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 4.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 333 LDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNMCALAVRYFSTSPRSYT 412
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 413 MFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP-HPKLFAMLAELLSSE 491
Cdd:COG0457    81 NLGLALQALGRYE---EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPdDADALYNLGIALEKL 157

                         170       180       190
                  ....*....|....*....|....*....|
gi 1839555803 492 KDLDGALHFYMKALRMEPTFRRALDGFDAL 521
Cdd:COG0457   158 GRYEEALELLEKLEAAALAALLAAALGEAA 187
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 308-500 3.48e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 3.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 308 HWFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQ 387
Cdd:COG3914    80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 388 KRMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGL 467
Cdd:COG3914   160 GRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE---EAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1839555803 468 LRKQVTNYPHPKLFAMLAelLSSEKDLDGALHF 500
Cdd:COG3914   237 EELLAALARGPSELSPFA--LLYLPDDDPAELL 267
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 307-421 7.63e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.93  E-value: 7.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 307 PHWFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIR 386
Cdd:COG3914   113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQD 192

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1839555803 387 QKRMKESHNMCALAVRYFSTSPRSYTMFGHTLFHS 421
Cdd:COG3914   193 LGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 312-501 1.12e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.64  E-value: 1.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 312 LAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMK 391
Cdd:TIGR02917 505 LARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLK 584

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 392 ESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNpqvKKSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQ 471
Cdd:TIGR02917 585 KALAILNEAADAAPDSPEAWLMLGRAQLAAGD---LNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRA 661

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1839555803 472 VTNYPH-PKLFAMLAELLSSEKDLDGALHFY 501
Cdd:TIGR02917 662 LELKPDnTEAQIGLAQLLLAAKRTESAKKIA 692
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 311-515 1.81e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.78  E-value: 1.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 311 LLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGklfggLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRM 390
Cdd:COG3914    54 AAAAALLALAAGEAAAAAAALLLLAALLELAALLLQA-----LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 391 KEshnmcalAVRYFstsprsytmfghtlfhssnpqvkksakkfvEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRK 470
Cdd:COG3914   129 EE-------ALAAL------------------------------RRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1839555803 471 QVTNYP-HPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTFRRAL 515
Cdd:COG3914   172 ALELDPdNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 206-436 2.53e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.39  E-value: 2.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 206 AHAQMYGCKHLEAAKTFQQLNETTLLRQNHHLLTNIGkclyyygNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGKK 285
Cdd:COG3914    56 AAALLALAAGEAAAAAAALLLLAALLELAALLLQALG-------RYEEALALYRRALALNPDNAEALFNLGNLLLALGRL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 286 nveQETLIApirTRSTGEFKSPH---WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQA 362
Cdd:COG3914   129 ---EEALAA---LRRALALNPDFaeaYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAA 202

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1839555803 363 FRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQVKKSAKKFVEK 436
Cdd:COG3914   203 YRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARAWAQL 276
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 238-366 7.58e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.81  E-value: 7.58e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 238 LTNIGKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGKKNvEQETLIAPIRTRSTGEFKSphWFLLAQLAY 317
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLD-EAIVLLHEALELDPDEPEA--RLNLGLALL 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1839555803 318 ANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTA 366
Cdd:COG4783    84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 97-392 2.98e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.51  E-value: 2.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803  97 QDAELRYRIAKCYREMGDDQMAISVLQATKSRTPK---LNMLMAKLQLHHARYltktQKA-AAYKDVLRDCPMSLTAIEA 172
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDraeALLELAQDYLKAGLL----DRAeELLEKLLELDPDDAEALRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 173 LIELGIEGSEvhsmvvnasnmskhiewlssWIKAhaqmygckhLEAAKTFQQLNEttllrQNHHLLTNIGKCLYYYGNFI 252
Cdd:COG2956   116 LAEIYEQEGD--------------------WEKA---------IEVLERLLKLGP-----ENAHAYCELAELYLEQGDYD 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 253 QAELYLETAARNNTYNMNAigllavvyeyngkknveqetliapirtrstgefksphWFLLAQLAYANSKYERALIYTDRA 332
Cdd:COG2956   162 EAIEALEKALKLDPDCARA-------------------------------------LLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 333 LDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKgLLACYIRQKRMKE 392
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEA 263
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 242-526 5.97e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.25  E-value: 5.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 242 GKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGK---KNVEQETLIAPIRTRSTGEFksphwfLLAQLAYA 318
Cdd:TIGR02917 200 GDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEfeeAEKHADALLKKAPNSPLAHY------LKALVDFQ 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 319 NSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNMCA 398
Cdd:TIGR02917 274 KKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLS 353

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 399 LAVRYFSTSPRSYTMFGHTLFhsSNPQVKKSAKKF---------------------------------VEKALQIDehYA 445
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYL--ALGDFEKAAEYLakateldpenaaartqlgisklsqgdpseaiadLETAAQLD--PE 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 446 PGIALMAGIFQH--EGAAQEAIGLLRKQVTNYP-HPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTFrraldgFDALT 522
Cdd:TIGR02917 430 LGRADLLLILSYlrSGQFDKALAAAKKLEKKQPdNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDF------FPAAA 503


                  ....
gi 1839555803 523 KVAR 526
Cdd:TIGR02917 504 NLAR 507
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 312-498 6.84e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.86  E-value: 6.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 312 LAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMK 391
Cdd:TIGR02917 165 LAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFE 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 392 ESHNMCALAVRYFSTSPrsytmFGHTLfhssNPQVKKSAKKF------VEKALQIDEHYAPGIaLMAGIFQ-HEGAAQEA 464
Cdd:TIGR02917 245 EAEKHADALLKKAPNSP-----LAHYL----KALVDFQKKNYedaretLQDALKSAPEYLPAL-LLAGASEyQLGNLEQA 314

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1839555803 465 IGLLRKQVTNYPH-PKLFAMLAELLSSEKDLDGAL 498
Cdd:TIGR02917 315 YQYLNQILKYAPNsHQARRLLASIQLRLGRVDEAI 349
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 309-392 7.34e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 7.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQK 388
Cdd:COG4235    20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG 99


                  ....
gi 1839555803 389 RMKE 392
Cdd:COG4235   100 DYAE 103
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 309-371 2.57e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.00  E-value: 2.57e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGP 371
Cdd:COG4235    54 LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 156-509 7.25e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 7.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 156 YKDVLRDCPMSLTAIEALIELgiegSEVHSmvvnasNMSKHIEWLSSWIKAHAQmygckhleaaktfqqlNETTLLRQNH 235
Cdd:TIGR02917 522 FEKVLTIDPKNLRAILALAGL----YLRTG------NEEEAVAWLEKAAELNPQ----------------EIEPALALAQ 575

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 236 HLLTNigkclyyyGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGKKNVEQETLiapirtRSTGEFKSPHWFLLAQL 315
Cdd:TIGR02917 576 YYLGK--------GQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF------KKLLALQPDSALALLLL 641

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 316 AYA---NSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKE 392
Cdd:TIGR02917 642 ADAyavMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPA 721

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 393 SHNmcALAVRYfSTSPRSYTMFGHTLFHSSNPQVKKSAKKfVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQV 472
Cdd:TIGR02917 722 AIQ--AYRKAL-KRAPSSQNAIKLHRALLASGNTAEAVKT-LEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVV 797

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1839555803 473 TNYP-HPKLFAMLAELLSSEKDLDgALHFYMKALRMEP 509
Cdd:TIGR02917 798 KKAPdNAVVLNNLAWLYLELKDPR-ALEYAERALKLAP 834
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
315-402 9.02e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.47  E-value: 9.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 315 LAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQaFRTAQCLGPYRFEIYKGLLACYIRQKRMKESH 394
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                  ....*...
gi 1839555803 395 NMCALAVR 402
Cdd:COG3063    80 AYLERALE 87
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 254-392 1.82e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.42  E-value: 1.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 254 AELYLETAARNNTYNMNAIGLLAVVYEYNGKKNVEQETLIAPIRTRSTGEFKSPHWFLLAQLAYANS-KYERALIYTDRA 332
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLgDFEESLALLEQA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 333 LDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKE 392
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 331-456 2.07e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 331 RALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNMCALAVRYFSTSPRS 410
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1839555803 411 YTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQ 456
Cdd:COG4235    88 LYLLGLAAFQQGDYA---EAIAAWQKLLALLPADAPARLLEASIAE 130
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 428-509 4.61e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.72  E-value: 4.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 428 KSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP-HPKLFAMLAELLSSEKDLDGALHFYMKALR 506
Cdd:COG4783    21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPdEPEARLNLGLALLKAGDYDEALALLEKALK 100


                  ...
gi 1839555803 507 MEP 509
Cdd:COG4783   101 LDP 103
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
248-388 1.32e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 248 YGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGKKnveqetliAPIRTRSTGEFKSPH----WFLLAQLAYANSKYE 323
Cdd:COG4785    19 ASKAAILLAALLFAAVLALAIALADLALALAAAALAAA--------ALAAERIDRALALPDlaqlYYERGVAYDSLGDYD 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839555803 324 RALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGL-LACYIRQK 388
Cdd:COG4785    91 LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRgIALYYLGR 156
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
309-371 3.11e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 3.11e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1839555803 309 WFLLAQLAYANSKYERALIYtDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGP 371
Cdd:COG3063    29 LNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 321-515 4.38e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 4.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 321 KYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQ----KRMKESHNM 396
Cdd:TIGR02917  37 KYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQgkfqQVLDELPGK 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 397 CALAVRYFStspRSYTMFGHTLFHSSNPqvkKSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP 476
Cdd:TIGR02917 117 TLLDDEGAA---ELLALRGLAYLGLGQL---ELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADP 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1839555803 477 -HPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTFRRAL 515
Cdd:TIGR02917 191 gNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVL 230
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 312-521 1.00e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.19  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 312 LAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGP-YRFEIYKGLLACYirqkrm 390
Cdd:PRK11788  186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPeYLSEVLPKLMECY------ 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 391 keshnmcalavryfstsprsytmfghtlfhssnpqvkksakkfvekalqidehyapgialmagifQHEGAAQEAIGLLRK 470
Cdd:PRK11788  260 -----------------------------------------------------------------QALGDEAEGLEFLRR 274

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1839555803 471 QVTNYPHPKLFAMLAELLSSEKDLDGALHFYMKALRMEPTfrraLDGFDAL 521
Cdd:PRK11788  275 ALEEYPGADLLLALAQLLEEQEGPEAAQALLREQLRRHPS----LRGFHRL 321
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 310-372 1.26e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.40  E-value: 1.26e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839555803 310 FLLAQLAYANSKYERALIYTDRALDID---PRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPY 372
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
430-513 1.29e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 430 AKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYPHPKLFAMLAELLSSEKDLDGALHFYMKALRMEP 509
Cdd:COG3063    11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90


                  ....
gi 1839555803 510 TFRR 513
Cdd:COG3063    91 SALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 309-373 2.31e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 2.31e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYR 373
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
309-389 4.03e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYkglLACYIRQK 388
Cdd:COG4785   110 YNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERA---LWLYLAER 186


                  .
gi 1839555803 389 R 389
Cdd:COG4785   187 K 187
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 309-364 7.49e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.59  E-value: 7.49e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1839555803 309 WFLLAQLAYANSKYERALIYTDRALDIDPRN---MEALLLRGKLFGGLGRNEEAIQAFR 364
Cdd:COG1729    33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDYDKARATLE 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 311-441 8.61e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.33  E-value: 8.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 311 LLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRM 390
Cdd:COG5010    25 EKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDK 104

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1839555803 391 KESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNpqvKKSAKKFVEKALQID 441
Cdd:COG5010   105 DEAKEYYEKALALSPDNPNAYSNLAALLLSLGQ---DDEAKAALQRALGTS 152
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
301-366 1.55e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 40.64  E-value: 1.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 301 TGEFK-SPHWFL-LAQLAYANSKYERALIYTDRALDIDP--RNMEALLLRGKLFGGLGRNEEAIQAFRTA 366
Cdd:COG4700   117 TGIFAdDPHILLgLAQALFELGRYAEALETLEKLIAKNPdfKSSDAHLLYARALEALGDLEAAEAELEAL 186
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-497 2.28e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 310 FLLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLA-CYIRQK 388
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALRGlAYLGLG 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 389 RMKESHNMCALAVryfSTSPRS-YTMFGHTLFHSSNPQVKKsAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGL 467
Cdd:TIGR02917 140 QLELAQKSYEQAL---AIDPRSlYAKLGLAQLALAENRFDE-ARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAA 215

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1839555803 468 LRKQVTNYP-HPKLFAMLAELLSSEKDLDGA 497
Cdd:TIGR02917 216 YRKAIALRPnNIAVLLALATILIEAGEFEEA 246
Fis1 cd12212
Mitochondrial Fission Protein Fis1, cytosolic domain; Fis1, along with Dnm1 and Mdv1, is an ...
 310-346 2.60e-03

Mitochondrial Fission Protein Fis1, cytosolic domain; Fis1, along with Dnm1 and Mdv1, is an essential protein in mediating mitochondrial fission. Dnm1 and Fis1 are highly conserved, with a common mechanism in disparate species. In mutants of these proteins, mitochondrial fission is impaired, resulting in networks of undivided mitochondria. The Fis1 N-terminus is cytosolic and tethered to the mitochondrial outer membrane via a C-terminal transmembrane domain. Fis1 appears to act via the recruitment of division complexes to the mitochondrial outer membrane, via interactions with Mdv1 or Caf4. Fis1 has tandem Tetratricopeptide repeat (TPR) motifs which are known to mediate protein-protein interactions.


Pssm-ID: 276936 [Multi-domain]  Cd Length: 115  Bit Score: 38.30  E-value: 2.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1839555803 310 FLLAqLAYANSK-YERALIYTDRALDIDPRNMEALLLR 346
Cdd:cd12212    67 YYLA-LGHYKLGeYSEARRYVDALLEIEPDNRQALALK 103
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
311-471 3.39e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.51  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 311 LLAQLAYANSKYERALIYTDRAldidprnmEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRM 390
Cdd:COG4785    52 ALAAAALAAERIDRALALPDLA--------QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDY 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 391 KESHNMCALAVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYaPGIALMAGIFQHEGAAQEAIGLLRK 470
Cdd:COG4785   124 DAALEDFDRALELDPDYAYAYLNRGIALYYLGRYE---LAIADLEKALELDPND-PERALWLYLAERKLDPEKALALLLE 199


                  .
gi 1839555803 471 Q 471
Cdd:COG4785   200 D 200
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 321-476 3.45e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 321 KYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFRTAQCLGPYRFEIYKGLLACYIRQKRMKESHNMCALA 400
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839555803 401 VRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP 476
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKD---EAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 233-349 4.53e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 4.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 233 QNHHLLTNIGKCLYYYGNFIQAELYLETAARNNTYNMNAIGLLAVVYEYNGKkNVEQETLIAPIRTRSTGEFKSphWFLL 312
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGD-TEEAEELLERALALDPDNPEA--LYLL 91

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1839555803 313 AQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKL 349
Cdd:COG4235    92 GLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 400-509 5.48e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 5.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 400 AVRYFSTSPRSYTMFGHTLFHSSNPQvkkSAKKFVEKALQIDEHYAPGIALMAGIFQHEGAAQEAIGLLRKQVTNYP-HP 478
Cdd:COG4235     9 ALAANPNDAEGWLLLGRAYLRLGRYD---EALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPdNP 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1839555803 479 KLFAMLAELLSSEKDLDGALHFYMKALRMEP 509
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 311-510 7.96e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 311 LLAQLAYANSKYERALIYTDRALDIDPRNMEALLLRGKLFGGLGRNEEAIQAFR--------TAQCLGPYRFEIYKGLLA 382
Cdd:COG3071    90 TRAELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPalrkhkalSAEEAQALERRAYLGLLR 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839555803 383 CYIRQ--------KRM-KESHNMCALAVRYFstspRSYTMFGHTlfhssnpqvkKSAKKFVEKALqiDEHYAPG-IALMA 452
Cdd:COG3071   170 QAARDaealkalwKALpRAERRDPELAAAYA----RALIALGDH----------DEAERLLREAL--KRQWDPRlVRLYG 233

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1839555803 453 GIfqHEGAAQEAIGLLRKQVTNYPH-PKLFAMLAELLSSEKDLDGALHFYMKALRMEPT 510
Cdd:COG3071   234 RL--QGGDPAKQLKRAEKWLKKHPNdPDLLLALGRLCLRNQLWGKAREYLEAALALRPS 290
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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