NCBI Conserved Domain Search

Conserved domains on [gi|1826627506|ref|XP_033102248|]

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NADH-ubiquinone oxidoreductase subunit 8-like [Anneissia japonica]

Protein Classification

NuoI/complex I 23 kDa subunit family protein( domain architecture ID 11481829)

NuoI/complex I 23 kDa subunit family protein such as bacterial NADH-quinone oxidoreductase subunit I (NuoI), which is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

EC: 7.1.1.-

Gene Ontology: GO:0016651|GO:0051539|GO:0016020

PubMed: 23417064|33957129|24059520

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

68-224

5.67e-94

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 271.76 E-value: 5.67e-94

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  68 RAARTLFLGEIFRGLAMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEER 147
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 148 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLDNGDKWEAEIAANIQADHLYR 224
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

68-224

5.67e-94

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 271.76 E-value: 5.67e-94

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  68 RAARTLFLGEIFRGLAMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEER 147
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 148 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLDNGDKWEAEIAANIQADHLYR 224
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

NuoI

TIGR01971

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...

81-202

8.51e-64

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]

Pssm-ID: 273902 [Multi-domain] Cd Length: 122 Bit Score: 193.79 E-value: 8.51e-64

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  81 GLAMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDID 160
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1826627506 161 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 202
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122

NuoI

COG1143

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...

122-194

4.21e-22

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase

Pssm-ID: 440758 [Multi-domain] Cd Length: 66 Bit Score: 85.57 E-value: 4.21e-22

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERadgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 194
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEP------GKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

122-180

6.05e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 71.27 E-value: 6.05e-16

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd10549    77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126

Fer4_7

pfam12838

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

125-178

9.83e-13

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.

Pssm-ID: 463724 [Multi-domain] Cd Length: 51 Bit Score: 60.62 E-value: 9.83e-13

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 125 CIACKLCEAICPAQAITIEAEERADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 178
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51

ferrodoxin_EFR1

NF038196

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...

89-179

8.11e-06

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).

Pssm-ID: 468407 [Multi-domain] Cd Length: 243 Bit Score: 45.24 E-value: 8.11e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  89 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSrrttrydidmtKCIYCG 168
Cdd:NF038196  151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGKPVWGH-----------NCTHCL 219

                          90
                  ....*....|.
gi 1826627506 169 FCQEACPVDAI 179
Cdd:NF038196  220 ACIHRCPKEAI 230

Name

Accession

Description

Interval

E-value

PRK05888

NADH-quinone oxidoreductase subunit NuoI;

68-224

5.67e-94

NADH-quinone oxidoreductase subunit NuoI;

Pssm-ID: 235637 [Multi-domain] Cd Length: 164 Bit Score: 271.76 E-value: 5.67e-94

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  68 RAARTLFLGEIFRGLAMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEER 147
Cdd:PRK05888    3 QYLKSMLLKELLKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAER 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 148 ADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLDNGDKWEAEIAANIQADHLYR 224
Cdd:PRK05888   83 EDGRRRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGDRVEREIAPGKAADANYR 159

NuoI

TIGR01971

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...

81-202

8.51e-64

Pssm-ID: 273902 [Multi-domain] Cd Length: 122 Bit Score: 193.79 E-value: 8.51e-64

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  81 GLAMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDID 160
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEIN 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1826627506 161 MTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKL 202
Cdd:TIGR01971  81 FGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122

NuoI

COG1143

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...

122-194

4.21e-22

Pssm-ID: 440758 [Multi-domain] Cd Length: 66 Bit Score: 85.57 E-value: 4.21e-22

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERadgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVEGPnFEFSTETHEE 194
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEP------GKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66

ndhI

CHL00014

NADH dehydrogenase subunit I

66-199

5.11e-20

NADH dehydrogenase subunit I

Pssm-ID: 214334 [Multi-domain] Cd Length: 167 Bit Score: 83.27 E-value: 5.11e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  66 TDRAARTlflgeIFRGLAMTLSYLFREPATINYPFEKGPLSPRFRGehalrRYPSGEERCIACKLCEAICPAQAITIEAE 145
Cdd:CHL00014   12 TIRAARY-----IGQGFMITLSHANRLPVTIQYPYEKLITSERFRG-----RIHFEFDKCIACEVCVRVCPIDLPVVDWK 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 146 ERAD-GSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNK 199
Cdd:CHL00014   82 LETDiRKKRLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQ 136

PRK12387

formate hydrogenlyase complex iron-sulfur subunit; Provisional

93-200

2.18e-17

formate hydrogenlyase complex iron-sulfur subunit; Provisional

Pssm-ID: 183492 [Multi-domain] Cd Length: 180 Bit Score: 76.61 E-value: 2.18e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  93 PATINYPFEKGPLSPRFRG--EHALrrypsgeERCIACKLCEAICPAQAITIEAEERADgsrrTTRYDIDMTKCIYCGFC 170
Cdd:PRK12387   13 TATSSYPLEPIAVDKNFRGkpEYNP-------QQCIGCAACVNACPSNALTVETDLATG----ELAWEFNLGRCIFCGRC 81

                          90       100       110
                  ....*....|....*....|....*....|
gi 1826627506 171 QEACPVDAIVEGPNFEFSTETHEELLYNKE 200
Cdd:PRK12387   82 EEVCPTAAIKLSQEFELAVWKKEDLLQQSE 111

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

122-180

6.05e-16

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 71.27 E-value: 6.05e-16

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADgsrrttrydIDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd10549    77 EEKCIGCGLCVKVCPVDAITLEDELEIV---------IDKEKCIGCGICAEVCPVNAIK 126

PRK08222

hydrogenase 4 subunit H; Validated

94-199

6.77e-16

hydrogenase 4 subunit H; Validated

Pssm-ID: 181301 [Multi-domain] Cd Length: 181 Bit Score: 72.48 E-value: 6.77e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  94 ATINYPFEKGPLSPRFRGEHALrrypsGEERCIACKLCEAICPAQAITIEAEERADgsrrTTRYDIDMTKCIYCGFCQEA 173
Cdd:PRK08222   14 ATVKYPFAPLEVSPGFRGKPDL-----MPSQCIACGACTCACPANALTIQTDDQQN----SRTWQLYLGRCIYCGRCEEV 84

                          90       100
                  ....*....|....*....|....*.
gi 1826627506 174 CPVDAIVEGPNFEFsTETHEELLYNK 199
Cdd:PRK08222   85 CPTRAIQLTNNFEL-TVTNKADLYTR 109

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

122-201

2.04e-14

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 67.42 E-value: 2.04e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERAdgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEK 201
Cdd:cd10549     5 PEKCIGCGICVKACPTDAIELGPNGAI-----ARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEEK 79

COG2768

Uncharacterized Fe-S cluster protein [Function unknown];

113-186

2.32e-14

Uncharacterized Fe-S cluster protein [Function unknown];

Pssm-ID: 442050 [Multi-domain] Cd Length: 74 Bit Score: 65.52 E-value: 2.32e-14

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 113 HALRRYPSGEERCIACKLCEAICPAQAITIEAEeradgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGPNFE 186
Cdd:COG2768     1 HSLGKPYVDEEKCIGCGACVKVCPVGAISIEDG----------KAVIDPEKCIGCGACIEVCPVGAIKIEWEED 64

DsrA

COG2221

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...

122-187

2.76e-14

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];

Pssm-ID: 441823 [Multi-domain] Cd Length: 69 Bit Score: 65.46 E-value: 2.76e-14

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEeradgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEF 187
Cdd:COG2221    14 EEKCIGCGLCVAVCPTGAISLDDG----------KLVIDEEKCIGCGACIRVCPTGAIKGEKPKKF 69

PRK13984

putative oxidoreductase; Provisional

88-174

2.01e-13

putative oxidoreductase; Provisional

Pssm-ID: 172486 [Multi-domain] Cd Length: 604 Bit Score: 68.64 E-value: 2.01e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  88 YLFREPATINYPFEKGPLSPRFRGEHAlrrypSGEERCIACKLCEAICPAQAIT-IEAEERADG-SRRTTRYDIDMTKCI 165
Cdd:PRK13984   15 FLFRKPVTIKVPNVKREAAERYRGFHI-----NDWEKCIGCGTCSKICPTDAITmVEVPDLPQEyGKKPQRPVIDYGRCS 89


                  ....*....
gi 1826627506 166 YCGFCQEAC 174
Cdd:PRK13984   90 FCALCVDIC 98

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

122-179

5.71e-13

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 63.57 E-value: 5.71e-13

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEaEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10549    39 EDKCVFCGACVEVCPTGAIELT-PEGKEYVPKEKEAEIDEEKCIGCGLCVKVCPVDAI 95

Fer4_7

pfam12838

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

125-178

9.83e-13

Pssm-ID: 463724 [Multi-domain] Cd Length: 51 Bit Score: 60.62 E-value: 9.83e-13

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 125 CIACKLCEAICPAQAITIEAEERADGsrrTTRYDIDMTKCIYCGFCQEACPVDA 178
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKG---TKTVVIDPERCVGCGACVAVCPTGA 51

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

122-180

3.03e-12

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 60.06 E-value: 3.03e-12

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEaeeraDGSRRttrydIDMTKCIYCGFCQEACPVDAIV 180
Cdd:COG4231    21 EDKCTGCGACVKVCPADAIEEG-----DGKAV-----IDPDLCIGCGSCVQVCPVDAIK 69

PorD

COG1144

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...

122-180

7.06e-12

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation

Pssm-ID: 440759 [Multi-domain] Cd Length: 84 Bit Score: 59.30 E-value: 7.06e-12

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEeradgsrrtTRYDIDMTKCIYCGFCQEACPVDAIV 180
Cdd:COG1144    29 EDKCIGCGLCWIVCPDGAIRVDDG---------KYYGIDYDYCKGCGICAEVCPVKAIE 78

PRK08348

NADH-plastoquinone oxidoreductase subunit; Provisional

82-190

1.57e-11

NADH-plastoquinone oxidoreductase subunit; Provisional

Pssm-ID: 181399 [Multi-domain] Cd Length: 120 Bit Score: 59.46 E-value: 1.57e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  82 LAMTLSYLFREPATINYP-FEKGPLSPRFRGEHALRRypsgeERCIACKLCEAICPAQAITIEAEERadgsrrttRYDID 160
Cdd:PRK08348    5 LPTVLRNLFKKPATNLFPaTEPVPVPEDFRGKILYDV-----DKCVGCRMCVTVCPAGVFVYLPEIR--------KVALW 71

                          90       100       110
                  ....*....|....*....|....*....|
gi 1826627506 161 MTKCIYCGFCQEACPVDAIVEGPNFEFSTE 190
Cdd:PRK08348   72 TGRCVFCGQCVDVCPTGALQMSDDFLLASY 101

COG1149

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...

122-183

1.64e-11

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];

Pssm-ID: 440763 [Multi-domain] Cd Length: 68 Bit Score: 57.82 E-value: 1.64e-11

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERadgsrrttrYDIDMTKCIYCGFCQEACPVDAIVEGP 183
Cdd:COG1149    10 EEKCIGCGLCVEVCPEGAIKLDDGGA---------PVVDPDLCTGCGACVGVCPTGAITLEE 62

NapF

COG1145

Ferredoxin [Energy production and conversion];

122-179

3.40e-11

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 60.89 E-value: 3.40e-11

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERAdgsrrttrYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG1145   181 AEKCIGCGLCVKVCPTGAIRLKDGKPQ--------IVVDPDKCIGCGACVKVCPVGAI 230

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

122-179

5.80e-11

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 56.26 E-value: 5.80e-11

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEeradgSRRTTRYDIDmtKCIYCGFCQEACPVDAI 179
Cdd:COG1146     7 TDKCIGCGACVEVCPVDVLELDEE-----GKKALVINPE--ECIGCGACELVCPVGAI 57

Nar1

COG4624

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

122-181

1.59e-09

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

Pssm-ID: 443663 [Multi-domain] Cd Length: 450 Bit Score: 56.96 E-value: 1.59e-09

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 122 EERCIACKLCEAICPAQAITIEaEERADgsrrttrydIDMTKCIYCGFCQEACPVDAIVE 181
Cdd:COG4624    90 KEKCKNCYPCVRACPVKAIKVD-DGKAE---------IDEEKCISCGQCVAVCPFGAITE 139

PRK07118

Fe-S cluster domain-containing protein;

125-181

2.34e-09

Fe-S cluster domain-containing protein;

Pssm-ID: 235941 [Multi-domain] Cd Length: 280 Bit Score: 56.09 E-value: 2.34e-09

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 125 CIACKLCEAICPAQAITIEaeeradgsrrTTRYDIDMTKCIYCGFCQEACPVDAIVE 181
Cdd:PRK07118  215 CIGCGKCVKACPAGAITME----------NNLAVIDQEKCTSCGKCVEKCPTKAIRI 261

HdrA

COG1148

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];

122-179

3.06e-09

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];

Pssm-ID: 440762 [Multi-domain] Cd Length: 563 Bit Score: 56.02 E-value: 3.06e-09

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERAdgsrrttryDIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG1148   495 PEKCTGCGRCVEVCPYGAISIDEKGVA---------EVNPALCKGCGTCAAACPSGAI 543

Fer4_9

pfam13187

4Fe-4S dicluster domain;

124-179

4.20e-09

4Fe-4S dicluster domain;

Pssm-ID: 463801 [Multi-domain] Cd Length: 50 Bit Score: 51.02 E-value: 4.20e-09

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 124 RCIACKLCEAICPAQAITIeaeeraDGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVP------DLVGQTIRGDIAGLACIGCGACVDACPRGAI 50

PRK06273

ferredoxin; Provisional

122-176

3.15e-08

ferredoxin; Provisional

Pssm-ID: 235764 [Multi-domain] Cd Length: 165 Bit Score: 51.25 E-value: 3.15e-08

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAIT---IEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPV 176
Cdd:PRK06273   48 EELCIGCGGCANVCPTKAIEmipVEPVKITEGYVKTKIPKIDYEKCVYCLYCHDFCPV 105

FeFe_hydrog_B1

TIGR04105

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.

123-181

7.23e-08

[FeFe] hydrogenase, group B1/B3; See for descriptions of different groups.

Pssm-ID: 274983 [Multi-domain] Cd Length: 462 Bit Score: 52.21 E-value: 7.23e-08

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 123 ERCIACKLC----------------EAICPAQAITIEAEERADgsrrttrydIDMTKCIYCGFCQEACPVDAIVE 181
Cdd:TIGR04105 142 EKCIECGKCkkacpynaiveierpcEKACPVGAISSDEDGRAV---------IDYDKCISCGACMVACPFGAISD 207

PRK14028

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional

124-179

7.31e-08

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional

Pssm-ID: 172522 [Multi-domain] Cd Length: 312 Bit Score: 51.92 E-value: 7.31e-08

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 124 RCIACKLCEAICPAQAItIEAEERADGSR----RTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:PRK14028  248 KCIMCRKCWLYCPDDAI-IEAWREAEGPRgrkfRMKMIDFDYQYCKGCGVCAEVCPTGAI 306

PsrB

cd10551

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...

123-188

3.83e-07

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.

Pssm-ID: 319873 [Multi-domain] Cd Length: 185 Bit Score: 48.68 E-value: 3.83e-07

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 123 ERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYC------G---FCQEACPVDAIVEG----PNFEFS 188
Cdd:cd10551    83 DKCIGCRYCMAACPYGARYFNPEEPHEFGEVPVRPKGVVEKCTFCyhrldeGllpACVEACPTGARIFGdlddPNSEVS 161

PRK13795

hypothetical protein; Provisional

124-176

4.41e-07

hypothetical protein; Provisional

Pssm-ID: 237510 [Multi-domain] Cd Length: 636 Bit Score: 49.99 E-value: 4.41e-07

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 124 RCIACKLCEAICPAQAITIEAEERadgsrrttRYDIDMTKCIYCGFCQEACPV 176
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGKR--------KISVDEEKCIHCGKCTEVCPV 626

HybA

COG0437

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...

113-180

6.00e-07

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];

Pssm-ID: 440206 [Multi-domain] Cd Length: 184 Bit Score: 48.02 E-value: 6.00e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 113 HALRRYPSG-----EERCIACKLCEAICPAQAITIEAEERAdgsrrttrydidMTKCIYCGF---------CQEACPVDA 178
Cdd:COG0437    75 GATYKREDGivlvdYDKCIGCRYCVAACPYGAPRFNPETGV------------VEKCTFCADrldegllpaCVEACPTGA 142


                  ..
gi 1826627506 179 IV 180
Cdd:COG0437   143 LV 144

HycB_like

cd10554

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...

122-179

7.78e-07

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.

Pssm-ID: 319876 [Multi-domain] Cd Length: 149 Bit Score: 47.25 E-value: 7.78e-07

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDIdMTKCIYCGF------CQEACPVDAI 179
Cdd:cd10554    84 EERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAV-AVKCDLCAGreggpaCVEACPTKAL 146

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

125-179

1.12e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 46.57 E-value: 1.12e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 125 CIACKL--CEAICPAQAITieaeeradgsRRTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG1142    52 CRHCEDapCAEVCPVGAIT----------RDDGAVVVDEEKCIGCGLCVLACPFGAI 98

NapH

COG0348

Polyferredoxin NapH [Energy production and conversion];

122-179

1.28e-06

Polyferredoxin NapH [Energy production and conversion];

Pssm-ID: 440117 [Multi-domain] Cd Length: 263 Bit Score: 47.75 E-value: 1.28e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQaITIEAEEradgsrrttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG0348   209 RGDCIDCGLCVKVCPMG-IDIRKGE------------INQSECINCGRCIDACPKDAI 253

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

116-180

1.29e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 46.03 E-value: 1.29e-06

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 116 RRYPSGEERCIACKLCE-----AICPAQAITIEAEERAdgsrrttrYDIDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd10550    37 RFEPEGLDVPVVCRQCEdapcvEACPVGAISRDEETGA--------VVVDEDKCIGCGMCVEACPFGAIR 98

PRK12771

putative glutamate synthase (NADPH) small subunit; Provisional

125-183

1.35e-06

putative glutamate synthase (NADPH) small subunit; Provisional

Pssm-ID: 237198 [Multi-domain] Cd Length: 564 Bit Score: 48.33 E-value: 1.35e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 125 CIACKLCEAICPAQAITIEAEERadgsrrttRYDIDMTKCIYCGFCQEACPVDAIVEGP 183
Cdd:PRK12771  512 CFECDNCYGACPQDAIIKLGPGR--------RYHFDYDKCTGCHICADVCPCGAIEMGP 562

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

122-180

1.69e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 45.80 E-value: 1.69e-06

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGSrrttrydidmTKCIYCGF------CQEACPVDAIV 180
Cdd:COG1142    80 EEKCIGCGLCVLACPFGAITMVGEKSRAVA----------VKCDLCGGreggpaCVEACPTGALR 134

DMSOR_beta-like

cd04410

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...

112-180

2.00e-06

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319870 [Multi-domain] Cd Length: 136 Bit Score: 45.84 E-value: 2.00e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 112 EHALRRYPSG-----EERCIACKLCEAICPAQAITIEAEERadgsrrttrydiDMTKCIYCGF---------CQEACPVD 177
Cdd:cd04410    64 TGAIYKDEDGivlidEDKCIGCGSCVEACPYGAIVFDPEPG------------KAVKCDLCGDrldeglepaCVKACPTG 131


                  ...
gi 1826627506 178 AIV 180
Cdd:cd04410   132 ALT 134

DMSOR_beta_like

cd16373

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

122-180

2.50e-06

Pssm-ID: 319895 [Multi-domain] Cd Length: 154 Bit Score: 45.71 E-value: 2.50e-06

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIA------CKLCEAICPAQAITIEAEeraDGSRRTTrydIDMTKCIYCGFCQEACPVD---AIV 180
Cdd:cd16373    90 KDRCLAwqggtdCGVCVEACPTEAIAIVLE---DDVLRPV---VDEDKCVGCGLCEYVCPVEppkAIV 151

Fer4_10

pfam13237

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...

122-175

3.26e-06

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.

Pssm-ID: 404174 [Multi-domain] Cd Length: 56 Bit Score: 43.01 E-value: 3.26e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGSRRTtryDIDMTKCIYCGFCQEACP 175
Cdd:pfam13237   6 PDKCIGCGRCTAACPAGLTRVGAIVERLEGEAV---RIGVWKCIGCGACVEACP 56

Nar1

COG4624

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

124-179

3.92e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];

Pssm-ID: 443663 [Multi-domain] Cd Length: 450 Bit Score: 46.94 E-value: 3.92e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 124 RCIACKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG4624    53 RCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAI 108

NapF_like

cd10564

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...

126-179

5.16e-06

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.

Pssm-ID: 319886 [Multi-domain] Cd Length: 139 Bit Score: 44.54 E-value: 5.16e-06

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 126 IACKLCEAICPAQAITIEAEERADGSRRttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10564    86 VECRSCQDACPTQAIRFRPRLGGIALPE-----LDADACTGCGACVSVCPVGAI 134

ferrodoxin_EFR1

NF038196

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...

89-179

8.11e-06

Pssm-ID: 468407 [Multi-domain] Cd Length: 243 Bit Score: 45.24 E-value: 8.11e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506  89 LFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSrrttrydidmtKCIYCG 168
Cdd:NF038196  151 GPEKKKGFIPRLLSKLVNPLFYKFKVKDKKFHVTDKCIGCGICAKVCPVNNIEMEDGKPVWGH-----------NCTHCL 219

                          90
                  ....*....|.
gi 1826627506 169 FCQEACPVDAI 179
Cdd:NF038196  220 ACIHRCPKEAI 230

HybA

COG0437

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...

131-179

1.07e-05

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];

Pssm-ID: 440206 [Multi-domain] Cd Length: 184 Bit Score: 44.55 E-value: 1.07e-05

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1826627506 131 CEAICPAQAITIeaeeRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG0437    68 CVKVCPTGATYK----REDGIVL-----VDYDKCIGCRYCVAACPYGAP 107

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

122-179

1.25e-05

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 43.33 E-value: 1.25e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERAdgsrrttrydidMTKCIYCG---FCQEACPVDAI 179
Cdd:cd10550    79 EDKCIGCGMCVEACPFGAIRVDPETGK------------AIKCDLCGgdpACVKVCPTGAL 127

Fer4

pfam00037

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...

157-179

1.39e-05

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.

Pssm-ID: 459642 [Multi-domain] Cd Length: 24 Bit Score: 40.69 E-value: 1.39e-05

                          10        20
                  ....*....|....*....|...
gi 1826627506 157 YDIDMTKCIYCGFCQEACPVDAI 179
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAI 23

Fer4_16

pfam13484

4Fe-4S double cluster binding domain;

125-175

1.56e-05

4Fe-4S double cluster binding domain;

Pssm-ID: 463893 [Multi-domain] Cd Length: 65 Bit Score: 41.71 E-value: 1.56e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 125 CIACKLCEAICPAQAIT---IEAEERADGSRRTTRYD---------IDMTKCIYCGFCQEACP 175
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVgpeGVLDARRCISYLTIEKKglipdelrcLLGNRCYGCDICQDVCP 63

DMSOR_beta_like

cd16373

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

124-179

1.65e-05

Pssm-ID: 319895 [Multi-domain] Cd Length: 154 Bit Score: 43.40 E-value: 1.65e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 124 RCIACKLCEAICPAQAITIEAEEraDGSR--RTTRYDIDMTKCIYCG-FCQEACPVDAI 179
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQPAGLE--DGLEggRTPYLDPREGPCDLCCdACVEVCPTGAL 71

vorD

PRK09623

3-methyl-2-oxobutanoate dehydrogenase subunit delta;

122-179

2.01e-05

3-methyl-2-oxobutanoate dehydrogenase subunit delta;

Pssm-ID: 170016 [Multi-domain] Cd Length: 105 Bit Score: 42.24 E-value: 2.01e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIeaeeRADGSrrttrYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:PRK09623   50 ESKCVKCYICWKFCPEPAIYI----KEDGY-----VAIDYDYCKGCGICANECPTKAI 98

DMSOR_beta-like

cd04410

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...

123-180

2.02e-05

Pssm-ID: 319870 [Multi-domain] Cd Length: 136 Bit Score: 42.76 E-value: 2.02e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 123 ERCIACK--LCEAICPAQAItieaEERADGsrrttRYDIDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd04410    48 VSCMHCEdpPCVKACPTGAI----YKDEDG-----IVLIDEDKCIGCGSCVEACPYGAIV 98

NapF

COG1145

Ferredoxin [Energy production and conversion];

121-184

3.38e-05

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 43.56 E-value: 3.38e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 121 GEERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPN 184
Cdd:COG1145   141 EAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDG 204

PRK09898

ferredoxin-like protein;

122-179

3.63e-05

ferredoxin-like protein;

Pssm-ID: 182135 [Multi-domain] Cd Length: 208 Bit Score: 43.29 E-value: 3.63e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADgsrrttrydidmTKCIYCGFCQEACPVDAI 179
Cdd:PRK09898  153 HKRCIGCSACTTACPWMMATVNTESKKS------------SKCVLCGECANACPTGAL 198

rnfB

TIGR01944

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...

122-180

5.42e-05

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]

Pssm-ID: 273887 [Multi-domain] Cd Length: 165 Bit Score: 42.09 E-value: 5.42e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITieaeeradGSRRTTRYDIdMTKCIYCGFCQEACPVDAIV 180
Cdd:TIGR01944 112 EDNCIGCTKCIQACPVDAIV--------GAAKAMHTVI-ADECTGCDLCVEPCPTDCIE 161

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

153-184

6.36e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 40.03 E-value: 6.36e-05

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1826627506 153 RTT--RYDIDMTKCIYCGFCQEACPVDAIVEGPN 184
Cdd:COG4231    11 RTTamRYVIDEDKCTGCGACVKVCPADAIEEGDG 44

PsrB

cd10551

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...

131-179

7.22e-05

Pssm-ID: 319873 [Multi-domain] Cd Length: 185 Bit Score: 42.13 E-value: 7.22e-05

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1826627506 131 CEAICPAQAITIeaeeRADGsrrttRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10551    61 CVKVCPTGATYK----REDG-----IVLVDYDKCIGCRYCMAACPYGAR 100

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

122-150

9.20e-05

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 39.31 E-value: 9.20e-05

                          10        20
                  ....*....|....*....|....*....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADG 150
Cdd:COG1146    39 PEECIGCGACELVCPVGAITVEDDEPEEQ 67

DMSOR_beta_like

cd16370

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

125-179

9.40e-05

Pssm-ID: 319892 [Multi-domain] Cd Length: 131 Bit Score: 40.72 E-value: 9.40e-05

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 125 CIACKL--CEAICPAQAItieaEERADGSRRTTRydidmTKCIYCGFCQEACPVDAI 179
Cdd:cd16370    53 CRACEDppCAEACPTGAL----EPRKGGGVVLDK-----EKCIGCGNCVKACIVGAI 100

PreA

COG1146

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...

159-194

1.02e-04

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];

Pssm-ID: 440761 [Multi-domain] Cd Length: 67 Bit Score: 39.31 E-value: 1.02e-04

                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1826627506 159 IDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE 194
Cdd:COG1146     5 IDTDKCIGCGACVEVCPVDVLELDEEGKKALVINPE 40

porD

PRK09624

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed

122-180

1.07e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed

Pssm-ID: 170017 [Multi-domain] Cd Length: 105 Bit Score: 40.40 E-value: 1.07e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEEradgsrrttrYDI-DMTKCIYCGFCQEACPVDAIV 180
Cdd:PRK09624   50 RDKCVRCYLCYIYCPEPAIYLDEEG----------YPVfDYDYCKGCGICANECPTKAIE 99

PRK07118

Fe-S cluster domain-containing protein;

122-180

1.14e-04

Fe-S cluster domain-containing protein;

Pssm-ID: 235941 [Multi-domain] Cd Length: 280 Bit Score: 42.23 E-value: 1.14e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 122 EERCIACKLCEAICPAQAIT-IEAEERADGSRRTTRYDIDMTK-----CIYCGFCQEACPVDAIV 180
Cdd:PRK07118  167 EDKCTGCGACVKACPRNVIElIPKSARVFVACNSKDKGKAVKKvcevgCIGCGKCVKACPAGAIT 231

RnfB

COG2878

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...

122-179

1.15e-04

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase

Pssm-ID: 442125 [Multi-domain] Cd Length: 254 Bit Score: 41.90 E-value: 1.15e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAeeraDGSRRttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG2878   136 EYGCIGCGDCIKACPFDAIVGAA----KGMHT-----VDEDKCTGCGLCVEACPVDCI 184

DMSOR_beta_like

cd16371

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

131-180

1.34e-04

Pssm-ID: 319893 [Multi-domain] Cd Length: 140 Bit Score: 40.62 E-value: 1.34e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1826627506 131 CEAICPAQAITIeaeeRADGsrrTTRYDIDmtKCIYCGFCQEACPVDAIV 180
Cdd:cd16371    62 CVKVCPTGAITK----REDG---IVVVDQD--KCIGCGYCVWACPYGAPQ 102

PRK12769

putative oxidoreductase Fe-S binding subunit; Reviewed

122-179

1.37e-04

putative oxidoreductase Fe-S binding subunit; Reviewed

Pssm-ID: 183733 [Multi-domain] Cd Length: 654 Bit Score: 42.43 E-value: 1.37e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGSRRTTRYdidmtKCIYCG------FCQEACPVDAI 179
Cdd:PRK12769   84 QQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKATAH-----KCDLCAgrengpACVENCPADAL 142

NapF_like

cd10564

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...

116-179

1.45e-04

Pssm-ID: 319886 [Multi-domain] Cd Length: 139 Bit Score: 40.69 E-value: 1.45e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 116 RRYPSGEE-----RCIACKLCEAICPAQAITIeaeeradGSRRTTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10564     1 RPPWAVDEalfldLCTRCGDCVEACPEGIIVR-------GDGGFPELDFSRGECTFCGACAEACPEGAL 62

PRK08318

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;

122-181

1.58e-04

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;

Pssm-ID: 236237 [Multi-domain] Cd Length: 420 Bit Score: 41.85 E-value: 1.58e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 122 EERCIACKLCEAIC---PAQAITIEAeeraDGSRRttrYDIDMTKCIYCGFCQEACPVDAIVE 181
Cdd:PRK08318  341 QDKCIGCGRCYIACedtSHQAIEWDE----DGTRT---PEVIEEECVGCNLCAHVCPVEGCIT 396

HycB

COG1142

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

123-185

2.64e-04

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];

Pssm-ID: 440757 [Multi-domain] Cd Length: 138 Bit Score: 39.64 E-value: 2.64e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 123 ERCIACKLCEAICPAQAITIEAEERADGSRRTTRYDIDM-TKCIYC--GFCQEACPVDAIVEGPNF 185
Cdd:COG1142    10 EKCIGCRTCEAACAVAHEGEEGEPFLPRIRVVRKAGVSApVQCRHCedAPCAEVCPVGAITRDDGA 75

COG1149

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...

159-180

2.72e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];

Pssm-ID: 440763 [Multi-domain] Cd Length: 68 Bit Score: 38.17 E-value: 2.72e-04

                          10        20
                  ....*....|....*....|..
gi 1826627506 159 IDMTKCIYCGFCQEACPVDAIV 180
Cdd:COG1149     8 IDEEKCIGCGLCVEVCPEGAIK 29

DMSOR_beta_like

cd16370

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

114-179

2.77e-04

Pssm-ID: 319892 [Multi-domain] Cd Length: 131 Bit Score: 39.56 E-value: 2.77e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 114 ALRRYPSG-----EERCIACKLCEAICPAQAITIEAEeradgsrrtTRYDIdmtKCIYCGFCQEACPVDAI 179
Cdd:cd16370    69 ALEPRKGGgvvldKEKCIGCGNCVKACIVGAIFWDEE---------TNKPI---ICIHCGYCARYCPHDVL 127

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

114-179

2.97e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 39.24 E-value: 2.97e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 114 ALRRYPSG-----EERCIACKLCEAICPAQAItIEAEERadgsrrttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd16372    63 AITRDANGvvminKKLCVGCLMCVGFCPEGAM-FKHEDY-----------PEPFKCIACGICVKACPTGAL 121

rnfB

TIGR01944

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...

159-185

2.99e-04

Pssm-ID: 273887 [Multi-domain] Cd Length: 165 Bit Score: 40.17 E-value: 2.99e-04

                          10        20
                  ....*....|....*....|....*..
gi 1826627506 159 IDMTKCIYCGFCQEACPVDAIVEGPNF 185
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACPVDAIVGAAKA 136

PorD

COG1144

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...

150-190

3.46e-04

Pssm-ID: 440759 [Multi-domain] Cd Length: 84 Bit Score: 38.11 E-value: 3.46e-04

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1826627506 150 GSRRTTRYDIDMTKCIYCGFCQEACPVDAI--VEGPNFEFSTE 190
Cdd:COG1144    18 GGWRVERPVVDEDKCIGCGLCWIVCPDGAIrvDDGKYYGIDYD 60

DMSOR_beta-like

cd04410

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...

122-183

3.57e-04

Pssm-ID: 319870 [Multi-domain] Cd Length: 136 Bit Score: 39.29 E-value: 3.57e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 122 EERCIACKLCEAICPaQAITIEAEERADGSRRTTRYDIDM----TKCIYCGF--CQEACPVDAIVEGP 183
Cdd:cd04410     5 LDRCIGCGTCEVACK-QEHGLRPGPDWSRIKVIEGGGLERaflpVSCMHCEDppCVKACPTGAIYKDE 71

DMSOR_beta_like

cd16374

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

124-179

3.92e-04

Pssm-ID: 319896 [Multi-domain] Cd Length: 139 Bit Score: 39.18 E-value: 3.92e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 124 RCIACK--LCEAICPAQAITIEAEERADgsrrttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd16374    42 RCRHCEdaPCMEVCPTGAIYRDEDGAVL---------VDPDKCIGCGMCAMACPFGVP 90

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

122-184

4.02e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 38.86 E-value: 4.02e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICpaqAITIEAEERADGSR---RTTRYDIDMTKCIYCGFCQEACPVDAIVEGPN 184
Cdd:cd16372     7 PEKCIGCLQCEEAC---SKTFFKEEDREKSCiriTETEGGYAINVCNQCGECIDVCPTGAITRDAN 69

PRK06991

electron transport complex subunit RsxB;

110-183

4.38e-04

electron transport complex subunit RsxB;

Pssm-ID: 235903 [Multi-domain] Cd Length: 270 Bit Score: 40.16 E-value: 4.38e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 110 RGEHALRRYPSGEERCIAcKLCEAI-CPAqaITIEAEERADGSRRTTRydIDMTKCIYCGFCQEACPVDAIVEGP 183
Cdd:PRK06991   37 AGEANYNRCPPGGAEGIA-RLAALLgKPV--IPLDPANGVERPRAVAV--IDEQLCIGCTLCMQACPVDAIVGAP 106

COG1149

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...

122-146

5.18e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];

Pssm-ID: 440763 [Multi-domain] Cd Length: 68 Bit Score: 37.40 E-value: 5.18e-04

                          10        20
                  ....*....|....*....|....*
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEE 146
Cdd:COG1149    40 PDLCTGCGACVGVCPTGAITLEERE 64

PRK09898

ferredoxin-like protein;

123-175

5.29e-04

ferredoxin-like protein;

Pssm-ID: 182135 [Multi-domain] Cd Length: 208 Bit Score: 39.82 E-value: 5.29e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1826627506 123 ERCIACK--LCEAICPAQAITIEAEERAdgsrrttrYDIDMTKCIYCGFCQEACP 175
Cdd:PRK09898  121 DTCRQCKepQCMNVCPIGAITWQQKEGC--------ITVDHKRCIGCSACTTACP 167

DMSOR_beta_like

cd10550

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

123-179

6.73e-04

Pssm-ID: 319872 [Multi-domain] Cd Length: 130 Bit Score: 38.33 E-value: 6.73e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 123 ERCIACKLCEAIC---------PAQA-ITIEAEERADgsrrttrYDIDMTkCIYCG--FCQEACPVDAI 179
Cdd:cd10550     6 EKCTGCRTCELACslkhegvfnPSLSrIRVVRFEPEG-------LDVPVV-CRQCEdaPCVEACPVGAI 66

DMSOR_beta_like

cd16372

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

125-180

7.07e-04

Pssm-ID: 319894 [Multi-domain] Cd Length: 125 Bit Score: 38.47 E-value: 7.07e-04

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 125 CIACKLCEAICPAQAITieaeeradgsrRTTR--YDIDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd16372    49 CNQCGECIDVCPTGAIT-----------RDANgvVMINKKLCVGCLMCVGFCPEGAMF 95

Fer4_8

pfam13183

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...

124-177

7.92e-04

Pssm-ID: 433017 [Multi-domain] Cd Length: 64 Bit Score: 36.91 E-value: 7.92e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 124 RCIACKLCEAICPA---------QAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVD 177
Cdd:pfam13183   1 RCIRCGACLAACPVylvtggrfpGDPRGGAAALLGRLEALEGLAEGLWLCTLCGACTEVCPVG 63

IorA

COG4231

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...

122-148

9.17e-04

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];

Pssm-ID: 443375 [Multi-domain] Cd Length: 76 Bit Score: 36.94 E-value: 9.17e-04

                          10        20
                  ....*....|....*....|....*..
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERA 148
Cdd:COG4231    50 PDLCIGCGSCVQVCPVDAIKLEKRVPE 76

DMSOR_beta_like

cd16374

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

123-190

1.37e-03

Pssm-ID: 319896 [Multi-domain] Cd Length: 139 Bit Score: 37.64 E-value: 1.37e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1826627506 123 ERCIACKLCEAICPAQAITIEAEERAdgsrrttrydidMTKCIYCG---------FCQEACPVDAIVEGPNFEFSTE 190
Cdd:cd16374    73 DKCIGCGMCAMACPFGVPRFDPSLKV------------AVKCDLCIdrrregklpACVEACPTGALKFGDIEELLKE 137

Fer4

pfam00037

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...

122-141

2.13e-03

Pssm-ID: 459642 [Multi-domain] Cd Length: 24 Bit Score: 34.53 E-value: 2.13e-03

                          10        20
                  ....*....|....*....|
gi 1826627506 122 EERCIACKLCEAICPAQAIT 141
Cdd:pfam00037   5 EEKCIGCGACVEVCPVGAIT 24

COG2768

Uncharacterized Fe-S cluster protein [Function unknown];

122-157

2.14e-03

Uncharacterized Fe-S cluster protein [Function unknown];

Pssm-ID: 442050 [Multi-domain] Cd Length: 74 Bit Score: 35.86 E-value: 2.14e-03

                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGSRRTTRY 157
Cdd:COG2768    39 PEKCIGCGACIEVCPVGAIKIEWEEDEEFQEKMAEY 74

DsrA

COG2221

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...

154-179

2.57e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];

Pssm-ID: 441823 [Multi-domain] Cd Length: 69 Bit Score: 35.41 E-value: 2.57e-03

                          10        20
                  ....*....|....*....|....*.
gi 1826627506 154 TTRYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:COG2221     7 TWPPKIDEEKCIGCGLCVAVCPTGAI 32

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

158-184

2.62e-03

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 36.61 E-value: 2.62e-03

                          10        20
                  ....*....|....*....|....*..
gi 1826627506 158 DIDMTKCIYCGFCQEACPVDAIVEGPN 184
Cdd:cd10549     2 KYDPEKCIGCGICVKACPTDAIELGPN 28

PRK05113

electron transport complex protein RnfB; Provisional

159-180

2.70e-03

electron transport complex protein RnfB; Provisional

Pssm-ID: 235347 [Multi-domain] Cd Length: 191 Bit Score: 37.62 E-value: 2.70e-03

                          10        20
                  ....*....|....*....|..
gi 1826627506 159 IDMTKCIYCGFCQEACPVDAIV 180
Cdd:PRK05113  111 IDEDNCIGCTKCIQACPVDAIV 132

FDH_b_like

cd10562

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...

131-179

2.79e-03

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.

Pssm-ID: 319884 [Multi-domain] Cd Length: 161 Bit Score: 37.28 E-value: 2.79e-03

                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1826627506 131 CEAICPAQAITIEAeeraDGSrrttrYDIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10562    78 CVKVCPTGALYKTE----NGA-----VVVDEDKCIGCGYCVAACPFDVP 117

PRK06991

electron transport complex subunit RsxB;

122-179

3.37e-03

electron transport complex subunit RsxB;

Pssm-ID: 235903 [Multi-domain] Cd Length: 270 Bit Score: 37.47 E-value: 3.37e-03

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICPAQAI--------TIEAEEradgsrrttrydidmtkCIYCGFCQEACPVDAI 179
Cdd:PRK06991   84 EQLCIGCTLCMQACPVDAIvgapkqmhTVLADL-----------------CTGCDLCVPPCPVDCI 132

oorD

PRK09626

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed

122-204

3.62e-03

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed

Pssm-ID: 236597 [Multi-domain] Cd Length: 103 Bit Score: 35.85 E-value: 3.62e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERAD-GSRRTTRYDidmTKCIYCGFCQEACPVDAI--VEGPNFEF------STETH 192
Cdd:PRK09626   15 ESRCKACDICVSVCPAGVLAMRIDPHAVlGKMIKVVHP---ESCIGCRECELHCPDFAIyvADRKEFKFaklskeAKERA 91

                          90
                  ....*....|..
gi 1826627506 193 EELLYNKEKLLD 204
Cdd:PRK09626   92 EAVKANKYMKLE 103

RDH

TIGR02486

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S ...

125-175

3.82e-03

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S cluster-containing reductive dehalogenases found primarily in halorespiring microorganisms such as dehalococcoides ethenogenes which contains as many as 17 enzymes of this type with varying substrate ranges. One example of a characterized species is the tetrachloroethene reductive dehalogenase (1.97.1.8) which also acts on trichloroethene converting it to dichloroethene.

Pssm-ID: 274158 Cd Length: 314 Bit Score: 37.41 E-value: 3.82e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 125 CIACKLCEAICPAQAITIEAEERADGSRRTTRYD----------IDMTKCI----------YCGFCQEACP 175
Cdd:TIGR02486 207 CETCGKCADECPSGAISKGGEPTWDPEDSNGDPPgennpglkwqYDGWRCLlfrcynegggGCGVCQAVCP 277

MtMvhB_like

cd10549

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...

122-143

4.01e-03

Pssm-ID: 319871 [Multi-domain] Cd Length: 128 Bit Score: 36.22 E-value: 4.01e-03

                          10        20
                  ....*....|....*....|..
gi 1826627506 122 EERCIACKLCEAICPAQAITIE 143
Cdd:cd10549   107 KEKCIGCGICAEVCPVNAIKLV 128

PRK00783

DNA-directed RNA polymerase subunit D; Provisional

122-191

4.21e-03

DNA-directed RNA polymerase subunit D; Provisional

Pssm-ID: 234837 [Multi-domain] Cd Length: 263 Bit Score: 37.17 E-value: 4.21e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEERADGsrrttrydiDMTKCIYCGFCQEACPVDAIVEG--PN-FEFSTET 191
Cdd:PRK00783  168 SEDCDECEKCVEACPRGVLELKEGKLVVT---------DLLNCSLCKLCERACPGKAIRVSddENkFIFTVES 231

NapF

COG1145

Ferredoxin [Energy production and conversion];

122-146

4.61e-03

Ferredoxin [Energy production and conversion];

Pssm-ID: 440760 [Multi-domain] Cd Length: 238 Bit Score: 37.39 E-value: 4.61e-03

                          10        20
                  ....*....|....*....|....*
gi 1826627506 122 EERCIACKLCEAICPAQAITIEAEE 146
Cdd:COG1145   212 PDKCIGCGACVKVCPVGAISLEPKE 236

RnfB

COG2878

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...

122-186

4.70e-03

Pssm-ID: 442125 [Multi-domain] Cd Length: 254 Bit Score: 37.28 E-value: 4.70e-03

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICPAQAITIEaEERADGSRRTTRYDIDMTKCIYC-GFCQEACPVDAIVEGPNFE 186
Cdd:COG2878   166 EDKCTGCGLCVEACPVDCIEMV-PVSPTVVVSSWDKGKAVRKVVGCiGLCCKKCCPAAAITVNNLA 230

CooF_like

cd10563

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...

114-180

5.80e-03

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.

Pssm-ID: 319885 [Multi-domain] Cd Length: 140 Bit Score: 36.08 E-value: 5.80e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1826627506 114 ALRRYP-SG-----EERCIACKLCEAICPAQAITIEAEERAdgsrrttrydidMTKCIYCGF-----CQEACPVDAIV 180
Cdd:cd10563    73 AMHKDPeTGivihdEEKCVGCWMCVMVCPYGAIRPDKERKV------------ALKCDLCPDretpaCVEACPTGALV 138

PRK06259

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional

103-175

6.58e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional

Pssm-ID: 235756 [Multi-domain] Cd Length: 486 Bit Score: 36.91 E-value: 6.58e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 103 GPLSPRFRGEHALRRYPSGEER------CIACKLCEAICPAQAIT-------------IEAEERADGSRRTTRYDIDMTK 163
Cdd:PRK06259  107 KSLRNYLQRKNEKITYPEDIEDikklrgCIECLSCVSTCPARKVSdypgptfmrqlarFAFDPRDEGDREKEAFDEGLYN 186

                          90
                  ....*....|..
gi 1826627506 164 CIYCGFCQEACP 175
Cdd:PRK06259  187 CTTCGKCVEVCP 198

porD

PRK09625

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed

123-175

6.74e-03

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed

Pssm-ID: 236596 [Multi-domain] Cd Length: 133 Bit Score: 35.49 E-value: 6.74e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 123 ERCIACKLCEAICPAQAItIEAEERADGsrrttrydIDMTKCIYCGFCQEACP 175
Cdd:PRK09625   59 EICINCFNCWVYCPDAAI-LSRDKKLKG--------VDYSHCKGCGVCVEVCP 102

HycB_like

cd10554

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...

126-179

6.78e-03

Pssm-ID: 319876 [Multi-domain] Cd Length: 149 Bit Score: 35.70 E-value: 6.78e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1826627506 126 IACKLCE-----AICPAQAITieaeeRADGSRRttrydIDMTKCIYCGFCQEACPVDAI 179
Cdd:cd10554    54 VQCRQCEdapcaNVCPVGAIS-----QEDGVVQ-----VDEERCIGCKLCVLACPFGAI 102

RNAP_D

cd07030

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is ...

112-191

7.05e-03

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits. RNAP is a large multi-subunit complex responsible for the synthesis of RNA. It is the principal enzyme of the transcription process, and is a final target in many regulatory pathways that control gene expression in all living cells. A single distinct RNAP complex is found in archaea, which may be responsible for the synthesis of all RNAs. The archaeal RNAP harbors homologues of all eukaryotic RNAP II subunits with two exceptions (RPB8 and RPB9). The 12 archaeal subunits are designated by letters and can be divided into three functional groups that are engaged in: (I) catalysis (A'/A", B'/B" or B); (II) assembly (L, N, D and P); and (III) auxiliary functions (F, E, H and K). The D subunit is equivalent to the RPB3 subunit of eukaryotic RNAP II. It contains two subdomains: one subdomain is similar the eukaryotic Rpb11/AC19/archaeal L subunit which is involved in dimerization, and the other is an inserted beta sheet subdomain. The assembly of the two largest archaeal RNAP subunits that provide most of the enzyme's catalytic functions depends on the presence of the archaeal D/L heterodimer.

Pssm-ID: 132908 [Multi-domain] Cd Length: 259 Bit Score: 36.48 E-value: 7.05e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1826627506 112 EHA---------LRRYPSGE--ERCIACKLCEAICPAQAITIEAEERADGsrrttrydiDMTKCIYCGFCQEACPVDAIV 180
Cdd:cd07030   147 EHAkwqpttacgYKYYPVIEidEDCDGCGKCVEECPRGVLELEEGKVVVE---------DLEDCSLCKLCERACDAGAIR 217

                          90
                  ....*....|....
gi 1826627506 181 EGP---NFEFSTET 191
Cdd:cd07030   218 VGWdedRFIFEVES 231

DMSOR_beta_like

cd16369

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

123-183

7.40e-03

Pssm-ID: 319891 [Multi-domain] Cd Length: 172 Bit Score: 36.21 E-value: 7.40e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 123 ERCIACKLCEAICpaqaitiEAEERADGSRRTTRYDID--------MTKCIYC--GFCQEACPVDAIVEGP 183
Cdd:cd16369     9 SRCIGCRACVAAC-------RECGTHRGKSMIHVDYIDrgestqtaPTVCMHCedPTCAEVCPADAIKVTE 72

QueG

COG1600

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...

122-175

8.32e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification

Pssm-ID: 441208 [Multi-domain] Cd Length: 345 Bit Score: 36.72 E-value: 8.32e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1826627506 122 EERCIACKLCEAICPAQAI---------------TIE------AEERAdgsrrttrydiDMTKCIY-CGFCQEACP 175
Cdd:COG1600   183 EDHCGSCTRCLDACPTGAIvapyvldarrcisylTIElkgpipEELRP-----------KMGNRIYgCDDCQDVCP 247

DMSOR_beta_like

cd16369

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...

125-175

9.37e-03

Pssm-ID: 319891 [Multi-domain] Cd Length: 172 Bit Score: 35.83 E-value: 9.37e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1826627506 125 CIACKL--CEAICPAQAITIEaeerADGSRRTTrydiDMTKCIYCGFCQEACP 175
Cdd:cd16369    51 CMHCEDptCAEVCPADAIKVT----EDGVVQSA----LKPRCIGCSNCVNACP 95

FDH_b_like

cd10562

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...

122-183

9.49e-03

Pssm-ID: 319884 [Multi-domain] Cd Length: 161 Bit Score: 35.74 E-value: 9.49e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1826627506 122 EERCIACKLCEAICPAQAItieaeeradgsrRTTRYDIDMTKCIYC------GF---CQEACPVDAIVEGP 183
Cdd:cd10562    99 EDKCIGCGYCVAACPFDVP------------RYDETTNKITKCTLCfdrienGMqpaCVKTCPTGALTFGD 157

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01