|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
45-1068 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 667.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 45 ITVSGIVTDGSGETLIGASVVQKGTTNASMTGLDGDYKLTVPSDATLVVTYVGFNPKEVQVNGKTKLDIVVSEDTKLLDE 124
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 125 VVVTALGIKRdKKSLGYALQEIKGDQLMETRDPNVANALAGKVAGLQIKQNGSGPAGSSRIVLRGNNSIGGNNQPLIVVD 204
Cdd:TIGR04056 81 VVVVGYGTQK-KKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 205 GVPIDNfsggtddlfnggidkgsGLSDIAPDDIESMSVLKGPAAAALYGSRAGNGVIMITTKKssGKKG-LGISYNTNFV 283
Cdd:TIGR04056 160 GVPRDN-----------------GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKR--GKEGkPKISYNAEFG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 284 IENPMQLPKYQNTYGQGLNGK-----YDVTASSSWGEKMTGQTVKDVIGRdaVYASYGNDLEDIMQTGTTWTNSIDISNS 358
Cdd:TIGR04056 221 FSTPTRLPEMLNAYEYAELYNeallnRGSSPPDIYTDEEIEAYRNGLDPD--LYPNTDWQDEIFKRTAFNQRHNLSVSGG 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 359 TDKGTFRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADNRikiGGDPDNIFYNYLLTPRSVHL 438
Cdd:TIGR04056 299 TEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNP---GGSTSNIWGALMLFPRGTPY 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 439 TDYKDqslYPNygfapntiatdgsginlsGLPASWVSNHGAMiRNPYWSMYKNTNSDKRNRLIGFGSLKYDFNDWLNIQG 518
Cdd:TIGR04056 376 STPPV---YSD------------------GYYPAYNSGNTSL-QNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKG 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 519 RYGMDYYASQYKNRQA----TNTPFWEKSGDYRITNESFYEINSDFLITATRDLsDKIGLVATGGGNIMYRRLNTertia 594
Cdd:TIGR04056 434 TFSYDYSNYKNKKYYKnpyyYNATGGANNGYYSESNSRSRNYYLEATLNYNRTF-GKHNVSALLGYSQQENKSSS----- 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 595 NGLVIPDF-FRMDNAKRATTEDRITRSQVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNRSFFYPSVGASWLITE-- 671
Cdd:TIGR04056 508 YGGLLDDLpSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEek 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 672 ---SLDKWdvnhsaINFAKLRVSWAQVGNSADAYQLLNERNISVTNITNTLTNQSESYFFSRFDETKRLYDLKNELVESY 748
Cdd:TIGR04056 588 fmkKLKKW------LSFLKLRASYGIVGNDNIGDRYPYLSLYNLGDGGYNFGTNNGTSVTGITESRYGNPNLKWEKTKKW 661
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 749 EIGLELKAFNNRLGLDFAFYNKDAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPVQTKDFQWSMDVNYSRNK 828
Cdd:TIGR04056 662 NLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNK 741
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 829 NTIVKLYPGVEQQIlnhvstrsLVEIVAKEGGSYGDIYGIPYLRND--------------NGDILIDD-SGLPIFDTN-K 892
Cdd:TIGR04056 742 NKILELDEGAYLPV--------KYPYISKEGGPIGQIYGYIADGLFkdddspkqtfgnvrPGDIKYKDvNGDGKIDDDdR 813
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 893 KKLGNSS-PLWMGGIVNYLTYKNFDVMFQIDMRYGGDVYMGsiargmGAGTLEGTLAGREGMTVEG--SRKSDNTANTtq 969
Cdd:TIGR04056 814 VPIGYSNtPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFND------GRGFYPFNGGDWGNVLKIVadNRWTPENPNA-- 885
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 970 ttaqeYWGRLGSG----------SEPWIYDATNIRFREFSVGYTIPRKALSKTPFQAIKLSLVGRNLFMIySKTKGFDPE 1039
Cdd:TIGR04056 886 -----DYPRLSYGdsnnsnnyqaSTRWLEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTF-SKYKGWDPE 959
|
1050 1060
....*....|....*....|....*....
gi 1821112816 1040 agftssnAQGIEFGSMPTLRSYGFNLNVS 1068
Cdd:TIGR04056 960 -------LQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
122-846 |
1.72e-46 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 177.71 E-value: 1.72e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 122 LDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALaGKVAGLQIKQNGsgpAGSSRIVLRGNNsiGGNNQPLI 201
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG---GGAGQISIRGFG--GGGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 202 VVDGVPIDNFSGGtddlfnggidkGSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLGISYNtn 281
Cdd:COG1629 75 LVDGVPLNDPSGG-----------DGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSAS-- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 282 fvienpmqlpkyqntygqglngkydvtassswgekmtgqtvkdvigrdavYASYGndledimqtgtTWTNSIDISNSTDK 361
Cdd:COG1629 141 --------------------------------------------------YGSYG-----------TYRASLSLSGGNGK 159
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 362 GTFRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADNrikiggdpDNIFYNYLLTPRSVHLTDY 441
Cdd:COG1629 160 LAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDS--------PGYLTLAALRPRGAMDDGT 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 442 kdqslypnygfapntiatdgsginlsglpaswvsnhgamirNPYwsmykNTNSDKRNRLIGFGSLKYD-FNDWLNIQGRY 520
Cdd:COG1629 232 -----------------------------------------NPY-----SNDTDDNTRDRYSLSLEYEhLGDGLKLSASA 265
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 521 gmdYYASQYKNRQATNTPFWEKSGDYRITNESFYEINSDFLITATRDLSDKIGLVAtgGGNIMYRRLNTERTIANGLvip 600
Cdd:COG1629 266 ---YYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLV--GLDYQRQDLDGSGYPLDLG--- 337
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 601 dffRMDNAKRATTEDRITRSQVNSLYATASFSYDNTLYLDLTARNDWSS----------TLNPDNRSF--FYPSVGASWL 668
Cdd:COG1629 338 ---SGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQ 414
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 669 ITESLdkwdvnhsainfaKLRVSWAQvGNSADAYQLLNERNISVTNITNTltnqsesyffsrfdetkrlyDLKNELVESY 748
Cdd:COG1629 415 LSPNL-------------SLYASYSR-GFRAPTFGELYANGTDPYSVGNP--------------------DLKPETSTNY 460
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 749 EIGLELKAFNNRLGLDFAFYNKDAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPVQtkdfQWSMDVNYSRNK 828
Cdd:COG1629 461 ELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTD 536
|
730
....*....|....*...
gi 1821112816 829 NTIVKLYPGVEQQILNHV 846
Cdd:COG1629 537 AKFDDDTDGSADLDGNRL 554
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
146-832 |
1.77e-21 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 100.22 E-value: 1.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 146 IKGDQLMETRDPNVANALAgKVAGLQIKQNGSGpaGSSRIVLRGnnsIGGNNQpLIVVDGVPIdNFSGGTddlfnggidK 225
Cdd:cd01347 5 ITAEDIEKQPATSLADLLR-RIPGVSVTRGGGG--GGSTISIRG---FGPDRT-LVLVDGLPL-ASSNYG---------R 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 226 GSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLGISYNTNfvienpmqlpkyQNTYGQGLNGKY 305
Cdd:cd01347 68 GVDLNTIPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTDEFGGSVTAGYG------------SDNSGSSGGGGF 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 306 DVTASSSWGEKMTGQTvkdvigrdavYASYgndledimQTGTTWTNSIDISNSTDkgtfrvgvmnlsnkgvvpnssFGRT 385
Cdd:cd01347 135 DVSGALADDGAFGARL----------YGAY--------RDGDGTIDGDGQADDSD---------------------EERY 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 386 SATIRGTAKLSDKFSVDAKLTYINQQADNRIkiggdpdnifynylltprsvhltdykdqslypnygfapntiatdgsgin 465
Cdd:cd01347 176 NVAGKLDWRPDDDTRLTLDAGYQDQDADGPG------------------------------------------------- 206
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 466 lSGLPASWVSNHGAMIRNPYWSMYKNTNSDKRNRLIGFGSLKYDFNDWlNIQGRYGmDYYASQYKNRQATNTPFWEKSGD 545
Cdd:cd01347 207 -GTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDT-GWTLRAN-LSYSYTDNDGDPLILNGGNNAAG 283
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 546 YRITNESFYEIN--SDFLITATRDLSDKIGLVA---TGGGNIMYRRLNTErtianglvipdffrmdnakrattedritrs 620
Cdd:cd01347 284 GDLGRSGYSSERdtTQLGFDAGLNAPFGTGPVAhtlTLGVEYRREELDEK------------------------------ 333
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 621 qVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNRSFFY----------PSVGASWLITESLdkwdvnhsainfaKLRV 690
Cdd:cd01347 334 -QTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTtakksyshwsPSLGLVYKLTDGL-------------SLYA 399
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 691 SWAQVGNSADAYQLLNERNISVTNITNTLtnqsesyffsrfdetkrlyDLKNELVESYEIGLELKaFNNRLGLDFAFYNK 770
Cdd:cd01347 400 SYSQGFRAPSLGELYGGGSHGGTAAVGNP-------------------NLKPEKSKQYELGLKYD-PGDGLTLSAALFRI 459
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1821112816 771 DAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPvqTKDFQWSMDVNYSRNKNTIV 832
Cdd:cd01347 460 DIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDL--TDGLGLTGSYTYTDTEVKRT 519
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
135-260 |
7.63e-18 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 80.01 E-value: 7.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 135 DKKSLGYALQEIKGDQLMETRDPNVANALAGkVAGLQIkqNGSGPAGSSRIVLRGNNSiggnNQPLIVVDGVPIDNFSGG 214
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSV--SSGGGGGGSSISIRGFGS----NRVLVLVDGVPLNSGGGG 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1821112816 215 tddlfnggidkGSGLSDIAPDDIESMSVLKGPaAAALYGSRAGNGV 260
Cdd:pfam07715 74 -----------SVDLNSIDPEDIERVEVLKGP-ASALYGSGAIGGV 107
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
115-288 |
6.72e-07 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 53.35 E-value: 6.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 115 VSEDTKLLDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALaGKVAGLQIKQNGSGPAGSSrivLRGNNSig 194
Cdd:PRK10064 23 VLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVL-KEVPGVQLTNEGDNRKGVS---IRGLDS-- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 195 gnNQPLIVVDGVPIDNfsggTDDLFNGgidKGSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGK--- 271
Cdd:PRK10064 97 --SYTLILIDGKRVNS----RNAVFRH---NDFDLNWIPVDAIERIEVVRGPMSS-LYGSDALGGVVNIITKKIGQKwhg 166
|
170 180
....*....|....*....|....*...
gi 1821112816 272 -----------KGLGISYNTNFVIENPM 288
Cdd:PRK10064 167 tvtvdttiqehRDRGDTYNGQFFTSGPL 194
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
45-1068 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 667.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 45 ITVSGIVTDGSGETLIGASVVQKGTTNASMTGLDGDYKLTVPSDATLVVTYVGFNPKEVQVNGKTKLDIVVSEDTKLLDE 124
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 125 VVVTALGIKRdKKSLGYALQEIKGDQLMETRDPNVANALAGKVAGLQIKQNGSGPAGSSRIVLRGNNSIGGNNQPLIVVD 204
Cdd:TIGR04056 81 VVVVGYGTQK-KKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVID 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 205 GVPIDNfsggtddlfnggidkgsGLSDIAPDDIESMSVLKGPAAAALYGSRAGNGVIMITTKKssGKKG-LGISYNTNFV 283
Cdd:TIGR04056 160 GVPRDN-----------------GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKR--GKEGkPKISYNAEFG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 284 IENPMQLPKYQNTYGQGLNGK-----YDVTASSSWGEKMTGQTVKDVIGRdaVYASYGNDLEDIMQTGTTWTNSIDISNS 358
Cdd:TIGR04056 221 FSTPTRLPEMLNAYEYAELYNeallnRGSSPPDIYTDEEIEAYRNGLDPD--LYPNTDWQDEIFKRTAFNQRHNLSVSGG 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 359 TDKGTFRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADNRikiGGDPDNIFYNYLLTPRSVHL 438
Cdd:TIGR04056 299 TEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNP---GGSTSNIWGALMLFPRGTPY 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 439 TDYKDqslYPNygfapntiatdgsginlsGLPASWVSNHGAMiRNPYWSMYKNTNSDKRNRLIGFGSLKYDFNDWLNIQG 518
Cdd:TIGR04056 376 STPPV---YSD------------------GYYPAYNSGNTSL-QNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKG 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 519 RYGMDYYASQYKNRQA----TNTPFWEKSGDYRITNESFYEINSDFLITATRDLsDKIGLVATGGGNIMYRRLNTertia 594
Cdd:TIGR04056 434 TFSYDYSNYKNKKYYKnpyyYNATGGANNGYYSESNSRSRNYYLEATLNYNRTF-GKHNVSALLGYSQQENKSSS----- 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 595 NGLVIPDF-FRMDNAKRATTEDRITRSQVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNRSFFYPSVGASWLITE-- 671
Cdd:TIGR04056 508 YGGLLDDLpSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEek 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 672 ---SLDKWdvnhsaINFAKLRVSWAQVGNSADAYQLLNERNISVTNITNTLTNQSESYFFSRFDETKRLYDLKNELVESY 748
Cdd:TIGR04056 588 fmkKLKKW------LSFLKLRASYGIVGNDNIGDRYPYLSLYNLGDGGYNFGTNNGTSVTGITESRYGNPNLKWEKTKKW 661
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 749 EIGLELKAFNNRLGLDFAFYNKDAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPVQTKDFQWSMDVNYSRNK 828
Cdd:TIGR04056 662 NLGLDLGFFNNRLSLTVDYYYKKTKDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNK 741
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 829 NTIVKLYPGVEQQIlnhvstrsLVEIVAKEGGSYGDIYGIPYLRND--------------NGDILIDD-SGLPIFDTN-K 892
Cdd:TIGR04056 742 NKILELDEGAYLPV--------KYPYISKEGGPIGQIYGYIADGLFkdddspkqtfgnvrPGDIKYKDvNGDGKIDDDdR 813
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 893 KKLGNSS-PLWMGGIVNYLTYKNFDVMFQIDMRYGGDVYMGsiargmGAGTLEGTLAGREGMTVEG--SRKSDNTANTtq 969
Cdd:TIGR04056 814 VPIGYSNtPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFND------GRGFYPFNGGDWGNVLKIVadNRWTPENPNA-- 885
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 970 ttaqeYWGRLGSG----------SEPWIYDATNIRFREFSVGYTIPRKALSKTPFQAIKLSLVGRNLFMIySKTKGFDPE 1039
Cdd:TIGR04056 886 -----DYPRLSYGdsnnsnnyqaSTRWLEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTF-SKYKGWDPE 959
|
1050 1060
....*....|....*....|....*....
gi 1821112816 1040 agftssnAQGIEFGSMPTLRSYGFNLNVS 1068
Cdd:TIGR04056 960 -------LQGNDGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
122-846 |
1.72e-46 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 177.71 E-value: 1.72e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 122 LDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALaGKVAGLQIKQNGsgpAGSSRIVLRGNNsiGGNNQPLI 201
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG---GGAGQISIRGFG--GGGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 202 VVDGVPIDNFSGGtddlfnggidkGSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLGISYNtn 281
Cdd:COG1629 75 LVDGVPLNDPSGG-----------DGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSAS-- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 282 fvienpmqlpkyqntygqglngkydvtassswgekmtgqtvkdvigrdavYASYGndledimqtgtTWTNSIDISNSTDK 361
Cdd:COG1629 141 --------------------------------------------------YGSYG-----------TYRASLSLSGGNGK 159
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 362 GTFRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADNrikiggdpDNIFYNYLLTPRSVHLTDY 441
Cdd:COG1629 160 LAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDS--------PGYLTLAALRPRGAMDDGT 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 442 kdqslypnygfapntiatdgsginlsglpaswvsnhgamirNPYwsmykNTNSDKRNRLIGFGSLKYD-FNDWLNIQGRY 520
Cdd:COG1629 232 -----------------------------------------NPY-----SNDTDDNTRDRYSLSLEYEhLGDGLKLSASA 265
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 521 gmdYYASQYKNRQATNTPFWEKSGDYRITNESFYEINSDFLITATRDLSDKIGLVAtgGGNIMYRRLNTERTIANGLvip 600
Cdd:COG1629 266 ---YYRYDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLV--GLDYQRQDLDGSGYPLDLG--- 337
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 601 dffRMDNAKRATTEDRITRSQVNSLYATASFSYDNTLYLDLTARNDWSS----------TLNPDNRSF--FYPSVGASWL 668
Cdd:COG1629 338 ---SGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSydvddtvtgtDSASGSRSYsaFSPSLGLTYQ 414
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 669 ITESLdkwdvnhsainfaKLRVSWAQvGNSADAYQLLNERNISVTNITNTltnqsesyffsrfdetkrlyDLKNELVESY 748
Cdd:COG1629 415 LSPNL-------------SLYASYSR-GFRAPTFGELYANGTDPYSVGNP--------------------DLKPETSTNY 460
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 749 EIGLELKAFNNRLGLDFAFYNKDAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPVQtkdfQWSMDVNYSRNK 828
Cdd:COG1629 461 ELGLRYRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTD 536
|
730
....*....|....*...
gi 1821112816 829 NTIVKLYPGVEQQILNHV 846
Cdd:COG1629 537 AKFDDDTDGSADLDGNRL 554
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
116-830 |
4.00e-43 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 167.34 E-value: 4.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 116 SEDTKLLDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALAgKVAGLQIkQNGSGPAGSSRIVLRGnnsiGG 195
Cdd:COG4771 21 AEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSV-TRSGGRGGSSGISIRG----LG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 196 NNQPLIVVDGVPIDNFSGGTddlfnggidkGSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLG 275
Cdd:COG4771 95 GDRVLVLIDGVPVNNPALGG----------GGDLSYIPPDDIERIEVIRGPASA-LYGSDAIGGVINIITKKPTDELEGS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 276 ISYNtnfvienpmqlpkyqntYGQGLNGKYDVTASSSW-GEKMTGQtvkdvigrdaVYASYGNdledimqtgttwtnsid 354
Cdd:COG4771 164 VSLG-----------------YGSNGNGTYSGSLSLGGpGDKLSFL----------LSGSYRD----------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 355 isnstdkgtfRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADNRIKIGGDPDNIFYNYLLTPR 434
Cdd:COG4771 200 ----------RDGYLDYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDT 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 435 SVHLTDYkdqslypnygfapntiatdgsginlsglpaswvsnhgamirnpywsmykntnsdkrnrligFGSLKYDFNDWL 514
Cdd:COG4771 270 TTDRGNY-------------------------------------------------------------SLRYNGDLGDNL 288
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 515 NIQGRYgmdyyasQYKNRQATNTPFWEKSGDYRITNESFYEINSDFlitaTRDLSDKIGLVAtgGGNIMYRRLNTERTIA 594
Cdd:COG4771 289 DLSLYY-------SRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDL----TYPLGGNHTLTL--GAEYRYDDLDSSSFLG 355
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 595 NglvipdffrmdnakrattedRITRSQVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNRSFFYPSVGASWLITESLd 674
Cdd:COG4771 356 G--------------------ADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYDLSDNL- 414
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 675 kwdvnhsainfaKLRVSWAQVGNSADAYQLLNerNISVTNITNTLTNQsesyffsrfdetkrlyDLKNELVESYEIGLEL 754
Cdd:COG4771 415 ------------TLRASYGRGFRAPSLAELYG--SGTGTPGRYVLGNP----------------DLKPETSDNYELGLEY 464
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1821112816 755 KAFNNRLGLDFAFYNKDAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPvqTKDFQWSMDVNYSRNKNT 830
Cdd:COG4771 465 RLGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQYENVGKARTYGLELELKYRL--GKGLTLTASYTYLDSKID 538
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
125-280 |
7.60e-36 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 137.31 E-value: 7.60e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 125 VVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALAgKVAGLQIKQNGsGPAGSSRIVLRGNNSiggnNQPLIVVD 204
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQVSSSG-GPGSAASISIRGLGS----NQTLVLID 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1821112816 205 GVPIDNFSGGTDDLfnggidkgsglSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLGISYNT 280
Cdd:COG4206 75 GVPLNDPSLGGVDL-----------SLIPPDDIERIEVLKGAASA-LYGSDAIGGVINITTKKGKKGFKGSVSASY 138
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
146-832 |
1.77e-21 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 100.22 E-value: 1.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 146 IKGDQLMETRDPNVANALAgKVAGLQIKQNGSGpaGSSRIVLRGnnsIGGNNQpLIVVDGVPIdNFSGGTddlfnggidK 225
Cdd:cd01347 5 ITAEDIEKQPATSLADLLR-RIPGVSVTRGGGG--GGSTISIRG---FGPDRT-LVLVDGLPL-ASSNYG---------R 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 226 GSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKKGLGISYNTNfvienpmqlpkyQNTYGQGLNGKY 305
Cdd:cd01347 68 GVDLNTIPPELIERVEVLKGPSSA-LYGSGAIGGVVNIITKRPTDEFGGSVTAGYG------------SDNSGSSGGGGF 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 306 DVTASSSWGEKMTGQTvkdvigrdavYASYgndledimQTGTTWTNSIDISNSTDkgtfrvgvmnlsnkgvvpnssFGRT 385
Cdd:cd01347 135 DVSGALADDGAFGARL----------YGAY--------RDGDGTIDGDGQADDSD---------------------EERY 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 386 SATIRGTAKLSDKFSVDAKLTYINQQADNRIkiggdpdnifynylltprsvhltdykdqslypnygfapntiatdgsgin 465
Cdd:cd01347 176 NVAGKLDWRPDDDTRLTLDAGYQDQDADGPG------------------------------------------------- 206
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 466 lSGLPASWVSNHGAMIRNPYWSMYKNTNSDKRNRLIGFGSLKYDFNDWlNIQGRYGmDYYASQYKNRQATNTPFWEKSGD 545
Cdd:cd01347 207 -GTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLNDT-GWTLRAN-LSYSYTDNDGDPLILNGGNNAAG 283
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 546 YRITNESFYEIN--SDFLITATRDLSDKIGLVA---TGGGNIMYRRLNTErtianglvipdffrmdnakrattedritrs 620
Cdd:cd01347 284 GDLGRSGYSSERdtTQLGFDAGLNAPFGTGPVAhtlTLGVEYRREELDEK------------------------------ 333
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 621 qVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNRSFFY----------PSVGASWLITESLdkwdvnhsainfaKLRV 690
Cdd:cd01347 334 -QTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTtakksyshwsPSLGLVYKLTDGL-------------SLYA 399
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 691 SWAQVGNSADAYQLLNERNISVTNITNTLtnqsesyffsrfdetkrlyDLKNELVESYEIGLELKaFNNRLGLDFAFYNK 770
Cdd:cd01347 400 SYSQGFRAPSLGELYGGGSHGGTAAVGNP-------------------NLKPEKSKQYELGLKYD-PGDGLTLSAALFRI 459
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1821112816 771 DAKDQILKMNIPASSGFTYKYINAGNVRNRGIELVLSGTPvqTKDFQWSMDVNYSRNKNTIV 832
Cdd:cd01347 460 DIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDL--TDGLGLTGSYTYTDTEVKRT 519
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
135-260 |
7.63e-18 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 80.01 E-value: 7.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 135 DKKSLGYALQEIKGDQLMETRDPNVANALAGkVAGLQIkqNGSGPAGSSRIVLRGNNSiggnNQPLIVVDGVPIDNFSGG 214
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSV--SSGGGGGGSSISIRGFGS----NRVLVLVDGVPLNSGGGG 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1821112816 215 tddlfnggidkGSGLSDIAPDDIESMSVLKGPaAAALYGSRAGNGV 260
Cdd:pfam07715 74 -----------SVDLNSIDPEDIERVEVLKGP-ASALYGSGAIGGV 107
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
440-810 |
9.33e-17 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 84.44 E-value: 9.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 440 DYKDQSLYPNYGFAPNTIATDGSGINLSGLPASWVSNHGAMIRNPYWSMYKNTNSDKRNRLIGFGSLKYDFNDWLNIQGR 519
Cdd:pfam00593 1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLST 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 520 YGMDYYASQYKNRQATNTPFWEKSGDYRITNESFYEINSDFLITATRDLSDKIGL-VATGGGNIMYRRLNTERTIANGLV 598
Cdd:pfam00593 81 LRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLgVELRTAGLDYRRLDDDAYDPYDPA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 599 IPDFFRMDNAKRATTedritrsqvnSLYATASFSYDNTLYLDLTARNDWSSTLNPDNR----------SFFYPSVGASWL 668
Cdd:pfam00593 161 NPSSSSYSDTTTDSY----------GLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNgggdnfsrsySAFSPRLGLVYK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 669 ITESLdkwdvnhsainfaKLRVSWAQVGNSADAYQLLNERNISVTNITNTLTNqsesyffsrfdetkrlyDLKNELVESY 748
Cdd:pfam00593 231 PTDNL-------------SLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGNP-----------------DLKPETSDNY 280
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1821112816 749 EIGLELkaFNNRLGLDFAFYNKDAKDQILKM-NIPASSGFTYKYINAGNVRNRGIELVLSGTP 810
Cdd:pfam00593 281 ELGLKY--DDGRLSLSLALFYIDIKNLITSDpDGPGLGGTVYTYTNVGKARIRGVELELSGRL 341
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
47-127 |
1.30e-15 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 73.01 E-value: 1.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 47 VSGIVTD-GSGETLIGASVVQKGTTNASMTGLDGDYKLTVPS--DATLVVTYVGFNPKEVQV---NGKTK-LDIVVSEDT 119
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTKGTVTDADGNFELKNLPagTYTLVVSFVGYKTQEKKVtvsNDNTLdVNFLLKEDA 80
|
....*...
gi 1821112816 120 KLLDEVVV 127
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
236-266 |
2.57e-12 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 61.83 E-value: 2.57e-12
10 20 30
....*....|....*....|....*....|.
gi 1821112816 236 DIESMSVLKGPAAAALYGSRAGNGVIMITTK 266
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
89-833 |
4.76e-12 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 70.31 E-value: 4.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 89 ATLVVTYVGFNPKEVQvngkTKLDIVVSEDTKLLDEVVVTAlgikRDKKSLGYALQEI----KGD--------------- 149
Cdd:COG4773 3 ALLAGSGLAAAAAGAL----AQAAAAAAAEATTLPEVTVTG----TAEGTGGYTAKSSstatKLDtplretpqsvsvvtr 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 150 QLMETRDP-NVANALAgKVAGLQIKQNGSGpaGSSRIVLRGnnsIGGNNqplIVVDGVPIDNFSGGTDDLFNggidkgsg 228
Cdd:COG4773 75 QLIEDQGAtTLDDALR-NVPGVTVSSYDGG--GRDSFSIRG---FSIDN---YLRDGLPLGGFGGGQPDTAN-------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 229 lsdiapddIESMSVLKGPAAAaLYGsrAGN--GVIMITTKKssgkkglgisyntnfvienpmqlPKYQNtygqglngKYD 306
Cdd:COG4773 138 --------LERVEVLKGPAGL-LYG--AGSpgGLVNLVTKR-----------------------PTAEP--------QGE 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 307 VTASsswgekmtgqtvkdvigrdavYASYGndledimqtgtTWTNSIDISNS-TDKGTF--RVGVMNLSNKGVVPNSSFG 383
Cdd:COG4773 176 VSLS---------------------AGSWD-----------TYRATADVGGPlNEDGTLryRLNAAYEDGDSFRDGVDNR 223
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 384 RTSATIRGTAKLSDKFSVDAKLTYINQQADnrikiggdpdnifynylltprsvhltdykdqslyPNYGFAPntiaTDGSG 463
Cdd:COG4773 224 RTLIAPSLDWDLTDDTTLTLGAEYQDDDST----------------------------------GDRGFLP----LDGTL 265
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 464 INLsglPASWVSNhgamirnPYWSMYKNTNsdkrnrLIGFGSLKYDFNDWLNIQGRYGMDYYASQYKNRQATNTPFwEKS 543
Cdd:COG4773 266 LDL---PRSTNLG-------EPWDYYDTET------TTLFAELEHRFNDDWSLRANARYSDSDRDGRSAYAYGAPD-AAT 328
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 544 GDYRITNESFYEINSDFLITAtrDLSdkiGLVATGG------GNIMYRRLNTERTIANGLVI----PDFFRMDNAKRATT 613
Cdd:COG4773 329 GTLTRYASARDGDSRSDSLDA--NLN---GKFETGGlehtllVGADYSRYDSDSDSATAGTIniynPVYGNLPEPDFDAS 403
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 614 EDRITRSQvNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNR---------SFFYPSVGASWLITEsldkwdvNHSain 684
Cdd:COG4773 404 DTDTTTRQ-TGLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLggsttsyddSAFTPRAGLVYDLTP-------GLS--- 472
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 685 fakLRVSWAQvgnsadayqllnernisvtnitnTLTNQSESYFFSRFdetkrlydLKNELVESYEIGLELKAFNNRLGLD 764
Cdd:COG4773 473 ---LYASYSE-----------------------SFEPQSGADNNGNP--------LDPETGKQYEAGVKGELFDGRLNAT 518
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 765 FAFYnkdakdQILKMNIPASSGF-TYKYINAGNVRNRGIELVLSGTPVQtkdfQWSMDVNYSRNKNTIVK 833
Cdd:COG4773 519 LAVF------DITQKNVATTDPDnPNFYVQVGEVRSRGVELELSGELTP----GLNLIAGYTYTDAKITK 578
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
117-825 |
1.30e-10 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 65.33 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 117 EDTKLLDEVVVTALGIKRDK-KSLGYALQEIKGDQLMETRDPNVANALAgKVAGLQIKQN------------GSGPAGSS 183
Cdd:COG4772 18 EAATTLETVVVTGSRAAEARlKDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEEdgfglrpnigirGLGPRRSR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 184 RIVLRgnnsiggnnqplivVDGVPI--DNFSGGTDDLFNggidkgsglsdiAPDDIESMSVLKGPAAAaLYGSRAGNGVI 261
Cdd:COG4772 97 GITLL--------------EDGIPIapAPYGDPAAYYFP------------DLERMERIEVLRGAAAL-RYGPQTVGGAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 262 mittkkssgkkglgisyntNFVIENPMQLPKYQ--NTYGQglNGKYDVTASSSwgekmtgqtvkDVIGRDAVYASYgndl 339
Cdd:COG4772 150 -------------------NFVTRTIPTAFGGElrVTGGS--FGYRRTHASVG-----------GTVGNFGYLVEY---- 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 340 edimqtgttwtnsidiSNSTDKGtFRvgvmnlsnkgvvPNSSFGRTSATIRGTAKLSDKFSVDAKLTYINQQADnrikig 419
Cdd:COG4772 194 ----------------SRKRGDG-FR------------DNSGFDINDFNAKLGYRLSDRQELTLKFQYYDEDAN------ 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 420 gdpdnifynyllTPRSVHLTDYKD---QSLYPNygfapNTIATDGSGINLSglpaswvsnhgamirnpywsmYKNTNSDK 496
Cdd:COG4772 239 ------------TPGGLTDAQFDAdprQSYRPA-----DQFDTRRTQLSLR---------------------YEHQLSDN 280
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 497 RN-RLIGFGSlkyDFN-DWLNIQGRYGMDYYASQYKNRqatntpfwekSGDYR-ITNESFYEINSDFLitatrdlsdKIG 573
Cdd:COG4772 281 TTlTTTAYYN---DFSrNWYIRQNTADPNTPGLGLRGN----------PRGYRsYGIEPRLTHRFELG---------GVP 338
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 574 LVATGGGNimYRRLNTERtiangLVIPDFFRMDNAKRATTEDRITRSQVNSLYATASFSYDNTL---------YLDLTAR 644
Cdd:COG4772 339 HTLEVGLR--YHREEEDR-----KQYVNTYGQGRSGAGLRRDRRFSADALAAYAQNRFELTGRLtltpglryeHIRRDRT 411
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 645 NDWSSTLNPD-----NRSFFYPSVGASWLITESLdkwdvnhsainfaklrvswaqvgnsadayqllnernisvtnitNTL 719
Cdd:COG4772 412 DRYSTRTGGDdsgsnSYSEFLPGLGLLYQLTDNL-------------------------------------------QLY 448
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 720 TNQSESY----FFSRFDETKRLYDLKNELVESYEIGLELKAfNNRLGLDFAFYNKDAKDQILkmNIPASSGFTYKYINAG 795
Cdd:COG4772 449 ANVSRGFepptFGDLAYGNGGNPDLKPEKSWNYELGTRGRI-GNGLSAEVALFYIDYDNELG--SCSAAGGDRSTFTNAG 525
|
730 740 750
....*....|....*....|....*....|
gi 1821112816 796 NVRNRGIELVLSGTPVQTKDFQWSMDVNYS 825
Cdd:COG4772 526 ETRHQGLELALDYDLLKGGGLGLPLFAAYT 555
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
150-833 |
2.93e-09 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 61.05 E-value: 2.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 150 QLMETRDP-NVANALAGkVAGLQIKQNGSGpaGSSRIVLRGNNSIGGnnqplIVVDGVPIDnfSGGTDDLFNggidkgsg 228
Cdd:COG4774 19 ELIEDQGAtSLADALRN-VPGVTFGAGEGG--NGDSFSIRGFSASGD-----IYVDGLRDP--GQYRRDTFN-------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 229 lsdiapddIESMSVLKGPAAAaLYGSRAGNGVIMITTKKssgkkglgisyntnfvienpmqlPKYQNtygqglngKYDVT 308
Cdd:COG4774 81 --------LERVEVLKGPASV-LYGRGSPGGVINLVTKR-----------------------PTDEP--------FTEVT 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 309 ASsswgekmtgqtvkdvigrdavYASYGndledimqtgtTWTNSIDISNSTDKGT-FRVGVMNLSNKGVVPNSSFGRTSA 387
Cdd:COG4774 121 LT---------------------YGSDG-----------QRRATLDVNGPLGDDLaYRLNGMYRDSDSYRDGVDNDRWGI 168
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 388 TIRGTAKLSDKFSVDAKLTYINqqaDNRIKIGGDPDNIFYNYLLTPRSVhltdykdqslypNYGFApntiatdgsginls 467
Cdd:COG4774 169 APSLTWRLGDRTRLTLDYEYQD---DDRTPDYGVPAVANGRPVDVDRST------------FYGQP-------------- 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 468 glpaswvsnhgamirnpywsmyknTNSDKRNRLIGFGSLKYDFNDWLNIQGRYGMDYYASQYKNRQATNTPfweKSGDYR 547
Cdd:COG4774 220 ------------------------DDYSDSETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRNTYPTGGN---ATGTVT 272
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 548 ItneSFYEINSDFLITATR-DLSdkiGLVATG--------GGNIMYRRLNTERTIANGLVI------PDFFRMDNAKRAT 612
Cdd:COG4774 273 R---SAYRRDQDNDTLSNQtDLT---GKFDTGgvkhtllaGVEYSREDSDNARYSGGGTAPtvnlynPVYGAPVTGPTLG 346
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 613 TEDRITRSQVNSLYATASFSYDNTLYLDLTARNDWSSTLNPDNR----------SFFYPSVGASWLITEsldkwdvnhsa 682
Cdd:COG4774 347 GADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTtgattssyddSAFSPRAGLVYKPTP----------- 415
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 683 infaklrvswaqvgnsadayqllnerNISV-TNITNTLTNQSESYFFSRFDEtkrlyDLKNELVESYEIGLELKAFNNRL 761
Cdd:COG4774 416 --------------------------NLSLyASYSTSFNPGGGAPSLSNAGQ-----ALDPEKSRQYEVGVKWDLLDGRL 464
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1821112816 762 GLDFAFYnkdakdQILKMNI----PASSGFtykYINAGNVRNRGIELVLSGTPVQtkdfQWSMDVNYSRNKNTIVK 833
Cdd:COG4774 465 SLTAALF------RIEKTNVrttdPANPGV---YVQTGEQRSRGVELEATGELTP----GWSVLAGYTYLDAEITK 527
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
122-830 |
7.14e-09 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 59.71 E-value: 7.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 122 LDEVVVTALGIKRDKKSLGYALQEIKGDQLmETRDPNVANALAGKVAGLQIKQNGSGPAGSsrIVLRGNnsigGNNQPLI 201
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQI-ESKQANNLADALNTVPGVDVTGGGRPPGQS--INIRGL----QDNRVLV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 202 VVDGVPidnfSGGTDDLFNGGIdkgsglSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGKkglgisyntn 281
Cdd:TIGR01785 74 VVDGAR----QNYQRGGAHNGS------LFVDPELLKRIEIVKGPSSS-LYGSGALGGVVAFRTKDAADL---------- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 282 fvienpmqLPKYQNTYGQgLNGKYDvTASSSWGekmtgqtvkdviGRDAVYASYGNDLEDIMQTGTTwtnsidisnstDK 361
Cdd:TIGR01785 133 --------LRPGQLFGGL-AKLSYG-SNNNSFG------------GSVAVAGRLDDNLDALVAATYR-----------DG 179
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 362 GTFRVGvmnlsNKGVVPNSSFGRTSATIRGTAKLSDKFSVdaKLTYINQQADNRIKiggdpdnifynylltprsvhltdy 441
Cdd:TIGR01785 180 GNYRNG-----NKEEATNSAYVQKNLLAKLGWQLDDAQRL--EFSYFTTEGSLDEA------------------------ 228
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 442 kdQSLYPNYGFAPNTIatdgsginlsglpaswvsnhgamirnpyWSMYkntNSDKRNRLIgfgSLKYDFNDwlniQGRYG 521
Cdd:TIGR01785 229 --QNSGPGTEYVLGSS----------------------------STLL---ASSTRDRSA---TLTYNWTP----EDNPW 268
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 522 MDYYASQYKNRqatnTPFWE-KSGDYRITNESFYEINSDFLITATRDLSDKIGLVATGGGNIMYRRLNTERtianglvip 600
Cdd:TIGR01785 269 LDATASLYYNR----TENDNdRSARGVGREEGYQYTTYGATLQNTSRFDVASWSTLTYGVDWMKDKRRTES--------- 335
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 601 dfFRMDNAKRATTEDRITRSQVNSLYATASFSYDNTLY-LDLTARNDWSSTlNPDN----------RSFFYPSVGASWLI 669
Cdd:TIGR01785 336 --FDPNSVTTIVPNPPSAKEYFFGLFLQDNIPLLDDRLtLSAGLRYDHYKL-SPKTtadteavdrsYSRWSPSLGLSYKP 412
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 670 TESLDkwdvnhsainfakLRVSWAQvGNSADAYqllNERNISVTNITNTLTNqsesyffsrfdETKRLYDLKNELVESYE 749
Cdd:TIGR01785 413 VDWLT-------------LYASYSQ-GFRAPSI---DELYGTGDHPGTPGGY-----------TFAPNPNLKPETSKTWE 464
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 750 IGLELK-----AFNNRLGLDFAFYNKDAKDQILKM-----NIPASSGFTYKYINAGNVRNRGIELVLSgtpVQTKDFQWS 819
Cdd:TIGR01785 465 LGANLSfdnllLDNDQLQFKVAYFYNDVKDFIDLTigvtdNVTAGMNNITQYVNIDGARIRGIEASAS---YDAGLWATG 541
|
730
....*....|.
gi 1821112816 820 MDVNYSRNKNT 830
Cdd:TIGR01785 542 LSYGYTIGKDQ 552
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
46-114 |
2.58e-07 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 49.20 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 46 TVSGIVTDGSGETLIGASVV----QKGTTNASMTGLDGDYKLT--VPSDATLVVTYVGFNPKE-----VQVNGKTKLDIV 114
Cdd:pfam13620 1 TISGTVTDPSGAPVPGATVTvtntDTGTVRTTTTDADGRYRFPglPPGTYTVTVSAPGFKTATrtgvtVTAGQTTTLDVT 80
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
115-288 |
6.72e-07 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 53.35 E-value: 6.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 115 VSEDTKLLDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALaGKVAGLQIKQNGSGPAGSSrivLRGNNSig 194
Cdd:PRK10064 23 VLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVL-KEVPGVQLTNEGDNRKGVS---IRGLDS-- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 195 gnNQPLIVVDGVPIDNfsggTDDLFNGgidKGSGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGK--- 271
Cdd:PRK10064 97 --SYTLILIDGKRVNS----RNAVFRH---NDFDLNWIPVDAIERIEVVRGPMSS-LYGSDALGGVVNIITKKIGQKwhg 166
|
170 180
....*....|....*....|....*...
gi 1821112816 272 -----------KGLGISYNTNFVIENPM 288
Cdd:PRK10064 167 tvtvdttiqehRDRGDTYNGQFFTSGPL 194
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
123-271 |
9.82e-06 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 49.64 E-value: 9.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 123 DEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALAGkVAGLQIkQNGSGPAGSSRIVLRGNNSiggnNQPLIV 202
Cdd:PRK13486 26 DVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDV-ESGTGKTGGLEISIRGMPA----SYTLIL 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 203 VDGVPidnfSGGTDDLFNGGIdKGSGLSDIAP-DDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSSGK 271
Cdd:PRK13486 100 IDGVR----QGGSSDVTPNGF-SAMNTGFMPPlAAIERIEVIRGPMST-LYGSDAMGGVVNIITRKNADK 163
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
116-331 |
1.58e-05 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 48.98 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 116 SEDTKLLDEVVVTALGIKRDKKSLGYAL---QEIKgdqlmetRDPNVaNALAG---KVAGLQIKQN-GSGPAGSSR-IVL 187
Cdd:PRK13528 28 SSDDDNGETMVVEATAEQELKQQPGVSIitaEDIK-------KRPPV-NDLSDiirKMPGVNLTGNsASGTRGNNRqIDI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 188 RGnnsIGGNNQpLIVVDGVPIDN-----FSggtddlFNGGIDKGSGLSDIAPDDIESMSVLKGPAAAAlYGSRAGNGVIM 262
Cdd:PRK13528 100 RG---MGPENT-LILIDGVPVTSrnsvrYS------WRGERDTRGDTNWVPPEMVERIEVIRGPAAAR-YGSGAAGGVVN 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 263 ITTKKSSGKKGLGISYNTN--------------FVIENPMQlpkyQNTYGQGLNGKYDVTASSSWGEKmTGQTVKDVIGR 328
Cdd:PRK13528 169 IITKRPTNDWHGSLSLYTNqpesskegatrranFSLSGPLA----GDALTMRLYGNLNKTDADSWDIN-SSAGTKNAAGR 243
|
...
gi 1821112816 329 DAV 331
Cdd:PRK13528 244 EGV 246
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
116-310 |
2.81e-05 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 48.08 E-value: 2.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 116 SEDTKLlDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALAGkVAGLQIKQNGSGPagssRIVLRGnnsIGG 195
Cdd:PRK13484 25 SSDKKE-DTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKD-VEGISITGGNEKP----DISIRG---LSG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 196 NnQPLIVVDGVPID------NFSGGtddlFNGGIdkgsglsdIAP-DDIESMSVLKGPAAAaLYGSRAGNGVIMITTKKS 268
Cdd:PRK13484 96 D-YTLILVDGRRQSgresrpNGSGG----FEAGF--------IPPvEAIERIEVIRGPMSS-LYGSDAIGGVINIITKPV 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1821112816 269 S-----GKKGLG--ISYNTNF-------------VIENPMQLPKYQN---------TYGQGLNGKYDVTAS 310
Cdd:PRK13484 162 NnqtwdGVLGLGgiIQEHGKFgnsttndfylsgpLIKDKLGLQLYGGmnyrkedsiSQGTPAKDNKNITAT 232
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
186-830 |
4.46e-05 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 47.41 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 186 VLRGNNSiGGNNQPLIVVDGVPIDNFSGGTddLFNGGIDKG-SGLSDIAPDDIESMSVLKGPAAAaLYGSRAGNGVIMIT 264
Cdd:TIGR01783 32 VVVGGSG-GTTQFGNITIRGFGLEVDIDNV--YLDGVPLLSrGNLAIVDPAMVERVEVLRGPASL-LYGGSAPGGVINIV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 265 TKKssgkkglgisyntnfvienPMQLPKYqntygqglngkyDVTASssWGEKMTGQTVKDVigrdavYASYGNDledimq 344
Cdd:TIGR01783 108 TKR-------------------PQDEPKG------------SVTFG--AGTRSGYRTAFDL------GGPLGAD------ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 345 tgttwtNSIDisnstdkgtFRVGVMNLSNKGVVPNSSFGRTSATIRGTAKLSDKfsvdAKLTYInqqadnrikiggdpdn 424
Cdd:TIGR01783 143 ------GTFR---------GRLNGARQDGDSFYDGAGEETRLGATATDWQLDDR----TLLRLG---------------- 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 425 ifynylltprsVHLTDYKDQSLYPNYGFAPNTIATDGSGINLSGLPASWvsnhgamirnpywsmykntNSDKRNRLIGFG 504
Cdd:TIGR01783 188 -----------AYYQKERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNR-------------------NYDDREYLSYGL 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 505 SLKYDFNDwlNIQGRYGMDYYASQYKNRQATNTPFWEKSGDYRItnesfYEINSDFLITATRDLSDKIGLVATGGGNIM- 583
Cdd:TIGR01783 238 SLEYQFND--VWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGR-----SLTVVNVKQDRVQIDAGLDGEFETGPIEHDl 310
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 584 -----YRRLNTERTIANGLVIPDFFRMDNAKRATT------EDRITRSQV---NSLYATASFSYDNTL------YLDLTA 643
Cdd:TIGR01783 311 llgvsYGQRTTNRFNNTGYPSDNIYSLTATSSARTdigdspKDRALSSTTkalNGVALQRILLADKWTltlggrYDSVDV 390
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 644 RNDWSSTLNPDNRSFFY--PSVGASWLITeslDKWDVNhsainfaklrvswaqvGNSADAYQLLNERNISVTNItntltn 721
Cdd:TIGR01783 391 KSNNGVAGSTGKRDDSQftPSLGVAYKPT---DDWSLY----------------ASYAESFKPGGYYPKGAGNS------ 445
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 722 qsesyffsrfdetkrLYDLKNELVESYEIGLELKaFNNRLGLDFAFYNKDAKDQIlkMNIPASSGFtykYINAGNVRNRG 801
Cdd:TIGR01783 446 ---------------GDILEPEKGKNYELGVRYD-LGDSLLATAALFRITKDNQL--VQDPVNGTF---SVNAGKTRNRG 504
|
650 660
....*....|....*....|....*....
gi 1821112816 802 IELVLSGTPvqTKDFQWSMDVNYSRNKNT 830
Cdd:TIGR01783 505 VELEARGYL--TPGLSLSAGYTYTDAEFT 531
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
177-271 |
2.66e-04 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 45.02 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 177 SGPAGSSR-IVLRGnnsIGGNNQpLIVVDGVPI---DNFSGGtddlFNGGIDKGSGLSDIAPDDIESMSVLKGPAAAAlY 252
Cdd:PRK13524 90 SGQRGNNRqIDIRG---MGPENT-LILIDGKPVssrNSVRYG----WRGERDTRGDTNWVPPEMIERIEVLRGPAAAR-Y 160
|
90
....*....|....*....
gi 1821112816 253 GSRAGNGVIMITTKKSSGK 271
Cdd:PRK13524 161 GNGAAGGVVNIITKKPTGE 179
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
169-277 |
5.47e-04 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 43.83 E-value: 5.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 169 GLQIKQNGsGPAGSSRIVLRGNNSiggnNQPLIVVDGVPidnfsggtddLFNGGIDKGSGLSDIAPDDIESMSVLKGPAA 248
Cdd:PRK10641 71 GVDIAQNG-GLGQLSSLFIRGTNS----SHVLVLIDGVR----------LNQAGISGSADLSQIPISLVQRIEYIRGPRS 135
|
90 100
....*....|....*....|....*....
gi 1821112816 249 AaLYGSRAGNGVIMITTKksSGKKGLGIS 277
Cdd:PRK10641 136 A-VYGSDAIGGVVNIITT--RDKPGTTLS 161
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
122-269 |
1.02e-03 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 43.22 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 122 LDEVVVTALGIKRDKKSLGYALQEIKGDQLMETRDPNVANALAgKVAGLQIKQNGSgpagSSRIVLRGNNSiggnNQPLI 201
Cdd:PRK13513 35 TDTMVVTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALK-DVPGVVVTGGGS----TSDISIRGMAA----KYTLI 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1821112816 202 VVDGVPIDnfSGGT---DDlfNGGIDKGsGLSDIAPddIESMSVLKGPAAAaLYGSRAGNGVIMITTKKSS 269
Cdd:PRK13513 106 LVDGKRVD--TRSTrpnSD--GSGIEQG-WLPPLAA--IERIEVVRGPMSS-LYGSDAMGGVINIITRKVQ 168
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
47-105 |
2.29e-03 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 37.89 E-value: 2.29e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1821112816 47 VSGIVTDGSGETLIGASVVQKGTTNASMTGLDGDY-KLTVPSDATLVVTYVGFNPKEVQV 105
Cdd:cd11308 2 IKGFVTDATGNPIANATISVEGINHDVTTAKDGDYwRLLLPGTYNVTASAPGYQPVTKTV 61
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