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Conserved domains on  [gi|1814777838|ref|XP_032473984|]
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zona pellucida-binding protein 2 isoform X1 [Phocoena sinus]

Protein Classification

Sp38 domain-containing protein( domain architecture ID 10538336)

Sp38 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sp38 pfam07354
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 149-326 1.60e-107

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


:

Pssm-ID: 336682  Cd Length: 177  Bit Score: 311.04  E-value: 1.60e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 149 FTTKSCVGKYNDLLFRLLKKILDNLISDLSCHIVEPSYKCHFVKVPKHGLIPELFIAFQVNPFAPGWKGKCNESVDCQDN 228
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 229 TNHNILQARNRIEEFFRSQAYIFNHNFnNTLPAMHFVDHSFQIVRIDSCHPGFGKNEGLHSNCATCCVVCGPGTFSPDVD 308
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQF-ETLPEIHYVEGSLQVVWIDRCRPGFGKNEILHPNCAECCVVCSPGTYSPDSG 159

                         170
                  ....*....|....*...
gi 1814777838 309 VTCQTCVSIQIYGAKSCP 326
Cdd:pfam07354 160 IHCLQCVSSLTYGAKSCP 177
 
Name Accession Description Interval E-value
Sp38 pfam07354
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 149-326 1.60e-107

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


Pssm-ID: 336682  Cd Length: 177  Bit Score: 311.04  E-value: 1.60e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 149 FTTKSCVGKYNDLLFRLLKKILDNLISDLSCHIVEPSYKCHFVKVPKHGLIPELFIAFQVNPFAPGWKGKCNESVDCQDN 228
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 229 TNHNILQARNRIEEFFRSQAYIFNHNFnNTLPAMHFVDHSFQIVRIDSCHPGFGKNEGLHSNCATCCVVCGPGTFSPDVD 308
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQF-ETLPEIHYVEGSLQVVWIDRCRPGFGKNEILHPNCAECCVVCSPGTYSPDSG 159

                         170
                  ....*....|....*...
gi 1814777838 309 VTCQTCVSIQIYGAKSCP 326
Cdd:pfam07354 160 IHCLQCVSSLTYGAKSCP 177
 
Name Accession Description Interval E-value
Sp38 pfam07354
Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding ...
 149-326 1.60e-107

Zona-pellucida-binding protein (Sp38); This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90-kDa family of zona pellucida glycoproteins in a calcium-dependent manner. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilization to occur.


Pssm-ID: 336682  Cd Length: 177  Bit Score: 311.04  E-value: 1.60e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 149 FTTKSCVGKYNDLLFRLLKKILDNLISDLSCHIVEPSYKCHFVKVPKHGLIPELFIAFQVNPFAPGWKGKCNESVDCQDN 228
Cdd:pfam07354   1 FTAAPCNSRYNDSFFRELKKILSKLISDLSCEVSLPSYECHSVKMPRRGLQSELFFTFQVNPFAPGWKDLCNRSLDCEDT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1814777838 229 TNHNILQARNRIEEFFRSQAYIFNHNFnNTLPAMHFVDHSFQIVRIDSCHPGFGKNEGLHSNCATCCVVCGPGTFSPDVD 308
Cdd:pfam07354  81 TNHRLLKAKDRIERFFRSQVYILKHQF-ETLPEIHYVEGSLQVVWIDRCRPGFGKNEILHPNCAECCVVCSPGTYSPDSG 159

                         170
                  ....*....|....*...
gi 1814777838 309 VTCQTCVSIQIYGAKSCP 326
Cdd:pfam07354 160 IHCLQCVSSLTYGAKSCP 177
NCD3G pfam07562
Nine Cysteines Domain of family 3 GPCR; This conserved sequence contains several ...
 275-314 8.03e-03

Nine Cysteines Domain of family 3 GPCR; This conserved sequence contains several highly-conserved Cys residues that are predicted to form disulphide bridges. It is predicted to lie outside the cell membrane, tethered to the pfam00003 in several receptor proteins.


Pssm-ID: 462210  Cd Length: 53  Bit Score: 34.15  E-value: 8.03e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1814777838 275 DSCHPGFGKN-EGLHSNCATCCVVCGPGTFSPDVDVTCQTC 314
Cdd:pfam07562   7 ESCPPGQRKSqQGGAPVCCWDCVPCPEGEISNTDSDTCKKC 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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