|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
36-348 |
0e+00 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 602.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 36 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDV 115
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPNYKEAVLELNASDDRGIDV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 116 VRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTD 195
Cdd:PLN03025 81 VRNKIKMFAQKKVTLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 196 AQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANI 275
Cdd:PLN03025 161 QEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLKGKF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812779111 276 DEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKT 348
Cdd:PLN03025 241 DDACDGLKQLYDLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKLCLVR 313
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
35-344 |
5.17e-128 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 369.59 E-value: 5.17e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 35 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGID 114
Cdd:PRK00440 4 EEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGEDWRENFLELNASDERGID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 115 VVRNKIKMFAQQKvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLT 194
Cdd:PRK00440 84 VIRNKIKEFARTA-PVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSPLK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 195 DAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNAN 274
Cdd:PRK00440 163 KEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELALNGD 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1812779111 275 IDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARL 344
Cdd:PRK00440 243 FTEAREKLRDLMIDyGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKL 313
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
67-344 |
1.25e-69 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 233.19 E-value: 1.25e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 67 GNVPNIIiagppgtGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKvtlPKG--RHKIIILDEAD 144
Cdd:PRK04132 571 GNLPTVL-------HNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTK---PIGgaSFKIIFLDEAD 640
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 145 SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFT 224
Cdd:PRK04132 641 ALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYI 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 225 AQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAH-LWHLGYSPEDIIGNIFRVC 303
Cdd:PRK04132 721 AEGDMRRAINILQAAAALDDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREiLLKQGLSGEDVLVQMHREV 800
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1812779111 304 KTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARL 344
Cdd:PRK04132 801 FNLPIDEPKKVELADKIGEYNFRLVEGANEMIQLEALLAQF 841
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
38-344 |
8.93e-64 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 205.99 E-value: 8.93e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASN--DRGIDV 115
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADffDQGKKY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 116 VRNKiKMFAQQKVTLPK-----------------------GRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172
Cdd:PRK12402 85 LVED-PRFAHFLGTDKRirsskidnfkhvlkeyasyrplsADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVF 252
Cdd:PRK12402 164 QPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITMEAAY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 253 KVC-DEPHPLLVKEMIQHCVNANIDEAYKILAHLwhL---GYSPEDIIGNIFRVCKTFQmAEYLKLEFIKEIGYTHMKIA 328
Cdd:PRK12402 244 EALgDVGTDEVIESLLDAAEAGDFTDARKTLDDL--LideGLSGGEVLEELLRVARSRY-RGDNLARLHRLAADADARLT 320
|
330
....*....|....*.
gi 1812779111 329 EGVNSLLQMAGLLARL 344
Cdd:PRK12402 321 DGANDRIQLEALLAEL 336
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
53-346 |
7.94e-48 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 163.22 E-value: 7.94e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 53 NEDTVSRLEVFAREGNVP-NIIIAGPPGTGKTTSILCLARALLGPALKDA------------------MLELNA---SND 110
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPhALLLHGPPGIGKTTLALALARDLLCENPEGGkacgqchsrlmaagnhpdLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 111 RGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRY 190
Cdd:COG0470 81 IGIDQIR-ELGEFLSLTPLE--GGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 191 TKLTDAQILTRLmnviEKERVpyTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFInsENVFKVCDEPHPLlvkEMIQHC 270
Cdd:COG0470 158 RPPSEEEALAWL----REEGV--DEDALEAILRLAGGDPRAAINLLQALAGRKELL--EDLAALLSRDRAL---ELLDAL 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812779111 271 VNANIDEAYKILAHLwhlgyspedIIGNIFrvcktFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQ 346
Cdd:COG0470 227 LKAEALELLDWLLKW---------LLDNLP-----LEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKLGR 288
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
35-248 |
2.02e-42 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 149.75 E-value: 2.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 35 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIII-AGPPGTGKTTSILCLARALlgpalkDA-MLELNASNDRg 112
Cdd:PHA02544 8 EFMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLhSPSPGTGKTTVAKALCNEV------GAeVLFVNGSDCR- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 113 IDVVRNKIKMFAQQkVTLpKGRHKIIILDEAD-SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYT 191
Cdd:PHA02544 81 IDFVRNRLTRFAST-VSL-TGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1812779111 192 KLTDA-------QILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQStFSGFGFINS 248
Cdd:PHA02544 159 VPTKEeqiemmkQMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQR-YASTGKIDA 221
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
36-251 |
2.32e-33 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 128.89 E-value: 2.32e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 36 LPWVEKYRPVKLNEIVGNEDTVSRLEVFARE---GNVPN-IIIAGPPGTGKTTSILCLARALLGPalkdaMLELNASNDR 111
Cdd:PRK04195 2 MPWVEKYRPKTLSDVVGNEKAKEQLREWIESwlkGKPKKaLLLYGPPGVGKTSLAHALANDYGWE-----VIELNASDQR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 112 GIDVVRNKIKMFAQQKvTLPKGRHKIIILDEADSM---TD-GAQQALRRTMeiysKTTRFALACNASD---KIIEPIQSR 184
Cdd:PRK04195 77 TADVIERVAGEAATSG-SLFGARRKLILLDEVDGIhgnEDrGGARAILELI----KKAKQPIILTANDpydPSLRELRNA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1812779111 185 CAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENV 251
Cdd:PRK04195 152 CLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDV 218
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
34-291 |
2.85e-33 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 128.79 E-value: 2.85e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 34 YElPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGP-------------- 96
Cdd:PRK14953 3 YI-PFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAyIFAGPRGTGKTTIARILAKVLncLNPqegepcgkcencve 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 97 ----ALKDaMLELNASNDRGIDVVRNKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACN 172
Cdd:PRK14953 82 idkgSFPD-LIEIDAASNRGIDDIRALRDAVSYTPI---KGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 173 ASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINS--- 248
Cdd:PRK14953 158 EYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLdQASTYGEGKVTIkvv 237
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1812779111 249 ENVFKVCDEPHpllVKEMIQHCVNANIDEAYKILAHLWHLGYS 291
Cdd:PRK14953 238 EEFLGIVSQES---VRKFLNLLLESDVDEAIKFLRTLEEKGYN 277
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
258-343 |
8.67e-31 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 112.18 E-value: 8.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 258 PHPLLVKEMIQHCVNANIDEAYKIL-AHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQ 336
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVrELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*..
gi 1812779111 337 MAGLLAR 343
Cdd:pfam08542 81 LSALLAA 87
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
44-296 |
4.77e-28 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 111.82 E-value: 4.77e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 44 PVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKD-----------AMLELN----- 106
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILAKALNCENGPTgepcgecescrAIAAGShpdvi 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 107 -----ASNdRGIDVVRNkIkmfaQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:COG2812 86 eidaeASN-IGVDDIRE-L----IEKVSYApvEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTfSGFGFINSENvfkvcdeph 259
Cdd:COG2812 160 TILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQA-IAFGLLDRRE--------- 229
|
250 260 270
....*....|....*....|....*....|....*..
gi 1812779111 260 plLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDII 296
Cdd:COG2812 230 --LLLDLLEALLAGDVAALLALAEELAKRGRDLKRFL 264
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
36-320 |
1.00e-24 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 105.28 E-value: 1.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 36 LPWVEKYRPVKLNEIVGNEDTVSRLEvfaregnvpNII----------IAGPPGTGKTTSILCLARAL--------LGPA 97
Cdd:PRK07133 6 KALYRKYRPKTFDDIVGQDHIVQTLK---------NIIksnkishaylFSGPRGTGKTSVAKIFANALncshktdlLEPC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 98 LK---------DaMLELNASNDRGIDVVR---NKIKMFAQQkvtlpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT 165
Cdd:PRK07133 77 QEcienvnnslD-IIEMDAASNNGVDEIReliENVKNLPTQ------SKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 166 RFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQ--STFSG- 242
Cdd:PRK07133 150 IFILATTEVHKIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEqvSIFGNn 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 243 ----------FGFINSENVFKvcdephplLVKEMiqhcVNANIDEAYKILAHLWHLGYSPE-------DIIGN--IFRVC 303
Cdd:PRK07133 230 kitlknveelFGLVSNENLIN--------LLNLL----YSKDIKEVLNILNQIKEQGIDPElllisliNLVKEfiIFNKT 297
|
330
....*....|....*..
gi 1812779111 304 KTFQMAEYLKLEFIKEI 320
Cdd:PRK07133 298 KDNSLLEYYSEEDLEKL 314
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
41-328 |
5.50e-24 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 102.54 E-value: 5.50e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGnEDTVSRLEVFAREGNVPN--IIIAGPPGTGKTTSILCLARALLGPALKDA----------------- 101
Cdd:PRK14962 7 KYRPKTFSEVVG-QDHVKKLIINALKKNSIShaYIFAGPRGTGKTTVARILAKSLNCENRKGVepcnecracrsidegtf 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK14962 86 mdVIELDAASNRGIDEIR-KIRDAVGYRPME--GKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQ--STFSGfGFINSENVFK---- 253
Cdd:PRK14962 163 TIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEqvWKFSE-GKITLETVHEalgl 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 254 VCDEphplLVKEMIQHCVNANIDEAYKILAHLWHLGYSP--------EDIIGNIFRVcKTFQMAEYLK--LEFIKEIGYT 323
Cdd:PRK14962 242 IPIE----VVRDYINAIFNGDVKRVFTVLDDVYYSGKDYevliqqaiEDLVEDLERE-RANDIIQVSRqlLNILREIKFA 316
|
....*
gi 1812779111 324 HMKIA 328
Cdd:PRK14962 317 EEKRL 321
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
40-236 |
4.70e-23 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 99.00 E-value: 4.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 40 EKYRPVKLNEIVGNEDTVSR---LEVFAREGNVPNIIIAGPPGTGKTTsilcLARALLGpALKDAMLELNASNDrGIDVV 116
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLGPgkpLRRMIEAGRLSSMILWGPPGTGKTT----LARIIAG-ATDAPFEALSAVTS-GVKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 117 RnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQAL-----RRTMEIYSKTTRfalacNASDKIIEPIQSRCAVLRYT 191
Cdd:PRK13342 78 R---EVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALlphveDGTITLIGATTE-----NPSFEVNPALLSRAQVFELK 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1812779111 192 KLTDA---QILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 236
Cdd:PRK13342 150 PLSEEdieQLLKRALEDKERGLVELDDEALDALARLANGDARRALNLL 197
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
41-242 |
4.15e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 95.71 E-value: 4.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA-------MLELNASNDRG 112
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKINQPGYDDPnedfsfnIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 113 IDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTK 192
Cdd:PRK14970 90 VDDIRNLID---QVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 193 LTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALN--NLQSTFSG 242
Cdd:PRK14970 167 ITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSifDRVVTFCG 218
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
51-185 |
5.72e-22 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 90.67 E-value: 5.72e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 51 VGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPalKDAMLELNASNDRGIDVVRNKIKMFA--QQKV 128
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRP--GAPFLYLNASDLLEGLVVAELFGHFLvrLLFE 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 129 TLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT------RFALACNASD--KIIEPIQSRC 185
Cdd:cd00009 79 LAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRidrenvRVIGATNRPLlgDLDRALYDRL 143
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
193-255 |
2.81e-21 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 86.04 E-value: 2.81e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812779111 193 LTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVC 255
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEVA 63
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
40-323 |
1.18e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 87.21 E-value: 1.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 40 EKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDA----------------- 101
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAKIFAKAINCLNPKDGdccnscsvcesintnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDVVRNKIKMFAQQKVTLPKgrhKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK05896 88 vdIVELDAASNNGVDEIRNIIDNINYLPTTFKY---KVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQ--STF--SGFGFINSENVFKVC 255
Cdd:PRK05896 165 TIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDqlSTFknSEIDIEDINKTFGLV 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1812779111 256 DEPHPLLVKEMIQhcvNANIDEAYKILAHLWHLGYSPEDIIGNIFRVckTFQMAEYLKLEFIKEIGYT 323
Cdd:PRK05896 245 DNNKKINLIELIQ---KNDIEELRNLINELESKGINFEAFCRDLINL--LIDLLVYQKTKNINLLKKL 307
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
41-303 |
3.33e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 85.61 E-value: 3.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSI----LCLaRALLGP------------ALKDA-- 101
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCAriisLCL-NCSNGPtsdpcgtchnciSIKNSnh 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII 178
Cdd:PRK14964 85 pdVIEIDAASNTSVD----DIKVILENSCYLPiSSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 179 EPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINSENVFKV--C 255
Cdd:PRK14964 161 VTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLeQAAIYSNNKISEKSVRDLlgC 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 256 DEPHPLLvkEMIQHCVNANIDEAYKILAHLWHLgYSP----EDIIGNIFRVC 303
Cdd:PRK14964 241 VDKHILE--DLVEAILLGDAQSALNVFRELCNT-SNPviilEGMLQIIYEIC 289
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
40-232 |
7.27e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 84.51 E-value: 7.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 40 EKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGPALKDA--------------- 101
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHAyLFSGPRGVGKTTTARLIAMAVncSGEDPKPCgecesclavrrgahp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 -MLELNASNDRGIDVVRNkikmfAQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKII 178
Cdd:PRK14963 86 dVLEIDAASNNSVEDVRD-----LREKVLLAplRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1812779111 179 EPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA 232
Cdd:PRK14963 161 PTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDA 214
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
41-251 |
1.21e-16 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 81.29 E-value: 1.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALLGPALKDA------------------ 101
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHAyLLTGTRGVGKTTIARILAKSLNCENAQHGepcgvcqsctqidagryv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 -MLELNASNDRGIDVVRNKIKMfAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
Cdd:PRK08691 89 dLLEIDAASNTGIDNIREVLEN-AQYAPTA--GKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINSENV 251
Cdd:PRK08691 166 VLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLdQAIALGSGKVAENDV 237
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
41-236 |
1.39e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 77.86 E-value: 1.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL---LGPALKDA--------------- 101
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALnceQGLTAEPCnvcppcveitegrsv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 -MLELNASNDRGIDVVR---NKIKMfaqqkvtLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDK 176
Cdd:PRK14965 89 dVFEIDGASNTGVDDIRelrENVKY-------LPsRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 177 IIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 236
Cdd:PRK14965 162 VPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTL 221
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
37-236 |
1.42e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 77.80 E-value: 1.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNV-PNIIIAGPPGTGKTTSILCLARAL-------------------LGP 96
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIARIFAKALncetaptgepcntceqcrkVTQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 97 ALKDAMLELNASNDRGIDVVRNKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDK 176
Cdd:PRK14959 85 GMHVDVVEIDGASNRGIDDAKRLKEAIGYAPM---EGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 177 IIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 236
Cdd:PRK14959 162 FPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
41-319 |
2.89e-15 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 76.61 E-value: 2.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALL---GP-------------ALKDA-- 101
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHAyLFSGLRGSGKTSSARIFARALVceqGPsstpcdtciqcqsALENRhi 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 -MLELNASNDRGIDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
Cdd:PRK08451 87 dIIEMDAASNRGIDDIRELIE---QTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPAT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINSENVFKVCDEPH 259
Cdd:PRK08451 164 ILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLdQAIIYCKNAITESKVADMLGLLD 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812779111 260 PLLVKEMIQHCVN---ANIDEAYKILAhlwhlGYSPEDIIGnifrvcktfQMAEYLKLEFIKE 319
Cdd:PRK08451 244 PSKLEDFFQAILNqdkEKLFELLKELE-----DYEAEMVLD---------EMMLFLKEKFLSK 292
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
43-236 |
4.56e-15 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 75.86 E-value: 4.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 43 RPVKLNEIVGNEDTVSR---LEVFAREGNVPNIIIAGPPGTGKTTsilcLARALLGpALKDAMLELNASNDrGIDVVRnk 119
Cdd:COG2256 20 RPRTLDEVVGQEHLLGPgkpLRRAIEAGRLSSMILWGPPGTGKTT----LARLIAN-ATDAEFVALSAVTS-GVKDIR-- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 120 iKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTME------IYSkTTRfalacNASDKIIEPIQSRCAVLRYTKL 193
Cdd:COG2256 92 -EVIEEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVEdgtitlIGA-TTE-----NPSFEVNSALLSRCRVFVLKPL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1812779111 194 TDAQILTRLMNVIEKE-------RVPYTDDGLEAIIFTAQGDMRQALNNL 236
Cdd:COG2256 165 SEEDLEQLLERALADDerglggyKLELDDEALEALARLADGDARRALNAL 214
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
41-232 |
1.74e-14 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 74.04 E-value: 1.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLE---VFAREGNVpnIIIAGPPGTGKTTSILCLARAL----------------------LG 95
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKnalRFNRAAHA--YLFSGIRGTGKTTLARIFAKALncqnptedqepcnqcasckeisSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 96 PALKdaMLELNASNDRGIDVVR--NKIKMFaqqkvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNA 173
Cdd:PRK06305 88 TSLD--VLEIDGASHRGIEDIRqiNETVLF-----TPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTE 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1812779111 174 SDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA 232
Cdd:PRK06305 161 IHKIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDA 219
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
41-244 |
3.31e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 73.69 E-value: 3.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL------------------LGPALKDA 101
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAyLFTGPRGVGKTSTARILAKAVncttndpkgrpcgtcemcRAIAEGSA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 M--LELNASNDRGIDVVRnKIKMFAQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK14950 89 VdvIEMDAASHTSVDDAR-EIIERVQFRPAL--ARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPA 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFG 244
Cdd:PRK14950 166 TILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYG 230
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
41-234 |
5.12e-14 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 72.67 E-value: 5.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL-------------------LGPALKD 100
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHAyIFFGPRGVGKTTIARILAKRLncenpignepcnectscleITKGISS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 101 AMLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
Cdd:PRK14956 91 DVLEIDAASNRGIENIR---ELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPET 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1812779111 181 IQSRCAVLRYTKLTdaqiLTRLMNVIEK----ERVPYTDDGLEAIIFTAQGDMRQALN 234
Cdd:PRK14956 168 ILSRCQDFIFKKVP----LSVLQDYSEKlckiENVQYDQEGLFWIAKKGDGSVRDMLS 221
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
36-299 |
2.78e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 70.66 E-value: 2.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 36 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL--LGPALKDA----------- 101
Cdd:PRK06645 9 IPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVncSALITENTtiktceqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 ----------MLELNASNDRGIDVVRNKIKMfAQQKVTlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALAC 171
Cdd:PRK06645 89 isfnnhnhpdIIEIDAASKTSVDDIRRIIES-AEYKPL--QGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 172 NASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA---LNNLQSTFSGFGFINS 248
Cdd:PRK06645 166 TEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAvsiLDQAASMSAKSDNIIS 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 249 ENVF-KVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNI 299
Cdd:PRK06645 246 PQVInQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESV 297
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
41-286 |
4.29e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 70.11 E-value: 4.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL-------LGPALKDA---------- 101
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSL-VHALETQKVHhaYLFTGTRGVGKTTLGRLLAKCLncktgvtAEPCNKCEncvainnnsf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK14957 88 idLIEIDAASRTGVEETK---EILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFS-------------GFGFI 246
Cdd:PRK14957 165 TILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISfcggelkqaqikqMLGII 244
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1812779111 247 NSENVFKVCD---EPHPLLVKEMIQH--CVNANIDEAYKILAHLW 286
Cdd:PRK14957 245 DSEEVYSIINaiiDNDPKAILPAIKNlaLTESSADAVLDRIAEIW 289
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
41-251 |
5.23e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 69.78 E-value: 5.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL-------LGPALKDA---------- 101
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRAL-TNALEQQRLHhaYLFTGTRGVGKTTLARILAKSLncetgvtATPCGVCSacleidsgrf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDVVRNKIKMfAQQKVTlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK14969 88 vdLIEVDAASNTQVDAMRELLDN-AQYAPT--RGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPV 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINSENV 251
Cdd:PRK14969 165 TVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLdQAIAYGGGTVNESEV 237
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
41-242 |
8.29e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 69.42 E-value: 8.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTT-------SILCLARALLGPALKDA----------- 101
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTcarifakTINCQNLTADGEACNECescvafneqrs 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDVVRNKIKmfaQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIE 179
Cdd:PRK14971 90 ynIHELDAASNNSVDDIRNLIE---QVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILP 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 180 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALN--NLQSTFSG 242
Cdd:PRK14971 167 TILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSifDQVVSFTG 231
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
41-296 |
1.93e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 68.26 E-value: 1.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL---LGPAL-------------KDAML 103
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAyIFSGPRGVGKTSSARAFARCLncvNGPTPmpcgecsscksidNDNSL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 104 ---ELNASNDRGIDVVRnKIK---MFAQQkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKI 177
Cdd:PRK06647 89 dviEIDGASNTSVQDVR-QIKeeiMFPPA-----SSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 178 IEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA---------LNNLQSTF----SGFG 244
Cdd:PRK06647 163 PATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAytlfdqvvsFSDSDITLeqirSKMG 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 245 FINSENVFKVcdephpllvkemIQHCVNANIDEAYKILAHLWHLGYSPEDII 296
Cdd:PRK06647 243 LTGDEFLEKL------------ASSILNEDAKELLCVLDSVFLSGVSVEQFL 282
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
35-82 |
4.35e-12 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 67.17 E-value: 4.35e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1812779111 35 ELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGK 82
Cdd:PRK04132 6 EKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
41-332 |
4.62e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 66.37 E-value: 4.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL---LG----PALKDA----------- 101
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLncqNGitsnPCRKCIickeiekglcl 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 -MLELNASNDRGIDVVRnkiKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
Cdd:PRK14961 89 dLIEIDAASRTKVEEMR---EILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFS-GFGFINSENVFK---VCD 256
Cdd:PRK14961 166 ILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINlGKGNINIKNVTDmlgLLN 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 257 EPHPLLVKEMIqhcVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKL----EFIKEIGYTHMKIAEGVN 332
Cdd:PRK14961 246 EKQSFLLTDAL---LKKDSKKTMLLLNKISSIGIEWENILIEMLRFLHHISMSQSFPKiwntIFIKNYKNQIQKIAQNNK 322
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
41-232 |
2.06e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 64.53 E-value: 2.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARAL-------------------------- 93
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVncqrmiddadylqevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 94 ---LGPALKDAmlELNASNDRGID---VVRNKIKMFAQqkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRF 167
Cdd:PRK14955 89 dfdAGTSLNIS--EFDAASNNSVDdirLLRENVRYGPQ------KGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 168 ALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA 232
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDA 225
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
41-232 |
2.64e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 64.58 E-value: 2.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALK-------------------- 99
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKAVNCQRMIddpvylqevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 100 --DAMLELN------ASNDRGIDV--VRNKIKMFAQqkvtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFAL 169
Cdd:PRK14954 89 dfDAGTSLNisefdaASNNSVDDIrqLRENVRYGPQ------KGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIF 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1812779111 170 ACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA 232
Cdd:PRK14954 163 ATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDA 225
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
72-190 |
3.53e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 59.91 E-value: 3.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 72 IIIAGPPGTGKTTsilcLARALLGpALKDAMLELNASN--DRGIDVVRNKI-KMFAQQKVTLPkgrhKIIILDEADSM-- 146
Cdd:pfam00004 1 LLLYGPPGTGKTT----LAKAVAK-ELGAPFIEISGSElvSKYVGESEKRLrELFEAAKKLAP----CVIFIDEIDALag 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1812779111 147 ---------TDGAQQALRRTMEIYSKTTR---FALACNASDKIIEPIQSRCAVLRY 190
Cdd:pfam00004 72 srgsggdseSRRVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIE 127
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
41-251 |
6.27e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 63.53 E-value: 6.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGnEDTVSRLEVFARE-GNVPNI-IIAGPPGTGKTTSILCLARAL-----LGPALKDAMLELNASND-RG 112
Cdd:PRK14960 8 KYRPRNFNELVG-QNHVSRALSSALErGRLHHAyLFTGTRGVGKTTIARILAKCLncetgVTSTPCEVCATCKAVNEgRF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 113 IDVV------RNKIKMFAQQKVTLP----KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQ 182
Cdd:PRK14960 87 IDLIeidaasRTKVEDTRELLDNVPyaptQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVI 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 183 SRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALN-NLQSTFSGFGFINSENV 251
Cdd:PRK14960 167 SRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSlTDQAIAYGQGAVHHQDV 236
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
41-233 |
9.91e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 62.97 E-value: 9.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL--LGPALKDAM--------------- 102
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHAyLFTGTRGVGKTTLSRILAKSLncTGADGEGGItaqpcgqcracteid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 103 -------LELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNAS 174
Cdd:PRK12323 89 agrfvdyIEMDAASNRGVD----EMAQLLDKAVYAPtAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1812779111 175 DKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQAL 233
Cdd:PRK12323 165 QKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDAL 223
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
41-305 |
1.37e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 62.58 E-value: 1.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEvfaregnvpNIII----------AGPPGTGKTTSILCLARALLGPALKDA--------- 101
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLK---------NAIKqgkishaylfSGPRGTGKTSAAKIFAKAVNCLNPPDGepcneceic 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 ----------MLELNASNDRGIDVVRNKIkmfaqQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTME------Iysk 163
Cdd:PRK05563 80 kaitngslmdVIEIDAASNNGVDEIRDIR-----DKVKYApsEAKYKVYIIDEVHMLSTGAFNALLKTLEeppahvI--- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 164 ttrFALACNASDKIIEPIQSRCAvlRY--TKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQAL-------- 233
Cdd:PRK05563 152 ---FILATTEPHKIPATILSRCQ--RFdfKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALsildqais 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 234 ---------NNLQSTfsgfGFINSENVFKvcdephpllvkeMIQHCVNANIDEAYKILAHLWHLGYSP----EDIIGnIF 300
Cdd:PRK05563 227 fgdgkvtyeDALEVT----GSVSQEALDD------------LVDAIVEGDVAKALKILEELLDEGKDPnrfiEDLIY-YL 289
|
....*...
gi 1812779111 301 R---VCKT 305
Cdd:PRK05563 290 RdllLVKT 297
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
44-233 |
1.69e-10 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 61.59 E-value: 1.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 44 PVKLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALL-------GP-ALKD-------------- 100
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILshpdpaeAPeTLADpdpaspvwrqiaqg 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 101 ---AMLELNASNDRG---------IDVVRNKIKMFAQqkvTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFA 168
Cdd:PRK09112 99 ahpNLLHITRPFDEKtgkfktaitVDEIRRVGHFLSQ---TSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFI 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 169 LACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKerVPYTDDGLEAIIFTAQGDMRQAL 233
Cdd:PRK09112 176 LISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSS--QGSDGEITEALLQRSKGSVRKAL 238
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
71-211 |
4.84e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 57.38 E-value: 4.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 71 NIIIAGPPGTGKTTSILCLARALLGPALKdaMLELNASNDRGIDVVRNKIKMFAQQKVTLPKG-------------RHKI 137
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGG--VIYIDGEDILEEVLDQLLLIIVGGKKASGSGElrlrlalalarklKPDV 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1812779111 138 IILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASdkIIepiqsrCAVLRYTKLTDAQILTRLMNVIEKERV 211
Cdd:smart00382 82 LILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLT--VI------LTTNDEKDLGPALLRRRFDRRIVLLLI 147
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
41-268 |
8.36e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 60.13 E-value: 8.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGID----- 114
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHAyLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDegrfp 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 115 -------VVRNKIKMFAQQKVTLP----KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQS 183
Cdd:PRK14958 89 dlfevdaASRTKVEDTRELLDNIPyaptKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 184 RCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL-QSTFSGFGFINSENVFKVCDEPHPLL 262
Cdd:PRK14958 169 RCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLdQSIAYGNGKVLIADVKTMLGTIEPLL 248
|
....*.
gi 1812779111 263 VKEMIQ 268
Cdd:PRK14958 249 LFDILE 254
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
41-233 |
1.87e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 58.96 E-value: 1.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLE------------VFAregnvpniiiaGPPGTGKTTSILCLARAL--LGP---------- 96
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTnaltqqrlhhayLFT-----------GTRGVGKTTVSRILAKSLncQGPdgqggitatp 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 97 -----ALKDA-------MLELNASNDRGIDvvrnKIKMFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSK 163
Cdd:PRK14951 78 cgvcqACRDIdsgrfvdYTELDAASNRGVD----EVQQLLEQAVYKPvQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPE 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 164 TTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQAL 233
Cdd:PRK14951 154 YLKFVLATTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDAL 223
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
46-200 |
8.67e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 56.19 E-value: 8.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 46 KLNEIVGNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKttSILC--LARALLGpalKDAMLE--------LNASNDRGID 114
Cdd:PRK05564 2 SFHTIIGHENIKNRIKNSIIKNRFSHaHIIVGEDGIGK--SLLAkeIALKILG---KSQQREyvdiiefkPINKKSIGVD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 115 VVRNKIKMFAQQKVtlpKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLT 194
Cdd:PRK05564 77 DIRNIIEEVNKKPY---EGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLS 153
|
....*.
gi 1812779111 195 DAQILT 200
Cdd:PRK05564 154 KEEIEK 159
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
52-194 |
8.81e-09 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 54.14 E-value: 8.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 52 GNEDTVSRLEVFAREGNVPN-IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGI------DVVR-----NK 119
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIesgnhpDLVIiepegQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 120 IKM----FAQQKVTLP--KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKL 193
Cdd:pfam13177 81 IKIdqirELQKEFSKSpyEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160
|
.
gi 1812779111 194 T 194
Cdd:pfam13177 161 S 161
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
35-237 |
1.25e-08 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 56.60 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 35 ELPWVEKYRPVKLNEIVGN-----EDTVSRLEVFAreGNVPNIIIAGPPGTGKTTsilcLARaLLGPALKDAMLELNASN 109
Cdd:PRK13341 15 EAPLADRLRPRTLEEFVGQdhilgEGRLLRRAIKA--DRVGSLILYGPPGVGKTT----LAR-IIANHTRAHFSSLNAVL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 110 dRGIDVVRNKIKMfAQQKVtlpkGRH---KIIILDEADSMTDGAQQAL-----RRTMEIYSKTTRfalacNASDKIIEPI 181
Cdd:PRK13341 88 -AGVKDLRAEVDR-AKERL----ERHgkrTILFIDEVHRFNKAQQDALlpwveNGTITLIGATTE-----NPYFEVNKAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 182 QSRCAVLRYTKLTDA---QILTRLMNviEKER------VPYTDDGLEAIIFTAQGDMRQALNNLQ 237
Cdd:PRK13341 157 VSRSRLFRLKSLSDEdlhQLLKRALQ--DKERgygdrkVDLEPEAEKHLVDVANGDARSLLNALE 219
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
41-242 |
1.63e-08 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 56.04 E-value: 1.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLEVFAREGNVPNI-IIAGPPGTGKTTSILCLARAL-------------------LGPALKD 100
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHAyLFSGPRGCGKTSSARILARSLncaqgptatpcgvcescvaLAPNGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 101 AM--LELNASNDRGIDVVRNkikmFAQQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKI 177
Cdd:PRK14952 86 SIdvVELDAASHGGVDDTRE----LRDRAFYAPaQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 178 IEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSG 242
Cdd:PRK14952 162 LPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAG 226
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
41-233 |
3.50e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 55.24 E-value: 3.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 41 KYRPVKLNEIVGNEDTVSRLeVFAREGNVPN--IIIAGPPGTGKTTSILCLARAL------------LGPALKDA----- 101
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRAL-THALDGGRLHhaYLFTGTRGVGKTTLSRIFAKALncetgvtsqpcgVCRACREIdegrf 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 102 --MLELNASNDRGIDvvrnkiKMFA--QQKVTLP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDK 176
Cdd:PRK07003 88 vdYVEMDAASNRGVD------EMAAllERAVYAPvDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1812779111 177 IIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQAL 233
Cdd:PRK07003 162 IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDAL 218
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
37-237 |
1.05e-07 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 53.42 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-----IIIAGPPGTGKTTSILCLARaLLGPALK---DAMLELNAS 108
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSK-ELGIQVQewsNPTLPDFQK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 109 ND-RGIDVVRNKIKMFAQQKVTLP-----------------KGRHKIIILDEADSMTDGAQQALRRTME-IYSKTTRFAL 169
Cdd:TIGR00602 152 NDhKVTLSLESCFSNFQSQIEVFSefllratnklqmlgddlMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGRCPL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 170 AC-----------------NASDKIIEPIQSRCAVLR---------YTKLTDAQILTRLMNVI-EKERVPYTDDgLEAII 222
Cdd:TIGR00602 232 VFiiteslegdnnqrrllfPAETIMNKEILEEPRVSNisfnpiaptIMKKFLNRIVTIEAKKNgEKIKVPKKTS-VELLC 310
|
250
....*....|....*
gi 1812779111 223 FTAQGDMRQALNNLQ 237
Cdd:TIGR00602 311 QGCSGDIRSAINSLQ 325
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
110-187 |
4.26e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 50.89 E-value: 4.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 110 DRGIDVVRN---KIKMFAQQkvtlpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCA 186
Cdd:PRK06871 86 DIGVDQVREineKVSQHAQQ------GGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
|
.
gi 1812779111 187 V 187
Cdd:PRK06871 160 T 160
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
196-238 |
2.44e-06 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 44.38 E-value: 2.44e-06
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1812779111 196 AQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQS 238
Cdd:cd18133 4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQR 46
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
72-170 |
4.98e-06 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 45.41 E-value: 4.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 72 IIIAGPPGTGKTTSILCLARALlgPALKDAMLELNASNDRGIDVVRNKI-------KMFAQQKVTLPK---------GRH 135
Cdd:pfam13401 8 LVLTGESGTGKTTLLRRLLEQL--PEVRDSVVFVDLPSGTSPKDLLRALlralglpLSGRLSKEELLAalqqlllalAVA 85
|
90 100 110
....*....|....*....|....*....|....*
gi 1812779111 136 KIIILDEADSMTDGAQQALRRTMEIYSKTTRFALA 170
Cdd:pfam13401 86 VVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
47-159 |
8.01e-06 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 46.42 E-value: 8.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 47 LNEIVGNEDTVSRLEVFARE----------GNVP--NIIIAGPPGTGKTTsilcLARALLGpALKDAMLELNASndrGI- 113
Cdd:COG1223 1 LDDVVGQEEAKKKLKLIIKElrrrenlrkfGLWPprKILFYGPPGTGKTM----LAEALAG-ELKLPLLTVRLD---SLi 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 114 -----DVVRNKIKMFAQQKvtlpkgRHK-IIILDEADSMtdgaqqALRRTME 159
Cdd:COG1223 73 gsylgETARNLRKLFDFAR------RAPcVIFFDEFDAI------AKDRGDQ 112
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
34-232 |
3.61e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 45.72 E-value: 3.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 34 YElPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNV-PNIIIAGPPGTGKTTSILCLARAL------------------- 93
Cdd:PRK14948 3 YE-PLHHKYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSARILAKSLnclnsdkptpepcgkcelc 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 94 ----LGPALkDaMLELNASNDRGIDVVRNKIK--MFAqqkvtlP-KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTR 166
Cdd:PRK14948 82 raiaAGNAL-D-VIEIDAASNTGVDNIRELIEraQFA------PvQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812779111 167 FALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQA 232
Cdd:PRK14948 154 FVLATTDPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDA 219
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
70-96 |
3.68e-05 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 45.53 E-value: 3.68e-05
10 20
....*....|....*....|....*..
gi 1812779111 70 PNIIIAGPPGTGKTTSILCLARALLGP 96
Cdd:COG1401 222 KNVILAGPPGTGKTYLARRLAEALGGE 248
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
37-100 |
5.20e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 43.41 E-value: 5.20e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1812779111 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN-----IIIAGPPGTGKTTSILCLARaLLGPALKD 100
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSK-ELGPKYRE 75
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
43-84 |
8.16e-05 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 43.97 E-value: 8.16e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1812779111 43 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTT 84
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFieaAKKRGEAldHVLLYGPPGLGKTT 66
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
39-93 |
8.51e-05 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 44.13 E-value: 8.51e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1812779111 39 VEKYRPVKLNEIVGNEDTVSRL-----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARAL 93
Cdd:COG0464 148 LLELREAILDDLGGLEEVKEELrelvalplkrpELREEYGLPPprGLLLYGPPGTGKTLLARALAGEL 215
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
43-98 |
9.77e-05 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 42.10 E-value: 9.77e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1812779111 43 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTTSILCLARAL-------LGPAL 98
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFieaAKQRGEAldHVLLYGPPGLGKTTLANIIANEMgvniritSGPAI 69
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
47-178 |
2.22e-04 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 41.08 E-value: 2.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 47 LNEIVGNEDTVSRLEVFAREGNVpnIIIAGPPGTGKTTSILCLARaLLGPALKDAMLELNASNDRGIDVVRNKIKMFAQ- 125
Cdd:cd00267 5 LSFRYGGRTALDNVSLTLKAGEI--VALVGPNGSGKSTLLRAIAG-LLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQl 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 126 -----QKVTLPK---GRHKIIILDEADSMTDGA-QQALRRTMEIYSKTTR--------FALACNASDKII 178
Cdd:cd00267 82 sggqrQRVALARallLNPDLLLLDEPTSGLDPAsRERLLELLRELAEEGRtviivthdPELAELAADRVI 151
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
65-159 |
3.16e-04 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 42.20 E-value: 3.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 65 REGNVpnIIIAGPPGTGKTTSILCLARA------LLG-PALKDAMLELNASNDRGiDVVRNKIKMFAQQKVTLPKGRHKI 137
Cdd:COG3598 11 PEGGV--TLLAGPPGTGKSFLALQLAAAvaaggpWLGrRVPPGKVLYLAAEDDRG-ELRRRLKALGADLGLPFADLDGRL 87
|
90 100
....*....|....*....|...
gi 1812779111 138 IILDEADSMTD-GAQQALRRTME 159
Cdd:COG3598 88 RLLSLAGDLDDtDDLEALERAIE 110
|
|
| Mg_chelatase |
pfam01078 |
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ... |
47-109 |
3.19e-04 |
|
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.
Pssm-ID: 426032 [Multi-domain] Cd Length: 207 Bit Score: 41.37 E-value: 3.19e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1812779111 47 LNEIVGNEDTVSRLEVFAREGNvpNIIIAGPPGTGKTTsilcLARALLG--PALKDA-MLELNASN 109
Cdd:pfam01078 2 LADVKGQEQAKRALEIAAAGGH--NLLMIGPPGSGKTM----LAKRLPGilPPLTEAeALEVTAIH 61
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
46-146 |
3.80e-04 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 40.34 E-value: 3.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 46 KLNEIVGNEDTVSRLEVFaREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKdamLELNASNDRGIDVVRNKI-KMFA 124
Cdd:cd19481 4 SLREAVEAPRRGSRLRRY-GLGLPKGILLYGPPGTGKTLLAKALAGELGLPLIV---VKLSSLLSKYVGESEKNLrKIFE 79
|
90 100
....*....|....*....|..
gi 1812779111 125 QqkvtLPKGRHKIIILDEADSM 146
Cdd:cd19481 80 R----ARRLAPCILFIDEIDAI 97
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
43-84 |
4.18e-04 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 41.60 E-value: 4.18e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1812779111 43 RPVKLNEIVGNEDTVSRLEVF---AREGNVP--NIIIAGPPGTGKTT 84
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFieaAKKRGEAldHVLLYGPPGLGKTT 69
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
73-143 |
5.14e-04 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 39.53 E-value: 5.14e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1812779111 73 IIAGPPGTGKTTSILCLARALLGPALKDAMLeLNASNDRGIDVVRnkikmfaqqkvtlpkgrhkIIILDEA 143
Cdd:cd17934 3 LIQGPPGTGKTTTIAAIVLQLLKGLRGKRVL-VTAQSNVAVDNVD-------------------VVIIDEA 53
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
49-95 |
6.26e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 40.18 E-value: 6.26e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1812779111 49 EIVGNEDTVSRLEVF---AREGNVPNIIIAGPPGTGKTTSILCLARALLG 95
Cdd:pfam13191 1 RLVGREEELEQLLDAldrVRSGRPPSVLLTGEAGTGKTTLLRELLRALER 50
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
193-237 |
8.15e-04 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 37.61 E-value: 8.15e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1812779111 193 LTDAQILTRLMNVIEKER------VPYTDDGLEAIIFTAQGDMRQALNNLQ 237
Cdd:cd18139 1 LSEEDLEKLLKRALEDKErggdrkVTIDDEALELLAEAADGDARSALNLLE 51
|
|
| ExeA |
COG3267 |
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ... |
72-156 |
8.45e-04 |
|
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442498 [Multi-domain] Cd Length: 261 Bit Score: 40.54 E-value: 8.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 72 IIIAGPPGTGKTTSILCLARAL-------------LGPA--LKDAMLELNASNDRgidvvRNKIKMFAQQKVTL----PK 132
Cdd:COG3267 46 VVLTGEVGTGKTTLLRRLLERLpddvkvayipnpqLSPAelLRAIADELGLEPKG-----ASKADLLRQLQEFLlelaAA 120
|
90 100
....*....|....*....|....
gi 1812779111 133 GRHKIIILDEADSMTDGAQQALRR 156
Cdd:COG3267 121 GRRVVLIIDEAQNLPPETLEELRL 144
|
|
| Viral_helicase1 |
pfam01443 |
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated ... |
72-143 |
8.54e-04 |
|
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated and NTPase activity. This helicase has multiple roles at different stages of viral RNA replication, as dissected by mutational analysis.
Pssm-ID: 366646 [Multi-domain] Cd Length: 227 Bit Score: 40.44 E-value: 8.54e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1812779111 72 IIIAGPPGTGKTTSILCLARALLG--PALKDAmlelnasNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEA 143
Cdd:pfam01443 1 IVVHGVPGCGKSTLIRKLLRTSRVirPTAELR-------TEGKPDLPNLNVRTVDTFLMALLKPTGKILILDEY 67
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
74-185 |
1.01e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 40.67 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 74 IAGPPGTGKTTSILCLARALLGP---------------ALKDA----------MLELnasndrGIDVVRNKIKMFAQQKV 128
Cdd:PRK07940 41 FTGPPGSGRSVAARAFAAALQCTdpdepgcgecracrtVLAGThpdvrvvapeGLSI------GVDEVRELVTIAARRPS 114
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1812779111 129 TlpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRC 185
Cdd:PRK07940 115 T---GRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRC 168
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
124-185 |
1.38e-03 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 40.17 E-value: 1.38e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1812779111 124 AQQKVTLpkGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRC 185
Cdd:PRK06090 100 AQESSQL--NGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRC 159
|
|
| AAA_11 |
pfam13086 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
73-102 |
2.42e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 404072 [Multi-domain] Cd Length: 248 Bit Score: 38.86 E-value: 2.42e-03
10 20 30
....*....|....*....|....*....|
gi 1812779111 73 IIAGPPGTGKTTSILCLARALLGPALKDAM 102
Cdd:pfam13086 17 LIQGPPGTGKTTTIVELIRQLLSYPATSAA 46
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
42-93 |
2.44e-03 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 39.45 E-value: 2.44e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1812779111 42 YRPvklNEIVGNEDTVSR----LEVFAREGNVPNIIIAGPPGTGKTTSILCLARAL 93
Cdd:COG1474 23 YVP---DRLPHREEEIEElasaLRPALRGERPSNVLIYGPTGTGKTAVAKYVLEEL 75
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
70-148 |
2.73e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 37.92 E-value: 2.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 70 PNIIIAGPPGTGKTTSILCLARA---------LLGPALKDAmleLNASNDRGIDVV-------RNKIKMFAQQKVTlPKG 133
Cdd:cd17933 13 RVSVLTGGAGTGKTTTLKALLAAleaegkrvvLAAPTGKAA---KRLSESTGIEAStihrllgINPGGGGFYYNEE-NPL 88
|
90
....*....|....*
gi 1812779111 134 RHKIIILDEAdSMTD 148
Cdd:cd17933 89 DADLLIVDEA-SMVD 102
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
58-146 |
3.27e-03 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 37.18 E-value: 3.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 58 SRLEVFAREGNVPNIIIAGPPGTGKTTSI-------LCLARALLGPALKDAMLelnasndrgiDVVRNKIKMFAQQKV-- 128
Cdd:cd18043 3 SQEAAIISARNGKNVVIQGPPGTGKSQTIaniianaLARGKRVLFVSEKKAAL----------DVVRFPCWIMSPLSVsq 72
|
90 100
....*....|....*....|
gi 1812779111 129 TLPKGRHK--IIILDEADSM 146
Cdd:cd18043 73 YLPLNRNLfdLVIFDEASQI 92
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
132-233 |
3.69e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 39.32 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1812779111 132 KGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERV 211
Cdd:PRK14949 117 RGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQL 196
|
90 100
....*....|....*....|..
gi 1812779111 212 PYTDDGLEAIIFTAQGDMRQAL 233
Cdd:PRK14949 197 PFEAEALTLLAKAANGSMRDAL 218
|
|
| DEXXQc_SETX |
cd18042 |
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in ... |
68-121 |
4.96e-03 |
|
DEXXQ-box helicase domain of SETX; The RNA/DNA helicase senataxin (SETX) plays a role in transcription, neurogenesis, and antiviral response. SEXT is an R-loop-associated protein that is thought to function as an RNA/DNA helicase. R-loops consist of RNA/DNA hybrids, formed during transcription when nascent RNA hybridizes to the DNA template strand, displacing the non-template DNA strand. Mutations in SETX are linked to two neurodegenerative disorders: ataxia with oculomotor apraxia type 2 (AOA2) and amyotrophic lateral sclerosis type 4 (ALS4). S. cerevisiae homolog splicing endonuclease 1 (Sen1) is an exclusively nuclear protein, important for nucleolar organization. S. cerevisiae Sen1 and its ortholog, the Schizosaccharomyces pombe Sen1, share conserved domains and belong to the family I class of helicases. Both proteins translocate 5' to 3' and unwind both DNA and RNA duplexes and also RNA/DNA hybrids in vitro. SETX is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438712 [Multi-domain] Cd Length: 218 Bit Score: 37.96 E-value: 4.96e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1812779111 68 NVPNI-IIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIK 121
Cdd:cd18042 15 NSPGItLIQGPPGTGKTKTIVGILSVLLAGKYRKYYEKVKKKLRKLQRNLNNKKK 69
|
|
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
71-95 |
6.96e-03 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 37.13 E-value: 6.96e-03
10 20
....*....|....*....|....*
gi 1812779111 71 NIIIAGPPGTGKTTsilcLARALLG 95
Cdd:cd01130 14 NILISGGTGSGKTT----LLNALLS 34
|
|
| DEXXQc_DNA2 |
cd18041 |
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses ... |
73-94 |
7.20e-03 |
|
DEXXQ-box helicase domain of DNA2; DNA2 (DNA Replication Helicase/Nuclease 2) possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5-3 helicase, and endonuclease activities, and is involved in DNA replication and DNA repair in the nucleus and mitochondrion. It is involved in Okazaki fragment processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. It is also involved in 5-end resection of DNA during double-strand break (DSB) repair; it is recruited by BLM and mediates the cleavage of 5-ssDNA, while the 3-ssDNA cleavage is prevented by the presence of RPA. DNA2 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350799 [Multi-domain] Cd Length: 203 Bit Score: 37.22 E-value: 7.20e-03
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
193-234 |
9.37e-03 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 34.40 E-value: 9.37e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1812779111 193 LTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALN 234
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALS 42
|
|
| |
