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Conserved domains on  [gi|1807916153|ref|XP_032247247|]
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acyl-protein thioesterase 2 isoform X2 [Phoca vitulina]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10491393)

alpha/beta hydrolase similar to acyl-protein thioesterase that hydrolyzes fatty acids from S-acylated cysteine residues in proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 119-336 7.01e-114

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


:

Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 328.95  E-value: 7.01e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 119 LTDAATVSGAERETAAVIFLHGLGDTGHSWADALST-IRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDE 197
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTeAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 198 AGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAIL 277
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTKKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1807916153 278 QCHGELDPMVPVRFGALTAEKLRSVVTpaRVQFKTYPGVMHSSCPQEMAAVKEFLEKLL 336
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 119-336 7.01e-114

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 328.95  E-value: 7.01e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 119 LTDAATVSGAERETAAVIFLHGLGDTGHSWADALST-IRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDE 197
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTeAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 198 AGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAIL 277
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTKKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1807916153 278 QCHGELDPMVPVRFGALTAEKLRSVVTpaRVQFKTYPGVMHSSCPQEMAAVKEFLEKLL 336
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
128-337 6.39e-51

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 167.78  E-value: 6.39e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 128 AERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVtlnmkMVMPSWFDLMGLSPDapEDEAGIKKAAENI 207
Cdd:COG0400     1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEGR--EDEEGLAAAAEAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 208 KALIEHEMKN-GIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLhRAFPQAANGSAKDLAILQCHGELDPM 286
Cdd:COG0400    74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPG-EEALPAPEAALAGTPVFLAHGTQDPV 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1807916153 287 VPVRFGALTAEKLRSvvTPARVQFKTYPGvMHSSCPQEMAAVKEFLEKLLP 337
Cdd:COG0400   153 IPVERAREAAEALEA--AGADVTYREYPG-GHEISPEELADARAWLAERLA 200
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 127-254 3.74e-03

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 39.45  E-value: 3.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153  127 GAERETAAVIFLHGLGDTGHSWadalstirLPHVKYICPHAPRIPVtlnmkmvmpswfDLMG---------LSPDAPEDE 197
Cdd:PLN02980  1366 GQNAEGSVVLFLHGFLGTGEDW--------IPIMKAISGSARCISI------------DLPGhggskiqnhAKETQTEPT 1425

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1807916153  198 AGIKKAAENIKALIEHemkngIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS 254
Cdd:PLN02980  1426 LSVELVADLLYKLIEH-----ITPGKVTLVGYSMGARIALYMALRFSDKIEGAVIIS 1477
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 119-336 7.01e-114

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 328.95  E-value: 7.01e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 119 LTDAATVSGAERETAAVIFLHGLGDTGHSWADALST-IRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDE 197
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTeAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 198 AGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAIL 277
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTKKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1807916153 278 QCHGELDPMVPVRFGALTAEKLRSVVTpaRVQFKTYPGVMHSSCPQEMAAVKEFLEKLL 336
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
128-337 6.39e-51

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 167.78  E-value: 6.39e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 128 AERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVtlnmkMVMPSWFDLMGLSPDapEDEAGIKKAAENI 207
Cdd:COG0400     1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEGR--EDEEGLAAAAEAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 208 KALIEHEMKN-GIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLhRAFPQAANGSAKDLAILQCHGELDPM 286
Cdd:COG0400    74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPG-EEALPAPEAALAGTPVFLAHGTQDPV 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1807916153 287 VPVRFGALTAEKLRSvvTPARVQFKTYPGvMHSSCPQEMAAVKEFLEKLLP 337
Cdd:COG0400   153 IPVERAREAAEALEA--AGADVTYREYPG-GHEISPEELADARAWLAERLA 200
COG4099 COG4099
Predicted peptidase [General function prediction only];
135-320 1.65e-15

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 74.62  E-value: 1.65e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 135 VIFLHGLGDTGHswaDALSTIRLPHVKYICP-HAPRIPVtlnmkMVmpswfdlmgLSPDAPEDEA-GIKKAAENIKALIE 212
Cdd:COG4099    52 VLFLHGAGERGT---DNEKQLTHGAPKFINPeNQAKFPA-----IV---------LAPQCPEDDYwSDTKALDAVLALLD 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 213 HEMKN-GIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWlplhrAFPQAANgSAKDLAILQCHGELDPMVPVRF 291
Cdd:COG4099   115 DLIAEyRIDPDRIYLTGLSMGGYGTWDLAARYPDLFAAAVPICGG-----GDPANAA-NLKKVPVWIFHGAKDDVVPVEE 188

                         170       180
                  ....*....|....*....|....*....
gi 1807916153 292 GALTAEKLRSVvtPARVQFKTYPGVMHSS 320
Cdd:COG4099   189 SRAMVEALKAA--GADVKYTEYPGVGHNS 215
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
128-334 4.11e-12

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 64.64  E-value: 4.11e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 128 AERETAAVIFLHGLGDTGHSW---ADALstirlphvkyicpHAPRIPVTLnmkmvmpswFDL--MGLSPDAPEDEAGIKK 202
Cdd:COG2267    24 AGSPRGTVVLVHGLGEHSGRYaelAEAL-------------AAAGYAVLA---------FDLrgHGRSDGPRGHVDSFDD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 203 AAENIKALIEHEMKNgiPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS---CWLPLH-------RAFPQAANGSAK 272
Cdd:COG2267    82 YVDDLRAALDALRAR--PGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLApayRADPLLgpsarwlRALRLAEALARI 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1807916153 273 DLAILQCHGELDPMVPVRFGALTAEKLrsvvtPARVQFKTYPG----VMHSSCPQE-MAAVKEFLEK 334
Cdd:COG2267   160 DVPVLVLHGGADRVVPPEAARRLAARL-----SPDVELVLLPGarheLLNEPAREEvLAAILAWLER 221
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 134-335 1.26e-10

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 60.40  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 134 AVIFLHGLGDTGHSW---ADALStirlPHVKYICPhapripvtlnmkmvmpswfDL--MGLSpDAPEDEAGIKKAAENIK 208
Cdd:COG0596    25 PVVLLHGLPGSSYEWrplIPALA----AGYRVIAP-------------------DLrgHGRS-DKPAGGYTLDDLADDLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 209 ALIEHEmknGIPanRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWL---------------PLHRAFPQAANGSAKD 273
Cdd:COG0596    81 ALLDAL---GLE--RVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLaalaeplrrpglapeALAALLRALARTDLRE 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1807916153 274 LA------ILQCHGELDPMVPVRFGALTAEKLRsvvtpaRVQFKTYPGV---MHSSCPQEMA-AVKEFLEKL 335
Cdd:COG0596   156 RLaritvpTLVIWGEKDPIVPPALARRLAELLP------NAELVVLPGAghfPPLEQPEAFAaALRDFLARL 221
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
191-336 1.59e-08

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 54.11  E-value: 1.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 191 PDAPED-EAGIKKAAENIKALiehemknGIPANRIVLGGFSQGGALSLYTALTCPHP----LAGIVALSCWLPLhRAFPq 265
Cdd:COG0657    61 PAALEDaYAALRWLRANAAEL-------GIDPDRIAVAGDSAGGHLAAALALRARDRggprPAAQVLIYPVLDL-TASP- 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 266 aANGSAKDLA-ILQCHGELDPMvpVRFGALTAEKLRSVVTParVQFKTYPGVMHSSC--------PQEMAAVKEFLEKLL 336
Cdd:COG0657   132 -LRADLAGLPpTLIVTGEADPL--VDESEALAAALRAAGVP--VELHVYPGGGHGFGllaglpeaRAALAEIAAFLRRAL 206
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
179-319 4.43e-08

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 53.05  E-value: 4.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 179 VMPSWFDlmGLSPDAPEDEAG-------IKKAAENIKALIEHEMKN-GIPANRIVLGGFSQGGALSLYTALTCPhPLAGI 250
Cdd:COG0412    60 LAPDLYG--RGGPGDDPDEARalmgaldPELLAADLRAALDWLKAQpEVDAGRVGVVGFCFGGGLALLAAARGP-DLAAA 136

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1807916153 251 VALSCWLPLHRAFPQAANGSAKdlaILQCHGELDPMVPVRFGALTAEKLRSvvTPARVQFKTYPGVMHS 319
Cdd:COG0412   137 VSFYGGLPADDLLDLAARIKAP---VLLLYGEKDPLVPPEQVAALEAALAA--AGVDVELHVYPGAGHG 200
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
207-337 3.24e-07

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 50.40  E-value: 3.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 207 IKALIEHemkNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSC------WLPLHRAFPQAANGSAKDLAI---- 276
Cdd:COG1506    81 IDYLAAR---PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGvsdlrsYYGTTREYTERLMGGPWEDPEayaa 157

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1807916153 277 ---------LQC-----HGELDPMVPVRFGALTAEKLRSvvTPARVQFKTYPGVMH----SSCPQEMAAVKEFLEKLLP 337
Cdd:COG1506   158 rsplayadkLKTpllliHGEADDRVPPEQAERLYEALKK--AGKPVELLVYPGEGHgfsgAGAPDYLERILDFLDRHLK 234
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 134-254 2.54e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 47.88  E-value: 2.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 134 AVIFLHGLGDTGHSWADALSTIRLPHVKYICphapripvtlnmkmvmpswFDLMGL--SPDAPEDEAGIKKA-AENIKAL 210
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIA-------------------LDLRGFgkSSRPKAQDDYRTDDlAEDLEYI 62

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1807916153 211 IEHemkNGIPanRIVLGGFSQGGALSLYTALTCPHPLAGIVALS 254
Cdd:pfam00561  63 LEA---LGLE--KVNLVGHSMGGLIALAYAAKYPDRVKALVLLG 101
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
135-315 2.73e-06

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 48.31  E-value: 2.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 135 VIFLHGLGDTGHSWADALstiRLPHV--KYIcpHAPRIPVTLnmkMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIE 212
Cdd:COG2382   115 LYLLDGGGGDEQDWFDQG---RLPTIldNLI--AAGKIPPMI---VVMPDGGDGGDRGTEGPGNDAFERFLAEELIPFVE 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 213 HEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS---CWLPLHRAFPQ-----AANGSAKDLAILQCHGELD 284
Cdd:COG2382   187 KNYRVSADPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFSgsfWWPPGDADRGGwaellAAGAPKKPLRFYLDVGTED 266

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1807916153 285 PMVPvrfgalTAEKLRSVVTPA--RVQFKTYPG 315
Cdd:COG2382   267 DLLE------ANRALAAALKAKgyDVEYREFPG 293
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 133-302 7.78e-06

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 46.92  E-value: 7.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 133 AAVIFLHGLGDTG---------HSWADALSTIrlphVKYicPHAPRipvtlnmKMVMPSWFDLMGLSPDAPEDEAGIkka 203
Cdd:COG3509    54 PLVVALHGCGGSAadfaagtglNALADREGFI----VVY--PEGTG-------RAPGRCWNWFDGRDQRRGRDDVAF--- 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 204 aenIKALIEHEMKN-GIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCwLPLHRAFPQAANgSAKDLAILQCHGE 282
Cdd:COG3509   118 ---IAALVDDLAARyGIDPKRVYVTGLSAGGAMAYRLACEYPDVFAAVAPVAG-LPYGAASDAACA-PGRPVPVLVIHGT 192

                         170       180
                  ....*....|....*....|
gi 1807916153 283 LDPMVPVRFGALTAEKLRSV 302
Cdd:COG3509   193 ADPTVPYAGAEETLAQWAAL 212
FSH1 pfam03959
Serine hydrolase (FSH1); This is a family of serine hydrolases.
 135-288 4.22e-04

Serine hydrolase (FSH1); This is a family of serine hydrolases.


Pssm-ID: 461110  Cd Length: 208  Bit Score: 41.11  E-value: 4.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 135 VIFLHGLGDTGHSWADALSTIRlPHVK------------YICPHAPRIPVTLNMKMVMP------SWFdlmgLSPDAPED 196
Cdd:pfam03959   6 VLCLHGFGQSGEIFRAKTGALR-KLLKklgvefvyldapFELAEPADLPGSESEKDEGEddepyrAWF----FGDDDTNE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 197 EAGIKKAaenIKALIEHEMKNGiPANRIVlgGFSQGGALSLYTA------LTCPHP-LAGIVALSCWLPLHRAFPQAANG 269
Cdd:pfam03959  81 YLGLDES---LDYVRDYIKENG-PFDGIL--GFSQGAALAAILAslleegLPLSHPpLKFAILFSGFRPRPPIYQEYYSE 154

                         170
                  ....*....|....*....
gi 1807916153 270 SAKDLAILQCHGELDPMVP 288
Cdd:pfam03959 155 DPIQTPSLHVIGELDTVVP 173
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
134-335 4.25e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 41.08  E-value: 4.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 134 AVIFLHGLGDTGHS---WADAL-------STIRLP-HvkyicphapripvtlnmkmvmpswfdlmGLSPDAPEdEAGIKK 202
Cdd:COG1647    17 GVLLLHGFTGSPAEmrpLAEALakagytvYAPRLPgH----------------------------GTSPEDLL-KTTWED 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 203 AAENIKALIEhEMKNGipANRIVLGGFSQGGALSLYTALTCPHpLAGIVALS-------------CWLPLHRAFPQAANG 269
Cdd:COG1647    68 WLEDVEEAYE-ILKAG--YDKVIVIGLSMGGLLALLLAARYPD-VAGLVLLSpalkiddpsapllPLLKYLARSLRGIGS 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153 270 SAKD------------------LAILQC----------------HGELDPMVPVRFGALTAEKLRSvvtpARVQFKTYPG 315
Cdd:COG1647   144 DIEDpevaeyaydrtplralaeLQRLIRevrrdlpkitaptliiQSRKDEVVPPESARYIYERLGS----PDKELVWLED 219

                         250       260
                  ....*....|....*....|....*
gi 1807916153 316 ---VMHSSCPQE--MAAVKEFLEKL 335
Cdd:COG1647   220 sghVITLDKDREevAEEILDFLERL 244
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 127-254 3.74e-03

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 39.45  E-value: 3.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1807916153  127 GAERETAAVIFLHGLGDTGHSWadalstirLPHVKYICPHAPRIPVtlnmkmvmpswfDLMG---------LSPDAPEDE 197
Cdd:PLN02980  1366 GQNAEGSVVLFLHGFLGTGEDW--------IPIMKAISGSARCISI------------DLPGhggskiqnhAKETQTEPT 1425

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1807916153  198 AGIKKAAENIKALIEHemkngIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS 254
Cdd:PLN02980  1426 LSVELVADLLYKLIEH-----ITPGKVTLVGYSMGARIALYMALRFSDKIEGAVIIS 1477
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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