MC148R [Molluscum contagiosum virus]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Chemokine super family | cl00134 | Chemokine: small cytokines, including a number of secreted growth factors and interferons ... |
28-76 | 1.58e-04 | ||
Chemokine: small cytokines, including a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; distinguished from other cytokines by their receptors, which are G-protein coupled receptors; divided into 4 subfamilies based on the arrangement of the two N-terminal cysteines; some members can bind multiple receptors and many chemokine receptors can bind more than one chemokine; this redundancy allows precise control in stimulating the immune system and in contributing to the homeostasis of a cell; when expressed inappropriately, chemokines play a role in autoimmune diseases, vascular irregularities, graft rejection, neoplasia, and allergies; exist as monomers, dimers and multimers, but are believed to function as monomers; found only in vertebrates and a few viruses. See CDs: Chemokine_CXC (cd00273), Chemokine_CC (cd00272), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for chemokine subgroups. The actual alignment was detected with superfamily member smart00199: Pssm-ID: 469625 Cd Length: 59 Bit Score: 36.45 E-value: 1.58e-04
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| Name | Accession | Description | Interval | E-value | ||
| SCY | smart00199 | Intercrine alpha family (small cytokine C-X-C) (chemokine CXC); Family of cytokines involved ... |
28-76 | 1.58e-04 | ||
Intercrine alpha family (small cytokine C-X-C) (chemokine CXC); Family of cytokines involved in cell-specific chemotaxis, mediation of cell growth, and the inflammatory response. Pssm-ID: 197570 Cd Length: 59 Bit Score: 36.45 E-value: 1.58e-04
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| IL8 | pfam00048 | Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted ... |
29-77 | 3.12e-04 | ||
Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds. Pssm-ID: 459650 Cd Length: 60 Bit Score: 35.71 E-value: 3.12e-04
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| Chemokine | cd00169 | Chemokine: small cytokines, including a number of secreted growth factors and interferons ... |
30-76 | 9.93e-04 | ||
Chemokine: small cytokines, including a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; distinguished from other cytokines by their receptors, which are G-protein coupled receptors; divided into 4 subfamilies based on the arrangement of the two N-terminal cysteines; some members can bind multiple receptors and many chemokine receptors can bind more than one chemokine; this redundancy allows precise control in stimulating the immune system and in contributing to the homeostasis of a cell; when expressed inappropriately, chemokines play a role in autoimmune diseases, vascular irregularities, graft rejection, neoplasia, and allergies; exist as monomers, dimers and multimers, but are believed to function as monomers; found only in vertebrates and a few viruses. See CDs: Chemokine_CXC (cd00273), Chemokine_CC (cd00272), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for chemokine subgroups. Pssm-ID: 238098 Cd Length: 59 Bit Score: 34.62 E-value: 9.93e-04
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| Name | Accession | Description | Interval | E-value | ||
| SCY | smart00199 | Intercrine alpha family (small cytokine C-X-C) (chemokine CXC); Family of cytokines involved ... |
28-76 | 1.58e-04 | ||
Intercrine alpha family (small cytokine C-X-C) (chemokine CXC); Family of cytokines involved in cell-specific chemotaxis, mediation of cell growth, and the inflammatory response. Pssm-ID: 197570 Cd Length: 59 Bit Score: 36.45 E-value: 1.58e-04
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| IL8 | pfam00048 | Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted ... |
29-77 | 3.12e-04 | ||
Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds. Pssm-ID: 459650 Cd Length: 60 Bit Score: 35.71 E-value: 3.12e-04
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| Chemokine | cd00169 | Chemokine: small cytokines, including a number of secreted growth factors and interferons ... |
30-76 | 9.93e-04 | ||
Chemokine: small cytokines, including a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; distinguished from other cytokines by their receptors, which are G-protein coupled receptors; divided into 4 subfamilies based on the arrangement of the two N-terminal cysteines; some members can bind multiple receptors and many chemokine receptors can bind more than one chemokine; this redundancy allows precise control in stimulating the immune system and in contributing to the homeostasis of a cell; when expressed inappropriately, chemokines play a role in autoimmune diseases, vascular irregularities, graft rejection, neoplasia, and allergies; exist as monomers, dimers and multimers, but are believed to function as monomers; found only in vertebrates and a few viruses. See CDs: Chemokine_CXC (cd00273), Chemokine_CC (cd00272), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for chemokine subgroups. Pssm-ID: 238098 Cd Length: 59 Bit Score: 34.62 E-value: 9.93e-04
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| Chemokine_CC | cd00272 | Chemokine_CC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal ... |
30-77 | 9.26e-03 | ||
Chemokine_CC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g. 2HCC) contain an additional disulfide bond which is thought to compensate for the highly conserved Trp missing in these; chemotatic for monocytes, macrophages, eosinophils, basophils, and T cells, but not neutrophils; exist as monomers and dimers, but are believed to be functional as monomers; found only in vertebrates and a few viruses; a subgroup of CC, identified by an N-terminal DCCL motif (Exodus-1, Exodus-2, and Exodus-3), has been shown to inhibit specific types of human cancer cell growth in a mouse model. See CDs: Chemokine (cd00169) for the general alignment of chemokines, or Chemokine_CXC (cd00273), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for the additional chemokine subgroups, and Chemokine_CC_DCCL for the DCCL subgroup of this CD. Pssm-ID: 238170 Cd Length: 57 Bit Score: 31.83 E-value: 9.26e-03
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