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Conserved domains on  [gi|1798208164|ref|WP_159442707|]
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glycosyltransferase family 2 protein [Porphyromonas circumdentaria]

Protein Classification

glycosyltransferase( domain architecture ID 11440269)

glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

CATH:  3.90.550.10
CAZY:  GT2
EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  9334165|16037492|12691742|10521532
SCOP:  3000077

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 7-358 2.12e-22

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


:

Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 95.58  E-value: 2.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164   7 FLAFRLLIAFLNYLFRARLPRVKDNASLPTLSVLIPARNEASNIGLILHDLIRIEGEEIREI-IVYDDASDDATPDIVSE 85
Cdd:COG1215     1 LLLLLALLALLYLLLLALARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEvIVVDDGSTDETAEIARE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  86 YMLQDERIRLLRSqglpDGWLGKNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVsllsifpcqtmyswa 165
Cdd:COG1215    81 LAAEYPRVRVIER----PENGGKAAALNAGLKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGV--------------- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 166 ekitvpnmhvillsllllpmvrrvgfssvaAANGQCMLFESRVYRALLPHLRFraSRAEDIEIARYLRKQKERVACLTGv 245
Cdd:COG1215   142 ------------------------------GASGANLAFRREALEEVGGFDED--TLGEDLDLSLRLLRAGYRIVYVPD- 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 246 ATIRCRMYDSLDSAIEGFSKNVTFFFGNSYVGAIFYWLLTTLGWVFVGISSFELLLLYLSMGLLMRLFISLTALQNVF-- 323
Cdd:COG1215   189 AVVYEEAPETLRALFRQRRRWARGGLQLLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLLLLPALLLALLLal 268

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1798208164 324 -NNIILAIPQQLMLGAFIVKSLKNKHRgyFSWKGRK 358
Cdd:COG1215   269 rRRRLLLPLLHLLYGLLLLLAALRGKK--VVWKKTP 302
 
Name Accession Description Interval E-value
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 7-358 2.12e-22

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 95.58  E-value: 2.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164   7 FLAFRLLIAFLNYLFRARLPRVKDNASLPTLSVLIPARNEASNIGLILHDLIRIEGEEIREI-IVYDDASDDATPDIVSE 85
Cdd:COG1215     1 LLLLLALLALLYLLLLALARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEvIVVDDGSTDETAEIARE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  86 YMLQDERIRLLRSqglpDGWLGKNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVsllsifpcqtmyswa 165
Cdd:COG1215    81 LAAEYPRVRVIER----PENGGKAAALNAGLKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGV--------------- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 166 ekitvpnmhvillsllllpmvrrvgfssvaAANGQCMLFESRVYRALLPHLRFraSRAEDIEIARYLRKQKERVACLTGv 245
Cdd:COG1215   142 ------------------------------GASGANLAFRREALEEVGGFDED--TLGEDLDLSLRLLRAGYRIVYVPD- 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 246 ATIRCRMYDSLDSAIEGFSKNVTFFFGNSYVGAIFYWLLTTLGWVFVGISSFELLLLYLSMGLLMRLFISLTALQNVF-- 323
Cdd:COG1215   189 AVVYEEAPETLRALFRQRRRWARGGLQLLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLLLLPALLLALLLal 268

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1798208164 324 -NNIILAIPQQLMLGAFIVKSLKNKHRgyFSWKGRK 358
Cdd:COG1215   269 rRRRLLLPLLHLLYGLLLLLAALRGKK--VVWKKTP 302
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 38-145 1.56e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 76.28  E-value: 1.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  38 SVLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYMLQDERIRLLRsqgLPDGWlGKNNACHRLAQ 117
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVV-DDGSTDGTVEIAEEYAKKDPRVRVIR---LPENR-GKAGARNAGLR 75

                          90       100
                  ....*....|....*....|....*...
gi 1798208164 118 EARGDYFLFLDADVRVAPDFINRLLAYA 145
Cdd:pfam00535  76 AATGDYIAFLDADDEVPPDWLEKLVEAL 103
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 39-154 6.88e-15

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 73.09  E-value: 6.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEG-EEIREIIVYDDASDDATPDIVsEYMLQDERIRLLRSQGLPDGWLGKNNACHRLAQ 117
Cdd:cd04192     1 VVIAARNEAENLPRLLQSLSALDYpKEKFEVILVDDHSTDGTVQIL-EFAAAKPNFQLKILNNSRVSISGKKNALTTAIK 79

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1798208164 118 EARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLLS 154
Cdd:cd04192    80 AAKGDWIVTTDADCVVPSNWLLTFVAFIQKEQIGLVA 116
PLN02726 PLN02726
dolichyl-phosphate beta-D-mannosyltransferase
 38-138 3.75e-06

dolichyl-phosphate beta-D-mannosyltransferase


Pssm-ID: 215385 [Multi-domain]  Cd Length: 243  Bit Score: 47.77  E-value: 3.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  38 SVLIPARNEASNIGLILHDLIRIEGEEIREIIVY-DDASDDATPDIVSEymLQ----DERIrLLRSQGlpdGWLGKNNA- 111
Cdd:PLN02726   12 SIIVPTYNERLNIALIVYLIFKALQDVKDFEIIVvDDGSPDGTQDVVKQ--LQkvygEDRI-LLRPRP---GKLGLGTAy 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1798208164 112 CHRLAQeARGDYFLFLDADV----RVAPDFI 138
Cdd:PLN02726   86 IHGLKH-ASGDFVVIMDADLshhpKYLPSFI 115
 
Name Accession Description Interval E-value
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 7-358 2.12e-22

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 95.58  E-value: 2.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164   7 FLAFRLLIAFLNYLFRARLPRVKDNASLPTLSVLIPARNEASNIGLILHDLIRIEGEEIREI-IVYDDASDDATPDIVSE 85
Cdd:COG1215     1 LLLLLALLALLYLLLLALARRRRAPADLPRVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEvIVVDDGSTDETAEIARE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  86 YMLQDERIRLLRSqglpDGWLGKNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVsllsifpcqtmyswa 165
Cdd:COG1215    81 LAAEYPRVRVIER----PENGGKAAALNAGLKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGV--------------- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 166 ekitvpnmhvillsllllpmvrrvgfssvaAANGQCMLFESRVYRALLPHLRFraSRAEDIEIARYLRKQKERVACLTGv 245
Cdd:COG1215   142 ------------------------------GASGANLAFRREALEEVGGFDED--TLGEDLDLSLRLLRAGYRIVYVPD- 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 246 ATIRCRMYDSLDSAIEGFSKNVTFFFGNSYVGAIFYWLLTTLGWVFVGISSFELLLLYLSMGLLMRLFISLTALQNVF-- 323
Cdd:COG1215   189 AVVYEEAPETLRALFRQRRRWARGGLQLLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLLLLPALLLALLLal 268

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1798208164 324 -NNIILAIPQQLMLGAFIVKSLKNKHRgyFSWKGRK 358
Cdd:COG1215   269 rRRRLLLPLLHLLYGLLLLLAALRGKK--VVWKKTP 302
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 35-234 4.74e-20

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 87.06  E-value: 4.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  35 PTLSVLIPARNEASNIGLILHDLIRIEGEEIREIiVYDDASDDATPDIVSEYMLQDERIRLLRSQglpdGWLGKNNACHR 114
Cdd:COG0463     2 PLVSVVIPTYNEEEYLEEALESLLAQTYPDFEII-VVDDGSTDGTAEILRELAAKDPRIRVIRLE----RNRGKGAARNA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 115 LAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLLSifpcqtMYSWAEKITVPNMHVILLSLLLLPMVRRVGFSSV 194
Cdd:COG0463    77 GLAAARGDYIAFLDADDQLDPEKLEELVAALEEGPADLVY------GSRLIREGESDLRRLGSRLFNLVRLLTNLPDSTS 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1798208164 195 AAangqcmlfesRVY-RALLPHLRFRASRAEDIEIARYLRK 234
Cdd:COG0463   151 GF----------RLFrREVLEELGFDEGFLEDTELLRALRH 181
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 38-145 1.56e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 76.28  E-value: 1.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  38 SVLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYMLQDERIRLLRsqgLPDGWlGKNNACHRLAQ 117
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVV-DDGSTDGTVEIAEEYAKKDPRVRVIR---LPENR-GKAGARNAGLR 75

                          90       100
                  ....*....|....*....|....*...
gi 1798208164 118 EARGDYFLFLDADVRVAPDFINRLLAYA 145
Cdd:pfam00535  76 AATGDYIAFLDADDEVPPDWLEKLVEAL 103
GT_2_like_e cd04192
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 39-154 6.88e-15

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133035 [Multi-domain]  Cd Length: 229  Bit Score: 73.09  E-value: 6.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEG-EEIREIIVYDDASDDATPDIVsEYMLQDERIRLLRSQGLPDGWLGKNNACHRLAQ 117
Cdd:cd04192     1 VVIAARNEAENLPRLLQSLSALDYpKEKFEVILVDDHSTDGTVQIL-EFAAAKPNFQLKILNNSRVSISGKKNALTTAIK 79

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1798208164 118 EARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLLS 154
Cdd:cd04192    80 AAKGDWIVTTDADCVVPSNWLLTFVAFIQKEQIGLVA 116
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 39-163 1.09e-14

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 70.61  E-value: 1.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYMLQDERIRLLRSQGlpdgWLGKNNACHRLAQE 118
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVV-DDGSTDGTLEILEEYAKKDPRVIRVINEE----NQGLAAARNAGLKA 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1798208164 119 ARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLLSIFPCQTMYS 163
Cdd:cd00761    76 ARGEYILFLDADDLLLPDWLERLVAELLADPEADAVGGPGNLLFR 120
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 12-144 3.34e-14

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 71.46  E-value: 3.34e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  12 LLIAFLNYLFRARlPRVKDNASLPTLSVLIPARNEASNIGLILHDLIRIEG-EEIREIIVYDDASDDATPDIVSEYmlQD 90
Cdd:cd06439     7 LLLKLLARLRPKP-PSLPDPAYLPTVTIIIPAYNEEAVIEAKLENLLALDYpRDRLEIIVVSDGSTDGTAEIAREY--AD 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1798208164  91 ERIRLLRsqglPDGWLGKNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAY 144
Cdd:cd06439    84 KGVKLLR----FPERRGKAAALNRALALATGEIVVFTDANALLDPDALRLLVRH 133
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
35-145 4.00e-13

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 67.33  E-value: 4.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  35 PTLSVLIPARNEASNIGLILHDLIRIEGEEIREIiVYDDASDDATPDIVSEymLQDERIRLLRSqglpDGWLGKNNACHR 114
Cdd:COG1216     3 PKVSVVIPTYNRPELLRRCLESLLAQTYPPFEVI-VVDNGSTDGTAELLAA--LAFPRVRVIRN----PENLGFAAARNL 75

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1798208164 115 LAQEARGDYFLFLDADVRVAPDFINRLLAYA 145
Cdd:COG1216    76 GLRAAGGDYLLFLDDDTVVEPDWLERLLAAA 106
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 38-143 3.70e-12

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 65.33  E-value: 3.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  38 SVLIPARNEASNIGLILHDLIRIEGEEIRE-IIVYDDASDDATPDIVSEYMLQDERIRLL----RSQglPDGWlgknNAC 112
Cdd:cd02525     3 SIIIPVRNEEKYIEELLESLLNQSYPKDLIeIIVVDGGSTDGTREIVQEYAAKDPRIRLIdnpkRIQ--SAGL----NIG 76

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1798208164 113 hrlAQEARGDYFLFLDADVRVAPDFINRLLA 143
Cdd:cd02525    77 ---IRNSRGDIIIRVDAHAVYPKDYILELVE 104
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 39-143 9.26e-12

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 63.02  E-value: 9.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYMLQDERIRLLRSQGLPDGwlgKNNACHRLAQE 118
Cdd:cd06423     1 IIVPAYNEEAVIERTIESLLALDYPKLEVIVV-DDGSTDDTLEILEELAALYIRRVLVVRDKENGG---KAGALNAGLRH 76

                          90       100
                  ....*....|....*....|....*
gi 1798208164 119 ARGDYFLFLDADVRVAPDFINRLLA 143
Cdd:cd06423    77 AKGDIVVVLDADTILEPDALKRLVV 101
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 35-247 1.25e-11

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 63.54  E-value: 1.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  35 PTLSVLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYM--LQDERIRLLRSQGLPdGWLGKNNAC 112
Cdd:pfam13641   2 PDVSVVVPAFNEDSVLGRVLEAILAQPYPPVEVVVV-VNPSDAETLDVAEEIAarFPDVRLRVIRNARLL-GPTGKSRGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 113 HRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVsllsiFPCQTMYSW-AEKITVPNMHVILLSLLLLPMVRRVGF 191
Cdd:pfam13641  80 NHGFRAVKSDLVVLHDDDSVLHPGTLKKYVQYFDSPKV-----GAVGTPVFSlNRSTMLSALGALEFALRHLRMMSLRLA 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1798208164 192 SSVAAANGQCMLFESRVYRALLPHLRFrASRAEDIEIARYLRKQKERVACLTGVAT 247
Cdd:pfam13641 155 LGVLPLSGAGSAIRREVLKELGLFDPF-FLLGDDKSLGRRLRRHGWRVAYAPDAAV 209
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 39-143 1.12e-10

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 59.89  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREIIVY-DDASDDATPDIVSEYMLQDERIRLLRsqgLPDGwLGKNNACHRLAQ 117
Cdd:cd04179     1 VVIPAYNEEENIPELVERLLAVLEEGYDYEIIVvDDGSTDGTAEIARELAARVPRVRVIR---LSRN-FGKGAAVRAGFK 76

                          90       100
                  ....*....|....*....|....*.
gi 1798208164 118 EARGDYFLFLDADVRVAPDFINRLLA 143
Cdd:cd04179    77 AARGDIVVTMDADLQHPPEDIPKLLE 102
GlcNAc-1-P_transferase cd06436
N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1, ...
 39-144 2.68e-10

N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine; N-acetyl-glucosamine transferase is responsible for the synthesis of bacteria Poly-beta-1,6-N-acetyl-D-glucosamine (PGA). Poly-beta-1,6-N-acetyl-D-glucosamine is a homopolymer that serves as an adhesion for the maintenance of biofilm structural stability in diverse eubacteria. N-acetyl-glucosamine transferase is the product of gene pgaC. Genetic analysis indicated that all four genes of the pgaABCD locus were required for the PGA production, pgaC being a glycosyltransferase.


Pssm-ID: 133058 [Multi-domain]  Cd Length: 191  Bit Score: 58.93  E-value: 2.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREiiVYDDASDDATPDIVSEYmLQDERIRLLRSQgLPDGWLGKNNACH----- 113
Cdd:cd06436     1 VLVPCLNEEAVIQRTLASLLRNKPNFLVL--VIDDASDDDTAGIVRLA-ITDSRVHLLRRH-LPNARTGKGDALNaaydq 76

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1798208164 114 --RLAQEARGDY----FLFLDADVRVAPDFINRLLAY 144
Cdd:cd06436    77 irQILIEEGADPerviIAVIDADGRLDPNALEAVAPY 113
DPM1_like cd06442
DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to ...
 39-143 5.46e-10

DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133062 [Multi-domain]  Cd Length: 224  Bit Score: 58.70  E-value: 5.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREIIVYDDASDDATPDIVSEYMLQDERIRLLRSQGlpDGWLGKnnACHRLAQE 118
Cdd:cd06442     1 IIIPTYNERENIPELIERLDAALKGIDYEIIVVDDNSPDGTAEIVRELAKEYPRVRLIVRPG--KRGLGS--AYIEGFKA 76

                          90       100
                  ....*....|....*....|....*
gi 1798208164 119 ARGDYFLFLDADVRVAPDFINRLLA 143
Cdd:cd06442    77 ARGDVIVVMDADLSHPPEYIPELLE 101
Glyco_transf_21 pfam13506
Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2. ...
 108-246 6.70e-09

Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80.


Pssm-ID: 433264 [Multi-domain]  Cd Length: 173  Bit Score: 54.60  E-value: 6.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 108 KNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLLSIFP-CQTMYSWAEKItvpnmhvILLSLLLLPMV 186
Cdd:pfam13506  18 KVNNLLQGLEAAKYDLLVISDSDIRVPPDYLRDLLAPLADPKVGLVTSPPvGSDPKGLAAAL-------EAAFFNTLAGV 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1798208164 187 RRVGFSSVAAANGQCMLFESRV------YRALLPHLrfrasrAEDIEIARYLRKQKERVACLTGVA 246
Cdd:pfam13506  91 LQAALSGIGFAVGMSMAFRRADleriggFEALADYL------AEDYALGKLLRAAGLKVVLSPRPI 150
GT_2_like_a cd02522
GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; ...
 37-247 9.94e-09

GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Glycosyltransferase family 2 (GT-2) subfamily of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133013 [Multi-domain]  Cd Length: 221  Bit Score: 54.88  E-value: 9.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  37 LSVLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYmlqdeRIRLLRSQglpdgwlgKNNAC--HR 114
Cdd:cd02522     1 LSIIIPTLNEAENLPRLLASLRRLNPLPLEIIVV-DGGSTDGTVAIARSA-----GVVVISSP--------KGRARqmNA 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164 115 LAQEARGDYFLFLDADVRVAPDFINRLLAYAVGKKVSLlsifpcqtmYSWAEKITVPNmhvillsllllPMVRRVGFSSV 194
Cdd:cd02522    67 GAAAARGDWLLFLHADTRLPPDWDAAIIETLRADGAVA---------GAFRLRFDDPG-----------PRLRLLELGAN 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1798208164 195 AAANG-------QCMLFESRVYRAL-----LPHLrfrasraEDIEIARYLRKQKeRVACLTGVAT 247
Cdd:cd02522   127 LRSRLfglpygdQGLFIRRELFEELggfpeLPLM-------EDVELVRRLRRRG-RPALLPSPVT 183
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 70-151 2.01e-08

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 52.95  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  70 VYDDASDDATPDIVSEYMlqdERIRLLRSQGlPDGWLGKNNAChrlAQEARGDYFLFLDADVRVAPDFINRLLAY----- 144
Cdd:cd04186    31 VVDNASTDGSVELLRELF---PEVRLIRNGE-NLGFGAGNNQG---IREAKGDYVLLLNPDTVVEPGALLELLDAaeqdp 103

                          90
                  ....*....|
gi 1798208164 145 ---AVGKKVS 151
Cdd:cd04186   104 dvgIVGPKVS 113
PLN02726 PLN02726
dolichyl-phosphate beta-D-mannosyltransferase
 38-138 3.75e-06

dolichyl-phosphate beta-D-mannosyltransferase


Pssm-ID: 215385 [Multi-domain]  Cd Length: 243  Bit Score: 47.77  E-value: 3.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  38 SVLIPARNEASNIGLILHDLIRIEGEEIREIIVY-DDASDDATPDIVSEymLQ----DERIrLLRSQGlpdGWLGKNNA- 111
Cdd:PLN02726   12 SIIVPTYNERLNIALIVYLIFKALQDVKDFEIIVvDDGSPDGTQDVVKQ--LQkvygEDRI-LLRPRP---GKLGLGTAy 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1798208164 112 CHRLAQeARGDYFLFLDADV----RVAPDFI 138
Cdd:PLN02726   86 IHGLKH-ASGDFVVIMDADLshhpKYLPSFI 115
DPG_synthase cd04188
DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate ...
 39-130 5.33e-06

DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate.


Pssm-ID: 133031 [Multi-domain]  Cd Length: 211  Bit Score: 46.79  E-value: 5.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREII---VYDDASDDATPDIVSEY-MLQDERIRLLRSqglpDGWLGKNNACHR 114
Cdd:cd04188     1 VVIPAYNEEKRLPPTLEEAVEYLEERPSFSYeiiVVDDGSKDGTAEVARKLaRKNPALIRVLTL----PKNRGKGGAVRA 76

                          90
                  ....*....|....*.
gi 1798208164 115 LAQEARGDYFLFLDAD 130
Cdd:cd04188    77 GMLAARGDYILFADAD 92
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 70-130 1.42e-05

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 45.70  E-value: 1.42e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1798208164  70 VYDDASDDATPDIVSEYMLQDERIRLLRSQGLPDGWlGKNnaCHRLAQEARGDYFLFLDAD 130
Cdd:cd04196    32 ISDDGSTDGTVEIIKEYIDKDPFIIILIRNGKNLGV-ARN--FESLLQAADGDYVFFCDQD 89
DPM1_like_bac cd04187
Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes ...
 39-174 2.86e-05

Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133030 [Multi-domain]  Cd Length: 181  Bit Score: 44.01  E-value: 2.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  39 VLIPARNEASNIGLILHDLIRIEGEEIREIIVY--DDASDDATPDIVSEYMLQDERIRLLRsqglpdgwLGKNNACHR-- 114
Cdd:cd04187     1 IVVPVYNEEENLPELYERLKAVLESLGYDYEIIfvDDGSTDRTLEILRELAARDPRVKVIR--------LSRNFGQQAal 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1798208164 115 LA--QEARGDYFLFLDADVRVAPDFINRLLA---------YAV--GKKVSLLSIFPCQTMYSWAEKITVPNMH 174
Cdd:cd04187    73 LAglDHARGDAVITMDADLQDPPELIPEMLAkweegydvvYGVrkNRKESWLKRLTSKLFYRLINKLSGVDIP 145
Glucosylceramide_synthase cd02520
Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid ...
 72-161 4.52e-05

Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment.


Pssm-ID: 133012 [Multi-domain]  Cd Length: 196  Bit Score: 43.74  E-value: 4.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  72 DDASDDATPDI---VSEYmlQDERIRLLRSQGlPDGWLGKNNACHRLAQEARGDYFLFLDADVRVAPDFINRLLAYAVGK 148
Cdd:cd02520    38 QDEDDPAIPVVrklIAKY--PNVDARLLIGGE-KVGINPKVNNLIKGYEEARYDILVISDSDISVPPDYLRRMVAPLMDP 114

                          90
                  ....*....|...
gi 1798208164 149 KVSLLSIFPCQTM 161
Cdd:cd02520   115 GVGLVTCLCAFGK 127
PTZ00260 PTZ00260
dolichyl-phosphate beta-glucosyltransferase; Provisional
 37-130 3.53e-04

dolichyl-phosphate beta-glucosyltransferase; Provisional


Pssm-ID: 240336 [Multi-domain]  Cd Length: 333  Bit Score: 42.06  E-value: 3.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  37 LSVLIPARNEASNIGLILHDLIRIEGEEIREIIVY-------DDASDDATPDIVSEYMLQDER----IRLLRSQGLpdgw 105
Cdd:PTZ00260   72 LSIVIPAYNEEDRLPKMLKETIKYLESRSRKDPKFkyeiiivNDGSKDKTLKVAKDFWRQNINpnidIRLLSLLRN---- 147

                          90       100
                  ....*....|....*....|....*
gi 1798208164 106 LGKNNACHRLAQEARGDYFLFLDAD 130
Cdd:PTZ00260  148 KGKGGAVRIGMLASRGKYILMVDAD 172
CESA_CelA_like cd06421
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of ...
 35-144 1.67e-03

CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.


Pssm-ID: 133043 [Multi-domain]  Cd Length: 234  Bit Score: 39.48  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  35 PTLSVLIPARNEASNI--GLILHDLIRIEGEEIREIIVYDDASDDATPDIVSEYMLQDERIRLLRsqglPDGWLGK---- 108
Cdd:cd06421     1 PTVDVFIPTYNEPLEIvrKTLRAALAIDYPHDKLRVYVLDDGRRPELRALAAELGVEYGYRYLTR----PDNRHAKagnl 76

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1798208164 109 NNACHRLaqeaRGDYFLFLDADVRVAPDFINRLLAY 144
Cdd:cd06421    77 NNALAHT----TGDFVAILDADHVPTPDFLRRTLGY 108
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 70-154 4.82e-03

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 37.61  E-value: 4.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  70 VYDDASDDATPDIVSEymLQDER-IRLLRsqglpdgwLGKN-------NACHRLAQEARGDYFLFLDADVRVAPDFINRL 141
Cdd:cd04185    31 VIDNASTDGTAEWLTS--LGDLDnIVYLR--------LPENlggaggfYEGVRRAYELGYDWIWLMDDDAIPDPDALEKL 100

                          90
                  ....*....|...
gi 1798208164 142 LAYAVGKKVSLLS 154
Cdd:cd04185   101 LAYADKDNPQFLA 113
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 33-146 9.61e-03

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 37.72  E-value: 9.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1798208164  33 SLPTLSVLIPARNEASNIGLILHDLIRIEGEEIREIIVyDDASDDATPDIVSEYMLQDERIRLLRSQGLpdgwlGKNNAC 112
Cdd:PRK10073    4 STPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIV-NDGSTDNSVEIAKHYAENYPHVRLLHQANA-----GVSVAR 77

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1798208164 113 HRLAQEARGDYFLFLDADVRVAPDFINRLLAYAV 146
Cdd:PRK10073   78 NTGLAVATGKYVAFPDADDVVYPTMYETLMTMAL 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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