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Conserved domains on  [gi|1796985932|gb|QHG88701|]
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TonB-dependent receptor [Xanthomonas cucurbitae]

Protein Classification

TonB-dependent receptor( domain architecture ID 1003665)

TonB-dependent receptor may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TonB-Xanth-Caul super family cl36973
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 50-1003 2.07e-173

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


The actual alignment was detected with superfamily member TIGR01782:

Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 527.67  E-value: 2.07e-173
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   50 LDTVQVSGIRGSLTSSMNVKRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSLGEGSRVTVRGVGPDFNLVLLN 129
Cdd:TIGR01782    1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  130 GRQMPgasieeSNASNSRAFDFANLASESISGIEVFKTSRASTPTGGIGATINIKTTRPLDNPGLHANVGIKGVHDAsne 209
Cdd:TIGR01782   81 GRTIA------STDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYND--- 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  210 nlpgRLQGDSLTPEISGIFSTTSADGRFGVAVTGSYQERDFGYSQVGVPNGWrafrgdstaygtipqpgapgseNIVNRP 289
Cdd:TIGR01782  152 ----LAGKDKPGPRGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWG----------------------TYTSAD 205

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  290 GPNDIYSVPQNLNYRVVGVERQRTNGQLTLQYKPLDNITTTLDYTYSENKIQQQRNEMSVWFNYGPSASAWTNGP-VAGP 368
Cdd:TIGR01782  206 GGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTaTSGA 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  369 ITYSEIVNPPTsdLATAGSNAATRaQNKSLGFNVDWAvNDQFKLNFDIHRSTAEAGPDSPYgssnslgVSGFYRGTSVVD 448
Cdd:TIGR01782  286 LVQGTVANLQI--LVEARYNEEKE-TTTSLTLGGEWT-GDRWTLDGDLGYSKATRDRPDRV-------TRFFTAPTPGYD 354

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  449 FSKDFPVlQQQLGAGLTGLDPSR----TLVTGSAFRNSYMKSE--IDQAQVNGDFtFENYSQLKFGIGSTEVKNRSAFSN 522
Cdd:TIGR01782  355 FDYRGGP-TLTLGTPADGDDASNytnpANGELRRTQISYQKAEdsEDAAQLDATF-DGPFTSLKFGVRYRRRDKTNRGSR 432

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  523 VqrdTWGGNGTAADYPDDLWIPS-TFTQYFDAINGSGNPAQFNqlflfDFERARQAAARAAGDEALYRTSPIYNTDRRVT 601
Cdd:TIGR01782  433 Y---RRSIIGATGASGLAGVPSDlAGAGLDGGLGGPLTGWDPA-----DLDAFLNAARGDAAGGGTYTYASTAPNTYTVT 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  602 EKSKNAYLQwgNSWD-DLRVpiSLAAGVRYEETKVGAQALVPVAVGIdwVANNELpirlansAFSGASGKYEYWLPSLDL 680
Cdd:TIGR01782  505 EDTTAAYAM--ANFDtGLRL--RGNVGVRYERTDQTSDGWQSQPAAN--GTGSVL-------VPVSADRDYTDVLPSLNL 571

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  681 SFKLTEDLVLRGSYGETIGRPGWGDIQGGQTLNQIARIEGGTGQEGNPGLKPLLSHNIDLSLEWYYSDASYASVGFFRKN 760
Cdd:TIGR01782  572 AYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDGTGGTVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKD 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  761 IDNYVGVTTRNDaslglntpiggaywnqalanscatadltcirnyifrnfngqpgvvrgtddangnatgVISGRPGDPVA 840
Cdd:TIGR01782  652 IKNFIVTTTSTE---------------------------------------------------------TNDGGGGLVVA 674

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  841 NFAITAPANQRSA-SLDGWEFNVQHMFGE-----SGFGVSANYTKVDSGLTY-DNAVIDEQFALEGLSD-SANVVGFYDK 912
Cdd:TIGR01782  675 GVLVSRPVNGGKAgKIRGVELGYQQTFDFlpgplSGFGVQANYTYVDSEADPsVDGVQRRKLPLPGLSKnTANATLYYEK 754

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  913 GPWQVRAAYNWRDQFLAARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLNDAVQRQHGRHPNQIVFATQTG 992
Cdd:TIGR01782  755 GGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETG 834

                          970
                   ....*....|.
gi 1796985932  993 PRYMLGLRYKF 1003
Cdd:TIGR01782  835 RTYMLGLRYKF 845
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 50-1003 2.07e-173

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 527.67  E-value: 2.07e-173
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   50 LDTVQVSGIRGSLTSSMNVKRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSLGEGSRVTVRGVGPDFNLVLLN 129
Cdd:TIGR01782    1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  130 GRQMPgasieeSNASNSRAFDFANLASESISGIEVFKTSRASTPTGGIGATINIKTTRPLDNPGLHANVGIKGVHDAsne 209
Cdd:TIGR01782   81 GRTIA------STDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYND--- 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  210 nlpgRLQGDSLTPEISGIFSTTSADGRFGVAVTGSYQERDFGYSQVGVPNGWrafrgdstaygtipqpgapgseNIVNRP 289
Cdd:TIGR01782  152 ----LAGKDKPGPRGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWG----------------------TYTSAD 205

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  290 GPNDIYSVPQNLNYRVVGVERQRTNGQLTLQYKPLDNITTTLDYTYSENKIQQQRNEMSVWFNYGPSASAWTNGP-VAGP 368
Cdd:TIGR01782  206 GGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTaTSGA 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  369 ITYSEIVNPPTsdLATAGSNAATRaQNKSLGFNVDWAvNDQFKLNFDIHRSTAEAGPDSPYgssnslgVSGFYRGTSVVD 448
Cdd:TIGR01782  286 LVQGTVANLQI--LVEARYNEEKE-TTTSLTLGGEWT-GDRWTLDGDLGYSKATRDRPDRV-------TRFFTAPTPGYD 354

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  449 FSKDFPVlQQQLGAGLTGLDPSR----TLVTGSAFRNSYMKSE--IDQAQVNGDFtFENYSQLKFGIGSTEVKNRSAFSN 522
Cdd:TIGR01782  355 FDYRGGP-TLTLGTPADGDDASNytnpANGELRRTQISYQKAEdsEDAAQLDATF-DGPFTSLKFGVRYRRRDKTNRGSR 432

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  523 VqrdTWGGNGTAADYPDDLWIPS-TFTQYFDAINGSGNPAQFNqlflfDFERARQAAARAAGDEALYRTSPIYNTDRRVT 601
Cdd:TIGR01782  433 Y---RRSIIGATGASGLAGVPSDlAGAGLDGGLGGPLTGWDPA-----DLDAFLNAARGDAAGGGTYTYASTAPNTYTVT 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  602 EKSKNAYLQwgNSWD-DLRVpiSLAAGVRYEETKVGAQALVPVAVGIdwVANNELpirlansAFSGASGKYEYWLPSLDL 680
Cdd:TIGR01782  505 EDTTAAYAM--ANFDtGLRL--RGNVGVRYERTDQTSDGWQSQPAAN--GTGSVL-------VPVSADRDYTDVLPSLNL 571

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  681 SFKLTEDLVLRGSYGETIGRPGWGDIQGGQTLNQIARIEGGTGQEGNPGLKPLLSHNIDLSLEWYYSDASYASVGFFRKN 760
Cdd:TIGR01782  572 AYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDGTGGTVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKD 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  761 IDNYVGVTTRNDaslglntpiggaywnqalanscatadltcirnyifrnfngqpgvvrgtddangnatgVISGRPGDPVA 840
Cdd:TIGR01782  652 IKNFIVTTTSTE---------------------------------------------------------TNDGGGGLVVA 674

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  841 NFAITAPANQRSA-SLDGWEFNVQHMFGE-----SGFGVSANYTKVDSGLTY-DNAVIDEQFALEGLSD-SANVVGFYDK 912
Cdd:TIGR01782  675 GVLVSRPVNGGKAgKIRGVELGYQQTFDFlpgplSGFGVQANYTYVDSEADPsVDGVQRRKLPLPGLSKnTANATLYYEK 754

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  913 GPWQVRAAYNWRDQFLAARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLNDAVQRQHGRHPNQIVFATQTG 992
Cdd:TIGR01782  755 GGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETG 834

                          970
                   ....*....|.
gi 1796985932  993 PRYMLGLRYKF 1003
Cdd:TIGR01782  835 RTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 75-1003 3.73e-45

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 173.41  E-value: 3.73e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   75 IVDGIVAEDIGKFPDTNLAESLQRISGVSIDR-SLGEGSRVTVRGVGPDFNLVLLNGRQMPGasieesnASNSRAFDFAN 153
Cdd:cd01347      1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRgGGGGGSTISIRGFGPDRTLVLVDGLPLAS-------SNYGRGVDLNT 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  154 LASESISGIEVFKTSRAS-TPTGGIGATINIKTTRPLDNPGLHANVGIkgvhdasneNLPGRLQgdsltpeisgifsttS 232
Cdd:cd01347     74 IPPELIERVEVLKGPSSAlYGSGAIGGVVNIITKRPTDEFGGSVTAGY---------GSDNSGS---------------S 129

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  233 ADGRFGVAVTGSYQErdfgysqvgvpngwrafRGDSTAYGTIPQPGApgsenivnrpgpndiysvPQNLNYRVVGVERQR 312
Cdd:cd01347    130 GGGGFDVSGALADDG-----------------AFGARLYGAYRDGDG------------------TIDGDGQADDSDEER 174

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  313 TNGQLTLQYKPLDNITTTLDYTYSENKiqqqrnemsVWFNYGPSASAWTNGPVAGPITYSeivnpPTSDLATAGSNAATR 392
Cdd:cd01347    175 YNVAGKLDWRPDDDTRLTLDAGYQDQD---------ADGPGGTLPANGTGSSLGGGPSSN-----TNGDRDWDYRDRYRK 240

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  393 AQNKSLGFNVDWAvNDQFKLNFDIHRSTAEAGPDSPYGSSNSLGVSGFYRGTSVVDFSKDFpVLQQQLGAGLTGLDPSRT 472
Cdd:cd01347    241 RASLGLEHDLNDT-GWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQL-GFDAGLNAPFGTGPVAHT 318

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  473 LVTGSAFRNsymkseidqaqvngdftfenysqlkfgigstevknrsafsnvqrdtwggngtaadypddlwipstftqyfd 552
Cdd:cd01347    319 LTLGVEYRR----------------------------------------------------------------------- 327

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  553 aingsgnpaqfnqlflfdferarqaaaraagdealyrtspiyntdRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEE 632
Cdd:cd01347    328 ---------------------------------------------EELDEKQTALYAQDTIELTD---DLTLTLGLRYDH 359

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  633 TKVGAQAlvpvavgidwvannelpirlANSAFSGASGKYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPGWGDIQGGQTL 712
Cdd:cd01347    360 YDQDSKD--------------------TIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH 419

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  713 nqiarieGGTGQEGNPGLKPLLSHNIDLSLEWYYSDASYASVGFFRKNIDNYVgvttrndaslglntpiggaywnqalAN 792
Cdd:cd01347    420 -------GGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEI-------------------------VS 467

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  793 SCATADLTCIRNYIfrnfNGQPGVVRgtddangnatgvisgrpgdpvanfaitapanqrsasldGWEFNVQHMFGEsGFG 872
Cdd:cd01347    468 TPTNTGLGLVTVYV----NGGKARIR--------------------------------------GVELEASYDLTD-GLG 504

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  873 VSANYTKVDSGLTYDNAVIDEQfALEGLS-DSANVVGFYDKGP--WQVRAAYNWRDQFLAarfDGSGQPNPVYTEAYGQL 949
Cdd:cd01347    505 LTGSYTYTDTEVKRTDGATTGN-RLPGIPkHTANLGLDYELPDegLTAGGGVRYRGKQYA---DTANGNNTVKVPGYTLV 580

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1796985932  950 DLNIGYQWNENLSLSLEAINLND-AVQRQHGRHPNQIVFATQTGPRYMLGLRYKF 1003
Cdd:cd01347    581 DLSASYQFTKNLTLRLGVNNLFDkDYYTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 431-1002 3.43e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.39  E-value: 3.43e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  431 SSNSLGVSGFYRGTSVVDFSKDFPVLQQQLGAGLTGLDPSRTLVTGSAFRNSYMKSEIDQAQVNGDFTFENYSQLKFGIG 510
Cdd:pfam00593    3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLR 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  511 STEVKNRSAFSNVQRDTWGGNGTAADYPDDLWIPSTFTQYFDA---INGSGNPAQFNQLFLFDFERARQAAARAAGDEAl 587
Cdd:pfam00593   83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPAN- 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  588 yrtsPIYNTDRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEETKVGAQALvpvavgidwvannelpirlaNSAFSGA 667
Cdd:pfam00593  162 ----PSSSSYSDTTTDSYGLYLQDNIKLTD---RLTLTLGLRYDHYSTDGDDG--------------------NGGGDNF 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  668 SGKYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPgwgdiQGGQTLNQIARIEGGTGQEGNPGLKPLLSHNIDLSLEWyYS 747
Cdd:pfam00593  215 SRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP-----SLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKY-DD 288

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  748 DASYASVGFFRKNIDNYvgvttrndaslglntpiggaywnqalanscatadltcirnyifrnfngqpgvvrgtddangna 827
Cdd:pfam00593  289 GRLSLSLALFYIDIKNL--------------------------------------------------------------- 305

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  828 tgvISGRPGDPVANFAITAPANQRSASLDGWEFNVQ-HMFGESGFGvsANYTKVDSGLTYDNAVIDEQfaLEGLSDSANV 906
Cdd:pfam00593  306 ---ITSDPDGPGLGGTVYTYTNVGKARIRGVELELSgRLWGLGLSG--GGYTYTDADDDADADDTGNP--LPNVPRHTAN 378

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  907 VGF---YDKGPWQVRAAYNWRDQflaARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLNDAVQRQHGRHPN 983
Cdd:pfam00593  379 LGLtydFPLGGWGARLGARYVGS---GERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGG 455

                          570       580
                   ....*....|....*....|
gi 1796985932  984 QIVFATQTGPR-YMLGLRYK 1002
Cdd:pfam00593  456 GNLGGYPGPGRtFYLGLSYK 475
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 20-964 3.74e-20

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 95.69  E-value: 3.74e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   20 ALSAPLAAQTAPAPQSASTvpgsSQSDPATLDTVQVSGIRGSLTssmnvKRDAQGIVDGIVAEDIGKFPDTNLAESLQRI 99
Cdd:COG4771      1 LLLASLLLLLALAAQAADA----LAEDATELEEVVVTATRTEQS-----LSDAPASVSVITAEEIEKLGATDLADALRLL 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  100 SGVSIDRSLGEG--SRVTVRGVGPDFNLVLLNGRQMpgasieeSNASNSRAFDFANLASESISGIEVFKTSrAST--PTG 175
Cdd:COG4771     72 PGVSVTRSGGRGgsSGISIRGLGGDRVLVLIDGVPV-------NNPALGGGGDLSYIPPDDIERIEVIRGP-ASAlyGSD 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  176 GIGATINIKTTRPLDNPGLHANVGIkgvhdASNENLPGRLQgdsltpeisgiFSTTSADGRFGVAVTGSYQERDfgysqv 255
Cdd:COG4771    144 AIGGVINIITKKPTDELEGSVSLGY-----GSNGNGTYSGS-----------LSLGGPGDKLSFLLSGSYRDRD------ 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  256 gvpnGWRAFRGDSTAYGTipqpgapgsenivnrpgpndiysvpqnlnyrvvgvERQRTNGQLTLQYKPLDNITTTLDYTY 335
Cdd:COG4771    202 ----GYLDYRNGGFVGNS-----------------------------------GYERYNLNAKLGYRLSDNHRLSLSGGY 242

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  336 SENKiqqqrnemsvwfnygpsasawtngpvagpITYSEIVNPPTSDLATAGSNAATRAQNKSLGFNVDWAVNDQFKLNFd 415
Cdd:COG4771    243 SRQD-----------------------------RDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLSL- 292

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  416 ihrstaeagpdspygssnslgvsgfyrgtsvvdfskdfpvlqqqlgagltgldpsrtlvtgsafrnSYMKSEIDQAQVNG 495
Cdd:COG4771    293 ------------------------------------------------------------------YYSRTDRDSTNGSL 306

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  496 DFTFENYSQLKFGIGSTEVKNRSAFSNVQRDTWGGNGTAADYpddlwipstftqyfdaingsgnpaqfnqlflfdferar 575
Cdd:COG4771    307 GGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDL-------------------------------------- 348

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  576 qaaaraagdealyrTSPIYNTDRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEetkvgaqalvpvavgidwvannel 655
Cdd:COG4771    349 --------------DSSSFLGGADASRDTYGLFAQDEWKLTD---KLTLTAGLRYD------------------------ 387

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  656 pirlaNSAFSGASGkYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPgwgdiqGGQTLNQIARIEGGTGQEGNPGLKPLLS 735
Cdd:COG4771    388 -----YYSTFGASN-YTAFSPRLGLRYDLSDNLTLRASYGRGFRAP------SLAELYGSGTGTPGRYVLGNPDLKPETS 455

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  736 HNIDLSLEWYYSDASY-ASVGFFRKNIDNYVGVTTrndaslglntpiggaywnqalanscatadltcirnyifrnfngqp 814
Cdd:COG4771    456 DNYELGLEYRLGNGGLsLSLTGFYTDIKDLIVLVP--------------------------------------------- 490

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  815 gvvrgtddangnatgvisgrpgDPVANFAITAPANQRSASLDGWEFNVQHMFGEsGFGVSANYTKVDSglTYDNAVIDEQ 894
Cdd:COG4771    491 ----------------------VGPGPGDVLQYENVGKARTYGLELELKYRLGK-GLTLTASYTYLDS--KIDDGDTGEP 545

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  895 FALEgLSDSANVVGFYDKGPWQVraAYNWRDQFLAARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLS 964
Cdd:COG4771    546 LPNV-PPHKANLGLDYRLPKWWL--LLLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
42-362 1.49e-08

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 58.87  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   42 SSQSDPATLDTVQVSGIRGSLtssmnvkRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSlGEGSRVTVRGVGP 121
Cdd:PRK13484    24 ASSDKKEDTLVVTASGFTQQL-------RNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGG-NEKPDISIRGLSG 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  122 DFNLVLLNGRQMPGasiEESNASNSRAFDFANL-ASESISGIEVFKTSRAST-PTGGIGATINIkTTRPLDNPGLHANVG 199
Cdd:PRK13484    96 DYTLILVDGRRQSG---RESRPNGSGGFEAGFIpPVEAIERIEVIRGPMSSLyGSDAIGGVINI-ITKPVNNQTWDGVLG 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  200 IKGVhdaSNENlpgRLQGDSLTPEIsgIFSTTSADGRFGVAVTGSYQERdfgysqvgvpngwrafRGDSTAYGTipqpGA 279
Cdd:PRK13484   172 LGGI---IQEH---GKFGNSTTNDF--YLSGPLIKDKLGLQLYGGMNYR----------------KEDSISQGT----PA 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  280 PGSENIVnrpgpndiysvpqnlnyrvvgverqrtngqLTLQYKPLDNITTTLDYTysenkiqqqRNEMSVWFNYGPSASA 359
Cdd:PRK13484   224 KDNKNIT------------------------------ATLQFTPTESQKFVFEYG---------KNNQVHTLTPGESLDA 264


                   ...
gi 1796985932  360 WTN 362
Cdd:PRK13484   265 WTM 267
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 50-1003 2.07e-173

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 527.67  E-value: 2.07e-173
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   50 LDTVQVSGIRGSLTSSMNVKRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSLGEGSRVTVRGVGPDFNLVLLN 129
Cdd:TIGR01782    1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  130 GRQMPgasieeSNASNSRAFDFANLASESISGIEVFKTSRASTPTGGIGATINIKTTRPLDNPGLHANVGIKGVHDAsne 209
Cdd:TIGR01782   81 GRTIA------STDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYND--- 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  210 nlpgRLQGDSLTPEISGIFSTTSADGRFGVAVTGSYQERDFGYSQVGVPNGWrafrgdstaygtipqpgapgseNIVNRP 289
Cdd:TIGR01782  152 ----LAGKDKPGPRGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWG----------------------TYTSAD 205

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  290 GPNDIYSVPQNLNYRVVGVERQRTNGQLTLQYKPLDNITTTLDYTYSENKIQQQRNEMSVWFNYGPSASAWTNGP-VAGP 368
Cdd:TIGR01782  206 GGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTaTSGA 285

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  369 ITYSEIVNPPTsdLATAGSNAATRaQNKSLGFNVDWAvNDQFKLNFDIHRSTAEAGPDSPYgssnslgVSGFYRGTSVVD 448
Cdd:TIGR01782  286 LVQGTVANLQI--LVEARYNEEKE-TTTSLTLGGEWT-GDRWTLDGDLGYSKATRDRPDRV-------TRFFTAPTPGYD 354

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  449 FSKDFPVlQQQLGAGLTGLDPSR----TLVTGSAFRNSYMKSE--IDQAQVNGDFtFENYSQLKFGIGSTEVKNRSAFSN 522
Cdd:TIGR01782  355 FDYRGGP-TLTLGTPADGDDASNytnpANGELRRTQISYQKAEdsEDAAQLDATF-DGPFTSLKFGVRYRRRDKTNRGSR 432

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  523 VqrdTWGGNGTAADYPDDLWIPS-TFTQYFDAINGSGNPAQFNqlflfDFERARQAAARAAGDEALYRTSPIYNTDRRVT 601
Cdd:TIGR01782  433 Y---RRSIIGATGASGLAGVPSDlAGAGLDGGLGGPLTGWDPA-----DLDAFLNAARGDAAGGGTYTYASTAPNTYTVT 504

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  602 EKSKNAYLQwgNSWD-DLRVpiSLAAGVRYEETKVGAQALVPVAVGIdwVANNELpirlansAFSGASGKYEYWLPSLDL 680
Cdd:TIGR01782  505 EDTTAAYAM--ANFDtGLRL--RGNVGVRYERTDQTSDGWQSQPAAN--GTGSVL-------VPVSADRDYTDVLPSLNL 571

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  681 SFKLTEDLVLRGSYGETIGRPGWGDIQGGQTLNQIARIEGGTGQEGNPGLKPLLSHNIDLSLEWYYSDASYASVGFFRKN 760
Cdd:TIGR01782  572 AYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDGTGGTVTVSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKD 651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  761 IDNYVGVTTRNDaslglntpiggaywnqalanscatadltcirnyifrnfngqpgvvrgtddangnatgVISGRPGDPVA 840
Cdd:TIGR01782  652 IKNFIVTTTSTE---------------------------------------------------------TNDGGGGLVVA 674

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  841 NFAITAPANQRSA-SLDGWEFNVQHMFGE-----SGFGVSANYTKVDSGLTY-DNAVIDEQFALEGLSD-SANVVGFYDK 912
Cdd:TIGR01782  675 GVLVSRPVNGGKAgKIRGVELGYQQTFDFlpgplSGFGVQANYTYVDSEADPsVDGVQRRKLPLPGLSKnTANATLYYEK 754

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  913 GPWQVRAAYNWRDQFLAARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLNDAVQRQHGRHPNQIVFATQTG 992
Cdd:TIGR01782  755 GGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETG 834

                          970
                   ....*....|.
gi 1796985932  993 PRYMLGLRYKF 1003
Cdd:TIGR01782  835 RTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 75-1003 3.73e-45

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 173.41  E-value: 3.73e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   75 IVDGIVAEDIGKFPDTNLAESLQRISGVSIDR-SLGEGSRVTVRGVGPDFNLVLLNGRQMPGasieesnASNSRAFDFAN 153
Cdd:cd01347      1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRgGGGGGSTISIRGFGPDRTLVLVDGLPLAS-------SNYGRGVDLNT 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  154 LASESISGIEVFKTSRAS-TPTGGIGATINIKTTRPLDNPGLHANVGIkgvhdasneNLPGRLQgdsltpeisgifsttS 232
Cdd:cd01347     74 IPPELIERVEVLKGPSSAlYGSGAIGGVVNIITKRPTDEFGGSVTAGY---------GSDNSGS---------------S 129

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  233 ADGRFGVAVTGSYQErdfgysqvgvpngwrafRGDSTAYGTIPQPGApgsenivnrpgpndiysvPQNLNYRVVGVERQR 312
Cdd:cd01347    130 GGGGFDVSGALADDG-----------------AFGARLYGAYRDGDG------------------TIDGDGQADDSDEER 174

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  313 TNGQLTLQYKPLDNITTTLDYTYSENKiqqqrnemsVWFNYGPSASAWTNGPVAGPITYSeivnpPTSDLATAGSNAATR 392
Cdd:cd01347    175 YNVAGKLDWRPDDDTRLTLDAGYQDQD---------ADGPGGTLPANGTGSSLGGGPSSN-----TNGDRDWDYRDRYRK 240

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  393 AQNKSLGFNVDWAvNDQFKLNFDIHRSTAEAGPDSPYGSSNSLGVSGFYRGTSVVDFSKDFpVLQQQLGAGLTGLDPSRT 472
Cdd:cd01347    241 RASLGLEHDLNDT-GWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQL-GFDAGLNAPFGTGPVAHT 318

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  473 LVTGSAFRNsymkseidqaqvngdftfenysqlkfgigstevknrsafsnvqrdtwggngtaadypddlwipstftqyfd 552
Cdd:cd01347    319 LTLGVEYRR----------------------------------------------------------------------- 327

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  553 aingsgnpaqfnqlflfdferarqaaaraagdealyrtspiyntdRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEE 632
Cdd:cd01347    328 ---------------------------------------------EELDEKQTALYAQDTIELTD---DLTLTLGLRYDH 359

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  633 TKVGAQAlvpvavgidwvannelpirlANSAFSGASGKYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPGWGDIQGGQTL 712
Cdd:cd01347    360 YDQDSKD--------------------TIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH 419

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  713 nqiarieGGTGQEGNPGLKPLLSHNIDLSLEWYYSDASYASVGFFRKNIDNYVgvttrndaslglntpiggaywnqalAN 792
Cdd:cd01347    420 -------GGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEI-------------------------VS 467

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  793 SCATADLTCIRNYIfrnfNGQPGVVRgtddangnatgvisgrpgdpvanfaitapanqrsasldGWEFNVQHMFGEsGFG 872
Cdd:cd01347    468 TPTNTGLGLVTVYV----NGGKARIR--------------------------------------GVELEASYDLTD-GLG 504

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  873 VSANYTKVDSGLTYDNAVIDEQfALEGLS-DSANVVGFYDKGP--WQVRAAYNWRDQFLAarfDGSGQPNPVYTEAYGQL 949
Cdd:cd01347    505 LTGSYTYTDTEVKRTDGATTGN-RLPGIPkHTANLGLDYELPDegLTAGGGVRYRGKQYA---DTANGNNTVKVPGYTLV 580

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1796985932  950 DLNIGYQWNENLSLSLEAINLND-AVQRQHGRHPNQIVFATQTGPRYMLGLRYKF 1003
Cdd:cd01347    581 DLSASYQFTKNLTLRLGVNNLFDkDYYTSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 431-1002 3.43e-22

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 101.39  E-value: 3.43e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  431 SSNSLGVSGFYRGTSVVDFSKDFPVLQQQLGAGLTGLDPSRTLVTGSAFRNSYMKSEIDQAQVNGDFTFENYSQLKFGIG 510
Cdd:pfam00593    3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLR 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  511 STEVKNRSAFSNVQRDTWGGNGTAADYPDDLWIPSTFTQYFDA---INGSGNPAQFNQLFLFDFERARQAAARAAGDEAl 587
Cdd:pfam00593   83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPAN- 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  588 yrtsPIYNTDRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEETKVGAQALvpvavgidwvannelpirlaNSAFSGA 667
Cdd:pfam00593  162 ----PSSSSYSDTTTDSYGLYLQDNIKLTD---RLTLTLGLRYDHYSTDGDDG--------------------NGGGDNF 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  668 SGKYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPgwgdiQGGQTLNQIARIEGGTGQEGNPGLKPLLSHNIDLSLEWyYS 747
Cdd:pfam00593  215 SRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP-----SLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKY-DD 288

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  748 DASYASVGFFRKNIDNYvgvttrndaslglntpiggaywnqalanscatadltcirnyifrnfngqpgvvrgtddangna 827
Cdd:pfam00593  289 GRLSLSLALFYIDIKNL--------------------------------------------------------------- 305

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  828 tgvISGRPGDPVANFAITAPANQRSASLDGWEFNVQ-HMFGESGFGvsANYTKVDSGLTYDNAVIDEQfaLEGLSDSANV 906
Cdd:pfam00593  306 ---ITSDPDGPGLGGTVYTYTNVGKARIRGVELELSgRLWGLGLSG--GGYTYTDADDDADADDTGNP--LPNVPRHTAN 378

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  907 VGF---YDKGPWQVRAAYNWRDQflaARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLNDAVQRQHGRHPN 983
Cdd:pfam00593  379 LGLtydFPLGGWGARLGARYVGS---GERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGG 455

                          570       580
                   ....*....|....*....|
gi 1796985932  984 QIVFATQTGPR-YMLGLRYK 1002
Cdd:pfam00593  456 GNLGGYPGPGRtFYLGLSYK 475
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 20-964 3.74e-20

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 95.69  E-value: 3.74e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   20 ALSAPLAAQTAPAPQSASTvpgsSQSDPATLDTVQVSGIRGSLTssmnvKRDAQGIVDGIVAEDIGKFPDTNLAESLQRI 99
Cdd:COG4771      1 LLLASLLLLLALAAQAADA----LAEDATELEEVVVTATRTEQS-----LSDAPASVSVITAEEIEKLGATDLADALRLL 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  100 SGVSIDRSLGEG--SRVTVRGVGPDFNLVLLNGRQMpgasieeSNASNSRAFDFANLASESISGIEVFKTSrAST--PTG 175
Cdd:COG4771     72 PGVSVTRSGGRGgsSGISIRGLGGDRVLVLIDGVPV-------NNPALGGGGDLSYIPPDDIERIEVIRGP-ASAlyGSD 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  176 GIGATINIKTTRPLDNPGLHANVGIkgvhdASNENLPGRLQgdsltpeisgiFSTTSADGRFGVAVTGSYQERDfgysqv 255
Cdd:COG4771    144 AIGGVINIITKKPTDELEGSVSLGY-----GSNGNGTYSGS-----------LSLGGPGDKLSFLLSGSYRDRD------ 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  256 gvpnGWRAFRGDSTAYGTipqpgapgsenivnrpgpndiysvpqnlnyrvvgvERQRTNGQLTLQYKPLDNITTTLDYTY 335
Cdd:COG4771    202 ----GYLDYRNGGFVGNS-----------------------------------GYERYNLNAKLGYRLSDNHRLSLSGGY 242

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  336 SENKiqqqrnemsvwfnygpsasawtngpvagpITYSEIVNPPTSDLATAGSNAATRAQNKSLGFNVDWAVNDQFKLNFd 415
Cdd:COG4771    243 SRQD-----------------------------RDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGDNLDLSL- 292

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  416 ihrstaeagpdspygssnslgvsgfyrgtsvvdfskdfpvlqqqlgagltgldpsrtlvtgsafrnSYMKSEIDQAQVNG 495
Cdd:COG4771    293 ------------------------------------------------------------------YYSRTDRDSTNGSL 306

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  496 DFTFENYSQLKFGIGSTEVKNRSAFSNVQRDTWGGNGTAADYpddlwipstftqyfdaingsgnpaqfnqlflfdferar 575
Cdd:COG4771    307 GGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDL-------------------------------------- 348

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  576 qaaaraagdealyrTSPIYNTDRRVTEKSKNAYLQWGNSWDDlrvPISLAAGVRYEetkvgaqalvpvavgidwvannel 655
Cdd:COG4771    349 --------------DSSSFLGGADASRDTYGLFAQDEWKLTD---KLTLTAGLRYD------------------------ 387

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  656 pirlaNSAFSGASGkYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPgwgdiqGGQTLNQIARIEGGTGQEGNPGLKPLLS 735
Cdd:COG4771    388 -----YYSTFGASN-YTAFSPRLGLRYDLSDNLTLRASYGRGFRAP------SLAELYGSGTGTPGRYVLGNPDLKPETS 455

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  736 HNIDLSLEWYYSDASY-ASVGFFRKNIDNYVGVTTrndaslglntpiggaywnqalanscatadltcirnyifrnfngqp 814
Cdd:COG4771    456 DNYELGLEYRLGNGGLsLSLTGFYTDIKDLIVLVP--------------------------------------------- 490

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  815 gvvrgtddangnatgvisgrpgDPVANFAITAPANQRSASLDGWEFNVQHMFGEsGFGVSANYTKVDSglTYDNAVIDEQ 894
Cdd:COG4771    491 ----------------------VGPGPGDVLQYENVGKARTYGLELELKYRLGK-GLTLTASYTYLDS--KIDDGDTGEP 545

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  895 FALEgLSDSANVVGFYDKGPWQVraAYNWRDQFLAARFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLS 964
Cdd:COG4771    546 LPNV-PPHKANLGLDYRLPKWWL--LLLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
50-972 1.07e-15

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 81.80  E-value: 1.07e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   50 LDTVQVSGirgslTSSMNVKRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSLGEGSRVTVRGVGPDFN--LVL 127
Cdd:COG1629      1 LEEVVVTA-----TRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNrvLVL 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  128 LNGRQMPGASieeSNASNSRAFDfanlaSESISGIEVFKTSRASTP-TGGIGATINIKTTRPLDNPGLHANVGIKGVHDA 206
Cdd:COG1629     76 VDGVPLNDPS---GGDGGLSYID-----PEDIERVEVLRGPSSALYgSGALGGVINIVTKKPKDGKGGEVSASYGSYGTY 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  207 SNEnlpgrlqgdsltpeisgiFSTTSADGRFGVAVTGSYQERDfgysqvgvpnGWRafrgDSTAYgtipqpgapgseniv 286
Cdd:COG1629    148 RAS------------------LSLSGGNGKLAYRLSASYRDSD----------GYR----DNSDS--------------- 180

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  287 nrpgpndiysvpqnlnyrvvgverQRTNGQLTLQYKPLDNITTTLDYTYSenKIQQQRNEMSVWFNYGPSASAWtngpva 366
Cdd:COG1629    181 ------------------------DRYNLRAKLGYQLGDDTRLTLSASYS--DSDQDSPGYLTLAALRPRGAMD------ 228

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  367 gpityseivnpptsDLATAGSNAATRAQNKSLGFNVDW-AVNDQFKLNfdihrstaeagpdspygssnslgvSGFYRGTS 445
Cdd:COG1629    229 --------------DGTNPYSNDTDDNTRDRYSLSLEYeHLGDGLKLS------------------------ASAYYRYD 270

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  446 VVDFSKDFPVLQQQLGAGLTGLDPSRTLVTgsafrnsymkseidQAQVNGDFTFENYSQLKFGIgstevknrsafsNVQR 525
Cdd:COG1629    271 DTDLDSDFTPTPADGGTLEQTDFDNRTYGL--------------ELRLTYDLGFGGKHTLLVGL------------DYQR 324

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  526 DTWGGNGTAADYPDDLWIPSTFTQYFDaingsgnpaqfnqlflfdferarqaaaraagdealyrtspiyntdrrVTEKSK 605
Cdd:COG1629    325 QDLDGSGYPLDLGSGSLPTLTSGADDD-----------------------------------------------GTTTSL 357

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  606 NAYLQWGNSWDDlrvPISLAAGVRYEETKVGAQALVPVAVGIDwvannelpirlANSAFSGasgkyeyWLPSLDLSFKLT 685
Cdd:COG1629    358 ALYAQDTYKLTD---KLTLTAGLRYDYVSYDVDDTVTGTDSAS-----------GSRSYSA-------FSPSLGLTYQLS 416

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  686 EDLVLRGSYGETIGRPGWGDIQGGQTlnqiariegGTGQEGNPGLKPLLSHNIDLSLEWYYSDASY-ASVGFFRKNIDNY 764
Cdd:COG1629    417 PNLSLYASYSRGFRAPTFGELYANGT---------DPYSVGNPDLKPETSTNYELGLRYRLLDGRLsLSLALFYSDVDNE 487

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  765 vgvttrndaslglntpiggaywnqalanscatadltcIRNYIFRNFNGQPGVVRgtddangnatgvisgrpgdpvanfai 844
Cdd:COG1629    488 -------------------------------------ILSVPLPNDSGFSTYYT-------------------------- 504

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  845 tapaNQRSASLDGWEFNVQHMFGEsGFGVSANYTKVDSglTYDNAViDEQFALEGLS------DSANVVGFYD-KGPWQV 917
Cdd:COG1629    505 ----NAGKARSYGVELELSYQLTP-GLSLNASYSYTDA--KFDDDT-DGSADLDGNRlpgvppLTANLGLTYEfPGGWSL 576

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1796985932  918 RAAYNWRDqflaaRFDGSGQPNPVYTEAYGQLDLNIGYQWNENLSLSLEAINLND 972
Cdd:COG1629    577 GLGVRYVG-----DRYLDDANTQGAPGGYTLVDLGAGYRFGDNLTLSLGVDNLFD 626
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
53-339 5.62e-15

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 76.45  E-value: 5.62e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   53 VQVSGIRGSLTssmnvKRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRS--LGEGSRVTVRGVGPDFNLVLLNG 130
Cdd:COG4206      1 VVVTATRLEQS-----KSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSggPGSAASISIRGLGSNQTLVLIDG 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  131 RQMpgasieesNASNSRAFDFANLASESISGIEVFKTSRASTP-TGGIGATINIKTTRPLDNPGLHANVGIkGVHDASNE 209
Cdd:COG4206     76 VPL--------NDPSLGGVDLSLIPPDDIERIEVLKGAASALYgSDAIGGVINITTKKGKKGFKGSVSASY-GSFGTRRL 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  210 NLpgrlqgdsltpeisgifSTTSADGRFGVAVTGSYQERDfGYSQVGVPNGWRAFRGDSTAYGTIPQPGAPGSeNIVNRP 289
Cdd:COG4206    147 SA-----------------SLSGGAGKFSYSLSASYRRSD-GYRYNDPDLRNNDGYENTSLNARLGYKLGDNG-SLSLSG 207

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1796985932  290 GPNDiysvpQNLNYRVVGVERQRTNGQLTLQYKPLDNITTTLDYTYSENK 339
Cdd:COG4206    208 GYSD-----SERGYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDR 252
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 69-180 1.18e-14

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 70.76  E-value: 1.18e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   69 KRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSI-DRSLGEGSRVTVRGVGPDFNLVLLNGRQMpgasieesNASNSR 147
Cdd:pfam07715    2 LRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVsSGGGGGGSSISIRGFGSNRVLVLVDGVPL--------NSGGGG 73

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1796985932  148 AFDFANLASESISGIEVFKTsrASTPTGGIGAT 180
Cdd:pfam07715   74 SVDLNSIDPEDIERVEVLKG--PASALYGSGAI 104
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
36-1003 1.53e-09

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 61.87  E-value: 1.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   36 ASTVPGSSQSDPATLDTVQVSGIRGSLTSSMNVKrdaqGIVDGIVAEDIGKFPDTNLAESLQRISGVSI-DRS-LGEGSR 113
Cdd:COG4772      9 LLLAAAAAAEAATTLETVVVTGSRAAEARLKDVP----GSVSVVDREELENQAATSLREVLRRVPGVNVqEEDgFGLRPN 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  114 VTVRGVGPDFN---LVLLNGRQMPGASIEESNASNSrafdfanLASESISGIEVFKTSRASTP----TGGIgatINIKTT 186
Cdd:COG4772     85 IGIRGLGPRRSrgiTLLEDGIPIAPAPYGDPAAYYF-------PDLERMERIEVLRGAAALRYgpqtVGGA---INFVTR 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  187 RPLDNPGLHANVgikgvhdasnenlpgRLQGDSLTpeiSGIFSTTSADGRFGVAVTGSYQERDfgysqvgvpnGWRafrg 266
Cdd:COG4772    155 TIPTAFGGELRV---------------TGGSFGYR---RTHASVGGTVGNFGYLVEYSRKRGD----------GFR---- 202

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  267 DSTAYgtipqpgapgsenivnrpgpndiysvpqnlnyrvvgverQRTNGQLTLQYKPLDNITTTLDYTYSENKIQQqrne 346
Cdd:COG4772    203 DNSGF---------------------------------------DINDFNAKLGYRLSDRQELTLKFQYYDEDANT---- 239

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  347 msvwfnygpsasawtngpvAGPITYSEIVNPPTSdlaTAGSNAATRAQNKSLGFNVDWAVNDQFKLNFdihrstaeagpd 426
Cdd:COG4772    240 -------------------PGGLTDAQFDADPRQ---SYRPADQFDTRRTQLSLRYEHQLSDNTTLTT------------ 285

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  427 spygssnslgvsGFYRGTSvvdfskdfpvlqqqlgagltgldpsrtlvtgsaFRNSYMKSEIDQAQVNGDFTFENysqlk 506
Cdd:COG4772    286 ------------TAYYNDF---------------------------------SRNWYIRQNTADPNTPGLGLRGN----- 315

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  507 fgigstevkNRsafsnvQRDTWGGNgTAADYPDDLW-IPSTFTQYFDAINGSGNPAQFNqlflfdferarqaaaraaGDE 585
Cdd:COG4772    316 ---------PR------GYRSYGIE-PRLTHRFELGgVPHTLEVGLRYHREEEDRKQYV------------------NTY 361

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  586 ALYRTSPIYNTDRRVTEKSKNAYLQwgNSWDdLRVPISLAAGVRYEETKVGAQALVPVAVGIDwvannelpirlansafS 665
Cdd:COG4772    362 GQGRSGAGLRRDRRFSADALAAYAQ--NRFE-LTGRLTLTPGLRYEHIRRDRTDRYSTRTGGD----------------D 422

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  666 GASGKYEYWLPSLDLSFKLTEDLVLRGSYGETIGRPGWGDIqggqtlnqiariegGTGQEGNPGLKPLLSHNIDLSLEWY 745
Cdd:COG4772    423 SGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDL--------------AYGNGGNPDLKPEKSWNYELGTRGR 488

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  746 YSDASYASVGFFRKNIDNYVGVTTRNDASLGLNTPIGGAywnqalanscatadltcirnyifrnfngqpgVVRGTDdang 825
Cdd:COG4772    489 IGNGLSAEVALFYIDYDNELGSCSAAGGDRSTFTNAGET-------------------------------RHQGLE---- 533

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  826 natgvisgrpgdpvanfaitapanqrsASLDgWEFNVQHMFGesgFGVSANYTKVDSglTYDNAViDEQFA---LEGLSD 902
Cdd:COG4772    534 ---------------------------LALD-YDLLKGGGLG---LPLFAAYTYTDA--EFTSDF-GPVFAgnrLPYVPR 579

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  903 SANVVGF-YDKGPWQVRAAYNWRDQFLA----ARFDGSGQPNPvyteAYGQLDLNIGYQWNENLSLSLEAINLND----- 972
Cdd:COG4772    580 HQLTAGLgYEHGGWTANLNGRYVSEQFTdaanTVADGSFGKIP----SYTVLDLSASYDFGKNLSLFAGVNNLFDkryia 655

                          970       980       990
                   ....*....|....*....|....*....|....
gi 1796985932  973 --AVQRQHGRHPNQivfatqtgPR-YMLGLRYKF 1003
Cdd:COG4772    656 srAPNYAAGIRPGP--------PRtVYAGLRLKF 681
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
42-362 1.49e-08

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 58.87  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   42 SSQSDPATLDTVQVSGIRGSLtssmnvkRDAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSlGEGSRVTVRGVGP 121
Cdd:PRK13484    24 ASSDKKEDTLVVTASGFTQQL-------RNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGG-NEKPDISIRGLSG 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  122 DFNLVLLNGRQMPGasiEESNASNSRAFDFANL-ASESISGIEVFKTSRAST-PTGGIGATINIkTTRPLDNPGLHANVG 199
Cdd:PRK13484    96 DYTLILVDGRRQSG---RESRPNGSGGFEAGFIpPVEAIERIEVIRGPMSSLyGSDAIGGVINI-ITKPVNNQTWDGVLG 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  200 IKGVhdaSNENlpgRLQGDSLTPEIsgIFSTTSADGRFGVAVTGSYQERdfgysqvgvpngwrafRGDSTAYGTipqpGA 279
Cdd:PRK13484   172 LGGI---IQEH---GKFGNSTTNDF--YLSGPLIKDKLGLQLYGGMNYR----------------KEDSISQGT----PA 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  280 PGSENIVnrpgpndiysvpqnlnyrvvgverqrtngqLTLQYKPLDNITTTLDYTysenkiqqqRNEMSVWFNYGPSASA 359
Cdd:PRK13484   224 KDNKNIT------------------------------ATLQFTPTESQKFVFEYG---------KNNQVHTLTPGESLDA 264


                   ...
gi 1796985932  360 WTN 362
Cdd:PRK13484   265 WTM 267
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 21-236 5.25e-07

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 53.61  E-value: 5.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   21 LSAPLAAQTAPAPQSASTVPGSSQSDPATLDTVQVSGirgslTSSMNVKRdaQGIVDGIVAEDIGKFPDTN-LAESLQRI 99
Cdd:PRK13528     5 VNKILWLLTVLLVGLNSPVSAAESSDDDNGETMVVEA-----TAEQELKQ--QPGVSIITAEDIKKRPPVNdLSDIIRKM 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  100 SGVSIDRSLGEGSR-----VTVRGVGPDFNLVLLNGRqmPGASieeSNA--------SNSRAfDFANLASESISGIEVFK 166
Cdd:PRK13528    78 PGVNLTGNSASGTRgnnrqIDIRGMGPENTLILIDGV--PVTS---RNSvryswrgeRDTRG-DTNWVPPEMVERIEVIR 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  167 -TSRASTPTGGIGATINIKTTRPLDNPglHANVGI---------KGVHDASNENLPGRLQGDSLTPEISGIFSTTSADGR 236
Cdd:PRK13528   152 gPAAARYGSGAAGGVVNIITKRPTNDW--HGSLSLytnqpesskEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSW 229
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 15-358 7.94e-07

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 52.97  E-value: 7.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   15 SALLFALSApLAAQTAPAPQSASTvpgSSQSDPATLDTVQVSGIRGSlTSSMNVKRDAQG---------------IVDGI 79
Cdd:COG4773      1 AAALLAGSG-LAAAAAGALAQAAA---AAAAEATTLPEVTVTGTAEG-TGGYTAKSSSTAtkldtplretpqsvsVVTRQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   80 VAEDIGkfpDTNLAESLQRISGVSIDRSLGEG-SRVTVRGVGPDFnlVLLNGRQMPGasieesnaSNSRAFDFANLASes 158
Cdd:COG4773     76 LIEDQG---ATTLDDALRNVPGVTVSSYDGGGrDSFSIRGFSIDN--YLRDGLPLGG--------FGGGQPDTANLER-- 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  159 isgIEVFK-TSRASTPTGGIGATINIKTTRPLDNPGLHANVGikgvhdASNENLpGRLQGDsltpeISGIFsttSADGRF 237
Cdd:COG4773    141 ---VEVLKgPAGLLYGAGSPGGLVNLVTKRPTAEPQGEVSLS------AGSWDT-YRATAD-----VGGPL---NEDGTL 202

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  238 GVAVTGSYQE----RDFGYSQVGVPNG---WRAfrGDST------AYGTIPQPGAPGSenivnRPGPNDIYSVP--QNLN 302
Cdd:COG4773    203 RYRLNAAYEDgdsfRDGVDNRRTLIAPsldWDL--TDDTtltlgaEYQDDDSTGDRGF-----LPLDGTLLDLPrsTNLG 275

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1796985932  303 YRVVGVERQRTNGQLTLQYKPLDNITTTLDYTYSENKiqqqRNEMSVWFNYGPSAS 358
Cdd:COG4773    276 EPWDYYDTETTTLFAELEHRFNDDWSLRANARYSDSD----RDGRSAYAYGAPDAA 327
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
82-200 1.04e-04

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 46.14  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   82 EDIGKFPDTNLAESLQRISGVSIDRS--LGEGSRVTVRGVGPDFNLVLLNGRQMPGASIeeSNASnsrafDFANLASESI 159
Cdd:PRK10641    52 DDIDRWQSKSVNDVLRRLPGVDIAQNggLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGI--SGSA-----DLSQIPISLV 124

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1796985932  160 SGIEVFKTSR-ASTPTGGIGATINIKTTRplDNPGLHANVGI 200
Cdd:PRK10641   125 QRIEYIRGPRsAVYGSDAIGGVVNIITTR--DKPGTTLSAGW 164
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
 607-781 1.66e-04

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 45.34  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  607 AYLQWGNSWDDLrvpiSLAAGVRYEETKVGAqalvpvavgiDWVANNELPIRlansafsgasgKYEYWLPSLDLSFKLTE 686
Cdd:pfam14905  117 AYASYSKKFGKW----SYQAGLRAEYTDIDG----------DSVTTNETFKR-----------NYFNLFPSASLSYKLND 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  687 D--LVLRGSYGETIGRPGWGDiqggqtLNQIARIEGGTG-QEGNPGLKPLLSHNIDL--SLEWYYSdasyASVGFFRKNI 761
Cdd:pfam14905  172 NnsLQLSLYYRRIINRPSYWD------LNPFRNYSDPYNySQGNPNLKPEYTNSFELgyTYKWKLS----LSLSYRYTND 241

                          170       180
                   ....*....|....*....|
gi 1796985932  762 DNYVGVTTRNDASLGLNTPI 781
Cdd:pfam14905  242 VIQQTFITDDNDNVTYTTYE 261
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
11-234 4.97e-04

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 44.25  E-value: 4.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   11 RRLTSALLFaLSAPLAAQTAPAPQSASTvpgSSQSDPATLDTVQVSGIRGSltssmnvkRDAQGiVDGIVAEDIGKFPDT 90
Cdd:PRK13524     3 KKIHSLALL-VNLGIYGVAQAAEAEDAK---TDDTPASHEDTIVVTAAEQN--------LQAPG-VSTITAEDIRKRPPA 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   91 N-LAESLQRISGVSIDRSLGEGSR-----VTVRGVGPDFNLVLLNGRQM-------PGASIEEsnasNSRAfDFANLASE 157
Cdd:PRK13524    70 NdVSEIIRTMPGVNLTGNSTSGQRgnnrqIDIRGMGPENTLILIDGKPVssrnsvrYGWRGER----DTRG-DTNWVPPE 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  158 SISGIEVFK-TSRASTPTGGIGATINIKTTRPLDNpgLHANVGI---------KGVHDASNENLPGRLqGDSLTPEISGI 227
Cdd:PRK13524   145 MIERIEVLRgPAAARYGNGAAGGVVNIITKKPTGE--WHGSWNTyfnapehkaEGATKRTNFSLSGPL-GDELSFRLYGN 221


                   ....*..
gi 1796985932  228 FSTTSAD 234
Cdd:PRK13524   222 LNKTQAD 228
PRK13486 PRK13486
TonB-dependent receptor;
41-360 2.19e-03

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 41.93  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932   41 GSSQSDPATLDTVQV---SGIRGSLTSsmnvkrdAQGIVDGIVAEDIGKFPDTNLAESLQRISGVSIDRSLGE--GSRVT 115
Cdd:PRK13486    15 GFSASSIAAAEDVMIvsaSGYEKKLTN-------AAASVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGKtgGLEIS 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  116 VRGVGPDFNLVLLNGRQMPGASIEESNASNSRAFDFANLASeSISGIEVFKtSRASTPTG--GIGATINIKTTRPLDNPG 193
Cdd:PRK13486    88 IRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLA-AIERIEVIR-GPMSTLYGsdAMGGVVNIITRKNADKWL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  194 LHANVGIKgvHDASNEnlpgrlQGDSLTPEISGifSTTSADGRFGVAVTGSYQERDfGYSQVGVPNgwrafrgdsTAYGT 273
Cdd:PRK13486   166 SSVNAGLN--LQESNK------WGNSSQFNFWS--SGPLVDDSVSLQVRGSTQQRQ-GSSVTSLSD---------TAATR 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1796985932  274 IPQPGAPGSENIVNRPgpnDIYSVPQNLNYRVVGVERQR---TNGQltlqykpLDNITTTLDYTysenkIQQQRNEMSVW 350
Cdd:PRK13486   226 IPYPTESQNYNLGARL---DWKASEQDVLWFDMDTTRQRydnRDGQ-------LGSLTGGYDRT-----LRYERNKISAG 290

                          330
                   ....*....|
gi 1796985932  351 FNYGPSASAW 360
Cdd:PRK13486   291 YDHTFTFGTW 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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