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Conserved domains on  [gi|1787414364|ref|WP_157843974|]
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lipopolysaccharide assembly protein LapB [Epibacterium ulvae]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 56-243 5.01e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 5.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  56 QIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEI-TEAQLGLGALELSRN 134
Cdd:COG2956    45 HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAEL 214
Cdd:COG2956   125 DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERA 204

                         170       180
                  ....*....|....*....|....*....
gi 1787414364 215 ASSQINDVTVRQNLAISYYIIGRKELALD 243
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALE 233
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 56-243 5.01e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 5.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  56 QIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEI-TEAQLGLGALELSRN 134
Cdd:COG2956    45 HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAEL 214
Cdd:COG2956   125 DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERA 204

                         170       180
                  ....*....|....*....|....*....
gi 1787414364 215 ASSQINDVTVRQNLAISYYIIGRKELALD 243
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALE 233
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 44-194 1.10e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.64  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  44 DFLGSQPVGYQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEA 122
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdPELGRA 433

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1787414364 123 QLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNL 194
Cdd:TIGR02917 434 DLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL 505
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 64-208 1.26e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 41.98  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  64 LQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALELSRNNAGKAMRI 142
Cdd:NF040959   48 AKKGRYDKAVRYLEQVARIDPDDVEALYRLGVAYLKTGQYDRAIKVLEKVLSLApDHVKAAYRKGVALLKIKDYEKAVED 127

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1787414364 143 FANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGA 208
Cdd:NF040959  128 LEEALEEKPDNFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIKYHQAIGFMYVQKGDHETAA 193
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 54-218 2.18e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 39.30  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364   54 QSQIQLAENFLQAGDFDRAynlfdQVDEANSRSAKVQL---------------ALGRAYFRQNAFLKAERAFDNA----- 113
Cdd:PRK11447   260 EQQKQLADPAFRARAQGLA-----AVDSGQGGKAIPELqqavranpkdsealgALGQAYSQQGDRARAVAQFEKAlaldp 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  114 --------SGLGEITEAQLGL--GALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKI 183
Cdd:PRK11447   335 hssnrdkwESLLKVNRYWLLIqqGDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRM 414

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1787414364  184 DPGHVDAANNLgLSLTLSGSAESGASILAELASSQ 218
Cdd:PRK11447   415 DPGNTNAVRGL-ANLYRQQSPEKALAFIASLSASQ 448
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 56-243 5.01e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 5.01e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  56 QIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEI-TEAQLGLGALELSRN 134
Cdd:COG2956    45 HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAEL 214
Cdd:COG2956   125 DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERA 204

                         170       180
                  ....*....|....*....|....*....
gi 1787414364 215 ASSQINDVTVRQNLAISYYIIGRKELALD 243
Cdd:COG2956   205 LEQDPDYLPALPRLAELYEKLGDPEEALE 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 53-246 3.33e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.70  E-value: 3.33e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  53 YQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQLGLGALEL 131
Cdd:COG2956    76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLgPENAHAYCELAELYL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 132 SRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASIL 211
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELL 235

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1787414364 212 AELASSQiNDVTVRQNLAISYYIIGRKELALDIAS 246
Cdd:COG2956   236 RKALELD-PSDDLLLALADLLERKEGLEAALALLE 269
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 55-244 1.39e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.46  E-value: 1.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  55 SQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQLGLGALELSR 133
Cdd:COG2956    10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERdPDRAEALLELAQDYLKA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 134 NNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAE 213
Cdd:COG2956    90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1787414364 214 LASSQINDVTVRQNLAISYYIIGRKELALDI 244
Cdd:COG2956   170 ALKLDPDCARALLLLAELYLEQGDYEEAIAA 200
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
53-266 1.67e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.19  E-value: 1.67e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  53 YQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALEL 131
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLALQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 132 SRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASIL 211
Cdd:COG0457    88 ALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELL 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1787414364 212 AELASSQINDVTVRQNLAISYYIIGRKELALDIASINFKKTEALALFEAVSNYRL 266
Cdd:COG0457   168 EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAEL 222
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 46-214 1.04e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.29  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  46 LGSQPVGYQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQL 124
Cdd:COG2956   103 LELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLdPDCARALL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 125 GLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGhVDAANNLGLSLTLSGSA 204
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGL 261

                         170
                  ....*....|
gi 1787414364 205 ESGASILAEL 214
Cdd:COG2956   262 EAALALLERQ 271
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 54-187 7.78e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 7.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  54 QSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQLGLGALELS 132
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELdPDEPEARLNLGLALLK 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1787414364 133 RNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGH 187
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 53-245 1.74e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 1.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  53 YQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALE-- 130
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAal 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 131 --------LSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSG 202
Cdd:COG3914    81 lelaalllQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1787414364 203 SAESGASILAELASSQINDVTVRQNLAISYYIIGRKELALDIA 245
Cdd:COG3914   161 RLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY 203
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 56-228 4.11e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 4.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  56 QIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALELSRN 134
Cdd:COG3914    47 LLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNpDNAEALFNLGNLLLALG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAEL 214
Cdd:COG3914   127 RLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRA 206

                         170
                  ....*....|....
gi 1787414364 215 ASSQINDVTVRQNL 228
Cdd:COG3914   207 LELDPDNADAHSNL 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 44-194 1.10e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.64  E-value: 1.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  44 DFLGSQPVGYQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEA 122
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdPELGRA 433

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1787414364 123 QLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNL 194
Cdd:TIGR02917 434 DLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL 505
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 121-243 2.94e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.12  E-value: 2.94e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 121 EAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTL 200
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1787414364 201 SGSAESGASILAELASSQINDVTVRQNLAISYYIIGRKELALD 243
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-194 1.95e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 1.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  55 SQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRN 134
Cdd:TIGR02917 671 AQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLASG 750

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNL 194
Cdd:TIGR02917 751 NTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNL 810
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 138-244 5.42e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 5.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 138 KAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELASS 217
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100
                  ....*....|....*....|....*..
gi 1787414364 218 QINDVTVRQNLAISYYIIGRKELALDI 244
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAA 107
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
58-245 6.26e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 52.32  E-value: 6.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  58 QLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQLGLGALELSRNNA 136
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELdPDDAEALYNLGLALLELGRY 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 137 GKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELAS 216
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         170       180
                  ....*....|....*....|....*....
gi 1787414364 217 SQINDVTVRQNLAISYYIIGRKELALDIA 245
Cdd:COG0457   207 LRKKLAILTLAALAELLLLALALLLALRL 235
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 59-198 1.01e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 1.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  59 LAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLAL-GRAYFRQNAFLKAERAFDNASGLGE-ITEAQLGLGALELSRNNA 136
Cdd:TIGR02917  96 LARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALrGLAYLGLGQLELAQKSYEQALAIDPrSLYAKLGLAQLALAENRF 175

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1787414364 137 GKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSL 198
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATIL 237
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 84-216 1.04e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  84 SRSAKVQLALGRAYFRQNAFLKAERAFDNASGL-GEITEAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGV 162
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELdPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1787414364 163 AHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELAS 216
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
82-243 1.15e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.07  E-value: 1.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  82 ANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIG 161
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 162 VAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELASSQINDVTVRQNLAISYYIIGRKELA 241
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELA 160


                  ..
gi 1787414364 242 LD 243
Cdd:COG4785   161 IA 162
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
59-198 2.01e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.30  E-value: 2.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  59 LAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNNAGK 138
Cdd:COG4785    12 LALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDL 91

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 139 AMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSL 198
Cdd:COG4785    92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 104-244 2.50e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.19  E-value: 2.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 104 LKAERAFDNASGLGEITEAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKI 183
Cdd:COG5010     4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1787414364 184 DPGHVDAANNLGLSLTLSGSAESGASILAELASSQINDVTVRQNLAISYYIIGRKELALDI 244
Cdd:COG5010    84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 54-191 9.37e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 9.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  54 QSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNAsglgeiteaqlglgalelsr 133
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERA-------------------- 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1787414364 134 nnagkamrifaniLVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAA 191
Cdd:COG4235    78 -------------LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR 122
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
147-243 1.03e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 147 LVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELASSQINDVTVRQ 226
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90
                  ....*....|....*..
gi 1787414364 227 NLAISYYIIGRKELALD 243
Cdd:COG0457    81 NLGLALQALGRYEEALE 97
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 123-268 1.27e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 123 QLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSG 202
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1787414364 203 SAESGASILAELASSQINDVTVRQNLAISYYIIGRKELALDIAS--INFKKTEALALFEAVSNYRLSG 268
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLErlLKLGPENAHAYCELAELYLEQG 158
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 121-202 1.47e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 121 EAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTL 200
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97


                  ..
gi 1787414364 201 SG 202
Cdd:COG4235    98 QG 99
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 70-213 4.20e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  70 DRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNNAGKAMRIFANILVE 149
Cdd:COG5010     4 LEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1787414364 150 DPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAE 213
Cdd:COG5010    84 DPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
58-149 9.49e-06

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 45.64  E-value: 9.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  58 QLAENFLQAGDFDRAYNLFDQVDEANS--RSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNN 135
Cdd:COG4700   129 GLAQALFELGRYAEALETLEKLIAKNPdfKSSDAHLLYARALEALGDLEAAEAELEALARRYSGPEARYRYAKFLARQGR 208

                          90
                  ....*....|....
gi 1787414364 136 AGKAMRIFANILVE 149
Cdd:COG4700   209 TAEAKELLEEILDE 222
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 62-157 3.91e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 3.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  62 NFLQAGDFDRAYNLFDQVDEANSRS---AKVQLALGRAYFRQNAFLKAERAFDNASGLG----EITEAQLGLGALELSRN 134
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYpdspKAPDALLKLGLSYLELG 81

                          90       100
                  ....*....|....*....|...
gi 1787414364 135 NAGKAMRIFANILVEDPENLRAQ 157
Cdd:COG1729    82 DYDKARATLEELIKKYPDSEAAK 104
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 47-241 5.13e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 5.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  47 GSQPVGYQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAF---------------- 110
Cdd:TIGR02917 561 ELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFkkllalqpdsalalll 640

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 111 ---------DNASGLGEI----------TEAQLGLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHY 171
Cdd:TIGR02917 641 ladayavmkNYAKAITSLkralelkpdnTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYP 720

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 172 LAQVAYRNALKIDPGHvDAANNLGLSLTLSGSAESGASILAELASSQINDVTVRQNLAISYYIIGRKELA 241
Cdd:TIGR02917 721 AAIQAYRKALKRAPSS-QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKA 789
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 59-266 5.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 5.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  59 LAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALELSRNNAG 137
Cdd:TIGR02917 437 LILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEpDFFPAAANLARIDIQEGNPD 516

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 138 KAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELASS 217
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADA 596

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1787414364 218 QINDVTVRQNLAISYYIIGRKELALDiasiNFKKTEALALFEAVSNYRL 266
Cdd:TIGR02917 597 APDSPEAWLMLGRAQLAAGDLNKAVS----SFKKLLALQPDSALALLLL 641
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-241 6.08e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 6.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  55 SQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGE---------ITEAQLG 125
Cdd:TIGR02917  58 ARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLDDegaaellalRGLAYLG 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 126 LGALELSRNNagkamriFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAE 205
Cdd:TIGR02917 138 LGQLELAQKS-------YEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIE 210

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1787414364 206 SGASILAELASSQINDVTVRQNLAISYYIIGRKELA 241
Cdd:TIGR02917 211 LALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA 246
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 64-208 1.26e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 41.98  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  64 LQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALELSRNNAGKAMRI 142
Cdd:NF040959   48 AKKGRYDKAVRYLEQVARIDPDDVEALYRLGVAYLKTGQYDRAIKVLEKVLSLApDHVKAAYRKGVALLKIKDYEKAVED 127

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1787414364 143 FANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGA 208
Cdd:NF040959  128 LEEALEEKPDNFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIKYHQAIGFMYVQKGDHETAA 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
131-218 1.44e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 131 LSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQvAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASI 210
Cdd:COG3063     3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81


                  ....*...
gi 1787414364 211 LAELASSQ 218
Cdd:COG3063    82 LERALELD 89
BamD COG4105
Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope ...
 26-112 1.83e-04

Outer membrane protein assembly factor BamD, BamD/ComL family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443281 [Multi-domain]  Cd Length: 254  Bit Score: 41.79  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  26 RALMVAFMAAASTLLHGC----DFLGSQPVgyQSQIQLAENFLQAGDFDRAYNLFDQVDEA---NSRSAKVQLALGRAYF 98
Cdd:COG4105     3 KLLKLLLLLLLALLLAGCssfkKALKSWDA--EELYEEAKEALEKGDYEKAIKLFEELEPRypgSPYAEQAQLMLAYAYY 80

                          90
                  ....*....|....
gi 1787414364  99 RQNAFLKAERAFDN 112
Cdd:COG4105    81 KQGDYEEAIAAADR 94
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
163-243 2.07e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 2.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 163 AHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESgASILAELASSQINDVTVRQNLAISYYIIGRKELAL 242
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE-AIALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                  .
gi 1787414364 243 D 243
Cdd:COG3063    80 A 80
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
63-155 2.81e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 2.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  63 FLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNNAGKAMRI 142
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                          90
                  ....*....|...
gi 1787414364 143 FANILVEDPENLR 155
Cdd:COG3063    82 LERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 56-150 2.92e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  56 QIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEITEAQLGLGALELSRNN 135
Cdd:COG2956   181 LLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEG 260

                          90
                  ....*....|....*
gi 1787414364 136 AGKAMRIFANILVED 150
Cdd:COG2956   261 LEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 152-244 4.86e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.40  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 152 ENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELASSQINDVTVRQNLAIS 231
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90
                  ....*....|...
gi 1787414364 232 YYIIGRKELALDI 244
Cdd:COG4783    82 LLKAGDYDEALAL 94
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
96-185 5.15e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 5.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  96 AYFRQNAFLKAERAFDNASGLG-EITEAQLGLGALELSRNNAGKAMRiFANILVEDPENLRAQNGIGVAHDLNGDHYLAQ 174
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDpDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|.
gi 1787414364 175 VAYRNALKIDP 185
Cdd:COG3063    80 AYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 58-243 5.60e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 5.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  58 QLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLGEIT-EAQLGLGALELSRNNA 136
Cdd:TIGR02917 538 ALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSpEAWLMLGRAQLAAGDL 617

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364 137 GKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDPGHVDAANNLGLSLTLSGSAESGASILAELAS 216
Cdd:TIGR02917 618 NKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQK 697

                         170       180
                  ....*....|....*....|....*..
gi 1787414364 217 SQINDVTVRQNLAISYYIIGRKELALD 243
Cdd:TIGR02917 698 QHPKAALGFELEGDLYLRQKDYPAAIQ 724
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 46-185 1.11e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  46 LGSQPVGYQSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFLKAERAFDNASGLG-EITEAQL 124
Cdd:COG5010    13 YLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDpNNPELYY 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1787414364 125 GLGALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKIDP 185
Cdd:COG5010    93 NLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 64-182 1.90e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 38.30  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  64 LQAGDFDRAYNLFDQVDEANSRSAKVQLA---LGRAYFRQNAFLKAERAFDNA------SGLGEIteAQLGLGALELSRN 134
Cdd:COG2976    64 LAAGDAAAAAAAAEKLIDDYGGTAYAALAallLAKAAVDAGDLDKAAAQLQWVldnakdPALKAL--ARLRLARVLLAQK 141

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1787414364 135 NAGKAMRIFANIlveDPENLRAQngigvAHDLNGDHYLAQ-------VAYRNALK 182
Cdd:COG2976   142 KYDEALATLDAV---KPEAFAAL-----YAELRGDILLAQgdkaearAAYQKALA 188
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 54-218 2.18e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 39.30  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364   54 QSQIQLAENFLQAGDFDRAynlfdQVDEANSRSAKVQL---------------ALGRAYFRQNAFLKAERAFDNA----- 113
Cdd:PRK11447   260 EQQKQLADPAFRARAQGLA-----AVDSGQGGKAIPELqqavranpkdsealgALGQAYSQQGDRARAVAQFEKAlaldp 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  114 --------SGLGEITEAQLGL--GALELSRNNAGKAMRIFANILVEDPENLRAQNGIGVAHDLNGDHYLAQVAYRNALKI 183
Cdd:PRK11447   335 hssnrdkwESLLKVNRYWLLIqqGDAALKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRM 414

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1787414364  184 DPGHVDAANNLgLSLTLSGSAESGASILAELASSQ 218
Cdd:PRK11447   415 DPGNTNAVRGL-ANLYRQQSPEKALAFIASLSASQ 448
OM_YfiO TIGR03302
outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a ...
 27-111 8.21e-03

outer membrane assembly lipoprotein YfiO; Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274513 [Multi-domain]  Cd Length: 235  Bit Score: 36.76  E-value: 8.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  27 ALMVAFMAAASTLLHGCDFLGSQPVGYQSQ------IQLAENFLQAGDFDRAYNLFDQVDE---ANSRSAKVQLALGRAY 97
Cdd:TIGR03302   1 LLLLILLLALLLLLAGCSSKKKKEADPVEEwpaeelYEEAKEALDSGDYTEAIKYFEALESrypFSPYAEQAQLDLAYAY 80

                          90
                  ....*....|....
gi 1787414364  98 FRQNAFLKAERAFD 111
Cdd:TIGR03302  81 YKSGDYAEAIAAAD 94
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 54-183 8.84e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 37.10  E-value: 8.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787414364  54 QSQIQLAENFLQAGDFDRAYNLFDQVDEANSRSAKVQLALGRAYFRQNAFlkaERAFDNASGLGEITEAQLG-------- 125
Cdd:PRK11788  108 LALQELGQDYLKAGLLDRAEELFLQLVDEGDFAEGALQQLLEIYQQEKDW---QKAIDVAERLEKLGGDSLRveiahfyc 184

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1787414364 126 -LGALELSRNNAGKAMRIFANILVEDPENLRAqnGIgvahdLNGDHYLAQVAYRNALKI 183
Cdd:PRK11788  185 eLAQQALARGDLDAARALLKKALAADPQCVRA--SI-----LLGDLALAQGDYAAAIEA 236
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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