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Conserved domains on  [gi|1787161323|gb|QGZ55343|]
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ABC transporter permease subunit [Paraburkholderia acidiphila]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
13-308 4.36e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.36e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  13 TPATRRASPMAALADRWIPKLVLSPSILISLFFVYGFILVTGYLSLSTSRLM-PRYEFAGLDRYRELFANDVWWTSAQNL 91
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  92 GWFGIPFIAICVALGLFLAILLDQQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLG-IQQVMHSIGWTSFqlDWLN 170
Cdd:COG1175    82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 171 NPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDL 250
Cdd:COG1175   160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1787161323 251 VVALTAGGPGTSSSLPAIFMYTFSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRS 308
Cdd:COG1175   240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
13-308 4.36e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.36e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  13 TPATRRASPMAALADRWIPKLVLSPSILISLFFVYGFILVTGYLSLSTSRLM-PRYEFAGLDRYRELFANDVWWTSAQNL 91
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  92 GWFGIPFIAICVALGLFLAILLDQQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLG-IQQVMHSIGWTSFqlDWLN 170
Cdd:COG1175    82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 171 NPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDL 250
Cdd:COG1175   160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1787161323 251 VVALTAGGPGTSSSLPAIFMYTFSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRS 308
Cdd:COG1175   240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
33-307 1.44e-19

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 86.42  E-value: 1.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  33 LVLSPSILISLFFvygFILVTG-YLSLSTSRLMP---RYEFAGLDRYRELFANDVWWTSAqnlgWFGIPFIAICVALG-- 106
Cdd:PRK10561    1 LLVAPQLIITVIF---FIWPAGeALWYSLQSVDPfgfSSQFVGLDNFVALFHDSYYLDSF----WTTIKFSTLVTVSGll 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 107 --LFLAILLDQQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLGIqqVMHSIGWTSFQLDWLNNPDRAIFCIVVAAV 184
Cdd:PRK10561   74 vsLFFAALVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGL--ITHFLAEFGYDWNHAQNSGQAMFLVVFASV 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 185 WQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLI-LCHITIKTFDLVVALTAGGPGTSS 263
Cdd:PRK10561  152 WKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQAT 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1787161323 264 SLPAIFMYTFSFNRGQLGVGAASS-MMMLATVVAVLVPLMYLESR 307
Cdd:PRK10561  232 TTLIYKIYREGFTGLDLSSSAAQSvVLMFLVIVLTVVQFRYVESK 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-295 3.19e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 43.81  E-value: 3.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  93 WFGIPFIAICVALGLFLAILLDQQIRQ-EGALRAVFLYPMALSYIVTGTAWQWIFnpdlgiqqvmhsigwtSFQLDWLNN 171
Cdd:cd06261     6 LLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVLGLLLVLLF----------------GVLLGWGIL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 172 PDRAIFCIVVAAVWqSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDLV 251
Cdd:cd06261    70 PGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1787161323 252 VALTAGGPGTSSSLpaIFMYTFSFNRGQLGVGAASSMMMLATVV 295
Cdd:cd06261   149 SFLGGGEAPGPGTG--LLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 164-299 9.35e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 42.29  E-value: 9.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 164 FQLDWLNNPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHI 243
Cdd:pfam00528  40 VVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1787161323 244 TIKTFDLVVALTAGGPGTSSSLPAIFMYTFSFnrGQLGVGAASSMMMLATVVAVLV 299
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPE--IQGPVLAAALILLLLNLLVDIL 173
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
13-308 4.36e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.36e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  13 TPATRRASPMAALADRWIPKLVLSPSILISLFFVYGFILVTGYLSLSTSRLM-PRYEFAGLDRYRELFANDVWWTSAQNL 91
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  92 GWFGIPFIAICVALGLFLAILLDQQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLG-IQQVMHSIGWTSFqlDWLN 170
Cdd:COG1175    82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 171 NPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDL 250
Cdd:COG1175   160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1787161323 251 VVALTAGGPGTSSSLPAIFMYTFSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRS 308
Cdd:COG1175   240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
33-307 1.44e-19

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 86.42  E-value: 1.44e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  33 LVLSPSILISLFFvygFILVTG-YLSLSTSRLMP---RYEFAGLDRYRELFANDVWWTSAqnlgWFGIPFIAICVALG-- 106
Cdd:PRK10561    1 LLVAPQLIITVIF---FIWPAGeALWYSLQSVDPfgfSSQFVGLDNFVALFHDSYYLDSF----WTTIKFSTLVTVSGll 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 107 --LFLAILLDQQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLGIqqVMHSIGWTSFQLDWLNNPDRAIFCIVVAAV 184
Cdd:PRK10561   74 vsLFFAALVDYVVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGL--ITHFLAEFGYDWNHAQNSGQAMFLVVFASV 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 185 WQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLI-LCHITIKTFDLVVALTAGGPGTSS 263
Cdd:PRK10561  152 WKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQAT 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1787161323 264 SLPAIFMYTFSFNRGQLGVGAASS-MMMLATVVAVLVPLMYLESR 307
Cdd:PRK10561  232 TTLIYKIYREGFTGLDLSSSAAQSvVLMFLVIVLTVVQFRYVESK 276
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 68-240 1.92e-16

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 78.21  E-value: 1.92e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  68 EFAGLDRYRELFANDVWWTSAQNLGWFGIPFIAICVALGLFLAILLDQqIRQEGALRAV----FLyPMALSYIVTGTAWQ 143
Cdd:COG4209    68 PWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILALLLNE-LRSKRFKKTVqtisYL-PHFLSWVVVAGIVY 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 144 WIFNPDLG-IQQVMHSIGWTSFqlDWLNNPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYR 222
Cdd:COG4209   146 QFLSPDTGlVNQLLRALGGEPI--NFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIW 223

                         170
                  ....*....|....*...
gi 1787161323 223 KIVIPSMRPVfFSVLLIL 240
Cdd:COG4209   224 HITLPGIRPT-IVILLIL 240
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 23-310 3.73e-15

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 74.03  E-value: 3.73e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  23 AALADRWIPKLVLSPS-ILISLFFVYGFILVTGYlSLSTSRLMPRYEFA-GLDRYRELFANDVWWTSAQNLGWFGIPFIA 100
Cdd:COG1176     3 AALRRRLRPLLLLLPAlLWLLLFFVLPLLLLLVY-SFTTRDPYGGVVPGfTLENYARLFTDPLYLKVLLRTLWIALLTTL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 101 ICVALGLFLAILLDQ-QIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLGIQQVMHSIGWTSFQLDWLNNPdraiFCI 179
Cdd:COG1176    82 ICLLLGYPIAYFLARaPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTE----FAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 180 VVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLilchitiktfdLVVALTAG-- 257
Cdd:COG1176   158 VIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSL-----------LVFIPALGaf 226

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1787161323 258 ------GPGTSSSLpAIFMYTFSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRSTR 310
Cdd:COG1176   227 vtpallGGGKVLMI-GNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRL 284
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 28-312 6.93e-13

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 67.44  E-value: 6.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  28 RWIPKLVLSPSILISLFFVYGFILVTGYLSLSTSRLmPRYEFAG--LDRYRELFANDVWWTSAQNLGWFGIPFIAICVAL 105
Cdd:COG1177     2 SRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWF-LTFPPEGftLRWYAELFSDPRLLDALLNSLLIALLSTLLATVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 106 GLFLAILLDQ-QIRQEGALRAVFLYPMALSYIVTGtawqwifnpdLGIQQVMHSIGWTsfqldwlnnpdRAIFCIVVAAV 184
Cdd:COG1177    81 GTPAALALARyRFRGRRLLLALLLLPLVVPGIVLG----------VALLLLFSALGLS-----------GGLWGLILAHV 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 185 WQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILchITIKTFDLVVALTAGGPGTsSS 264
Cdd:COG1177   140 VFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLA--FTLSFDEFVITLFLAGPGV-TT 216

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1787161323 265 LPaIFMYTfSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRSTRNA 312
Cdd:COG1177   217 LP-VYIYS-MIRRGISPEINALSTLLILLSLLLLLLAERLRRRGERRR 262
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
22-307 3.31e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 63.64  E-value: 3.31e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  22 MAALADRWIPKLVLSPSILISLFFVY--GFILVTGYlslstsrlmpryeFAGLDRYRELFANDVWWTSAQNLGWFGIPFI 99
Cdd:COG1178     1 MSTRPRRRPRLLLLLLALLLALLVLLplLALLLRAF-------------TDGLANFWALLSDPYLWRALGNTLLLALLVT 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 100 AICVALGLFLAILLDQ-QIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLGIQQVMHSI-GWTSFQLdwlnnpdRAIF 177
Cdd:COG1178    68 LLSLLLGVPLAWLLARtDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALfGLEPPDI-------YGLG 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 178 CIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDLVVALtag 257
Cdd:COG1178   141 GIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--- 217

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1787161323 258 gpGTSSSLPAIFMYTFSFNRGQLGVGAASSMMMLATVVAVLVPLMYLESR 307
Cdd:COG1178   218 --GGGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRR 265
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
16-308 1.07e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 59.02  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  16 TRRASPMAALADRWIPKLVLspsILISLFFVYGFILVTGYLSLSTSRLMPRYEFaGLDRYRELFANDVWWTSAQNLGWFG 95
Cdd:COG1178   272 GGRARRPRRVKLGRWRWLAL---ALCLLLVLLGLLLPLLALLLWSLTKALDDNL-TLDNYRFVLLDPSLLRALLNSLLLA 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  96 IPFIAICVALGLFLAILLD-QQIRQEGALRAVFLYPMALSYIVTGTAWQWIFNPDLGIqqvmhSIGWTSFQLdwlnnpdr 174
Cdd:COG1178   348 LLAALLAVLLALLLAYLVRrRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPL-----LLYGTLAIL-------- 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 175 aIFCIVVAAVwqstGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDLVVAL 254
Cdd:COG1178   415 -VLAYVVRFL----PFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLL 489

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1787161323 255 tagGPGTSSSLPaIFMYTFsFNRGQLGVGAASSMMMLATVVAVLVPLMYLESRS 308
Cdd:COG1178   490 ---RPPGFETLA-VLIYQL-ASSGRYGEAAALALLLVLVSLLPVLLLERLLGRR 538
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-295 3.19e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 43.81  E-value: 3.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  93 WFGIPFIAICVALGLFLAILLDQQIRQ-EGALRAVFLYPMALSYIVTGTAWQWIFnpdlgiqqvmhsigwtSFQLDWLNN 171
Cdd:cd06261     6 LLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVLGLLLVLLF----------------GVLLGWGIL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 172 PDRAIFCIVVAAVWqSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHITIKTFDLV 251
Cdd:cd06261    70 PGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALV 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1787161323 252 VALTAGGPGTSSSLpaIFMYTFSFNRGQLGVGAASSMMMLATVV 295
Cdd:cd06261   149 SFLGGGEAPGPGTG--LLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 164-299 9.35e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 42.29  E-value: 9.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 164 FQLDWLNNPDRAIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILCHI 243
Cdd:pfam00528  40 VVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1787161323 244 TIKTFDLVVALTAGGPGTSSSLPAIFMYTFSFnrGQLGVGAASSMMMLATVVAVLV 299
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPE--IQGPVLAAALILLLLNLLVDIL 173
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 165-239 9.54e-04

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 40.08  E-value: 9.54e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1787161323 165 QLDWLNNpdraIFCIVVAAVWQSTGFCMALFLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLI 239
Cdd:COG0395   137 QLGLLNT----YWGLILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIF 207
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 39-269 1.02e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 40.22  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323  39 ILISLFFVYGFILVTGYLSLSTSRLMPRYEFAGLDRYRELFANDVWWTSAQNLGWFGIPFIAICVALGLFLAILLDQQIR 118
Cdd:PRK10592   16 LVLGFTFLYAPMLMLVIYSFNSSKLVTVWAGWSTRWYGELFRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVMVRFGR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1787161323 119 QEGALRAVFLY--PMALSYIVTGTAWQWIFnpdlgiQQVMHSIGWTSfqldwlnnpDRAIFCIVVAAVWQSTGFCMALFL 196
Cdd:PRK10592   96 FRGSNGFAFMItaPLVMPDVITGLSLLLLF------VALAHAIGWPA---------DRGMLTIWLAHVTFCTAYVAVVIS 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1787161323 197 AGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVLLILchITIKTFDLVVALTAGGPGTSSSLPAIF 269
Cdd:PRK10592  161 SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLA--FTLSLDDLVIASFVSGPGATTLPMLVF 231
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 175-237 8.49e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 37.05  E-value: 8.49e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1787161323 175 AIFCIVVAAVWQstgfcMAL-FLAGLRGVDSEIFKAAQVDGATLPTIYRKIVIPSMRPVFFSVL 237
Cdd:COG0600   128 KIFVIFLGAFFP-----ILLnTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGL 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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