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Conserved domains on  [gi|1786814647|gb|KAF0187413|]
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gamma-glutamyltranspeptidase [Caulobacteraceae bacterium]

Protein Classification

gamma-glutamyltransferase family protein( domain architecture ID 10001375)

gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond

CATH:  3.60.20.40
Gene Ontology:  GO:0016787
SCOP:  4000420

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
53-584 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


:

Pssm-ID: 440174  Cd Length: 507  Bit Score: 643.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  53 AAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLDLETLRr 132
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYL- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 133 vareKGGGYIPSFGAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQRRLERafaerql 212
Cdd:COG0405    80 ----DAGDEIPVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAAERLAR------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 213 eeIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWVDPLC 292
Cdd:COG0405   149 --DPGAAAIFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAAGGLLTLEDLAAYRAEWREPLS 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 293 VDYRaGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLIAPGY 372
Cdd:COG0405   227 GTYR-GYTVYSMPPPSQGIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAY 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 373 ADQRRAMIRMDRAMDTPDAG-PDVLRRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRGELFALTDGHA 451
Cdd:COG0405   306 AAERAALIDPDRATPSPRPGdPTGPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVPGTGFLLNNRGDDFSLDPGHP 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 452 NIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHGDDAeptgeppqdkG 531
Cdd:COG0405   386 NALAPGKRPRSTMSPTIVLKDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRWHHQGLP----------D 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1786814647 532 KVFLETGFTPAVREALRARGHDVRPGDGSFGGYQAIMRDAeRGVYVAATEMRK 584
Cdd:COG0405   456 TLELEPRFPPAVIAALRARGHKVEVVPDWSGGAQAILRDP-DGVLEGAADPRR 507
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
53-584 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 643.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  53 AAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLDLETLRr 132
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYL- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 133 vareKGGGYIPSFGAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQRRLERafaerql 212
Cdd:COG0405    80 ----DAGDEIPVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAAERLAR------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 213 eeIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWVDPLC 292
Cdd:COG0405   149 --DPGAAAIFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAAGGLLTLEDLAAYRAEWREPLS 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 293 VDYRaGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLIAPGY 372
Cdd:COG0405   227 GTYR-GYTVYSMPPPSQGIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAY 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 373 ADQRRAMIRMDRAMDTPDAG-PDVLRRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRGELFALTDGHA 451
Cdd:COG0405   306 AAERAALIDPDRATPSPRPGdPTGPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVPGTGFLLNNRGDDFSLDPGHP 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 452 NIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHGDDAeptgeppqdkG 531
Cdd:COG0405   386 NALAPGKRPRSTMSPTIVLKDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRWHHQGLP----------D 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1786814647 532 KVFLETGFTPAVREALRARGHDVRPGDGSFGGYQAIMRDAeRGVYVAATEMRK 584
Cdd:COG0405   456 TLELEPRFPPAVIAALRARGHKVEVVPDWSGGAQAILRDP-DGVLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
66-586 3.93e-159

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 464.76  E-value: 3.93e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  66 IDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLDLETLRRvareKGGGYIPSF 145
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDG----KGDSKLSLT 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 146 GAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQRRLERAfaerqleeiENARRTYWPN 225
Cdd:pfam01019  77 GGLAVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAEERLRAD---------PGLRKIFLPT 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 226 GVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWVDPLCVDYRaGVSLCELP 305
Cdd:pfam01019 148 GRVLKAGELLKQPALAKTLELIAEEGPDAFYRGELAQQLVADLQANGGIITAEDLANYRVKIREPLSADYG-GYTVYSPP 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 306 PNTQGVSALQMLQILRGYDMRAlGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLIAPGYADQRRAMIRMDRA 385
Cdd:pfam01019 227 PSSGGIALLQILNILEGFDLSS-LLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLINPNAA 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 386 MDTPDAGPDvlrrGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRG--------ELFALTDGHANIYAPR 457
Cdd:pfam01019 306 FPSSYAPED----GGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTGILLNNEMddfstppgNAFGLDPSPANAIAPG 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 458 KRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHgddaeptgeppQDKGKVFLET 537
Cdd:pfam01019 382 KRPLSSMAPTIVLDDGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHH-----------QLPDVLEVEP 450
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1786814647 538 GFTPAVREALRARGHDVRPGDGSFGGYQAIMRDAERGVYVAATEMRKDG 586
Cdd:pfam01019 451 GFPEEVLAELEARGHKVKVVEDSSSVGAIQIVRRTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
52-579 1.49e-106

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 330.19  E-value: 1.49e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  52 GAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGldleTLR 131
Cdd:TIGR00066   1 GMVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAK----ATR 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 132 RVAREKGGGYIPSFGAA---AVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQrrlerafa 208
Cdd:TIGR00066  77 DMFLDKSGNPLPGKSLTgglAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTLELYE-------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 209 ERQLEEIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWV 288
Cdd:TIGR00066 149 EVLLTTKEDSKDIFNPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQKNGGIMTKKDLAAYDVEIR 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 289 DPLCVDYRAGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLI 368
Cdd:TIGR00066 229 KPLSGDYRGYQVYTTPPPSSGGIHLLQALNILENFDLSQYGDGSAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEELL 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 369 APGYADQRRAMIRMDRAMDTPDAGPDVLR---RGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRGELFA 445
Cdd:TIGR00066 309 DKRYAKELAQSIKINKVDPKSTIYPGAYQpneGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTGILLNNEMDDFS 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 446 LTDGHANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHGDDAEptge 525
Cdd:TIGR00066 389 LKPGGANAVEPNKRPLSSMAPTIVLKDGKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIHHQWLPD---- 464
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1786814647 526 ppqdkgKVFLETGFTPAVREALRARGHDVR-PGDGSFGGYQAIMRDAERGVYVAA 579
Cdd:TIGR00066 465 ------ELRLEKGFPDDVLQLLKDMGHKVTlKEVFPMGVVQAIRVDPEGWLYGVS 513
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
46-591 7.38e-60

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 209.38  E-value: 7.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  46 PVIAPHGAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVwdpRTKklhgyngSGRSpQGL 125
Cdd:PRK09615   44 PVRAKQGMVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLL---RTK-------NGNT-TAI 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 126 DLetlRRVAREKGGG--YIPSFGAA----------AVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIA 193
Cdd:PRK09615  113 DF---REMAPAKATRdmFLDDQGNPdskksltshlASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALA 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 194 FYWannqrrleRAFAERQLEEIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGG 273
Cdd:PRK09615  190 DDL--------KTYGSEVLPNHENSKAIFWKEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKNGG 261
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 274 WLRYEDFVAHHGEWVDPLCVDYRAGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKY 353
Cdd:PRK09615  262 LITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEY 341
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 354 FADPAFALADLNRLIAPGYADQRRAMIRMDRAMDTPDAGPDVL---RRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVP 430
Cdd:PRK09615  342 LGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLapyESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVA 421
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 431 DGLGFMLQDRGELFA----------LTDGHANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVD 500
Cdd:PRK09615  422 GNSGILLNNQMDDFSakpgvpnvygLVGGDANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSID 501
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 501 YGLDVQAAGDAARWRHgddaeptgEPPQDKGKVflETGFTPAVREALRARGHDVRPGDgSFGGYQAIMRDAERGVYVAAT 580
Cdd:PRK09615  502 YGMNVAEATNAPRFHH--------QWLPDELRV--EKGFSPDTLKLLEAKGQKVALKE-AMGSTQSIMVGPDGELYGASD 570
                         570
                  ....*....|.
gi 1786814647 581 EMRKDGAADGY 591
Cdd:PRK09615  571 PRSVDDLTAGY 581
 
Name Accession Description Interval E-value
Ggt COG0405
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
53-584 0e+00

Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];


Pssm-ID: 440174  Cd Length: 507  Bit Score: 643.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  53 AAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLDLETLRr 132
Cdd:COG0405     1 MVATAHPLASQAGLEILRAGGNAVDAAVAAAAALAVVEPHSSGIGGGGFALIYDAKDGKVTALDGRGTAPAAATPDMYL- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 133 vareKGGGYIPSFGAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQRRLERafaerql 212
Cdd:COG0405    80 ----DAGDEIPVRGPLAVGVPGTVAGWEAAHERYGTLPLAELLAPAIRLAEDGFPVSPRLAALLAAAAERLAR------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 213 eeIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWVDPLC 292
Cdd:COG0405   149 --DPGAAAIFLPDGRPPKAGDILRQPDLAATLRRIAEEGADAFYRGEIAEAIVAAVQAAGGLLTLEDLAAYRAEWREPLS 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 293 VDYRaGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLIAPGY 372
Cdd:COG0405   227 GTYR-GYTVYSMPPPSQGIALLQILNILEGFDLAALGPDSAEYVHLLAEAMKLAFADRDRYLGDPDFVDVPVEGLLSPAY 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 373 ADQRRAMIRMDRAMDTPDAG-PDVLRRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRGELFALTDGHA 451
Cdd:COG0405   306 AAERAALIDPDRATPSPRPGdPTGPESGDTTHLSVVDRDGNAVSLTQSIYGGFGSGVVVPGTGFLLNNRGDDFSLDPGHP 385
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 452 NIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHGDDAeptgeppqdkG 531
Cdd:COG0405   386 NALAPGKRPRSTMSPTIVLKDGKPVLVFGSPGGSRIPQTVLQVLLNVLDFGMNPQEAVDAPRWHHQGLP----------D 455
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1786814647 532 KVFLETGFTPAVREALRARGHDVRPGDGSFGGYQAIMRDAeRGVYVAATEMRK 584
Cdd:COG0405   456 TLELEPRFPPAVIAALRARGHKVEVVPDWSGGAQAILRDP-DGVLEGAADPRR 507
G_glu_transpept pfam01019
Gamma-glutamyltranspeptidase;
66-586 3.93e-159

Gamma-glutamyltranspeptidase;


Pssm-ID: 425991  Cd Length: 499  Bit Score: 464.76  E-value: 3.93e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  66 IDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLDLETLRRvareKGGGYIPSF 145
Cdd:pfam01019   1 LDILRKGGNAVDAAVAAALCLGVVEPHSSGIGGGGFMLIYDAKTGKVLVIDARETAPAAATKDMFDG----KGDSKLSLT 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 146 GAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQRRLERAfaerqleeiENARRTYWPN 225
Cdd:pfam01019  77 GGLAVGVPGEVAGLAEAHKRYGRLPWADLLEPAIKLARDGFPVSPALARALARAEERLRAD---------PGLRKIFLPT 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 226 GVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWVDPLCVDYRaGVSLCELP 305
Cdd:pfam01019 148 GRVLKAGELLKQPALAKTLELIAEEGPDAFYRGELAQQLVADLQANGGIITAEDLANYRVKIREPLSADYG-GYTVYSPP 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 306 PNTQGVSALQMLQILRGYDMRAlGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLIAPGYADQRRAMIRMDRA 385
Cdd:pfam01019 227 PSSGGIALLQILNILEGFDLSS-LLNSAEYLHLLIEAMKLAYADRTRYLGDPDFVPVPVENLLSPEYAKERAKLINPNAA 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 386 MDTPDAGPDvlrrGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRG--------ELFALTDGHANIYAPR 457
Cdd:pfam01019 306 FPSSYAPED----GGTTHFSVVDRDGNAVSFTSTINLGFGSGVVVPGTGILLNNEMddfstppgNAFGLDPSPANAIAPG 381
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 458 KRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHgddaeptgeppQDKGKVFLET 537
Cdd:pfam01019 382 KRPLSSMAPTIVLDDGKPVLVVGAPGGSRIISAVLQVIVNVLDLGLDLQQAVDAPRIHH-----------QLPDVLEVEP 450
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 1786814647 538 GFTPAVREALRARGHDVRPGDGSFGGYQAIMRDAERGVYVAATEMRKDG 586
Cdd:pfam01019 451 GFPEEVLAELEARGHKVKVVEDSSSVGAIQIVRRTGGVLYAASDPRRDG 499
g_glut_trans TIGR00066
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
52-579 1.49e-106

gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]


Pssm-ID: 129176  Cd Length: 516  Bit Score: 330.19  E-value: 1.49e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  52 GAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGldleTLR 131
Cdd:TIGR00066   1 GMVASLHALASEIGEDILKEGGNAFDAAVAVGLALAVVEPFMTGLGGGGFMLISGKKTKDTTAIDFRERAPAK----ATR 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 132 RVAREKGGGYIPSFGAA---AVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIAFYWANNQrrlerafa 208
Cdd:TIGR00066  77 DMFLDKSGNPLPGKSLTgglAIGVPGTVAGLEAALKKYGTLPLKDLIEPAIKLARNGFPINEALADTLELYE-------- 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 209 ERQLEEIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHHGEWV 288
Cdd:TIGR00066 149 EVLLTTKEDSKDIFNPTGKPLKEGDTLVQKDLAKSLELIAENGPDAFYKGDIAESIIDTLQKNGGIMTKKDLAAYDVEIR 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 289 DPLCVDYRAGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKYFADPAFALADLNRLI 368
Cdd:TIGR00066 229 KPLSGDYRGYQVYTTPPPSSGGIHLLQALNILENFDLSQYGDGSAETYQLLAEAMKLSYADRSRYLGDPEFVDVPLEELL 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 369 APGYADQRRAMIRMDRAMDTPDAGPDVLR---RGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLGFMLQDRGELFA 445
Cdd:TIGR00066 309 DKRYAKELAQSIKINKVDPKSTIYPGAYQpneGSQTTHFSVVDRDGNAVSLTTTINLEFGSGVHAPDTGILLNNEMDDFS 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 446 LTDGHANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDVQAAGDAARWRHGDDAEptge 525
Cdd:TIGR00066 389 LKPGGANAVEPNKRPLSSMAPTIVLKDGKPDLVVGSPGGSRIITTVLQTIVRHIDYGMPLAEAVSEPRIHHQWLPD---- 464
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1786814647 526 ppqdkgKVFLETGFTPAVREALRARGHDVR-PGDGSFGGYQAIMRDAERGVYVAA 579
Cdd:TIGR00066 465 ------ELRLEKGFPDDVLQLLKDMGHKVTlKEVFPMGVVQAIRVDPEGWLYGVS 513
ggt PRK09615
gamma-glutamyltranspeptidase; Reviewed
46-591 7.38e-60

gamma-glutamyltranspeptidase; Reviewed


Pssm-ID: 181992  Cd Length: 581  Bit Score: 209.38  E-value: 7.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  46 PVIAPHGAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVwdpRTKklhgyngSGRSpQGL 125
Cdd:PRK09615   44 PVRAKQGMVASVDATATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLL---RTK-------NGNT-TAI 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 126 DLetlRRVAREKGGG--YIPSFGAA----------AVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIA 193
Cdd:PRK09615  113 DF---REMAPAKATRdmFLDDQGNPdskksltshlASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALA 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 194 FYWannqrrleRAFAERQLEEIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGG 273
Cdd:PRK09615  190 DDL--------KTYGSEVLPNHENSKAIFWKEGEPLKKGDKLVQANLAKSLEMIAENGPDAFYKGTIADQIAQEMQKNGG 261
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 274 WLRYEDFVAHHGEWVDPLCVDYRAGVSLCELPPNTQGVSALQMLQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKY 353
Cdd:PRK09615  262 LITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEY 341
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 354 FADPAFALADLNRLIAPGYADQRRAMIRMDRAMDTPDAGPDVL---RRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVP 430
Cdd:PRK09615  342 LGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLapyESNQTTHFSVVDKDGNAVAVTYTLNTTFGTGIVA 421
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 431 DGLGFMLQDRGELFA----------LTDGHANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVD 500
Cdd:PRK09615  422 GNSGILLNNQMDDFSakpgvpnvygLVGGDANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSID 501
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 501 YGLDVQAAGDAARWRHgddaeptgEPPQDKGKVflETGFTPAVREALRARGHDVRPGDgSFGGYQAIMRDAERGVYVAAT 580
Cdd:PRK09615  502 YGMNVAEATNAPRFHH--------QWLPDELRV--EKGFSPDTLKLLEAKGQKVALKE-AMGSTQSIMVGPDGELYGASD 570
                         570
                  ....*....|.
gi 1786814647 581 EMRKDGAADGY 591
Cdd:PRK09615  571 PRSVDDLTAGY 581
PLN02198 PLN02198
glutathione gamma-glutamylcysteinyltransferase
37-591 3.17e-35

glutathione gamma-glutamylcysteinyltransferase


Pssm-ID: 177849  Cd Length: 573  Bit Score: 140.21  E-value: 3.17e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  37 SGAPWATRSPVIAPHGAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFaIVWDPRTKKLHGYN 116
Cdd:PLN02198   19 NAAAQKRQQSIVASHGAVATDDGRCSVIGMNVLREGGNAIDASVAAALCLGVVSPASSGIGGGAF-TLIKLANGEEIAYD 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 117 GSGRSPQGLDLETLRRVAREKgggyipSFGAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIPQTIafyw 196
Cdd:PLN02198   98 SRETAPLSATENMYGGNVELK------KKGALSVGVPGEVAGLFTAWKQHGKLPWKRLVRPAEKLAAEGFKISKYL---- 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 197 annqrRLERAFAERQLEEIENARRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLR 276
Cdd:PLN02198  168 -----YMQMNATRSDILADKGLSDLFVSNGELKKPGTICHNPKLALTLRLIGEYGPKAFYNGTVGVNLVRDIQKSGGIIT 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 277 YEDFVAHHGEWVDPLCVDYRAGVSLCELPPNTQGVSALQMLQILRGYDMRAlGFQTADSLHVQIEAKRLVFADRAKyFAD 356
Cdd:PLN02198  243 LKDLQSYRVKVKEPLSADILGYRVLGMPPPSSGGAAMMLILNILAQYGIPS-GVSGPLGVHRLIEALKHAFAVRMN-LGD 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 357 PAFalADLNR----LIAPGYADQRRAMIRMDRAMDTPDAGP--DVLRRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVP 430
Cdd:PLN02198  321 PDF--VDVTKvvsdMLSPKFAQDLKSKINDNKTFDPKHYGGrwNQIDDHGTSHLSIIDSERNAVSMTSTINGYFGALMLS 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 431 DGLGFMLQDRGELFALTDGH-----------ANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIV 499
Cdd:PLN02198  399 PSTGIVLNNEMDDFSIPMKSggnldvpppapANFIRPGKRPLSSMTPTIVLKDGKVKAAVGASGGANIIAGTTEVYLNHF 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 500 DYGLDVQAAGDAARWRHgdDAEPTGEPPQDKGKVFLETGFTPA-VREALRARGHDVRPGDG----SFGGYQAIMRDAERG 574
Cdd:PLN02198  479 FLKMDPLSSVLAPRIYH--QLIPNRASYENWTTVYNDHFEIPKaTRVVLEKKGHVLSPIAGgtiaQFIVQESGENSGGRS 556
                         570
                  ....*....|....*..
gi 1786814647 575 VYVAATEMRKDGAADGY 591
Cdd:PLN02198  557 ELVAVSDPRKGGFPSGY 573
PLN02180 PLN02180
gamma-glutamyl transpeptidase 4
47-516 4.41e-30

gamma-glutamyl transpeptidase 4


Pssm-ID: 177836  Cd Length: 639  Bit Score: 125.18  E-value: 4.41e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647  47 VIAPHGAAATAHPLATQIAIDVLKDGGSAVDAAIAANAMLGLVEPTGNGMGGDVFAIVWDPRTKKLHGYNGSGRSPQGLD 126
Cdd:PLN02180   78 VESENGVVAADDARCSEIGASVLRRGGHAVDAAVAITLCIGVVNPMSSGIGGGSFLIVSSQKDSKAEAFDMRETAPLAAS 157
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 127 LETLRRVAREKgggyipSFGAAAVTVPGTVDGWYALHGRFGRLPMRRLLQPAIDYAENGAPIpqtiafywannQRRLERA 206
Cdd:PLN02180  158 KDMYKNDASAK------SLGALSMGVPGEIAGLYEAWKRYGRLPWKPLFEPAIELARDGFVV-----------HPYLGKA 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 207 FAERQLEEIENA--RRTYWPNGVTPAAGSLFHNPDLARTLRALQRGGRRAFYEGPVARATDAYMRRIGGWLRYEDFVAHH 284
Cdd:PLN02180  221 ISSHAAMILKDPglRSVFSRNGQVLKPGETCYNPELAQSLETISEQGPGAFYNGTIGEKLVKDVKKAGGIITMDDLRSYE 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 285 GEWVDPLCVDYrAGVSLCELPPNTQGVSALQM-LQILRGYDMRALGFQTADSLHVQIEAKRLVFADRAKyFADPAFA--L 361
Cdd:PLN02180  301 VLVTDAMSVDV-MGYTIHGMPPPSGGTLGFSMvIDILDSYSNLYTASGRELGLHRLIEAMKHMFAARMD-LGDPEFVniT 378
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 362 ADLNRLIAPGYADQRRamirmDRAMDTPDAGPDV-------LRRGDTTYFTTADANGMMVSIIQSNYRGMGSGLVPDGLG 434
Cdd:PLN02180  379 NAMNQMLSKAHAEEIQ-----KRIFDNTTFPPEYylnrwsqLRDQGTSHFCIVDADRNSVSMTSTVNYGFGAGVLSPSTG 453
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1786814647 435 FMLQDRGELFA---------LTDGHANIYAPRKRPFHTIIPAFALRNGEPWLAFGLMGGDVQPQGHVQIILNIVDYGLDV 505
Cdd:PLN02180  454 IVLNNEMDDFStpaeitpdmLPPAPTNFIEPNKRPLSSMTPLVITKDGEFVAALGGAGGMHIIPAVLQVFLNCFVLNMKP 533
                         490
                  ....*....|.
gi 1786814647 506 QAAGDAARWRH 516
Cdd:PLN02180  534 KEAVESARIYH 544
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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