|
Name |
Accession |
Description |
Interval |
E-value |
| NSP2-B_epitope |
pfam14757 |
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a ... |
804-1075 |
0e+00 |
|
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a non-essential part of the nsp2 (non-structural protein) subunit section of the arterivirus polyprotein. This domain carries seven small sequence-regions that are predicted to be potential B-cell epitopes.
:
Pssm-ID: 373272 Cd Length: 272 Bit Score: 564.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 804 VKNYPRWTPSPPPPRVQPRKTKPVKSLPGNKPVPAPRRKVRSDCGSPISMGDNVPDGREDLTVGGPLDLSTPSEPMTPLS 883
Cdd:pfam14757 1 VKNYPRWTPPPPPPRVQPRKTKSVKSLPENKPVPAPRRKVRSDCGSPVLMGDNVPNGWEDLTVGGPLDLPTPSEPMTPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 884 EPAPMPALQYISRPVTPLSVLAPVPAPRRTVSRPVTPLSEPIFVSAPRHKFQQVEEANLAATMLTHQDEPLDLSASSQTE 963
Cdd:pfam14757 81 EPVLVPALQHIPRPVTPLSGPAPVPAPRRTVSRPMTPLSEPIFVSAPRHKFQQVEEANLAATTLTCQDEPLDLSASSQTE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 964 YEASPLTPLQNMGILEVGGQEAEEVLSENSDTLNDINPAPVSSSSSLSSVKITRPKHSAQAIIDSGGPCSGHLRKGKEAC 1043
Cdd:pfam14757 161 YEASPLAPLQNMGILEAGGQEAEEVLSEISDILNDINPAPVSSSSSLSSVKITRPKYSAQAIIDSGGPCSGHLQKEKEAC 240
|
250 260 270
....*....|....*....|....*....|..
gi 1785995639 1044 LSIMREACDAAKLSDPATQEWLSRMWDRVDML 1075
Cdd:pfam14757 241 LSIMREACDATKLSDPATQEWLSRMWDRVDML 272
|
|
| Peptidase_S32 |
pfam05579 |
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing ... |
1717-2014 |
1.68e-160 |
|
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing nidovirus polyprotein.
:
Pssm-ID: 253263 Cd Length: 297 Bit Score: 497.38 E-value: 1.68e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1717 LTILWLVFFLMSVNMPSGILTVVLLVALWLLGRYTNVVGLVTPYDIHHYTNGPRGVAALATAPDGTYLAAVRRAALTGRT 1796
Cdd:pfam05579 1 LTMLWVQFFLVFVNFWAGVAALVVLISLWLLARYTNVAGLVTPYDIHLVTSSPRGAAALATAPEGTYLAAVRRAALTGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1797 VLFTPSQLGSLLEGAFRTRKPSLNTVNVVGSSMGSGGVFTIDGKIKCVTAAHVLTGNSARVSGVGFNQMLDFDVKGDFAI 1876
Cdd:pfam05579 81 CLFVPSNFGSVLEGLFRTRKPALNVVSVFGSSSGSGGVFTINGNVVVVTASHVLGGNKARVSGVGFNQMLTFKTNGDYAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1877 ADCPNWQGAAPKTQFCeDGWTGRAYWLTSSGVEPGVIGNGFAFCFTACGDSGSPVITEAGELVGVHTGSNKQGGGIVTRP 1956
Cdd:pfam05579 161 AVVAEWPGAAPKLKFA-QGYTGRAYWSTSTGVEPGLLGKGFAFCFTKCGDSGSPVITEDGNLVGVHTGSNKRGSGMVTTP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1957 SGQFCNVAPIKLSELSEFFAGPKVPLGDVKVGSHIIKDICEVPSDLCALLAAKPELEG 2014
Cdd:pfam05579 240 SGKTLGMAPVKLSELSKHFAGPGVPVPTVKLPKNIIVDVEAVPSDLAALLESLPNLEG 297
|
|
| Pdase_C33_assoc |
pfam14756 |
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the ... |
536-682 |
3.24e-96 |
|
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the arteriviral polyproteins such as porcine arterivirus PRRSV and equine arterivirus EAV are auto-cleaved into functional units. the function of this particular domain is not known.
:
Pssm-ID: 258893 Cd Length: 147 Bit Score: 306.95 E-value: 3.24e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 536 GPPDAVEVFGFDPACLDRLAEVMHLPSSVIPAALAEMSGDPNRPASPVTTVWTVSQFFARHRGGEHPDQVRLGKIISLCQ 615
Cdd:pfam14756 1 GSPDAVEVSGFDPACLDRLAGVMHLPSSAIPAALAELSGDSDRPVSPATTVWTVSQFYARHSGGEHPDQVCLGKIISLCQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1785995639 616 VVEECCCHQNKTNRATPEEVAARIDQYLHGATSLEECLIRLERVCPPSAADTFFDWNVVLPGVGAST 682
Cdd:pfam14756 81 VIEDCCCSQNKTNRVTPEEVAAKIDQYLRGAASLEECLARLEKARPPSVLDTSFDWDVVLPGVEAAN 147
|
|
| Peptidase_C32 |
pfam05411 |
Equine arteritis virus putative proteinase; These proteins are characterized by a region that ... |
257-382 |
5.73e-72 |
|
Equine arteritis virus putative proteinase; These proteins are characterized by a region that has been proposed to have peptidase activity involved in viral polyprotein processing in replication.
:
Pssm-ID: 398854 Cd Length: 127 Bit Score: 236.67 E-value: 5.73e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 257 HGCLPANTVPEGNCWWRLFDSLPLDVQNKEIRRANQFGYQTKHGVAGKYLQRRLQANGLRAVTDTDGPIVVQYFSVRESW 336
Cdd:pfam05411 2 HGCLPADTVPEGKCWLKLFDHLPWEVQCKEIRLADQFGYQTKHGVQGKYLQRRLQVNGLRAVVDQNGPIIVQAFSVPESW 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1785995639 337 IRHFRLAEEPSLPGFEDLLRIRVEPNTSPLSDKGGKIFRFGSHKWY 382
Cdd:pfam05411 82 IRHLKLADEPVPPGFVDLLRFRVVPNTEPLAKTPEKIFRFGSHKWY 127
|
|
| Peptidase_C31 super family |
cl05133 |
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These ... |
57-161 |
5.38e-67 |
|
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These peptidases are involved in viral polyprotein processing in replication.
The actual alignment was detected with superfamily member pfam05410:
Pssm-ID: 461643 Cd Length: 105 Bit Score: 221.33 E-value: 5.38e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 57 LRWTLPRAFPTVECSPAGACWLSAIFPIARMTSGNLNFQQRMVRVAAEIYRAGQLTPAVLKALQVYERGCRWYPIVGPVP 136
Cdd:pfam05410 1 LTWEAPITYPTVECRPGGLCWLSAIFPIARMTSGNHNFQQRLVFVASVVYRDGKLTPKHLEELQVYERGCRWYPITGPVP 80
|
90 100
....*....|....*....|....*
gi 1785995639 137 GVAVFANSLHVSDKPFPGATHVLTN 161
Cdd:pfam05410 81 GIALYANSVHVSDEPFPGATHVLTN 105
|
|
| Arteri_nsp7a |
pfam16749 |
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a ... |
2201-2328 |
1.99e-65 |
|
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a role in viral RNA synthesis.
:
Pssm-ID: 374774 Cd Length: 128 Bit Score: 218.04 E-value: 1.99e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 2201 LTGALAMRLNDEDLDFLTKWTDFKCFVSASNMRNAAGQFIEAAYAKALRIELAQLVQVDKVRGTLAKLEAFADTVAPQLS 2280
Cdd:pfam16749 1 LTAALACALSDDDLDFLSQLVDCKAFVSASNMRNALGDFIESAYAKALRASLASVVAVAKSRRALAKLEDFADTVSPQLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1785995639 2281 PGDIVVALGHTPVGGIFDLKVGSTKHTLQAIETRVLAGSKMTVARVVD 2328
Cdd:pfam16749 81 PGDPVVLLGKTPVGEIFDIYVGDTKHVLRPIETRVVAGSKCTICTVVV 128
|
|
| Peptidase_C33 super family |
cl05135 |
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These ... |
428-535 |
6.67e-59 |
|
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These peptidases are involved in viral polyprotein processing in replication.
The actual alignment was detected with superfamily member pfam05412:
Pssm-ID: 114153 Cd Length: 108 Bit Score: 198.60 E-value: 6.67e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 428 HYSPPADGNCGWHCISAIANRMVNSKFETTLPERVRPSDDWATDEDLVNTIQILKLPAALDRNGACVGAKYVLKLEGEHW 507
Cdd:pfam05412 1 GYSPPGDGACGWHCISAIANRMFNDKFTTTLTECSRPSDDWASDQDLVQAIQTLRLPATLDRNGACPSAKYKLKLVGQHW 80
|
90 100
....*....|....*....|....*...
gi 1785995639 508 TVSVTLGMSPSLLPLECVQGCCEHKSGL 535
Cdd:pfam05412 81 TVTVRKGMAPGLLSPECVRGVCGHEGGL 108
|
|
| av_Nsp3_ER-remodelling |
cd22528 |
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This ... |
1600-1657 |
1.27e-21 |
|
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This domain is present in subunit Nsp3 of RNA-arteriviruses, such as porcine arterivirus PRRSV and equine arterivirus EAV. Nsp3 proteins are localized to the ER and appear to be essential for formation of double-membrane vesicles that originate from the ER during the life-cycle of the virus. Arterivirus Nsp3 is a predicted tetra-spanning transmembrane protein containing four transmembrane helices, with the N- and C-termini of the protein residing in the cytoplasm. It contains a cluster of four highly conserved cysteine residues that are predicted to reside in the first luminal domain of the protein. These conserved cysteines play a key role in the formation of double-membrane vesicles (DMVs); mutagenesis of each completely blocked DMV formation.
:
Pssm-ID: 412095 Cd Length: 57 Bit Score: 90.07 E-value: 1.27e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1600 GVYVTAVGSCGTGTNDPWCTNPFAVPGYGPGSLCTSRLCISQHGLTLPlTALVAGFGL 1657
Cdd:cd22528 1 GLYLQSPVSCGIGTNDPFCRNPFGVPVVGTQGVCHSGYCASAQGISLP-TSLLTQLSS 57
|
|
| ND5 super family |
cl33350 |
NADH dehydrogenase subunit 5; Provisional |
1241-1309 |
1.09e-03 |
|
NADH dehydrogenase subunit 5; Provisional
The actual alignment was detected with superfamily member MTH00063:
Pssm-ID: 214414 [Multi-domain] Cd Length: 522 Bit Score: 44.10 E-value: 1.09e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1241 VFFS-HLFKSDSGYSPGDWGFAAFTLFCLFLCYSYPFFGFVPLLGVFSGSSRRVRMGVFGCWLAFAVGLF 1309
Cdd:MTH00063 334 VFFSkHFLLSSFSSVVFNVSLLLVVILCVFLSYLYSFRLCLILFGVKSSLSSGVRFLFFNSGLMVFLWLF 403
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NSP2-B_epitope |
pfam14757 |
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a ... |
804-1075 |
0e+00 |
|
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a non-essential part of the nsp2 (non-structural protein) subunit section of the arterivirus polyprotein. This domain carries seven small sequence-regions that are predicted to be potential B-cell epitopes.
Pssm-ID: 373272 Cd Length: 272 Bit Score: 564.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 804 VKNYPRWTPSPPPPRVQPRKTKPVKSLPGNKPVPAPRRKVRSDCGSPISMGDNVPDGREDLTVGGPLDLSTPSEPMTPLS 883
Cdd:pfam14757 1 VKNYPRWTPPPPPPRVQPRKTKSVKSLPENKPVPAPRRKVRSDCGSPVLMGDNVPNGWEDLTVGGPLDLPTPSEPMTPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 884 EPAPMPALQYISRPVTPLSVLAPVPAPRRTVSRPVTPLSEPIFVSAPRHKFQQVEEANLAATMLTHQDEPLDLSASSQTE 963
Cdd:pfam14757 81 EPVLVPALQHIPRPVTPLSGPAPVPAPRRTVSRPMTPLSEPIFVSAPRHKFQQVEEANLAATTLTCQDEPLDLSASSQTE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 964 YEASPLTPLQNMGILEVGGQEAEEVLSENSDTLNDINPAPVSSSSSLSSVKITRPKHSAQAIIDSGGPCSGHLRKGKEAC 1043
Cdd:pfam14757 161 YEASPLAPLQNMGILEAGGQEAEEVLSEISDILNDINPAPVSSSSSLSSVKITRPKYSAQAIIDSGGPCSGHLQKEKEAC 240
|
250 260 270
....*....|....*....|....*....|..
gi 1785995639 1044 LSIMREACDAAKLSDPATQEWLSRMWDRVDML 1075
Cdd:pfam14757 241 LSIMREACDATKLSDPATQEWLSRMWDRVDML 272
|
|
| Peptidase_S32 |
pfam05579 |
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing ... |
1717-2014 |
1.68e-160 |
|
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing nidovirus polyprotein.
Pssm-ID: 253263 Cd Length: 297 Bit Score: 497.38 E-value: 1.68e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1717 LTILWLVFFLMSVNMPSGILTVVLLVALWLLGRYTNVVGLVTPYDIHHYTNGPRGVAALATAPDGTYLAAVRRAALTGRT 1796
Cdd:pfam05579 1 LTMLWVQFFLVFVNFWAGVAALVVLISLWLLARYTNVAGLVTPYDIHLVTSSPRGAAALATAPEGTYLAAVRRAALTGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1797 VLFTPSQLGSLLEGAFRTRKPSLNTVNVVGSSMGSGGVFTIDGKIKCVTAAHVLTGNSARVSGVGFNQMLDFDVKGDFAI 1876
Cdd:pfam05579 81 CLFVPSNFGSVLEGLFRTRKPALNVVSVFGSSSGSGGVFTINGNVVVVTASHVLGGNKARVSGVGFNQMLTFKTNGDYAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1877 ADCPNWQGAAPKTQFCeDGWTGRAYWLTSSGVEPGVIGNGFAFCFTACGDSGSPVITEAGELVGVHTGSNKQGGGIVTRP 1956
Cdd:pfam05579 161 AVVAEWPGAAPKLKFA-QGYTGRAYWSTSTGVEPGLLGKGFAFCFTKCGDSGSPVITEDGNLVGVHTGSNKRGSGMVTTP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1957 SGQFCNVAPIKLSELSEFFAGPKVPLGDVKVGSHIIKDICEVPSDLCALLAAKPELEG 2014
Cdd:pfam05579 240 SGKTLGMAPVKLSELSKHFAGPGVPVPTVKLPKNIIVDVEAVPSDLAALLESLPNLEG 297
|
|
| Pdase_C33_assoc |
pfam14756 |
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the ... |
536-682 |
3.24e-96 |
|
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the arteriviral polyproteins such as porcine arterivirus PRRSV and equine arterivirus EAV are auto-cleaved into functional units. the function of this particular domain is not known.
Pssm-ID: 258893 Cd Length: 147 Bit Score: 306.95 E-value: 3.24e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 536 GPPDAVEVFGFDPACLDRLAEVMHLPSSVIPAALAEMSGDPNRPASPVTTVWTVSQFFARHRGGEHPDQVRLGKIISLCQ 615
Cdd:pfam14756 1 GSPDAVEVSGFDPACLDRLAGVMHLPSSAIPAALAELSGDSDRPVSPATTVWTVSQFYARHSGGEHPDQVCLGKIISLCQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1785995639 616 VVEECCCHQNKTNRATPEEVAARIDQYLHGATSLEECLIRLERVCPPSAADTFFDWNVVLPGVGAST 682
Cdd:pfam14756 81 VIEDCCCSQNKTNRVTPEEVAAKIDQYLRGAASLEECLARLEKARPPSVLDTSFDWDVVLPGVEAAN 147
|
|
| Peptidase_C32 |
pfam05411 |
Equine arteritis virus putative proteinase; These proteins are characterized by a region that ... |
257-382 |
5.73e-72 |
|
Equine arteritis virus putative proteinase; These proteins are characterized by a region that has been proposed to have peptidase activity involved in viral polyprotein processing in replication.
Pssm-ID: 398854 Cd Length: 127 Bit Score: 236.67 E-value: 5.73e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 257 HGCLPANTVPEGNCWWRLFDSLPLDVQNKEIRRANQFGYQTKHGVAGKYLQRRLQANGLRAVTDTDGPIVVQYFSVRESW 336
Cdd:pfam05411 2 HGCLPADTVPEGKCWLKLFDHLPWEVQCKEIRLADQFGYQTKHGVQGKYLQRRLQVNGLRAVVDQNGPIIVQAFSVPESW 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1785995639 337 IRHFRLAEEPSLPGFEDLLRIRVEPNTSPLSDKGGKIFRFGSHKWY 382
Cdd:pfam05411 82 IRHLKLADEPVPPGFVDLLRFRVVPNTEPLAKTPEKIFRFGSHKWY 127
|
|
| Peptidase_C31 |
pfam05410 |
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These ... |
57-161 |
5.38e-67 |
|
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These peptidases are involved in viral polyprotein processing in replication.
Pssm-ID: 461643 Cd Length: 105 Bit Score: 221.33 E-value: 5.38e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 57 LRWTLPRAFPTVECSPAGACWLSAIFPIARMTSGNLNFQQRMVRVAAEIYRAGQLTPAVLKALQVYERGCRWYPIVGPVP 136
Cdd:pfam05410 1 LTWEAPITYPTVECRPGGLCWLSAIFPIARMTSGNHNFQQRLVFVASVVYRDGKLTPKHLEELQVYERGCRWYPITGPVP 80
|
90 100
....*....|....*....|....*
gi 1785995639 137 GVAVFANSLHVSDKPFPGATHVLTN 161
Cdd:pfam05410 81 GIALYANSVHVSDEPFPGATHVLTN 105
|
|
| Arteri_nsp7a |
pfam16749 |
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a ... |
2201-2328 |
1.99e-65 |
|
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a role in viral RNA synthesis.
Pssm-ID: 374774 Cd Length: 128 Bit Score: 218.04 E-value: 1.99e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 2201 LTGALAMRLNDEDLDFLTKWTDFKCFVSASNMRNAAGQFIEAAYAKALRIELAQLVQVDKVRGTLAKLEAFADTVAPQLS 2280
Cdd:pfam16749 1 LTAALACALSDDDLDFLSQLVDCKAFVSASNMRNALGDFIESAYAKALRASLASVVAVAKSRRALAKLEDFADTVSPQLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1785995639 2281 PGDIVVALGHTPVGGIFDLKVGSTKHTLQAIETRVLAGSKMTVARVVD 2328
Cdd:pfam16749 81 PGDPVVLLGKTPVGEIFDIYVGDTKHVLRPIETRVVAGSKCTICTVVV 128
|
|
| Peptidase_C33 |
pfam05412 |
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These ... |
428-535 |
6.67e-59 |
|
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These peptidases are involved in viral polyprotein processing in replication.
Pssm-ID: 114153 Cd Length: 108 Bit Score: 198.60 E-value: 6.67e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 428 HYSPPADGNCGWHCISAIANRMVNSKFETTLPERVRPSDDWATDEDLVNTIQILKLPAALDRNGACVGAKYVLKLEGEHW 507
Cdd:pfam05412 1 GYSPPGDGACGWHCISAIANRMFNDKFTTTLTECSRPSDDWASDQDLVQAIQTLRLPATLDRNGACPSAKYKLKLVGQHW 80
|
90 100
....*....|....*....|....*...
gi 1785995639 508 TVSVTLGMSPSLLPLECVQGCCEHKSGL 535
Cdd:pfam05412 81 TVTVRKGMAPGLLSPECVRGVCGHEGGL 108
|
|
| av_Nsp3_ER-remodelling |
cd22528 |
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This ... |
1600-1657 |
1.27e-21 |
|
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This domain is present in subunit Nsp3 of RNA-arteriviruses, such as porcine arterivirus PRRSV and equine arterivirus EAV. Nsp3 proteins are localized to the ER and appear to be essential for formation of double-membrane vesicles that originate from the ER during the life-cycle of the virus. Arterivirus Nsp3 is a predicted tetra-spanning transmembrane protein containing four transmembrane helices, with the N- and C-termini of the protein residing in the cytoplasm. It contains a cluster of four highly conserved cysteine residues that are predicted to reside in the first luminal domain of the protein. These conserved cysteines play a key role in the formation of double-membrane vesicles (DMVs); mutagenesis of each completely blocked DMV formation.
Pssm-ID: 412095 Cd Length: 57 Bit Score: 90.07 E-value: 1.27e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1600 GVYVTAVGSCGTGTNDPWCTNPFAVPGYGPGSLCTSRLCISQHGLTLPlTALVAGFGL 1657
Cdd:cd22528 1 GLYLQSPVSCGIGTNDPFCRNPFGVPVVGTQGVCHSGYCASAQGISLP-TSLLTQLSS 57
|
|
| ND5 |
MTH00063 |
NADH dehydrogenase subunit 5; Provisional |
1241-1309 |
1.09e-03 |
|
NADH dehydrogenase subunit 5; Provisional
Pssm-ID: 214414 [Multi-domain] Cd Length: 522 Bit Score: 44.10 E-value: 1.09e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1241 VFFS-HLFKSDSGYSPGDWGFAAFTLFCLFLCYSYPFFGFVPLLGVFSGSSRRVRMGVFGCWLAFAVGLF 1309
Cdd:MTH00063 334 VFFSkHFLLSSFSSVVFNVSLLLVVILCVFLSYLYSFRLCLILFGVKSSLSSGVRFLFFNSGLMVFLWLF 403
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
818-971 |
6.32e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 818 RVQPRKTKP-VKSL--------PGNKPVPAPRRKVRsdcGSPISMGDNVPDGREDLTVGGPLDLSTPSEPMTPLSePAPM 888
Cdd:PHA03247 2682 RPRRRAARPtVGSLtsladpppPPPTPEPAPHALVS---ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-PARP 2757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 889 PALQYISRPVTPLSVLAPVPAPRRTVSRP-VTPLSEPI-FVSAPRHKFQQVEEANLAATMLTHQDEPLDLSASSQTEYEA 966
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPaVASLSESReSLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
....*
gi 1785995639 967 SPLTP 971
Cdd:PHA03247 2838 APPPP 2842
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NSP2-B_epitope |
pfam14757 |
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a ... |
804-1075 |
0e+00 |
|
Immunogenic region of nsp2 protein of arterivirus polyprotein; This domain is in a non-essential part of the nsp2 (non-structural protein) subunit section of the arterivirus polyprotein. This domain carries seven small sequence-regions that are predicted to be potential B-cell epitopes.
Pssm-ID: 373272 Cd Length: 272 Bit Score: 564.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 804 VKNYPRWTPSPPPPRVQPRKTKPVKSLPGNKPVPAPRRKVRSDCGSPISMGDNVPDGREDLTVGGPLDLSTPSEPMTPLS 883
Cdd:pfam14757 1 VKNYPRWTPPPPPPRVQPRKTKSVKSLPENKPVPAPRRKVRSDCGSPVLMGDNVPNGWEDLTVGGPLDLPTPSEPMTPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 884 EPAPMPALQYISRPVTPLSVLAPVPAPRRTVSRPVTPLSEPIFVSAPRHKFQQVEEANLAATMLTHQDEPLDLSASSQTE 963
Cdd:pfam14757 81 EPVLVPALQHIPRPVTPLSGPAPVPAPRRTVSRPMTPLSEPIFVSAPRHKFQQVEEANLAATTLTCQDEPLDLSASSQTE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 964 YEASPLTPLQNMGILEVGGQEAEEVLSENSDTLNDINPAPVSSSSSLSSVKITRPKHSAQAIIDSGGPCSGHLRKGKEAC 1043
Cdd:pfam14757 161 YEASPLAPLQNMGILEAGGQEAEEVLSEISDILNDINPAPVSSSSSLSSVKITRPKYSAQAIIDSGGPCSGHLQKEKEAC 240
|
250 260 270
....*....|....*....|....*....|..
gi 1785995639 1044 LSIMREACDAAKLSDPATQEWLSRMWDRVDML 1075
Cdd:pfam14757 241 LSIMREACDATKLSDPATQEWLSRMWDRVDML 272
|
|
| Peptidase_S32 |
pfam05579 |
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing ... |
1717-2014 |
1.68e-160 |
|
Equine arteritis virus serine endopeptidase S32; Serine peptidases involved in processing nidovirus polyprotein.
Pssm-ID: 253263 Cd Length: 297 Bit Score: 497.38 E-value: 1.68e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1717 LTILWLVFFLMSVNMPSGILTVVLLVALWLLGRYTNVVGLVTPYDIHHYTNGPRGVAALATAPDGTYLAAVRRAALTGRT 1796
Cdd:pfam05579 1 LTMLWVQFFLVFVNFWAGVAALVVLISLWLLARYTNVAGLVTPYDIHLVTSSPRGAAALATAPEGTYLAAVRRAALTGRT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1797 VLFTPSQLGSLLEGAFRTRKPSLNTVNVVGSSMGSGGVFTIDGKIKCVTAAHVLTGNSARVSGVGFNQMLDFDVKGDFAI 1876
Cdd:pfam05579 81 CLFVPSNFGSVLEGLFRTRKPALNVVSVFGSSSGSGGVFTINGNVVVVTASHVLGGNKARVSGVGFNQMLTFKTNGDYAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1877 ADCPNWQGAAPKTQFCeDGWTGRAYWLTSSGVEPGVIGNGFAFCFTACGDSGSPVITEAGELVGVHTGSNKQGGGIVTRP 1956
Cdd:pfam05579 161 AVVAEWPGAAPKLKFA-QGYTGRAYWSTSTGVEPGLLGKGFAFCFTKCGDSGSPVITEDGNLVGVHTGSNKRGSGMVTTP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1957 SGQFCNVAPIKLSELSEFFAGPKVPLGDVKVGSHIIKDICEVPSDLCALLAAKPELEG 2014
Cdd:pfam05579 240 SGKTLGMAPVKLSELSKHFAGPGVPVPTVKLPKNIIVDVEAVPSDLAALLESLPNLEG 297
|
|
| Pdase_C33_assoc |
pfam14756 |
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the ... |
536-682 |
3.24e-96 |
|
Peptidase_C33-associated domain; The nsps or non-structural protein subunits of the arteriviral polyproteins such as porcine arterivirus PRRSV and equine arterivirus EAV are auto-cleaved into functional units. the function of this particular domain is not known.
Pssm-ID: 258893 Cd Length: 147 Bit Score: 306.95 E-value: 3.24e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 536 GPPDAVEVFGFDPACLDRLAEVMHLPSSVIPAALAEMSGDPNRPASPVTTVWTVSQFFARHRGGEHPDQVRLGKIISLCQ 615
Cdd:pfam14756 1 GSPDAVEVSGFDPACLDRLAGVMHLPSSAIPAALAELSGDSDRPVSPATTVWTVSQFYARHSGGEHPDQVCLGKIISLCQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1785995639 616 VVEECCCHQNKTNRATPEEVAARIDQYLHGATSLEECLIRLERVCPPSAADTFFDWNVVLPGVGAST 682
Cdd:pfam14756 81 VIEDCCCSQNKTNRVTPEEVAAKIDQYLRGAASLEECLARLEKARPPSVLDTSFDWDVVLPGVEAAN 147
|
|
| Peptidase_C32 |
pfam05411 |
Equine arteritis virus putative proteinase; These proteins are characterized by a region that ... |
257-382 |
5.73e-72 |
|
Equine arteritis virus putative proteinase; These proteins are characterized by a region that has been proposed to have peptidase activity involved in viral polyprotein processing in replication.
Pssm-ID: 398854 Cd Length: 127 Bit Score: 236.67 E-value: 5.73e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 257 HGCLPANTVPEGNCWWRLFDSLPLDVQNKEIRRANQFGYQTKHGVAGKYLQRRLQANGLRAVTDTDGPIVVQYFSVRESW 336
Cdd:pfam05411 2 HGCLPADTVPEGKCWLKLFDHLPWEVQCKEIRLADQFGYQTKHGVQGKYLQRRLQVNGLRAVVDQNGPIIVQAFSVPESW 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1785995639 337 IRHFRLAEEPSLPGFEDLLRIRVEPNTSPLSDKGGKIFRFGSHKWY 382
Cdd:pfam05411 82 IRHLKLADEPVPPGFVDLLRFRVVPNTEPLAKTPEKIFRFGSHKWY 127
|
|
| Peptidase_C31 |
pfam05410 |
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These ... |
57-161 |
5.38e-67 |
|
Porcine arterivirus-type cysteine proteinase alpha; Corresponds to Merops family C31. These peptidases are involved in viral polyprotein processing in replication.
Pssm-ID: 461643 Cd Length: 105 Bit Score: 221.33 E-value: 5.38e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 57 LRWTLPRAFPTVECSPAGACWLSAIFPIARMTSGNLNFQQRMVRVAAEIYRAGQLTPAVLKALQVYERGCRWYPIVGPVP 136
Cdd:pfam05410 1 LTWEAPITYPTVECRPGGLCWLSAIFPIARMTSGNHNFQQRLVFVASVVYRDGKLTPKHLEELQVYERGCRWYPITGPVP 80
|
90 100
....*....|....*....|....*
gi 1785995639 137 GVAVFANSLHVSDKPFPGATHVLTN 161
Cdd:pfam05410 81 GIALYANSVHVSDEPFPGATHVLTN 105
|
|
| Arteri_nsp7a |
pfam16749 |
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a ... |
2201-2328 |
1.99e-65 |
|
Arterivirus nonstructural protein 7 alpha; Nonstructural protein 7 alpha is likely to have a role in viral RNA synthesis.
Pssm-ID: 374774 Cd Length: 128 Bit Score: 218.04 E-value: 1.99e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 2201 LTGALAMRLNDEDLDFLTKWTDFKCFVSASNMRNAAGQFIEAAYAKALRIELAQLVQVDKVRGTLAKLEAFADTVAPQLS 2280
Cdd:pfam16749 1 LTAALACALSDDDLDFLSQLVDCKAFVSASNMRNALGDFIESAYAKALRASLASVVAVAKSRRALAKLEDFADTVSPQLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1785995639 2281 PGDIVVALGHTPVGGIFDLKVGSTKHTLQAIETRVLAGSKMTVARVVD 2328
Cdd:pfam16749 81 PGDPVVLLGKTPVGEIFDIYVGDTKHVLRPIETRVVAGSKCTICTVVV 128
|
|
| Peptidase_C33 |
pfam05412 |
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These ... |
428-535 |
6.67e-59 |
|
Equine arterivirus Nsp2-type cysteine proteinase; Corresponds to Merops family C33. These peptidases are involved in viral polyprotein processing in replication.
Pssm-ID: 114153 Cd Length: 108 Bit Score: 198.60 E-value: 6.67e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 428 HYSPPADGNCGWHCISAIANRMVNSKFETTLPERVRPSDDWATDEDLVNTIQILKLPAALDRNGACVGAKYVLKLEGEHW 507
Cdd:pfam05412 1 GYSPPGDGACGWHCISAIANRMFNDKFTTTLTECSRPSDDWASDQDLVQAIQTLRLPATLDRNGACPSAKYKLKLVGQHW 80
|
90 100
....*....|....*....|....*...
gi 1785995639 508 TVSVTLGMSPSLLPLECVQGCCEHKSGL 535
Cdd:pfam05412 81 TVTVRKGMAPGLLSPECVRGVCGHEGGL 108
|
|
| av_Nsp3_ER-remodelling |
cd22528 |
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This ... |
1600-1657 |
1.27e-21 |
|
intracellular membrane remodeller motif of arterivirus non-structural protein 3 (Nsp3); This domain is present in subunit Nsp3 of RNA-arteriviruses, such as porcine arterivirus PRRSV and equine arterivirus EAV. Nsp3 proteins are localized to the ER and appear to be essential for formation of double-membrane vesicles that originate from the ER during the life-cycle of the virus. Arterivirus Nsp3 is a predicted tetra-spanning transmembrane protein containing four transmembrane helices, with the N- and C-termini of the protein residing in the cytoplasm. It contains a cluster of four highly conserved cysteine residues that are predicted to reside in the first luminal domain of the protein. These conserved cysteines play a key role in the formation of double-membrane vesicles (DMVs); mutagenesis of each completely blocked DMV formation.
Pssm-ID: 412095 Cd Length: 57 Bit Score: 90.07 E-value: 1.27e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1785995639 1600 GVYVTAVGSCGTGTNDPWCTNPFAVPGYGPGSLCTSRLCISQHGLTLPlTALVAGFGL 1657
Cdd:cd22528 1 GLYLQSPVSCGIGTNDPFCRNPFGVPVVGTQGVCHSGYCASAQGISLP-TSLLTQLSS 57
|
|
| ND5 |
MTH00063 |
NADH dehydrogenase subunit 5; Provisional |
1241-1309 |
1.09e-03 |
|
NADH dehydrogenase subunit 5; Provisional
Pssm-ID: 214414 [Multi-domain] Cd Length: 522 Bit Score: 44.10 E-value: 1.09e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 1241 VFFS-HLFKSDSGYSPGDWGFAAFTLFCLFLCYSYPFFGFVPLLGVFSGSSRRVRMGVFGCWLAFAVGLF 1309
Cdd:MTH00063 334 VFFSkHFLLSSFSSVVFNVSLLLVVILCVFLSYLYSFRLCLILFGVKSSLSSGVRFLFFNSGLMVFLWLF 403
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
818-971 |
6.32e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 818 RVQPRKTKP-VKSL--------PGNKPVPAPRRKVRsdcGSPISMGDNVPDGREDLTVGGPLDLSTPSEPMTPLSePAPM 888
Cdd:PHA03247 2682 RPRRRAARPtVGSLtsladpppPPPTPEPAPHALVS---ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-PARP 2757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 889 PALQYISRPVTPLSVLAPVPAPRRTVSRP-VTPLSEPI-FVSAPRHKFQQVEEANLAATMLTHQDEPLDLSASSQTEYEA 966
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPaVASLSESReSLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
....*
gi 1785995639 967 SPLTP 971
Cdd:PHA03247 2838 APPPP 2842
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
819-930 |
8.80e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 41.58 E-value: 8.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1785995639 819 VQPRKTKPVKSLPGNKPVP---APRRKVRsdcgsPISMGDNVP----DGRedltvGGPLDLSTPSEPMTPLSEPAPMPAL 891
Cdd:PHA03379 448 VHDLEPGPLHDQHSMAPCPvaqLPPGPLQ-----DLEPGDQLPgvvqDGR-----PACAPVPAPAGPIVRPWEASLSQVP 517
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1785995639 892 QYISRPVTPLSV-LAPVPAPRRTVSRPVTPLSEPIFVSAP 930
Cdd:PHA03379 518 GVAFAPVMPQPMpVEPVPVPTVALERPVCPAPPLIAMQGP 557
|
|
| |
