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Conserved domains on  [gi|1782139323|gb|QGT83391|]
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ABC transporter permease subunit [Pseudomonas coronafaciens pv. coronafaciens]

Protein Classification

amino acid ABC transporter permease( domain architecture ID 11468467)

amino acid ABC transporter permease such as Rhizobium leguminosarum general L-amino acid transport system permease protein AapQ, which is part of a binding-protein-dependent transport system for L-amino acids and affects the uptake as well as efflux of these amino acids

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0006865
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 14-393 0e+00

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 637.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  14 LSDPKVRAWLFQIITVVAVISLGWFIFDNTQTNLQHRGITSGFGFLENSAGFGIAQHLIDYTESDTYARVFVIGLLNTLL 93
Cdd:COG4597    18 LYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYSPTDTYGRAFLVGLLNTLL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  94 VSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWYTAVFLTLPGPRQAHGYLDMFFVSSRGLNM 173
Cdd:COG4597    98 VAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSLFDGVFLNNRGLYL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 174 PRALPAEGAWAFLISLVVAVIAIVMMVRWANKRFEATGQPFHKFWVGLALLLVIPGLSMLIFGSPVHWELPQLKGFNFTG 253
Cdd:COG4597   178 PAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLSLDYPELKGFNFRG 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 254 GWVLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNS 333
Cdd:COG4597   258 GLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTSQYLNLTKNS 337

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 334 SLAAAIGYPEMVSLFAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIALIER 393
Cdd:COG4597   338 SLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
 
Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 14-393 0e+00

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 637.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  14 LSDPKVRAWLFQIITVVAVISLGWFIFDNTQTNLQHRGITSGFGFLENSAGFGIAQHLIDYTESDTYARVFVIGLLNTLL 93
Cdd:COG4597    18 LYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYSPTDTYGRAFLVGLLNTLL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  94 VSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWYTAVFLTLPGPRQAHGYLDMFFVSSRGLNM 173
Cdd:COG4597    98 VAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSLFDGVFLNNRGLYL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 174 PRALPAEGAWAFLISLVVAVIAIVMMVRWANKRFEATGQPFHKFWVGLALLLVIPGLSMLIFGSPVHWELPQLKGFNFTG 253
Cdd:COG4597   178 PAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLSLDYPELKGFNFRG 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 254 GWVLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNS 333
Cdd:COG4597   258 GLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTSQYLNLTKNS 337

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 334 SLAAAIGYPEMVSLFAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIALIER 393
Cdd:COG4597   338 SLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
PRK15100 PRK15100
cystine ABC transporter permease;
87-344 1.49e-19

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 86.34  E-value: 1.49e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  87 GLLNTLLVSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQIlfwytavfltlpgprqahgyldmffv 166
Cdd:PRK15100   18 GAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQL-------------------------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 167 ssrglnmpralpaegawaFLIslvvaviaivmmvrwankrfeatgqpfhkfwvglalllvipglsmlifgspvHWELPQL 246
Cdd:PRK15100   72 ------------------FMI----------------------------------------------------YYGLPQF 81

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 247 KgfnftggwVLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQF 326
Cdd:PRK15100   82 G--------IELDPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSF 153

                         250
                  ....*....|....*...
gi 1782139323 327 LNLAKNSSLAAAIGYPEM 344
Cdd:PRK15100  154 ISLVKDTSLAATIQVPEL 171
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 256-388 5.19e-15

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 73.35  E-value: 5.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 256 VLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSL 335
Cdd:TIGR03003  81 IRLPALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPV 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1782139323 336 AAAIGYPEMVSLfAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRI 388
Cdd:TIGR03003 161 LSAITVLELMNQ-AKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 181-377 6.26e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.36  E-value: 6.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 181 GAWAFLISLVVAVIAIVMMVRWANKrfeatgqPFHKFWVGLALLLVIPGLSMLIFGSPVHWELPQLKGFNFTGGWVLIpe 260
Cdd:cd06261     8 ALIATLLALVLGLLLGIILARKRGK-------LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALI-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 261 lisltlALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG 340
Cdd:cd06261    79 ------LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1782139323 341 YPEMVSLFAGTVLNQTGQAIEVIAITMSVYLAISISI 377
Cdd:cd06261   153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 262-388 2.84e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 50.38  E-value: 2.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 262 ISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG- 340
Cdd:pfam00528  53 LPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGs 132

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1782139323 341 YPEMVSLFAGTVLN-QTGQAIEVIAITMSVYLAISISISMLMNWYNKRI 388
Cdd:pfam00528 133 WPGLGLLLIEAILGyDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
 
Name Accession Description Interval E-value
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 14-393 0e+00

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 637.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  14 LSDPKVRAWLFQIITVVAVISLGWFIFDNTQTNLQHRGITSGFGFLENSAGFGIAQHLIDYTESDTYARVFVIGLLNTLL 93
Cdd:COG4597    18 LYDPRVRSILFQVLALALVVALVWYLVSNTLANLAARGIATGFGFLDRTAGFDISQSLIPYSPTDTYGRAFLVGLLNTLL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  94 VSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWYTAVFLTLPGPRQAHGYLDMFFVSSRGLNM 173
Cdd:COG4597    98 VAVLGIVLATILGFLVGIARLSSNWLVSKLATVYVEIFRNIPLLLQIFFWYFAVLEALPSPRQSLSLFDGVFLNNRGLYL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 174 PRALPAEGAWAFLISLVVAVIAIVMMVRWANKRFEATGQPFHKFWVGLALLLVIPGLSMLIFGSPVHWELPQLKGFNFTG 253
Cdd:COG4597   178 PAPVFEPGFGWVLAALLAAIVAAFVLRRWARRRQEATGQRFPVWWISLALLVGLPLLAFLLLGAPLSLDYPELKGFNFRG 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 254 GWVLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNS 333
Cdd:COG4597   258 GLTLSPEFVALLLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIPPLTSQYLNLTKNS 337

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 334 SLAAAIGYPEMVSLFAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIALIER 393
Cdd:COG4597   338 SLAVAIGYPDLVSVFAGTTLNQTGQAIEIIAITMAVYLTISLLISLLMNWYNRRVALVER 397
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 79-389 1.31e-52

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 174.49  E-value: 1.31e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  79 TYARVFVIGLLNTLLVSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWYtavfltlpgprqah 158
Cdd:COG0765    10 DYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIY-------------- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 159 gyldmFFVSSRGLNMPRalpaegawaflislvvaviaivmmvrwankrfeatgqpfhkFWVGLalllvipglsmlifgsp 238
Cdd:COG0765    76 -----FGLPLLGIDLSP-----------------------------------------FVAAV----------------- 92

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 239 vhwelpqlkgfnftggwvlipelisltLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVI 318
Cdd:COG0765    93 ---------------------------IALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRII 145

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1782139323 319 IPPLTSQFLNLAKNSSLAAAIGYPEMVSlFAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIA 389
Cdd:COG0765   146 LPPLGNEFISLLKDTSLVSVIGVPELTR-AAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRLA 215
PRK15100 PRK15100
cystine ABC transporter permease;
87-344 1.49e-19

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 86.34  E-value: 1.49e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  87 GLLNTLLVSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQIlfwytavfltlpgprqahgyldmffv 166
Cdd:PRK15100   18 GAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQL-------------------------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 167 ssrglnmpralpaegawaFLIslvvaviaivmmvrwankrfeatgqpfhkfwvglalllvipglsmlifgspvHWELPQL 246
Cdd:PRK15100   72 ------------------FMI----------------------------------------------------YYGLPQF 81

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 247 KgfnftggwVLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQF 326
Cdd:PRK15100   82 G--------IELDPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSF 153

                         250
                  ....*....|....*...
gi 1782139323 327 LNLAKNSSLAAAIGYPEM 344
Cdd:PRK15100  154 ISLVKDTSLAATIQVPEL 171
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
261-387 1.92e-17

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 80.64  E-value: 1.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 261 LISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG 340
Cdd:PRK15107   97 LISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLS 176

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1782139323 341 YPEMVSLfAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKR 387
Cdd:PRK15107  177 LADFFRT-ASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKR 222
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 87-391 1.33e-15

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 75.09  E-value: 1.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323  87 GLLNTLLVSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWYTAVFLTLPGPRqahgyldmffv 166
Cdd:PRK09494   18 GAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPMAFNDLR----------- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 167 ssrglnmpralpAEGAWAflislvvAVIAIVmmvrwankrfeatgqpfhkfwvglalllvipglsmlifgspvhwelpql 246
Cdd:PRK09494   87 ------------IDPFTA-------AVVTIM------------------------------------------------- 98

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 247 kgfnftggwvlipelisltlaltIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQF 326
Cdd:PRK09494   99 -----------------------INSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQW 155

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1782139323 327 LNLAKNSSLAAAIGYPEMV----SLFAGTVlnqtgQAIEVIAITMSVYLAISISISMLMNWYNKRIALI 391
Cdd:PRK09494  156 IISIKDTSLFIVIGVAELTrqgqEIIAGNF-----RALEIWSAVAVIYLIITLVLSFILRRLERRMKIL 219
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 256-388 5.19e-15

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 73.35  E-value: 5.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 256 VLIPELISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSL 335
Cdd:TIGR03003  81 IRLPALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFKETPV 160

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1782139323 336 AAAIGYPEMVSLfAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRI 388
Cdd:TIGR03003 161 LSAITVLELMNQ-AKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 87-144 1.70e-12

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 62.94  E-value: 1.70e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1782139323  87 GLLNTLLVSVIGIVLATLLGFIIGVARLSPNWMISKLATVYVEVFRNIPPLLQILFWY 144
Cdd:TIGR01726   8 GLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIY 65
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
184-393 6.38e-10

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 58.92  E-value: 6.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 184 AFLISLVVAVI-AIVMMVRWANKRFEATGqpfhkfWV----GLALLLVIpglsMLI-FGSPvhwelpQL-----KGFNFT 252
Cdd:PRK11123   21 ALIVGLALAMLfAVWESAKWRPVAWPGTA------LVtllrGLPEILVV----LFIyFGSS------QLlltlsDGFTLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 253 GGWVLIPELISLT-----------LALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPP 321
Cdd:PRK11123   85 LGFVQIPVQMDIEnfevspflcgvIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPG 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1782139323 322 LTSQFLNLAKNSSLAAAIGYPEMVsLFAGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIALIER 393
Cdd:PRK11123  165 LGNQWLVLLKDTALVSLISVNDLM-LQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRATRFER 235
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 181-377 6.26e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.36  E-value: 6.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 181 GAWAFLISLVVAVIAIVMMVRWANKrfeatgqPFHKFWVGLALLLVIPGLSMLIFGSPVHWELPQLKGFNFTGGWVLIpe 260
Cdd:cd06261     8 ALIATLLALVLGLLLGIILARKRGK-------LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALI-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 261 lisltlALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG 340
Cdd:cd06261    79 ------LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1782139323 341 YPEMVSLFAGTVLNQTGQAIEVIAITMSVYLAISISI 377
Cdd:cd06261   153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK15069 PRK15069
histidine ABC transporter permease HisM;
266-374 2.36e-08

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 54.29  E-value: 2.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 266 LALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIGYPEMV 345
Cdd:PRK15069  107 LAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFTATVPDIL 186

                          90       100
                  ....*....|....*....|....*....
gi 1782139323 346 SLfAGTVLNQTGQAIEVIAITMSVYLAIS 374
Cdd:PRK15069  187 KI-ARDINSATYQPFQAFGIAAVLYLIIS 214
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 262-388 2.84e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 50.38  E-value: 2.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 262 ISLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG- 340
Cdd:pfam00528  53 LPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGs 132

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1782139323 341 YPEMVSLFAGTVLN-QTGQAIEVIAITMSVYLAISISISMLMNWYNKRI 388
Cdd:pfam00528 133 WPGLGLLLIEAILGyDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 267-340 9.50e-07

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 49.28  E-value: 9.50e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1782139323 267 ALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG 340
Cdd:COG2011    98 PLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGAVG 171
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
185-320 1.59e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 46.69  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 185 FLISLVVAVIAIVM--MVRWANKRFEAtgqPFHKFWVGLALL-LVIPG-------LSMLIFGSPVHWELPQLKGFNFtgg 254
Cdd:COG1178    60 LLLALLVTLLSLLLgvPLAWLLARTDF---PGRRLLRWLLLLpLALPPyvvalawIALFGPNGLLNTLLRALFGLEP--- 133

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1782139323 255 wvliPELISLT---LALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIP 320
Cdd:COG1178   134 ----PDIYGLGgiiLVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAA 198
artM PRK11122
arginine ABC transporter permease ArtM;
266-393 1.01e-04

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 43.41  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 266 LALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRkVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIGYPEMV 345
Cdd:PRK11122   96 LALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVLVFKSTSLAYTITLMDVM 174

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1782139323 346 SLfaGTVLNQTGQAIEVIAITMSVYLAISISISMLMNWYNKRIALIER 393
Cdd:PRK11122  175 GY--SQLLYGRTYDVMVFGAAGIIYLVVNGLLTLLMRLIERKALAFER 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
268-340 1.08e-04

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 43.18  E-value: 1.08e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1782139323 268 LTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVIIPPLTSQFLNLAKNSSLAAAIG 340
Cdd:PRK10782   96 LTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVG 168
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 185-319 1.55e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 42.79  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 185 FLISLVVAVIAIVMMVrWANKRFEATGQPFHKFWVGLALL-LVIP----GLSMLIFgspvhwelpqLKGFNFTGGWVlip 259
Cdd:COG1177    67 LLIALLSTLLATVLGT-PAALALARYRFRGRRLLLALLLLpLVVPgivlGVALLLL----------FSALGLSGGLW--- 132

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 260 eliSLTLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVII 319
Cdd:COG1177   133 ---GLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGIL 189
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
185-319 9.68e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 41.30  E-value: 9.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1782139323 185 FLISLVVAVIAIV--MMVRWANKRfeaTGQPFHKFWVGLALL-LVIPG----LSMLIFgspvhweLPQLKGFNFTGGWVL 257
Cdd:COG1178   344 LLLALLAALLAVLlaLLLAYLVRR---RRGRLARLLDRLAMLpYAVPGivlgLGLLLL-------FNRPLPLLLYGTLAI 413

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1782139323 258 IPelisltLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVII 319
Cdd:COG1178   414 LV------LAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLL 469
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 265-319 3.36e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 38.96  E-value: 3.36e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1782139323 265 TLALTIYTAAFIAEIVRSGIKSVSHGQTEAARSLGLRPGPTLRKVIIPQALRVII 319
Cdd:COG0555   140 VLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALL 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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