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Conserved domains on  [gi|1781406432|dbj|GED95514|]
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glycine betaine/carnitine/choline ABC transporter substrate-binding and permease protein [Lentilactobacillus buchneri subsp. silagei]

Protein Classification

ABC transporter permease/substrate-binding protein( domain architecture ID 10787289)

ABC transporter permease/substrate-binding protein containing transmembrane (TM) and type 2 periplasmic-binding protein (PBP2) components of an ABC transporter involved in the transport of one or more from a variety of substrates including glycine betaine and choline

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PBP2_ChoS cd13610
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ...
236-501 1.86e-147

Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


:

Pssm-ID: 270328  Cd Length: 264  Bit Score: 422.77  E-value: 1.86e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKKVNSePQL 315
Cdd:cd13610     1 SIVIAGKLGSEPDILINMYKLLIEEETPDLQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSND-PME 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13610    80 VYEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KsVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13610   160 N-VKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITD 238
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13610   239 EEMQEMNYRVDVKHKSAAKVAKEYLQ 264
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-202 3.80e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.01  E-value: 3.80e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432   1 MIDEVVAYVDKNAAAIMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  81 GTVPAIIALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1781406432 161 GGGGLGTYILLGIQTNNNAALIVGAVLSAILALVASWLIKVL 202
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALL 202
 
Name Accession Description Interval E-value
PBP2_ChoS cd13610
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ...
236-501 1.86e-147

Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270328  Cd Length: 264  Bit Score: 422.77  E-value: 1.86e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKKVNSePQL 315
Cdd:cd13610     1 SIVIAGKLGSEPDILINMYKLLIEEETPDLQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSND-PME 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13610    80 VYEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KsVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13610   160 N-VKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITD 238
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13610   239 EEMQEMNYRVDVKHKSAAKVAKEYLQ 264
OsmF COG1732
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ...
208-503 4.26e-117

Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441338 [Multi-domain]  Cd Length: 294  Bit Score: 346.36  E-value: 4.26e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 208 KKLGIGVLVVLILGGAGLGWSLFNKPSQTITIAGKMGGEPEILINMYKDLVKQESLqtKVQLKPNFGGTSFLFKALQSDQ 287
Cdd:COG1732     3 RLLLLALALAAALALAGCGLASAAAAGDTIVVGSKNFTEQEILAEIYAQALEAAGL--KVERKLNLGGTEVVRQALKSGE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 288 IDVYPEFTGTVLQSLVHspKKVNSEPQLAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGS 367
Cdd:COG1732    81 IDLYPEYTGTALTTYLK--EDPITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 368 QLTGAFDPDFYQQSDGYPGLRKAYHFQLKSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQG 447
Cdd:COG1732   159 ELTLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNA 238
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1781406432 448 APLMTDQFAKTHPQVVRALSRLAGKITTRDMQEMNYQVTVKHRSAAAVAKQYLQQH 503
Cdd:COG1732   239 APLVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-202 3.80e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.01  E-value: 3.80e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432   1 MIDEVVAYVDKNAAAIMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  81 GTVPAIIALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1781406432 161 GGGGLGTYILLGIQTNNNAALIVGAVLSAILALVASWLIKVL 202
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALL 202
OpuAC pfam04069
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ...
236-502 7.90e-56

Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).


Pssm-ID: 397954 [Multi-domain]  Cd Length: 257  Bit Score: 187.15  E-value: 7.90e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQTKvqlKPNFGGTSFLFKALQSDQIDVYP-EFTGTvlqslvhspkkvnsepq 314
Cdd:pfam04069   2 TIVIGSKNWTEQEILANIAAQLLEALGYVVE---LVGLGSSAVLFAALASGDIDLYPeEWTGT----------------- 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 315 lAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYP------GLR 388
Cdd:pfam04069  62 -TYEAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWGcmrsteGLL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 389 KAYHFQL-----KSVRTMEPSLrYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPP-YQGAPLMTDQFAKTHPQV 462
Cdd:pfam04069 141 KAYGLDKyelveGSEAAMDALI-YAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEV 219
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1781406432 463 VRALSRLagKITTRDMQEMNYQVTVKHRSAAAVAKQYLQQ 502
Cdd:pfam04069 220 AAFLNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLAE 257
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
20-194 6.73e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.86  E-value: 6.73e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  20 LWQHIEISLIAILITIVIAIPLAIGLV-NRPKIGEIISQIAGVIQTIPSLAVLGILIPFVG---------IGTVPAIIAL 89
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILArKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  90 VLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALIGGGGLGTYI 169
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....*
gi 1781406432 170 LLGIQTNNNAALIVGAVLSAILALV 194
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALIL 185
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
28-143 5.29e-16

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 79.37  E-value: 5.29e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  28 LIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIMPIFQNTYAGLTH 107
Cdd:PRK10952  154 LTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQ 233
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1781406432 108 IDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGI 143
Cdd:PRK10952  234 VPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGV 269
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
37-204 1.67e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 71.56  E-value: 1.67e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  37 IAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPF-----VGIGTVPAIIALVLYAIMPIFQNTYAGLTHIDPV 111
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 112 LLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALIGGGGLGTYILLGIQ-----TNNNAALIVGAV 186
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIlgydyPEIQGPVLAAAL 161
                         170
                  ....*....|....*...
gi 1781406432 187 LSAILALVASWLIKVLSQ 204
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDP 179
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
16-149 5.55e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 53.70  E-value: 5.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAI----GLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVL 91
Cdd:TIGR01097  56 ILKALLETLAMAILGTVLAAVLAVPLALlaarNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAF 135
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1781406432  92 YAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILS--------GIRIATVL 149
Cdd:TIGR01097 136 HTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAVL 201
 
Name Accession Description Interval E-value
PBP2_ChoS cd13610
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ...
236-501 1.86e-147

Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270328  Cd Length: 264  Bit Score: 422.77  E-value: 1.86e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKKVNSePQL 315
Cdd:cd13610     1 SIVIAGKLGSEPDILINMYKLLIEEETPDLQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSND-PME 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13610    80 VYEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KsVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13610   160 N-VKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITD 238
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13610   239 EEMQEMNYRVDVKHKSAAKVAKEYLQ 264
OsmF COG1732
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ...
208-503 4.26e-117

Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441338 [Multi-domain]  Cd Length: 294  Bit Score: 346.36  E-value: 4.26e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 208 KKLGIGVLVVLILGGAGLGWSLFNKPSQTITIAGKMGGEPEILINMYKDLVKQESLqtKVQLKPNFGGTSFLFKALQSDQ 287
Cdd:COG1732     3 RLLLLALALAAALALAGCGLASAAAAGDTIVVGSKNFTEQEILAEIYAQALEAAGL--KVERKLNLGGTEVVRQALKSGE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 288 IDVYPEFTGTVLQSLVHspKKVNSEPQLAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGS 367
Cdd:COG1732    81 IDLYPEYTGTALTTYLK--EDPITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVAG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 368 QLTGAFDPDFYQQSDGYPGLRKAYHFQLKSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQG 447
Cdd:COG1732   159 ELTLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYNA 238
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1781406432 448 APLMTDQFAKTHPQVVRALSRLAGKITTRDMQEMNYQVTVKHRSAAAVAKQYLQQH 503
Cdd:COG1732   239 APLVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
PBP2_osmoprotectants cd13528
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 ...
236-501 6.45e-106

Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270246 [Multi-domain]  Cd Length: 264  Bit Score: 316.85  E-value: 6.45e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVkQESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKkVNSEPQL 315
Cdd:cd13528     1 TIVVGSKNFTEQYILGEMLAQLL-EANTDLTVERKLNLGGTEVAFNALKNGDIDLYVEYTGTALLTILKEDA-PITDPEE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13528    79 VYEKVKKEYEEKFGLTWLDPLGFNNTYALAVRKDTAEKYGLKTISDLAPHSDQLVFGADPEFYERSDGLPGLKKTYGFDF 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13528   159 KEVKTMDPGLTYEALDNGEVDVIDAFSTDGRIKAFDLVVLEDDKNFFPPYNAAPVVREDVLKKHPELEEVLNKLSGKLTD 238
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13528   239 ETMQQLNYQVDVEGKDPEEVARDFLK 264
PBP2_Opu_like_1 cd13609
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ...
236-501 7.46e-89

Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270327  Cd Length: 263  Bit Score: 272.94  E-value: 7.46e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESlQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKkvNSEPQL 315
Cdd:cd13609     1 TIVIGSKNFTEQLILGNMYADLIEANT-DIKVERKLNLGGSSVCFSALKNGDIDMYVDYTGTILVNILKEPP--ISDPDE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13609    78 VYNTVKELMKEKYNLEVLKPLGFNNTYTLAVRKETAEKYNLKTISDLAKVSDELTLGCTLEFLNREDGLPGLEKTYGLNF 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13609   158 KDVKGLDGSLRYTALENGEVDVIDAFSTDGLLKKFDLVVLEDDKNFFPPYYAVPLVREETLEKYPELEDVLNKLAGKISE 237
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13609   238 ETMRELNYKVDELGKDPEDVAHEFLV 263
PBP2_AfProX_like cd13607
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus ...
236-500 1.23e-78

Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus fulgidus and its related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus and its related proteins. AfProX is involved in uptake of compatible solutes such as the trimethylammonium compound glycine betaine and the dimethylammonium compound proline betaine, but the relative substrate preference is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. AfProX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270325  Cd Length: 261  Bit Score: 246.73  E-value: 1.23e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQtkVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKkvNSEPQL 315
Cdd:cd13607     1 TVVIGSKTFTEQYILAEMIAQLLEEAGYP--AEHREGLGGTRVLFEALKSGEIDVYVEYTGTLYAEILKRPE--TWDPAA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKfHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13607    77 VLAELKEALAER-GIVVAGPLGFENTYALAMREDRAEALGIRTISDLLARAPDLRFGFDPEFLDRPDGWPALRRVYGLPF 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITT 475
Cdd:cd13607   156 KEVRGLDHTLAYRALKSGQVDVIDAYTTDARIDAYDLRVLEDDRGAFPPYDAVLLYRADLAERAPKAVAALRRLEGRIDA 235
                         250       260
                  ....*....|....*....|....*
gi 1781406432 476 RDMQEMNYQVTVKHRSAAAVAKQYL 500
Cdd:cd13607   236 DTMRALNAQVDLEKRSEAEVAAEFL 260
PBP2_Opu_like_2 cd13613
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ...
236-501 6.57e-75

Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270331  Cd Length: 264  Bit Score: 237.24  E-value: 6.57e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILinmyKDLVKQE---SLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHspKKVNSE 312
Cdd:cd13613     1 RIIIGSKNFTEQVIL----GELLAQQieaRTDLKVERRFNLGGTFICHQALLSGAIDAYVEYTGTALTAILK--QPPIRD 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 313 PQLAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYH 392
Cdd:cd13613    75 PQRVYEQVKQLYADRFGLEVMPPLGFENTFAILVRGEDARKLGLKTLSDAAPYTPGWRAGFGYEFLERADGYPGLAKTYG 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 393 FQL-KSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAG 471
Cdd:cd13613   155 LKFaKTPRVMDLGLLYRALAQKQVDLIAGNSTDGLIAALDLVILEDDRHYFPPYQAVPVVRQATLAKYPELRTAIAELAG 234
                         250       260       270
                  ....*....|....*....|....*....|
gi 1781406432 472 KITTRDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13613   235 KISAETMQQMNYQVDGEHRDVAEVAREFLK 264
PBP2_ProWX cd13612
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ...
236-505 8.81e-73

Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270330  Cd Length: 267  Bit Score: 231.74  E-value: 8.81e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQEslqTKVQLKPNF---GGTSFLFKALQSDQIDVYPEFTGTVLQSLVhspKKVNSE 312
Cdd:cd13612     1 TIHIATKPMTEQYILGEMLKQLIEQD---TDLKVELTKgvgGGTSNIHPAMVKGEFDLYPEYTGTGWLFVL---KKDGTY 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 313 PQLAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYH 392
Cdd:cd13612    75 SEELFDQLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYG 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 393 FQLKSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGK 472
Cdd:cd13612   155 FNFKKTVDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGL 234
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1781406432 473 ITTRDMQEMNYQVTVKHRSAAAVAKQYLQQHHL 505
Cdd:cd13612   235 ISDEDMAEMNYQVEIEKKDPKDVAKEFLEEKGL 267
PBP2_OpuCC_like cd13608
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; ...
236-501 2.38e-72

Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270326  Cd Length: 265  Bit Score: 230.59  E-value: 2.38e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQEsLQTKVQLKPNFGGTSFLFKALQSDQIDV-YPEFTGTVLQS-LVHSPKKvnsEP 313
Cdd:cd13608     1 TIRIGSQSTTESQILAEMVKQLIEHY-TDLKVELINNLGSSTVQHQAMLNGDANIsAARYTGTDLTGeLGMEPIK---DP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 314 QLAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQ-QSDGYPGLRKAYH 392
Cdd:cd13608    77 EKALKVVQKEFQKRFDQTWFDSYGFANTYAFMVTKEFAEKYNLKKVSDLKKVADNLKLGVDTSWLNrKGDGYPGFKETYG 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 393 FQLKSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGK 472
Cdd:cd13608   157 FDFGTVYPMQIGLVYDAVASGKMDVVLGYSTDGRIKSYDLVVLEDDKQFFPPYDASPVATNEILKKYPELEEILEKLEGK 236
                         250       260
                  ....*....|....*....|....*....
gi 1781406432 473 ITTRDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13608   237 ISTETMQELNYQVDNDLKEPSVVAKEFLE 265
PBP2_QAT_like cd13614
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 ...
236-501 3.05e-71

Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative quaternary amine ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270332  Cd Length: 264  Bit Score: 227.65  E-value: 3.05e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLqtKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPkkVNSEPQL 315
Cdd:cd13614     1 AIRVGSKNFTEQFILGEMYALALEDAGI--KVERKLNLGGTLIAHQALVNGEIDLYPEYTGTALLTVLKGE--PSSDAKQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAY-HFQ 394
Cdd:cd13614    77 VYKTVKDAYAEQFQLTWLEPAPFNNTYALVMTRETAEKYGIKTLSDLAKAAGELVFGGGPEFQDREDGLPGLKAKYgAFD 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 395 LKSVRTMEPS-LRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKI 473
Cdd:cd13614   157 FKEFVQVDPLgLRYQALAQGQIDVAVGFGTDGQIAAYGLVVLEDDKNLFPPYQVAPVVRQDVLDANPKIAEVLNKLSALL 236
                         250       260
                  ....*....|....*....|....*...
gi 1781406432 474 TTRDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13614   237 DNETMQRLNYEVDGNKREPKDVAREFLK 264
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
1-202 3.80e-70

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 223.01  E-value: 3.80e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432   1 MIDEVVAYVDKNAAAIMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGI 80
Cdd:COG1174     1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  81 GTVPAIIALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALI 160
Cdd:COG1174    81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1781406432 161 GGGGLGTYILLGIQTNNNAALIVGAVLSAILALVASWLIKVL 202
Cdd:COG1174   161 GAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALL 202
PBP2_ProWY cd13615
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding ...
236-500 7.63e-66

Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWY of Streptococcus thermophilus is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWY belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270333  Cd Length: 262  Bit Score: 213.46  E-value: 7.63e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLqtKVQLKPNFGGtSFLFKALQSDQIDVYPEFTGTVLQSLVHSPkkVNSEPQL 315
Cdd:cd13615     1 AIRVGSKDFTENLIVAEIYALALEDAGY--KVKRKPNISS-SVVHQALTSGQIDLYPEYTGTGLLAVLKKE--AITDPQK 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAY-HFQ 394
Cdd:cd13615    76 VYATVKDGYAKKFNLVWLDYAPANDGQGLVIRTSVAKKYGIKTISDLQKNASQIRFASQGEFDQREDGLPGLEKVYgKFS 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 395 LKSVRTMEPSLRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKIT 474
Cdd:cd13615   156 FKSTKVYDNGLKYQVLANDKADITPAYTTEGQLDTSKFTLLKDDKHVWPPYNLAPVVRKDVLKANPKIASALNKVSAKLT 235
                         250       260
                  ....*....|....*....|....*.
gi 1781406432 475 TRDMQEMNYQVTVKHRSAAAVAKQYL 500
Cdd:cd13615   236 TKTLTQLNAKVDVDKQEYADVAKDFY 261
OpuAC pfam04069
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ...
236-502 7.90e-56

Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).


Pssm-ID: 397954 [Multi-domain]  Cd Length: 257  Bit Score: 187.15  E-value: 7.90e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVKQESLQTKvqlKPNFGGTSFLFKALQSDQIDVYP-EFTGTvlqslvhspkkvnsepq 314
Cdd:pfam04069   2 TIVIGSKNWTEQEILANIAAQLLEALGYVVE---LVGLGSSAVLFAALASGDIDLYPeEWTGT----------------- 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 315 lAYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYP------GLR 388
Cdd:pfam04069  62 -TYEAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWGcmrsteGLL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 389 KAYHFQL-----KSVRTMEPSLrYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPP-YQGAPLMTDQFAKTHPQV 462
Cdd:pfam04069 141 KAYGLDKyelveGSEAAMDALI-YAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEV 219
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1781406432 463 VRALSRLagKITTRDMQEMNYQVTVKHRSAAAVAKQYLQQ 502
Cdd:pfam04069 220 AAFLNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWLAE 257
PBP2_YehZ cd13611
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 ...
266-501 3.15e-53

Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270329  Cd Length: 267  Bit Score: 180.86  E-value: 3.15e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 266 KVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKKVNSePQLAYR-----DAKNALsqkfhmRYLKPMAYQN 340
Cdd:cd13611    29 DVTDKTNLGGSASARQALENGQVDVYWEYTGTAWITYLGHTEPILD-PQEQYEavkdlDAEKGL------VWLDPAPLNN 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 341 GYAITVRQSTAKKYHLRTIADLQRV---GSQLTGAFDPDFYQQSDGYPGLRKAYHFQL--KSVRTMEPSLRYVALADGRV 415
Cdd:cd13611   102 TYALAMREATAEELGITTLSDLALAklpPGDRTFCVDAEFASRPDGLPPLLEAYGFEFprANVRQMDTGLVYTATANGQC 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 416 DVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKTHPQVVRALSRLAGKITTRDMQEMNYQVTVKHRSAAAV 495
Cdd:cd13611   182 DFGEVFTTDGRIKALDLVVLEDDKGFFPAYNAAPVVRTEVLDAHPELAEILNPISAKLDNDTMQELNARVDVDGEDPADV 261

                  ....*.
gi 1781406432 496 AKQYLQ 501
Cdd:cd13611   262 ARDWLV 267
PBP2_ProX_like cd13606
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related ...
236-501 4.12e-51

Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270324  Cd Length: 260  Bit Score: 175.06  E-value: 4.12e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVkqESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLvhSPKKVNSEPQL 315
Cdd:cd13606     1 TVVVGSADFPESEILAEIYAQAL--EAAGVKVTRKLNIGSREVYLPALEDGSIDLVPEYTGNLLQYL--DKDATATDPEE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMryLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLTGAFDPDFYQQSDGYPGLRKAYHFQL 395
Cdd:cd13606    77 VYAALKAALPEGLEV--LDPSPAEDKDALVVTKETAEKYGLKSIADLAPVAGELTLGGPPEFKTRPYGLPGLKEVYGVTF 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 396 KSVRTMEPS--LRYVALADGRVDVTDAYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDqfAKTHPQVVRALSRLAGKI 473
Cdd:cd13606   155 KEFKPLDAGgpLTVKALKDGTVQVANIFTTDPAIADNGLVVLEDPKNLFPAQNVVPLVRK--AKLDDKAADALNAVSAKL 232
                         250       260
                  ....*....|....*....|....*...
gi 1781406432 474 TTRDMQEMNYQVTVKHRSAAAVAKQYLQ 501
Cdd:cd13606   233 TTEDLTELNKQVVGDKADPADVAKEWLK 260
PBP2_OsmF cd13616
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 ...
236-500 1.51e-39

Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein OsmF of an ABC transporter (YehZYXW) from Escherichia coli is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. OsmF belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270334  Cd Length: 274  Bit Score: 144.40  E-value: 1.51e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 236 TITIAGKMGGEPEILINMYKDLVkqESLQTKVQLKPNFGGTSFLFKALQSDQIDVYPEFTGTVLQSLVHSPKKVNSEPQL 315
Cdd:cd13616     1 PVVVGSKIDTEGALLGNMIVLAL--EAHGFPVEDKTGLGTTPVVRKALLSGEIDLYPEYTGNGAFFFPEADDPVWKDARK 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 AYRDAKNALSQKFHMRYLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRV---GSQLTGAFDPDFYQQSDGYPGLRKAYH 392
Cdd:cd13616    79 GYETVKELDAKNNGLVWLDPAPANNTWAIAVRRDLAEKNNLKTLADLAAYvneGGAFKLAASAEFVERPDALPAFEKAYG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 393 FQLksvrtmePSLRYVALADGRVDVTD--------------AYTTDPQIREYHLVVLKDSKQFFPPYQGAPLMTDQFAKT 458
Cdd:cd13616   159 FKL-------SKDQLVILSGGNTAQTEqaaaqgtsgvnaamAYGTDGAIAALGLVVLEDPKGAQPVYAPAPVVRQEVLEA 231
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1781406432 459 HPQVVRALSRLAGKITTRDMQEMNYQVTVKHRSAAAVAKQYL 500
Cdd:cd13616   232 YPEIAEILKPVFATLDLKTLQELNARIAVEGESAEDVARDYL 273
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
20-149 1.40e-24

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 102.53  E-value: 1.40e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  20 LWQHIEISL----IAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIM 95
Cdd:COG0600    59 LWEHLLASLlrvlLGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFF 138
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1781406432  96 PIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVL 149
Cdd:COG0600   139 PILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGL 192
ProW COG4176
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
28-153 9.43e-23

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443335  Cd Length: 275  Bit Score: 97.86  E-value: 9.43e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  28 LIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLgilIPFV---GIGTVPAIIALVLYAIMPIFQNTYAG 104
Cdd:COG4176   100 LVAVLIALLIGIPLGILAARSDRVSRIVRPVLDFMQTMPAFVYL---IPAVmlfGIGKVPGVIATVIFALPPAIRLTNLG 176
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1781406432 105 LTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLV---------IGT 153
Cdd:COG4176   177 IRQVPKELVEAADAFGATPWQLLFKVQLPLALPTIMAGVNQTIMLAlsmvviasmIGA 234
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
20-194 6.73e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.86  E-value: 6.73e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  20 LWQHIEISLIAILITIVIAIPLAIGLV-NRPKIGEIISQIAGVIQTIPSLAVLGILIPFVG---------IGTVPAIIAL 89
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILArKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  90 VLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALIGGGGLGTYI 169
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....*
gi 1781406432 170 LLGIQTNNNAALIVGAVLSAILALV 194
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALIL 185
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
28-143 5.29e-16

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 79.37  E-value: 5.29e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  28 LIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIMPIFQNTYAGLTH 107
Cdd:PRK10952  154 LTALLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQ 233
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1781406432 108 IDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGI 143
Cdd:PRK10952  234 VPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGV 269
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
37-204 1.67e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 71.56  E-value: 1.67e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  37 IAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPF-----VGIGTVPAIIALVLYAIMPIFQNTYAGLTHIDPV 111
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPSD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 112 LLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATLAALIGGGGLGTYILLGIQ-----TNNNAALIVGAV 186
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIlgydyPEIQGPVLAAAL 161
                         170
                  ....*....|....*...
gi 1781406432 187 LSAILALVASWLIKVLSQ 204
Cdd:pfam00528 162 ILLLLNLLVDILQRLLDP 179
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
14-153 8.81e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 70.58  E-value: 8.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  14 AAIMQALWQHIEISLIAILITIVIAIPLAIGLVNRP-KIGEIISQIAGVIQTIPSLAV-LGILIPFVGIGTVP---AIIA 88
Cdd:COG1178   334 PSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRgRLARLLDRLAMLPYAVPGIVLgLGLLLLFNRPLPLLlygTLAI 413
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1781406432  89 LVL-YAI--MPI-FQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGT 153
Cdd:COG1178   414 LVLaYVVrfLPFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKE 482
PRK10160 PRK10160
taurine ABC transporter permease TauC;
20-145 2.37e-12

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 67.50  E-value: 2.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  20 LWQHIEISL----IAILITIVIAIPLAIGLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIM 95
Cdd:PRK10160   76 LWQHLAASLtrivLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1781406432  96 PIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRI 145
Cdd:PRK10160  156 PVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRI 205
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
14-142 2.44e-12

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 67.06  E-value: 2.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  14 AAIMQALWQHIEISLIAILITIVIAIPLAIGLVN-RPKIGEIISQIAGVIQTIPSLAV-LGILIPFVGIGTVP----AII 87
Cdd:COG1177    57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARyRFRGRRLLLALLLLPLVVPGIVLgVALLLLFSALGLSGglwgLIL 136
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1781406432  88 ALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSG 142
Cdd:COG1177   137 AHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
16-161 2.29e-11

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 63.54  E-value: 2.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAIGLVN--------RPKIGEIISQIAGVIQTIPSLAVLGILIPF----VG--IG 81
Cdd:COG2011    12 LLQATGETLYMVGVSTLIAVLLGLPLGVLLVLtrpggllpNPVLYRVLGVIVNIFRSIPFIILLVALIPLtrliVGtsIG 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  82 TVPAIIALVLYAImPIF-----QNtyagLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIGTATL 156
Cdd:COG2011    92 TTAAIVPLTIAAI-PFFarlveNA----LREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAM 166

                  ....*
gi 1781406432 157 AALIG 161
Cdd:COG2011   167 AGAVG 171
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
20-146 3.50e-11

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 63.80  E-value: 3.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  20 LWQHIEISLIAILITIVI--AIPLAIGLVN-RPKIGE-IISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIM 95
Cdd:PRK11365   58 LWQHLAISSWRALIGFSIggSLGLILGLISgLSRWGErLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLF 137
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1781406432  96 PIFQNTYAGLTHIDPVLLEAADALGVTKrFKLFR-IELPLAMPMILSGIRIA 146
Cdd:PRK11365  138 PIYINTWHGIRNIDRGLVEMARSYGLSG-IPLFIhVILPGALPSIMVGVRFA 188
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
16-149 1.29e-10

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 61.64  E-value: 1.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAI----GLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVL 91
Cdd:COG3639    49 LLSALLETLAIALLGTLLGAVLALPLAFlaarNLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAI 128
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1781406432  92 YAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILS--------GIRIATVL 149
Cdd:COG3639   129 HTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLSytlyrfeiNIRAATVL 194
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
7-140 2.16e-10

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 60.47  E-value: 2.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432   7 AYVDKNAAAIMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIgeiISQIAG----VIQTIPSLAVLGIL---IPFVG 79
Cdd:COG0765     6 SVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPV---LRWLATayveFFRGTPLLVQLFFIyfgLPLLG 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1781406432  80 I---GTVPAIIALVLYA---IMPIFQntyAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMIL 140
Cdd:COG0765    83 IdlsPFVAAVIALTLNSaayLAEIVR---AGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIIL 146
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
18-153 1.81e-09

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 58.62  E-value: 1.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  18 QALWQHIEISLIAILITIVIAIPLAIGLVNRPK---------------IGEIISQIA--------GVIQTIpsLAVLGIL 74
Cdd:COG1176    67 KVLLRTLWIALLTTLICLLLGYPIAYFLARAPPrwrnlllllvilpfwTSFLVRTYAwivllgrnGLLNSL--LLALGLI 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  75 -IPFVGIGTVPA-IIALV----LYAIMPIfqntYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATV 148
Cdd:COG1176   145 dEPLRLLYTEFAvVIGLVyvylPFMVLPL----YAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFI 220

                  ....*
gi 1781406432 149 LVIGT 153
Cdd:COG1176   221 PALGA 225
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
16-149 5.55e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 53.70  E-value: 5.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAI----GLVNRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVL 91
Cdd:TIGR01097  56 ILKALLETLAMAILGTVLAAVLAVPLALlaarNITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAF 135
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1781406432  92 YAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILS--------GIRIATVL 149
Cdd:TIGR01097 136 HTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAVL 201
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
28-152 7.45e-07

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 51.70  E-value: 7.45e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  28 LIAILITIVIAIP---LAIGLVNrpkigeiISQIAGVIQTIpSLAVLGILIPFVGiGTVPAIIALVLYAIMPIFQNTYAG 104
Cdd:COG1178    91 LLRWLLLLPLALPpyvVALAWIA-------LFGPNGLLNTL-LRALFGLEPPDIY-GLGGIILVLVLFNYPYVYLLLRAA 161
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1781406432 105 LTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIG 152
Cdd:COG1178   162 LRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLA 209
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
18-153 7.54e-07

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 50.90  E-value: 7.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  18 QALWQHIEISLIAILITIVIAIPLAIgLVNRPKIGE-----------IISQIAGVI--QTI--PSLAVLGILIPFVGIGT 82
Cdd:COG1175    76 NALGNTLLFTVVSVPLQLVLGLLLAL-LLNRKLRGRgffrtlfflpwVISPVVVALiwKWLfnPDYGLLNALLGALGLEP 154
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  83 VP-------AIIALVLYAI-------MPIFqntYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILsgirIATV 148
Cdd:COG1175   155 INwlgdpslALPAVIIVTVwkgtgfnMLIF---LAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTIL----FVLV 227

                  ....*.
gi 1781406432 149 L-VIGT 153
Cdd:COG1175   228 LsTIGA 233
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
24-154 1.93e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  24 IEISLIAILITIVIAIplAIGLV---NRPKIGEIISQIAGVIQTIPSLAVLGILIPFVGIGTVPAIIALVLYAIMPIFQN 100
Cdd:COG1173    82 LLVGLLAVLIALVIGV--LLGLLagyFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARL 159
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1781406432 101 TYA---GLTHIDPVllEAADALGVTKRFKLFRIELPLAMPMILsgirIATVLVIGTA 154
Cdd:COG1173   160 VRAqvlSLREREYV--EAARALGASPLRIIFRHILPNVLPPLI----VQATLGIASA 210
PBP2_BCP_1 cd13642
Substrate-binding domain of osmoregulatory ABC-type glycine betaine/choline/L-proline ...
238-503 2.47e-06

Substrate-binding domain of osmoregulatory ABC-type glycine betaine/choline/L-proline transport system-like; the type 2 periplasmic-binding protein fold; This subfamily is part of a high affinity multicomponent binding-protein-dependent transport system specific to certain quaternary ammonium compounds for osmoregulation. The periplasmic substrate-binding domain, which is often fused to the permease component of the ATP-binding cassette transporter complex, is involved in uptake of osmoprotectants (also termed compatible solutes) such as glycine betaine, proline betaine, choline, and carnitine. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. This domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.


Pssm-ID: 270360 [Multi-domain]  Cd Length: 292  Bit Score: 49.31  E-value: 2.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 238 TIAGKMGGEPEilinmykdlvkqesLQTkvqlkpnfGGTSFLFKALQSD--QIDVYPEFTGTVLQSLVHSpkkvnsepql 315
Cdd:cd13642    22 VIEDRLGGEAE--------------LQE--------GNNPIIFAAMDKGdgSIDVHPDVWLPNQQALWDK---------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 316 aYRDAKNALSqkfhmryLKPMAYQNGYAITVRQSTAKKYHLRTIADLQRVGSQLtgaFDPD------FYqqsDGYPGLRK 389
Cdd:cd13642    70 -YVTGGGTVA-------LNPNPYEGTQGICVPAATADKYGIKSDLDLTAPEAAL---FDSDgdgkgeIW---IGAPGWAS 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 390 AYHFQLKS-----VRTMEP-----SLRYVALAD----GRVDVTDAYTTDPQIREYHLVVLKDskqffPPYQGAPLMTDQ- 454
Cdd:cd13642   136 TNIEQIKAksygyDETWELeemseAVFYAQLDAayarGEPIVFYCYTPHWVFALYDLVQLEE-----PAYDAAKWTTVLp 210
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1781406432 455 ------------------------FAKT----HPQVVRALSRLagKITTRDMQEMNYQVTVKHRSAAAVAKQYLQQH 503
Cdd:cd13642   211 tedpdwleksnaacawadasvhiaYSASleerAPEVAAFLSRI--RLTPEEVNAMSYAVDVDGKDPAAVAREWVAAN 285
TauA COG0715
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion ...
214-466 2.95e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion transport and metabolism];


Pssm-ID: 440479 [Multi-domain]  Cd Length: 297  Bit Score: 48.85  E-value: 2.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 214 VLVVLILGGAGLGWSLFNKPSQTITIAG-KMGGEPEILINMYKDLVKQESLqtKVQLKPnFGGTSFLFKALQSDQIDVyp 292
Cdd:COG0715     1 LAALAALALAACSAAAAAAEKVTLRLGWlPNTDHAPLYVAKEKGYFKKEGL--DVELVE-FAGGAAALEALAAGQADF-- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 293 eftGTVLQSLVHspkkvnsepqlayrdakNALSQKFHMRYLKPMAYQNGYAITVRqstaKKYHLRTIADL--QRVGsqlt 370
Cdd:COG0715    76 ---GVAGAPPAL-----------------AARAKGAPVKAVAALSQSGGNALVVR----KDSGIKSLADLkgKKVA---- 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432 371 gafdpdFYQQSDGYPGLR---KAYHFQLKSVR--TMEPSLRYVALADGRVDVTDAYTTDPQ--IREYHLVVLKDSKQFFP 443
Cdd:COG0715   128 ------VPGGSTSHYLLRallAKAGLDPKDVEivNLPPPDAVAALLAGQVDAAVVWEPFESqaEKKGGGRVLADSADLVP 201
                         250       260
                  ....*....|....*....|....
gi 1781406432 444 PYQGAPL-MTDQFAKTHPQVVRAL 466
Cdd:COG0715   202 GYPGDVLvASEDFLEENPEAVKAF 225
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
27-152 3.57e-06

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 48.39  E-value: 3.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  27 SLIAILITIVIAIPLAIG-------LVNRPKIGEIISQIAGVIQTIPS----LAVLGILIPFVGIGTVPAI---IALVLY 92
Cdd:TIGR00974  59 TLLLTLLAIVIAVPLGIGaaiylaeYANGSRFTKIIRFAVDILAGVPSivvgLFGYGFFVLTYLGGGFSLLagaLALALL 138
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  93 AIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIG 152
Cdd:TIGR00974 139 ILPVIIRTTEEALKAVPKDLREASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAG 198
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
16-152 7.23e-05

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 43.95  E-value: 7.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAIGL-VNRP-------KIGEIISQIAGVIQTIPSLAVLGILIPF----VG--IG 81
Cdd:PRK10782    9 LVRGVWETLAMTFVSGFFGFVIGLPVGVLLyVTRPgqiianaKLYRTLSALVNIFRSIPFIILLVWMIPFtrviVGtsIG 88
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1781406432  82 TVPAIIALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVIG 152
Cdd:PRK10782   89 LQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVG 159
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
16-146 4.71e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 42.04  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  16 IMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIG-EIISQI-----------AGVIQTI---------PSLAVLGIL 74
Cdd:COG0555    52 VLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGkRLVDALvdlpfalptavAGIALLLlfgpngwlgQLLAPLGIK 131
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1781406432  75 IPFvgigTVPAIIALVLYAIMPIFQNT-YAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIA 146
Cdd:COG0555   132 VAF----TPLGIVLAQTFVSLPFVVRTvQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALA 200
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
12-142 2.04e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 39.97  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  12 NAAAIMQALWQHIEISLIAILITIVIAIPLAIGLVN-RPKIGEIISQIAGVIQTIPSLaVLGI--LIPFVGIGTVPAIIA 88
Cdd:PRK09500   51 NNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRyRFRGKKFVSGMLFVVMMSPDI-VMAIslLVLFMLLGIQLGFWS 129
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1781406432  89 LVLYAI---MPIFQNT-YAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSG 142
Cdd:PRK09500  130 LLFAHItfcLPFVVVTvYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
15-151 2.36e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 40.43  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  15 AIMQALWQHIEISLIAILITIVIAIPLAIGLVNRPKIGEIISQIAGVI-----QTIPSLAVL------GILIPFVGIGTV 83
Cdd:TIGR03262  51 GLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLpllapSLLPAISLIylfgnqGLLKGLLGGFSI 130
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1781406432  84 PA----IIALVLYAIMPIFQNTYAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMILSGIRIATVLVI 151
Cdd:TIGR03262 131 YGfwgiVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVI 202
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
15-139 4.25e-03

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 39.30  E-value: 4.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1781406432  15 AIMQALWQHIEISLIAILITIVIAIPLAIgLVNrpkigEIISQ-IAGVIQTI---P---SLAVL-GILIPFVGI--GTVP 84
Cdd:COG4209    83 DFWRVLRNTLLISLLKLVFGFPLPIILAL-LLN-----ELRSKrFKKTVQTIsylPhflSWVVVaGIVYQFLSPdtGLVN 156
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1781406432  85 AIIAL----------------VLYAIMPIFQNT-------YAGLTHIDPVLLEAADALGVTKRFKLFRIELPLAMPMI 139
Cdd:COG4209   157 QLLRAlggepinfltepkyfrPIYVFSGIWKEAgwgsiiyLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTI 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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