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Conserved domains on  [gi|1778926668|ref|WP_155047004|]
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IS630 family transposase [Piscirickettsia salmonis]

Protein Classification

transposase( domain architecture ID 10595512)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
12-142 1.40e-46

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


:

Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 148.97  E-value: 1.40e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  12 IVYMDEAGMDDTERYAYGHSAKGKRCYAEKPGKKSIRINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQCLIPCLSPGE 91
Cdd:pfam13358   2 LVFLDESGFNLGTVRRYGWAPKGRRPRGLKPYGRGGRVNVIGALTYKGGLAFVTFEETVNAEDFIAFLEQLLKPYLQPKI 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1778926668  92 TVIMDNASFHKSKGVKEAIED--AGCHLLFLPPYSPDLNPIEHVWSPLKNRVR 142
Cdd:pfam13358  82 VLVLDNASYHKSKAVRELVEAeaDGLELHYLPPYSPELNPIEILWSVLKRELL 134
 
Name Accession Description Interval E-value
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
12-142 1.40e-46

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 148.97  E-value: 1.40e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  12 IVYMDEAGMDDTERYAYGHSAKGKRCYAEKPGKKSIRINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQCLIPCLSPGE 91
Cdd:pfam13358   2 LVFLDESGFNLGTVRRYGWAPKGRRPRGLKPYGRGGRVNVIGALTYKGGLAFVTFEETVNAEDFIAFLEQLLKPYLQPKI 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1778926668  92 TVIMDNASFHKSKGVKEAIED--AGCHLLFLPPYSPDLNPIEHVWSPLKNRVR 142
Cdd:pfam13358  82 VLVLDNASYHKSKAVRELVEAeaDGLELHYLPPYSPELNPIEILWSVLKRELL 134
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
48-164 2.62e-45

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 150.40  E-value: 2.62e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  48 RINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQCLIPCLSPGETVIMDNASFHKSKGVKEAIEDAGCHLLFLPPYSPDL 127
Cdd:COG3335   158 RTNLIGALNLDGGLAVMVFDGSINGEVFIAFLEQLLLPYLKPGIVVILDNASFHKSKAVREWLEEAGIELLFLPPYSPDL 237
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1778926668 128 NPIEHVWSPLKNRVRMK---LDQDEinLETALSQVMKSMS 164
Cdd:COG3335   238 NPIERLWSKLKALLRKNrafRSKDE--LKAAVRSFLDRIS 275
transpos_IS630 NF033545
IS630 family transposase;
2-162 2.71e-42

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 142.78  E-value: 2.71e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668   2 EKVEKIDNDKIVYMDEAGMDDTERYAYGHSAKGKRCYAEKPGKKSIRINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQ 81
Cdd:NF033545  136 LYRAPPDPAEVVFIDESGIQLLDTRGRGWAPKGQRRPRVHVYGRRGTLNLFGALDPLTGKVFVLFTGRINSEDFIEFLEE 215
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  82 CLIPCLSPGETVIMDNASFHKSKGVKEAIEDAG-CHLLFLPPYSPDLNPIEHVWSPLKNRVRMKL---DQDEinLETALS 157
Cdd:NF033545  216 LLAAYPGKKIHLILDNASTHKSKKVREWLEEHGrIELHYLPPYSPWLNPIERVWAVLKRRLLRNRafrSVDE--LREAID 293

                  ....*
gi 1778926668 158 QVMKS 162
Cdd:NF033545  294 AFLNR 298
 
Name Accession Description Interval E-value
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
12-142 1.40e-46

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 148.97  E-value: 1.40e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  12 IVYMDEAGMDDTERYAYGHSAKGKRCYAEKPGKKSIRINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQCLIPCLSPGE 91
Cdd:pfam13358   2 LVFLDESGFNLGTVRRYGWAPKGRRPRGLKPYGRGGRVNVIGALTYKGGLAFVTFEETVNAEDFIAFLEQLLKPYLQPKI 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1778926668  92 TVIMDNASFHKSKGVKEAIED--AGCHLLFLPPYSPDLNPIEHVWSPLKNRVR 142
Cdd:pfam13358  82 VLVLDNASYHKSKAVRELVEAeaDGLELHYLPPYSPELNPIEILWSVLKRELL 134
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
48-164 2.62e-45

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 150.40  E-value: 2.62e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  48 RINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQCLIPCLSPGETVIMDNASFHKSKGVKEAIEDAGCHLLFLPPYSPDL 127
Cdd:COG3335   158 RTNLIGALNLDGGLAVMVFDGSINGEVFIAFLEQLLLPYLKPGIVVILDNASFHKSKAVREWLEEAGIELLFLPPYSPDL 237
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1778926668 128 NPIEHVWSPLKNRVRMK---LDQDEinLETALSQVMKSMS 164
Cdd:COG3335   238 NPIERLWSKLKALLRKNrafRSKDE--LKAAVRSFLDRIS 275
transpos_IS630 NF033545
IS630 family transposase;
2-162 2.71e-42

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 142.78  E-value: 2.71e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668   2 EKVEKIDNDKIVYMDEAGMDDTERYAYGHSAKGKRCYAEKPGKKSIRINFIGGLRGKQFIAPMMVEGYCNANVCQAYIDQ 81
Cdd:NF033545  136 LYRAPPDPAEVVFIDESGIQLLDTRGRGWAPKGQRRPRVHVYGRRGTLNLFGALDPLTGKVFVLFTGRINSEDFIEFLEE 215
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778926668  82 CLIPCLSPGETVIMDNASFHKSKGVKEAIEDAG-CHLLFLPPYSPDLNPIEHVWSPLKNRVRMKL---DQDEinLETALS 157
Cdd:NF033545  216 LLAAYPGKKIHLILDNASTHKSKKVREWLEEHGrIELHYLPPYSPWLNPIERVWAVLKRRLLRNRafrSVDE--LREAID 293

                  ....*
gi 1778926668 158 QVMKS 162
Cdd:NF033545  294 AFLNR 298
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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