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Conserved domains on  [gi|1768674981|emb|VWP73481|]
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proteasome maturation factor UMP1, putative [Plasmodium falciparum 3D7]

Protein Classification

proteasome maturation protein( domain architecture ID 9018)

proteasome maturation protein is a molecular chaperone essential for the assembly and maturation of proteasomes

Gene Ontology:  GO:0043248

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UMP1 super family cl05088
Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor ...
 49-122 7.02e-06

Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. UMP1 is required for the correct assembly and enzymatic activation of the proteasome. UMP1 seems to be degraded by the proteasome upon its formation


The actual alignment was detected with superfamily member pfam05348:

Pssm-ID: 461627  Cd Length: 115  Bit Score: 41.82  E-value: 7.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1768674981  49 LKRTGL--IYGSQEVYKNILDREIVSLSRRLPG-IKSSLLSLDIVRNTIDRIDSYEYMEKIDEHPLEP-LSEIIEKKM 122
Cdd:pfam05348  38 LKLEMLrnIYGLAEPLRRQMELKIVSQTDRLPGaLPSSNLHLDILTGRDDSIDWEDVLNDPEESEVMPdFHSEMERKL 115
 
Name Accession Description Interval E-value
UMP1 pfam05348
Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor ...
 49-122 7.02e-06

Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. UMP1 is required for the correct assembly and enzymatic activation of the proteasome. UMP1 seems to be degraded by the proteasome upon its formation


Pssm-ID: 461627  Cd Length: 115  Bit Score: 41.82  E-value: 7.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1768674981  49 LKRTGL--IYGSQEVYKNILDREIVSLSRRLPG-IKSSLLSLDIVRNTIDRIDSYEYMEKIDEHPLEP-LSEIIEKKM 122
Cdd:pfam05348  38 LKLEMLrnIYGLAEPLRRQMELKIVSQTDRLPGaLPSSNLHLDILTGRDDSIDWEDVLNDPEESEVMPdFHSEMERKL 115
 
Name Accession Description Interval E-value
UMP1 pfam05348
Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor ...
 49-122 7.02e-06

Proteasome maturation factor UMP1; UMP1 is a short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex. UMP1 is required for the correct assembly and enzymatic activation of the proteasome. UMP1 seems to be degraded by the proteasome upon its formation


Pssm-ID: 461627  Cd Length: 115  Bit Score: 41.82  E-value: 7.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1768674981  49 LKRTGL--IYGSQEVYKNILDREIVSLSRRLPG-IKSSLLSLDIVRNTIDRIDSYEYMEKIDEHPLEP-LSEIIEKKM 122
Cdd:pfam05348  38 LKLEMLrnIYGLAEPLRRQMELKIVSQTDRLPGaLPSSNLHLDILTGRDDSIDWEDVLNDPEESEVMPdFHSEMERKL 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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