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Conserved domains on  [gi|1768565114|ref|XP_031260466|]
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caffeoylshikimate esterase-like [Pistacia vera]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 9-322 1.57e-101

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02298:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 330  Bit Score: 301.31  E-value: 1.57e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114   9 ANENSPYGDLTREQFLKKHQILHQESYMFNKKNMKIFTQTWRPDSPGPLKGRVAMIHGYTSDGSWVSELTAVAIAKTGFL 88
Cdd:PLN02298   10 ETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  89 VCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDSVKTN--HPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGSMC 166
Cdd:PLN02298   90 CFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQReeFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMC 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 167 GVSAKFKPMWPLEKLLPVAALFAPKWKVVLSKPVASKSYKEEWKRRLVARNPnRRTSGKPPAATALEFLRVCEYIKRHCH 246
Cdd:PLN02298  170 KISDKIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNP-MRYNGKPRLGTVVELLRVTDYLGKKLK 248

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768565114 247 ELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWH-MLIGENEEDVEVVFGIVLSWIAERAGKAKAKS 322
Cdd:PLN02298  249 DVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHsLLFGEPDENIEIVRRDILSWLNERCTGKATPS 325
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 9-322 1.57e-101

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 301.31  E-value: 1.57e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114   9 ANENSPYGDLTREQFLKKHQILHQESYMFNKKNMKIFTQTWRPDSPGPLKGRVAMIHGYTSDGSWVSELTAVAIAKTGFL 88
Cdd:PLN02298   10 ETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  89 VCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDSVKTN--HPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGSMC 166
Cdd:PLN02298   90 CFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQReeFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMC 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 167 GVSAKFKPMWPLEKLLPVAALFAPKWKVVLSKPVASKSYKEEWKRRLVARNPnRRTSGKPPAATALEFLRVCEYIKRHCH 246
Cdd:PLN02298  170 KISDKIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNP-MRYNGKPRLGTVVELLRVTDYLGKKLK 248

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768565114 247 ELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWH-MLIGENEEDVEVVFGIVLSWIAERAGKAKAKS 322
Cdd:PLN02298  249 DVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHsLLFGEPDENIEIVRRDILSWLNERCTGKATPS 325
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 55-295 4.50e-72

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 222.86  E-value: 4.50e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  55 GPLKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDSVKTNHPKLPSF 134
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHL-ADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 135 LYGESLGGAISILICLEQKYEWDGLILSGSMCGVSAKFKPmWPLEKLLPVAALFAPKWKVVLSKPvASKSYKEEWKRRLV 214
Cdd:pfam12146  80 LLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAP-PILKLLAKLLGKLFPRLRVPNNLL-PDSLSRDPEVVAAY 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 215 ARNPNRRtsGKPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWHMLIG 294
Cdd:pfam12146 158 AADPLVH--GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLN 235


                  .
gi 1768565114 295 E 295
Cdd:pfam12146 236 E 236
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
43-313 6.39e-35

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 126.66  E-value: 6.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  43 KIFTQTWRPDSPGplKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFD 122
Cdd:COG2267    15 RLRGRRWRPAGSP--RGTVVLVHGLGEHSGRYAEL-AEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 123 SVKTnHPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGsmcgvsakfkPMWPLEKLLPVAALFapkwkvvlskpvas 202
Cdd:COG2267    92 ALRA-RPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLA----------PAYRADPLLGPSARW-------------- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 203 ksykeewkrrlvarnpnrrtsgkppaataLEFLRVCEYIKRhcheLEVPLLMLHGENDALCDYESARLVYESAeSEDKTL 282
Cdd:COG2267   147 -----------------------------LRALRLAEALAR----IDVPVLVLHGGADRVVPPEAARRLAARL-SPDVEL 192

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1768565114 283 KIFPGLWHMLIgeNEEDVEVVFGIVLSWIAE 313
Cdd:COG2267   193 VLLPGARHELL--NEPAREEVLAAILAWLER 221
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 67-311 1.80e-11

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 64.03  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  67 YTSDGSWVSELTavaiaKTGFLVCALDLQGHGSSDGY---PGHIPNIEHIVQDCIQF--------------------FDS 123
Cdd:TIGR01607  60 YIYKDSWIENFN-----KNGYSVYGLDLQGHGESDGLqnlRGHINCFDDLVYDVIQYmnrindsiilenetksddesYDI 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 124 VKTNHPKLPSFLYGESLGGAISI----LICLEQ----KYEWDGLI-LSGSM------CGVSAKFKPMW-PLEKLLP-VAA 186
Cdd:TIGR01607 135 VNTKENRLPMYIIGLSMGGNIALrlleLLGKSNenndKLNIKGCIsLSGMIsiksvgSDDSFKFKYFYlPVMNFMSrVFP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 187 LFAPKWKVVLSK-PVASKSYKEEwKRRLVARNPNRRTSGKPPAATALEflRVCEYIKRhchelEVPLLMLHGENDALCDY 265
Cdd:TIGR01607 215 TFRISKKIRYEKsPYVNDIIKFD-KFRYDGGITFNLASELIKATDTLD--CDIDYIPK-----DIPILFIHSKGDCVCSY 286

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1768565114 266 ESARLVYESAESEDKTLKIFPGLWHMLIGE--NEEdvevVFGIVLSWI 311
Cdd:TIGR01607 287 EGTVSFYNKLSISNKELHTLEDMDHVITIEpgNEE----VLKKIIEWI 330
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 9-322 1.57e-101

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 301.31  E-value: 1.57e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114   9 ANENSPYGDLTREQFLKKHQILHQESYMFNKKNMKIFTQTWRPDSPGPLKGRVAMIHGYTSDGSWVSELTAVAIAKTGFL 88
Cdd:PLN02298   10 ETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  89 VCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDSVKTN--HPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGSMC 166
Cdd:PLN02298   90 CFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQReeFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMC 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 167 GVSAKFKPMWPLEKLLPVAALFAPKWKVVLSKPVASKSYKEEWKRRLVARNPnRRTSGKPPAATALEFLRVCEYIKRHCH 246
Cdd:PLN02298  170 KISDKIRPPWPIPQILTFVARFLPTLAIVPTADLLEKSVKVPAKKIIAKRNP-MRYNGKPRLGTVVELLRVTDYLGKKLK 248

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768565114 247 ELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWH-MLIGENEEDVEVVFGIVLSWIAERAGKAKAKS 322
Cdd:PLN02298  249 DVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHsLLFGEPDENIEIVRRDILSWLNERCTGKATPS 325
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 55-295 4.50e-72

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 222.86  E-value: 4.50e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  55 GPLKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDSVKTNHPKLPSF 134
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHL-ADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLPLF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 135 LYGESLGGAISILICLEQKYEWDGLILSGSMCGVSAKFKPmWPLEKLLPVAALFAPKWKVVLSKPvASKSYKEEWKRRLV 214
Cdd:pfam12146  80 LLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAP-PILKLLAKLLGKLFPRLRVPNNLL-PDSLSRDPEVVAAY 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 215 ARNPNRRtsGKPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWHMLIG 294
Cdd:pfam12146 158 AADPLVH--GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELLN 235


                  .
gi 1768565114 295 E 295
Cdd:pfam12146 236 E 236
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 32-318 3.26e-62

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 201.52  E-value: 3.26e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  32 QESYMFNKKNMKIFTQTWRPDsPGPLKGRVAMIHGYTSDGSWVSELTAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIE 111
Cdd:PLN02385   62 EESYEVNSRGVEIFSKSWLPE-NSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFD 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 112 HIVQDCIQFFDSVKTN--HPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGSMCGVSAKFKPMWPLEKLLPVAALFA 189
Cdd:PLN02385  141 DLVDDVIEHYSKIKGNpeFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLL 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 190 PKWKVVLSKPVASKSYKEEWKRRLVARNPNRRTsGKPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESAR 269
Cdd:PLN02385  221 PKAKLVPQKDLAELAFRDLKKRKMAEYNVIAYK-DKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSK 299

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1768565114 270 LVYESAESEDKTLKIFPGLWHMLI-GENEEDVEVVFGIVLSWIAERAGKA 318
Cdd:PLN02385  300 FLYEKASSSDKKLKLYEDAYHSILeGEPDEMIFQVLDDIISWLDSHSTQK 349
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
43-313 6.39e-35

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 126.66  E-value: 6.39e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  43 KIFTQTWRPDSPGplKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFD 122
Cdd:COG2267    15 RLRGRRWRPAGSP--RGTVVLVHGLGEHSGRYAEL-AEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALD 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 123 SVKTnHPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGsmcgvsakfkPMWPLEKLLPVAALFapkwkvvlskpvas 202
Cdd:COG2267    92 ALRA-RPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLA----------PAYRADPLLGPSARW-------------- 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 203 ksykeewkrrlvarnpnrrtsgkppaataLEFLRVCEYIKRhcheLEVPLLMLHGENDALCDYESARLVYESAeSEDKTL 282
Cdd:COG2267   147 -----------------------------LRALRLAEALAR----IDVPVLVLHGGADRVVPPEAARRLAARL-SPDVEL 192

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1768565114 283 KIFPGLWHMLIgeNEEDVEVVFGIVLSWIAE 313
Cdd:COG2267   193 VLLPGARHELL--NEPAREEVLAAILAWLER 221
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 44-314 2.77e-27

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 109.98  E-value: 2.77e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  44 IFTQTWRPDSpGPLKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFFDS 123
Cdd:PLN02652  123 LFCRSWAPAA-GEMRGILIIIHGLNEHSGRYLHF-AKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDTEAFLEK 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 124 VKTNHPKLPSFLYGESLGGAISILICLEQKYE--WDGLILSGSmcgvSAKFKPMWPL-EKLLPVAALFAPKWKvvlskpv 200
Cdd:PLN02652  201 IRSENPGVPCFLFGHSTGGAVVLKAASYPSIEdkLEGIVLTSP----ALRVKPAHPIvGAVAPIFSLVAPRFQ------- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 201 asksYKEEWKRRL-VARNPNRRT---------SGKPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESARL 270
Cdd:PLN02652  270 ----FKGANKRGIpVSRDPAALLakysdplvyTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADRVTDPLASQD 345

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1768565114 271 VYESAESEDKTLKIFPGLWHMLIGENEEDvEVVFGIVlSWIAER 314
Cdd:PLN02652  346 LYNEAASRHKDIKLYDGFLHDLLFEPERE-EVGRDII-DWMEKR 387
PHA02857 PHA02857
monoglyceride lipase; Provisional
 35-315 2.03e-24

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 99.96  E-value: 2.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  35 YMFNKKNMKIFTQTWRPdSPGPlKGRVAMIHGyTSDGSWVSELTAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIV 114
Cdd:PHA02857    4 CMFNLDNDYIYCKYWKP-ITYP-KALVFISHG-AGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 115 QDCIQFFDSVKTNHPKLPSFLYGESLGGAISILICLEQKYEWDGLILSGSMcgVSAKFKPMWPLEKLLPVAALFAPKWKV 194
Cdd:PHA02857   81 RDVVQHVVTIKSTYPGVPVFLLGHSMGATISILAAYKNPNLFTAMILMSPL--VNAEAVPRLNLLAAKLMGIFYPNKIVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 195 VLSKPVASKSYKEEWKRRLvarNPnRRTSGKPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESARLVYES 274
Cdd:PHA02857  159 KLCPESVSRDMDEVYKYQY---DP-LVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFMQH 234

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1768565114 275 AESeDKTLKIFPGLWHMLIGENEEDVEVVFGIVLSWIAERA 315
Cdd:PHA02857  235 ANC-NREIKIYEGAKHHLHKETDEVKKSVMKEIETWIFNRV 274
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
61-316 7.43e-24

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 97.70  E-value: 7.43e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  61 VAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSdgyPGHIPN--IEHIVQDCIQFFDSVKTNHPKLpsFLYGE 138
Cdd:COG1647    18 VLLLHGFTGSPAEMRPL-AEALAKAGYTVYAPRLPGHGTS---PEDLLKttWEDWLEDVEEAYEILKAGYDKV--IVIGL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 139 SLGGAISILICLEQKyEWDGLILsgsmcgVSAKFKPMWPLEKLLPVAALFAPKWKVVLSKPVASKSYKEEWKRRlvarnp 218
Cdd:COG1647    92 SMGGLLALLLAARYP-DVAGLVL------LSPALKIDDPSAPLLPLLKYLARSLRGIGSDIEDPEVAEYAYDRT------ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 219 nrrtsgkpPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCDYESARLVYESAESEDKTLKIFPGLWHMLIgeNEE 298
Cdd:COG1647   159 --------PLRALAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVIT--LDK 228

                         250
                  ....*....|....*...
gi 1768565114 299 DVEVVFGIVLSWIAERAG 316
Cdd:COG1647   229 DREEVAEEILDFLERLAA 246
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
50-313 3.03e-16

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 76.59  E-value: 3.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  50 RPDSPGPLKGrVAMIHGYTSDGSWVSELTAVAIAKTGFLVCALDLQGHGSSDGYPGHIPniehiVQDCIQFFDSVKtNHP 129
Cdd:COG1506    16 LPADGKKYPV-VVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDE-----VDDVLAAIDYLA-ARP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 130 KLPS---FLYGESLGGAISILICLEQKYEWDGLIlsgSMCGVSAkFKPMWPLEKLLPVAALFAPkwkvvlskpvasksyk 206
Cdd:COG1506    89 YVDPdriGIYGHSYGGYMALLAAARHPDRFKAAV---ALAGVSD-LRSYYGTTREYTERLMGGP---------------- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 207 EEWKRRLVARNPnrrtsgkppaataleflrvceyiKRHCHELEVPLLMLHGENDALCDYESARLVYESAES--EDKTLKI 284
Cdd:COG1506   149 WEDPEAYAARSP-----------------------LAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKagKPVELLV 205

                         250       260
                  ....*....|....*....|....*....
gi 1768565114 285 FPGLWHMLIGENEEDvevVFGIVLSWIAE 313
Cdd:COG1506   206 YPGEGHGFSGAGAPD---YLERILDFLDR 231
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 23-291 9.16e-15

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 72.64  E-value: 9.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  23 FLKKHQILHQESYMFNKKNMKIFTQTWRPDSPGPLKGRVAMIHGYTSDGSWVSELtAVAIAKTGFLVCALDLQGHGSSDG 102
Cdd:COG1073     2 FPPSDKVNKEDVTFKSRDGIKLAGDLYLPAGASKKYPAVVVAHGNGGVKEQRALY-AQRLAELGFNVLAFDYRGYGESEG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 103 YPGHIPNIEhiVQDCIQFFDSVKTnHPKLPS---FLYGESLGGAISILICLEQKYewdglilsgsmcgvsakfkpmwple 179
Cdd:COG1073    81 EPREEGSPE--RRDARAAVDYLRT-LPGVDPeriGLLGISLGGGYALNAAATDPR------------------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 180 kllpVAAlfapkwkVVLSKPVASksyKEEWKRRLVARNPNRRTSGKP--PAATALEFLR----VCEYIKRhcheLEVPLL 253
Cdd:COG1073   133 ----VKA-------VILDSPFTS---LEDLAAQRAKEARGAYLPGVPylPNVRLASLLNdefdPLAKIEK----ISRPLL 194

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1768565114 254 MLHGENDALCDYESARLVYESAeSEDKTLKIFPGLWHM 291
Cdd:COG1073   195 FIHGEKDEAVPFYMSEDLYEAA-AEPKELLIVPGAGHV 231
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 41-314 4.99e-13

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 67.33  E-value: 4.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  41 NMKIFTQTWRPDSPgplkgRVAMIHGYTSDG-SWVSELTAVAiakTGFLVCALDLQGHGSSDGyPGHIPNIEHIVQDCIQ 119
Cdd:COG0596    11 GVRLHYREAGPDGP-----PVVLLHGLPGSSyEWRPLIPALA---AGYRVIAPDLRGHGRSDK-PAGGYTLDDLADDLAA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 120 FFDSVKTNhpklPSFLYGESLGGAISILICLEQKYEWDGLILSGSMcgvsakfkpmwplekllpvaalfapkwkvvlskp 199
Cdd:COG0596    82 LLDALGLE----RVVLVGHSMGGMVALELAARHPERVAGLVLVDEV---------------------------------- 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 200 vasksykeewkRRLVARNPNRRTSGKPPAATALEFLRVCEYIKRHcHELEVPLLMLHGENDALCDYESARLVYESAesED 279
Cdd:COG0596   124 -----------LAALAEPLRRPGLAPEALAALLRALARTDLRERL-ARITVPTLVIWGEKDPIVPPALARRLAELL--PN 189

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1768565114 280 KTLKIFPGLWHMLigeNEEDVEVVFGIVLSWIAER 314
Cdd:COG0596   190 AELVVLPGAGHFP---PLEQPEAFAAALRDFLARL 221
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 67-311 1.80e-11

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 64.03  E-value: 1.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  67 YTSDGSWVSELTavaiaKTGFLVCALDLQGHGSSDGY---PGHIPNIEHIVQDCIQF--------------------FDS 123
Cdd:TIGR01607  60 YIYKDSWIENFN-----KNGYSVYGLDLQGHGESDGLqnlRGHINCFDDLVYDVIQYmnrindsiilenetksddesYDI 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 124 VKTNHPKLPSFLYGESLGGAISI----LICLEQ----KYEWDGLI-LSGSM------CGVSAKFKPMW-PLEKLLP-VAA 186
Cdd:TIGR01607 135 VNTKENRLPMYIIGLSMGGNIALrlleLLGKSNenndKLNIKGCIsLSGMIsiksvgSDDSFKFKYFYlPVMNFMSrVFP 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 187 LFAPKWKVVLSK-PVASKSYKEEwKRRLVARNPNRRTSGKPPAATALEflRVCEYIKRhchelEVPLLMLHGENDALCDY 265
Cdd:TIGR01607 215 TFRISKKIRYEKsPYVNDIIKFD-KFRYDGGITFNLASELIKATDTLD--CDIDYIPK-----DIPILFIHSKGDCVCSY 286

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1768565114 266 ESARLVYESAESEDKTLKIFPGLWHMLIGE--NEEdvevVFGIVLSWI 311
Cdd:TIGR01607 287 EGTVSFYNKLSISNKELHTLEDMDHVITIEpgNEE----VLKKIIEWI 330
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 63-298 2.48e-08

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 53.63  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  63 MIHGYTSDGSWVSELTAvaiakTGFLVCALDLQGHGSSDGYPGHIPNiehiVQDCIQFFDSVKTNHPKlpsFLYGESLGG 142
Cdd:pfam12697   3 LVHGAGLSAAPLAALLA-----AGVAVLAPDLPGHGSSSPPPLDLAD----LADLAALLDELGAARPV---VLVGHSLGG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 143 AISILicLEQKYEWDGLILSGSMCGVSAKFKPMWPLEKLLPVAALFAPKWKVVLSKPVASK-SYKEEWKRRLVARnpnrr 221
Cdd:pfam12697  71 AVALA--AAAAALVVGVLVAPLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDlPADAEWAAALARL----- 143

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1768565114 222 tsgkPPAATALEFLRVCEYikrhcHELEVPLLMLHGEnDALCDYESARLVyesAESEDKTLKIFPGLWHMLIGENEE 298
Cdd:pfam12697 144 ----AALLAALALLPLAAW-----RDLPVPVLVLAEE-DRLVPELAQRLL---AALAGARLVVLPGAGHLPLDDPEE 207
PRK10749 PRK10749
lysophospholipase L2; Provisional
 86-264 4.87e-06

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 47.69  E-value: 4.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  86 GFLVCALDLQGHGSS-----DGYPGHIPNIEHIVQDCIQFFDSVKTNHPKLPSFLYGESLGGAISILICLEQKYEWDGLI 160
Cdd:PRK10749   81 GYDVLIIDHRGQGRSgrlldDPHRGHVERFNDYVDDLAAFWQQEIQPGPYRKRYALAHSMGGAILTLFLQRHPGVFDAIA 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 161 LSGSMCGVSAKFkPMWPLEKLLPVA----------ALFAPKWKVVlskP----VASKSYkEEWKR--RLVARNPNRRTSG 224
Cdd:PRK10749  161 LCAPMFGIVLPL-PSWMARRILNWAeghprirdgyAIGTGRWRPL---PfainVLTHSR-ERYRRnlRFYADDPELRVGG 235

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1768565114 225 kPPAATALEFLRVCEYIKRHCHELEVPLLMLHGENDALCD 264
Cdd:PRK10749  236 -PTYHWVRESILAGEQVLAGAGDITTPLLLLQAEEERVVD 274
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 63-296 1.01e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.88  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  63 MIHGYTsDGSWVSELTAVAIAKTGFLVCALDLQGHGSSDGYPGHIPNIEHIVQDCIQFF-DsvKTNHPKLpsFLYGESLG 141
Cdd:pfam00561   5 LLHGLP-GSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYIlE--ALGLEKV--NLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 142 GAISILICLEQKYEWDGLILSGSMC---------GVSAKFKPMW----PLEKLLPVAALFAPKWKVVLSKPVASKSYKEE 208
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGALDppheldeadRFILALFPGFfdgfVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 209 WKRRLVARNPNRRTSGKPPAATALEFLRVCEYIKRhCHELEVPLLMLHGENDALCDYESARlvYESAESEDKTLKIFPGL 288
Cdd:pfam00561 160 LNKRFPSGDYALAKSLVTGALLFIETWSTELRAKF-LGRLDEPTLIIWGDQDPLVPPQALE--KLAQLFPNARLVVIPDA 236


                  ....*...
gi 1768565114 289 WHMLIGEN 296
Cdd:pfam00561 237 GHFAFLEG 244
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 61-145 3.76e-03

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 38.77  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  61 VAMIHGYTSDG-SWVSELTAVAIAKTgflVCALDLQGHGSSDGYPGHiPNIEHIVQDCIQFFDSVKTNhpklPSFLYGES 139
Cdd:PRK14875  134 VVLIHGFGGDLnNWLFNHAALAAGRP---VIALDLPGHGASSKAVGA-GSLDELAAAVLAFLDALGIE----RAHLVGHS 205


                  ....*.
gi 1768565114 140 LGGAIS 145
Cdd:PRK14875  206 MGGAVA 211
COG4757 COG4757
Predicted alpha/beta hydrolase [General function prediction only];
79-263 4.20e-03

Predicted alpha/beta hydrolase [General function prediction only];


Pssm-ID: 443790 [Multi-domain]  Cd Length: 289  Bit Score: 38.33  E-value: 4.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114  79 AVAIAKTGFLVCALDLQGHGSSDgyPGHIPNIEH-----IVQDCIQFFDSVKTNHPKLPSFLYGESLGGaisILICLEQK 153
Cdd:COG4757    52 ARYLAERGFAVLTYDYRGIGLSR--PGSLRGFDAgyrdwGELDLPAVLDALRARFPGLPLLLVGHSLGG---QLLGLAPN 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1768565114 154 YEW-DGLILSGSMCGVSAKFKP--------MWPLekLLPVAALF-----APKWKVV--LSKPVAsksykEEWKRRlvARN 217
Cdd:COG4757   127 AERvDRLVTVASGSGYWRDYPPrrrlkvllFWHL--LGPLLTRLlgyfpGRRLGFGedLPAGVA-----RQWRRW--CRR 197

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1768565114 218 PNRRTSGKPPAATAleflrvceyikrHCHELEVPLLMLHGENDALC 263
Cdd:COG4757   198 PRYFFDDDGEDLEA------------ALAAVTAPVLAISFTDDELA 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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