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Conserved domains on  [gi|17570810|ref|NP_523319|]
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hypothetical protein T3p24 [Enterobacteria phage T3]

Protein Classification

PHA00446 family protein( domain architecture ID 10009706)

PHA00446 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA00446 PHA00446
hypothetical protein
 8-92 1.75e-43

hypothetical protein


:

Pssm-ID: 177281  Cd Length: 89  Bit Score: 136.14  E-value: 1.75e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570810   8 ANTIRLPDTADQFARRVHINVRGEKVTMVYRWKDHKSPKAHTQRMTLDDKQVGRLMGALTMAADNVVGDNRERLVEFGAG 87
Cdd:PHA00446  5 ANTIRLSDTADQWARRVHINVRNGKVTMVYRWKDHKSSKAHTQRMTLDDEQAGRLLAALTVAATVAVGDNKVRNVALGKG 84


                ....*
gi 17570810  88 MQEII 92
Cdd:PHA00446 85 VKEII 89
 
Name Accession Description Interval E-value
PHA00446 PHA00446
hypothetical protein
 8-92 1.75e-43

hypothetical protein


Pssm-ID: 177281  Cd Length: 89  Bit Score: 136.14  E-value: 1.75e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570810   8 ANTIRLPDTADQFARRVHINVRGEKVTMVYRWKDHKSPKAHTQRMTLDDKQVGRLMGALTMAADNVVGDNRERLVEFGAG 87
Cdd:PHA00446  5 ANTIRLSDTADQWARRVHINVRNGKVTMVYRWKDHKSSKAHTQRMTLDDEQAGRLLAALTVAATVAVGDNKVRNVALGKG 84


                ....*
gi 17570810  88 MQEII 92
Cdd:PHA00446 85 VKEII 89
TA_inhibitor pfam17574
Inhibitor of toxin/antitoxin system (Gp4.5); This is a family of prokaryotic toxin-antitoxin ...
 8-70 6.48e-25

Inhibitor of toxin/antitoxin system (Gp4.5); This is a family of prokaryotic toxin-antitoxin (TA) systems inhibitors, found in Podoviridae such as Enterobacteria phage T7. Family members such as Gene product 4.5 have been shown to neutralize TA-system-mediated abortive infection by inhibiting the Lon protease activity, thus preventing antitoxin degradation and toxin activation.


Pssm-ID: 340289  Cd Length: 89  Bit Score: 89.10  E-value: 6.48e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17570810    8 ANTIRLPDTADQFARRVHINVRGEKVTMVYRWKDHKSPKAHTQRMTLDDKQVGRLMGALTMAA 70
Cdd:pfam17574  5 AETIRLSDTADQWNRRVHINVRNGKATMVYRWKDSKSSKNHTQRMTLTDEQALRLVNALTKAA 67
 
Name Accession Description Interval E-value
PHA00446 PHA00446
hypothetical protein
 8-92 1.75e-43

hypothetical protein


Pssm-ID: 177281  Cd Length: 89  Bit Score: 136.14  E-value: 1.75e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17570810   8 ANTIRLPDTADQFARRVHINVRGEKVTMVYRWKDHKSPKAHTQRMTLDDKQVGRLMGALTMAADNVVGDNRERLVEFGAG 87
Cdd:PHA00446  5 ANTIRLSDTADQWARRVHINVRNGKVTMVYRWKDHKSSKAHTQRMTLDDEQAGRLLAALTVAATVAVGDNKVRNVALGKG 84


                ....*
gi 17570810  88 MQEII 92
Cdd:PHA00446 85 VKEII 89
TA_inhibitor pfam17574
Inhibitor of toxin/antitoxin system (Gp4.5); This is a family of prokaryotic toxin-antitoxin ...
 8-70 6.48e-25

Inhibitor of toxin/antitoxin system (Gp4.5); This is a family of prokaryotic toxin-antitoxin (TA) systems inhibitors, found in Podoviridae such as Enterobacteria phage T7. Family members such as Gene product 4.5 have been shown to neutralize TA-system-mediated abortive infection by inhibiting the Lon protease activity, thus preventing antitoxin degradation and toxin activation.


Pssm-ID: 340289  Cd Length: 89  Bit Score: 89.10  E-value: 6.48e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17570810    8 ANTIRLPDTADQFARRVHINVRGEKVTMVYRWKDHKSPKAHTQRMTLDDKQVGRLMGALTMAA 70
Cdd:pfam17574  5 AETIRLSDTADQWNRRVHINVRNGKATMVYRWKDSKSSKNHTQRMTLTDEQALRLVNALTKAA 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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