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Conserved domains on  [gi|1755203663|ref|NP_001361438|]
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cyclin-dependent kinase inhibitor 1 isoform 2 [Homo sapiens]

Protein Classification

cyclin-dependent kinase inhibitor( domain architecture ID 10491403)

cyclin-dependent kinase inhibitor is an important regulator of cell cycle progression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 55-100 9.60e-19

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


:

Pssm-ID: 460503  Cd Length: 46  Bit Score: 75.64  E-value: 9.60e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1755203663  55 LFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWE 100
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPLPGRYEWE 46
 
Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 55-100 9.60e-19

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


Pssm-ID: 460503  Cd Length: 46  Bit Score: 75.64  E-value: 9.60e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1755203663  55 LFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWE 100
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPLPGRYEWE 46
 
Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 55-100 9.60e-19

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


Pssm-ID: 460503  Cd Length: 46  Bit Score: 75.64  E-value: 9.60e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1755203663  55 LFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWE 100
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPLPGRYEWE 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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