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Conserved domains on  [gi|1735107642|gb|QEM15350|]
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RNA polymerase sigma-70 factor [Mucilaginibacter gossypii]

Protein Classification

RNA polymerase sigma-70 factor( domain architecture ID 11496275)

RNA polymerase sigma-70 factor; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 25-179 2.65e-47

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


:

Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 152.33  E-value: 2.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKL 103
Cdd:TIGR02985   2 AFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEiSESIKAYLFTIVKNRCLNYLRHKQVEEKYQEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 104 EEL----FSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:TIGR02985  82 AEIeereLSEADPEEELEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKALKFLRKEL 161
 
Name Accession Description Interval E-value
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 25-179 2.65e-47

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 152.33  E-value: 2.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKL 103
Cdd:TIGR02985   2 AFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEiSESIKAYLFTIVKNRCLNYLRHKQVEEKYQEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 104 EEL----FSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:TIGR02985  82 AEIeereLSEADPEEELEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKALKFLRKEL 161
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 10-182 8.03e-44

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 143.98  E-value: 8.03e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFN 88
Cdd:COG1595     3 SDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRgRGSFRAWLYRIARNLAID 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADLFNKLEELF--SNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVEN 166
Cdd:COG1595    83 HLRKRRRRRELLDELAEELpdEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKS 162

                         170
                  ....*....|....*.
gi 1735107642 167 QLTVALNRLRKTLGDF 182
Cdd:COG1595   163 RLSRARKKLREALEEE 178
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
 10-183 6.26e-26

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 98.59  E-value: 6.26e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRA-NLKLTSLNAYLYTSVRYQVFN 88
Cdd:PRK12519   15 SDAELFSALKAGQSAALGVLYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSSyDPKRGSLSSYLLTLTRSRAID 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADLFNKLEELFSNNGGE----ELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTV 164
Cdd:PRK12519   95 RLRSRRSRQRLLERWQQELLGEASEdtplEQASLAERSQRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTV 174

                         170
                  ....*....|....*....
gi 1735107642 165 ENQLTVALNRLRKTLGDFV 183
Cdd:PRK12519  175 KARARQGLLKLRELLQDLL 193
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
 123-175 4.60e-10

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 53.23  E-value: 4.60e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1735107642 123 RLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:pfam08281   2 EALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
 122-176 2.66e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 40.17  E-value: 2.66e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 122 NRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLR 176
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 148-175 8.02e-05

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 39.05  E-value: 8.02e-05
                           10        20
                   ....*....|....*....|....*...
gi 1735107642  148 LSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:smart00421  19 LTNKEIAERLGISEKTVKTHLSNIMRKL 46
 
Name Accession Description Interval E-value
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
 25-179 2.65e-47

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 152.33  E-value: 2.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKL 103
Cdd:TIGR02985   2 AFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEiSESIKAYLFTIVKNRCLNYLRHKQVEEKYQEEL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 104 EEL----FSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:TIGR02985  82 AEIeereLSEADPEEELEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKALKFLRKEL 161
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
 10-182 8.03e-44

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 143.98  E-value: 8.03e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFN 88
Cdd:COG1595     3 SDEELLERLRAGDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRgRGSFRAWLYRIARNLAID 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADLFNKLEELF--SNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVEN 166
Cdd:COG1595    83 HLRKRRRRRELLDELAEELpdEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKS 162

                         170
                  ....*....|....*.
gi 1735107642 167 QLTVALNRLRKTLGDF 182
Cdd:COG1595   163 RLSRARKKLREALEEE 178
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
 25-179 1.68e-26

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 98.96  E-value: 1.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKL-TSLNAYLYTSVRYQVFNVIRSGKVRADLFNKL 103
Cdd:TIGR02937   2 AFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPeGSFKAWLFRIARNLILDYLRRKRRLRRELDLL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735107642 104 EELFSN-NGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:TIGR02937  82 EELLDSdPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
 10-183 6.26e-26

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 98.59  E-value: 6.26e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRA-NLKLTSLNAYLYTSVRYQVFN 88
Cdd:PRK12519   15 SDAELFSALKAGQSAALGVLYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSSyDPKRGSLSSYLLTLTRSRAID 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADLFNKLEELFSNNGGE----ELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTV 164
Cdd:PRK12519   95 RLRSRRSRQRLLERWQQELLGEASEdtplEQASLAERSQRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTV 174

                         170
                  ....*....|....*....
gi 1735107642 165 ENQLTVALNRLRKTLGDFV 183
Cdd:PRK12519  175 KARARQGLLKLRELLQDLL 193
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
 25-181 3.49e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 85.79  E-value: 3.49e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLT-SLNAYLYTSVRYQVFNVIRSGKVRADLFNKL 103
Cdd:PRK11924   14 AFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKgSARTWLLTIARNVCYDLLRRRRREKAVLSDD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 104 ----EELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK11924   94 alepEFAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLRECL 173


                  ..
gi 1735107642 180 GD 181
Cdd:PRK11924  174 EA 175
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
 10-180 1.17e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 77.70  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFN 88
Cdd:PRK11922   16 SDRELVARVLAGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRgDASLSTWLSRIVLNEALG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADL-----------FNKLEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERL 157
Cdd:PRK11922   96 RLRRRRRLVNLaemvmastiagGERTPLADPAEDPERAAARREIRALLERAIDALPDAFRAVFVLRVVEELSVEETAQAL 175

                         170       180
                  ....*....|....*....|...
gi 1735107642 158 GIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK11922  176 GLPEETVKTRLHRARRLLRESLA 198
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
 15-181 3.26e-16

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 72.53  E-value: 3.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  15 IALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKL-TSLNAYLYTSVRYQVFNVIRSG 93
Cdd:PRK09652    1 VERVQRGDRAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGgAAFYTWLYRIARNTAINYLRKQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  94 KVR----------ADLFNKLEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKT 163
Cdd:PRK09652   81 GRRppasdvdaeeAEDFDLADALRDISTPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGT 160

                         170
                  ....*....|....*...
gi 1735107642 164 VENQLTVALNRLRKTLGD 181
Cdd:PRK09652  161 VRSRIFRAREALRAKLQP 178
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
 26-179 5.13e-15

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 69.21  E-value: 5.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  26 FERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNL----WMKRANLKltslnAYLYTSVRYQVFNVIRSGKVRAdlfN 101
Cdd:PRK09639    5 FEDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLyrsdFKGIENEK-----GWLIKSARNVAYNYLRSEKRRR---A 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 102 KLEELFSNNGG------EELLSEKEINRLLEQGVAELPEKCRQIFIMsRKEHLSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:PRK09639   77 RILGEFQWQEVdnepspEEIWIRKEEITKVQEVLAKMTERDRTVLLL-RFSGYSYKEIAEALGIKESSVGTTLARAKKKF 155


                  ....
gi 1735107642 176 RKTL 179
Cdd:PRK09639  156 RKIY 159
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
 10-179 9.57e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 68.95  E-value: 9.57e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNL------WMKRAnlkltSLNAYLYTSVR 83
Cdd:PRK12513   12 SDEALMLRYRAGDAAAFEALYARHRTGLYRFLLRLARDRALAEDIFQETWLRViraraqYQPRA-----RFRTWLYQIAR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  84 yqvfNVI-----RSGKVRADLFNKLEELFS----NNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIA 154
Cdd:PRK12513   87 ----NLLidhwrRHGARQAPSLDADEQLHAladdGAAPEQQLSLFRDRRRLQAALETLPDEQREVFLLREHGDLELEEIA 162

                         170       180
                  ....*....|....*....|....*
gi 1735107642 155 ERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK12513  163 ELTGVPEETVKSRLRYALQKLRELL 187
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
 1-179 2.75e-12

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 62.07  E-value: 2.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   1 MNSLEVQLMTDEDLIALIREndlgaferIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLY 79
Cdd:PRK09415    1 MEELTIEAFEIEDKEDLIDE--------IMNEYGQEVLQLVYSYVKNKEVAEDLTQEIFVKCYKSLHTYKgKSSLKTWLY 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  80 TSVRYQVFNVIRSGKVRADLFNklEELFSNNGGEELLSEKEI------NRLLEQgVAELPEKCRQIFIMSRKEHLSTKEI 153
Cdd:PRK09415   73 RIAINHCKDYLKSWHNKKVIVT--EDIFTYMESQKESVEEEViqnaedERLASA-VMSLPIKYREVIYLFYYEELSIKEI 149

                         170       180
                  ....*....|....*....|....*.
gi 1735107642 154 AERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK09415  150 AEVTGVNENTVKTRLKKAKELLKKGL 175
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
 24-180 1.30e-11

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 60.10  E-value: 1.30e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  24 GAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYlytsVRYQVFNVIRSGKVRADLFNK 102
Cdd:TIGR02983   6 EEFTAFVAARYPRLLRTAYLLTGDPHEAEDLVQEALVRTYVRWDRIRdPDAPDAY----VRRVLVNLARSRWRRRRLLEL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1735107642 103 LEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:TIGR02983  82 PTRELPDAAAPDPAPDVALRAALARALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLSRALARLRELLE 159
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
 11-181 4.03e-11

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 59.28  E-value: 4.03e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  11 DEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK--LTSLNAYLYTSVRYQVFN 88
Cdd:PRK05602    7 DEELLARVAAGDPAAFRVLVARKLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRpgEARFDTWLHRVVLNLCYD 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRsgKVRADLFNKLEELFSNN-GGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQ 167
Cdd:PRK05602   87 RLR--RRREVPVEDAPDVPDPApGPDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVDALESL 164

                         170
                  ....*....|....
gi 1735107642 168 LTVALNRLRKTLGD 181
Cdd:PRK05602  165 LARGRRALRAQLAD 178
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
 47-176 4.06e-11

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 58.63  E-value: 4.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  47 DRQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGKVRAdlFNKLEELFSNNGGEELLSEKEINR--- 123
Cdd:PRK12527   18 NRQAAEDVAHDAYLRVLERSSSAQIEHPRAFLYRTALNLVVDRHRRHRVRQ--AEPLEVLDEEERLHSPSPQTRLDLgqr 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 124 --LLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLR 176
Cdd:PRK12527   96 laLLQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGISRSLVEKHIVNAMKHCR 150
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
 9-181 7.16e-11

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 58.55  E-value: 7.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   9 MTDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQE----VLVNLWMKRANLKLTSlnaYLYTSVRY 84
Cdd:PRK09641    3 LLIKRLIKQVKKGDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEafirAYVNIDSYDINRKFST---WLYRIATN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  85 QVFNVIRsgKVRADLFnkLEELFSNNGG--------------EELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLST 150
Cdd:PRK09641   80 LTIDRLR--KRKPDYY--LDAEVAGTEGltmysqlaaddalpEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSL 155

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1735107642 151 KEIAERLGIAPKTVENQLTVALNRLRKTLGD 181
Cdd:PRK09641  156 KEISEILDLPVGTVKTRIHRGREALRKQLRH 186
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
37-179 9.89e-11

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 57.78  E-value: 9.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  37 LYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLT--SLNAYLYTSVRYQVFNVIRSGKVRADlfnklEELFSNNGGEE 114
Cdd:PRK09645   22 LWRYALRLTGDRARAEDVVQETLLRAWQHPEVLADTgrSARAWLFTVARNLVIDERRSARARPV-----EGGDDVLGVPE 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 115 LLSEKEINRLLE-----QGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK09645   97 QSAPDEVDRALDrllvaDALAQLSPEHRAVLVRSYYRGWSTAQIAADLGIPEGTVKSRLHYALRALRLAL 166
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
 18-177 1.05e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 57.82  E-value: 1.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  18 IRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWmkranlklTSLNAY---------LYTSVRYQVFN 88
Cdd:PRK12543    1 MLSGDQEAFSEIYDVTIQEVYKTVHFLVEDKQDVDDVVNEIYIQLW--------ESLRKYdsnrpfrfwLIGLVIKQIHS 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRSGKVRADLFNKLEEL---FSNNGGEELLsEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVE 165
Cdd:PRK12543   73 WRRKRWRRFRIFEKAEEQrkpVSIDFSEDVL-SKESNQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVK 151

                         170
                  ....*....|..
gi 1735107642 166 NQLTVALNRLRK 177
Cdd:PRK12543  152 SRIHAALKKLRQ 163
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
 13-179 3.56e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 56.86  E-value: 3.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  13 DLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKrANL---KLTSLNAYLYTSVRYQVFNV 89
Cdd:PRK12531   16 ECMEKVKSRDKQAFALVFSYYAPKLKQFAMKHVGNEQVAMEMVQETMSTVWQK-AHLfdgQKSALSTWIYTIIRNLCFDL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  90 IRSGKVRaDLFNKLEELFSNN----------GGEELLSEKEINRLLEQgvaeLPEKCRQIFIMSRKEHLSTKEIAERLGI 159
Cdd:PRK12531   95 LRKQKGK-DLHIHADDIWPSDyyppdlvdhySPEQDMLKEQVMKFLDR----LPKAQRDVLQAVYLEELPHQQVAEMFDI 169

                         170       180
                  ....*....|....*....|
gi 1735107642 160 APKTVENQLTVALNRLRKTL 179
Cdd:PRK12531  170 PLGTVKSRLRLAVEKLRHSM 189
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
 5-166 4.56e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 56.44  E-value: 4.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   5 EVQLMTDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKL--TSLNAYLYTSV 82
Cdd:PRK12524    7 ALSDVSDEALLVLYANGDPAAARALTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRQgeARVSTWLYRVV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  83 RYQVFNVIRSGK-VRADLFNKLEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAP 161
Cdd:PRK12524   87 CNLCTDRLRRRRrASVDLDDAPEPADAAPGAEEALIEGDRMRALDAALAALPERQRQAVVLRHIEGLSNPEIAEVMEIGV 166


                  ....*
gi 1735107642 162 KTVEN 166
Cdd:PRK12524  167 EAVES 171
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
 123-175 4.60e-10

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 53.23  E-value: 4.60e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1735107642 123 RLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:pfam08281   2 EALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
 11-179 1.23e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 55.63  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  11 DEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK--LTSLNAYLYTSVRYQVFN 88
Cdd:PRK12538   50 DEELLDRLATDDEAAFRLLVERHIDRAYAIALRIVGNRADAEDVVQDTMLKVWTHRGRWQhgRAKFSTWLYRVVSNRCID 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  89 VIRsgKVRADLFNKLEELFSNN-GGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQ 167
Cdd:PRK12538  130 LRR--KPRTENVDAVPEVADGKpDAVSVIERNELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVESL 207

                         170
                  ....*....|..
gi 1735107642 168 LTVALNRLRKTL 179
Cdd:PRK12538  208 LKRGRQQLRDLL 219
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
 103-181 2.55e-09

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 54.83  E-value: 2.55e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1735107642 103 LEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLGD 181
Cdd:COG1191   158 LLDLLESGDPEEELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSESRVSRLHKKALARLREYLKE 236
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
 7-181 4.18e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 53.58  E-value: 4.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   7 QLMTDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQ 85
Cdd:PRK12515    5 QATTDEMLLARIAQGDRTAMQTLYGRHHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFEgRSQVSTWLLSIARFK 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  86 VFNVIRSGK---VRADLFNKLEElfSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPK 162
Cdd:PRK12515   85 ALSALRRRKheeIDDEAAAAIED--GADTPEVALQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPES 162

                         170
                  ....*....|....*....
gi 1735107642 163 TVENQLTVAlnrlRKTLGD 181
Cdd:PRK12515  163 TVKTRMFYA----RKKLAE 177
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
 18-180 4.33e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 53.52  E-value: 4.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  18 IRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWM---KRANLKLTSLNAYLYTSVRYQVFNVIRSGK 94
Cdd:PRK12542    3 VTNNDYEKMEELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLYKnleKLHSLNTQELKRYILRVAKNKAIDSYRKNK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  95 VRADLFNKLE----ELFSNNGGE---ELLSEKEINRLLEqgvaELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQ 167
Cdd:PRK12542   83 RHETFLEEYEresiEAVDENIEEwekRKMSEVQIDTLLK----ELNESNRQVFKYKVFYNLTYQEISSVMGITEANVRKQ 158

                         170
                  ....*....|...
gi 1735107642 168 LTVALNRLRKTLG 180
Cdd:PRK12542  159 FERARKRVQNMIG 171
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
 1-180 4.60e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 53.63  E-value: 4.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   1 MNSLEVQLMTDEDLIALIReNDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANL--KLTSLNAYL 78
Cdd:PRK12537    1 MSSPEAPFDYEACLLACAR-GDRRALQALYQQESARLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFdpARGSARGWI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  79 YTSVRYQVFNVIRsgkvradlfNKLEELFSNNGGEELLSEKE--------------INRLLEQgvaeLPEKCRQIFIMSR 144
Cdd:PRK12537   80 YSVTRHLALNVLR---------DTRREVVLDDDAEETAQTLHeiiddfdlwansgkIHRCLEQ----LEPARRNCILHAY 146

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1735107642 145 KEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK12537  147 VDGCSHAEIAQRLGAPLGTVKAWIKRSLKALRECMG 182
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
 27-159 8.92e-09

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 52.68  E-value: 8.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  27 ERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFNVIRSGKVRADLfnkLEE 105
Cdd:PRK09637    4 ESIWSEYKAQLKAFLHSRVSNEADVDDLLQEVLIKTHSNLHSLKdGSSIKSWLYQIANNTIIDFYRKKNRSEEL---PDD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1735107642 106 LFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGI 159
Cdd:PRK09637   81 LLFEDEEREENAKKELAPCLRPFIDALPEKYAEALRLTELEGLSQKEIAEKLGL 134
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
 9-179 2.34e-08

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 51.45  E-value: 2.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   9 MTDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANL--KLTSLNAYLYTSVRYQV 86
Cdd:PRK13919    8 LSDEALLALVARGEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFdpRRGSARAWLLALAHHAA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  87 FNVIRSGKVRADLF--NKLEELFSNNGGEELLSEKEINRL-LEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKT 163
Cdd:PRK13919   88 VDHVRRRAARPQPLepDEREPEAFDLPGPGLDEEGHLDRTrLGRALKALSPEERRVIEVLYYQGYTHREAAQLLGLPLGT 167

                         170
                  ....*....|....*.
gi 1735107642 164 VENQLTVALNRLRKTL 179
Cdd:PRK13919  168 LKTRARRALSRLKEVL 183
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
 14-179 2.50e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 51.26  E-value: 2.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  14 LIALIRENDLGAFERIYNKYWSKLYLSAYNIIrDRQVAEDVTQEVLVNLWmkRANLKLTSlNAYLYTSVRYQVFNVIRSG 93
Cdd:PRK12518    1 LILRCQRGDRQSFRQLYRRYQQKVRSTLYQLC-GRELLDDLVQEVFLRVW--KGLPKLRN-PAYFSTWLYRITWNVATDA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  94 -------KVRADLFNKLEELFSNNGGEELLsEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVEN 166
Cdd:PRK12518   77 rrqfaqrPSRIQDDSLNDQPSRPSDTPDLM-QLHYQDLVQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKS 155

                         170
                  ....*....|...
gi 1735107642 167 QLTVALNRLRKTL 179
Cdd:PRK12518  156 RLFYARRQLRKFL 168
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
 9-179 2.66e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 51.36  E-value: 2.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   9 MTDEDLIALIRENDLG---AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLN--AYLYTSVR 83
Cdd:PRK12514    1 TQPDDIEKLIVRVSLGdrdAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSpmTWLITIAR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  84 YQVFNVIRSGKVRADLFNKLEELFSNNGGEE----LLSE-KEINRLLEQGVAELPEKCRQIFImsrkEHLSTKEIAERLG 158
Cdd:PRK12514   81 NHAIDRLRARKAVAVDIDEAHDLADPSPGPEaeviAGDEgQRIDACLEELEKDRAAAVRRAYL----EGLSYKELAERHD 156

                         170       180
                  ....*....|....*....|.
gi 1735107642 159 IAPKTVENQLTVALNRLRKTL 179
Cdd:PRK12514  157 VPLNTMRTWLRRSLLKLRECL 177
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
 25-179 3.63e-08

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 50.40  E-value: 3.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  25 AFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKL-TSLNAYLYTSVRYQVFNVIRSGKVRADLFNK- 102
Cdd:TIGR02989   2 AFVRLLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDPgTNFVAWARGIARNKVLNYRRKLGRDRLVFDDd 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1735107642 103 -LEELFSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENqltvALNRLRKTL 179
Cdd:TIGR02989  82 lLEALAAEAEPTEAERLSDDRQALEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYK----ALQRIRVSL 155
PRK12520 PRK12520
RNA polymerase sigma factor; Provisional
 45-179 1.81e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237126 [Multi-domain]  Cd Length: 191  Bit Score: 48.96  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  45 IRDRQVAEDVTQE-VLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGK--VRADLFNK--------LEELFSNNGG- 112
Cdd:PRK12520   23 LRDPALAEDAVSEtLLAVLEHPERFAGQSSLKTYLVGILKHKIIDAIRSGRreVRLSLDDAdeqsdddlFDALFAADGHy 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735107642 113 ----------EELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK12520  103 reppsdwgdpDAALSRREFFEVLQACVDRLPPRTGRVFMMREWLELETEEICQELQITATNAWVLLYRARMRLRECL 179
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
12-180 6.47e-07

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 47.74  E-value: 6.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  12 EDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANL--KLTSLNAYLYTSVRYQVFNV 89
Cdd:PRK09646   18 DALLRRVARGDQDAFAELYDRTSSRVYGLVRRVLRDPGYSEETTQEVYLEVWRTASRFdpARGSALAWLLTLAHRRAVDR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  90 IRSGKVRADLfNKLEELFSNNGGEELLSEKEINRLLEQGV----AELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVE 165
Cdd:PRK09646   98 VRSEQAASQR-EVRYGARNVDPAFDQVAEEVEARLERERVrdclDALTDTQRESVTLAYYGGLTYREVAERLAVPLGTVK 176

                         170
                  ....*....|....*
gi 1735107642 166 NQLTVALNRLRKTLG 180
Cdd:PRK09646  177 TRMRDGLIRLRDCLG 191
PRK12517 PRK12517
RNA polymerase sigma factor; Provisional
 26-179 8.74e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183569 [Multi-domain]  Cd Length: 188  Bit Score: 46.99  E-value: 8.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  26 FERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWmkRAnlkLTSLN------AYLYTSVRYQvfNVIRSGKVRADL 99
Cdd:PRK12517   25 YEALVKALHADIYRYAYWLCKDKHIAEDLVQETFLRAW--RS---LDSLKdekaakAWLITILRRE--NARRFERKQFDL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 100 FNKLEELFSNNGGEELLSEKEiNRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK12517   98 VDIEDDSIEDDASHSSEEEME-QEWLRRQIAKLDPEYREPLLLQVIGGFSGEEIAEILDLNKNTVMTRLFRARNQLKEAL 176
PRK12523 PRK12523
RNA polymerase sigma factor; Reviewed
 48-172 4.72e-06

RNA polymerase sigma factor; Reviewed


Pssm-ID: 183572 [Multi-domain]  Cd Length: 172  Bit Score: 44.84  E-value: 4.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  48 RQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRsgkvRADLFNK-LEELFSNNGGEELLSE-------- 118
Cdd:PRK12523   34 RQRAEDLSQDTFVRLLGRPELPTPREPRAFLAAVAKGLMFDHFR----RAALEQAyLAELALVPEAEQPSPEeqhliled 109

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 119 -KEINRLLeqgvAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVAL 172
Cdd:PRK12523  110 lKAIDRLL----GKLSSKARAAFLYNRLDGMGHAEIAERLGVSVSRVRQYLAQGL 160
PRK09642 PRK09642
RNA polymerase sigma factor;
33-177 1.17e-05

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 43.55  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  33 YWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKLEE----LFS 108
Cdd:PRK09642    4 YRHYIFQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQFRGLKTWMARIATNHAIDYKRKKARENEELSLCKEteenIKS 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1735107642 109 NNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRK 177
Cdd:PRK09642   84 SHNIEDLLLTKEQKLLIAQKLRELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRARKWIKK 152
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
 27-176 1.39e-05

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 43.33  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  27 ERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKLEEL 106
Cdd:PRK09644    4 EEIYKMYINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYDNQKVKPWLFKVAYHTFIDFVRKEKKVSFVGTDEIEA 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 107 FSNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLR 176
Cdd:PRK09644   84 IQAESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLK 153
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
 125-180 2.40e-05

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 43.37  E-value: 2.40e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1735107642 125 LEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK07408  197 LQQALAQLEERTREVLEFVFLHDLTQKEAAERLGISPVTVSRRVKKGLDQLKKLLQ 252
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
 122-176 2.66e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 40.17  E-value: 2.66e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 122 NRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLR 176
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
PRK12539 PRK12539
RNA polymerase sigma factor SigF;
51-179 3.03e-05

RNA polymerase sigma factor SigF;


Pssm-ID: 237132 [Multi-domain]  Cd Length: 184  Bit Score: 42.79  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVLVNLWMKRANLKLTS-LNAYLYTSVRYQVFNVIRSGK-VRADL-FNKLEELFSNNGGEELLSEKEINRLLEq 127
Cdd:PRK12539   52 AEDLVQEALMAIHTRRHTYDPEQpLTPWVYAIARYKLIDHLRRTRaSLADVpIDDADELVAHDDHAAVESTLDLGRLLA- 130

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1735107642 128 gvaELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVEnqltVALNRLRKTL 179
Cdd:PRK12539  131 ---RLPEKMRLAIQAVKLEGLSVAEAATRSGMSESAVK----VSVHRGLKAL 175
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
 108-182 3.24e-05

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 43.14  E-value: 3.24e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 108 SNNGGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLGDF 182
Cdd:PRK06288  189 AALNPDEIAEREEIKRVIVEAIKTLPEREKKVLILYYYEDLTLKEIGKVLGVTESRISQLHTKAVLQLRAKLAEI 263
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
51-180 4.00e-05

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 42.26  E-value: 4.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVLVNLwmkranlkLTSLN----------AYLYTSVRYQVFNVIR-SGKVRADLFNKLEELFSNNGGEE---LL 116
Cdd:PRK09648   55 ADDVAQEVCLAV--------ITALPryrdqgrpflAFVYGIAAHKVADAHRaAGRDKAVPTEEVPERPSDDAGPEeraLR 126

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1735107642 117 SE--KEINRLLEqgvaELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK09648  127 SEssNRMRELLD----TLPEKQREILILRVVVGLSAEETAEAVGSTPGAVRVAQHRALARLRAEIE 188
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
9-179 5.58e-05

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 42.20  E-value: 5.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   9 MTDEDLIALIRENDLGAFERIYNKYWSKLY--LSAYNIIR-DRqvaEDVTQEVLVNLWmkRA-----NLKLTSLNAYLYT 80
Cdd:PRK08295    9 LEDEELVELARSGDKEALEYLIEKYKNFVRakARSYFLIGaDR---EDIVQEGMIGLY--KAirdydKDKLSSFKSFAEL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  81 SVRYQVFNVIRSG---------------KVRAD------LFNKLEELFSNNgGEELLSEKEINRLLEQGVAE-LPEKCRQ 138
Cdd:PRK08295   84 CITRQIITAIKTAnrqkhiplnsyvsldKPIYDeesdrtLLDVISEAKVTD-PEELIISKEELEDIEEKIEElLSELEKE 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1735107642 139 IFiMSRKEHLSTKEIAERLGIAPKTVENqltvALNRLRKTL 179
Cdd:PRK08295  163 VL-ELYLDGKSYQEIAEELNRHVKSIDN----ALQRVKRKL 198
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
 130-177 5.76e-05

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 39.33  E-value: 5.76e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1735107642 130 AELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRK 177
Cdd:pfam04545   3 ASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
 51-181 5.77e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 42.10  E-value: 5.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVLVNLWmKRANLKLTSLNA---YLYTSVRYQVFNVIRSGKVRA-----DLFNKLEELFSNNGGEEL-----LS 117
Cdd:PRK12526   65 ANELVQETMSNVW-RKAHLYNGDKGAattWVYTVMRNAAFDMLRKIKAKKeqnlgDDIWPIEQALAESQSESEefsdhLM 143

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1735107642 118 EKEINRLLEQgvaeLPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLGD 181
Cdd:PRK12526  144 DKQILSYIEK----LPEAQQTVVKGVYFQELSQEQLAQQLNVPLGTVKSRLRLALAKLKVQMGE 203
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
 41-180 6.74e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 41.40  E-value: 6.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  41 AYNIIRDRQVAEDVTQEVLVNLWMKRANLKL-TSLNAYLYTSVRYQVFNVIR-SGKVRADLFNKLEELFSNNGGEE-LLS 117
Cdd:PRK12547   23 AVSLSSKHDKAEDLVQDTLMKAWAKQDSFEMgTNLKAWLFTILRNEFYSQMRkRGREVQDSDGVFTARVAVHPAQYgSLD 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1735107642 118 EKEINRLLEQgvaeLPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK12547  103 LQDFKKALNL----LSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLK 161
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
 51-179 7.54e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 41.84  E-value: 7.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVL------VNLWMKRAnlkltSLNAYLYTSVRYQVFNVIR-SGKVR--------ADLFNKLEELFSNNGG--- 112
Cdd:PRK12532   33 AEDLVQETLlsaysaGDSFQGRA-----LVNSWLFAILKNKIIDALRqIGRQRkvftllddELLDEAFESHFSQNGHwtp 107

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735107642 113 ----------EELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPktveNQLTVALNRLRKTL 179
Cdd:PRK12532  108 egqpqhwntpEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGIST----SNYHTIMHRARESL 180
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
 40-180 8.00e-05

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 41.21  E-value: 8.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  40 SAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKLEELFS----NNGGEEL 115
Cdd:PRK07037   14 IAARIVGCRSRAEDVVQDAFVKLVEAPNQDAVKQPVAYLFRIVRNLAIDHYRRQALENKYHGDEEDGLDvpspEASPEAA 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 116 LSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK07037   94 LINRDTLRHVADALSELPARTRYAFEMYRLHGETQKDIARELGVSPTLVNFMIRDALVHCRKCLD 158
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 148-175 8.02e-05

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 39.05  E-value: 8.02e-05
                           10        20
                   ....*....|....*....|....*...
gi 1735107642  148 LSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:smart00421  19 LTNKEIAERLGISEKTVKTHLSNIMRKL 46
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
 36-179 9.76e-05

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 41.31  E-value: 9.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  36 KLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLNAYLYtSVRYQVF--NVIRSGKVRadlFNKLEELFSNNGGE 113
Cdd:PRK09647   40 RVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGTFEGWLH-RITTNLFldMVRRRARIR---MEALPEDYDRVPGD 115

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735107642 114 ELLSEK--EINRL---LEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK09647  116 EPNPEQiyHDARLdpdLQAALDSLPPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRQQLRAAL 186
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 113-175 9.92e-05

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 40.65  E-value: 9.92e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1735107642 113 EELLS--EKEINRLLEQGvaelpekcrqifimsrkehLSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:COG2197    67 RRLLTprEREVLRLLAEG-------------------LSNKEIAERLGISERTVKTHVSNILRKL 112
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
 22-179 1.31e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 40.81  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  22 DLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLNA--YLYTSVRYQVFNVIRSG--KVRA 97
Cdd:PRK12534   23 DRHAFEALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFDPSRARGltWLAMIARNKAIDHLRANapQRRN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  98 DLFNKLEELFSNngGEELLSEKE---INRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNR 174
Cdd:PRK12534  103 VALDDAGELRAA--DASPLERTErasTRRRIDHCLAELEPPRSELIRTAFFEGITYEELAARTDTPIGTVKSWIRRGLAK 180


                  ....*
gi 1735107642 175 LRKTL 179
Cdd:PRK12534  181 LKACL 185
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
 10-182 1.92e-04

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 40.46  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMK----RANLKLTSlnaYLYTSVRYQ 85
Cdd:PRK09643   13 SDAELLAAHVAGDRYAFGELFRRHHRRLWAVARRTSGTREDAADALQDAMLSAHRAagsfRGDAAVSS---WLHRIVVNA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  86 VFNVIRSGKVR-ADLFNKLEELFSNngGEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTV 164
Cdd:PRK09643   90 CLDRLRRAKARpTVPLDDVYPVAQL--ERDPTARVETALAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTV 167

                         170
                  ....*....|....*...
gi 1735107642 165 ENQLTVALNRLRKTLGDF 182
Cdd:PRK09643  168 KSRCARGRARLAELLGYL 185
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
 51-179 2.52e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 40.07  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVLVNLWMKRANLKLTS-LNAYLYTSVRYQVFNVIR--SGKVRADLFNKLEELFSNNGGEElLSEKEINRLLEQ 127
Cdd:PRK12512   53 AEDIVQEILLAVHLKRHTWDPGApFAPWLFAIARNKLIDALRrrGRRVFVDIDDFAETLPAEPATET-LPAGDVGRHLET 131

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1735107642 128 gvaeLPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVEnqltVALNRLRKTL 179
Cdd:PRK12512  132 ----LPPRQRDVVQSISVEGASIKETAAKLSMSEGAVR----VALHRGLAAL 175
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
 112-182 3.05e-04

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 40.37  E-value: 3.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735107642 112 GEELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLGDF 182
Cdd:PRK05911  186 GYDVVDKKEFSSILAEAILALEEKERKVMALYYYEELVLKEIGKILGVSESRVSQIHSKALLKLRATLSAF 256
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
 10-155 4.70e-04

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 39.40  E-value: 4.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  10 TDEDLIALIRENDLGAFERIYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANLKLTSLnayLYTSVRYQVFNV 89
Cdd:PRK11923    6 EDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRGDSA---FYTWLYRIAINT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  90 IRSGKVR-------ADLFNKLEELFSNNGG-------EELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAE 155
Cdd:PRK11923   83 AKNHLVSrgrrppdSDVSSEDAEFYDGDHAlkdiespERALLRDEIEGTVHRTIQQLPEDLRTALTLREFDGLSYEDIAS 162
PRK12545 PRK12545
RNA polymerase factor sigma-70;
45-181 5.74e-04

RNA polymerase factor sigma-70;


Pssm-ID: 183584 [Multi-domain]  Cd Length: 201  Bit Score: 39.17  E-value: 5.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  45 IRDRQVAEDVTQEVLVNLWMKRANLK-LTSLNAYLYTSVRYQVFNVIRSgKVRADLFNKLE-----------ELFSNNGG 112
Cdd:PRK12545   29 LRDADAAEDAVQEALAAAWSQAGRFAgQSAHKTWVFGILRNKLIDTLRA-RQRTVNLSALDaeldgealldrELFKDNGH 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642 113 -------------EELLSEKEINRLLEQGVAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTL 179
Cdd:PRK12545  108 waahakprpwpkpETILQQQQFWTLFETCLDHLPEQIGRVFMMREFLDFEIDDICTELTLTANHCSVLLYRARTRLRTCL 187


                  ..
gi 1735107642 180 GD 181
Cdd:PRK12545  188 SE 189
PRK12525 PRK12525
RNA polymerase sigma factor; Provisional
 51-174 6.93e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 139037 [Multi-domain]  Cd Length: 168  Bit Score: 38.77  E-value: 6.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  51 AEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRSGKVRADLFNKL----EELFSNNGGEELLSEK--EINRL 124
Cdd:PRK12525   36 AEDIASETFLQVLALPDPASIREPRALLTTIARRLMYEGWRRQDLERAYLQSLaeapEAVQPSPEEQWMVIETllAIDRL 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1735107642 125 LeqgvAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNR 174
Cdd:PRK12525  116 L----DGLSGKARAAFLMSQLEGLTYVEIGERLGVSLSRIHQYMVEAFKC 161
PRK12528 PRK12528
RNA polymerase sigma factor; Provisional
 49-174 1.41e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 171561 [Multi-domain]  Cd Length: 161  Bit Score: 37.90  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  49 QVAEDVTQEVLVNLWMKRANLKLTSLNAYLYTSVRYQVFNVIRsgkvRADLFNKLEELFSNNGGEELLSEK--------- 119
Cdd:PRK12528   29 QSAADLAQDTFVKVLVARETAQIIEPRAFLTTIAKRVLCNHYR----RQDLERAYLEALAQLPERVAPSEEeraiiletl 104

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1735107642 120 -EINRLLEQgvaeLPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNR 174
Cdd:PRK12528  105 vELDQLLDG----LPPLVKRAFLLAQVDGLGYGEIATELGISLATVKRYLNKAAMR 156
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
146-175 1.45e-03

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 38.20  E-value: 1.45e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1735107642 146 EHLSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:COG2771   141 EGLTLKEIARILGISERTVRTHLKRIYRKL 170
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 118-178 1.50e-03

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 36.09  E-value: 1.50e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735107642 118 EKEINRLLEQGvaelpekcrqifimsrkehLSTKEIAERLGIAPKTVENQLTvalNRLRKT 178
Cdd:COG5905    17 EREVLELLAEG-------------------LTNKEIARQLFISEKTVKNHVS---NILRKL 55
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
 41-180 1.90e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 37.51  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  41 AYNIIRDRQVAEDVTQEVLVNLWMKRANLKL-TSLNAYLYTSVRYQVFNVIRSGK-----VRADLFNKLEELFSNNGGee 114
Cdd:PRK12546   24 AISLTRNVAVADDLVQDTIVKAWTNFDKFQEgTNLRAWLFTILRNTFYSDRRKHKrevpdPEGVHAASLAVKPAHDGR-- 101

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1735107642 115 lLSEKEINRLLeqgvAELPEKCRQIFIMSRKEHLSTKEIAERLGIAPKTVENQLTVALNRLRKTLG 180
Cdd:PRK12546  102 -LAMSDFRAAF----AQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAELLQ 162
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
 29-92 2.90e-03

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 35.26  E-value: 2.90e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735107642  29 IYNKYWSKLYLSAYNIIRDRQVAEDVTQEVLVNLWMKRANL---KLTSLNAYLYTSVRYQVFNVIRS 92
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFdpeRGVSFSTWLYTIIRNAIIDYLRK 67
GerE pfam00196
Bacterial regulatory proteins, luxR family;
118-176 2.92e-03

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 34.87  E-value: 2.92e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1735107642 118 EKEINRLLEQGvaelpekcrqifimsrkehLSTKEIAERLGIAPKTVENQLTVALNRLR 176
Cdd:pfam00196   7 EREVLRWLAAG-------------------KSNKEIADELGISEKTVKVHRSNIMRKLN 46
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 148-165 4.67e-03

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 36.62  E-value: 4.67e-03
                          10
                  ....*....|....*...
gi 1735107642 148 LSTKEIAERLGIAPKTVE 165
Cdd:COG4566   153 LSNKQIARELGISPRTVE 170
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
 9-177 5.40e-03

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 36.07  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642   9 MTDEDLIALIRENDLGAFERIYNKYwSKLylsAYNIIRD-------RQVAEDVTQEVLVNLW--MKRANLKLTSLNAYLY 79
Cdd:PRK06811    3 INEDNFIKELKKKNEKALEFIVDTY-GNL---VKKIVHKvlgtvnySQLIEECVNDIFLSIWnnIDKFDEEKGSFKKWIA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735107642  80 TSVRYQVFNVIRS--GKVRADLFNKLEELFSNNGGEELLSEKEINRLLEQgVAELPEKCRQIFIMSRKEHLSTKEIAERL 157
Cdd:PRK06811   79 AISKYKAIDYKRKltKNNEIDSIDEFILISEESIENEIILKENKEEILKL-INDLEKLDREIFIRRYLLGEKIEEIAKKL 157

                         170       180
                  ....*....|....*....|
gi 1735107642 158 GIAPKTVENQLTVALNRLRK 177
Cdd:PRK06811  158 GLTRSAIDNRLSRGRKKLQK 177
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 148-175 5.63e-03

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 34.05  E-value: 5.63e-03
                          10        20
                  ....*....|....*....|....*...
gi 1735107642 148 LSTKEIAERLGIAPKTVENQLTVALNRL 175
Cdd:cd06170    16 KTNKEIADILGISEKTVKTHLRNIMRKL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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