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Conserved domains on  [gi|1725328767|gb|QEE83799|]
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L1 [Human papillomavirus type 7]

Protein Classification

major capsid protein L1( domain architecture ID 10010233)

major capsid protein L1 forms an icosahedral capsid with a 50 nm diameter; the capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-505 0e+00

major capsid L1 protein; Provisional


:

Pssm-ID: 222928  Cd Length: 503  Bit Score: 973.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767   1 MWQLNENQVYLPPpTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGD-VSVPKVSGHQYRVFRVRLPDPN 79
Cdd:PHA02778    3 LWLPSSGKLYLPP-TPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNkVTVPKVSGNQYRVFRVKLPDPN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767  80 KFGLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGC 159
Cdd:PHA02778   82 KFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGC 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 160 TPPIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEP 239
Cdd:PHA02778  162 TPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDP 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 240 YGNSLFFFLRREQMFVRHFFNRAGTTGDAVPNDLYITGSSNRAS-IAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHN 318
Cdd:PHA02778  242 YGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQtLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHN 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 319 NGICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLL 398
Cdd:PHA02778  322 NGICWNNQLFVTVVDNTRNTNFTISVKTDETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 399 DDWNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPK 478
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|....*..
gi 1725328767 479 FKSRKRPAPTsssssGSVTPKRKKTKR 505
Cdd:PHA02778  482 RRKRKSTSSS-----SSRSTKRRRRKR 503
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-505 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 973.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767   1 MWQLNENQVYLPPpTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGD-VSVPKVSGHQYRVFRVRLPDPN 79
Cdd:PHA02778    3 LWLPSSGKLYLPP-TPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNkVTVPKVSGNQYRVFRVKLPDPN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767  80 KFGLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGC 159
Cdd:PHA02778   82 KFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGC 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 160 TPPIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEP 239
Cdd:PHA02778  162 TPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDP 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 240 YGNSLFFFLRREQMFVRHFFNRAGTTGDAVPNDLYITGSSNRAS-IAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHN 318
Cdd:PHA02778  242 YGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQtLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHN 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 319 NGICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLL 398
Cdd:PHA02778  322 NGICWNNQLFVTVVDNTRNTNFTISVKTDETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 399 DDWNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPK 478
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|....*..
gi 1725328767 479 FKSRKRPAPTsssssGSVTPKRKKTKR 505
Cdd:PHA02778  482 RRKRKSTSSS-----SSRSTKRRRRKR 503
Late_protein_L1 pfam00500
L1 (late) protein;
2-502 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 841.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767   2 WQLNENQVYLPPpTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGDVSVPKVSGHQYRVFRVRLPDPNKF 81
Cdd:pfam00500   1 WLPSQQKLYLPP-QPVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKGRNDKVLVPKVSGNQYRVFRLKLPDPNRF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767  82 GLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGCTP 161
Cdd:pfam00500  80 ALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQGGDNRQNMAFDPKQTQMFIVGCTP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 162 PIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEPYG 241
Cdd:pfam00500 160 AIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAEDPYG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 242 NSLFFFLRREQMFVRHFFNRAGTTGDAVPNDLYITGSSN-RASIAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHNNG 320
Cdd:pfam00500 240 DSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKGAGEeQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQGHNNG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 321 ICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLLDD 400
Cdd:pfam00500 320 ICWNNQLFVTVVDNTRGTNFTISVKADENDETTYDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHTMNPSILED 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 401 WNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPkfK 480
Cdd:pfam00500 400 WNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSGLTQSS--S 477

                         490       500
                  ....*....|....*....|..
gi 1725328767 481 SRKRPAPTSSSSSGsvTPKRKK 502
Cdd:pfam00500 478 STKRKAPASVAVSR--SSKRKR 497
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-505 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 973.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767   1 MWQLNENQVYLPPpTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGD-VSVPKVSGHQYRVFRVRLPDPN 79
Cdd:PHA02778    3 LWLPSSGKLYLPP-TPVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDADKNkVTVPKVSGNQYRVFRVKLPDPN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767  80 KFGLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGC 159
Cdd:PHA02778   82 KFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGTDDRQNVSFDPKQTQLFIVGC 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 160 TPPIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEP 239
Cdd:PHA02778  162 TPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLKMANDP 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 240 YGNSLFFFLRREQMFVRHFFNRAGTTGDAVPNDLYITGSSNRAS-IAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHN 318
Cdd:PHA02778  242 YGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQtLGSSVYFPTPSGSLVSSDAQLFNRPYWLQRAQGHN 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 319 NGICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLL 398
Cdd:PHA02778  322 NGICWNNQLFVTVVDNTRNTNFTISVKTDETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAHLHTMNPSIL 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 399 DDWNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPK 478
Cdd:PHA02778  402 EDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLFQAGLRRRTR 481

                         490       500
                  ....*....|....*....|....*..
gi 1725328767 479 FKSRKRPAPTsssssGSVTPKRKKTKR 505
Cdd:PHA02778  482 RRKRKSTSSS-----SSRSTKRRRRKR 503
Late_protein_L1 pfam00500
L1 (late) protein;
2-502 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 841.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767   2 WQLNENQVYLPPpTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGDVSVPKVSGHQYRVFRVRLPDPNKF 81
Cdd:pfam00500   1 WLPSQQKLYLPP-QPVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKGRNDKVLVPKVSGNQYRVFRLKLPDPNRF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767  82 GLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGCTP 161
Cdd:pfam00500  80 ALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQGGDNRQNMAFDPKQTQMFIVGCTP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 162 PIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEPYG 241
Cdd:pfam00500 160 AIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAEDPYG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 242 NSLFFFLRREQMFVRHFFNRAGTTGDAVPNDLYITGSSN-RASIAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHNNG 320
Cdd:pfam00500 240 DSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKGAGEeQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQGHNNG 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 321 ICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLLDD 400
Cdd:pfam00500 320 ICWNNQLFVTVVDNTRGTNFTISVKADENDETTYDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHTMNPSILED 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1725328767 401 WNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPkfK 480
Cdd:pfam00500 400 WNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSGLTQSS--S 477

                         490       500
                  ....*....|....*....|..
gi 1725328767 481 SRKRPAPTSSSSSGsvTPKRKK 502
Cdd:pfam00500 478 STKRKAPASVAVSR--SSKRKR 497
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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