|
Name |
Accession |
Description |
Interval |
E-value |
| GrpE |
COG0576 |
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ... |
20-160 |
1.64e-50 |
|
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440341 [Multi-domain] Cd Length: 147 Bit Score: 158.39 E-value: 1.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 20 DALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALEsvpaeAIEQNEHLKSLVTGVE 99
Cdd:COG0576 2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALA-----AAEEDEDVKSLLEGVE 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 100 MTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:COG0576 77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVL 137
|
|
| PRK14141 |
PRK14141 |
heat shock protein GrpE; Provisional |
11-160 |
9.85e-50 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172630 Cd Length: 209 Bit Score: 158.68 E-value: 9.85e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAIEQNE- 89
Cdd:PRK14141 32 EDDPEPDPLEALKAENAELKDRMLRLAAEMENLRKRTQRDVADARAYGIAGFARDMLSVSDNLRRALDAIPAEARAAADa 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 90 HLKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14141 112 GLKALIEGVEMTERAMLNALERHGVKKLDPEGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGYTIGERVL 182
|
|
| GrpE |
cd00446 |
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ... |
27-160 |
6.04e-49 |
|
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.
Pssm-ID: 271355 [Multi-domain] Cd Length: 136 Bit Score: 154.20 E-value: 6.04e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 27 AQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEaieqnEHLKSLVTGVEMTEKSLL 106
Cdd:cd00446 1 KELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKE-----EELKNLLEGVEMTLKQLL 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1724176693 107 EAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:cd00446 76 KVLEKHGVEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVL 129
|
|
| GrpE |
pfam01025 |
GrpE; |
13-160 |
1.01e-45 |
|
GrpE;
Pssm-ID: 425996 [Multi-domain] Cd Length: 165 Bit Score: 146.98 E-value: 1.01e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 13 ENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPaeaieQNEHLK 92
Cdd:pfam01025 14 ESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSAP-----ENEDVK 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1724176693 93 SLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:pfam01025 89 SLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVL 156
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| GrpE |
COG0576 |
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ... |
20-160 |
1.64e-50 |
|
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440341 [Multi-domain] Cd Length: 147 Bit Score: 158.39 E-value: 1.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 20 DALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALEsvpaeAIEQNEHLKSLVTGVE 99
Cdd:COG0576 2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALA-----AAEEDEDVKSLLEGVE 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 100 MTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:COG0576 77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVL 137
|
|
| PRK14141 |
PRK14141 |
heat shock protein GrpE; Provisional |
11-160 |
9.85e-50 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172630 Cd Length: 209 Bit Score: 158.68 E-value: 9.85e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAIEQNE- 89
Cdd:PRK14141 32 EDDPEPDPLEALKAENAELKDRMLRLAAEMENLRKRTQRDVADARAYGIAGFARDMLSVSDNLRRALDAIPAEARAAADa 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 90 HLKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14141 112 GLKALIEGVEMTERAMLNALERHGVKKLDPEGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGYTIGERVL 182
|
|
| GrpE |
cd00446 |
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ... |
27-160 |
6.04e-49 |
|
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.
Pssm-ID: 271355 [Multi-domain] Cd Length: 136 Bit Score: 154.20 E-value: 6.04e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 27 AQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEaieqnEHLKSLVTGVEMTEKSLL 106
Cdd:cd00446 1 KELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKE-----EELKNLLEGVEMTLKQLL 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1724176693 107 EAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:cd00446 76 KVLEKHGVEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVL 129
|
|
| GrpE |
pfam01025 |
GrpE; |
13-160 |
1.01e-45 |
|
GrpE;
Pssm-ID: 425996 [Multi-domain] Cd Length: 165 Bit Score: 146.98 E-value: 1.01e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 13 ENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPaeaieQNEHLK 92
Cdd:pfam01025 14 ESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSAP-----ENEDVK 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1724176693 93 SLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:pfam01025 89 SLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVL 156
|
|
| PRK14155 |
PRK14155 |
heat shock protein GrpE; Provisional |
8-160 |
2.02e-43 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237627 [Multi-domain] Cd Length: 208 Bit Score: 142.80 E-value: 2.02e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 8 VPFPGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAieQ 87
Cdd:PRK14155 11 GPFEADDAAQEIEALKAEVAALKDQALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRATAASPKDS--A 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1724176693 88 NEHLKSLVTGVEMTEKSLLEAFEKNHIKRIDP-VGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14155 89 DPAVKNFIIGVEMTEKELLGAFERNGLKKIDPaKGDKFDPHLHQAMMEQPSTEVAAGGVLQVMQAGYELMGRLV 162
|
|
| PRK14140 |
PRK14140 |
heat shock protein GrpE; Provisional |
13-160 |
5.10e-34 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237622 [Multi-domain] Cd Length: 191 Bit Score: 118.18 E-value: 5.10e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 13 ENELDETDA----LRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPaeaieQN 88
Cdd:PRK14140 36 AELLDEEQAkiaeLEAKLDELEERYLRLQADFENYKRRIQKENEAAEKYRAQSLASDLLPALDNFERALQIEA-----DD 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1724176693 89 EHLKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14140 111 EQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVMQDEDEDFESNEVVEELQKGYKLKDRVI 182
|
|
| PRK14150 |
PRK14150 |
heat shock protein GrpE; Provisional |
13-160 |
9.63e-31 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184539 [Multi-domain] Cd Length: 193 Bit Score: 109.62 E-value: 9.63e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 13 ENELDETDAlraEVAQLKEQL-----------LRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVP 81
Cdd:PRK14150 33 EDELDEADA---RIAELEAQLaeaqaeerdsvLRARAEVENIRRRAEQDVEKAHKFALEKFANELLPVIDNLERALQAAD 109
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1724176693 82 AEaieqNEHLKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14150 110 KE----NEALKALIEGVELTLKSLLDTVAKFGVEVVGPVGEPFNPEVHQAISMQESEDHEPNTVMMVMQKGYTLNGRLL 184
|
|
| PRK14151 |
PRK14151 |
heat shock protein GrpE; Provisional |
2-160 |
1.42e-30 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172640 [Multi-domain] Cd Length: 176 Bit Score: 108.71 E-value: 1.42e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 2 NEDVGEVPFPGENELD-ETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESV 80
Cdd:PRK14151 11 APEAAQAEAAAGDDLTaRVQELEEQLAAAKDQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPVVDSLERGLELS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 81 PAEaieqNEHLKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14151 91 SAD----DEAIKPMREGVELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVEPNSVLKVFQKGYLLNGRLL 166
|
|
| PRK14139 |
PRK14139 |
heat shock protein GrpE; Provisional |
21-160 |
4.24e-30 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237621 [Multi-domain] Cd Length: 185 Bit Score: 107.75 E-value: 4.24e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 21 ALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALesvpaeAIEqNEHLKSLVTGVEM 100
Cdd:PRK14139 43 EAEAKAAELQDSFLRAKAETENVRRRAQEDVAKAHKFAIESFAESLLPVKDSLEAAL------ADE-SGDLEKLREGVEL 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 101 TEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEdPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14139 116 TLKQLTSAFEKGRVVEINPVGEKFDPHQHQAISMVP-AEQEPNTVVAVLQKGYTIADRVL 174
|
|
| PRK14161 |
PRK14161 |
heat shock protein GrpE; Provisional |
3-160 |
8.37e-29 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237630 [Multi-domain] Cd Length: 178 Bit Score: 104.29 E-value: 8.37e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 3 EDVGEVPFPGENEldETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPA 82
Cdd:PRK14161 14 NDIAEEIVETANP--EITALKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRALAHKPA 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1724176693 83 EAieqNEHLKSLVTGVEMTEKSLLEAFEKNHIKRIDP-VGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14161 92 NS---DVEVTNIIAGVQMTKDELDKVFHKHHIEEIKPeIGSMFDYNLHNAISQIEHPDHAPNSIITLMQSGYKIRDRLL 167
|
|
| PRK14147 |
PRK14147 |
heat shock protein GrpE; Provisional |
17-160 |
2.99e-26 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237625 [Multi-domain] Cd Length: 172 Bit Score: 97.71 E-value: 2.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 17 DETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAieqnehlKSLVT 96
Cdd:PRK14147 25 AEVESLRSEIALVKADALRERADLENQRKRIARDVEQARKFANEKLLGELLPVFDSLDAGLTAAGTEP-------SPLRD 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1724176693 97 GVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14147 98 GLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVAPGHVVQVFQKGYLLNERLL 161
|
|
| PRK14153 |
PRK14153 |
heat shock protein GrpE; Provisional |
18-160 |
4.59e-25 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184540 [Multi-domain] Cd Length: 194 Bit Score: 94.91 E-value: 4.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 18 ETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVpaeaiEQNEHLKSLVTG 97
Cdd:PRK14153 41 ETEKCREEIESLKEQLFRLAAEFDNFRKRTAREMEENRKFVLEQVLLDLLEVTDNFERALESA-----RTAEDMNSIVEG 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1724176693 98 VEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14153 116 IEMVSKQFFSILEKYGLERIECEGEEFDPHRHEAMMHVETSEVPDNTIVDVCKPGYALNSKVI 178
|
|
| PRK14162 |
PRK14162 |
heat shock protein GrpE; Provisional |
11-160 |
2.28e-21 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237631 [Multi-domain] Cd Length: 194 Bit Score: 85.66 E-value: 2.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALeSVPAEaieqNEH 90
Cdd:PRK14162 40 PVEDLEKEIADLKAKNKDLEDKYLRSQAEIQNMQNRYAKERAQLIKYESQSLAKDVLPAMDNLERAL-AVKAD----DEA 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1724176693 91 LKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAM--VEIEDPERaAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14162 115 AKQLKKGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAVqtVAAENDDQ-KDHVVQVLQKGYQYKDRTL 185
|
|
| PRK14148 |
PRK14148 |
heat shock protein GrpE; Provisional |
13-160 |
7.44e-21 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172637 [Multi-domain] Cd Length: 195 Bit Score: 84.42 E-value: 7.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 13 ENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRAL--ESVPAEAIEQNEh 90
Cdd:PRK14148 43 ERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFAKELLPVIDSIEQALkhEVKLEEAIAMKE- 121
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 91 lkslvtGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14148 122 ------GIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIV 185
|
|
| PRK14149 |
PRK14149 |
heat shock protein GrpE; Provisional |
12-160 |
4.32e-19 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184538 [Multi-domain] Cd Length: 191 Bit Score: 79.53 E-value: 4.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 12 GENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAIEQnehl 91
Cdd:PRK14149 38 SEKEGEIKEDFELKYKEMHEKYLRVHADFENVKKRLERDKSMALEYAYEKIALDLLPVIDALLGALKSAAEVDKES---- 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1724176693 92 kSLVTGVEMTEKSLLEAFEKNHIKRIDPVGErLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14149 114 -ALTKGLELTMEKLHEVLARHGIEGIECLEE-FDPNFHNAIMQVKSEEKENGKIVQVLQQGYKYKGRVL 180
|
|
| PRK14158 |
PRK14158 |
heat shock protein GrpE; Provisional |
21-160 |
1.30e-18 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172646 [Multi-domain] Cd Length: 194 Bit Score: 78.43 E-value: 1.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 21 ALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVpaeaieQNEHLKSLVTGVEM 100
Cdd:PRK14158 51 AKEAEAAANWDKYLRERADLENYRKRVQKEKEELLKYGNESLILEILPAVDNMERALDHA------DEESMSAIIEGIRM 124
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 101 TEKSLLEAFEKNHIKRID-PVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14158 125 TLSMLLSTLKKFGVTPVEaEKGTPFDPAYHQAMCQVESAEQEPNTVVAVFQKGYLLNERLL 185
|
|
| PRK14144 |
PRK14144 |
heat shock protein GrpE; Provisional |
11-160 |
1.70e-18 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184535 [Multi-domain] Cd Length: 199 Bit Score: 78.23 E-value: 1.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDALRAEVAQLK-EQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESvpaeAIEQNE 89
Cdd:PRK14144 45 PSYTALEEQLTLAEQKAHENwEKSVRALAELENVRRRMEREVANAHKYGVEKLISALLPVVDSLEQALQL----ADKNSD 120
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1724176693 90 hlKSLVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14144 121 --PSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQPAPGAPPNSVITVFQKGYKLSDRVI 189
|
|
| PRK14146 |
PRK14146 |
heat shock protein GrpE; Provisional |
18-153 |
8.43e-17 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 172635 [Multi-domain] Cd Length: 215 Bit Score: 74.00 E-value: 8.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 18 ETDALRAEVAQLKEQLLRAMADAENTRTRARKD----RDEAAKYAASGITKDLlsvaDNLRRaLESVPAeaieQNEHLKS 93
Cdd:PRK14146 62 ELDNAKKEIESLKDSWARERAEFQNFKRRSAQEfvsiRKEAVKSLVSGFLNPI----DNLER-VGATQN----QSEELKP 132
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 94 LVTGVEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGY 153
Cdd:PRK14146 133 FVEGVKMILKEFYSVLEKSNVIRFDPKGEPFDPMSMEALSSEEGDQYSEETVIDVYQAGY 192
|
|
| PRK10325 |
PRK10325 |
heat shock protein GrpE; Provisional |
30-158 |
1.85e-16 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 182379 [Multi-domain] Cd Length: 197 Bit Score: 72.78 E-value: 1.85e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 30 KEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESvpaeAIEQNEHLKSLVTGVEMTEKSLLEAF 109
Cdd:PRK10325 59 RDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEV----ADKANPDMSAMVEGIELTLKSMLDVV 134
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1724176693 110 EKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDR 158
Cdd:PRK10325 135 RKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGR 183
|
|
| PRK14160 |
PRK14160 |
heat shock protein GrpE; Provisional |
17-160 |
2.31e-16 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237629 [Multi-domain] Cd Length: 211 Bit Score: 72.87 E-value: 2.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 17 DETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALesvpaeAIEQNehLKSLVT 96
Cdd:PRK14160 68 EENKKLENELEALKDRLLRTVAEYDNYRKRTAKEKEGIYSDACEDVLKELLPVLDNLERAA------AVEGS--VEDLKK 139
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1724176693 97 GVEMTEKSLLEAFEKNHIKRIDPVGErLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14160 140 GIEMTVKQFKTSLEKLGVEEISTEGE-FDPNLHNAVMHVEDENYGENEIVEVFQKGYKRGDKVI 202
|
|
| PRK14154 |
PRK14154 |
heat shock protein GrpE; Provisional |
10-160 |
2.48e-15 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237626 [Multi-domain] Cd Length: 208 Bit Score: 69.84 E-value: 2.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 10 FPGENELD-ETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEaieqN 88
Cdd:PRK14154 51 FPSREKLEgQLTRMERKVDEYKTQYLRAQAEMDNLRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASE----D 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1724176693 89 EHLKSLVTGVEMTEKSLLEAFEKNHIKRIDP-VGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14154 127 PQVKSMRDGMSLTLDLLHNTLAKHGVQVINPnPGDPFDPALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVL 199
|
|
| PRK14156 |
PRK14156 |
heat shock protein GrpE; Provisional |
11-160 |
1.57e-10 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237628 [Multi-domain] Cd Length: 177 Bit Score: 56.38 E-value: 1.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDAlRAEvaQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALesvpaeaieQNEH 90
Cdd:PRK14156 31 PEKSELELANE-RAD--EFENKYLRAHAEMQNIQRRANEERQQLQRYRSQDLAKAILPSLDNLERAL---------AVEG 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1724176693 91 LKSLV-TGVEMTEKSLLEAFEKNHIKRIdpVGERLNPHYHEAMVEIE-DPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14156 99 LTDDVkKGLEMVQESLIQALKEEGVEEV--AVDSFDHNLHMAVQTLPaDDEHPADSIAQVFQKGYKLHERLL 168
|
|
| PRK14143 |
PRK14143 |
heat shock protein GrpE; Provisional |
18-160 |
1.58e-09 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237624 [Multi-domain] Cd Length: 238 Bit Score: 54.73 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 18 ETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVPAEAIEQNEHLKSLvTG 97
Cdd:PRK14143 75 ELESLKQELEELNSQYMRIAADFDNFRKRTSREQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAQALHRSY-QG 153
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1724176693 98 VEmteKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14143 154 LY---KQLVDVLKRLGVSPMRVVGQEFDPNLHEAVLREPSDEHPEDVVLEELQRGYHLGGRVL 213
|
|
| PRK14163 |
PRK14163 |
heat shock protein GrpE; Provisional |
18-160 |
1.57e-08 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184546 [Multi-domain] Cd Length: 214 Bit Score: 51.67 E-value: 1.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 18 ETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRAlesvpaeaieqNEHlKSLVTG 97
Cdd:PRK14163 48 QLDQVRTALGERTADLQRLQAEYQNYRRRVERDRVTVKEIAVANLLSELLPVLDDVGRA-----------REH-GELVGG 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1724176693 98 VEMTEKSLLEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14163 116 FKSVAESLETTVAKLGLQQFGKEGEPFDPTIHEALMHSYAPDVTETTCVAILQPGYRIGERTI 178
|
|
| PRK14157 |
PRK14157 |
heat shock protein GrpE; Provisional |
3-160 |
4.09e-08 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 184543 [Multi-domain] Cd Length: 227 Bit Score: 50.73 E-value: 4.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 3 EDVGEVPFPGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRALESVpa 82
Cdd:PRK14157 70 EKTGEAQSDSDDTLTPLGQAKKEAAEYLEALQRERAEFINYRNRTQKEQDRFRQHGIIDVLTALLPALDDIDRIREHS-- 147
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1724176693 83 eaiEQNEHLKSLVTGVEmteksllEAFEKNHIKRIDPVGERLNPHYHEAMVEIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14157 148 ---EMDDSFKAVAAKID-------KAFEKFGVEKFGEKGEDFDPTKHDAILHKPDPDAEKETVDTVVEAGYRIGDRVI 215
|
|
| PRK14142 |
PRK14142 |
heat shock protein GrpE; Provisional |
11-160 |
4.21e-08 |
|
heat shock protein GrpE; Provisional
Pssm-ID: 237623 Cd Length: 223 Bit Score: 50.38 E-value: 4.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724176693 11 PGENELDETDALRAEVAQLKEQLLRAMADAENTRTRARKDRDEAAKYAASGITKDLLSVADNLRRA-----LESVPAEAI 85
Cdd:PRK14142 34 PGGTAAADAAHTEDKVAELTADLQRVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERArkhgdLESGPLKSV 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1724176693 86 EqnEHLKSLVTGVEMTekslleAFEKNhikridpvGERLNPHYHEAMV-EIEDPERAAGTVSQVFEPGYVLHDRLL 160
Cdd:PRK14142 114 A--DKLDSALTGLGLV------AFGAE--------GEDFDPVLHEAVQhEGDGGQGSKPVIGTVMRQGYQLGEQVL 173
|
|
|