EAL domain-containing protein, partial [Lujinxingia vulgaris]
List of domain hits
Name | Accession | Description | Interval | E-value | ||
EAL super family | cl29561 | EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
108-158 | 2.80e-14 | ||
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria. The actual alignment was detected with superfamily member cd01948: Pssm-ID: 453023 [Multi-domain] Cd Length: 240 Bit Score: 67.96 E-value: 2.80e-14
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REC super family | cl19078 | phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response ... |
28-87 | 4.91e-03 | ||
phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs); Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays. The actual alignment was detected with superfamily member cd17530: Pssm-ID: 473134 [Multi-domain] Cd Length: 123 Bit Score: 35.11 E-value: 4.91e-03
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Name | Accession | Description | Interval | E-value | ||
EAL | cd01948 | EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
108-158 | 2.80e-14 | ||
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria. Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 67.96 E-value: 2.80e-14
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COG5001 | COG5001 | Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
108-158 | 2.10e-13 | ||
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms]; Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 66.72 E-value: 2.10e-13
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EAL | pfam00563 | EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
108-169 | 1.35e-12 | ||
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site. Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 63.11 E-value: 1.35e-12
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EAL | smart00052 | Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
107-158 | 6.29e-11 | ||
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria. Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 58.77 E-value: 6.29e-11
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PRK11359 | PRK11359 | cyclic-di-GMP phosphodiesterase; Provisional |
106-158 | 4.61e-06 | ||
cyclic-di-GMP phosphodiesterase; Provisional Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 45.53 E-value: 4.61e-06
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REC_RocR | cd17530 | phosphoacceptor receiver (REC) domain of response regulator RocR; The response regulator RocR ... |
28-87 | 4.91e-03 | ||
phosphoacceptor receiver (REC) domain of response regulator RocR; The response regulator RocR from some pathogens contains an N-terminal phosphoreceiver (REC) domain and a C-terminal EAL domain that possesses c-di-GMP specific phosphodiesterase activity. The RocR REC domain is phosphorylated and modulates its EAL domain enzymatic activity, regulating the local level of c-di-GMP. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381086 [Multi-domain] Cd Length: 123 Bit Score: 35.11 E-value: 4.91e-03
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Name | Accession | Description | Interval | E-value | ||
EAL | cd01948 | EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
108-158 | 2.80e-14 | ||
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria. Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 67.96 E-value: 2.80e-14
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COG5001 | COG5001 | Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
108-158 | 2.10e-13 | ||
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms]; Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 66.72 E-value: 2.10e-13
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EAL | pfam00563 | EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
108-169 | 1.35e-12 | ||
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site. Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 63.11 E-value: 1.35e-12
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EAL | COG2200 | EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ... |
106-158 | 1.03e-11 | ||
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms]; Pssm-ID: 441802 [Multi-domain] Cd Length: 576 Bit Score: 62.11 E-value: 1.03e-11
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EAL | smart00052 | Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
107-158 | 6.29e-11 | ||
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria. Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 58.77 E-value: 6.29e-11
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YjcC | COG4943 | Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ... |
105-158 | 9.58e-09 | ||
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms]; Pssm-ID: 443970 [Multi-domain] Cd Length: 528 Bit Score: 53.38 E-value: 9.58e-09
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PRK11359 | PRK11359 | cyclic-di-GMP phosphodiesterase; Provisional |
106-158 | 4.61e-06 | ||
cyclic-di-GMP phosphodiesterase; Provisional Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 45.53 E-value: 4.61e-06
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PRK10060 | PRK10060 | cyclic di-GMP phosphodiesterase; |
108-158 | 2.49e-05 | ||
cyclic di-GMP phosphodiesterase; Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 43.52 E-value: 2.49e-05
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PRK11829 | PRK11829 | biofilm formation regulator HmsP; Provisional |
91-158 | 3.62e-04 | ||
biofilm formation regulator HmsP; Provisional Pssm-ID: 183329 [Multi-domain] Cd Length: 660 Bit Score: 39.93 E-value: 3.62e-04
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PRK10551 | PRK10551 | cyclic di-GMP phosphodiesterase; |
118-158 | 9.51e-04 | ||
cyclic di-GMP phosphodiesterase; Pssm-ID: 182541 [Multi-domain] Cd Length: 518 Bit Score: 38.82 E-value: 9.51e-04
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PRK13561 | PRK13561 | putative diguanylate cyclase; Provisional |
108-145 | 3.77e-03 | ||
putative diguanylate cyclase; Provisional Pssm-ID: 184143 [Multi-domain] Cd Length: 651 Bit Score: 37.00 E-value: 3.77e-03
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REC_RocR | cd17530 | phosphoacceptor receiver (REC) domain of response regulator RocR; The response regulator RocR ... |
28-87 | 4.91e-03 | ||
phosphoacceptor receiver (REC) domain of response regulator RocR; The response regulator RocR from some pathogens contains an N-terminal phosphoreceiver (REC) domain and a C-terminal EAL domain that possesses c-di-GMP specific phosphodiesterase activity. The RocR REC domain is phosphorylated and modulates its EAL domain enzymatic activity, regulating the local level of c-di-GMP. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Pssm-ID: 381086 [Multi-domain] Cd Length: 123 Bit Score: 35.11 E-value: 4.91e-03
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Blast search parameters | ||||
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