NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1724161670|ref|WP_146972576|]
View 

GFA family protein [Lujinxingia vulgaris]

Protein Classification

GFA family protein( domain architecture ID 10007990)

GFA family protein similar to bacterial glutathione-dependent formaldehyde-activating enzyme, which catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione, and to eukaryotic centromere protein V, which plays a role in the distribution of pericentromeric heterochromatin in interphase nuclei

CATH:  2.170.150.70
Gene Ontology:  GO:0016846|GO:0046872

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
10-145 1.21e-14

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443005  Cd Length: 132  Bit Score: 66.58  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670  10 SCTCGSVTLKLTGKAIACLSCYCDDCQagarqietlpgagkvtRDGGG--TEYVMYRNDRMEVGQGAPHLTDYklRDDSA 87
Cdd:COG3791     7 SCLCGAVRFEVDGPPLRVGACHCSICR----------------KATGSafAAVALVPADAFRLTSGEDALTTY--RSSAT 68

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1724161670  88 TSRMVASCCNSPMYLNFSDSRHWVSLYRARFEDDAP-PLDVRMCTKFASEEVVIPDDVP 145
Cdd:COG3791    69 AERHFCPTCGSPLFYRRRGGPGLVAVNAGLLDDPDGlPPTAHIFTSSKPPWVEIPDGLP 127
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
10-145 1.21e-14

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 66.58  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670  10 SCTCGSVTLKLTGKAIACLSCYCDDCQagarqietlpgagkvtRDGGG--TEYVMYRNDRMEVGQGAPHLTDYklRDDSA 87
Cdd:COG3791     7 SCLCGAVRFEVDGPPLRVGACHCSICR----------------KATGSafAAVALVPADAFRLTSGEDALTTY--RSSAT 68

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1724161670  88 TSRMVASCCNSPMYLNFSDSRHWVSLYRARFEDDAP-PLDVRMCTKFASEEVVIPDDVP 145
Cdd:COG3791    69 AERHFCPTCGSPLFYRRRGGPGLVAVNAGLLDDPDGlPPTAHIFTSSKPPWVEIPDGLP 127
DUF6151 pfam19648
Family of unknown function (DUF6151); This family of proteins is functionally uncharacterized. ...
 4-160 1.42e-04

Family of unknown function (DUF6151); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 185 and 201 amino acids in length.


Pssm-ID: 437480  Cd Length: 188  Bit Score: 40.46  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670   4 SDVNQVSCTCGSVT--LKLTGKAIACLSCYCDDCQAGARQietLPGAGKVTRDGGGTEYVMYRNDRMEVGQGAPHLTDYK 81
Cdd:pfam19648   2 SKVVPLACSCGAVKgeLNVVPGDFFHVACLCCDCQAFAAK---LGREDFVLDSSGGSELFQTYPAYFTITEGAEHIRALQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670  82 LRdDSATSRMVASCCNSPMyLNFSDSRH----WVSLYRARFEDDAP------PLDVRMCTKFASEEvvIPDDVPSVSSYS 151
Cdd:pfam19648  79 LK-PKGLFRWYTACCNTPL-ANTMKSAHvpfvGLSVKLMQFDSAADksaaigPVTLRAFGKHARGP--MPADAHATFPKS 154

                         170
                  ....*....|....
gi 1724161670 152 -----LKFMGKLLM 160
Cdd:pfam19648 155 flpkiLKFMGKGLL 168
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
10-145 1.21e-14

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 66.58  E-value: 1.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670  10 SCTCGSVTLKLTGKAIACLSCYCDDCQagarqietlpgagkvtRDGGG--TEYVMYRNDRMEVGQGAPHLTDYklRDDSA 87
Cdd:COG3791     7 SCLCGAVRFEVDGPPLRVGACHCSICR----------------KATGSafAAVALVPADAFRLTSGEDALTTY--RSSAT 68

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1724161670  88 TSRMVASCCNSPMYLNFSDSRHWVSLYRARFEDDAP-PLDVRMCTKFASEEVVIPDDVP 145
Cdd:COG3791    69 AERHFCPTCGSPLFYRRRGGPGLVAVNAGLLDDPDGlPPTAHIFTSSKPPWVEIPDGLP 127
DUF6151 pfam19648
Family of unknown function (DUF6151); This family of proteins is functionally uncharacterized. ...
 4-160 1.42e-04

Family of unknown function (DUF6151); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 185 and 201 amino acids in length.


Pssm-ID: 437480  Cd Length: 188  Bit Score: 40.46  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670   4 SDVNQVSCTCGSVT--LKLTGKAIACLSCYCDDCQAGARQietLPGAGKVTRDGGGTEYVMYRNDRMEVGQGAPHLTDYK 81
Cdd:pfam19648   2 SKVVPLACSCGAVKgeLNVVPGDFFHVACLCCDCQAFAAK---LGREDFVLDSSGGSELFQTYPAYFTITEGAEHIRALQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1724161670  82 LRdDSATSRMVASCCNSPMyLNFSDSRH----WVSLYRARFEDDAP------PLDVRMCTKFASEEvvIPDDVPSVSSYS 151
Cdd:pfam19648  79 LK-PKGLFRWYTACCNTPL-ANTMKSAHvpfvGLSVKLMQFDSAADksaaigPVTLRAFGKHARGP--MPADAHATFPKS 154

                         170
                  ....*....|....
gi 1724161670 152 -----LKFMGKLLM 160
Cdd:pfam19648 155 flpkiLKFMGKGLL 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH