|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
2-435 |
0e+00 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 711.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 2 VLLYTPKQKTKNVQTITADILDLDYQGLGVAKINGKTWFIENALPHEKVECRILEDKRQYGHAIVKKWRVKSPERLEPKC 81
Cdd:PRK13168 1 AQFYSPKRRVTTRQIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 82 AHFMRCGGCQGQHIPIEMQRKAKESALFKRLSKLQS-EPISFQPMICGDAWAYRRRVRLSLWFNPSTKQIEMGFRQKNTN 160
Cdd:PRK13168 81 PHFGVCGGCQLQHLSIDAQIASKQRALEDLLKHLAGvEPEEVLPPIAGPPWGYRRRARLSVRYVPKKGQLLVGFREKNSS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 161 DLIPVQSCEVAEPAINYLLPKLTALLEKFSAPKQLGHIELVAADNGVAMLLRYTKNLAEIDRTLLLKFAEQEKLMLFLQS 240
Cdd:PRK13168 161 DIVDIDQCPVLVPPLSALLPPLRALLSSLSAKRRLGHVELAQGDNGTALVLRHLEPLSEADRAKLRAFAEQHGLQLYLQP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 241 DKGIEQIYGDAP-----YYQFSDGIKLHFDIRDFIQVNSALNEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVK 315
Cdd:PRK13168 241 KGPDLVHLLGPAdaqlsYYLPEFGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQPGDRVLDLFCGLGNFTLPLARQAA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 316 SAVGIEGVFEMVQKAAQNAERNQIKNIEFFQADLDQSFVEQPWANQSFNKILLDPPRSGAAFALNALCELKAEKILYVSC 395
Cdd:PRK13168 321 EVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDQPWALGGFDKVLLDPPRAGAAEVMQALAKLGPKRIVYVSC 400
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1723812 396 NPATLVRDAEILCNFGYKIEKSAVIDMFPHTGHLESITLF 435
Cdd:PRK13168 401 NPATLARDAGVLVEAGYRLKRAGMLDMFPHTGHVESMALF 440
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
24-430 |
0e+00 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 662.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 24 LDYQGLGVAKINGKTWFIENALPHEKVECRILEDKRQYGHAIVKKWRVKSPERLEPKCAHFMRCGGCQGQHIPIEMQRKA 103
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 104 KE---SALFKRLSKLQSEPISFQPMICGDAWAYRRRVRLSLWFNPSTkQIEMGFRQKNTNDLIPVQSCEVAEPAINYLLP 180
Cdd:TIGR00479 81 KQqqvIALLERIGKFVSEPIEDVPTIGDDPWGYRNKARLSLGRSPSG-QLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 181 KLTALLEKFSAPKQLGHIELVAADNGVAMLLRYTKNLAEIDRTLLLKFAEQEKLMLFLQSD------------------- 241
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDspdvksicqninpektnvi 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 242 --KGIEQIYGDAPYYQFSDGIKLHFDIRDFIQVNSALNEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVG 319
Cdd:TIGR00479 240 fgEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 320 IEGVFEMVQKAAQNAERNQIKNIEFFQADLDQSFVEQPWANQSFNKILLDPPRSG-AAFALNALCELKAEKILYVSCNPA 398
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGcAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 1723812 399 TLVRDAEILCNFGYKIEKSAVIDMFPHTGHLE 430
Cdd:TIGR00479 400 TLARDLEALCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
15-436 |
4.33e-149 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 428.44 E-value: 4.33e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 15 QTITADILDLDYQGLGVAKINGKTWFIENALPHEKVECRILEDKRQYGHAIVKKWRVKSPERLEPKCAHFMRCGGCQGQH 94
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 95 IPIEMQRKAKESALFKRLSKLQSEP-ISFQPMI-CGDAWAYRRRVRLSlwFNPSTKQIEMGFRQKNTNDLIPVQSCEVAE 172
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIGGLPeVEVEPIIgSPEPWGYRNRARLS--VRRTDGRLRLGFYARGSHELVDIDECPLLD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 173 PAINYLLPKLTALLEKFSAPK-QLGHIELVAADngvamllrytknlaeidrtlllkfaeqeklmlflqsdkgieqiygDA 251
Cdd:COG2265 159 PALNALLPALRELLAELGARRgELRHLVVRAGR---------------------------------------------DY 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 252 PYYQFsDGIKLHFDIRDFIQVNSALNEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAA 331
Cdd:COG2265 194 LTERL-GGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDAR 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 332 QNAERNQIKNIEFFQADLDQSFVEQPWaNQSFNKILLDPPRSGAAF-ALNALCELKAEKILYVSCNPATLVRDAEILCNF 410
Cdd:COG2265 273 ENARLNGLKNVEFVAGDLEEVLPELLW-GGRPDVVVLDPPRAGAGPeVLEALAALGPRRIVYVSCNPATLARDLALLVEG 351
|
410 420
....*....|....*....|....*.
gi 1723812 411 GYKIEKSAVIDMFPHTGHLESITLFT 436
Cdd:COG2265 352 GYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
87-438 |
5.65e-36 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 135.73 E-value: 5.65e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 87 CGGCQGQHIPIEMQRKAKESALFKRLSKLQS-EPISFQpmicGDAWAYRRRVRLSLWFNPSTKQIEMgFRQKnTNDLIPV 165
Cdd:PRK05031 1 MTPECLPPEQYEAQLAEKVARLKELFAPFSApEPEVFR----SPPSHYRMRAEFRIWHEGDDLYYAM-FDQQ-TKQRIRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 166 QSCEVAEPAINYLLPKLTALLEKFSAPKQ-LGHIELVAADNGVAML-LRYTKNLAEIDRTLLLKFAEQ------------ 231
Cdd:PRK05031 75 DQFPIASELINALMPALLAALRANPVLRHkLFQVDFLSTLSGEILVsLLYHKKLDEEWEQAAKALRDAlfnvhligrsrk 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 232 EKLMLflQSDKGIE--QIYGDAPYYQFSDGiklhfdirDFIQVNSALNEPMVNTALDWLELSQQDcVLDLFCGMGNFTLP 309
Cdd:PRK05031 155 QKIVL--DQDYVDErlPVAGREFIYRQVEN--------SFTQPNAAVNEKMLEWALDATKGSKGD-LLELYCGNGNFTLA 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 310 LAKRV---------KSAVgiegvfemvqKAAQ-NAERNQIKNI--------EFFQA-------------DLDqSFveqpw 358
Cdd:PRK05031 224 LARNFrrvlateisKPSV----------AAAQyNIAANGIDNVqiirmsaeEFTQAmngvrefnrlkgiDLK-SY----- 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 359 anqSFNKILLDPPRSGaafaLN-ALCEL--KAEKILYVSCNPATLVRDAEILCNfGYKIEKSAVIDMFPHTGHLESITLF 435
Cdd:PRK05031 288 ---NFSTIFVDPPRAG----LDdETLKLvqAYERILYISCNPETLCENLETLSQ-THKVERFALFDQFPYTHHMECGVLL 359
|
...
gi 1723812 436 TTK 438
Cdd:PRK05031 360 EKK 362
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
133-438 |
3.44e-28 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 114.07 E-value: 3.44e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 133 YRRRVRLSLWFNPSTKQIEMgFRQKnTNDLIPVQSCEVAEPAINYLLPKLTALLEKFSAPK-QLGHIELVAADNGVAML- 210
Cdd:pfam05958 35 YRMRAEFRIWHEGDDLYYAM-FDQQ-TKSRIRVDQFPAASELINELMPALIAALRQDPALRhKLFQVDFLTTLSGEALVs 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 211 LRYTKNLAEIDRTLLLKFAEQEKLMLF--------------LQSDKGIE--QIYGDAPYYQFSDGiklhfdirDFIQVNS 274
Cdd:pfam05958 113 LLYHKQLDDEWRQAAEALRDALRAQGLdvnligrarkqkivLDQDYVDEtlPVAGREFIYRQVEN--------SFTQPNA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 275 ALNEPMVNTALDWLELSQQDcVLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNQIKNI--------EFFQ 346
Cdd:pfam05958 185 AVNIKMLEWACDVTQGSKGD-LLELYCGNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVqiirmsaeEFTQ 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 347 A-------------DLDqSFveqpwanqSFNKILLDPPRSGAAfalNALCEL--KAEKILYVSCNPATLVRDAEILCNfG 411
Cdd:pfam05958 264 AmngvrefnrlkgiDLK-SY--------NCSTIFVDPPRAGLD---PETLKLvqAYPRILYISCNPETLCANLEQLSK-T 330
|
330 340
....*....|....*....|....*..
gi 1723812 412 YKIEKSAVIDMFPHTGHLESITLFTTK 438
Cdd:pfam05958 331 HRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
259-434 |
5.65e-24 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 101.48 E-value: 5.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 259 GIKLHFDIRDFIQVNSALNEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNQ 338
Cdd:PRK03522 140 GVPLFIRPQSFFQTNPAVAAQLYATARDWVRELPPRSMWDLFCGVGGFGLHCATPGMQLTGIEISAEAIACAKQSAAELG 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 339 IKNIEFFQADLDQSFVEQPWANQSfnkILLDPPRSGAAFALNA-LCELKAEKILYVSCNPATLVRDAEILCnfGYKIEKS 417
Cdd:PRK03522 220 LTNVQFQALDSTQFATAQGEVPDL---VLVNPPRRGIGKELCDyLSQMAPRFILYSSCNAQTMAKDLAHLP--GYRIERV 294
|
170
....*....|....*..
gi 1723812 418 AVIDMFPHTGHLESITL 434
Cdd:PRK03522 295 QLFDMFPHTAHYEVLTL 311
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
81-436 |
2.20e-23 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 101.07 E-value: 2.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 81 CAHFM--RCGGCQGQHIPIEMQRKAKESALFKRLSKLQSEpISFQPMICGDAWAYRRRVRLSLwfNPSTKQIEMGFrQKN 158
Cdd:TIGR02085 2 CAFYIqgRCRSCQWLAQPYSEQLTNKQQHLKELLAPNATV-VQWLAPVTSAEQAFRNKAKMVV--SGSVERPILGI-LHR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 159 TNDLIPVQSCEVAEPAINYLLPKLT-----ALLEKFSAPKQLGHIELV----AADNGVAML---LRYTKNLAEIDR---T 223
Cdd:TIGR02085 78 DGTPLDLCDCPLYPQSFQPVFAYLKnfiarAGLTPYNVAKKKGELKFIllteSENSGQLMLrfvLRSETKLAQIRRalpW 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 224 LLLKFAEQEKLMLFLQSD-----KGIEQIY---GDAPYYQFSDgIKLHFDIRDFIQVNSALNEPMVNTALDWLELSQQDC 295
Cdd:TIGR02085 158 LIEQLPQLEVISVNIQPVhmailEGEEEIFlteQQALPERFND-VPLVIRPQSFFQTNPKVAAQLYATARQWVREIPVTQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNQIKNIEFfqADLDQSFVEQPWANQSfNKILLDPPRSGA 375
Cdd:TIGR02085 237 MWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSF--AALDSAKFATAQMSAP-ELVLVNPPRRGI 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1723812 376 AFALNALCELKAEK-ILYVSCNPATLVRDAEILCnfGYKIEKSAVIDMFPHTGHLESITLFT 436
Cdd:TIGR02085 314 GKELCDYLSQMAPKfILYSSCNAQTMAKDIAELS--GYQIERVQLFDMFPHTSHYEVLTLLV 373
|
|
| TRAM |
pfam01938 |
TRAM domain; This small domain has no known function. However it may perform a nucleic acid ... |
10-67 |
6.24e-13 |
|
TRAM domain; This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation).
Pssm-ID: 396497 [Multi-domain] Cd Length: 59 Bit Score: 63.39 E-value: 6.24e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1723812 10 KTKNVQTITADILDLDYQGLGVAKI-NGKTWFIENALPHEKVECRILEDKRQYGHAIVK 67
Cdd:pfam01938 1 RRYVGQTQEVLVEGLSSNGEGIGRTdNGKVVFVPGALPGEFVEVKITKVKRNYLRGELL 59
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
296-395 |
2.53e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 63.22 E-value: 2.53e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKR-VKSAVGIEGVFEMVQKAAQNAERNQIKNIEFFQADLDQsfvEQPWANQSFNKILLDPP--- 371
Cdd:cd02440 2 VLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEE---LPPEADESFDVIISDPPlhh 78
|
90 100
....*....|....*....|....*.
gi 1723812 372 --RSGAAFALNALCELKAEKILYVSC 395
Cdd:cd02440 79 lvEDLARFLEEARRLLKPGGVLVLTL 104
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
284-368 |
4.84e-11 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 60.39 E-value: 4.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 284 ALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNQIkNIEFFQADLDQsfveQPWANQSF 363
Cdd:COG2226 14 LLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAED----LPFPDGSF 88
|
....*
gi 1723812 364 NKILL 368
Cdd:COG2226 89 DLVIS 93
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
279-407 |
3.76e-10 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 59.16 E-value: 3.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 279 PMVNTALDWLE-LSQQDCVLDLFCGMGNFTLPLAKRVKSAV-GIEGVFEMVQKAAQNAERNQIKNIEFFQADLDQSfveQ 356
Cdd:COG0500 12 PGLAALLALLErLPKGGRVLDLGCGTGRNLLALAARFGGRViGIDLSPEAIALARARAAKAGLGNVEFLVADLAEL---D 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1723812 357 PWANQSFNKIL-------LDPPRSGAAFA-LNALceLKAEKILYVSCNPATLVRDAEIL 407
Cdd:COG0500 89 PLPAESFDLVVafgvlhhLPPEEREALLReLARA--LKPGGVLLLSASDAAAALSLARL 145
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
296-378 |
4.31e-10 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 56.42 E-value: 4.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKSAV-GIEGVFEMVQKAAQNAERNQIkNIEFFQADLDqsfvEQPWANQSFNKIL------- 367
Cdd:pfam13649 1 VLDLGCGTGRLTLALARRGGARVtGVDLSPEMLERARERAAEAGL-NVEFVQGDAE----DLPFPDGSFDLVVssgvlhh 75
|
90
....*....|.
gi 1723812 368 LDPPRSGAAFA 378
Cdd:pfam13649 76 LPDPDLEAALR 86
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
296-391 |
1.39e-09 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 56.27 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKS---AVGIEGVFEMVQKAAQNAERNQIKNIEFFQADLDQsfVEQPWANQSFNKILLDppR 372
Cdd:pfam13847 7 VLDLGCGTGHLSFELAEELGPnaeVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEE--LPELLEDDKFDVVISN--C 82
|
90
....*....|....*....
gi 1723812 373 SGAAFALNALCELKAEKIL 391
Cdd:pfam13847 83 VLNHIPDPDKVLQEILRVL 101
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
296-363 |
1.53e-07 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 49.05 E-value: 1.53e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKSA--VGIEGVFEMVQKAAQNAErnqikNIEFFQADLDQSFVEQP----WANQSF 363
Cdd:COG4106 5 VLDLGCGTGRLTALLAERFPGArvTGVDLSPEMLARARARLP-----NVRFVVADLRDLDPPEPfdlvVSNAAL 73
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
296-351 |
1.59e-07 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 50.02 E-value: 1.59e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNqikNIEFFQADLDQ 351
Cdd:COG2227 28 VLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAEL---NVDFVQGDLED 80
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
296-381 |
1.13e-06 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 48.36 E-value: 1.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKRVKSA--VGIEGVFEMVQKAAQNAERNQIKNIEFFQADLDqsfveQPWANQSFNKILLDPP-R 372
Cdd:pfam05175 35 VLDLGCGAGVLGAALAKESPDAelTMVDINARALESARENLAANGLENGEVVASDVY-----SGVEDGKFDLIISNPPfH 109
|
....*....
gi 1723812 373 SGAAFALNA 381
Cdd:pfam05175 110 AGLATTYNV 118
|
|
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
270-348 |
6.60e-06 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 46.59 E-value: 6.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 270 IQVNSALNEP-MVNTALDWLELSQQDCVLDLFCGMGNFTLPLA---KRVKSAVGIEGVFEMVQKAAQNAERNQIKNIEFF 345
Cdd:pfam01135 50 IGYGQTISAPhMHAMMLELLELKPGMRVLEIGSGSGYLTACFArmvGEVGRVVSIEHIPELVEIARRNLEKLGLENVIVV 129
|
...
gi 1723812 346 QAD 348
Cdd:pfam01135 130 VGD 132
|
|
| PRK07580 |
PRK07580 |
Mg-protoporphyrin IX methyl transferase; Validated |
245-351 |
9.04e-06 |
|
Mg-protoporphyrin IX methyl transferase; Validated
Pssm-ID: 236059 [Multi-domain] Cd Length: 230 Bit Score: 46.75 E-value: 9.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 245 EQIYGDAPYYqfsdgiKLHFDIRDFIQVnsalnepMVNTALDWLELSQQ--DC-VLDLFCGMGNFTLPLAKRVKSAVGIE 321
Cdd:PRK07580 26 ARIYSDAPVS------KVRATVRAGHQR-------MRDTVLSWLPADGDltGLrILDAGCGVGSLSIPLARRGAKVVASD 92
|
90 100 110
....*....|....*....|....*....|.
gi 1723812 322 GVFEMVQKAAQNA-ERNQIKNIEFFQADLDQ 351
Cdd:PRK07580 93 ISPQMVEEARERApEAGLAGNITFEVGDLES 123
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
248-364 |
1.89e-05 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 44.99 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 248 YGDAPYYQFSDgiklHFDIRDFIQVNSALNEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIEGVFEMV 327
Cdd:COG4976 6 YVEALFDQYAD----SYDAALVEDLGYEAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEML 81
|
90 100 110
....*....|....*....|....*....|....*..
gi 1723812 328 QKAAQNAERnqiknIEFFQADldqsFVEQPWANQSFN 364
Cdd:COG4976 82 AKAREKGVY-----DRLLVAD----LADLAEPDGRFD 109
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
328-374 |
3.62e-05 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 45.69 E-value: 3.62e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1723812 328 QKAAQNAERNQIKNIEFFQADLDQSFVEQPWANQSFNKILLDPPRSG 374
Cdd:PRK14901 291 KKLQENAQRLGLKSIKILAADSRNLLELKPQWRGYFDRILLDAPCSG 337
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
286-371 |
5.10e-05 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 44.37 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 286 DWLELSQQDCVLDLFCGMGNFTLPLAKRVKSA--VGIEGVFEMVQKAAQNAERNQIKN-IEFFQADLDQsfVEQPWANQS 362
Cdd:COG4123 31 AFAPVKKGGRVLDLGTGTGVIALMLAQRSPGAriTGVEIQPEAAELARRNVALNGLEDrITVIHGDLKE--FAAELPPGS 108
|
....*....
gi 1723812 363 FNKILLDPP 371
Cdd:COG4123 109 FDLVVSNPP 117
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
297-363 |
9.36e-05 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 41.11 E-value: 9.36e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1723812 297 LDLFCGMGNFTLPLAKRVKSAVGIEGVFEMVQKAAQNAERNQIKnieFFQADLDqsfvEQPWANQSF 363
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT---FVVGDAE----DLPFPDNSF 60
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
285-376 |
1.03e-04 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 42.87 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 285 LDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSA--VGIEgVFEM-VQKAAQNAERNQIKNIEFFQADLDqsfveQPWANQ 361
Cdd:COG2813 42 LEHLPEPLGGRVLDLGCGYGVIGLALAKRNPEArvTLVD-VNARaVELARANAAANGLENVEVLWSDGL-----SGVPDG 115
|
90
....*....|....*.
gi 1723812 362 SFNKILLDPP-RSGAA 376
Cdd:COG2813 116 SFDLILSNPPfHAGRA 131
|
|
| RrnaAD |
pfam00398 |
Ribosomal RNA adenine dimethylase; |
277-349 |
1.49e-04 |
|
Ribosomal RNA adenine dimethylase;
Pssm-ID: 395321 [Multi-domain] Cd Length: 263 Bit Score: 43.12 E-value: 1.49e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1723812 277 NEPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIE---GVFEMVQKAAQNAERNQIKNIEFFQADL 349
Cdd:pfam00398 15 DPKVINEIVDKANLRESDTVLEIGPGKGALTVILAKRAKQVVAIEidpRLAKLLQKKLSLDENLTVIHQDFLKFEF 90
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
278-367 |
2.56e-04 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 41.45 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 278 EPMVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVK-SAVGIEGVFEMVQKAAQNAERNQIKN-IEFFQADLdqsfvE 355
Cdd:COG2230 37 EAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGvRVTGVTLSPEQLEYARERAAEAGLADrVEVRLADY-----R 111
|
90
....*....|..
gi 1723812 356 QPWANQSFNKIL 367
Cdd:COG2230 112 DLPADGQFDAIV 123
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
284-363 |
3.25e-04 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 42.06 E-value: 3.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 284 ALDWLELSQQDCVLDLFCGMGNFTLPLAKRVK---SAVGIEGVFEMVQKAAQNA-ERNQIKNIEFFQADldqsfVEQ-PW 358
Cdd:PRK00216 43 TIKWLGVRPGDKVLDLACGTGDLAIALAKAVGktgEVVGLDFSEGMLAVGREKLrDLGLSGNVEFVQGD-----AEAlPF 117
|
....*
gi 1723812 359 ANQSF 363
Cdd:PRK00216 118 PDNSF 122
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
289-350 |
5.25e-04 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 41.47 E-value: 5.25e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1723812 289 ELSQQDCVLDLFCGMGNFTLPLAKRVKS---AVGIEGVFEMVQKAAQNAERNQIKNIEFFQADLD 350
Cdd:PRK11873 74 ELKPGETVLDLGSGGGFDCFLAARRVGPtgkVIGVDMTPEMLAKARANARKAGYTNVEFRLGEIE 138
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
280-371 |
6.94e-04 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 40.32 E-value: 6.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 280 MVNTAldwlELSQQDCVLDLFCGMGnfTLPL-AKRVK-SAVGIEGVFEMVQKAAQNAERNQIKNIEFFQADldqsFVEQP 357
Cdd:COG1041 18 LVNLA----GAKEGDTVLDPFCGTG--TILIeAGLLGrRVIGSDIDPKMVEGARENLEHYGYEDADVIRGD----ARDLP 87
|
90
....*....|....
gi 1723812 358 WANQSFNKILLDPP 371
Cdd:COG1041 88 LADESVDAIVTDPP 101
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
284-363 |
8.30e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 40.69 E-value: 8.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 284 ALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKS---AVGIEGVFEMVqKAAQNAERNQIKNIEFFQADLDQSfveqPWAN 360
Cdd:PRK08317 11 TFELLAVQPGDRVLDVGCGPGNDARELARRVGPegrVVGIDRSEAML-ALAKERAAGLGPNVEFVRGDADGL----PFPD 85
|
...
gi 1723812 361 QSF 363
Cdd:PRK08317 86 GSF 88
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
280-349 |
1.24e-03 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 40.53 E-value: 1.24e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1723812 280 MVNTALDWLELSQQDCVLDLFCGMGNFTLPLAKRVKSAVGIeGVfEMVQKA----AQNAERNQIKNIEFFQADL 349
Cdd:PRK09328 96 LVEWALEALLLKEPLRVLDLGTGSGAIALALAKERPDAEVT-AV-DISPEAlavaRRNAKHGLGARVEFLQGDW 167
|
|
| RlmK |
COG1092 |
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ... |
289-396 |
1.47e-03 |
|
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440709 [Multi-domain] Cd Length: 392 Bit Score: 40.55 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 289 ELSQQDCVLDLFCGMGNFTLPLAKR-VKSAVGIEGVFEMVQKAAQNAERNQIK-NIEFFQAD----LDQsFVEQpwaNQS 362
Cdd:COG1092 213 ELAKGKRVLNLFSYTGGFSVHAAAGgAKSVTSVDLSATALEWAKENAALNGLDdRHEFVQADafdwLRE-LARE---GER 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1723812 363 FNKILLDPPrsgaAFA---------------LNALCE--LKAEKILYVSCN 396
Cdd:COG1092 289 FDLIILDPP----AFAkskkdlfdaqrdykdLNRLALklLAPGGILVTSSC 335
|
|
| RsmD |
COG0742 |
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
296-393 |
7.24e-03 |
|
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 440505 [Multi-domain] Cd Length: 183 Bit Score: 37.37 E-value: 7.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723812 296 VLDLFCGMGNFTLPLAKR-VKSAVGIEGVFEMVQKAAQNAER-NQIKNIEFFQADLdQSFVEQPwANQSFNKILLDPP-R 372
Cdd:COG0742 45 VLDLFAGSGALGLEALSRgAASVVFVEKDRKAAAVIRKNLEKlGLEDRARVIRGDA-LRFLKRL-AGEPFDLVFLDPPyA 122
|
90 100
....*....|....*....|....*
gi 1723812 373 SGAAF-ALNALCE---LKAEKILYV 393
Cdd:COG0742 123 KGLLEkALELLAEnglLAPGGLIVV 147
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
296-348 |
8.46e-03 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 37.92 E-value: 8.46e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1723812 296 VLDLFCGMGNFTLPLAKR-VKSAVGIE---GVFEMVQKaaqNAERNQIK-NIEFFQAD 348
Cdd:COG2520 184 VLDMFAGVGPFSIPIAKRsGAKVVAIDinpDAVEYLKE---NIRLNKVEdRVTPILGD 238
|
|
| |
