NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1721521171|gb|QEB28059|]
View 

transferrin-binding protein [Mannheimia haemolytica]

Protein Classification

lactoferrin/transferrin family TonB-dependent receptor( domain architecture ID 11493155)

lactoferrin/transferrin family TonB-dependent receptor similar to Neisseria meningitidis TbpA, an integral outer membrane protein component of the transferrin transport system that promotes iron release from transferrin

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
 1-928 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


:

Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1407.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   1 MKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQILGI 80
Cdd:TIGR01776   3 MKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  81 RDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGASS 157
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGANS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 158 AEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEANKL 237
Cdd:TIGR01776 162 SEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDANKG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 238 KHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTEQL 317
Cdd:TIGR01776 242 VQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHEQV 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 318 SAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEGDN 394
Cdd:TIGR01776 309 SAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLGDN 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 395 ILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK 471
Cdd:TIGR01776 389 YLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKVDK 468

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 472 NCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSYRG 551
Cdd:TIGR01776 469 NCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESIRG 544

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 552 RGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPWTL 628
Cdd:TIGR01776 545 DEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRLVY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 629 SRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFKGQ 708
Cdd:TIGR01776 625 SGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFKGD 702

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 709 FGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNRVK 782
Cdd:TIGR01776 703 FGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIK 782

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 783 VKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLTGS 859
Cdd:TIGR01776 783 VKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLSRS 861

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1721521171 860 WYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 928
Cdd:TIGR01776 862 WYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
 1-928 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1407.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   1 MKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQILGI 80
Cdd:TIGR01776   3 MKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  81 RDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGASS 157
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGANS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 158 AEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEANKL 237
Cdd:TIGR01776 162 SEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDANKG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 238 KHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTEQL 317
Cdd:TIGR01776 242 VQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHEQV 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 318 SAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEGDN 394
Cdd:TIGR01776 309 SAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLGDN 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 395 ILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK 471
Cdd:TIGR01776 389 YLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKVDK 468

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 472 NCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSYRG 551
Cdd:TIGR01776 469 NCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESIRG 544

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 552 RGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPWTL 628
Cdd:TIGR01776 545 DEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRLVY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 629 SRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFKGQ 708
Cdd:TIGR01776 625 SGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFKGD 702

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 709 FGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNRVK 782
Cdd:TIGR01776 703 FGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIK 782

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 783 VKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLTGS 859
Cdd:TIGR01776 783 VKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLSRS 861

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1721521171 860 WYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 928
Cdd:TIGR01776 862 WYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 71-928 3.13e-96

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 316.32  E-value: 3.13e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  71 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtLGSDANGGAINEIEYENIRSIE 150
Cdd:cd01347     9 DIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLA-----SSNYGRGVDLNTIPPELIERVE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 151 LSKGASSAEYGSGALGGAIGFRTKDAQDiiKEGQHWGLD--SKTSYASKNSHFLQSIAAAGEaGGFEALVIATHRHGKET 228
Cdd:cd01347    84 VLKGPSSALYGSGAIGGVVNIITKRPTD--EFGGSVTAGygSDNSGSSGGGGFDVSGALADD-GAFGARLYGAYRDGDGT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 229 KIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqle 308
Cdd:cd01347   161 IDGD---------------------------------------------------------------------------- 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 309 qipyrteqlsaqeytgkdrIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSL-RN 387
Cdd:cd01347   165 -------------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPsSN 225

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 388 YVYEGDNILDGLVFKPripYGLRYSHvkFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlhcsdyp 467
Cdd:cd01347   226 TNGDRDWDYRDRYRKR---ASLGLEH--DLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAA------------------ 282

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 468 vvdkncrptldkswsMYRTERNNYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmTAQYTKGGYT 547
Cdd:cd01347   283 ---------------GGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREE--------LDEKQTALYA 339

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 548 SYRGRgrldnpyiyrrdprsietvslcnntrgdilnceprkikgdshfvsfrdlvISEYVDLGLGVRFDQHRFKSDD--- 624
Cdd:cd01347   340 QDTIE--------------------------------------------------LTDDLTLTLGLRYDHYDQDSKDtia 369

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 625 -PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHiglkdneYVQRAQRSHQLEPEKSTNHEIGV 703
Cdd:cd01347   370 gGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH-------GGTAAVGNPNLKPEKSKQYELGL 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 704 SFK-GQFGYLDVSYFRNNYKNMIATAckRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGilsmlPDGFYSSVAYNRVK 782
Cdd:cd01347   443 KYDpGDGLTLSAALFRIDIKNEIVST--PTNTGLGLVTVYVNGGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTE 515

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 783 VKERKltdsrlDSVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRhhgihrvdlgGKLTGSWYT 862
Cdd:cd01347   516 VKRTD------GATTGNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADTANGNN----------TVKVPGYTL 579

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1721521171 863 HDITGYINY-KNYTLRGGIYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMKF 928
Cdd:cd01347   580 VDLSASYQFtKNLTLRLGVNNLFDKDYYTSLSV-----------RGSGLYGYYGPGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
41-902 4.23e-43

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 167.31  E-value: 4.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  41 LDEVIVTESHyAHERQNEVTGLGKVVkNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGYAIRGV--DKNRVSLLVD 118
Cdd:COG1629     1 LEEVVVTATR-TDESLQDVPGSVSVI-SREQLEDQPATDLGDLLRRVPGVSV-TSAGGGAGQISIRGFggGGNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 119 GLPQAqhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDiikegqHWGLDSKTSYASkN 198
Cdd:COG1629    78 GVPLN------DPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGS-Y 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 199 SHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldc 278
Cdd:COG1629   145 GTYRASLSLSGGNGKLAYRLSASYRDSDGYRDNS---------------------------------------------- 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 279 tprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAIL 358
Cdd:COG1629   179 -------------------------------------------------------DSDRYNLRAKLGYQLGDDTRLTLSA 203

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 359 EDTKQRYDirdmqTPAYYTKDdiNLSLRNYVYEGDNildglvfkpriPYGLRYSHVKFfderhhkRRLGFTYKYKPENNR 438
Cdd:COG1629   204 SYSDSDQD-----SPGYLTLA--ALRPRGAMDDGTN-----------PYSNDTDDNTR-------DRYSLSLEYEHLGDG 258

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 439 WldSIKLSADkqdielYSRLHRLHCSDYPVVDKNCRptldkswsmyRTERNNYQEKHRVIHLEFDKALNagqgvFKQTHK 518
Cdd:COG1629   259 L--KLSASAY------YRYDDTDLDSDFTPTPADGG----------TLEQTDFDNRTYGLELRLTYDLG-----FGGKHT 315

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 519 LNLGLGFDRFnslmdhgdmtaQYTKGGYTSYRGRGRLDNPYIYRRDPRSIETVSLcnntrgdilnceprkikgdshFVSF 598
Cdd:COG1629   316 LLVGLDYQRQ-----------DLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLAL---------------------YAQD 363

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 599 rDLVISEYVDLGLGVRFDQHRFKSDDPWT------LSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRD 672
Cdd:COG1629   364 -TYKLTDKLTLTAGLRYDYVSYDVDDTVTgtdsasGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGT 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 673 HIGLKDNEyvqraqrshQLEPEKSTNHEIGVSFKGQFGYL--DVSYFRNNYKNMIATACKRIIQKSHCFYNyhNIQDVAL 750
Cdd:COG1629   443 DPYSVGNP---------DLKPETSTNYELGLRYRLLDGRLslSLALFYSDVDNEILSVPLPNDSGFSTYYT--NAGKARS 511

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 751 NGINLVAKFDLHgilsmlpDGFYSSVAYNRVKVKERKLTDSRLDSVNDPiLDAIQPARYVLGFGYDHPeEKWGIGITTTY 830
Cdd:COG1629   512 YGVELELSYQLT-------PGLSLNASYSYTDAKFDDDTDGSADLDGNR-LPGVPPLTANLGLTYEFP-GGWSLGLGVRY 582

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1721521171 831 SKAKNADEVAGTRHH-GIHRVDLGGkltgswythditGYINYKNYTLRGGIYNVTNRKYSTWESVRQSGVNAV 902
Cdd:COG1629   583 VGDRYLDDANTQGAPgGYTLVDLGA------------GYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGF 643
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 415-927 1.56e-36

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 144.53  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 415 KFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK-----NCRPTLDKSWSMYRTERN 489
Cdd:pfam00593   4 LSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRkrlslGYDYDLGDGLSWLSTLRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 490 NYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNSL---MDHGDMTAQYTKGGYTSYRGRGRLDNPYIYRRDPR 566
Cdd:pfam00593  84 GLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 567 SIETvslcnntrgdilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPW----TLSRTYRNWSWNGGI 641
Cdd:pfam00593 164 SSSY----------------SDTTTDSYGLYLQDNIkLTDRLTLTLGLRYDHYSTDGDDGNgggdNFSRSYSAFSPRLGL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 642 TLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGlkdneYVQRAQRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNY 721
Cdd:pfam00593 228 VYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGG-----GGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 722 KNMIATAcKRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGILsmlpdGFYSSVAYNRVKVKERKLTDSRLdsvndpiL 801
Cdd:pfam00593 303 KNLITSD-PDGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLG-----LSGGGYTYTDADDDADADDTGNP-------L 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 802 DAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNAdevagtrhhgiHRVDLGGKL-TGSWYTHDIT-GYINYKNYTLRGG 879
Cdd:pfam00593 370 PNVPRHTANLGLTYDFPLGGWGARLGARYVGSGER-----------RYGDAANTFkTPGYTLVDLSaGYRLNKNLTLRLG 438

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 1721521171 880 IYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMK 927
Cdd:pfam00593 439 VNNLFDKYYKRYYSS-----------GGGNLGGYPGPGRTFYLGLSYK 475
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
82-178 3.51e-07

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 54.23  E-value: 3.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  82 DLTRYDPGISVVEQG-RGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDanggaINEIEYENIRSIELSKGASSAEY 160
Cdd:PRK10641   64 DVLRRLPGVDIAQNGgLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSAD-----LSQIPISLVQRIEYIRGPRSAVY 138

                          90
                  ....*....|....*...
gi 1721521171 161 GSGALGGAIGFRTKDAQD 178
Cdd:PRK10641  139 GSDAIGGVVNIITTRDKP 156
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
 1-928 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1407.65  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   1 MKYHHFRYSPVALTVLFALSHsYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQILGI 80
Cdd:TIGR01776   3 MKKHVLNLSILALSLLFATLS-FQTADADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  81 RDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSD---ANGGAINEIEYENIRSIELSKGASS 157
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRsgtAGSGAINEIEYENVRSVEISKGANS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 158 AEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSEANKL 237
Cdd:TIGR01776 162 SEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDANKG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 238 KHNIRRITGFENRYDLYPnsaqnaPGGSFFIVEDTCPTLDCTPRARVKLNRDNFpvrtfpeYTPEERKQLEQIPYRTEQL 317
Cdd:TIGR01776 242 VQSIDRLDAFEQKYDLRP------PQGRSFIVENECASLDCAPCAQYGYVYDNQ-------LSDEEKAQVLASRYRHEQV 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 318 SAQEYTGKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNY---VYEGDN 394
Cdd:TIGR01776 309 SAKDYTGENRLLPNPLDYRSDSWLAKLGYHLNNRHYVGGVLEDTKQRYDIRDMTEPAYLGLSDAVKGRLKNgggIYLGDN 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 395 ILDGLVFK--PRIPYGLRYSHVKFFDERHHKRRLGFTYKYKPEN-NRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK 471
Cdd:TIGR01776 389 YLEGLNFNagPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDyDRWLDTAKLSLDKQKIELRSRLQELHCSQYPKVDK 468

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 472 NCRPTLDKSWSMYRTERNNYQEKHRVIHLEFDKALNAGQGvfkqTHKLNLGLGFDRFNSLMDHGDMTAQYTKGGYTSYRG 551
Cdd:TIGR01776 469 NCRPSLDKPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGG----RHHLNLLLGYDKFKSQLSRHDYRRQNAVGTYESIRG 544

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 552 RGRLDNPYIYRRDPRSIETVSLCN--NTRGDILNCEPRKIKGDSHFVSFRD-LVISEYVDLGLGVRFDQHRFKSDDPWTL 628
Cdd:TIGR01776 545 DEPKQNPYKYRLGKATIVKNSLCRysETNGYANCCEPRKIKGSNHYISLNDnFTIGKYVDLGLGGRYDKHNFKSTDRLVY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 629 SRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLKDNeyVQRAQRSHQLEPEKSTNHEIGVSFKGQ 708
Cdd:TIGR01776 625 SGTYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASKKN--VQQFLRTPDLKPEKSLNHEIGARFKGD 702

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 709 FGYLDVSYFRNNYKNMIATA-CKRI-----IQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSMLPDGFYSSVAYNRVK 782
Cdd:TIGR01776 703 FGHLEVSYFRNRYKDMIAEApETRTdneagQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIK 782

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 783 VKERKLTDSRLDsVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVD---LGGKLTGS 859
Cdd:TIGR01776 783 VKEVKNRAGRLD-VRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVkqtATKKLSRS 861

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1721521171 860 WYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAVNQDRG-SNYTRFAAPGRNFSLAFEMKF 928
Cdd:TIGR01776 862 WYTLDVTGYVNlKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGvSNYNRYAAPGRNYSLSLEMKF 932
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 44-928 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 711.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  44 VIVTESHYAHERQNEVTGLGKVVKNYHEMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQA 123
Cdd:TIGR01786   5 VTATRTADPQRRDLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRGGSQGINIRGLDKNRVAVLVDGIRQN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 124 QHYHtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTSYASKNSHFLQ 203
Cdd:TIGR01786  85 TSYG--GQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSSANNRFTQ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 204 SIAAAGEAGGFEALVIATHRHGKETKIHSEANKLKHnirritgfenrydlypnsaqnapggsffivedtcptldctprar 283
Cdd:TIGR01786 163 SVAAAGRNDDVDALVQATYRRGHELKNGNKANIGNE-------------------------------------------- 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 284 vklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgKDRIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQ 363
Cdd:TIGR01786 199 -----------------------------------------SKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSLEYTQT 237

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 364 RYDIRDMQTPAYYTKDDINLslrnyvyegdnildglvfkpripygLRYSHVKFFDERHHKRRLGFTYKYKPENnRWLDSI 443
Cdd:TIGR01786 238 DYDEPEMTNTSYLTKPLGAP-------------------------LLSSTVVLGDSKTRDRRTGLDYELNPDN-SWLDTV 291

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 444 KLSADKQDIELYSRLHRLHCSDYPVVDKNCRptldkswsmyrternnYQEKHRVIHLEFDKALNAGQGVfkqtHKLNLGL 523
Cdd:TIGR01786 292 KLALDKQYIQLYNYLNATSASDYPGVDKNGR----------------YKDKYDYYTLGFDTNNKIEFSV----HSLSLTY 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 524 GFDRFNSLMDHGDMTAQYTKGGYTSYRGRGrldnpyiyrrdprsietvslcnntrgdilncEPRKIKGDSHFVSFRD-LV 602
Cdd:TIGR01786 352 GLDRFKDKVSTGDSRRNLPTAAYNLYGYEG-------------------------------ENRPVKGSNFGLFLQDnIK 400

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 603 ISEYVDLGLGVRFDQHRFK-----SDDPWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGLK 677
Cdd:TIGR01786 401 LGDWLSLSAGLRYDHYKTDpkadeSKDYGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGG 480

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 678 DNEYVqraqRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNYKNMIATACKRI------IQKSHCFYNYHNIQDVALN 751
Cdd:TIGR01786 481 PYTFL----PNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGVTakgnmaQVGSNTITNYVNIDNARIR 556

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 752 GINLVAKFDLHGILSMlPDGFYSSVAYNRVKVKERKltdsrldsvNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYS 831
Cdd:TIGR01786 557 GIELSGRYDLGSFFSG-PDGWTTTLKYGYTKGKDSD---------TNPWLNAITPLKVVLGLGYDHPDEKWGVGLTLTFS 626

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 832 KAKNADEVAGTRHHGIHRVDLGGKLTGSWYTHDITGYIN-YKNYTLRGGIYNVTNRKYSTWESVRQSGVNAvnqdrgsny 910
Cdd:TIGR01786 627 GAKDAVDAYATYYENGEAAKAGPLRTPSYTVVDLYGYYKpNKNLTLRFGVYNLLDRKYTTWESARQAGPLA--------- 697

                         890
                  ....*....|....*...
gi 1721521171 911 TRFAAPGRNFSLAFEMKF 928
Cdd:TIGR01786 698 TGYTAPGRNYKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 71-928 3.13e-96

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 316.32  E-value: 3.13e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  71 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtLGSDANGGAINEIEYENIRSIE 150
Cdd:cd01347     9 DIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLA-----SSNYGRGVDLNTIPPELIERVE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 151 LSKGASSAEYGSGALGGAIGFRTKDAQDiiKEGQHWGLD--SKTSYASKNSHFLQSIAAAGEaGGFEALVIATHRHGKET 228
Cdd:cd01347    84 VLKGPSSALYGSGAIGGVVNIITKRPTD--EFGGSVTAGygSDNSGSSGGGGFDVSGALADD-GAFGARLYGAYRDGDGT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 229 KIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqle 308
Cdd:cd01347   161 IDGD---------------------------------------------------------------------------- 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 309 qipyrteqlsaqeytgkdrIAPNPLDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSL-RN 387
Cdd:cd01347   165 -------------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPsSN 225

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 388 YVYEGDNILDGLVFKPripYGLRYSHvkFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlhcsdyp 467
Cdd:cd01347   226 TNGDRDWDYRDRYRKR---ASLGLEH--DLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAA------------------ 282

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 468 vvdkncrptldkswsMYRTERNNYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmTAQYTKGGYT 547
Cdd:cd01347   283 ---------------GGDLGRSGYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREE--------LDEKQTALYA 339

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 548 SYRGRgrldnpyiyrrdprsietvslcnntrgdilnceprkikgdshfvsfrdlvISEYVDLGLGVRFDQHRFKSDD--- 624
Cdd:cd01347   340 QDTIE--------------------------------------------------LTDDLTLTLGLRYDHYDQDSKDtia 369

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 625 -PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDHiglkdneYVQRAQRSHQLEPEKSTNHEIGV 703
Cdd:cd01347   370 gGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSH-------GGTAAVGNPNLKPEKSKQYELGL 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 704 SFK-GQFGYLDVSYFRNNYKNMIATAckRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGilsmlPDGFYSSVAYNRVK 782
Cdd:cd01347   443 KYDpGDGLTLSAALFRIDIKNEIVST--PTNTGLGLVTVYVNGGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTE 515

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 783 VKERKltdsrlDSVNDPILDAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNADEVAGTRhhgihrvdlgGKLTGSWYT 862
Cdd:cd01347   516 VKRTD------GATTGNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADTANGNN----------TVKVPGYTL 579

                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1721521171 863 HDITGYINY-KNYTLRGGIYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMKF 928
Cdd:cd01347   580 VDLSASYQFtKNLTLRLGVNNLFDKDYYTSLSV-----------RGSGLYGYYGPGRTYYLSVSYKF 635
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 41-928 3.47e-53

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 197.61  E-value: 3.47e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  41 LDEVIVTEshyAHERQNEVTGLGKVVKnyheMSKNQILG-----IRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSL 115
Cdd:TIGR01785   1 LDTVTVTA---TRTRQVLSEAPASVSV----ISGEQIESkqannLADALNTVPGVDVTGGGRPPGQSINIRGLQDNRVLV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 116 LVDGLPQA--QHYHTLGSdanggaiNEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTS 193
Cdd:TIGR01785  74 VVDGARQNyqRGGAHNGS-------LFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLS 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 194 YASKNSHFLQSIAAAGEAG-GFEALVIATHRHGketkihseanklkHNIRRITGFEnrydlypnsaqnapggsffivedt 272
Cdd:TIGR01785 147 YGSNNNSFGGSVAVAGRLDdNLDALVAATYRDG-------------GNYRNGNKEE------------------------ 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 273 cptldctprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriaPNPLDYKSNSVFMKFGYHFNSSH 352
Cdd:TIGR01785 190 ---------------------------------------------------------ATNSAYVQKNLLAKLGWQLDDAQ 212

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 353 YLGaiLEDTKQRYDIRDMQTPayYTKDDINLSLRNYVYEGDNIldglvfkpripyglRYSHVkffderhhkrrlgFTYKY 432
Cdd:TIGR01785 213 RLE--FSYFTTEGSLDEAQNS--GPGTEYVLGSSSTLLASSTR--------------DRSAT-------------LTYNW 261

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 433 KPENNRWLDSiklsadkqDIELYsrlhrlHCSDYPVVDKNCRPTLDKSWSMYRTERNNYQEKHRvihlefdkalnagqgv 512
Cdd:TIGR01785 262 TPEDNPWLDA--------TASLY------YNRTENDNDRSARGVGREEGYQYTTYGATLQNTSR---------------- 311

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 513 FKQTHKLNLGLGFDRFNSLMdhgdmtaqytkggyTSYRGRGRLDNPyIYRRDPRSIETVSlcnntrgdilnceprkikgd 592
Cdd:TIGR01785 312 FDVASWSTLTYGVDWMKDKR--------------RTESFDPNSVTT-IVPNPPSAKEYFF-------------------- 356

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 593 SHFVSFRDLVISEYVDLGLGVRFDQHRFKSD---DPWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYG 669
Cdd:TIGR01785 357 GLFLQDNIPLLDDRLTLSAGLRYDHYKLSPKttaDTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYG 436

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 670 KRDHIGLKD-NEYVQraqrSHQLEPEKSTNHEIG--VSFKGQFGYLD-----VSYFRNNYKNMI---ATACKRIIQKSHC 738
Cdd:TIGR01785 437 TGDHPGTPGgYTFAP----NPNLKPETSKTWELGanLSFDNLLLDNDqlqfkVAYFYNDVKDFIdltIGVTDNVTAGMNN 512

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 739 FYNYHNIQDVALNGINLVAKFDLhgilsmlpDGFYSSVAYNRVKVKerkltdsrlDSVNDPILDAIQPARYVLGFGYDHP 818
Cdd:TIGR01785 513 ITQYVNIDGARIRGIEASASYDA--------GLWATGLSYGYTIGK---------DQNTNQWLSNIPPLKLVVTVGYRFP 575

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 819 EEKWGIGITTTYSKAKN----ADEVAGTrhhgiHRVDlggklTGSWYTHDITGYIN---YKNYTLRGGIYNVTNRKYSTW 891
Cdd:TIGR01785 576 DRRLDLGAKAAYYERQSesptTEDVAAN-----GLLT-----TPGYTVVDLYATYQpnaVKGLTVRFGVNNLTDRKYTPA 645

                         890       900       910
                  ....*....|....*....|....*....|....*..
gi 1721521171 892 ESVRQSGvnavnqdrgsnytrfaaPGRNFSLAFEMKF 928
Cdd:TIGR01785 646 QSVPGAG-----------------PGRNFKGSVKYQF 665
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
41-902 4.23e-43

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 167.31  E-value: 4.23e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  41 LDEVIVTESHyAHERQNEVTGLGKVVkNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGYAIRGV--DKNRVSLLVD 118
Cdd:COG1629     1 LEEVVVTATR-TDESLQDVPGSVSVI-SREQLEDQPATDLGDLLRRVPGVSV-TSAGGGAGQISIRGFggGGNRVLVLVD 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 119 GLPQAqhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDiikegqHWGLDSKTSYASkN 198
Cdd:COG1629    78 GVPLN------DPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGS-Y 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 199 SHFLQSIAAAGEAGGFEALVIATHRHGKETKIHSeanklkhnirritgfenrydlypnsaqnapggsffivedtcptldc 278
Cdd:COG1629   145 GTYRASLSLSGGNGKLAYRLSASYRDSDGYRDNS---------------------------------------------- 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 279 tprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAIL 358
Cdd:COG1629   179 -------------------------------------------------------DSDRYNLRAKLGYQLGDDTRLTLSA 203

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 359 EDTKQRYDirdmqTPAYYTKDdiNLSLRNYVYEGDNildglvfkpriPYGLRYSHVKFfderhhkRRLGFTYKYKPENNR 438
Cdd:COG1629   204 SYSDSDQD-----SPGYLTLA--ALRPRGAMDDGTN-----------PYSNDTDDNTR-------DRYSLSLEYEHLGDG 258

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 439 WldSIKLSADkqdielYSRLHRLHCSDYPVVDKNCRptldkswsmyRTERNNYQEKHRVIHLEFDKALNagqgvFKQTHK 518
Cdd:COG1629   259 L--KLSASAY------YRYDDTDLDSDFTPTPADGG----------TLEQTDFDNRTYGLELRLTYDLG-----FGGKHT 315

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 519 LNLGLGFDRFnslmdhgdmtaQYTKGGYTSYRGRGRLDNPYIYRRDPRSIETVSLcnntrgdilnceprkikgdshFVSF 598
Cdd:COG1629   316 LLVGLDYQRQ-----------DLDGSGYPLDLGSGSLPTLTSGADDDGTTTSLAL---------------------YAQD 363

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 599 rDLVISEYVDLGLGVRFDQHRFKSDDPWT------LSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRD 672
Cdd:COG1629   364 -TYKLTDKLTLTAGLRYDYVSYDVDDTVTgtdsasGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGT 442

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 673 HIGLKDNEyvqraqrshQLEPEKSTNHEIGVSFKGQFGYL--DVSYFRNNYKNMIATACKRIIQKSHCFYNyhNIQDVAL 750
Cdd:COG1629   443 DPYSVGNP---------DLKPETSTNYELGLRYRLLDGRLslSLALFYSDVDNEILSVPLPNDSGFSTYYT--NAGKARS 511

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 751 NGINLVAKFDLHgilsmlpDGFYSSVAYNRVKVKERKLTDSRLDSVNDPiLDAIQPARYVLGFGYDHPeEKWGIGITTTY 830
Cdd:COG1629   512 YGVELELSYQLT-------PGLSLNASYSYTDAKFDDDTDGSADLDGNR-LPGVPPLTANLGLTYEFP-GGWSLGLGVRY 582

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1721521171 831 SKAKNADEVAGTRHH-GIHRVDLGGkltgswythditGYINYKNYTLRGGIYNVTNRKYSTWESVRQSGVNAV 902
Cdd:COG1629   583 VGDRYLDDANTQGAPgGYTLVDLGA------------GYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGF 643
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 415-927 1.56e-36

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 144.53  E-value: 1.56e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 415 KFFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKQDIELYSRLHRLHCSDYPVVDK-----NCRPTLDKSWSMYRTERN 489
Cdd:pfam00593   4 LSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRkrlslGYDYDLGDGLSWLSTLRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 490 NYQEKHRVIHLEFDKALNAGQGVFKQTHKLNLGLGFDRFNSL---MDHGDMTAQYTKGGYTSYRGRGRLDNPYIYRRDPR 566
Cdd:pfam00593  84 GLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELsldLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 567 SIETvslcnntrgdilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPW----TLSRTYRNWSWNGGI 641
Cdd:pfam00593 164 SSSY----------------SDTTTDSYGLYLQDNIkLTDRLTLTLGLRYDHYSTDGDDGNgggdNFSRSYSAFSPRLGL 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 642 TLKPTEFVSLSYRISNGFRVPAFYELYGKRDHIGlkdneYVQRAQRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNY 721
Cdd:pfam00593 228 VYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGG-----GGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 722 KNMIATAcKRIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGILsmlpdGFYSSVAYNRVKVKERKLTDSRLdsvndpiL 801
Cdd:pfam00593 303 KNLITSD-PDGPGLGGTVYTYTNVGKARIRGVELELSGRLWGLG-----LSGGGYTYTDADDDADADDTGNP-------L 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 802 DAIQPARYVLGFGYDHPEEKWGIGITTTYSKAKNAdevagtrhhgiHRVDLGGKL-TGSWYTHDIT-GYINYKNYTLRGG 879
Cdd:pfam00593 370 PNVPRHTANLGLTYDFPLGGWGARLGARYVGSGER-----------RYGDAANTFkTPGYTLVDLSaGYRLNKNLTLRLG 438

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 1721521171 880 IYNVTNRKYSTWESVrqsgvnavnqdRGSNYTRFAAPGRNFSLAFEMK 927
Cdd:pfam00593 439 VNNLFDKYYKRYYSS-----------GGGNLGGYPGPGRTFYLGLSYK 475
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 15-832 2.56e-31

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 130.75  E-value: 2.56e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  15 VLFALSHSYGAATENKKIEENNDLAVLDEVIVTESHYAHERQNevTGLGKVVKNYHEMSKNQILGIRDLTRYDPGISVVE 94
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSD--APASVSVITAEEIEKLGATDLADALRLLPGVSVTR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  95 Q-GRGASSGYAIRGVDKNRVSLLVDGLPQAQhyhtlGSDANGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRT 173
Cdd:COG4771    79 SgGRGGSSGISIRGLGGDRVLVLIDGVPVNN-----PALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIIT 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 174 KDAQDIikegqhWGLDSKTSYASKNSHFLQ-SIAAAGEAGGFEALVIATHRHGKETkihseanklkhnirritgfenryd 252
Cdd:COG4771   154 KKPTDE------LEGSVSLGYGSNGNGTYSgSLSLGGPGDKLSFLLSGSYRDRDGY------------------------ 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 253 lypnsaqnapggsffivedtcptldctprarvklnrdnfpvrtfpeytpeerkqleqipyrteqlsaqeYTGKDRIAPNP 332
Cdd:COG4771   204 ---------------------------------------------------------------------LDYRNGGFVGN 214

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 333 LDYKSNSVFMKFGYHFNSSHYLGAILEDTKQRYDIRDMQTPAYYTKDDINLSLRNYVYEGDnildglvfkpripYGLRYS 412
Cdd:COG4771   215 SGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGN-------------YSLRYN 281

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 413 HvkffderhhkrrlgftykykpennRWLDSIKLSADKQDIElysrlhrlhcsdypvvdkncRPTLDKSWSMYRTERNNYQ 492
Cdd:COG4771   282 G------------------------DLGDNLDLSLYYSRTD--------------------RDSTNGSLGGSTGSFSDSD 317

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 493 EKHRVIHLEFDKALNAGqgvfkqtHKLNLGLGFDrfnslmdhgdmtaqytkggytsyrgRGRLDNPYIYRRDPRSIETVS 572
Cdd:COG4771   318 DTTYGLELDLTYPLGGN-------HTLTLGAEYR-------------------------YDDLDSSSFLGGADASRDTYG 365

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 573 LcnntrgdilnceprkikgdshFVSFrDLVISEYVDLGLGVRFDQHRFKSDDpwtlsrTYRNWSWNGGITLKPTEFVSLS 652
Cdd:COG4771   366 L---------------------FAQD-EWKLTDKLTLTAGLRYDYYSTFGAS------NYTAFSPRLGLRYDLSDNLTLR 417

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 653 YRISNGFRVPAFYELYGKRDHIGlkdneyVQRAQRSHQLEPEKSTNHEIGVSFKGQFG--YLDVSYFRNNYKNMIATacK 730
Cdd:COG4771   418 ASYGRGFRAPSLAELYGSGTGTP------GRYVLGNPDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVL--V 489

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 731 RIIQKSHCFYNYHNIQDVALNGINLVAKFDLHGILSmlpdgFYSSVAYNRVKVKERKLTDSrldsvndpiLDAIQPARYV 810
Cdd:COG4771   490 PVGPGPGDVLQYENVGKARTYGLELELKYRLGKGLT-----LTASYTYLDSKIDDGDTGEP---------LPNVPPHKAN 555

                         810       820
                  ....*....|....*....|..
gi 1721521171 811 LGFGYDHPEEKWGIGITTTYSK 832
Cdd:COG4771   556 LGLDYRLPKWWLLLLLTRYYGG 577
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 71-168 2.06e-22

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 92.72  E-value: 2.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  71 EMSKNQILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAqhyhtlGSDANGGAINEIEYENIRSIE 150
Cdd:pfam07715  16 DIEDQGATNLADALRGVPGVSVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLN------SGGGGSVDLNSIDPEDIERVE 89

                          90
                  ....*....|....*...
gi 1721521171 151 LSKGASSAEYGSGALGGA 168
Cdd:pfam07715  90 VLKGPASALYGSGAIGGV 107
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
12-928 8.46e-20

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 94.61  E-value: 8.46e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  12 ALTVLFALSHSYGAATEnkkieenndlAVLDEVIVTESHYAHERQNEVTGLGKVVKNyHEMSKNQILGIRDLTRYDPGIS 91
Cdd:COG4772     4 ALAAALLLAAAAAAEAA----------TTLETVVVTGSRAAEARLKDVPGSVSVVDR-EELENQAATSLREVLRRVPGVN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  92 VV-EQGRGASSGYAIRGVDKNRVS---LLVDGLP---------QAQHYHTLgsdanggaineieyENIRSIELSKGASSA 158
Cdd:COG4772    73 VQeEDGFGLRPNIGIRGLGPRRSRgitLLEDGIPiapapygdpAAYYFPDL--------------ERMERIEVLRGAAAL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 159 EYGSGALGGAIGFRTKDAQDIikegqhWGLDSKTSYASkNSHFLQSIAAAGEAGGFEALVIATHRHGKetkihseanklk 238
Cdd:COG4772   139 RYGPQTVGGAINFVTRTIPTA------FGGELRVTGGS-FGYRRTHASVGGTVGNFGYLVEYSRKRGD------------ 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 239 hnirritGFenrydlypnsaqnapggsffivedtcptldctprarvklnRDNfpvrtfpeytpeerkqleqipyrteqlS 318
Cdd:COG4772   200 -------GF----------------------------------------RDN---------------------------S 205

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 319 aqeytgkdriapnplDYKSNSVFMKFGYHFNSSHYLGAILedtkQRYDIrDMQTPAYYTKDDinlslrnyvYEGDnildg 398
Cdd:COG4772   206 ---------------GFDINDFNAKLGYRLSDRQELTLKF----QYYDE-DANTPGGLTDAQ---------FDAD----- 251

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 399 lvfkPRIPYGLRYShvkfFDERHhkRRLGFTYKYKPennrwldsiklsADKQDIEL---YSRLHRLHCSDYPVVDKNCRP 475
Cdd:COG4772   252 ----PRQSYRPADQ----FDTRR--TQLSLRYEHQL------------SDNTTLTTtayYNDFSRNWYIRQNTADPNTPG 309

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 476 TLDKSwsmyrterNNYQEKHRVIHLEFDKALNAGqgvfKQTHKLNLGLgfdRFnslmDHGDMTAQYTKGGYtsyrgrGRL 555
Cdd:COG4772   310 LGLRG--------NPRGYRSYGIEPRLTHRFELG----GVPHTLEVGL---RY----HREEEDRKQYVNTY------GQG 364

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 556 DNPYIYRRDprsietvslcnntrgdilncepRKIKGDSH--FVSFR-----DLVISeyvdlgLGVRFDQHRFKSDD---- 624
Cdd:COG4772   365 RSGAGLRRD----------------------RRFSADALaaYAQNRfeltgRLTLT------PGLRYEHIRRDRTDryst 416

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 625 ----PWTLSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELygkrdhiglkdneyVQRAQRSHQLEPEKSTNHE 700
Cdd:COG4772   417 rtggDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDL--------------AYGNGGNPDLKPEKSWNYE 482

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 701 IGVSFK-GQFGYLDVSYFRNNYKNMIATackriIQKSHCFYN-YHNIQDVALNGINLVAKFDLhgiLSMLPDGFYSSVAY 778
Cdd:COG4772   483 LGTRGRiGNGLSAEVALFYIDYDNELGS-----CSAAGGDRStFTNAGETRHQGLELALDYDL---LKGGGLGLPLFAAY 554

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 779 NrvkvkerkLTDSRLDSVNDPI-----LDAIQPARYVLGFGYDHpeEKWGIGITTTYSKAKNADeVAGTRHHGIhrvdlg 853
Cdd:COG4772   555 T--------YTDAEFTSDFGPVfagnrLPYVPRHQLTAGLGYEH--GGWTANLNGRYVSEQFTD-AANTVADGS------ 617

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1721521171 854 GKLTGSWYTHDIT-GYINYKNYTLRGGIYNVTNRKYSTweSVRqsgvnaVNQDRGsnytRFAAPGRNFSLAFEMKF 928
Cdd:COG4772   618 FGKIPSYTVLDLSaSYDFGKNLSLFAGVNNLFDKRYIA--SRA------PNYAAG----IRPGPPRTVYAGLRLKF 681
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
44-224 7.04e-17

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 81.84  E-value: 7.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  44 VIVTESHYAhERQNEVTGLGKVVKNYhEMSKNQILGIRDLTRYDPGISVVEQGR-GASSGYAIRGVDKNRVSLLVDGLPq 122
Cdd:COG4206     1 VVVTATRLE-QSKSDLTGSVTVIDAE-ELERSGATSLADALRRVPGVQVSSSGGpGSAASISIRGLGSNQTLVLIDGVP- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 123 aqhyhtLGSDANGGA-INEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKDAqdiiKEGQHWGLDskTSYASkNSHF 201
Cdd:COG4206    78 ------LNDPSLGGVdLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKG----KKGFKGSVS--ASYGS-FGTR 144

                         170       180
                  ....*....|....*....|...
gi 1721521171 202 LQSIAAAGEAGGFEALVIATHRH 224
Cdd:COG4206   145 RLSASLSGGAGKFSYSLSASYRR 167
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 71-928 9.34e-16

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 81.69  E-value: 9.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  71 EMSKNQILGIRDLTRYDPGISVVE-QGRGASSGYAIRGVDKN--RVSLLVDGLPQaqhYHTLGSDAnggaineIEYENIR 147
Cdd:TIGR01783  13 ELEDQQAGSLSEALQRVPGVVVGGsGGTTQFGNITIRGFGLEvdIDNVYLDGVPL---LSRGNLAI-------VDPAMVE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 148 SIELSKGASSAEYGSGALGGAIGFRTKDAQDIIK--EGQHWGLDSktSYASKNSHFLqSIAAAGEAGG---FEALVIATH 222
Cdd:TIGR01783  83 RVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKgsVTFGAGTRS--GYRTAFDLGG-PLGADGTFRGrlnGARQDGDSF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 223 RHGKETKIHSEANKLKHNIRRITGFENRYDLYPnSAQNAPGGSFFIVEDTCPtldctPRARVKLNRDNFPVRTFPEYTpE 302
Cdd:TIGR01783 160 YDGAGEETRLGATATDWQLDDRTLLRLGAYYQK-ERDRGGYGGLPASGGTSG-----RDLSSDRYLGTSSNRNYDDRE-Y 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 303 ERKQleqipYRTEQLSAQEYTGKDRIAPNPLDYKSNSVFMkfgyhfnsshylGAILEDTKQrydirdmqtpayytkDDIN 382
Cdd:TIGR01783 233 LSYG-----LSLEYQFNDVWTGKQNLRYSYFDTDSNQVQA------------SGYSSDGGL---------------FGRS 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 383 LSLRNYVYEGDNILDGLVFKpripyglryshvkfFDERHHKRRLGFTYKYKPENNRWLDSIKLSADKqdielysrlhrlh 462
Cdd:TIGR01783 281 LTVVNVKQDRVQIDAGLDGE--------------FETGPIEHDLLLGVSYGQRTTNRFNNTGYPSDN------------- 333

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 463 cSDYPVVDKNCRPTLDKSWSMYRTErnnyqekhrvihlefdkalnagqgvfkqthklnlglgfdrfnslmdhgdmTAQYT 542
Cdd:TIGR01783 334 -IYSLTATSSARTDIGDSPKDRALS--------------------------------------------------STTKA 362

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 543 KGGYTsyrgrgrldnpyiyrrdprsietvslcnntrgdilncEPRKIKGDShfvsfrdlviseyVDLGLGVRFDQHRFKS 622
Cdd:TIGR01783 363 LNGVA-------------------------------------LQRILLADK-------------WTLTLGGRYDSVDVKS 392

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 623 DDPWTLS---RTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYELYGKRDhiglkdneyvqraqrSHQLEPEKSTNH 699
Cdd:TIGR01783 393 NNGVAGStgkRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNS---------------GDILEPEKGKNY 457

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 700 EIGVSFKGQFGYL-DVSYFRNNYKNMIATACKRIiqkshcfYNYHNIQDVALNGINLVAKFDLHGILSMlpdgfYSSVAY 778
Cdd:TIGR01783 458 ELGVRYDLGDSLLaTAALFRITKDNQLVQDPVNG-------TFSVNAGKTRNRGVELEARGYLTPGLSL-----SAGYTY 525

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 779 NRVKVKERKLTDSRLDsvndpilDAIQPARYVLGFG--YDHPEEKWGIGITTT--YSKAKNADEVAGTRHHGIHRVDLGg 854
Cdd:TIGR01783 526 TDAEFTEDTNGDTQGN-------TVPFVPKHTASLWasYAPPVGDNGLTLGGGvqYTGKAYVDGGNTGKVPSYTVVDLS- 597

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1721521171 855 kltGSWythDITgyiNYKNYTLRGGIYNVTNRKYstWESVrqsgvnavnQDRGSNYTRFAAPGRNFSLAFEMKF 928
Cdd:TIGR01783 598 ---VRY---DLT---KKKNLTLALNVNNLFDRDY--YTSG---------YRWGPSAYIYPGAPRTVGLSVSYDF 651
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
76-928 6.55e-14

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 75.68  E-value: 6.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  76 QILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDkNRVSLLVDGLPQAQHYHtlgsdanggaineIEYENIRSIELSKGA 155
Cdd:COG4774    25 GATSLADALRNVPGVTFGAGEGGNGDSFSIRGFS-ASGDIYVDGLRDPGQYR-------------RDTFNLERVEVLKGP 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 156 SSAEYGSGALGGAIGFRTKDAQDiikegqhwglDSKTSYAsknshflqsiAAAGEAGGFEALVIATHRHGKETKIhsean 235
Cdd:COG4774    91 ASVLYGRGSPGGVINLVTKRPTD----------EPFTEVT----------LTYGSDGQRRATLDVNGPLGDDLAY----- 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 236 klkhnirRITGfenrydlypnSAQNapGGSFfivedtcptldctpRARVKLNRDNfpvrtfpeytpeerkqleqipyrte 315
Cdd:COG4774   146 -------RLNG----------MYRD--SDSY--------------RDGVDNDRWG------------------------- 167

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 316 qlsaqeytgkdrIAPNpLDYKSNSvfmkfgyhfNSSHYLGAILEDTKQRYdirDMQTPAYYTKDDINLSLRNYvyegdni 395
Cdd:COG4774   168 ------------IAPS-LTWRLGD---------RTRLTLDYEYQDDDRTP---DYGVPAVANGRPVDVDRSTF------- 215

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 396 ldglvfkpripYGLRYShvkFFDERHHkrRLGFTYKYKPeNNRWldSIKLSAdkqdieLYSRLHRlhcsDYPVVdkncRP 475
Cdd:COG4774   216 -----------YGQPDD---YSDSETD--SATLRLEHDF-NDNW--TLRNAL------RYSDYDR----DYRNT----YP 262

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 476 TLDKSWSMYRTERNNYQEKHRVIHLEFDkaLNAGQGVFKQTHKLNLGLGFDRFNslmdhgdmtaqYTKGGYTSYRGRGRL 555
Cdd:COG4774   263 TGGNATGTVTRSAYRRDQDNDTLSNQTD--LTGKFDTGGVKHTLLAGVEYSRED-----------SDNARYSGGGTAPTV 329

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 556 DnpyIYrrDPRSIETVSLCNNTRGDilncepRKIKGDSHFVSFRDLV-ISEYVDLGLGVRFDQHRFKSDDPWT----LSR 630
Cdd:COG4774   330 N---LY--NPVYGAPVTGPTLGGAD------NDSRTDTTGLYLQDTIsLTDRWSLLAGLRYDRFDTDYTDRTTgattSSY 398

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 631 TYRNWSWNGGITLKPTEFVSL--SYriSNGFRVPAfyelygkrdhiglkdnEYVQRAQRSHQLEPEKSTNHEIGV---SF 705
Cdd:COG4774   399 DDSAFSPRAGLVYKPTPNLSLyaSY--STSFNPGG----------------GAPSLSNAGQALDPEKSRQYEVGVkwdLL 460

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 706 KGQFGyLDVSYFRNNYKNMIATackriiqkshcfyNYHNIQDVALNGINLVAKFDLhGILSMLPDGF--YSSVAYnrvkv 783
Cdd:COG4774   461 DGRLS-LTAALFRIEKTNVRTT-------------DPANPGVYVQTGEQRSRGVEL-EATGELTPGWsvLAGYTY----- 520

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 784 kerklTDSRLDSVNDPILD---AIQPARYVLGFG--YDHPEEKWGIGITTTYSKAKNADEVAGTRHHGIHRVDLGgkltg 858
Cdd:COG4774   521 -----LDAEITKSANAANVgnrLPNVPRHSASLWttYDLPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAG----- 590

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 859 swythdiTGYINYKNYTLRGGIYNVTNRKYstWESVRQSGVNAVnqdrgsnytrfaAPGRNFSLAFEMKF 928
Cdd:COG4774   591 -------ASYRLNKNLTLRLNVNNLTDKRY--YASAYGSGYVTP------------GAPRTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 76-178 7.93e-09

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 59.52  E-value: 7.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  76 QILGIRDLTRYDPGISVVEQGRGASSGYAIRGVDKNRVslLVDGLPQaqhyhtlgsdaNGGAINEIEYENIRSIELSKGA 155
Cdd:COG4773    81 GATTLDDALRNVPGVTVSSYDGGGRDSFSIRGFSIDNY--LRDGLPL-----------GGFGGGQPDTANLERVEVLKGP 147

                          90       100
                  ....*....|....*....|...
gi 1721521171 156 SSAEYGSGALGGAIGFRTKDAQD 178
Cdd:COG4773   148 AGLLYGAGSPGGLVNLVTKRPTA 170
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
82-178 3.51e-07

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 54.23  E-value: 3.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  82 DLTRYDPGISVVEQG-RGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDanggaINEIEYENIRSIELSKGASSAEY 160
Cdd:PRK10641   64 DVLRRLPGVDIAQNGgLGQLSSLFIRGTNSSHVLVLIDGVRLNQAGISGSAD-----LSQIPISLVQRIEYIRGPRSAVY 138

                          90
                  ....*....|....*...
gi 1721521171 161 GSGALGGAIGFRTKDAQD 178
Cdd:PRK10641  139 GSDAIGGVVNIITTRDKP 156
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
608-725 1.12e-06

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 52.72  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 608 DLGLGVRFDQHrfksddpwtlSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYE------LYGKRD--HIGLKDN 679
Cdd:PRK13524  448 MLTPGLRFDHH----------SIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQtnpnyiLYSKGQgcYASAGNG 517

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1721521171 680 EYVQRaqrSHQLEPEKSTNHEIGVSFKgQFGYL-DVSYFRNNYKNMI 725
Cdd:PRK13524  518 CYLQG---NDDLKAETSVNKEIGLEFK-RDGWLaGLTWFRNDYRNKI 560
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 40-186 5.75e-06

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 50.27  E-value: 5.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  40 VLDEVIVTEShyAHErQNEVTGLGKV-VKNYHEMSKNQILGIRDLTRYDPGISVVEQGRGaSSGYAIRGVDKNRVSLLVD 118
Cdd:PRK10064   29 DGETMVVTAS--AVE-QNLKDAPASIsVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDN-RKGVSIRGLDSSYTLILID 104

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1721521171 119 GL----PQAQHYHtlgsdaNGGAINEIEYENIRSIELSKGASSAEYGSGALGGAIGFRTKdaqdiiKEGQHW 186
Cdd:PRK10064  105 GKrvnsRNAVFRH------NDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITK------KIGQKW 164
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 612-725 6.30e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 50.14  E-value: 6.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 612 GVRFDQHrfksddpwtlSRTYRNWSWNGGITLKPTEFVSLSYRISNGFRVPAFYE------LYGKRDHIGLKDNEYVQRA 685
Cdd:PRK13528  444 GLRFDYH----------SEFGSNWSPSLNLSQELGDYFKVKAGIARAFKAPNLYQssegylLYSRGNGCPKDITSGGCYL 513

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1721521171 686 QRSHQLEPEKSTNHEIGVSFKGQFGYLDVSYFRNNYKNMI 725
Cdd:PRK13528  514 VGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKI 553
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
1-174 1.21e-05

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 49.24  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   1 MKYHHFRYSPVALTVLFALSHSYgAATENKKieenndlavlDEVIVTESHYAHERQNEVTGLgkVVKNYHEMSKNQILGI 80
Cdd:PRK13484    1 MKNKYIIAPGIAVMCSAVISSGY-ASSDKKE----------DTLVVTASGFTQQLRNAPASV--SVITSEQLQKKPVSDL 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  81 RDLTRYDPGISVveQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYhtlgSDANGGAINEIEY----ENIRSIELSKGAS 156
Cdd:PRK13484   68 VDAVKDVEGISI--TGGNEKPDISIRGLSGDYTLILVDGRRQSGRE----SRPNGSGGFEAGFippvEAIERIEVIRGPM 141

                         170
                  ....*....|....*...
gi 1721521171 157 SAEYGSGALGGAIGFRTK 174
Cdd:PRK13484  142 SSLYGSDAIGGVINIITK 159
PRK13513 PRK13513
ligand-gated channel protein;
5-209 2.15e-05

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 48.23  E-value: 2.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   5 HFRYSPVALTVLFALSHSYGAATENKKIEENNDLavldeVIVTESHYAHERQNEVTGLGKVvknyhemSKNQI--LGIRD 82
Cdd:PRK13513    4 RFRKTHKAALVIAAAISSQAYAAEKTNTATPTDT-----MVVTASGFQQRIQDAPASISVV-------TREQLenKAYRD 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  83 LT---RYDPGisVVEQGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDANGgaineIE------YENIRSIELSK 153
Cdd:PRK13513   72 VTdalKDVPG--VVVTGGGSTSDISIRGMAAKYTLILVDGKRVDTRSTRPNSDGSG-----IEqgwlppLAAIERIEVVR 144

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1721521171 154 GASSAEYGSGALGGAIGFRTKDAQDiikeGQHWGLDSKTSYA-SKNS--HFLQSIAAAG 209
Cdd:PRK13513  145 GPMSSLYGSDAMGGVINIITRKVQK----EWHGSLRADATLQeDSKSgdIFQTNAYASG 199
PRK13486 PRK13486
TonB-dependent receptor;
42-199 3.58e-05

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 47.71  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  42 DEVIVTESHYAHERQNEVTGLGkvVKNYHEMSKNQILGIRDLTRYDPGISVvEQGRGASSGY--AIRGVDKNRVSLLVDG 119
Cdd:PRK13486   26 DVMIVSASGYEKKLTNAAASVS--VISQEELQSSQYHDLAEALRSVEGVDV-ESGTGKTGGLeiSIRGMPASYTLILIDG 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171 120 LPQAQhyhtlGSDA--NGGAINEIEY----ENIRSIELSKGASSAEYGSGALGGAIGFRTKDAQDIIKEGQHWGLDSKTS 193
Cdd:PRK13486  103 VRQGG-----SSDVtpNGFSAMNTGFmpplAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVNAGLNLQES 177


                  ....*.
gi 1721521171 194 YASKNS 199
Cdd:PRK13486  178 NKWGNS 183
PRK13483 PRK13483
ligand-gated channel protein;
12-186 3.52e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 44.38  E-value: 3.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  12 ALTVLFALSHSYGAATENKKieenndlAVLDEVIVTESHYAHERQNEVTGLGkvVKNYHEMSKNQILGIRDLTRYDPGIS 91
Cdd:PRK13483   11 ALCLLPAVFVTHALAQAAPD-------KTMETVVVTASGYEQQIRDAPASIS--VITREDLENRFYRDLTDALLDVPGVV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  92 VVeqGRGASSGYAIRGVDKNRVSLLVDGLPQAQHYHTLGSDANGgaineIE------YENIRSIELSKGASSAEYGSGAL 165
Cdd:PRK13483   82 VT--GGGDRTDISLRGMGSQYTLILVDGKRQSSRETRPNSDGPG-----VEqawtppLAAIERIEVIRGPMSSLYGSDAI 154

                         170       180
                  ....*....|....*....|.
gi 1721521171 166 GGAIGFRTKdaqdiiKEGQHW 186
Cdd:PRK13483  155 GGVINIITR------KVPNEW 169
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 82-174 8.28e-04

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 43.21  E-value: 8.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  82 DLTRYDPGISVVeqGRGASSGYA------IRGVDKNRVSLLVDGLP----QAQHYHTLGSDANGGAINEIEYENIRSIEL 151
Cdd:PRK13528   72 DIIRKMPGVNLT--GNSASGTRGnnrqidIRGMGPENTLILIDGVPvtsrNSVRYSWRGERDTRGDTNWVPPEMVERIEV 149

                          90       100
                  ....*....|....*....|...
gi 1721521171 152 SKGASSAEYGSGALGGAIGFRTK 174
Cdd:PRK13528  150 IRGPAAARYGSGAAGGVVNIITK 172
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
7-178 1.06e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 42.71  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171   7 RYSPVALTVLFALSHSYGAATENKKIEENNDLAVLDEVIVTEshyahERQNeVTGLGKVVKNYHEMSKNQILG-IRDLTR 85
Cdd:PRK13524    4 KIHSLALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTA-----AEQN-LQAPGVSTITAEDIRKRPPANdVSEIIR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1721521171  86 YDPGISVVeqGRGASSGYA------IRGVDKNRVSLLVDGLP----QAQHYHTLGSDANGGAINEIEYENIRSIELSKGA 155
Cdd:PRK13524   78 TMPGVNLT--GNSTSGQRGnnrqidIRGMGPENTLILIDGKPvssrNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGP 155

                         170       180
                  ....*....|....*....|...
gi 1721521171 156 SSAEYGSGALGGAIGFRTKDAQD 178
Cdd:PRK13524  156 AAARYGNGAAGGVVNIITKKPTG 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH