|
Name |
Accession |
Description |
Interval |
E-value |
| SH3_10 |
pfam17902 |
SH3 domain; This entry represents an SH3 domain. |
386-450 |
4.75e-24 |
|
SH3 domain; This entry represents an SH3 domain.
Pssm-ID: 407754 Cd Length: 65 Bit Score: 96.95 E-value: 4.75e-24
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717023833 386 PLNLRRTRPSQSVTVDTICDWDSGDVQLSRGEKYTLKDNSNPENWVVQSKQGETKTVPAACFFIP 450
Cdd:pfam17902 1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
865-1669 |
2.22e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.88 E-value: 2.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 865 LNQLAFASKVLEKTEAVDGIPTVTQQNLRSENALRS-TRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKrpIER 943
Cdd:TIGR02168 222 LRELELALLVLRLEELREELEELQEELKEAEEELEElTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 944 LEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQID---RDPELDN 1020
Cdd:TIGR02168 300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEElesRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1021 QASRLSHDIKLLREENSSLSTELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAA-RTLQMQVDDEIFKRKSV 1099
Cdd:TIGR02168 380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERL 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1100 EENIIKLRNRTDELERLIDSVEPkvivkevkkveqdpELLKECAKLRTLIDEERRKSstlirelTELQTKYTVKEKQKPK 1179
Cdd:TIGR02168 460 EEALEELREELEEAEQALDAAER--------------ELAQLQARLDSLERLQENLE-------GFSEGVKALLKNQSGL 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1180 VEIKEVVHEIFQVDPETEKEIARLKREI--------QNASSKRTNYEKEVN---VTFTELNVVRSQKPTVEYKEDVQEVV 1248
Cdd:TIGR02168 519 SGILGVLSELISVDEGYEAAIEAALGGRlqavvvenLNAAKKAIAFLKQNElgrVTFLPLDSIKGTEIQGNDREILKNIE 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1249 KLEKSPEILREIDRLKQ-------QRNDIVTTSNRYQEQLTKLR-------VDRDEWKRERSkvetklVNKEVVKYENDP 1314
Cdd:TIGR02168 599 GFLGVAKDLVKFDPKLRkalsyllGGVLVVDDLDNALELAKKLRpgyrivtLDGDLVRPGGV------ITGGSAKTNSSI 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1315 L-LEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPeekvvvqevvllqkdpKLREEHNRLQTSFDEETSNRR 1393
Cdd:TIGR02168 673 LeRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE----------------QLRKELEELSRQISALRKDLA 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1394 QLEREVQQLRALVEDREKMLnfQEERDKKLAAEKELRQITLRIKEIEESPPAVQEKIvmeevvkiekdPVLEKSANTLRL 1473
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKEL--TELEAEIEELEERLEEAEEELAEAEAEIEELEAQI-----------EQLKEELKALRE 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1474 DLDKERSQFFNVQRECKNLQAKIDILQREKFMEKtiyKEVIRVEKDKILENERVrvrELYNKERNsrqDAEEEIRRLKDK 1553
Cdd:TIGR02168 804 ALDELRAELTLLNEEAANLRERLESLERRIAATE---RRLEDLEEQIEELSEDI---ESLAAEIE---ELEELIEELESE 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1554 IERAENTKRTwsreesdLQRARNLALQEKSSLENDLRELGRQKQQntvflskeselLTQRTEYDRQKRAQLGQELASLEG 1633
Cdd:TIGR02168 875 LEALLNERAS-------LEEALALLRSELEELSEELRELESKRSE-----------LRRELEELREKLAQLELRLEGLEV 936
|
810 820 830
....*....|....*....|....*....|....*.
gi 1717023833 1634 EILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:TIGR02168 937 RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1849-1887 |
5.19e-12 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 61.96 E-value: 5.19e-12
10 20 30
....*....|....*....|....*....|....*....
gi 1717023833 1849 LLEAQAATGGIIDIITKDRYSVHKAIDKGLIDNTNAQRL 1887
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
776-1562 |
1.63e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 70.00 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 776 KLQSQKRLVDEIQRKDPEKTSVVKLSQDIQSSLNDYEAEAERYRLTLdpsVSASAAKRQRIIPLQQNVEAQEKDLVKRyt 855
Cdd:pfam02463 259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKL---ERRKVDDEEKLKESEKEKKKAEKELKKE-- 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 856 EAAVENQQHLNQLAFASKVLEKTEAVDgiptVTQQNLRSENALRSTRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLL 935
Cdd:pfam02463 334 KEEIEELEKELKELEIKREAEEEEEEE----LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 936 KTKRPIERLEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRD 1015
Cdd:pfam02463 410 LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELL 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1016 PELDNQASRLSHDIKLLREENSSLS----TELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDD 1091
Cdd:pfam02463 490 LSRQKLEERSQKESKARSGLKVLLAlikdGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1092 EIFKRKSVEENIIKLR-NRTDELERLIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTKY 1170
Cdd:pfam02463 570 LTELPLGARKLRLLIPkLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1171 TVKEKQKPKVEIKEVvHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKL 1250
Cdd:pfam02463 650 KGVSLEEGLAEKSEV-KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ 728
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1251 EKSPEILREIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKyENDPLLEKEAEHLRQEVRNE 1330
Cdd:pfam02463 729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK-VEEEKEEKLKAQEEELRALE 807
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1331 SQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDRE 1410
Cdd:pfam02463 808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1411 KMLNFQEERDKKLAAEKELRQITLRIKEIEEsppaVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQFFNVQRECK 1490
Cdd:pfam02463 888 LESKEEKEKEEKKELEEESQKLNLLEEKENE----IEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717023833 1491 NLQAKIDILQREKFMEKTIYKEVirvekdkilenervrvRELYNKERNSRQDAEEEIRRLKDKIERAENTKR 1562
Cdd:pfam02463 964 RLLLAKEELGKVNLMAIEEFEEK----------------EERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1091-1661 |
8.81e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.93 E-value: 8.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1091 DEIFKRKSVEENIIKLRNRTDELERLIDSVEPKVIVKEVKKVEQDPELlKECAKLRTLIDEERRKSSTLIRELTEL---- 1166
Cdd:PRK03918 183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLeeki 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1167 -QTKYTVKEKQKPKVEIKEVVHEIFQVDPEtEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKED-V 1244
Cdd:PRK03918 262 rELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEErL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1245 QEVVKLEKspEILREIDRLKQqrndivttsnrYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENdplLEKEAEHLR 1324
Cdd:PRK03918 341 EELKKKLK--ELEKRLEELEE-----------RHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEE---LEKAKEEIE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1325 QEVRNESQRRREVEDVVYDLQNKYMLLERRK---PEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQ 1401
Cdd:PRK03918 405 EEISKITARIGELKKEIKELKKAIEELKKAKgkcPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1402 LRALVEDREKMLNFQEERDKKLAAEKELRQITLriKEIEESPPAVQEkiVMEEVVKIEKD-PVLEKSANTLRlDLDKERs 1480
Cdd:PRK03918 485 LEKVLKKESELIKLKELAEQLKELEEKLKKYNL--EELEKKAEEYEK--LKEKLIKLKGEiKSLKKELEKLE-ELKKKL- 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1481 qffnvqrecKNLQAKIDILQREKfmeKTIYKEVIRVEKDKILE-NERVRVRELYNKERNSRQDAEEEIRRLKDKIEraen 1559
Cdd:PRK03918 559 ---------AELEKKLDELEEEL---AELLKELEELGFESVEElEERLKELEPFYNEYLELKDAEKELEREEKELK---- 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1560 tkrtwsREESDLQRARnlalQEKSSLENDLRELGRQKQQNTVFLSKEselltqRTEYDRQKRAQLGQELASLEGEILKEK 1639
Cdd:PRK03918 623 ------KLEEELDKAF----EELAETEKRLEELRKELEELEKKYSEE------EYEELREEYLELSRELAGLRAELEELE 686
|
570 580
....*....|....*....|..
gi 1717023833 1640 DQIYEKERTIRELqsKANREEI 1661
Cdd:PRK03918 687 KRREEIKKTLEKL--KEELEER 706
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1095-1669 |
7.92e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1095 KRKSVEENIIKLRNRTDELERLIDSVEpkvivkevkkveqdpellKECAKL---RTLIDEERRKSSTL-IRELTELQTKY 1170
Cdd:COG1196 180 KLEATEENLERLEDILGELERQLEPLE------------------RQAEKAeryRELKEELKELEAELlLLKLRELEAEL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1171 TVKEKQKPKVEIKEVvheifqvdpETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKL 1250
Cdd:COG1196 242 EELEAELEELEAELE---------ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1251 EKSPEILR---EIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVvkyENDPLLEKEAEHLRQEV 1327
Cdd:COG1196 313 ELEERLEEleeELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA---ELAEAEEELEELAEELL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1328 RNESQRRREVEDVVYDLQNKYMLLERRkpeEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQLRA-LV 1406
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLElLA 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1407 EDREKMLNFQEERDKKLAAEKELRQITLRIKEIEESPPAvQEKIVMEEVVKIEKDPVL---------EKSANTLRLDLDK 1477
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAgavavligvEAAYEAALEAALA 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1478 ERSQFFNVQREcKNLQAKIDILQREKFMEKTIY-KEVIRVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKDKIE- 1555
Cdd:COG1196 546 AALQNIVVEDD-EVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLg 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1556 --RAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEG 1633
Cdd:COG1196 625 rtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704
|
570 580 590
....*....|....*....|....*....|....*.
gi 1717023833 1634 EILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:COG1196 705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1885-1922 |
1.45e-08 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 52.10 E-value: 1.45e-08
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1885 QRLLNAQKAFTGVEDPVTKKRLSVGEAMQKGWMTKETA 1922
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1925-1963 |
3.95e-08 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 50.79 E-value: 3.95e-08
10 20 30
....*....|....*....|....*....|....*....
gi 1717023833 1925 YLEVQHLTGGLIDPKKTGRIPVSDAVVTHMLDDSTAKKL 1963
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
213-388 |
2.28e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 53.60 E-value: 2.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 213 LYNHLHGCTKELVYLNDQQSKILKQNWSDQMQDSTDVRRQYENFKtNDLLSQEEFVNNLQDDGVRMIELKHPAVESIQTH 292
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALE-AELAAHEERVEALNELGEQLIEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 293 QDALKNEWQNFLNLCICQESHLKNVENYKKFQEDADAVSQTLKKVNSNLDTNYSKDATGATSDLLGLLEKDEKTLNQAEK 372
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170
....*....|....*.
gi 1717023833 373 DIESLKQRSLEIPPLN 388
Cdd:cd00176 161 RLKSLNELAEELLEEG 176
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1678-1706 |
1.46e-05 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 43.47 E-value: 1.46e-05
10 20
....*....|....*....|....*....
gi 1717023833 1678 ILDPDTGMDMSPYEAYRRGIIDRNQYIQL 1706
Cdd:pfam00681 11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1848-1880 |
1.56e-05 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 43.62 E-value: 1.56e-05
10 20 30
....*....|....*....|....*....|...
gi 1717023833 1848 KLLEAQAATGGIIDIITKDRYSVHKAIDKGLID 1880
Cdd:smart00250 2 RLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
214-315 |
2.34e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 42.32 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 214 YNHLHGCTKELVYLNDQQSKILKQNWSDqmqDSTDVRRQYENFKT--NDLLSQEEFVNNLQDDGVRMIELKHPAVESIQT 291
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGK---DLESVEALLKKHEAfeAELEAHEERVEALNELGEQLIEEGHPDAEEIEE 77
|
90 100
....*....|....*....|....
gi 1717023833 292 HQDALKNEWQNFLNLCICQESHLK 315
Cdd:smart00150 78 RLEELNERWEELKELAEERRQKLE 101
|
|
| SH3_Tec_like |
cd11768 |
Src Homology 3 domain of Tec-like Protein Tyrosine Kinases; The Tec (Tyrosine kinase expressed ... |
407-444 |
9.97e-04 |
|
Src Homology 3 domain of Tec-like Protein Tyrosine Kinases; The Tec (Tyrosine kinase expressed in hepatocellular carcinoma) subfamily is composed of Tec, Btk, Bmx (Etk), Itk (Tsk, Emt), Rlk (Txk), and similar proteins. They are cytoplasmic (or nonreceptor) tyr kinases containing Src homology protein interaction domains (SH3, SH2) N-terminal to the catalytic tyr kinase domain. Most Tec subfamily members (except Rlk) also contain an N-terminal pleckstrin homology (PH) domain, which binds the products of PI3K and allows membrane recruitment and activation. In addition, some members contain the Tec homology (TH) domain, which contains proline-rich and zinc-binding regions. Tec kinases are expressed mainly by haematopoietic cells, although Tec and Bmx are also found in endothelial cells. B-cells express Btk and Tec, while T-cells express Itk, Txk, and Tec. Collectively, Tec kinases are expressed in a variety of myeloid cells such as mast cells, platelets, macrophages, and dendritic cells. Each Tec kinase shows a distinct cell-type pattern of expression. The function of Tec kinases in lymphoid cells have been studied extensively. They play important roles in the development, differentiation, maturation, regulation, survival, and function of B-cells and T-cells. SH3 domains are protein interaction domains that bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs. They play versatile and diverse roles in the cell including the regulation of enzymes, changing the subcellular localization of signaling pathway components, and mediating the formation of multiprotein complex assemblies.
Pssm-ID: 212702 [Multi-domain] Cd Length: 54 Bit Score: 38.79 E-value: 9.97e-04
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 407 DSGDVQLSRGEKYTLKDNSNPENWVVQSKQGETKTVPA 444
Cdd:cd11768 12 EPGDLPLEKGEEYVVLDDSNEHWWRARDKNGNEGYIPS 49
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1678-1703 |
2.41e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 37.46 E-value: 2.41e-03
|
| PLEC |
smart00250 |
Plectin repeat; |
1923-1960 |
6.15e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 36.31 E-value: 6.15e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1923 LPYLEVQHLTGGLIDPKKTGRIPVSDAVVTHMLDDSTA 1960
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1809-1846 |
8.77e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 35.92 E-value: 8.77e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1809 KNFYDDSFPIAGIYDDTTGIKCTIRNAVAKNMVDPITA 1846
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SH3_10 |
pfam17902 |
SH3 domain; This entry represents an SH3 domain. |
386-450 |
4.75e-24 |
|
SH3 domain; This entry represents an SH3 domain.
Pssm-ID: 407754 Cd Length: 65 Bit Score: 96.95 E-value: 4.75e-24
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717023833 386 PLNLRRTRPSQSVTVDTICDWDSGDVQLSRGEKYTLKDNSNPENWVVQSKQGETKTVPAACFFIP 450
Cdd:pfam17902 1 PLKQRRSPVTRPIPVKALCDYKQGEVTVEKGEECTLLDNSDREKWKVQTSSGVEKLVPSVCFLIP 65
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
865-1669 |
2.22e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 85.88 E-value: 2.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 865 LNQLAFASKVLEKTEAVDGIPTVTQQNLRSENALRS-TRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKrpIER 943
Cdd:TIGR02168 222 LRELELALLVLRLEELREELEELQEELKEAEEELEElTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE--ISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 944 LEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQID---RDPELDN 1020
Cdd:TIGR02168 300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEElesRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1021 QASRLSHDIKLLREENSSLSTELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAA-RTLQMQVDDEIFKRKSV 1099
Cdd:TIGR02168 380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERL 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1100 EENIIKLRNRTDELERLIDSVEPkvivkevkkveqdpELLKECAKLRTLIDEERRKSstlirelTELQTKYTVKEKQKPK 1179
Cdd:TIGR02168 460 EEALEELREELEEAEQALDAAER--------------ELAQLQARLDSLERLQENLE-------GFSEGVKALLKNQSGL 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1180 VEIKEVVHEIFQVDPETEKEIARLKREI--------QNASSKRTNYEKEVN---VTFTELNVVRSQKPTVEYKEDVQEVV 1248
Cdd:TIGR02168 519 SGILGVLSELISVDEGYEAAIEAALGGRlqavvvenLNAAKKAIAFLKQNElgrVTFLPLDSIKGTEIQGNDREILKNIE 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1249 KLEKSPEILREIDRLKQ-------QRNDIVTTSNRYQEQLTKLR-------VDRDEWKRERSkvetklVNKEVVKYENDP 1314
Cdd:TIGR02168 599 GFLGVAKDLVKFDPKLRkalsyllGGVLVVDDLDNALELAKKLRpgyrivtLDGDLVRPGGV------ITGGSAKTNSSI 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1315 L-LEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPeekvvvqevvllqkdpKLREEHNRLQTSFDEETSNRR 1393
Cdd:TIGR02168 673 LeRRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELE----------------QLRKELEELSRQISALRKDLA 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1394 QLEREVQQLRALVEDREKMLnfQEERDKKLAAEKELRQITLRIKEIEESPPAVQEKIvmeevvkiekdPVLEKSANTLRL 1473
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKEL--TELEAEIEELEERLEEAEEELAEAEAEIEELEAQI-----------EQLKEELKALRE 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1474 DLDKERSQFFNVQRECKNLQAKIDILQREKFMEKtiyKEVIRVEKDKILENERVrvrELYNKERNsrqDAEEEIRRLKDK 1553
Cdd:TIGR02168 804 ALDELRAELTLLNEEAANLRERLESLERRIAATE---RRLEDLEEQIEELSEDI---ESLAAEIE---ELEELIEELESE 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1554 IERAENTKRTwsreesdLQRARNLALQEKSSLENDLRELGRQKQQntvflskeselLTQRTEYDRQKRAQLGQELASLEG 1633
Cdd:TIGR02168 875 LEALLNERAS-------LEEALALLRSELEELSEELRELESKRSE-----------LRRELEELREKLAQLELRLEGLEV 936
|
810 820 830
....*....|....*....|....*....|....*.
gi 1717023833 1634 EILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:TIGR02168 937 RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1849-1887 |
5.19e-12 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 61.96 E-value: 5.19e-12
10 20 30
....*....|....*....|....*....|....*....
gi 1717023833 1849 LLEAQAATGGIIDIITKDRYSVHKAIDKGLIDNTNAQRL 1887
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1137-1680 |
1.48e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.09 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1137 ELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEikEVVHEIFQVDPETEKEIARLKREIQNASSKRTN 1216
Cdd:TIGR02168 236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE--EEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1217 YEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKLEKSPEILR---EIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKR 1293
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESleaELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1294 ERSKVETKLVNkevvkyendplLEKEAEHLRQEVRNESQRRREVEDVVYDLQnkymLLERRKPEEKVVVQEVVLLQKDPK 1373
Cdd:TIGR02168 394 QIASLNNEIER-----------LEARLERLEDRRERLQQEIEELLKKLEEAE----LKELQAELEELEEELEELQEELER 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1374 LREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLN----FQEERDKKLAAEKELRQITLRIKEIEESPP----A 1445
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEnlegFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1446 VQ-------EKIVMEEVVKIEKDPVLEKSANTLR-----LDLDKER----SQFFNVQRECKNLQAKIDILQREKFMEKTI 1509
Cdd:TIGR02168 539 IEaalggrlQAVVVENLNAAKKAIAFLKQNELGRvtflpLDSIKGTeiqgNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1510 ------------YKEVIRVEKDK-------ILENERVRVRELY----NKERNSRQDAEEEIRRLKDKIERAENtkrtwsr 1566
Cdd:TIGR02168 619 syllggvlvvddLDNALELAKKLrpgyrivTLDGDLVRPGGVItggsAKTNSSILERRREIEELEEKIEELEE------- 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1567 EESDLQRARNLALQEKSSLENDLREL---GRQKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEGEILKEKDQIY 1643
Cdd:TIGR02168 692 KIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771
|
570 580 590
....*....|....*....|....*....|....*..
gi 1717023833 1644 EKERTIRELqsKANREEINQETQLRETNVSTKISILD 1680
Cdd:TIGR02168 772 EAEEELAEA--EAEIEELEAQIEQLKEELKALREALD 806
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
776-1562 |
1.63e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 70.00 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 776 KLQSQKRLVDEIQRKDPEKTSVVKLSQDIQSSLNDYEAEAERYRLTLdpsVSASAAKRQRIIPLQQNVEAQEKDLVKRyt 855
Cdd:pfam02463 259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKL---ERRKVDDEEKLKESEKEKKKAEKELKKE-- 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 856 EAAVENQQHLNQLAFASKVLEKTEAVDgiptVTQQNLRSENALRSTRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLL 935
Cdd:pfam02463 334 KEEIEELEKELKELEIKREAEEEEEEE----LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 936 KTKRPIERLEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRD 1015
Cdd:pfam02463 410 LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELL 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1016 PELDNQASRLSHDIKLLREENSSLS----TELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDD 1091
Cdd:pfam02463 490 LSRQKLEERSQKESKARSGLKVLLAlikdGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1092 EIFKRKSVEENIIKLR-NRTDELERLIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTKY 1170
Cdd:pfam02463 570 LTELPLGARKLRLLIPkLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1171 TVKEKQKPKVEIKEVvHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKL 1250
Cdd:pfam02463 650 KGVSLEEGLAEKSEV-KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ 728
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1251 EKSPEILREIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKyENDPLLEKEAEHLRQEVRNE 1330
Cdd:pfam02463 729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK-VEEEKEEKLKAQEEELRALE 807
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1331 SQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDRE 1410
Cdd:pfam02463 808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1411 KMLNFQEERDKKLAAEKELRQITLRIKEIEEsppaVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQFFNVQRECK 1490
Cdd:pfam02463 888 LESKEEKEKEEKKELEEESQKLNLLEEKENE----IEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717023833 1491 NLQAKIDILQREKFMEKTIYKEVirvekdkilenervrvRELYNKERNSRQDAEEEIRRLKDKIERAENTKR 1562
Cdd:pfam02463 964 RLLLAKEELGKVNLMAIEEFEEK----------------EERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
892-1621 |
3.90e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.47 E-value: 3.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 892 LRSENALRstRDTEALQSQLKEEQDKVAEVQRTLEE-----HRTQLLLLKTKRPIERLEEKEVVQYYRD--------PKL 958
Cdd:TIGR02169 229 LKEKEALE--RQKEAIERQLASLEEELEKLTEEISElekrlEEIEQLLEELNKKIKDLGEEEQLRVKEKigeleaeiASL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 959 ESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQL--LTKEVTQI-DRDPELDNQASRLSHDIKLLREE 1035
Cdd:TIGR02169 307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRdkLTEEYAELkEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1036 NSSLSTELERLKREVLILEQKQPNIKEKvvvkevvklerdpemvkaARTLQMQVDDEIFKRKSVEENIIKLRNRTDELER 1115
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEE------------------LQRLSEELADLNAAIAGIEAKINELEEEKEDKAL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1116 LIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEIKE--------VVH 1187
Cdd:TIGR02169 449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKasiqgvhgTVA 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1188 EIFQVDPETEKEI-----ARLKR---EIQNASSKRTNYEKEVNV---TFTELNVVRS-QKPT---------------VEY 1240
Cdd:TIGR02169 529 QLGSVGERYATAIevaagNRLNNvvvEDDAVAKEAIELLKRRKAgraTFLPLNKMRDeRRDLsilsedgvigfavdlVEF 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1241 KEDVQEVVK-------------------------------------------------------LEKSPEILREIDRLKQ 1265
Cdd:TIGR02169 609 DPKYEPAFKyvfgdtlvvedieaarrlmgkyrmvtlegelfeksgamtggsraprggilfsrsePAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1266 QRNDIvttsnryQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQ 1345
Cdd:TIGR02169 689 ELSSL-------QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK 761
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1346 NkymlLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEetsnRRQLEREVQQLRALVEDREKMLNfqEERDKKLAA 1425
Cdd:TIGR02169 762 E----LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAE----LSKLEEEVSRIEARLREIEQKLN--RLTLEKEYL 831
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1426 EKELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVLEKSANTLRlDLDKERSqffNVQRECKNLQAKIDILQREK-F 1504
Cdd:TIGR02169 832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR-DLESRLG---DLKKERDELEAQLRELERKIeE 907
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1505 MEKTIYKEVIRVEKDKI-LENERVRVRELynkERNSRQDAEE-----EIRRLKDKIERAEntkrtwsREESDLQRARNLA 1578
Cdd:TIGR02169 908 LEAQIEKKRKRLSELKAkLEALEEELSEI---EDPKGEDEEIpeeelSLEDVQAELQRVE-------EEIRALEPVNMLA 977
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 1717023833 1579 LQEKSSLENDLRELgrQKQQNTvfLSKESELLTQRTE-YDRQKR 1621
Cdd:TIGR02169 978 IQEYEEVLKRLDEL--KEKRAK--LEEERKAILERIEeYEKKKR 1017
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1091-1661 |
8.81e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.93 E-value: 8.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1091 DEIFKRKSVEENIIKLRNRTDELERLIDSVEPKVIVKEVKKVEQDPELlKECAKLRTLIDEERRKSSTLIRELTEL---- 1166
Cdd:PRK03918 183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLeeki 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1167 -QTKYTVKEKQKPKVEIKEVVHEIFQVDPEtEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKED-V 1244
Cdd:PRK03918 262 rELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEErL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1245 QEVVKLEKspEILREIDRLKQqrndivttsnrYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENdplLEKEAEHLR 1324
Cdd:PRK03918 341 EELKKKLK--ELEKRLEELEE-----------RHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEE---LEKAKEEIE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1325 QEVRNESQRRREVEDVVYDLQNKYMLLERRK---PEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQ 1401
Cdd:PRK03918 405 EEISKITARIGELKKEIKELKKAIEELKKAKgkcPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1402 LRALVEDREKMLNFQEERDKKLAAEKELRQITLriKEIEESPPAVQEkiVMEEVVKIEKD-PVLEKSANTLRlDLDKERs 1480
Cdd:PRK03918 485 LEKVLKKESELIKLKELAEQLKELEEKLKKYNL--EELEKKAEEYEK--LKEKLIKLKGEiKSLKKELEKLE-ELKKKL- 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1481 qffnvqrecKNLQAKIDILQREKfmeKTIYKEVIRVEKDKILE-NERVRVRELYNKERNSRQDAEEEIRRLKDKIEraen 1559
Cdd:PRK03918 559 ---------AELEKKLDELEEEL---AELLKELEELGFESVEElEERLKELEPFYNEYLELKDAEKELEREEKELK---- 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1560 tkrtwsREESDLQRARnlalQEKSSLENDLRELGRQKQQNTVFLSKEselltqRTEYDRQKRAQLGQELASLEGEILKEK 1639
Cdd:PRK03918 623 ------KLEEELDKAF----EELAETEKRLEELRKELEELEKKYSEE------EYEELREEYLELSRELAGLRAELEELE 686
|
570 580
....*....|....*....|..
gi 1717023833 1640 DQIYEKERTIRELqsKANREEI 1661
Cdd:PRK03918 687 KRREEIKKTLEKL--KEELEER 706
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
910-1682 |
7.32e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.14 E-value: 7.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 910 QLKEEQDKVAEVQRTLEEHRTQLLLLKTKRPIERLEEKEVVQYYRdpKLESSVSALKNQVENEYRQREITQSEiegVNKK 989
Cdd:pfam02463 170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQ--LKEKLELEEEYLLYLDYLKLNEERID---LLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 990 IIQIDSQRKTIKPQLLTKEVTQIDRDPELDNQASRLshdIKLLREENSSLSTELERLKREVLILEQKQpnikeKVVVKEV 1069
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE---KKLQEEELKLLAKEEEELKSELLKLERRK-----VDDEEKL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1070 VKLERDPEMVKAARTLQMQVDDEIFK-RKSVEENIIKLRNRTDELERLIDSVEpKVIVKEVKKVEQDPELLKECAKLRTL 1148
Cdd:pfam02463 317 KESEKEKKKAEKELKKEKEEIEELEKeLKELEIKREAEEEEEEELEKLQEKLE-QLEEELLAKKKLESERLSSAAKLKEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1149 IDEERRKSSTLIRELTEL--QTKYTVKEKQKPKVEIKEVVHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNVTFT 1226
Cdd:pfam02463 396 ELELKSEEEKEAQLLLELarQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1227 ELNVVRSQKPTVEYKEDVQEVVKLEKSPEILREIDRLK-QQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNK 1305
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLaLIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1306 EVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSF 1385
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1386 DEETSNRRQLEREVQQLRALVEDREKM-LNFQEERDKKLAAEKELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVL 1464
Cdd:pfam02463 636 KLKESAKAKESGLRKGVSLEEGLAEKSeVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1465 EKSANTLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFMEKTIYKEvirVEKDKILENERVRVRELYNKERNSRQDAE 1544
Cdd:pfam02463 716 KLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE---EEKSELSLKEKELAEEREKTEKLKVEEEK 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1545 EEIRRLKDKIERAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQQN-TVFLSKESELLTQRTEYDRQKRAQ 1623
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKlEKLAEEELERLEEEITKEELLQEL 872
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 1717023833 1624 LGQELASLEGEILKEKDQIYEKERTIRELQSKANREEINQETQLRETNVSTKISILDPD 1682
Cdd:pfam02463 873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL 931
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1095-1669 |
7.92e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.11 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1095 KRKSVEENIIKLRNRTDELERLIDSVEpkvivkevkkveqdpellKECAKL---RTLIDEERRKSSTL-IRELTELQTKY 1170
Cdd:COG1196 180 KLEATEENLERLEDILGELERQLEPLE------------------RQAEKAeryRELKEELKELEAELlLLKLRELEAEL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1171 TVKEKQKPKVEIKEVvheifqvdpETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKL 1250
Cdd:COG1196 242 EELEAELEELEAELE---------ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1251 EKSPEILR---EIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVvkyENDPLLEKEAEHLRQEV 1327
Cdd:COG1196 313 ELEERLEEleeELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA---ELAEAEEELEELAEELL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1328 RNESQRRREVEDVVYDLQNKYMLLERRkpeEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQLRA-LV 1406
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLElLA 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1407 EDREKMLNFQEERDKKLAAEKELRQITLRIKEIEESPPAvQEKIVMEEVVKIEKDPVL---------EKSANTLRLDLDK 1477
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAgavavligvEAAYEAALEAALA 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1478 ERSQFFNVQREcKNLQAKIDILQREKFMEKTIY-KEVIRVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKDKIE- 1555
Cdd:COG1196 546 AALQNIVVEDD-EVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLg 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1556 --RAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEG 1633
Cdd:COG1196 625 rtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704
|
570 580 590
....*....|....*....|....*....|....*.
gi 1717023833 1634 EILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:COG1196 705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
905-1651 |
1.01e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 60.90 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 905 EALQSQLKEEQDKVAEVQRTLEEH-----------RTQLLLLKTKRPIERLEEKEVVQYYRdpKLESSVSALKNQVENEY 973
Cdd:pfam15921 74 EHIERVLEEYSHQVKDLQRRLNESnelhekqkfylRQSVIDLQTKLQEMQMERDAMADIRR--RESQSQEDLRNQLQNTV 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 974 RQREITQSEIEG-VNKKIIQIDSQRKT-IKPQLLTKEVTQIDRDPELDNQASRLSHD---IKLLREENSSLSTELERLKR 1048
Cdd:pfam15921 152 HELEAAKCLKEDmLEDSNTQIEQLRKMmLSHEGVLQEIRSILVDFEEASGKKIYEHDsmsTMHFRSLGSAISKILRELDT 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1049 EVLILEQKQpnikekvvvkevvklerdpemvkaartlqMQVDDEIFKRKSVEENIIKL--RNRTDELERLIDSVEPKVIV 1126
Cdd:pfam15921 232 EISYLKGRI-----------------------------FPVEDQLEALKSESQNKIELllQQHQDRIEQLISEHEVEITG 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1127 KEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTkyTVKEKQKPKVEIKEVVHEIFQvdpETEKEIARLKRE 1206
Cdd:pfam15921 283 LTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLES--TVSQLRSELREAKRMYEDKIE---ELEKQLVLANSE 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1207 IQNASSKRTNYEKEVNVTFTEL-----NVVRSQKPTVEYKEDVQEVVKLEKSPEIlrEIDRLKQQRNDIVTTSNRYQEQL 1281
Cdd:pfam15921 358 LTEARTERDQFSQESGNLDDQLqkllaDLHKREKELSLEKEQNKRLWDRDTGNSI--TIDHLRRELDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1282 TKLRVD-RDEWKRERSKVETKlvNKEVVKYEN-DPLLEKEAEHLRQevrnesqrrrevedVVYDLQNKYMLLERRKPEEK 1359
Cdd:pfam15921 436 KAMKSEcQGQMERQMAAIQGK--NESLEKVSSlTAQLESTKEMLRK--------------VVEELTAKKMTLESSERTVS 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1360 VVVQevvllqkdpKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDK-KLAAEKELRQITLRIKE 1438
Cdd:pfam15921 500 DLTA---------SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEAlKLQMAEKDKVIEILRQQ 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1439 IEESPPAVQEKIVMEEVVKIEKdPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFMEKTIYKEVIRVEK 1518
Cdd:pfam15921 571 IENMTQLVGQHGRTAGAMQVEK-AQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK 649
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1519 DKILENERV--RVRELYNKERNSRQDAEEEIRRLKDKIERAENT----KRTWSREESDLQRARN-LALQEKSSLENDLRE 1591
Cdd:pfam15921 650 DIKQERDQLlnEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnklKMQLKSAQSELEQTRNtLKSMEGSDGHAMKVA 729
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1717023833 1592 LGRQKQ-----------QNTV-FLSKESELLTQRTEYDRQKRAQLGQELASLEGEILK---EKDQIYEKERTIRE 1651
Cdd:pfam15921 730 MGMQKQitakrgqidalQSKIqFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagELEVLRSQERRLKE 804
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1885-1922 |
1.45e-08 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 52.10 E-value: 1.45e-08
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1885 QRLLNAQKAFTGVEDPVTKKRLSVGEAMQKGWMTKETA 1922
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
907-1569 |
2.34e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 59.26 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 907 LQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTK-----RPIERLEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQS 981
Cdd:TIGR04523 45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKikileQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEV 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 982 EIEGVNKKIIQIDSQRKTIKPQLLTKEvtqidrdpeldNQASRLSHDIKLLREENSSLSTELERLKREVLILEQKQPNIK 1061
Cdd:TIGR04523 125 ELNKLEKQKKENKKNIDKFLTEIKKKE-----------KELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1062 EKVVVKEVVKLERDpEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERLIDSVEpkviVKEVKKVEQDPELLKE 1141
Cdd:TIGR04523 194 NKLLKLELLLSNLK-KKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQ----TQLNQLKDEQNKIKKQ 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1142 CAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEIKEVVHEIFQVD----------PETEKEIARLKREIQNAS 1211
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEkkleeiqnqiSQNNKIISQLNEQISQLK 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1212 SKRTNYEKEvnvtftelnvvrSQKPTVEYKEDVQEVVKLEKSPE-ILREIDRLKQQRNDIVTTSNRYQEQLTKLRvdrde 1290
Cdd:TIGR04523 349 KELTNSESE------------NSEKQRELEEKQNEIEKLKKENQsYKQEIKNLESQINDLESKIQNQEKLNQQKD----- 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1291 wkrerSKVETKLVNKEvvkyendpLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQK 1370
Cdd:TIGR04523 412 -----EQIKKLQQEKE--------LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1371 dpKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEK-----ELRQITLRIKEIEESPPA 1445
Cdd:TIGR04523 479 --KIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekesKISDLEDELNKDDFELKK 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1446 VQ-EKIVMEEVVKIEK----DPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFMEKTIYKEVIRVEKD- 1519
Cdd:TIGR04523 557 ENlEKEIDEKNKEIEElkqtQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNi 636
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 1717023833 1520 ----KILENERVRVRELYNKERNSRQDAEEEIRRLKDKIERAENTKRTWSREES 1569
Cdd:TIGR04523 637 kskkNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELS 690
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1925-1963 |
3.95e-08 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 50.79 E-value: 3.95e-08
10 20 30
....*....|....*....|....*....|....*....
gi 1717023833 1925 YLEVQHLTGGLIDPKKTGRIPVSDAVVTHMLDDSTAKKL 1963
Cdd:pfam00681 1 LLEAQAATGGIIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
902-1669 |
5.09e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 5.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 902 RDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKRpierlEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQS 981
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRER-----EKAERYQALLKEKREYEGYELLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 982 EIEGVNKKIIQIDSQRktikpQLLTKEVTQIDRD-PELDNQASRLSHDIKL-LREENSSLSTELERLKRevlILEQKQPN 1059
Cdd:TIGR02169 245 QLASLEEELEKLTEEI-----SELEKRLEEIEQLlEELNKKIKDLGEEEQLrVKEKIGELEAEIASLER---SIAEKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1060 IKEKVVVKEVVKLERDpEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERLIDSVEpkvivkevkkveqdpell 1139
Cdd:TIGR02169 317 LEDAEERLAKLEAEID-KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD------------------ 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1140 KECAKLRTLIDEERRKSSTLIRELTELQTkyTVKEKQKPKVEIKEVVHEIfqvdpetEKEIARLKREIQNASSKRTNYEK 1219
Cdd:TIGR02169 378 KEFAETRDELKDYREKLEKLKREINELKR--ELDRLQEELQRLSEELADL-------NAAIAGIEAKINELEEEKEDKAL 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1220 EVNVTFTELNVVRSQKPTV--EYKEDVQEVVKLEKSPEIL-REIDRLKQQRNDIVTTSNRYQEQLTKLRVDRD------- 1289
Cdd:TIGR02169 449 EIKKQEWKLEQLAADLSKYeqELYDLKEEYDRVEKELSKLqRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtva 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1290 ---EWKRERSK--------------VETKLVNKEVVKYendpLLEKEA--------EHLRQEVRNESQRRRE-VEDVVYD 1343
Cdd:TIGR02169 529 qlgSVGERYATaievaagnrlnnvvVEDDAVAKEAIEL----LKRRKAgratflplNKMRDERRDLSILSEDgVIGFAVD 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1344 L---QNKY----------MLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETS---NRRQLEREVQQLRALVE 1407
Cdd:TIGR02169 605 LvefDPKYepafkyvfgdTLVVEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGgilFSRSEPAELQRLRERLE 684
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1408 DREKMLNF-QEERDKklaAEKELRQITLRIKEIEEsppavqekivmeEVVKIEKDpvleksantlRLDLDKERSQFfnvQ 1486
Cdd:TIGR02169 685 GLKRELSSlQSELRR---IENRLDELSQELSDASR------------KIGEIEKE----------IEQLEQEEEKL---K 736
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1487 RECKNLQAKIDILQREKFMEKTIYKEVIRV--EKDKILENERVRVRELYNKERNSR-QDAEEEIRRLKDKIERAENTKRT 1563
Cdd:TIGR02169 737 ERLEELEEDLSSLEQEIENVKSELKELEARieELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLRE 816
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1564 WSREESDLQRARNLALQEKSSLENDLRELGRQKqqntvflskeselltqrteydrqkrAQLGQELASLEGEILKEKDQIY 1643
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI-------------------------KSIEKEIENLNGKKEELEEELE 871
|
810 820
....*....|....*....|....*....
gi 1717023833 1644 EKERTIRELQSKA---NREEINQETQLRE 1669
Cdd:TIGR02169 872 ELEAALRDLESRLgdlKKERDELEAQLRE 900
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1151-1667 |
5.55e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.61 E-value: 5.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1151 EERRKSSTLIRELTELQTKytvKEKQKPKVEIKEVVHEIFQVDPETEKEIARLKREIQNASSKRTNYEK----EVNVTFT 1226
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKK---ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadAAKKKAE 1388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1227 ELNVVRSQKPTVEykEDVQEVVKLEKSPEILREIDRLKQQRNDIvttsnRYQEQLTKLRVDRDEWKRERSKVETKLVNKE 1306
Cdd:PTZ00121 1389 EKKKADEAKKKAE--EDKKKADELKKAAAAKKKADEAKKKAEEK-----KKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1307 VVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFD 1386
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK 1541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1387 EETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEK--ELRQI-TLRIKEI------------EESPPAVQEKIV 1451
Cdd:PTZ00121 1542 AEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKaeEAKKAeEARIEEVmklyeeekkmkaEEAKKAEEAKIK 1621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1452 MEEVVKIEKDpvlEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFMEKTiykeviRVEKDKILENERVRVRE 1531
Cdd:PTZ00121 1622 AEELKKAEEE---KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKK------KAEEAKKAEEDEKKAAE 1692
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1532 LYNKERNSRQDAEEEIRRLKDKIERAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQqntvflskeselLT 1611
Cdd:PTZ00121 1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK------------IA 1760
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1717023833 1612 QRTEYDRQKRAQLGQELASLEGEILKEKDQI--YEKERTIRELQSK-ANREEINQETQL 1667
Cdd:PTZ00121 1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKrrMEVDKKIKDIFDNfANIIEGGKEGNL 1819
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1374-1661 |
8.27e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 57.62 E-value: 8.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1374 LREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEKELRQITLRIKEIEESPPAVQEkivme 1453
Cdd:COG4913 615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA----- 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1454 evvkiekdpvLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIdilqrekfmektiykevirvekdkilenervrvrely 1533
Cdd:COG4913 690 ----------LEEQLEELEAELEELEEELDELKGEIGRLEKEL------------------------------------- 722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1534 nkernsrQDAEEEIRRLKDKIERAENTKRTWSREESDLQRA----RNLALQEKSSLENDLRELGRQKQQntvflsKESEL 1609
Cdd:COG4913 723 -------EQAEEELDELQDRLEAAEDLARLELRALLEERFAaalgDAVERELRENLEERIDALRARLNR------AEEEL 789
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1717023833 1610 LTQRTEYDRQ---KRAQLGQELASLEG--EILK--EKDQIYEKERTIRELQSKANREEI 1661
Cdd:COG4913 790 ERAMRAFNREwpaETADLDADLESLPEylALLDrlEEDGLPEYEERFKELLNENSIEFV 848
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1137-1416 |
1.29e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.06 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1137 ELLKECAKLRTLIDEERRKSSTLIRELT----------ELQTKYTVKEKQKPKVEIKEVVHEIFQVDPETEKEIARLKRE 1206
Cdd:pfam17380 307 EKAREVERRRKLEEAEKARQAEMDRQAAiyaeqermamERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQME 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1207 IQNaSSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEdvQEVVKLEKSPEILREIDRLKQQR----NDIVTTSNRYQEQLT 1282
Cdd:pfam17380 387 RQQ-KNERVRQELEAARKVKILEEERQRKIQQQKVE--MEQIRAEQEEARQREVRRLEEERaremERVRLEEQERQQQVE 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1283 KLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKpeekvvv 1362
Cdd:pfam17380 464 RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR------- 536
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1717023833 1363 qEVVLLQKDPKLREEHNRLQTSF---DEETSNRRQLEREVQQLRALVEDREKMLNFQ 1416
Cdd:pfam17380 537 -EAEEERRKQQEMEERRRIQEQMrkaTEERSRLEAMEREREMMRQIVESEKARAEYE 592
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1021-1635 |
1.36e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1021 QASRLSHDIKLLREENSSLSTELERLKREVLILEQKQpnikekvvvkevVKLErdpemvKAARTLQMQVDDEifkRKSVE 1100
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEAEL------------AELE------AELEELRLELEEL---ELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1101 ENIIKLRNRTDELERLIDSVEPKVIVKEVKKVEQDpELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKpkV 1180
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARLEERRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL--A 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1181 EIKEVVHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNvtftelnvvrsqkptveykedvqevvklekspEILREI 1260
Cdd:COG1196 362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE--------------------------------ELEEAE 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1261 DRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDv 1340
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE- 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1341 vydLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSNRRQLE-REVQQLRALVEDREKMLNFQEER 1419
Cdd:COG1196 489 ---AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEaALAAALQNIVVEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1420 DKKLAAEKELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDIL 1499
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1500 QREKFMEKTIYKEVIRVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKDKIERAENTKRtwSREESDLQRARNLAL 1579
Cdd:COG1196 646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE--LAEAEEERLEEELEE 723
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1717023833 1580 QEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEYDRqkrAQLGQELASLEGEI 1635
Cdd:COG1196 724 EALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL---EELERELERLEREI 776
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1195-1556 |
1.65e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.60 E-value: 1.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1195 ETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNvvrsqkptvEYKEDVQEVVKLEksPEILREIDRLKQQRNDIVTTS 1274
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELE---------ELEEELEQLRKEL--EELSRQISALRKDLARLEAEV 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1275 NRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYEndplLEKEAEHLRQEVRNESQRRrevedvvydLQNKYMLLErr 1354
Cdd:TIGR02168 743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE----AEAEIEELEAQIEQLKEEL---------KALREALDE-- 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1355 kpeekvvvqevvllqkdpkLREEHNRLQTSFDEETSNRRQLEREvqqlralVEDREKMLNFQEERDKKLAAEKElrQITL 1434
Cdd:TIGR02168 808 -------------------LRAELTLLNEEAANLRERLESLERR-------IAATERRLEDLEEQIEELSEDIE--SLAA 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1435 RIKEIEESPPAVQEKIvmeEVVKIEKDpVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDiLQREKFMEKTIYKEVI 1514
Cdd:TIGR02168 860 EIEELEELIEELESEL---EALLNERA-SLEEALALLRSELEELSEELRELESKRSELRRELE-ELREKLAQLELRLEGL 934
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1717023833 1515 RVEKDKILENERVRVR-------ELYNKERNSRQDAEEEIRRLKDKIER 1556
Cdd:TIGR02168 935 EVRIDNLQERLSEEYSltleeaeALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
213-388 |
2.28e-07 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 53.60 E-value: 2.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 213 LYNHLHGCTKELVYLNDQQSKILKQNWSDQMQDSTDVRRQYENFKtNDLLSQEEFVNNLQDDGVRMIELKHPAVESIQTH 292
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDYGDDLESVEALLKKHEALE-AELAAHEERVEALNELGEQLIEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 293 QDALKNEWQNFLNLCICQESHLKNVENYKKFQEDADAVSQTLKKVNSNLDTNYSKDATGATSDLLGLLEKDEKTLNQAEK 372
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELEEELEAHEP 160
|
170
....*....|....*.
gi 1717023833 373 DIESLKQRSLEIPPLN 388
Cdd:cd00176 161 RLKSLNELAEELLEEG 176
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
901-1441 |
3.11e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 3.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 901 TRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKRPIERLEEKEVVQYYRD-----PKLESSVSALKNQVENEYRQ 975
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEllaelARLEQDIARLEERRRELEER 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 976 REITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRDPELDNQASRLSHDIKLLREENSSLSTELERLKREVLILEQ 1055
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1056 KQPNIKEKVVVKEVVKLERDpEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERLIDSVEpkviVKEVKKVEQD 1135
Cdd:COG1196 398 LAAQLEELEEAEEALLERLE-RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL----ELLAELLEEA 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1136 PELLKECAKLRTLIDEERRKSSTLIRELTELQTKY-TVKEKQKPKV--EIKEVVHEIFQVDPETEKEIA--------RLK 1204
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLeGVKAALLLAGlrGLAGAVAVLIGVEAAYEAALEaalaaalqNIV 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1205 REIQNASSKRTNYEKEVN---VTFTELNVVRSQKPTVEYKEDVQEV-------VKLEKSPEILREIDRLKQQRNDIVTTS 1274
Cdd:COG1196 553 VEDDEVAAAAIEYLKAAKagrATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRTLVAARL 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1275 NRYQEQLTKLRVDRDEW---------------KRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVED 1339
Cdd:COG1196 633 EAALRRAVTLAGRLREVtlegeggsaggsltgGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1340 VVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEH--NRLQTSFDEETSNRR--QLEREVQQL-----RALVEDRE 1410
Cdd:COG1196 713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEalEELPEPPDLEELEREleRLEREIEALgpvnlLAIEEYEE 792
|
570 580 590
....*....|....*....|....*....|....*.
gi 1717023833 1411 kmlnfQEERDKKLAAEKE-----LRQITLRIKEIEE 1441
Cdd:COG1196 793 -----LEERYDFLSEQREdleeaRETLEEAIEEIDR 823
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1197-1669 |
3.30e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.69 E-value: 3.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1197 EKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKptveYKEDVQEVVKLEkspeilREIDRLKQQRNDIVTTSNR 1276
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEAQI----RGNGGDRLEQLE------REIERLERELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1277 YQEQLTKLRV----DRDEWKRERSKVetklvnkevvkyendpllekeaehlRQEVRNESQRRREVEDVVYDLQNKYMLLE 1352
Cdd:COG4913 364 LEALLAALGLplpaSAEEFAALRAEA-------------------------AALLEALEEELEALEEALAEAEAALRDLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1353 RRKPeekvvvqevvllqkdpKLREEHNRLQtsfdeetSNRRQLEREVQQLRALVED----REKMLNF--------QEERD 1420
Cdd:COG4913 419 RELR----------------ELEAEIASLE-------RRKSNIPARLLALRDALAEalglDEAELPFvgelievrPEEER 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1421 KKLAAEKELRQITLRIKEIEESPPAVQE---------KIVMEEVVKIEKDPVLEK-SANTL--RLD---------LDKER 1479
Cdd:COG4913 476 WRGAIERVLGGFALTLLVPPEHYAAALRwvnrlhlrgRLVYERVRTGLPDPERPRlDPDSLagKLDfkphpfrawLEAEL 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1480 SQFFNVQReCKNLQAkidiLQREKF---MEKTIYKEVIRVEKDKileneRVRVRELY-----NKERnsRQDAEEEIRRLK 1551
Cdd:COG4913 556 GRRFDYVC-VDSPEE----LRRHPRaitRAGQVKGNGTRHEKDD-----RRRIRSRYvlgfdNRAK--LAALEAELAELE 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1552 DKIERAENTKRTWSREESDLQRARNL--ALQEKSSLENDLRELGRQKQQNTVFL------SKESELLTQRTEYDRQKRAQ 1623
Cdd:COG4913 624 EELAEAEERLEALEAELDALQERREAlqRLAEYSWDEIDVASAEREIAELEAELerldasSDDLAALEEQLEELEAELEE 703
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1717023833 1624 LGQELASLEGEILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:COG4913 704 LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
907-1209 |
4.66e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 4.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 907 LQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKRPIERLEEKEVVQYYRDpkLESSVSALKNQVENEYRQREITQSEIEGV 986
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA--LRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 987 NKKIIQIDSQRKTIKPQLLTKEVTQIDRDPELDNQASRLshdiKLLREENSSLSTELERLKREVLILEQKQPNikekvvv 1066
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL----KALREALDELRAELTLLNEEAANLRERLES------- 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1067 kevvkLERDPEMV-KAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERLIDSVEpkviVKEVKKVEQDPELLKECAKL 1145
Cdd:TIGR02168 829 -----LERRIAATeRRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL----NERASLEEALALLRSELEEL 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1146 RTLIDEERRKSSTLIRELTELQTKYT--VKEKQKPKVEI---KEVVHEIFQVDPE---------------TEKEIARLKR 1205
Cdd:TIGR02168 900 SEELRELESKRSELRRELEELREKLAqlELRLEGLEVRIdnlQERLSEEYSLTLEeaealenkieddeeeARRRLKRLEN 979
|
....
gi 1717023833 1206 EIQN 1209
Cdd:TIGR02168 980 KIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
888-1497 |
5.81e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 5.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 888 TQQNLRSENALRSTrdteaLQSQLK--EEQDKVA----EVQRTLEEHRTQLLLLKtkrpIERLEEKEVvqyyrdpKLESS 961
Cdd:COG1196 184 TEENLERLEDILGE-----LERQLEplERQAEKAeryrELKEELKELEAELLLLK----LRELEAELE-------ELEAE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 962 VSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLtkevtqidrdpELDNQASRLSHDIKLLREENSSLST 1041
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-----------ELLAELARLEQDIARLEERRRELEE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1042 ELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERLIDSVE 1121
Cdd:COG1196 317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1122 PKVIVKEVKKVEQDpELLKECAKLRTLIDEERRKSSTLIRELTELQTKY-----TVKEKQKPKVEIKEVVHEIFQVDPET 1196
Cdd:COG1196 397 ELAAQLEELEEAEE-ALLERLERLEEELEELEEALAELEEEEEEEEEALeeaaeEEAELEEEEEALLELLAELLEEAALL 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1197 EKEIARLKREIQNASSKR-------TNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKLEKSPEIlREIDRLKQQRND 1269
Cdd:COG1196 476 EAALAELLEELAEAAARLlllleaeADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA-ALAAALQNIVVE 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1270 IVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYM 1349
Cdd:COG1196 555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1350 LLERRKPEEKVVVQEVV--LLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEK 1427
Cdd:COG1196 635 ALRRAVTLAGRLREVTLegEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1428 ELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKersqffnVQRECKNLQAKID 1497
Cdd:COG1196 715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE-------LERELERLEREIE 777
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1167-1460 |
1.08e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.97 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1167 QTKYTVKEKQKPKVEIKEVVHEIFQVDPETEKEIARlKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQE 1246
Cdd:pfam17380 290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKAR-QAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQE 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1247 VVKLEKSPeiLREIDRLKQQRNDivtTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQE 1326
Cdd:pfam17380 369 EIAMEISR--MRELERLQMERQQ---KNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEE 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1327 VRNESQRRREVEdvvYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRL---------QTSFDEETSNRRQLER 1397
Cdd:pfam17380 444 RAREMERVRLEE---QERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKilekeleerKQAMIEEERKRKLLEK 520
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1717023833 1398 EVQQLRALVEDREKMLNFQEERDKKLAAEkELRQITLRIKEIEESPPAVQ----EKIVMEEVVKIEK 1460
Cdd:pfam17380 521 EMEERQKAIYEEERRREAEEERRKQQEME-ERRRIQEQMRKATEERSRLEamerEREMMRQIVESEK 586
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
784-1095 |
1.84e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 1.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 784 VDEIQRKDPEKTSVVKLSQDIQSSLNDYEAEAERYRLTLDPSVSASAAKRQRIIPLQQNVEAQEKDLVKRYTEAAVENQQ 863
Cdd:TIGR02168 686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 864 HLNQLAFASkvLEKTEAVDGIPTVTQQNLRSENALRSTRDT-EALQSQLKEEQDKVAEVQRTLEEHRTQLLLlkTKRPIE 942
Cdd:TIGR02168 766 LEERLEEAE--EELAEAEAEIEELEAQIEQLKEELKALREAlDELRAELTLLNEEAANLRERLESLERRIAA--TERRLE 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 943 RLEEKEVvqyyrdpKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQidrdPELDNQA 1022
Cdd:TIGR02168 842 DLEEQIE-------ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL----RELESKR 910
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717023833 1023 SRLSHDIKLLREENSSLSTELERLKREVLileqkqpNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFK 1095
Cdd:TIGR02168 911 SELRRELEELREKLAQLELRLEGLEVRID-------NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
893-1573 |
2.52e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 2.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 893 RSENALRSTRDTEALQSQLKEEQDKVAEVQRTLEE-------------HRTQLLLLKTKRPIERL---EEKEVVQYYRDP 956
Cdd:PTZ00121 1219 KAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEirkfeearmahfaRRQAAIKAEEARKADELkkaEEKKKADEAKKA 1298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 957 KLESSVSALKNQVEnEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRDPELDNQASRLSHDiKLLREEN 1036
Cdd:PTZ00121 1299 EEKKKADEAKKKAE-EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA-EKKKEEA 1376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1037 SSLSTELERLKREVLILEQKQPniKEKVVVKEVVKLERDPEMVKAARTLQMQVDDeifKRKSVE-ENIIKLRNRTDELER 1115
Cdd:PTZ00121 1377 KKKADAAKKKAEEKKKADEAKK--KAEEDKKKADELKKAAAAKKKADEAKKKAEE---KKKADEaKKKAEEAKKADEAKK 1451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1116 LIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTkytvKEKQKPKVEIKEVVHEIFQVDPE 1195
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK----AAEAKKKADEAKKAEEAKKADEA 1527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1196 TEKEIARLKREIQNASSKRTNYEKEvnvTFTELNVVRSQKPTVEYKEDVQEVVKLEKSPEILREID--RLKQQRNDIVTT 1273
Cdd:PTZ00121 1528 KKAEEAKKADEAKKAEEKKKADELK---KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEeaRIEEVMKLYEEE 1604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1274 SNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLleKEAEHLRQE-----VRNESQRRREVEDvvydlqnKY 1348
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK--KKAEELKKAeeenkIKAAEEAKKAEED-------KK 1675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1349 MLLERRKPEEKVVVQEVVLLQKDPKLREEHnRLQTSFDEETSNRRQLEREVQQLRALVEDREKmlnfQEERDKKLAAE-- 1426
Cdd:PTZ00121 1676 KAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKK----EAEEDKKKAEEak 1750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1427 -KELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDilqREKFM 1505
Cdd:PTZ00121 1751 kDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVIN---DSKEM 1827
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1717023833 1506 EKTIYKEVI-----RVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKDKIERAENTKRTWSREESDLQR 1573
Cdd:PTZ00121 1828 EDSAIKEVAdsknmQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIER 1900
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
873-1441 |
2.66e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.76 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 873 KVLEKTEAVDGIptVTQQNLRSENALRSTRDTEALQSQLKEEQDKVAEVQRTLEEHRtqllllktkrpiERLEEKEVvqy 952
Cdd:PRK03918 183 KFIKRTENIEEL--IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK------------EEIEELEK--- 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 953 yRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKE--VTQIDRDPELDNQASRLSHDIK 1030
Cdd:PRK03918 246 -ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEfyEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1031 LLREENSslstELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRT 1110
Cdd:PRK03918 325 GIEERIK----ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1111 DELERLIDSVEPKVIvkevkkveqdpELLKECAKLRTLIDE---ERRKSSTLIRELTELQTKYTVKEKQKPKVEIKEVVH 1187
Cdd:PRK03918 401 EEIEEEISKITARIG-----------ELKKEIKELKKAIEElkkAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1188 EIFQVDPETEKEIARLKREIQNASSKRTNYE-----KEVNVTFTELNVVRSQKPTVEYKEDVQEVVKLEKspeilrEIDR 1262
Cdd:PRK03918 470 EIEEKERKLRKELRELEKVLKKESELIKLKElaeqlKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKG------EIKS 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1263 LKQQRNDIvttsNRYQEQLTKLRVDRDEWKRERSKVETKLVN-------------KEVVKYENDPLLEKEAEH-LRQEVR 1328
Cdd:PRK03918 544 LKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEElgfesveeleerlKELEPFYNEYLELKDAEKeLEREEK 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1329 NESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQE------VVLLQKDPKLREEHNRLQTSFDEETSNRRQLEREVQQL 1402
Cdd:PRK03918 620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKyseeeyEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
|
570 580 590
....*....|....*....|....*....|....*....
gi 1717023833 1403 RALVEDREKMLNFQEERDKKLAAEKELRQITLRIKEIEE 1441
Cdd:PRK03918 700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLK 738
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1394-1669 |
7.56e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 51.28 E-value: 7.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1394 QLEREVQQLRAlVEDREKMLNFQEERDKKLAAEKE--LRQITLRiKEIEESPPAVQEKIVMEEVVKIEKDpvleksantl 1471
Cdd:pfam17380 273 QLLHIVQHQKA-VSERQQQEKFEKMEQERLRQEKEekAREVERR-RKLEEAEKARQAEMDRQAAIYAEQE---------- 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1472 RLDLDKERsQFFNVQRECKNLQAKiDILQREKFMEKTIYKEVIRVEKDKILENERVRvRELynkERNSRQDAEEEIRRLK 1551
Cdd:pfam17380 341 RMAMERER-ELERIRQEERKRELE-RIRQEEIAMEISRMRELERLQMERQQKNERVR-QEL---EAARKVKILEEERQRK 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1552 DKIERAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEYDRQKR-AQLGQELAS 1630
Cdd:pfam17380 415 IQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRdRKRAEEQRR 494
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1717023833 1631 --LEGEILKEKDQIYEKE--RTIRELQSKANREEINQETQLRE 1669
Cdd:pfam17380 495 kiLEKELEERKQAMIEEErkRKLLEKEMEERQKAIYEEERRRE 537
|
|
| Plectin |
pfam00681 |
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous ... |
1678-1706 |
1.46e-05 |
|
Plectin repeat; This family includes repeats from plectin, desmoplakin, envoplakin and bullous pemphigoid antigen.
Pssm-ID: 459901 Cd Length: 39 Bit Score: 43.47 E-value: 1.46e-05
10 20
....*....|....*....|....*....
gi 1717023833 1678 ILDPDTGMDMSPYEAYRRGIIDRNQYIQL 1706
Cdd:pfam00681 11 IIDPVTGERLSVEEAVKRGLIDPETAQKL 39
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1848-1880 |
1.56e-05 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 43.62 E-value: 1.56e-05
10 20 30
....*....|....*....|....*....|...
gi 1717023833 1848 KLLEAQAATGGIIDIITKDRYSVHKAIDKGLID 1880
Cdd:smart00250 2 RLLEAQSAIGGIIDPETGQKLSVEEALRRGLID 34
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1030-1670 |
1.83e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.97 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1030 KLLREENSSLSTELERLKREVLILE----QKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFKRKSVEENIIK 1105
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEelklQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1106 LRNRTDELERLIDSVEPKVIVKEVKKVE---QDPELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEI 1182
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQVLKENKEeekEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1183 KEVVHEIFQVDPETEKEIARLKREIQN----ASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKLEKSPEILR 1258
Cdd:pfam02463 329 ELKKEKEEIEELEKELKELEIKREAEEeeeeELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1259 EIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVE 1338
Cdd:pfam02463 409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1339 DVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSF----DEETSNRRQLEREVQQLRALVEDREKMLN 1414
Cdd:pfam02463 489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGvaveNYKVAISTAVIVEVSATADEVEERQKLVR 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1415 FQEERDK---KLAAEKELRQITLRIKEIEESPPAVQE----KIVMEEVVKIEKDPVLEKSANTLRLDLDKER-----SQF 1482
Cdd:pfam02463 569 ALTELPLgarKLRLLIPKLKLPLKSIAVLEIDPILNLaqldKATLEADEDDKRAKVVEGILKDTELTKLKESakakeSGL 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1483 FNVQRECKNLQAKIDILQREKFMEKTIYKEVIRVEKDKILENERVRVRELYNKERNSrQDAEEEIRRLKDKIERAENTKR 1562
Cdd:pfam02463 649 RKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE-QREKEELKKLKLEAEELLADRV 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1563 TwsREESDLQRARNLALQEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEGEILKEKDQI 1642
Cdd:pfam02463 728 Q--EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRA 805
|
650 660
....*....|....*....|....*...
gi 1717023833 1643 YEKERTIRELQSKANREEINQETQLRET 1670
Cdd:pfam02463 806 LEEELKEEAELLEEEQLLIEQEEKIKEE 833
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
803-1351 |
2.86e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.27 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 803 DIQSSLNDYEAEAERYRLTLDPSVSASAAKRQRIIPLQQnVEAQEKDLVKRYTEAAVENQqhlnqlAFASKVLEKTEAVD 882
Cdd:PRK02224 217 ELDEEIERYEEQREQARETRDEADEVLEEHEERREELET-LEAEIEDLRETIAETERERE------ELAEEVRDLRERLE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 883 GIPTvTQQNLRSENALRSTrDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKrpIERLEEKEVVQYYRDPKLESSV 962
Cdd:PRK02224 290 ELEE-ERDDLLAEAGLDDA-DAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE--AESLREDADDLEERAEELREEA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 963 SALKNQVENEYRQREITQSEIEGVNKkiiQIDSQRKTIkpqlltkEVTQIDRDpELDNQASRLSHDIKLLREENSSLSTE 1042
Cdd:PRK02224 366 AELESELEEAREAVEDRREEIEELEE---EIEELRERF-------GDAPVDLG-NAEDFLEELREERDELREREAELEAT 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1043 LERL-----KREVLILEQKQPNIKEKVVvkevvklerDPEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRtdeLERLI 1117
Cdd:PRK02224 435 LRTArerveEAEALLEAGKCPECGQPVE---------GSPHVETIEEDRERVEELEAELEDLEEEVEEVEER---LERAE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1118 DSVEPKVIVKEVKKVEQDPELLKECAklRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEI-----KEVVHEIFQV 1192
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEELIAER--RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEeaeeaREEVAELNSK 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1193 DPETEKEIARLKReIQNASSKRTNYEKEVNvtftELNVVRSQKPTV--EYKEDVQEvvKLEKSPEILREID--RLKQQRN 1268
Cdd:PRK02224 581 LAELKERIESLER-IRTLLAAIADAEDEIE----RLREKREALAELndERRERLAE--KRERKRELEAEFDeaRIEEARE 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1269 DiVTTSNRYQEQ----LTKLRVDRDEWKRERSKVETKLvnkevvkyendplleKEAEHLRQEvRNESQRRREVEDVVYD- 1343
Cdd:PRK02224 654 D-KERAEEYLEQveekLDELREERDDLQAEIGAVENEL---------------EELEELRER-REALENRVEALEALYDe 716
|
570
....*....|.
gi 1717023833 1344 ---LQNKYMLL 1351
Cdd:PRK02224 717 aeeLESMYGDL 727
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1260-1666 |
3.05e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 3.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1260 IDRLKQQRNDIVTTSNR----YQEQLTKLRVDRDEWKRERSKVETKLVNKEvvkyendpLLEKEAEHLRQEVRNESQRRR 1335
Cdd:COG4717 48 LERLEKEADELFKPQGRkpelNLKELKELEEELKEAEEKEEEYAELQEELE--------ELEEELEELEAELEELREELE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1336 EVEDV--VYDLQNKYMLLERRKPEEKVVVQEVVLLQKDpkLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKML 1413
Cdd:COG4717 120 KLEKLlqLLPLYQELEALEAELAELPERLEELEERLEE--LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1414 --NFQEERDKKLAAEKELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQFFNVQRECKN 1491
Cdd:COG4717 198 aeELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1492 LQAKI--------DILQREKFMEKTIYKEVIRVEKDKILENERVR--VRELYNKERNSRQDAEE---EIRRLKDKIERAE 1558
Cdd:COG4717 278 VLFLVlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEelLAALGLPPDLSPEELLElldRIEELQELLREAE 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1559 NTKRTWSREESDLQRARNLALQEKSSLEnDLRELGRQKQQNTVFLSKESELLTQRTEYD---------------RQKRAQ 1623
Cdd:COG4717 358 ELEEELQLEELEQEIAALLAEAGVEDEE-ELRAALEQAEEYQELKEELEELEEQLEELLgeleellealdeeelEEELEE 436
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1717023833 1624 LGQELASLEGEILKEKDQIYEKERTIRELQSKANREEINQETQ 1666
Cdd:COG4717 437 LEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELE 479
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
826-1520 |
5.50e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.18 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 826 VSASAAKRQRIIPLQQN---VEAQEKDLvkryTEAAVENQQhlNQLAFASKVLEKTEAV-DGIPTVTQQNLRSENALRST 901
Cdd:pfam05483 95 VSIEAELKQKENKLQENrkiIEAQRKAI----QELQFENEK--VSLKLEEEIQENKDLIkENNATRHLCNLLKETCARSA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 902 RDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKRPIERLEEKEvvqyyrdpKLESSVSALKNqVENEYrQREITQS 981
Cdd:pfam05483 169 EKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHF--------KLKEDHEKIQH-LEEEY-KKEINDK 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 982 EIEgVNKKIIQIDSQRKTIKPQLLTKEVTQiDRDPELDNQASRLSHDIKLLREENSSLSTELERLK----REVLILEQKQ 1057
Cdd:pfam05483 239 EKQ-VSLLLIQITEKENKMKDLTFLLEESR-DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKmslqRSMSTQKALE 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1058 PNIKEKVVVKEVVKLERDPEMvkaartlqmqvdDEIFKRKSVEENII-KLRNRTDELERLIDSVEPKVIVKEVKKVEQDP 1136
Cdd:pfam05483 317 EDLQIATKTICQLTEEKEAQM------------EELNKAKAAHSFVVtEFEATTCSLEELLRTEQQRLEKNEDQLKIITM 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1137 ELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTV----KEKQKPKVEIKEVVHEIFQVDPETEKEIARLKREIQNASS 1212
Cdd:pfam05483 385 ELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLldekKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKT 464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1213 KRTNYEKEVNVTFTELN---------VVRSQKPTVEYKEDVQE----VVKLEKSPEilrEIDRLKQQRNDIVTTSNRYQE 1279
Cdd:pfam05483 465 SEEHYLKEVEDLKTELEkeklknielTAHCDKLLLENKELTQEasdmTLELKKHQE---DIINCKKQEERMLKQIENLEE 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1280 QLTKLRVD----RDEWKRERSKVETKLVNKE----------VVKYENDPLLEKEAEHLRQEVRNESQRRREVEDvvydlQ 1345
Cdd:pfam05483 542 KEMNLRDElesvREEFIQKGDEVKCKLDKSEenarsieyevLKKEKQMKILENKCNNLKKQIENKNKNIEELHQ-----E 616
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1346 NKYMllerRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEETSN-RRQLEREVQQLRALVEDREKMLNFQEErdkkla 1424
Cdd:pfam05483 617 NKAL----KKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNyQKEIEDKKISEEKLLEEVEKAKAIADE------ 686
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1425 AEKELRQITLRIKEieesppAVQEKIVMEEVVKIEKDPVLEKSANTLRLDLDKERSQ----------FFNVQRECKNLQA 1494
Cdd:pfam05483 687 AVKLQKEIDKRCQH------KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQssakaaleieLSNIKAELLSLKK 760
|
730 740
....*....|....*....|....*.
gi 1717023833 1495 KIDILQREKFMEKTIYKEVIRVEKDK 1520
Cdd:pfam05483 761 QLEIEKEEKEKLKMEAKENTAILKDK 786
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
893-1663 |
6.90e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.12 E-value: 6.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 893 RSENALRSTRDTEALQSQLKEEQDKVAEVQrtleEHRTQLLLLKTKRPIERLEEKEVVQyyRDPKLESSVSALKNQvENE 972
Cdd:TIGR00606 174 KFDEIFSATRYIKALETLRQVRQTQGQKVQ----EHQMELKYLKQYKEKACEIRDQITS--KEAQLESSREIVKSY-ENE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 973 YRQREITQSEIEGVNKKIIQIDSQRKTIKP-----QLLTKEVTQIDRDPEL--DNQASRLSH----DIKLLREENSSLST 1041
Cdd:TIGR00606 247 LDPLKNRLKEIEHNLSKIMKLDNEIKALKSrkkqmEKDNSELELKMEKVFQgtDEQLNDLYHnhqrTVREKERELVDCQR 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1042 ELERLKREVLILEQKQPNIkekvvvkevvklerdpEMVKAARTLQMQVDDEIFKRKSVEENIIKLRNRTDELERlidsve 1121
Cdd:TIGR00606 327 ELEKLNKERRLLNQEKTEL----------------LVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFER------ 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1122 pkvivkevkkveqDPELLKECAKLRTLIDE-ERRKSSTLIRELTELQTKYTVKEKQKPKVEI-KEVVHEIFQVDPET-EK 1198
Cdd:TIGR00606 385 -------------GPFSERQIKNFHTLVIErQEDEAKTAAQLCADLQSKERLKQEQADEIRDeKKGLGRTIELKKEIlEK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1199 EIARLK---REIQN--ASSKRTnYEKEVNVTFTELNVVRSQKPTVEYKEDVQEVVKLEKSPEILREIDRLKQQ--RNDIV 1271
Cdd:TIGR00606 452 KQEELKfviKELQQleGSSDRI-LELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEmeQLNHH 530
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1272 TTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVRNESQRRREVEDVVYDL---QNKY 1348
Cdd:TIGR00606 531 TTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLeqnKNHI 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1349 MLLERRKPEEKVVVQE--------VVLLQKDPKLREEHNR-------------LQTSFDEETSNRRQ-----LEREVQ-- 1400
Cdd:TIGR00606 611 NNELESKEEQLSSYEDklfdvcgsQDEESDLERLKEEIEKsskqramlagataVYSQFITQLTDENQsccpvCQRVFQte 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1401 -QLRALVEDREKMLNF----QEERDKKLAAEKELRQITLRIKEIEESPPAVQEKIVMEEVVKIEKdpvLEKSANTLRLDL 1475
Cdd:TIGR00606 691 aELQEFISDLQSKLRLapdkLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQK---VNRDIQRLKNDI 767
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1476 DKERSQFFNVQRE---CKNLQAKIDILQRekFMEKTiyKEVIRVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKD 1552
Cdd:TIGR00606 768 EEQETLLGTIMPEeesAKVCLTDVTIMER--FQMEL--KDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVS 843
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1553 KIERAENTKRTWSREESDLQRARNLALQEKSSLENDLRELGRQKQQnTVFLSKESELLTQRTeydRQKRAQLGQELASLE 1632
Cdd:TIGR00606 844 KIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQ-LVELSTEVQSLIREI---KDAKEQDSPLETFLE 919
|
810 820 830
....*....|....*....|....*....|...
gi 1717023833 1633 GEILKEKDQIYEKERTIRELQSKAN--REEINQ 1663
Cdd:TIGR00606 920 KDQQEKEELISSKETSNKKAQDKVNdiKEKVKN 952
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
709-1270 |
1.08e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.62 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 709 RQKAAVQRLNERYHAVADQLDQREKMLRDTNLTYQQFRSASDNMSSWLNNIpKNQVKSTDGpsQVNYKLQSQKRLVDEIQ 788
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL-LAELARLEQ--DIARLEERRRELEERLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 789 RKDPEKTSVVKLSQDIQSSLNDYEAEAERyrltLDPSVSASAAKRQRIIPLQQNVEAQEKDLVKRYTEAAVENQQHLNQL 868
Cdd:COG1196 320 ELEEELAELEEELEELEEELEELEEELEE----AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 869 AFASKVLEKTEAvdgiptvtQQNLRSENALRSTRDTEALQSQLKEEQDKVAEVQRTLEEHRTQLLLLKTKrpIERLEEKE 948
Cdd:COG1196 396 AELAAQLEELEE--------AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE--EEALLELL 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 949 VVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRDPE-----LDNQAS 1023
Cdd:COG1196 466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAayeaaLEAALA 545
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1024 RLSHDIklLREENSSLSTELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFKRKSVEENI 1103
Cdd:COG1196 546 AALQNI--VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1104 IKLRNRTDELERLIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEIK 1183
Cdd:COG1196 624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1184 EVVHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDVQEvvklekspeilREIDRL 1263
Cdd:COG1196 704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE-----------RELERL 772
|
....*..
gi 1717023833 1264 KQQRNDI 1270
Cdd:COG1196 773 EREIEAL 779
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1512-1658 |
1.21e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.16 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1512 EVIRVEKDKILENERVRVRELYNKERNSRQDAEEEIRRLKDKIERAENtkrtwsreesdlqrarnlalqEKSSLENDLRE 1591
Cdd:COG2433 380 EALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEA---------------------EVEELEAELEE 438
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1717023833 1592 LGRQKQQntvflsKESELLTQRTEYDRQKRAQlgQELASLEGEILKEKDQIYEKERTIRELQSKANR 1658
Cdd:COG2433 439 KDERIER------LERELSEARSEERREIRKD--REISRLDREIERLERELEEERERIEELKRKLER 497
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1420-1635 |
1.30e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1420 DKKLAAEKELRQITLRIKEIEESPPAVQEKIvmEEVVKIEKDpvLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDIL 1499
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEE--KALLKQLAA--LERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1500 QREKFMEKTIYKEVIRV-------EKDKILEN-----ERVRVRELYNKERNSRQDAEEEIRRLKDKIERaenTKRTWSRE 1567
Cdd:COG4942 96 RAELEAQKEELAELLRAlyrlgrqPPLALLLSpedflDAVRRLQYLKYLAPARREQAEELRADLAELAA---LRAELEAE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1717023833 1568 ESDLQRARNLALQEKSSLENDLRElgrqKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEGEI 1635
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1146-1653 |
2.31e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.50 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1146 RTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEIKEVVHEIFQVDPETEKEIARLKR----EIQNASSKRtnyEKEV 1221
Cdd:TIGR00618 92 RTLRCTRSHRKTEQPEQLYLEQKKGRGRILAAKKSETEEVIHDLLKLDYKTFTRVVLLPQgefaQFLKAKSKE---KKEL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1222 NVTFTELNVVRsQKPTVEYKEDVQEVVKLEKSPEILREIDRLKQQRNDIVTTSnryQEQLTKLRVDRDEWKRERSKVETK 1301
Cdd:TIGR00618 169 LMNLFPLDQYT-QLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER---KQVLEKELKHLREALQQTQQSHAY 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1302 LVNKEVVKYENDPLlekeaEHLRQEVRNESQRRREVEDVVYDLQNKymlLERRKPEEKVVVQEVVLLQKDPKLREEHNRL 1381
Cdd:TIGR00618 245 LTQKREAQEEQLKK-----QQLLKQLRARIEELRAQEAVLEETQER---INRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1382 QtsfdeetSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEKELRQIT---LRIKEIEESPPAVQEKIVMEEVVKi 1458
Cdd:TIGR00618 317 Q-------SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHevaTSIREISCQQHTLTQHIHTLQQQK- 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1459 EKDPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFMEKTiYKEVIRVEKDKILENERVRVRELynkeRN 1538
Cdd:TIGR00618 389 TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQR-YAELCAAAITCTAQCEKLEKIHL----QE 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1539 SRQDAEEEIRRLKDKIERAENTKRTWSREESDLQRARnlalQEKSSLENDLRELGRQKQQntvflSKESELLTQRTEYDR 1618
Cdd:TIGR00618 464 SAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQ----EEPCPLCGSCIHPNPARQD-----IDNPGPLTRRMQRGE 534
|
490 500 510
....*....|....*....|....*....|....*
gi 1717023833 1619 QKRAQLGQELASLEGEILKEKDQIYEKERTIRELQ 1653
Cdd:TIGR00618 535 QTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ 569
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
214-315 |
2.34e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 42.32 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 214 YNHLHGCTKELVYLNDQQSKILKQNWSDqmqDSTDVRRQYENFKT--NDLLSQEEFVNNLQDDGVRMIELKHPAVESIQT 291
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGK---DLESVEALLKKHEAfeAELEAHEERVEALNELGEQLIEEGHPDAEEIEE 77
|
90 100
....*....|....*....|....
gi 1717023833 292 HQDALKNEWQNFLNLCICQESHLK 315
Cdd:smart00150 78 RLEELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
141-314 |
2.60e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 44.36 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 141 LKQKQAEIEGGQYGPGLPDVEKQVAEHNILQQEIEEYGPQIQNL----------------YIPET-AAVKSQYRDLLEAS 203
Cdd:cd00176 16 LSEKEELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALnelgeqlieeghpdaeEIQERlEELNQRWEELRELA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 204 DWRSRNLG---SLYNHLHGCTKELVYLNDQQSKILKQNWSDQMQDSTDVRRQYENFKtNDLLSQEEFVNNLQDDGVRMIE 280
Cdd:cd00176 96 EERRQRLEealDLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLKKHKELE-EELEAHEPRLKSLNELAEELLE 174
|
170 180 190
....*....|....*....|....*....|....*
gi 1717023833 281 LKHPAV-ESIQTHQDALKNEWQNFLNLCICQESHL 314
Cdd:cd00176 175 EGHPDAdEEIEEKLEELNERWEELLELAEERQKKL 209
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1376-1708 |
3.69e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1376 EEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEKELRQITLRIKEIEESPPAVQEkivmeev 1455
Cdd:COG4717 88 EEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRE------- 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1456 vkiekdpvleksantLRLDLDKERSQFFNVQRECKNLQAKIDILQREKFmeKTIYKEVIRvekdkiLENERVRVRELYNK 1535
Cdd:COG4717 161 ---------------LEEELEELEAELAELQEELEELLEQLSLATEEEL--QDLAEELEE------LQQRLAELEEELEE 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1536 ERNSRQDAEEEIRRLKDKIERAENTKRTWSREESDLQRARNLALQEKSSLENDLRE---------------LGRQKQQNT 1600
Cdd:COG4717 218 AQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILtiagvlflvlgllalLFLLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1601 VFLSKESELLTQRTEYDRQKRAQLGQELASLEGEILKEKDQIYEKERTIRELQsKANREEINQETQLRETNVSTKISILD 1680
Cdd:COG4717 298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-ELLREAEELEEELQLEELEQEIAALL 376
|
330 340
....*....|....*....|....*...
gi 1717023833 1681 PDTGMDMSpyEAYRRGIIDRNQYIQLQE 1708
Cdd:COG4717 377 AEAGVEDE--EELRAALEQAEEYQELKE 402
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1305-1708 |
3.98e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1305 KEVVKYENDPLLEKEAEHLRQEVRnESQRRREVEDVVYDLQNKYMlleRRKPEEKVVVQEVVLLQKDP--KLREEHNRLQ 1382
Cdd:pfam15921 65 RKIIAYPGKEHIERVLEEYSHQVK-DLQRRLNESNELHEKQKFYL---RQSVIDLQTKLQEMQMERDAmaDIRRRESQSQ 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1383 TSFdeetsnRRQLEREVQQLRALVEDREKMLN-----FQEERDKKLAAEKELRQITLRIKEIEE-SPPAVQEKIVMEEVV 1456
Cdd:pfam15921 141 EDL------RNQLQNTVHELEAAKCLKEDMLEdsntqIEQLRKMMLSHEGVLQEIRSILVDFEEaSGKKIYEHDSMSTMH 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1457 KIEKDPVLEKSANTLRLDLDKERSQFFNVQRECKNLQAkidilQREKFMEKTIYKEVIRVEKdkILENERVRVRELYNKE 1536
Cdd:pfam15921 215 FRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKS-----ESQNKIELLLQQHQDRIEQ--LISEHEVEITGLTEKA 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1537 RNSRQDAEEEIRRLKDKIERAENTKRTWSREESDLQRArnlalqeKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEY 1616
Cdd:pfam15921 288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLEST-------VSQLRSELREAKRMYEDKIEELEKQLVLANSELTE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1617 DRQKRAQLGQELASLEGEILKEKDQIYEKERTIrELQSKANREeinqetqlretnvstkisILDPDTGMDMSpYEAYRRG 1696
Cdd:pfam15921 361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL-SLEKEQNKR------------------LWDRDTGNSIT-IDHLRRE 420
|
410
....*....|..
gi 1717023833 1697 IIDRNQYIQLQE 1708
Cdd:pfam15921 421 LDDRNMEVQRLE 432
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1154-1628 |
6.63e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 6.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1154 RKSSTLIRELTELQTKytVKEKQKPKVEIKEVVHEIFqvdpETEKEIARLKREIQNASSKRTNYEKEVnvtftelnvvrs 1233
Cdd:COG4717 64 RKPELNLKELKELEEE--LKEAEEKEEEYAELQEELE----ELEEELEELEAELEELREELEKLEKLL------------ 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1234 qkptvEYKEDVQEVVKLEKspEILREIDRLKQQRNDIvttsNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYEND 1313
Cdd:COG4717 126 -----QLLPLYQELEALEA--ELAELPERLEELEERL----EELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1314 PLLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVqevvllqkdpKLREEHNRL------------ 1381
Cdd:COG4717 195 QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE----------RLKEARLLLliaaallallgl 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1382 ---QTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQE-ERDKKLAAEKELRQITL-RIKEIEESPPAVQEKIVMEEVV 1456
Cdd:COG4717 265 ggsLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEaEELQALPALEELEEEELeELLAALGLPPDLSPEELLELLD 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1457 KIEKDPVLEKSANTLRLDLDKERsqffnVQRECKNLQAKIDILQREKFmektiYKEVIRVEKDKILENERVRVRELYNKE 1536
Cdd:COG4717 345 RIEELQELLREAEELEEELQLEE-----LEQEIAALLAEAGVEDEEEL-----RAALEQAEEYQELKEELEELEEQLEEL 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1537 RNSRQDAEEEI--RRLKDKIERAENTKRTWSREESDLQRARNLALQEKSSLENDlRELGRQKQQntvflskESELLTQRT 1614
Cdd:COG4717 415 LGELEELLEALdeEELEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQE-------LEELKAELR 486
|
490
....*....|....*
gi 1717023833 1615 EYDRQ-KRAQLGQEL 1628
Cdd:COG4717 487 ELAEEwAALKLALEL 501
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
875-1455 |
6.81e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.96 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 875 LEKTEAVDGIPTVTQQNLRSenaLRSTRDTEALQSQLkEEQDKVAEVQRTLEEHRTQLLLLKTKRPIERLEEKEVVQYYR 954
Cdd:TIGR00618 172 LFPLDQYTQLALMEFAKKKS---LHGKAELLTLRSQL-LTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQ 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 955 DPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQLLTKEVTQIDRDPELDNQ------ASRLSHD 1028
Cdd:TIGR00618 248 KREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTelqskmRSRAKLL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1029 IKLLREENSSLSTELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQVDDEIFKRKSVEENIIKLRN 1108
Cdd:TIGR00618 328 MKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQR 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1109 RTDELERLIDSVEPKVIVKEVKKVEQDPElLKECAKLRTLIDEERRKSSTLIRELTELQTKYTVKEKQKPKVEikevvhE 1188
Cdd:TIGR00618 408 EQATIDTRTSAFRDLQGQLAHAKKQQELQ-QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE------Q 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1189 IFQVDPETEKEIARLKREIQNASSKRTNYEKEVNVTFTELNVVRSQKPTVEYKEDvqEVVKLEKSPEILR-EIDRLKQQR 1267
Cdd:TIGR00618 481 IHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQ--TYAQLETSEEDVYhQLTSERKQR 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1268 ndivttsNRYQEQLTKLRVDRDEW--KRERSKVETKLVNKEVVKYEndPLLEKEAEHLRQEVRNESQRRREVEDVVYDLQ 1345
Cdd:TIGR00618 559 -------ASLKEQMQEIQQSFSILtqCDNRSKEDIPNLQNITVRLQ--DLTEKLSEAEDMLACEQHALLRKLQPEQDLQD 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1346 NKYMLLERRKPEEKVVVQEVVLLQKDPKLREEHNRLQTSFDEE---TSNRRQLEREVQQLRALVEDREKMLNFQEERDKK 1422
Cdd:TIGR00618 630 VRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKellASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREL 709
|
570 580 590
....*....|....*....|....*....|...
gi 1717023833 1423 LAAEKELRQitlRIKEIEESPPAVQEKIVMEEV 1455
Cdd:TIGR00618 710 ETHIEEYDR---EFNEIENASSSLGSDLAARED 739
|
|
| SH3_Tec_like |
cd11768 |
Src Homology 3 domain of Tec-like Protein Tyrosine Kinases; The Tec (Tyrosine kinase expressed ... |
407-444 |
9.97e-04 |
|
Src Homology 3 domain of Tec-like Protein Tyrosine Kinases; The Tec (Tyrosine kinase expressed in hepatocellular carcinoma) subfamily is composed of Tec, Btk, Bmx (Etk), Itk (Tsk, Emt), Rlk (Txk), and similar proteins. They are cytoplasmic (or nonreceptor) tyr kinases containing Src homology protein interaction domains (SH3, SH2) N-terminal to the catalytic tyr kinase domain. Most Tec subfamily members (except Rlk) also contain an N-terminal pleckstrin homology (PH) domain, which binds the products of PI3K and allows membrane recruitment and activation. In addition, some members contain the Tec homology (TH) domain, which contains proline-rich and zinc-binding regions. Tec kinases are expressed mainly by haematopoietic cells, although Tec and Bmx are also found in endothelial cells. B-cells express Btk and Tec, while T-cells express Itk, Txk, and Tec. Collectively, Tec kinases are expressed in a variety of myeloid cells such as mast cells, platelets, macrophages, and dendritic cells. Each Tec kinase shows a distinct cell-type pattern of expression. The function of Tec kinases in lymphoid cells have been studied extensively. They play important roles in the development, differentiation, maturation, regulation, survival, and function of B-cells and T-cells. SH3 domains are protein interaction domains that bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs. They play versatile and diverse roles in the cell including the regulation of enzymes, changing the subcellular localization of signaling pathway components, and mediating the formation of multiprotein complex assemblies.
Pssm-ID: 212702 [Multi-domain] Cd Length: 54 Bit Score: 38.79 E-value: 9.97e-04
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 407 DSGDVQLSRGEKYTLKDNSNPENWVVQSKQGETKTVPA 444
Cdd:cd11768 12 EPGDLPLEKGEEYVVLDDSNEHWWRARDKNGNEGYIPS 49
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1217-1670 |
1.79e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 43.49 E-value: 1.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1217 YEKEVNVTFTELNVVRSQKPT-VEYKEDVQEVvkLEKSPEILREIDRLKQQRNDIvttsnryQEQLTKLRVDRDEWKRE- 1294
Cdd:PRK02224 211 LESELAELDEEIERYEEQREQaRETRDEADEV--LEEHEERREELETLEAEIEDL-------RETIAETEREREELAEEv 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1295 ---RSKVETklvnkevvkyendplLEKEAEHLRQEVRNESQRRREVEDVVYDLQNKYMLLERRKPEEKVVVQEVVLLQKd 1371
Cdd:PRK02224 282 rdlRERLEE---------------LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE- 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1372 pKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNfqeerdkklAAEKELRQITLRIKEIEESPPAVQEKIv 1451
Cdd:PRK02224 346 -SLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIE---------ELEEEIEELRERFGDAPVDLGNAEDFL- 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1452 meEVVKIEKDPVLEKSAnTLRLDLDKERsqffNVQRECKNLQAKIDILQREKFMEKTIYKEVIrvekdkilENERVRVRE 1531
Cdd:PRK02224 415 --EELREERDELREREA-ELEATLRTAR----ERVEEAEALLEAGKCPECGQPVEGSPHVETI--------EEDRERVEE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1532 LynkeRNSRQDAEEEIRRLKDKIERAENTKRTWSREESDLQRARNL----------------ALQEKSSLENDLRELGRQ 1595
Cdd:PRK02224 480 L----EAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLeeliaerretieekreRAEELRERAAELEAEAEE 555
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1717023833 1596 KQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASLEgEILKEKDQIYEKERTIRELQSKanREEIN-QETQLRET 1670
Cdd:PRK02224 556 KREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREK--REALAeLNDERRER 628
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1371-1633 |
2.11e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1371 DPKLREEHNRLQTSFDEETSNRRQLEREVQQLRALVEDREKMLNFQEERDKKLAAEKELRQITLRIKEieesppavqeki 1450
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQ------------ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1451 vmeevvkiekdpvleksantLRLDLDKERSQffNVQRECKNLQAKIDILQREkfmektiykevirvekdkiLENERVRVR 1530
Cdd:COG4913 288 --------------------RRLELLEAELE--ELRAELARLEAELERLEAR-------------------LDALREELD 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1531 ELYNKERNSRQDAEEEIRRlkdKIERAENTKRTWSREESDLQR-ARNLALQEKSSLEnDLRELGRQKQQNTVFLSKESEL 1609
Cdd:COG4913 327 ELEAQIRGNGGDRLEQLER---EIERLERELEERERRRARLEAlLAALGLPLPASAE-EFAALRAEAAALLEALEEELEA 402
|
250 260 270
....*....|....*....|....*....|.
gi 1717023833 1610 LTQ------RTEYD-RQKRAQLGQELASLEG 1633
Cdd:COG4913 403 LEEalaeaeAALRDlRRELRELEAEIASLER 433
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1678-1703 |
2.41e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 37.46 E-value: 2.41e-03
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1541-1664 |
2.95e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1541 QDAEEEIRR-LKDKIERAENTKR---TWSREEsdLQRARNLALQEKSSLENDLRELGRQKQQNTVFLSKESELLTQRTEY 1616
Cdd:PRK12704 34 KEAEEEAKRiLEEAKKEAEAIKKealLEAKEE--IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEE 111
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1717023833 1617 DRQKRAQLGQELASLEgEILKEKDQIYEKERTIRELQSKANREEINQE 1664
Cdd:PRK12704 112 LEKKEKELEQKQQELE-KKEEELEELIEEQLQELERISGLTAEEAKEI 158
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1467-1658 |
4.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 4.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1467 SANTLRLDLDKERSQFFNVQRE-CKNLQAKIDIlQREKFME---KTI-YKEVIRVE---KDKILENERV-----RVRELY 1533
Cdd:COG4913 156 DIRALKARLKKQGVEFFDSFSAyLARLRRRLGI-GSEKALRllhKTQsFKPIGDLDdfvREYMLEEPDTfeaadALVEHF 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1534 NKERNSRQDAE---------EEIRRLKDKIERAENTKRTWSREESDL-----QRARNLALQEKSSLENDLRELGRQKQQN 1599
Cdd:COG4913 235 DDLERAHEALEdareqiellEPIRELAERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERL 314
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1717023833 1600 TvflSKESELLTQRTEYDRQKRAQLGQELASLEGEILKEKDQIYEKERTIRELQSKANR 1658
Cdd:COG4913 315 E---ARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAA 370
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1923-1960 |
6.15e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 36.31 E-value: 6.15e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1923 LPYLEVQHLTGGLIDPKKTGRIPVSDAVVTHMLDDSTA 1960
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| PLEC |
smart00250 |
Plectin repeat; |
1809-1846 |
8.77e-03 |
|
Plectin repeat;
Pssm-ID: 197605 Cd Length: 38 Bit Score: 35.92 E-value: 8.77e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1717023833 1809 KNFYDDSFPIAGIYDDTTGIKCTIRNAVAKNMVDPITA 1846
Cdd:smart00250 1 QRLLEAQSAIGGIIDPETGQKLSVEEALRRGLIDPETG 38
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1486-1669 |
9.67e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 9.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1486 QRECKNLQAKIDILQREKFMEKTIYKEVIRVEKDkiLENERVRVRELYNKERNSRQDAEEEIRRLKDKIERAENTKRTWS 1565
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAA--LERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1566 REESDLQRAR---------NLALQEKSSLEND-----LRELGRQKQQNTVFLSKESELLTQRTEYDRQKRAQLGQELASL 1631
Cdd:COG4942 104 EELAELLRALyrlgrqpplALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
|
170 180 190
....*....|....*....|....*....|....*...
gi 1717023833 1632 EGEILKEKDQIYEKERTIRELQSKANREEINQETQLRE 1669
Cdd:COG4942 184 EEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
778-1329 |
9.90e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.08 E-value: 9.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 778 QSQKRLVDEIQRKDPEKTSVVKLSQDIQSSLNDYEAEAERYRLTLDPSVSASAAKRQRIIPLQQNVEAQEKDLvKRYTEA 857
Cdd:COG1196 239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR-RELEER 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 858 AVENQQHLNQLAFASKVLEKTEAvdgipTVTQQNLRSENALRSTRDTEA-LQSQLKEEQDKVAEVQRTLEEHRTQLL--- 933
Cdd:COG1196 318 LEELEEELAELEEELEELEEELE-----ELEEELEEAEEELEEAEAELAeAEEALLEAEAELAEAEEELEELAEELLeal 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 934 --LLKTKRPIERLEEKEVVQYYRDPKLESSVSALKNQVENEYRQREITQSEIEGVNKKIIQIDSQRKTIKPQL---LTKE 1008
Cdd:COG1196 393 raAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLaelLEEA 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1009 VTQIDRDPELDNQASRLSHDIKLLREENSSLSTELERLKREVLILEQKQPNIKEKVVVKEVVKLERDPEMVKAARTLQMQ 1088
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1089 VDDEIFKRKSVEENIIKLRNRTDELERLIDSVEPKVIVKEVKKVEQDPELLKECAKLRTLIDEERRKSSTLIRELTELQT 1168
Cdd:COG1196 553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1169 KYTVKEKQKPKVEIKEVVHEIFQVDPETEKEIARLKREIQNASSKRTNYEKEVNvtftelnvvrsqkptVEYKEDVQEVV 1248
Cdd:COG1196 633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE---------------RLAEEELELEE 697
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717023833 1249 KLEKSPEILREIDRLKQQRNDIVTTSNRYQEQLTKLRVDRDEWKRERSKVETKLVNKEVVKYENDPLLEKEAEHLRQEVR 1328
Cdd:COG1196 698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
.
gi 1717023833 1329 N 1329
Cdd:COG1196 778 A 778
|
|
| |
