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Conserved domains on  [gi|1707074376|ref|WP_143004385|]
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dockerin type I domain-containing protein [Thermus arciformis]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF2135 super family cl46768
Uncharacterized protein conserved in bacteria (DUF2135); This domain, found in various ...
507-599 2.09e-14

Uncharacterized protein conserved in bacteria (DUF2135); This domain, found in various hypothetical prokaryotic proteins, has no known function.


The actual alignment was detected with superfamily member COG4676:

Pssm-ID: 481108  Cd Length: 125  Bit Score: 70.01  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 507 RVVLSW-TSGADLDLHLFYPDtpaAHHVYWQNPgvCPPAGEAcLEGDTLQGPGQEALRFTS-TGGSYRVYVHwYFGGGSW 584
Cdd:COG4676     9 RVVLTWdTDPADLDLHVVEPD---GEHVYYGNK--LTPNGGR-LDVDDTDGYGPEEFTIRKaPPGTYLVNVN-YYGNGGQ 81
                          90
                  ....*....|....*.
gi 1707074376 585 ATAGAQVQVF-NAGYP 599
Cdd:COG4676    82 APTTAKVTVYtNYGTP 97
COG1470 COG1470
Uncharacterized membrane protein [Function unknown];
210-647 1.68e-06

Uncharacterized membrane protein [Function unknown];


:

Pssm-ID: 441079 [Multi-domain]  Cd Length: 475  Bit Score: 51.01  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 210 VNPSLGAGLEVAPLRLALNPGESAYVLVGNSGNEPLPPLVLEAAPGLSVAEETPSGYAGRVYRVAASQSVSQGALLFRAG 289
Cdd:COG1470     3 AAGLVASSTVAAGALAALLDLTTPLVGSTVALTSTASALSGERTTLAALAATGGLVTATPVSPTSATLTLSVEVPSNATV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 290 NQARAVAVNGTAPDFLLGL-SGTPTGPVGGTAQATLTLTPLNGFTGTVSLSLVDPPAGVSLSPAG---LIVSGPDPVDLP 365
Cdd:COG1470    83 GTYLPITVTVAPYGLTLSVeSPSLEVAPGETVTYTVTLTNTGDEPDTVSLSAEGLPEGWTVTFTPdtsVSLAPGESKTVT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 366 LTLTLDPGLAPQDYPLTLRASGGSRTREVQFTLKAT-----DFALAGSPA-LTLPWGGMGSLGVAVLPQNGFATPLNLAL 439
Cdd:COG1470   163 LEVTPPANAEPGTYPVTVTATSGEDSSSASLTLTLTvtgsyELELSSTPTgRTVTPGESATFTVTVTNTGNGADLTNVTL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 440 KrqdgTPLPPGLALT-----TPTLPPSG-GPVGLQVQNP---PPGDYPLRLEATpqgGGATRSLDFTLTVTYSPEWRVV- 509
Cdd:COG1470   243 S----ASAPSGWTVSfepetIPSLAPGEsATVTLTVTVPadaTAGDYTVTVTAT---SDETASATLRLTVETSSLWGWIg 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 510 --------LSWTSGADLDLHLFYPDTPAAHHVYWQNPGVCPPAGEACLEGDTLQGPGQEALRFTSTGGSYRVYVHWYFGG 581
Cdd:COG1470   316 ylirkyggLGATGSLLVASVSLVVGAVVGTLTTPLLLTGFAGNGLLSAATAPLLLLLGLTLSLLSDVLVFTVGSAGVSAA 395
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1707074376 582 GSWATAGAQVQVFNAGYP---VGSFPAPGDPGGYGTWWHVLTVGPGGLEAGSGVAGIAPQGGLTPLGLP 647
Cdd:COG1470   396 AATAETSALTALGVGATGavgSGSASASVKVTGGAAVATGLTDATTLPGAGSTATLALPGGGGITSTLS 464
Reeler_cohesin_like super family cl14606
Domains similar to the eukaryotic reeler domain and bacterial cohesins; This diverse family ...
39-102 2.43e-03

Domains similar to the eukaryotic reeler domain and bacterial cohesins; This diverse family summarizes a set of distantly related domains, as revealed by structural similarity


The actual alignment was detected with superfamily member cd08547:

Pssm-ID: 472692  Cd Length: 136  Bit Score: 38.54  E-value: 2.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1707074376  39 GVRGFLLEARYDPAALRYLGAE------GGFLLESYAPEPGRLRLAGVSYTPQ-----SGEVLRLRFQALRPGAS 102
Cdd:cd08547    29 NLAGYDFTLSYDPSVLEFVSVTtgslsgGGGVIANEDAPPGTVRVAGSSTGGAggvsgSGTLATLTFKAKAAGTS 103
 
Name Accession Description Interval E-value
YfaP COG4676
Uncharacterized conserved protein YfaP, DUF2135 family [Function unknown];
507-599 2.09e-14

Uncharacterized conserved protein YfaP, DUF2135 family [Function unknown];


Pssm-ID: 443712  Cd Length: 125  Bit Score: 70.01  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 507 RVVLSW-TSGADLDLHLFYPDtpaAHHVYWQNPgvCPPAGEAcLEGDTLQGPGQEALRFTS-TGGSYRVYVHwYFGGGSW 584
Cdd:COG4676     9 RVVLTWdTDPADLDLHVVEPD---GEHVYYGNK--LTPNGGR-LDVDDTDGYGPEEFTIRKaPPGTYLVNVN-YYGNGGQ 81
                          90
                  ....*....|....*.
gi 1707074376 585 ATAGAQVQVF-NAGYP 599
Cdd:COG4676    82 APTTAKVTVYtNYGTP 97
COG1470 COG1470
Uncharacterized membrane protein [Function unknown];
210-647 1.68e-06

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 441079 [Multi-domain]  Cd Length: 475  Bit Score: 51.01  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 210 VNPSLGAGLEVAPLRLALNPGESAYVLVGNSGNEPLPPLVLEAAPGLSVAEETPSGYAGRVYRVAASQSVSQGALLFRAG 289
Cdd:COG1470     3 AAGLVASSTVAAGALAALLDLTTPLVGSTVALTSTASALSGERTTLAALAATGGLVTATPVSPTSATLTLSVEVPSNATV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 290 NQARAVAVNGTAPDFLLGL-SGTPTGPVGGTAQATLTLTPLNGFTGTVSLSLVDPPAGVSLSPAG---LIVSGPDPVDLP 365
Cdd:COG1470    83 GTYLPITVTVAPYGLTLSVeSPSLEVAPGETVTYTVTLTNTGDEPDTVSLSAEGLPEGWTVTFTPdtsVSLAPGESKTVT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 366 LTLTLDPGLAPQDYPLTLRASGGSRTREVQFTLKAT-----DFALAGSPA-LTLPWGGMGSLGVAVLPQNGFATPLNLAL 439
Cdd:COG1470   163 LEVTPPANAEPGTYPVTVTATSGEDSSSASLTLTLTvtgsyELELSSTPTgRTVTPGESATFTVTVTNTGNGADLTNVTL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 440 KrqdgTPLPPGLALT-----TPTLPPSG-GPVGLQVQNP---PPGDYPLRLEATpqgGGATRSLDFTLTVTYSPEWRVV- 509
Cdd:COG1470   243 S----ASAPSGWTVSfepetIPSLAPGEsATVTLTVTVPadaTAGDYTVTVTAT---SDETASATLRLTVETSSLWGWIg 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 510 --------LSWTSGADLDLHLFYPDTPAAHHVYWQNPGVCPPAGEACLEGDTLQGPGQEALRFTSTGGSYRVYVHWYFGG 581
Cdd:COG1470   316 ylirkyggLGATGSLLVASVSLVVGAVVGTLTTPLLLTGFAGNGLLSAATAPLLLLLGLTLSLLSDVLVFTVGSAGVSAA 395
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1707074376 582 GSWATAGAQVQVFNAGYP---VGSFPAPGDPGGYGTWWHVLTVGPGGLEAGSGVAGIAPQGGLTPLGLP 647
Cdd:COG1470   396 AATAETSALTALGVGATGavgSGSASASVKVTGGAAVATGLTDATTLPGAGSTATLALPGGGGITSTLS 464
Type_II_cohesin cd08547
Type II cohesin domain, interaction partner of dockerin; Bacterial cohesin domains bind to a ...
39-102 2.43e-03

Type II cohesin domain, interaction partner of dockerin; Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II cohesins; their interactions with dockerin mediate attachment of the cellulosome complex to the bacterial cell wall.


Pssm-ID: 260084  Cd Length: 136  Bit Score: 38.54  E-value: 2.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1707074376  39 GVRGFLLEARYDPAALRYLGAE------GGFLLESYAPEPGRLRLAGVSYTPQ-----SGEVLRLRFQALRPGAS 102
Cdd:cd08547    29 NLAGYDFTLSYDPSVLEFVSVTtgslsgGGGVIANEDAPPGTVRVAGSSTGGAggvsgSGTLATLTFKAKAAGTS 103
 
Name Accession Description Interval E-value
YfaP COG4676
Uncharacterized conserved protein YfaP, DUF2135 family [Function unknown];
507-599 2.09e-14

Uncharacterized conserved protein YfaP, DUF2135 family [Function unknown];


Pssm-ID: 443712  Cd Length: 125  Bit Score: 70.01  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 507 RVVLSW-TSGADLDLHLFYPDtpaAHHVYWQNPgvCPPAGEAcLEGDTLQGPGQEALRFTS-TGGSYRVYVHwYFGGGSW 584
Cdd:COG4676     9 RVVLTWdTDPADLDLHVVEPD---GEHVYYGNK--LTPNGGR-LDVDDTDGYGPEEFTIRKaPPGTYLVNVN-YYGNGGQ 81
                          90
                  ....*....|....*.
gi 1707074376 585 ATAGAQVQVF-NAGYP 599
Cdd:COG4676    82 APTTAKVTVYtNYGTP 97
COG1470 COG1470
Uncharacterized membrane protein [Function unknown];
210-647 1.68e-06

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 441079 [Multi-domain]  Cd Length: 475  Bit Score: 51.01  E-value: 1.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 210 VNPSLGAGLEVAPLRLALNPGESAYVLVGNSGNEPLPPLVLEAAPGLSVAEETPSGYAGRVYRVAASQSVSQGALLFRAG 289
Cdd:COG1470     3 AAGLVASSTVAAGALAALLDLTTPLVGSTVALTSTASALSGERTTLAALAATGGLVTATPVSPTSATLTLSVEVPSNATV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 290 NQARAVAVNGTAPDFLLGL-SGTPTGPVGGTAQATLTLTPLNGFTGTVSLSLVDPPAGVSLSPAG---LIVSGPDPVDLP 365
Cdd:COG1470    83 GTYLPITVTVAPYGLTLSVeSPSLEVAPGETVTYTVTLTNTGDEPDTVSLSAEGLPEGWTVTFTPdtsVSLAPGESKTVT 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 366 LTLTLDPGLAPQDYPLTLRASGGSRTREVQFTLKAT-----DFALAGSPA-LTLPWGGMGSLGVAVLPQNGFATPLNLAL 439
Cdd:COG1470   163 LEVTPPANAEPGTYPVTVTATSGEDSSSASLTLTLTvtgsyELELSSTPTgRTVTPGESATFTVTVTNTGNGADLTNVTL 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 440 KrqdgTPLPPGLALT-----TPTLPPSG-GPVGLQVQNP---PPGDYPLRLEATpqgGGATRSLDFTLTVTYSPEWRVV- 509
Cdd:COG1470   243 S----ASAPSGWTVSfepetIPSLAPGEsATVTLTVTVPadaTAGDYTVTVTAT---SDETASATLRLTVETSSLWGWIg 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1707074376 510 --------LSWTSGADLDLHLFYPDTPAAHHVYWQNPGVCPPAGEACLEGDTLQGPGQEALRFTSTGGSYRVYVHWYFGG 581
Cdd:COG1470   316 ylirkyggLGATGSLLVASVSLVVGAVVGTLTTPLLLTGFAGNGLLSAATAPLLLLLGLTLSLLSDVLVFTVGSAGVSAA 395
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1707074376 582 GSWATAGAQVQVFNAGYP---VGSFPAPGDPGGYGTWWHVLTVGPGGLEAGSGVAGIAPQGGLTPLGLP 647
Cdd:COG1470   396 AATAETSALTALGVGATGavgSGSASASVKVTGGAAVATGLTDATTLPGAGSTATLALPGGGGITSTLS 464
Type_II_cohesin cd08547
Type II cohesin domain, interaction partner of dockerin; Bacterial cohesin domains bind to a ...
39-102 2.43e-03

Type II cohesin domain, interaction partner of dockerin; Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II cohesins; their interactions with dockerin mediate attachment of the cellulosome complex to the bacterial cell wall.


Pssm-ID: 260084  Cd Length: 136  Bit Score: 38.54  E-value: 2.43e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1707074376  39 GVRGFLLEARYDPAALRYLGAE------GGFLLESYAPEPGRLRLAGVSYTPQ-----SGEVLRLRFQALRPGAS 102
Cdd:cd08547    29 NLAGYDFTLSYDPSVLEFVSVTtgslsgGGGVIANEDAPPGTVRVAGSSTGGAggvsgSGTLATLTFKAKAAGTS 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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