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Conserved domains on  [gi|1706865978|ref|NP_001358537|]
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CB1 cannabinoid receptor-interacting protein 1 isoform 3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CNRIP1 super family cl20916
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 26-129 7.06e-56

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


The actual alignment was detected with superfamily member pfam15043:

Pssm-ID: 464465  Cd Length: 152  Bit Score: 171.34  E-value: 7.06e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706865978  26 PPTRLRNISIGGVLVPLELKSKepDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHC 105
Cdd:pfam15043  51 PALELTSLSIGGVSLELEEKSR--DEEAVVYSGEWSTEGVAVSKSGDRQPVQISMQFNPGGTLTTVLQVKFYRYNDTDHC 128

                          90       100
                  ....*....|....*....|....
gi 1706865978 106 QWGSPFSVIEYECKPNETRSLMWV 129
Cdd:pfam15043 129 QWGNPLNSIEYECKLDEGRSLVKI 152
 
Name Accession Description Interval E-value
CNRIP1 pfam15043
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 26-129 7.06e-56

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


Pssm-ID: 464465  Cd Length: 152  Bit Score: 171.34  E-value: 7.06e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706865978  26 PPTRLRNISIGGVLVPLELKSKepDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHC 105
Cdd:pfam15043  51 PALELTSLSIGGVSLELEEKSR--DEEAVVYSGEWSTEGVAVSKSGDRQPVQISMQFNPGGTLTTVLQVKFYRYNDTDHC 128

                          90       100
                  ....*....|....*....|....
gi 1706865978 106 QWGSPFSVIEYECKPNETRSLMWV 129
Cdd:pfam15043 129 QWGNPLNSIEYECKLDEGRSLVKI 152
 
Name Accession Description Interval E-value
CNRIP1 pfam15043
CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with ...
 26-129 7.06e-56

CB1 cannabinoid receptor-interacting protein 1; This family of proteins interacts with cannabinoid receptor 1 (CNR1) and attenuates CNR1-mediated tonic inhibition of voltage-gated calcium channels.


Pssm-ID: 464465  Cd Length: 152  Bit Score: 171.34  E-value: 7.06e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706865978  26 PPTRLRNISIGGVLVPLELKSKepDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHC 105
Cdd:pfam15043  51 PALELTSLSIGGVSLELEEKSR--DEEAVVYSGEWSTEGVAVSKSGDRQPVQISMQFNPGGTLTTVLQVKFYRYNDTDHC 128

                          90       100
                  ....*....|....*....|....
gi 1706865978 106 QWGSPFSVIEYECKPNETRSLMWV 129
Cdd:pfam15043 129 QWGNPLNSIEYECKLDEGRSLVKI 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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