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Conserved domains on  [gi|170657519|gb|ACB26574|]
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two component transcriptional regulator, LuxR family [Methylobacterium radiotolerans JCM 2831]

Protein Classification

response regulator transcription factor( domain architecture ID 11450879)

response regulator transcription factor with a signal receiver (REC) domain and a LuxR family helix-turn-helix (HTH) domain that may be part of a two-component regulatory system; similar to Staphylococcus aureus response regulator VraR

CATH:  1.10.10.10
Gene Ontology:  GO:0000160|GO:0006355|GO:0003677
PubMed:  10966457
SCOP:  3001179

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10651 super family cl32550
transcriptional regulator NarL; Provisional
 132-253 3.32e-17

transcriptional regulator NarL; Provisional


The actual alignment was detected with superfamily member PRK10651:

Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 78.15  E-value: 3.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 132 ISDGEnlDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYIPaECLLPLLANiKVDEPVEAGDDDI--FSPRQLCV 209
Cdd:PRK10651  88 VSNHE--EDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLS-EALTPVLAA-SLRANRATTERDVnqLTPRERDI 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 170657519 210 ARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:PRK10651 164 LKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAA 207
AmiR super family cl34660
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 45-171 1.09e-03

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


The actual alignment was detected with superfamily member COG3707:

Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 39.17  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519  45 RSSRIVIIDRRQLVGRCLAASLSEADRQTSFEVFADIESWKRQKPFVPASVVVLCRPDGnltetewtEITRELAFLQGEA 124
Cdd:COG3707    2 RGLRVLVVDDEPLRRADLREGLREAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPD--------RDGLEAARQISEE 73

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 170657519 125 GAPPVAVISDGENLDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQA 171
Cdd:COG3707   74 RPAPVILLTAYSDPELIERALEAGVSAYLVKPLDPEDLLPALELALA 120
 
Name Accession Description Interval E-value
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 132-253 3.32e-17

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 78.15  E-value: 3.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 132 ISDGEnlDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYIPaECLLPLLANiKVDEPVEAGDDDI--FSPRQLCV 209
Cdd:PRK10651  88 VSNHE--EDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLS-EALTPVLAA-SLRANRATTERDVnqLTPRERDI 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 170657519 210 ARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:PRK10651 164 LKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAA 207
GerE pfam00196
Bacterial regulatory proteins, luxR family;
200-253 6.45e-15

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 67.61  E-value: 6.45e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 170657519  200 DIFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELV 54
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 199-251 1.21e-14

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 66.78  E-value: 1.21e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 170657519   199 DDIFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQ 53
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 201-253 3.01e-13

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 65.30  E-value: 3.01e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 170657519 201 IFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:COG2197   69 LLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELV 121
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 202-251 1.51e-12

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 61.01  E-value: 1.51e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 170657519 202 FSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:cd06170    1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQ 50
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 45-171 1.09e-03

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 39.17  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519  45 RSSRIVIIDRRQLVGRCLAASLSEADRQTSFEVFADIESWKRQKPFVPASVVVLCRPDGnltetewtEITRELAFLQGEA 124
Cdd:COG3707    2 RGLRVLVVDDEPLRRADLREGLREAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPD--------RDGLEAARQISEE 73

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 170657519 125 GAPPVAVISDGENLDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQA 171
Cdd:COG3707   74 RPAPVILLTAYSDPELIERALEAGVSAYLVKPLDPEDLLPALELALA 120
 
Name Accession Description Interval E-value
PRK10651 PRK10651
transcriptional regulator NarL; Provisional
 132-253 3.32e-17

transcriptional regulator NarL; Provisional


Pssm-ID: 182619 [Multi-domain]  Cd Length: 216  Bit Score: 78.15  E-value: 3.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 132 ISDGEnlDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYIPaECLLPLLANiKVDEPVEAGDDDI--FSPRQLCV 209
Cdd:PRK10651  88 VSNHE--EDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLS-EALTPVLAA-SLRANRATTERDVnqLTPRERDI 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 170657519 210 ARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:PRK10651 164 LKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAA 207
GerE pfam00196
Bacterial regulatory proteins, luxR family;
200-253 6.45e-15

Bacterial regulatory proteins, luxR family;


Pssm-ID: 425517 [Multi-domain]  Cd Length: 57  Bit Score: 67.61  E-value: 6.45e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 170657519  200 DIFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:pfam00196   1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVELV 54
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 199-251 1.21e-14

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 66.78  E-value: 1.21e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 170657519   199 DDIFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:smart00421   1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQ 53
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 201-253 3.01e-13

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 65.30  E-value: 3.01e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 170657519 201 IFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:COG2197   69 LLTPREREVLRLLAEGLSNKEIAERLGISERTVKTHVSNILRKLGVRNRTELV 121
LuxR_C_like cd06170
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ...
 202-251 1.51e-12

C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.


Pssm-ID: 99777 [Multi-domain]  Cd Length: 57  Bit Score: 61.01  E-value: 1.51e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 170657519 202 FSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:cd06170    1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQ 50
PRK10360 PRK10360
transcriptional regulator UhpA;
49-254 2.45e-11

transcriptional regulator UhpA;


Pssm-ID: 182408 [Multi-domain]  Cd Length: 196  Bit Score: 61.53  E-value: 2.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519  49 IVIIDRRQLVGRCLAASLS-EADrqtsFEVFADIESWKRQKPFVPASVVVLCRPDGNLTETEWTEITRELAflQGEAgap 127
Cdd:PRK10360   4 VALIDDHLIVRSGFAQLLGlEPD----LQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLP--KGMA--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 128 pVAVISDGENLDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYIPAECLLPLlanikvdepvEAGDDDIFSPRQL 207
Cdd:PRK10360  75 -TIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKL----------ASGRQDPLTKRER 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 170657519 208 CVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVAY 254
Cdd:PRK10360 144 QVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELAR 190
GerE COG5905
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ...
 200-253 5.65e-11

Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];


Pssm-ID: 444607 [Multi-domain]  Cd Length: 76  Bit Score: 57.28  E-value: 5.65e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 170657519 200 DIFSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVA 253
Cdd:COG5905   11 SLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNRVQAV 64
PRK15369 PRK15369
two component system response regulator;
142-251 2.49e-09

two component system response regulator;


Pssm-ID: 185267 [Multi-domain]  Cd Length: 211  Bit Score: 55.86  E-value: 2.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 142 VRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYI-PAECLLPLLANIKVDEpveaGDDDIFSPRQLCVARALRKGTPNK 220
Cdd:PRK15369  93 SRTLAAGALGYVLKKSPQQILLAAIQTVAVGKRYIdPALNREAILALLNADD----TNPPLLTPRERQILKLITEGYTNR 168

                         90       100       110
                 ....*....|....*....|....*....|.
gi 170657519 221 IIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:PRK15369 169 DIAEQLSISIKTVETHRLNMMRKLDVHKVAE 199
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
202-261 5.53e-09

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 54.76  E-value: 5.53e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170657519 202 FSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE-VAYLTNKYFL 261
Cdd:COG2771  128 LTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRKLGVSSRAElVALALRLGLI 188
PRK10403 PRK10403
nitrate/nitrite response regulator protein NarP;
129-249 2.77e-08

nitrate/nitrite response regulator protein NarP;


Pssm-ID: 182431 [Multi-domain]  Cd Length: 215  Bit Score: 52.93  E-value: 2.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519 129 VAVISDGENldQIVRIIKLGVKGYIPTTTSVDIALQALQLVQAGGVYIPAECLLPLLANikvdEPVEAGDD--DIFSPRQ 206
Cdd:PRK10403  85 ILTVSDASS--DVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLRER----EMFGAEEDpfSVLTERE 158

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 170657519 207 LCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNR 249
Cdd:PRK10403 159 LDVLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSR 201
FixJ COG4566
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ...
 203-248 5.90e-08

DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 443623 [Multi-domain]  Cd Length: 196  Bit Score: 51.64  E-value: 5.90e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 170657519 203 SPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKN 248
Cdd:COG4566  139 TPREREVLDLVVAGLSNKQIARELGISPRTVEVHRANVMEKLGARS 184
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
205-251 1.17e-06

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 47.78  E-value: 1.17e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 170657519 205 RQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTE 251
Cdd:COG2909  126 LAALRRRLLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTE 172
fixJ PRK09390
response regulator FixJ; Provisional
 185-256 2.05e-06

response regulator FixJ; Provisional


Pssm-ID: 181815 [Multi-domain]  Cd Length: 202  Bit Score: 47.30  E-value: 2.05e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 170657519 185 LANIKVDEPVEAGDDDI------FSPRQLCVARALRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVAYLT 256
Cdd:PRK09390 119 LAQAPEAAKSEAVAADIrariasLSERERQVMDGLVAGLSNKVIARDLDISPRTVEVYRANVMTKMQAGSLSELVRMA 196
PRK10100 PRK10100
transcriptional regulator CsgD;
213-262 6.43e-05

transcriptional regulator CsgD;


Pssm-ID: 182241 [Multi-domain]  Cd Length: 216  Bit Score: 42.94  E-value: 6.43e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 170657519 213 LRKGTPNKIIAYELNMCESTVKVHVRNIMKKLKAKNRTEVAYLTNKYFLR 262
Cdd:PRK10100 167 LRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR 216
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 45-171 1.09e-03

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 39.17  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170657519  45 RSSRIVIIDRRQLVGRCLAASLSEADRQTSFEVFADIESWKRQKPFVPASVVVLCRPDGnltetewtEITRELAFLQGEA 124
Cdd:COG3707    2 RGLRVLVVDDEPLRRADLREGLREAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPD--------RDGLEAARQISEE 73

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 170657519 125 GAPPVAVISDGENLDQIVRIIKLGVKGYIPTTTSVDIALQALQLVQA 171
Cdd:COG3707   74 RPAPVILLTAYSDPELIERALEAGVSAYLVKPLDPEDLLPALELALA 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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