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Conserved domains on  [gi|170026943|gb|ACB05998|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Sousa chinensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-168

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 472.79  E-value: 1.52e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 170026943 321 KQMTLLPTAIVLSTMLLPLTPAFFIL 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-168

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 472.79  E-value: 1.52e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 170026943 321 KQMTLLPTAIVLSTMLLPLTPAFFIL 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 5.11e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 107.78  E-value: 5.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   23 SSHWLFAWIGLEMNMMAIIPIM-MKKPNPRATEASAKYFLTQTTASSLLMLAIII--NLMHSSQWTIMKLFDPT------ 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmyNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   94 ---ASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILL-TWQKLAPISI-----LYQISPSINLHLMITMSFLSILI 164
Cdd:pfam00361  81 lllLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  165 GGWGGLNQTQLRKIMAYSSIAHMGWMTTILL----YNPTLTLLNLLIYIVMTFTMF-----MLLIQNSTTTTLLLSQTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 170026943  236 TVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-296 6.02e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 107.89  E-value: 6.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMnmMAI---IPIMMKKPNPRATEASAKYFLTQTTASSLLML---------------AIIINLMHSSQW 84
Cdd:COG1007  121 ANDLLTLFLGLEL--LSLslyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgslnlaGIAAALAAGGAN 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  85 TIMKLFdptASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQI------SPSINLHLMIT-M 157
Cdd:COG1007  199 SPLLLL---GLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpGLAADWQLLLAvL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 158 SFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM------------TTILLYNPtltllnllIYIVMTFTMFMLLIQNSTT 225
Cdd:COG1007  276 AVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLllglaagtplgvSAALFYLL--------AYLFMNLGAFAVILLLSRK 347

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170026943 226 TTLLLSQT-----WNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:COG1007  348 GGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 22-296 1.42e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 92.32  E-value: 1.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   22 ISSHWLFAWIGLEMNMMAI-IPIMMKKPNPRATEASAKYFLTQTTASSLLMLAI--------------IINLMHSSQWTI 86
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGIsliygftgslnfedLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   87 MKLFdpTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSI------NLHLMI-TMSF 159
Cdd:TIGR01770 200 SLLL--LGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseAWQIFLaIIAF 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  160 LSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTL----TLLNLLIYIVMTFTMFMLLI------QNSTTTTLL 229
Cdd:TIGR01770 278 LSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSllrsykDEWIEYISD 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170026943  230 LSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:TIGR01770 358 FAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 1.52e-168

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 472.79  E-value: 1.52e-168
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*.
gi 170026943 321 KQMTLLPTAIVLSTMLLPLTPAFFIL 346
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 23-347 7.13e-126

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 364.90  E-value: 7.13e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTIMKLFDPTASILMTMAL 102
Cdd:MTH00135  23 SSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 103 AIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSiNLHLMITMSFLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:MTH00135 103 ALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQTQLRKILAYS 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 183 SIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMP 262
Cdd:MTH00135 182 SIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMP 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 263 KWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPTKQMTLLPTAIVLSTMLLPLTPA 342
Cdd:MTH00135 262 KWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTTATLMLLPLTPA 341


                 ....*
gi 170026943 343 FFILL 347
Cdd:MTH00135 342 ILALL 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-341 1.24e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 338.72  E-value: 1.24e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFyPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRT-KP 319

                        330       340
                 ....*....|....*....|.
gi 170026943 321 KQMTLLPTAIVLSTMLLPLTP 341
Cdd:MTH00112 320 KKNTLTATLTTLSTLLLPLSP 340
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-347 4.14e-114

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 334.97  E-value: 4.14e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFyPT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 170026943 321 KQMTLLPTAIVLSTMLLPLTPAFFILL 347
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 20-306 2.00e-85

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 261.79  E-value: 2.00e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  20 VTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTIMKLFDPTASILMT 99
Cdd:MTH00041  20 VISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIIT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 100 MALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFLSILIGGWGGLNQTQLRKIM 179
Cdd:MTH00041 100 LALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKIL 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 180 AYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTG 259
Cdd:MTH00041 180 AFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTG 259

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 170026943 260 FMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFP 306
Cdd:MTH00041 260 FLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFP 306
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 2.27e-83

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 256.43  E-value: 2.27e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   1 MNPFISITLLTTLILSTTIVTISSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMH 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  81 SSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 161 SILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIM 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPT 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*..
gi 170026943 321 KQMtLLPTAIVLSTMLLPLTPAFFILL 347
Cdd:MTH00200 321 SNL-LVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 23-315 1.96e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 176.23  E-value: 1.96e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTIMklfdptasILMTMAL 102
Cdd:MTH00144  23 SSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM--------SLLLLGL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 103 AIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINL-HLMITMSFLSILIGGWGGLNQTQLRKIMAY 181
Cdd:MTH00144  95 CLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLNQTQVRALLAY 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 182 SSIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTwNTVPIMTTFTMLTLLSMGGLPPLTGFM 261
Cdd:MTH00144 175 SSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSLGGLPPFLGFC 253

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 170026943 262 PKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKW 315
Cdd:MTH00144 254 SKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 23-346 2.71e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 170.77  E-value: 2.71e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMhssqwtIMKLFDPTASILMTMAL 102
Cdd:MTH00160  24 SNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NLMLFNNISSMLINSSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 103 AIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQIspsINLHLMITMSFLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:MTH00160  98 LLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIGAIGGLNQTSLRKILAYS 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 183 SIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMP 262
Cdd:MTH00160 175 SINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLP 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 263 KWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYStalTLFPSTNNMKMKWQFYPTKQMTLLPTAIVLSTMLLPLTPA 342
Cdd:MTH00160 255 KWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS---SLMLNYNKNKWNLKKKKNKFSLILNFLSFISLFGLILSSL 331


                 ....
gi 170026943 343 FFIL 346
Cdd:MTH00160 332 LFLL 335
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 23-299 5.52e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 156.86  E-value: 5.52e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTImklfdpTASILMTMAL 102
Cdd:MTH00011  25 SNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLKN------ITALMLLVSL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 103 AIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:MTH00011  99 MLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYS 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 183 SIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMP 262
Cdd:MTH00011 179 SIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMP 258

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 170026943 263 KWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYS 299
Cdd:MTH00011 259 KLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 23-321 1.40e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 137.11  E-value: 1.40e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLmlaiiinLMHSSQWTIMKLFDPTASILMTMAL 102
Cdd:MTH00197  17 SSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALL-------LMGGSLSFSNLYLSLLSVVLVILGL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 103 AIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMitMSFLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:MTH00197  90 LLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLI--CSVLSSLIGGIGGMNQSNIRQLLAYS 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 183 SIAHMGWMTTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMP 262
Cdd:MTH00197 168 SIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 170026943 263 KWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFYPTK 321
Cdd:MTH00197 248 KWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGL 306
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 5.11e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 107.78  E-value: 5.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   23 SSHWLFAWIGLEMNMMAIIPIM-MKKPNPRATEASAKYFLTQTTASSLLMLAIII--NLMHSSQWTIMKLFDPT------ 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmyNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   94 ---ASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILL-TWQKLAPISI-----LYQISPSINLHLMITMSFLSILI 164
Cdd:pfam00361  81 lllLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  165 GGWGGLNQTQLRKIMAYSSIAHMGWMTTILL----YNPTLTLLNLLIYIVMTFTMF-----MLLIQNSTTTTLLLSQTWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFlcagsVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 170026943  236 TVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 23-296 1.38e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 108.19  E-value: 1.38e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMNMMAI-IPIMMKKPNPRATEASAKYFLTQTTASSLLMLAI-------------IINLMHSSQWTIMK 88
Cdd:MTH00196  12 SSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCallcgttgglhlsYINLVLNSGQSFSS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  89 LFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMsfLSILIGGWG 168
Cdd:MTH00196  92 VSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGL--FSLFVGAIG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 169 GLNQTQLRKIMAYSSIAHMGWMTTIL----LYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLL--SQTWNTVPIMTT 242
Cdd:MTH00196 170 ALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIIefSGLSRRLPILAI 249

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 170026943 243 FTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:MTH00196 250 TLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-296 6.02e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 107.89  E-value: 6.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEMnmMAI---IPIMMKKPNPRATEASAKYFLTQTTASSLLML---------------AIIINLMHSSQW 84
Cdd:COG1007  121 ANDLLTLFLGLEL--LSLslyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgslnlaGIAAALAAGGAN 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  85 TIMKLFdptASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQI------SPSINLHLMIT-M 157
Cdd:COG1007  199 SPLLLL---GLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpGLAADWQLLLAvL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 158 SFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM------------TTILLYNPtltllnllIYIVMTFTMFMLLIQNSTT 225
Cdd:COG1007  276 AVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLllglaagtplgvSAALFYLL--------AYLFMNLGAFAVILLLSRK 347

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170026943 226 TTLLLSQT-----WNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:COG1007  348 GGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 23-296 9.82e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 104.33  E-value: 9.82e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLEM-NMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTIMK----LFDPTASIL 97
Cdd:MTH00199 116 SINWLSIYLAIELqTLTLFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGinsiLTGDVGKIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  98 MTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMsfLSILIGGWGGLNQTQLRK 177
Cdd:MTH00199 196 ITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAV--LSIIYGAIGALNQTKIKR 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 178 IMAYSSIAHMGWMTTILLY----NPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLL--LSQTWNTVPIMTTFTMLTLLSM 251
Cdd:MTH00199 274 LLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSICSFSIILSLKLTKGLIveVSGLSRKNPVIALTLALTFLSI 353

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 170026943 252 GGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:MTH00199 354 AGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 22-296 1.42e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 92.32  E-value: 1.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   22 ISSHWLFAWIGLEMNMMAI-IPIMMKKPNPRATEASAKYFLTQTTASSLLMLAI--------------IINLMHSSQWTI 86
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGIsliygftgslnfedLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   87 MKLFdpTASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSI------NLHLMI-TMSF 159
Cdd:TIGR01770 200 SLLL--LGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseAWQIFLaIIAF 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  160 LSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTL----TLLNLLIYIVMTFTMFMLLI------QNSTTTTLL 229
Cdd:TIGR01770 278 LSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSllrsykDEWIEYISD 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170026943  230 LSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:TIGR01770 358 FAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
23-296 8.51e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 89.88  E-value: 8.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  23 SSHWLFAWIGLE-MNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLML---------------AIIINLMHSSQWTI 86
Cdd:PRK05777 122 ANDLLTLFLGLElLSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatgslsfaGIAKALADGSGNSL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  87 MKLFdptASILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPIS----ILYQISPSINLH---LMITMSF 159
Cdd:PRK05777 202 LLLF---GLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAvllrLLVVAFGGLSEDwqqVLAIIAI 278

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 160 LSILIGGWGGLNQTQLRKIMAYSSIAHMGWM------------TTILLYnptltllnLLIYIVMT---FTMFMLLIQNST 224
Cdd:PRK05777 279 ASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglaagtaegySAVLFY--------LLAYLFMTlgaFGVISLLRRKGG 350

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 170026943 225 TTTLLLSqtWN----TVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:PRK05777 351 EAESISD--FAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-296 6.05e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 75.18  E-value: 6.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  30 WIGLEMNMMAIIPIMMKKPNPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTI------MKLFDP----TASILMT 99
Cdd:COG0651  133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMadlaarLAELDPglllAAFALLL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 100 MALAIKLGLSPFHFWVPE-----------VTQGIPLSTGL--ILLTWQKLAPISILYQISPsinlhLMITMSFLSILIGG 166
Cdd:COG0651  213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGT-----LLLVLGLLTMLVGA 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 167 WGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIV----MTFTMFM----LLIQNSTTTTLLLSQTWNTVP 238
Cdd:COG0651  288 LGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhalAKALLFLaagaIERATGTRDLDKLGGLGKRMP 367

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 170026943 239 IMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:COG0651  368 LTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 96-267 8.13e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.04  E-value: 8.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  96 ILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILyqISPSINLHLMITMSFLSILIGGWGGLNQTQL 175
Cdd:MTH00198 303 LFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITSKLLLSVAIISLVVGAFGALNQTRI 380

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 176 RKIMAYSSIAHMGWM----TTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQT--------WNTVPIMTTF 243
Cdd:MTH00198 381 KRLLAYSGIGHIGFIligvSAGTYESLQASWTYAVTYLVSALASFTVICTLEEFGTRTPTSRqrdgsfgnYNLVRRLVDL 460

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 170026943 244 TMLT-------------LLSMGGLPPLTGFMPKWMII 267
Cdd:MTH00198 461 TILSrgqpyiafslaivFLSLAGIPPLLGFLGKWFIL 497
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 8.82e-12

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 59.19  E-value: 8.82e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 170026943  291 YFYMRLTYSTALTLFPSTNNMKMKWQFYPTKQMTLLPTAIVLSTMLLPLTP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 50-299 1.09e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 59.34  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  50 PRATEASAKYFLTQTTASSLLMLAIII-----NLMHSSQWTIMKLFDPT-----ASILMTMALAIKLGLSPFHFWVPEVT 119
Cdd:PRK08376 168 WEAIEAGIKYMFVGSLASSMVLLGIALlygqyGTLNMAYLAVKMSENPTvvakiALALFIAGLAMKSGAVPVHMWLPDAY 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 120 QGIPLSTGLILLTwQKLAPISILYQIS-----PSINLH----LMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK08376 248 PAAPSSISAMLLV-IKQAGLYALARVLfsiygPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYM 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 191 -----------TTILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWN---------TVPIMTTFTMLTLLS 250
Cdd:PRK08376 327 llglgvglaalGDPAMASYGEIALAGGIYHIVNHALYKALLFLTAGAVIYETGTRNlnelgglarTMPKTTIAFLIGAAA 406

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 170026943 251 MGGLPPLTGFMPKWMIIqELTKNKTLILPTLMAITALLNLYFYMRLTYS 299
Cdd:PRK08376 407 IVGLPPFNGFASKWLIY-ESSALFNPILGVIAMIGSVLTLASFVKVFHT 454
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-295 8.20e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.60  E-value: 8.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  47 KPNPRATEASAKYFLTQTTAS-------SLL--------MLAIIINLMHSSQWTIMKLfdptASILMTMALAIKLGLSPF 111
Cdd:PRK02504 154 KRDPRSNEAALKYLLIGAASSaiflygsSLLyglsggstQLSAIALALITSPSLGLAL----ALVFVIAGIAFKISAVPF 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 112 HFWVPEVTQGIPLSTGLILLTWQKLA----PISILYQISPSIN--LHLMIT-MSFLSILIGGWGGLNQTQLRKIMAYSSI 184
Cdd:PRK02504 230 HQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDeqWKLLFTaLAILSMVLGNVVALAQTSMKRMLAYSSI 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 185 AHMGWM------------TTILLYNPtltllnllIYIVMTFTMFMLLIQNSTTT----TLLLSQTWNTVPIMTTFTMLTL 248
Cdd:PRK02504 310 GQAGFVmiglvagteagyASMVFYLL--------AYLFMNLGAFACVILFSLRTgtdqISDYAGLYQKDPLLTLGLSLCL 381

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 170026943 249 LSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMR 295
Cdd:PRK02504 382 LSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-296 2.18e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 52.31  E-value: 2.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  51 RATEASAKYFLTQTTASSLLM---------------LAIIINLMHSSQwtimkLFDPTAS----ILMTMALAIKLGLSPF 111
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVygfswlyglsggeieLQEIVNGLINTQ-----MYNSPGIsialIFITVGIGFKLSLAPF 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 112 HFWVPEVTQGIPLSTGLILLTWQKLAPIS--------ILYQISPSINLHLMItMSFLSILIGGWGGLNQTQLRKIMAYSS 183
Cdd:CHL00049 234 HQWTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFYFSSNEWHLLLEI-LAILSMILGNLIAITQTSMKRMLAYSS 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 184 IAHMGWMTTILLYNPT-----LTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWNTV----PIMTTFTMLTLLSMGGL 254
Cdd:CHL00049 313 IGQIGYVIIGIIVGDSndgyaSMITYMLFYIFMNLGTFACIVLFGLRTGTDNIRDYAGLytkdPFLALSLALCLLSLGGI 392

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 170026943 255 PPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:CHL00049 393 PPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12650 PRK12650
DUF4040 family protein;
78-263 2.62e-07

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 52.35  E-value: 2.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  78 LMHSSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGI-PLSTGLILLTWQKlAPISILYQISP-----SINL 151
Cdd:PRK12650 194 ILHSDVWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMAAItPVSAFLHAAAVVK-AGIYLLLRFSPvfhdvAVWN 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 152 HLMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM-TTILL---YNPTLTLLNLLIYIVMTFTMFMLL----IQNS 223
Cdd:PRK12650 273 WLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIvATIGVgtpFALTAAVVHTLAHALFKSSLFMLIgvvdHQAG 352

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 170026943 224 TTTTLLLSQTWNTVPImtTFTMLTL--LSMGGLPPLTGFMPK 263
Cdd:PRK12650 353 TRDIRRLGSLWRRMPF--TFVSVTIaaLSMAAVPPLFGFVSK 392
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-298 2.62e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 52.19  E-value: 2.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  49 NPRATEASAKYFLTQTTASSLLMLAIII--------NLMHSSQwtiMKLFDP---TASILMTMALAIKLGLSPFHFWVPE 117
Cdd:PRK08375 151 DRRALAAARKYLIVGLIGSTFLLIGVGLlygvtgtlNMADLAG---ALAENPtvvTAFGFVLLALALKAAVFPLHTWLPR 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 118 V-TQGIPLSTGLILLTWQKlAPISILYQISPSI----------NLHLMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAH 186
Cdd:PRK08375 228 AyPAAPPVVTALLSGLVTK-VAVYALIRIYFTVfggdfrfalgLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQ 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 187 MGWMTTILLYNPTLTLLNLLIYIV----MTFTMFMlliqnSTTTTLLLSQTWN---------TVPI-MTTFTMLtLLSMG 252
Cdd:PRK08375 307 MGYILLGLALLTPLALAAGLLHLLhhalMKGALFL-----AAGAIEVTYGTRRlselsglgrRMPLtAAAFAVA-SLSLI 380

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 170026943 253 GLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTY 298
Cdd:PRK08375 381 GVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-191 3.20e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 51.62  E-value: 3.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  55 ASAKYFLTqTTASSLLMLAIIINL-MHSSQWT-----IMKL-FDPTASIL----MTMALAIKLGLSPFHFWVPEVTQGIP 123
Cdd:COG1008  162 AAIKFFLY-TLAGSLLMLVAILALyFLAGALTfdiaeLAAApLPLTAQLLlflaFFIAFAVKVPMFPFHTWLPDAHVEAP 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 124 LSTGLIL---------------------LTWQKLAPIsilyqispsinlhlMITMSFLSILIGGWGGLNQTQLRKIMAYS 182
Cdd:COG1008  241 TAGSVLLagvllkmggygllrfalplfpEASAYFAPL--------------LAALGVIGIIYGALVALAQTDLKRLIAYS 306


                 ....*....
gi 170026943 183 SIAHMGWMT 191
Cdd:COG1008  307 SVSHMGFVL 315
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-268 4.00e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 51.48  E-value: 4.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943   55 ASAKYFLtQTTASSLLMLAIIINLMHSSQWT-----IMKLFDPTASILMTM-----ALAIKLGLSPFHFWVPEV-----T 119
Cdd:TIGR01972 157 AAMKFFL-YTLAGSLLMLLAILGLYFLGGGTfdlleLLNLPLPFGVQTWLFlaffiAFAVKVPLFPLHTWLPDAhveapT 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  120 QGIPLSTGLILltwqKLAP---ISILYQISPSINLHLMITMSFLS---ILIGGWGGLNQTQLRKIMAYSSIAHMGWMTTI 193
Cdd:TIGR01972 236 AGSVILAGVLL----KMGTygfLRFNLPLFPDASLYFAPVLAALGviaIIYGALIALAQTDIKRLIAYSSISHMGFVLLG 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  194 LLYNPTLTLLNLLIYIV----MTFTMFMLLIQ----NSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWM 265
Cdd:TIGR01972 312 IFSFNELGISGAVFQMIshglITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFL 391


                  ...
gi 170026943  266 IIQ 268
Cdd:TIGR01972 392 ILL 394
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 56-326 1.32e-06

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 49.92  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  56 SAKYFLTQTTASSLLMLAIIINL-----------MHSSQWTIMKLFDPTASILMTMALAIKLGLSPFHFWVPEVTQGIPL 124
Cdd:MTH00226 183 AAYYFFFYTLIGSVLMLLCLFSLynihgttdyltLASCSHVVSEQTQKWIFLGIFLAMAVKIPIFPFHIWLPKAHVEAPV 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 125 STGL----ILLTWQKLAPISILYQISPSINLHL---MITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGwMTTILLYN 197
Cdd:MTH00226 263 AGSVllagILLKLGGYGLVRLSWPILPLGAQNLapaVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMG-LVSITLVT 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 198 PTLTLLNLLIYIVMT--------FTMFMLLIQNSTTTTLLLSQTWN-TVPIMTTFTMLTLLSMGGLPPLTGFMPKWM-II 267
Cdd:MTH00226 342 HDIIGLTGSIFIMLAhgivssllFILVTILYDRHHTRLIKYYRGLSiTMPIWGTIMIVTSLANVAVPPSGNFIGEYLsIL 421

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 170026943 268 QELTKNKTL--ILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKwQFYPTKQMTLL 326
Cdd:MTH00226 422 SSFNWNPIIgvFVCSGVILSAVYSFYFANRVTFGAPGNLITFARDVNRR-EFYITASMVFF 481
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 43-299 4.31e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 48.43  E-value: 4.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  43 IMMKKPNPRATEASAKYFLTQTTASSLLMLAIII----------------NLMHSSQWTIMKLFDPTASILMTMALA--- 103
Cdd:PRK12667 153 VAYYRDRGDAVEAAIKYALIGAVGTTLYFLALAFlyatfgtlnmadlsakIRGLSFPLTGGLAGNPPLALGVALALAlwa 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 104 --IKLGLSPFHFWVPEVTQGIPLSTGLIL----LTWQKLAPISILYQI---------SPSINLHLMITMSFLSILIGGWG 168
Cdd:PRK12667 233 ftIKAAIFPNHFWLPDAHPAAPSPVSAMLsglvVNVGAYAIIRFLYTIfgispslidFRAALSPILIILGAVSAIIGALM 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 169 GLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIYIVM-TFTMFMLLIQNSTTTTLLLSQ-------TWNTVPIM 240
Cdd:PRK12667 313 MVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIINhAIAKSLLFLASGVFIHAAGTRdidelagLGRKMPIA 392

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 170026943 241 TTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYS 299
Cdd:PRK12667 393 SFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 2.11e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.96  E-value: 2.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  55 ASAKYFLtQTTASSLLMLAIIINL-------MHSSQW-TIMKL-FDPTASILMTMAL----AIKLGLSPFHFWVPEV--- 118
Cdd:PRK05846 162 AATKFFL-YTLLGSLLMLVAIIYLvvvyynaTGTFDIaDLLNLpLPPGVQYWLFLAFfiafAVKMPMFPLHTWLPDAhvq 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 119 --TQGIPLSTGLILltwqKLAP---ISILYQISPSIN---LHLMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK05846 241 apTAGSVLLAGILL----KMGAyglLRFSLPLFPDAShefAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFV 316


                 .
gi 170026943 191 T 191
Cdd:PRK05846 317 T 317
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
92-296 2.81e-05

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 45.71  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  92 PTASILMTMALAIKLGLSPFhFWVPEVTQGIPLSTGLI---LLT----WQKLAPISILYQISPSINLHLMITMSFLSILI 164
Cdd:PRK12663 207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALfaaLLTkvgiYALIRVFTLLFPQERELLHPLLATMAAITMVI 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 165 GGWGGLNQTQLRKIMAYSSIAHMGWMTTILLYNPTLTLLNLLIY-----IVMTFTMFMLLI---QNSTTTTLLLSQTWNT 236
Cdd:PRK12663 286 GALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGINGAIFYlvhdmVVKTALFLIAGSlvrLTGYRSLQYLGGLYRK 365

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 237 VPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRL 296
Cdd:PRK12663 366 EPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRI 425
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 49-300 7.05e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 44.37  E-value: 7.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  49 NPRATEASAKYFLTQTTASSLLMLAIIINLMHSSQWTIMKLF-------DPTASILMTMALAI----KLGLSPFHFWVPE 117
Cdd:COG1009  157 KPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELLaaaptilSSPLLTLILLLLLLgafgKSAQFPLHFWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 118 -----------------VTQGIPLstglilltwqkLAPISILYQISPSInLHLMITMSFLSILIGGWGGLNQTQLRKIMA 180
Cdd:COG1009  237 amegptpvsallhaatmVKAGVYL-----------LARLSPLFALSPVW-LTVVAIIGAITALFAALIALAQTDIKRVLA 304

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 181 YSSIAHMGWMTTILlynptlTLLNLLIYIVMTFT-------MFM----LLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLL 249
Cdd:COG1009  305 YSTVSQLGYMFLAL------GVGAYVAALFHLLThaffkalLFLgagsVIHATGTRDIRKMGGLRKKMPITAITFLIGAL 378

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 170026943 250 SMGGLPPLTGFMPKWMIIQEL--TKNKTLILPTLMAITALLNLYFYMRLTYST 300
Cdd:COG1009  379 SLAGIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLGAFLTAFYSFRLFFLV 431
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-191 8.87e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 44.27  E-value: 8.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 100 MALAIKLGLSPFHFWVPE-----------VTQGIPLSTG---LILLTWqKLAPISILYqISPsinlhLMITMSFLSILIG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKLGgygFIRFSW-PLLPEASEY-FSP-----LIQTLSLLAIIYG 286

                         90       100
                 ....*....|....*....|....*.
gi 170026943 166 GWGGLNQTQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00217 287 SLTTCRQVDLKRIIAYSSVAHMGLVT 312
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 56-191 1.02e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 43.90  E-value: 1.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  56 SAKYFLTQTTASSLLMLAIIINLMHSSQWT------IMKLFDPTASILMT---MALAIKLGLSPFHFWVPEVTQGIPLST 126
Cdd:MTH00204 164 ASYYFFFYTFAGSVFMLLGIFQLYSITGTTdyqillNIKLPLSIQKWLLVgffLSLAVKIPQIPFHIWLPQAHVEAPVAG 243

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170026943 127 GL----ILLTWQKLAPISILYQISPSINLH---LMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMT 191
Cdd:MTH00204 244 SVilagILLKLGGYGFLRFSWPLFPAASEYfapLIVMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVP 315
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 43-298 1.95e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.06  E-value: 1.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  43 IMMKKPNPRATEASAKYFLTQTTASSLLMLAI--------------IINLMHSSQWTIMKLFdptASILMTMALAIKLGL 108
Cdd:PRK08668 136 MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIfliyaktgtfdfadISQGLINDTSTGFALI---VFLFLLAFGVAKAGI 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 109 SPFHFWVPEVTQGIP------LSTGLI------------LLTWQKLAPISILYQISPSINlHLMITMSFLSILIGGWGGL 170
Cdd:PRK08668 213 FPLHVWAPDAYSEAPqsfsavLSGQLSklgaygfllvlyVLPGTKLFSEFGTYRGVPLFN-YILAWLGNISIIVGTLMAI 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 171 NQTQLRKIMAYSSIAHMGWMTtILLYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLLLSQTWN---------TVPIMT 241
Cdd:PRK08668 292 LQEDIKKLIAYSSVANGGYIL-VGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTGTTKisemgglieKMPFTF 370

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 170026943 242 TFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTY 298
Cdd:PRK08668 371 AMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
96-190 3.02e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.30  E-value: 3.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  96 ILMTMALAIKLGLSPFHFWVPE--VTQGIPLST-------------------GLILLTWQKLAPisilyqispsinlhLM 154
Cdd:PRK06473 209 APILVGFGIKIPLVPFHTWLPDahVEASTPVSVllagvllklgtygllrfgvGLFPEAWVYLAP--------------WL 274

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 170026943 155 ITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK06473 275 ATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK12646 PRK12646
DUF4040 family protein;
92-276 6.35e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 38.58  E-value: 6.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  92 PTASILMTMALAIKLGLSPFHFWVPEVTQG-IPLSTGLILLTWQKlAPISILYQISPSINL-----HLMITMSFLSILIG 165
Cdd:PRK12646 210 IPMIFMFLLGAFTKSAQFPFHIWLPRAMAApTPVSAYLHSATMVK-AGIFLLFRFTPLLGLsnmyiYIVTFVGLITMLFG 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 166 GWGGLNQTQLRKIMAYSSIAHMGWMTTIL----LYNPTLTLLNLLIYIVMTFTMFMLLIQNSTTTTLL------------ 229
Cdd:PRK12646 289 SITALKQWDLKGILAYSTISQLGMIMAMVgiggGYAQHQQDAIASIYVFVLFAALFHLMNHAIFKCALfmgvgiidheag 368

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 170026943 230 ------LSQTWNTVPIMTTFTMLTLLSMGGLPPLTGFMPKWMIIQELTKNKTL 276
Cdd:PRK12646 369 trdiriLSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQL 421
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 110-263 7.99e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 37.98  E-value: 7.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 110 PFHFWVPEVTQG-IPLSTGLILLTWQKlAPISILYQISPSI--NLHLMITMSF---LSILIGGWGGLNQTQLRKIMAYSS 183
Cdd:PRK12647 213 PFHFWLPNAMEApTPVSAYLHSATMVK-AGIYLLARLNPVLggTPLWQTILPLfggLTMLTGALLAVRQTDLKLILAYST 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 184 IAHMGWMTTILLYNPTLTLLNLLIYIVM----TFTMFM----LLIQNSTTTTLLLSQTWNTVPIMTTFTMLTLLSMGGLP 255
Cdd:PRK12647 292 VSALGTLVMLLGLGSELAIKAAVLFLVAhslyKGALFMvagiIDHETGTRDITKLGGLRRAMPITAAAALLAALSMAGLP 371


                 ....*...
gi 170026943 256 PLTGFMPK 263
Cdd:PRK12647 372 PLFGFLAK 379
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 96-317 9.34e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.16  E-value: 9.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  96 ILMTMALAIKLGLSPFHFWVPEVTQGIPLSTGLILLTWQKLAPISILYQISPSINLHLMITMSFLSILIGgwggLNQTQL 175
Cdd:MTH00091  61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQM----FLLKSY 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943 176 RKIMAYSSIAHMGWMttiLLYNPTLTLLNLLIYIVMTFTMFMLLiqnsttttlllsQTWNTVPIMTTFTMLTLLSMGGLP 255
Cdd:MTH00091 137 KNLLILSSTESFNWL---ILSFFFSFFNVFFLFFYYFLLMLFLI------------PKFNNVNKLNFVSWETLLVFMNLP 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 170026943 256 PLTGFMPKWMIIQELTKNKTLILPTLMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQF 317
Cdd:MTH00091 202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 52-188 9.80e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 37.82  E-value: 9.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 170026943  52 ATEASAKYFLTQTTASSLLMLAI--------IINLMHSSQWTIMklFDPTASI----LMTMALAIKLGLSPFHFWVPEVT 119
Cdd:PRK08377 156 AAEASMKYIVLGGIGSSFFLIGValiygatgTLNMAHIAQLAGT--IDPTVAQvglaLLIFGLAVEAELFPLNAWAPDAY 233

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 170026943 120 QGIP------LSTGLILLTWQKLAPISILYQISPSIN--LHLMITMSFLSILIGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:PRK08377 234 QAAPhpitvmFSAFVVKAGLYAMARILYLMQNANGWSsvLKLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVG 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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