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Conserved domains on  [gi|169787763|gb|ACA80283|]
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NADH dehydrogenase subunt 2 (mitochondrion) [Psittacus erithacus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-138

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.50  E-value: 2.06e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787763 321 TNTLIPMLTSLSTLLLPLSPMIPTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-138

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.50  E-value: 2.06e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787763 321 TNTLIPMLTSLSTLLLPLSPMIPTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 2.30e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   23 SNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQL--THPP------ 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   94 ---SCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLSPT---LLTAMAIMSIGL 164
Cdd:pfam00361  81 lllLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  165 GGWMGLNQTQIRKIMAFSSISHLGWMTTII----IYNPKLTLLTFYIYSLMTTSIFL-----TLDTAKTLKLTTLMTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 169787763  236 KIPMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-281 6.90e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 75.15  E-value: 6.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  14 LLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLF-SSMTNAwATGQWDITQL-- 89
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  90 ------THPP----SCLLLTTAIAIKLGLTPFHFWFPEVLQGSslttalllstlmklpPTTI------------------ 141
Cdd:COG1007  191 alaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallr 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 142 -LLLTSHSLSP---TLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTL--LTFY--IYSLMTT 213
Cdd:COG1007  256 lLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 214 SIFLTLDTAK----------------------TLKLTTLMTSWTKIPmltttlmlallslaglpPLTGFLPKWLIIQELT 271
Cdd:COG1007  336 GAFAVILLLSrkggeaeeiedlaglarrspllALAMTIFLLSLAGIP-----------------PTAGFFGKFYVFSAAV 398

                        330
                 ....*....|
gi 169787763 272 KQEMIVTATI 281
Cdd:COG1007  399 EAGLYWLAVI 408
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-282 2.73e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.36  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   14 LLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   93 PSC------------LLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKL----PPTTILLLTSHSLSPT---L 153
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIaifaVFLRLFLYILFGFSEAwqiF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  154 LTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTL--LTFY--IYSLMTTSIFLTLDTAKTLKLT- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 169787763  229 ----TLMTSWTKI-PMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATII 282
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIA 410
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-138

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 396.50  E-value: 2.06e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 169787763 321 TNTLIPMLTSLSTLLLPLSPMIPTIT 346
Cdd:MTH00112 321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-327 1.10e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 331.12  E-value: 1.10e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 ....*..
gi 169787763 321 TNTLIPM 327
Cdd:MTH00070 321 TNNLLSL 327
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 2.27e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 327.92  E-value: 2.27e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTtILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAPTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                 ....
gi 169787763 321 TNTL 324
Cdd:MTH00135 320 QLTL 323
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-326 5.72e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 290.98  E-value: 5.72e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSN-KMKQWSTKN 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNmKMKWQFENT 320


                 ....*..
gi 169787763 320 PTNTLIP 326
Cdd:MTH00105 321 KPMTLLP 327
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-327 2.77e-84

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 258.75  E-value: 2.77e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNP 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                 ....*..
gi 169787763 321 TNTLIPM 327
Cdd:MTH00200 321 SNLLVGL 327
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 11-345 2.29e-70

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 223.27  E-value: 2.29e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  11 TSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLT 90
Cdd:MTH00041  11 TSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  91 HPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIMSIGLGGWMGL 170
Cdd:MTH00041  91 NTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 171 NQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPMLTTTLMLALLS 250
Cdd:MTH00041 171 NQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILS 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 251 LAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVTLPPNSSNKMKQWSTKNPTNTLIPMLTS 330
Cdd:MTH00041 251 LGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGVILSI 330

                        330
                 ....*....|....*
gi 169787763 331 LSTLLLPLSPMIPTI 345
Cdd:MTH00041 331 LSSISILGLLLIPLF 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 4.19e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 162.30  E-value: 4.19e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWa 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 tgqwdITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPttiLLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATIISLLSLLGLFFYLRLAYCSTVtlppNSSNKMKqWSTKNP 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLM----LNYNKNK-WNLKKK 307

                        330       340
                 ....*....|....*....|....*
gi 169787763 321 TNTLIPMLTSLSTLLLPLSPMIPTI 345
Cdd:MTH00160 308 KNKFSLILNFLSFISLFGLILSSLL 332
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-277 1.15e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 145.41  E-value: 1.15e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTSLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWA 80
Cdd:MTH00144   1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITqlthppscLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPT-TILLLTSHSLSPTLLTAMAI 159
Cdd:MTH00144  81 SFSWFSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLfLLSNFLDLYWLAYLLCVISV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 160 MSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTaKTLKLTTLMTSWTKIPM 239
Cdd:MTH00144 153 LSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYK 231

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 169787763 240 LTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIV 277
Cdd:MTH00144 232 TGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLL 269
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-277 6.48e-38

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 137.99  E-value: 6.48e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   1 MSPLAKLISTTsLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSmtnawa 80
Cdd:MTH00011   4 TFPTMFLFSST-MTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  81 TGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIM 160
Cdd:MTH00011  77 TMMWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAM 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 161 SIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPML 240
Cdd:MTH00011 157 SALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTT 236

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIV 277
Cdd:MTH00011 237 SMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMIL 273
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-270 1.68e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 125.94  E-value: 1.68e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  12 SLLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATgqwditqLTH 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL-------YLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  92 PPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPttILLLTSHSLSPTLLTAMAIMSIGLGGWMGLN 171
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 172 QTQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYSLMTTSIFLTLDTAKTLKLTTLMTSWTKIPMLTTTLMLALLSL 251
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250
                 ....*....|....*....
gi 169787763 252 AGLPPLTGFLPKWLIIQEL 270
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSL 255
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 2.30e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.30e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   23 SNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQL--THPP------ 93
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   94 ---SCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLM-KLPPTTILLLTS--HSLSPT---LLTAMAIMSIGL 164
Cdd:pfam00361  81 lllLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLIRRSLlyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  165 GGWMGLNQTQIRKIMAFSSISHLGWMTTII----IYNPKLTLLTFYIYSLMTTSIFL-----TLDTAKTLKLTTLMTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 169787763  236 KIPMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-281 1.52e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 82.39  E-value: 1.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  13 LLLGTTITITSNHWAMAWTGLEINTLAIIPLI-SKSHHPRAIEATTKYFLVQAAASTLVLFS-------------SMTNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  79 WATGQWDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLltSHSLSPTLLTAMA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILV--SIGLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 159 IMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTII----IYNPKLTLLTFYIYSLMTTSIF---LTLDTAKTLkLTTLM 231
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFsiiLALNVYKNL-IIEFS 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 169787763 232 TSWTKIPMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATI 281
Cdd:MTH00196 239 GLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLL 288
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-281 6.90e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 75.15  E-value: 6.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  14 LLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLF-SSMTNAwATGQWDITQL-- 89
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIaa 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  90 ------THPP----SCLLLTTAIAIKLGLTPFHFWFPEVLQGSslttalllstlmklpPTTI------------------ 141
Cdd:COG1007  191 alaaggANSPllllGLVLVLAGLAFKLSAVPFHMWTPDVYEGA---------------PTPVtaflatapkiaafaallr 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 142 -LLLTSHSLSP---TLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTL--LTFY--IYSLMTT 213
Cdd:COG1007  256 lLVEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYllAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 214 SIFLTLDTAK----------------------TLKLTTLMTSWTKIPmltttlmlallslaglpPLTGFLPKWLIIQELT 271
Cdd:COG1007  336 GAFAVILLLSrkggeaeeiedlaglarrspllALAMTIFLLSLAGIP-----------------PTAGFFGKFYVFSAAV 398

                        330
                 ....*....|
gi 169787763 272 KQEMIVTATI 281
Cdd:COG1007  399 EAGLYWLAVI 408
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-281 1.89e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 74.09  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  14 LLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQL--- 89
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIaka 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  90 -----THPP----SCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKL----PPTTILLLTSHSLSPT---L 153
Cdd:PRK05777 193 ladgsGNSLlllfGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 154 LTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTL--LTFY--IYSLMTTSIF--LTLDTAKTLKL 227
Cdd:PRK05777 273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYllAYLFMTLGAFgvISLLRRKGGEA 352

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 169787763 228 TTLmTSWTKI----PMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATI 281
Cdd:PRK05777 353 ESI-SDFAGLskrsPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVI 409
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-282 2.73e-13

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 70.36  E-value: 2.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   14 LLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   93 PSC------------LLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKL----PPTTILLLTSHSLSPT---L 153
Cdd:TIGR01770 192 LSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIaifaVFLRLFLYILFGFSEAwqiF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  154 LTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTIIIYNPKLTL--LTFY--IYSLMTTSIFLTLDTAKTLKLT- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkaVLFYifIYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 169787763  229 ----TLMTSWTKI-PMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATII 282
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIA 410
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-282 6.86e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 69.02  E-value: 6.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  13 LLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLTH- 91
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAr 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  92 ----PPS-----CLLLTTAIAIKLGLTPFHFWFPEVlqgsslttalllstlMKLPPT--------------------TIL 142
Cdd:COG0651  196 laelDPGlllaaFALLLVGFGIKAALFPLHFWLPDA---------------YPAAPSpvsallsglltkvgvyailrVLT 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 143 LLTSHSLSP---TLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTT-IIIYNPK-LTLLTFYI--YSLMTTSI 215
Cdd:COG0651  261 LLFGADPALflgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLgLGLGTPLgLAGALFHLlnHALAKALL 340

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169787763 216 FLT----LDTAKTLKLTTLMTSWTKIPMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATII 282
Cdd:COG0651  341 FLAagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVL 411
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 7.62e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 68.89  E-value: 7.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  13 LLLGTTITITSNHWAMAWTGLEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDI----T 87
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  88 QLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTShsLSPTLLTAMAIMSIGLGGW 167
Cdd:MTH00199 186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIG--PVTNVVLICAVLSIIYGAI 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 168 MGLNQTQIRKIMAFSSISHLGWMTTIIIYNP----KLTLLTFYIYSLMTT---SIFLTLDTAKTLkLTTLMTSWTKIPML 240
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSIcsfSIILSLKLTKGL-IVEVSGLSRKNPVI 342

                        250       260
                 ....*....|....*....|....*..
gi 169787763 241 TTTLMLALLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199 343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-190 5.82e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.81  E-value: 5.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  15 LGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAI---------EATTKYFLVQAAASTLVLFSSMTNAWATGQ-- 83
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  84 ------------WDITQLTHPPSCLLLTTAIAIKLGLTPFHFWFPEVLQGSSLTTALLLSTLMKLppTTILLLTSHSLSP 151
Cdd:MTH00198 279 mlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 169787763 152 TLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWM 190
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFI 395
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-191 2.74e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 55.09  E-value: 2.74e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  38 LAIIP---LISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQW--DITQLTH---PPS-----CLLLTTAIAI 104
Cdd:COG1008  142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplPLTaqlllFLAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 105 KLGLTPFHFWFPEVLQGSSlttalllstlmklPPTTILL---------------------LTSHSLSPTLLtAMAIMSIG 163
Cdd:COG1008  222 KVPMFPFHTWLPDAHVEAP-------------TAGSVLLagvllkmggygllrfalplfpEASAYFAPLLA-ALGVIGII 287

                        170       180
                 ....*....|....*....|....*...
gi 169787763 164 LGGWMGLNQTQIRKIMAFSSISHLGWMT 191
Cdd:COG1008  288 YGALVALAQTDLKRLIAYSSVSHMGFVL 315
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-263 2.05e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 52.31  E-value: 2.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  51 RAIEATTKYFLVQAAASTLVLFS-SMTNAWATGQWDI---------TQLTHPPSCLL----LTTAIAIKLGLTPFHFWFP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELqeivnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 117 EVLQGSSLTTALLLSTLMK---LPPTTILLLTSHSLSPT----LLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKvaaSALATRIFDIPFYFSSNewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 190 MTTIII-------YNPKLTLLTFYIyslmttsiFLTLDTAKTLKLTTLMT----------SWTKIPMLTTTLMLALLSLA 252
Cdd:CHL00049 319 VIIGIIvgdsndgYASMITYMLFYI--------FMNLGTFACIVLFGLRTgtdnirdyagLYTKDPFLALSLALCLLSLG 390

                        250
                 ....*....|.
gi 169787763 253 GLPPLTGFLPK 263
Cdd:CHL00049 391 GIPPLAGFFGK 401
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-194 1.24e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 49.75  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  13 LLLGTTITITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLVQAAA------STLVLFSSMTNAWATGQWDI 86
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  87 TQLTH-----PPSCLLLT-----TAIAIKLGLTPFHFWFPEV-LQGSSLTTALLLSTLMKLPPTTILLLTS-------HS 148
Cdd:PRK08676 191 TELAAhasllSPSVLGASflfifIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRLSAllrqsgaAE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 169787763 149 LSPTLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTTII 194
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 2.41e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.17  E-value: 2.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763   50 PRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQ-WDITQLTHPPSCLLLTT--------AIAIKLGLTPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGVQTwlflaffiAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 169787763  120 QGSSLTTALLLSTLMKLPPTTILLL-------TSHSLSPtLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMT 191
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFnlplfpdASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-190 6.62e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 44.70  E-value: 6.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  33 LEINTLAIIPLIS-KSHHPRAIEATTKYFLVQAAASTLVLFSSmtnAWATGQWDI-------TQLTHPPSCL------LL 98
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTlnmaylaVKMSENPTVVakialaLF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  99 TTAIAIKLGLTPFHFW----FPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPT----LLTAMAIMSIGLGGWMGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWlpdaYPAAPSSISAMLLVIKQAGLYALARVLFSIYGPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180
                 ....*....|....*....|
gi 169787763 171 NQTQIRKIMAFSSISHLGWM 190
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYM 326
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-191 6.66e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.42  E-value: 6.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  38 LAIIP---LISKSHHPRAIEATTKYFLVQAAASTLVLFSSMT----NAWATGQWDITQLTHPPSCLLLTT--------AI 102
Cdd:PRK05846 142 AMLIPmyfLIGVWGGKNRIYAATKFFLYTLLGSLLMLVAIIYlvvvYYNATGTFDIADLLNLPLPPGVQYwlflaffiAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 103 AIKLGLTPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPpttILLLTSHSLSPtLLTAMAIMSIGLGGWMGLN 171
Cdd:PRK05846 222 AVKMPMFPLHTWLPDahvqaptagsvLLAGILLKMGAYGLLRFSLP---LFPDASHEFAP-IIITLGVIAIIYGALVALA 297

                        170       180
                 ....*....|....*....|
gi 169787763 172 QTQIRKIMAFSSISHLGWMT 191
Cdd:PRK05846 298 QTDIKKLIAYSSISHMGFVT 317
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-192 1.04e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 43.77  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  20 TITSNHWAMAWTGLEINTLAIIPLISKSHHPRAIEATTKYFLV------QAAASTLVLFSSMTNAWATGQWDI--TQLTH 91
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIIcsvgvaFALFGTILVYANAATVMGDGEMAIlwTELLK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  92 PPSCL---LLTTAIAI-------KLGLTPFHFWFPE-----------VLQGSSLTTALLLSTLMKLppttILLLTSHSLS 150
Cdd:PRK06458 204 HASLLdptLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYI----LIDAAIGSDF 279

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 169787763 151 P-TLLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMTT 192
Cdd:PRK06458 280 PgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-282 1.73e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.45  E-value: 1.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  34 EINTLA---IIPLISKshhpRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDIT-------QLTHPPSC----LLLT 99
Cdd:PRK08668 128 EIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFAdisqgliNDTSTGFAlivfLFLL 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 100 TAIAIKLGLTPFHFWFPE-----------VLQGSSLTT-ALLLSTLMKLPPTTILLLT-----SHSLSPTLLTAMAIMSI 162
Cdd:PRK08668 204 AFGVAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLgAYGFLLVLYVLPGTKLFSEfgtyrGVPLFNYILAWLGNISI 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 163 GLGGWMGLNQTQIRKIMAFSSISHLGWmttIIIYNPKLTLL-----TFYIYS--LMTTSIFLTLDT----AKTLKLTTLM 231
Cdd:PRK08668 284 IVGTLMAILQEDIKKLIAYSSVANGGY---ILVGLGLGTSLgfaggLFHVFNhaLFKGLFFLIFAAviyrTGTTKISEMG 360

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 169787763 232 TSWTKIPMLTTTLMLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATII 282
Cdd:PRK08668 361 GLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMA 411
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-191 2.44e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 42.83  E-value: 2.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  78 AWATGQWDITQLTHPPSCLL---LTTAIAI--------KLGLTPFHFWFPEVLQGsslttalllstlmklpPTTI----- 141
Cdd:COG1009  186 GAIAGTLNFSELLAAAPTILsspLLTLILLllllgafgKSAQFPLHFWLPDAMEG----------------PTPVsallh 249

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 169787763 142 ----------LLLTSH---SLSPTLLTAMAImsIGL-----GGWMGLNQTQIRKIMAFSSISHLGWMT 191
Cdd:COG1009  250 aatmvkagvyLLARLSplfALSPVWLTVVAI--IGAitalfAALIALAQTDIKRVLAYSTVSQLGYMF 315
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-263 9.02e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 40.97  E-value: 9.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  48 HHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLTHPPSC--------LLLTTAIAIKLGLT------PFHF 113
Cdd:PRK12649 156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELienikghpLFLITLILIFIGAAaksaqgPFYI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 114 WFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPT-----LLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLG 188
Cdd:PRK12649 236 WLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLA 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 189 WMTTIIIYN----PKLTLL--TFYIYSLMTTSIFLTL------DTAKTLKLTTLMTSWTKIPMLTTTLMLALLSLAGLPP 256
Cdd:PRK12649 316 YLMTMYGYTtyhePGLGVAaaTFHLLNHATFKACLFLvagivaHEAATRDIRKLGGLRKEMPITFIVASIAALAMAGIPP 395


                 ....*..
gi 169787763 257 LTGFLPK 263
Cdd:PRK12649 396 LNGFLSK 402
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-282 1.23e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 40.63  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  33 LEINTLAIIPLISKSHHPRAIEATTKYFLVQAAASTLVLFS-SMTNAwATGQWDITQLTH--PPSCLLLT------TAIA 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAGalAENPTVVTafgfvlLALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 104 IKLGLTPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSpTLLTAMAIMSIGLGGWMGLNQ 172
Cdd:PRK08375 214 LKAAVFPLHTWLPRaypaappvvtaLLSGLVTKVAVYALIRIYFTVFGGDFRFALGLG-WLLAVLALLSMLVGSLAALGQ 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 173 TQIRKIMAFSSISHLGWMTTIIIYNPKLTLL--TFYI--YSLMTTSIFLTL----DTAKTLKLTTLMTSWTKIPMLTTTL 244
Cdd:PRK08375 293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAagLLHLlhHALMKGALFLAAgaieVTYGTRRLSELSGLGRRMPLTAAAF 372

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 169787763 245 MLALLSLAGLPPLTGFLPKWLIIQELTKQEMIVTATII 282
Cdd:PRK08375 373 AVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVL 410
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-263 1.31e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 40.42  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  50 PRAIEATTKYFLVQAAASTLVLF-SSMTNAWATGQWDIT----QLTHPPSCLLLTT------AIAIKLGLTPFHFWFPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSaialALITSPSLGLALAlvfviaGIAFKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 119 LQGSSLTTALLLSTLMKLPPTTI---LLLTSHSLSPT----LLTAMAIMSIGLGGWMGLNQTQIRKIMAFSSISHLGWMT 191
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 192 TIIIYNPK--LTLLTFY--IYSLM-----TTSIFLTLDTAkTLKLTTLMTSWTKIPMLTTTLMLALLSLAGLPPLTGFLP 262
Cdd:PRK02504 317 IGLVAGTEagYASMVFYllAYLFMnlgafACVILFSLRTG-TDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFG 395


                 .
gi 169787763 263 K 263
Cdd:PRK02504 396 K 396
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 101-219 1.40e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.29  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 101 AIAIKLGLTPFHFWFPE-----------VLQGSSLTTALLLSTLMKLPpttILLLTSHSLSPTLLtAMAIMSIGLGGWMG 169
Cdd:MTH00226 239 AMAVKIPIFPFHIWLPKahveapvagsvLLAGILLKLGGYGLVRLSWP---ILPLGAQNLAPAVI-AMGIVGIVYGSFAT 314

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 169787763 170 LNQTQIRKIMAFSSISHLGWMTtiiiynpkLTLLTFYIYSLmTTSIFLTL 219
Cdd:MTH00226 315 CRQIDVKRLVAYSSVAHMGLVS--------ITLVTHDIIGL-TGSIFIML 355
PRK12650 PRK12650
DUF4040 family protein;
29-263 4.88e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 4.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  29 AWtglEINTLAIIPLISKSHhPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDITQLTHPPSCL---LLTTAIAIK 105
Cdd:PRK12650 138 AW---ELVSLASFFLIARSG-SGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSLSGILHSDVWAekpGLTTVVAVL 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 106 LGLT--------PFHFWFPEVLQGSSLTTALLLSTLMKLPPTTILLLTSHSLSPTLLTAMAIMSIGL-----GGWMGLNQ 172
Cdd:PRK12650 214 IAVAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVAVWNWLLIIVGMitalmGAVFAVQK 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763 173 TQIRKIMAFSSISHLGWMTTIIIYNPKLTLLTFYIYS----LMTTSIFLTLDT----AKTLKLTTLMTSWTKIPMLTTTL 244
Cdd:PRK12650 294 TDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTlahaLFKSSLFMLIGVvdhqAGTRDIRRLGSLWRRMPFTFVSV 373

                        250
                 ....*....|....*....
gi 169787763 245 MLALLSLAGLPPLTGFLPK 263
Cdd:PRK12650 374 TIAALSMAAVPPLFGFVSK 392
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
13-120 7.84e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 38.14  E-value: 7.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169787763  13 LLLGTTITITSNHWAM---AW--TGLEINTLaiipLISKSHHPRAIEATTKYFLVQAAASTLVLFSSMTNAWATGQWDIT 87
Cdd:PRK08168 109 VLAAVHLLVLSDHLLVliaAWaaISLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLS 184

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 169787763  88 QL--------THPP---SCLLLTTAIAIKLGLTPFHFWFPEVLQ 120
Cdd:PRK08168 185 ALwahlaaqgASPSlqaAALLLVLAVILKTAQLPVHGWLIQVME 228
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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