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Conserved domains on  [gi|1696206677|ref|XP_029631414|]
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zinc finger protein OZF-like [Salmo trutta]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 12142358)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
176-438 4.10e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 4.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 176 SYLGALNIHLRTHTGEKPYSCDQCGKSFSQSGTLNSHQRTHTGEKPYSCDRCGKRFAQSRELNRHQRTHTGEKPYSCDQC 255
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 256 GKSFALSKALTIHQRIHTGV-------KPYSCGQCGKSFNQSGNLTTHKLT--HTG--VKPYSCD--QCGMSFARASTLN 322
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALK 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 323 RHQLTHTGEKPYSC--DQCGKSF-----ALSDKRTIHQRTHTGEKPYCC--YQCGKSFAVASTLIRHYRKHTGEKPYSCD 393
Cdd:COG5048   341 RHILLHTSISPAKEklLNSSSKFspllnNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCK 420

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1696206677 394 --QCGKSFAVASTLNTHQRTHTGEKPYCCDQCgKSFAVASNLIRHHR 438
Cdd:COG5048   421 npPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
153-177 7.42e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.42e-03
                          10        20
                  ....*....|....*....|....*
gi 1696206677 153 FKSHLRIHKGERPYPCLDCGKRFSY 177
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
176-438 4.10e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 4.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 176 SYLGALNIHLRTHTGEKPYSCDQCGKSFSQSGTLNSHQRTHTGEKPYSCDRCGKRFAQSRELNRHQRTHTGEKPYSCDQC 255
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 256 GKSFALSKALTIHQRIHTGV-------KPYSCGQCGKSFNQSGNLTTHKLT--HTG--VKPYSCD--QCGMSFARASTLN 322
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALK 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 323 RHQLTHTGEKPYSC--DQCGKSF-----ALSDKRTIHQRTHTGEKPYCC--YQCGKSFAVASTLIRHYRKHTGEKPYSCD 393
Cdd:COG5048   341 RHILLHTSISPAKEklLNSSSKFspllnNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCK 420

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1696206677 394 --QCGKSFAVASTLNTHQRTHTGEKPYCCDQCgKSFAVASNLIRHHR 438
Cdd:COG5048   421 npPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
236-260 1.02e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.02e-04
                          10        20
                  ....*....|....*....|....*
gi 1696206677 236 ELNRHQRTHTGEKPYSCDQCGKSFA 260
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
153-177 7.42e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.42e-03
                          10        20
                  ....*....|....*....|....*
gi 1696206677 153 FKSHLRIHKGERPYPCLDCGKRFSY 177
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
176-438 4.10e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 4.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 176 SYLGALNIHLRTHTGEKPYSCDQCGKSFSQSGTLNSHQRTHTGEKPYSCDRCGKRFAQSRELNRHQRTHTGEKPYSCDQC 255
Cdd:COG5048   181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 256 GKSFALSKALTIHQRIHTGV-------KPYSCGQCGKSFNQSGNLTTHKLT--HTG--VKPYSCD--QCGMSFARASTLN 322
Cdd:COG5048   261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCPysLCGKLFSRNDALK 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 323 RHQLTHTGEKPYSC--DQCGKSF-----ALSDKRTIHQRTHTGEKPYCC--YQCGKSFAVASTLIRHYRKHTGEKPYSCD 393
Cdd:COG5048   341 RHILLHTSISPAKEklLNSSSKFspllnNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCK 420

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1696206677 394 --QCGKSFAVASTLNTHQRTHTGEKPYCCDQCgKSFAVASNLIRHHR 438
Cdd:COG5048   421 npPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-441 2.04e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 2.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 164 RPYPCLDCGKRFSYLGALNIHLRTHTGEKPYSCDQCGKSFSQSGTLNS--HQRTHTGEKPY-SCDRCGKRFAQSRELNRH 240
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELsrHLRTHHNNPSDlNSKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 241 QRTHTGEKPYSCDQCGKSFALSKALTIHQRIHTGVKPYSCGQCGKSFNQS----------------------GNLTTHKL 298
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 299 THTGVKPYSCDQCGMSFARASTLNRHQLTHTGEKPYSCDQCGKSFALSDKRTIHQRT-HTGEKPYCCYQCGKSF-AVAST 376
Cdd:COG5048   192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLsSSDSSSSASESPRSSLpTASSQ 271

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1696206677 377 LIRHYRKHTGE-----KPYSCDQCGKSFAVASTLNTHQRT--HTGE--KPYCCD--QCGKSFAVASNLIRHHRTHT 441
Cdd:COG5048   272 SSSPNESDSSSekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHT 347
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
155-408 3.02e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.39  E-value: 3.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 155 SHLRIHKGERPYPCLDCGKRFSYLGALNIHLRTHTGEKPYSCDQCGKSFSQS------GTLNSHQRTHTGEKPYSCDRCG 228
Cdd:COG5048   188 ISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSllsqspSSLSSSDSSSSASESPRSSLPT 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 229 KRFAQSRELNRHQRTHTG-EKPYSCDQCGKSFALSKALTIHQR--IHTG--VKPYSCG--QCGKSFNQSGNLTTHKLTHT 301
Cdd:COG5048   268 ASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGesLKPFSCPysLCGKLFSRNDALKRHILLHT 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 302 GVKPYSC--DQCGMSFARASTLNRHQLTH-----TGEKPYSCD--QCGKSFALSDKRTIHQRTHTGEKPYCCY--QCGKS 370
Cdd:COG5048   348 SISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKS 427

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1696206677 371 FAVASTLIRHYRKHTGEKPYSCDQCgKSFAVASTLNTH 408
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSIL-KSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
134-432 4.36e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.84  E-value: 4.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 134 AEKPYCCSQCGKCFAASNTFKSHLRIHKGERPYPCLD--CGKRFSYLGALNIHLRTHTGEKPYSCDQCGKS--FSQSGTL 209
Cdd:COG5048    30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLsnSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 210 NSHQRTHTgEKPYSCDRCGKRFAQSRELNRHQRTHTGEKPYSCDQCGKSFALSK----------------------ALTI 267
Cdd:COG5048   110 LSSSSSNS-NDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpplpanslskdpssnlSLLI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 268 HQRIHTGVKPYSCGQCGKSFNQSGNLTTHKLTHTGVKPYSCDQCGMSFARASTLNRHQLTHTGEKPYSCDQCGKSFALSD 347
Cdd:COG5048   189 SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTA 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 348 KRTIHQRTHTGE-------KPYCCYQCGKSFAVASTLIRHYRK--HTGE--KPYSCD--QCGKSFAVASTLNTHQRTHTG 414
Cdd:COG5048   269 SSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTS 348

                         330       340
                  ....*....|....*....|
gi 1696206677 415 EKPYCC--DQCGKSFAVASN 432
Cdd:COG5048   349 ISPAKEklLNSSSKFSPLLN 368
zf-H2C2_2 pfam13465
Zinc-finger double domain;
236-260 1.02e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.02e-04
                          10        20
                  ....*....|....*....|....*
gi 1696206677 236 ELNRHQRTHTGEKPYSCDQCGKSFA 260
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
204-290 1.18e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 204 SQSGTLNSHQRTHTGE----KPYSCDRCGKRFAQSRELNRHQRTHTGEKPYSC--DQCGKSFALSKALTIHQRIHTGVKP 277
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPS 91

                          90
                  ....*....|...
gi 1696206677 278 YSCGQCGKSFNQS 290
Cdd:COG5048    92 DLNSKSLPLSNSK 104
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
165-325 1.20e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.30  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 165 PYPCLDCGKRFSYLGALNIHLRT--HTGE--KPYSCD--QCGKSFSQSGTLNSHQRTHTGEKPYSC--DRCGKRFAQ--- 233
Cdd:COG5048   289 PIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPlln 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1696206677 234 --SRELNRHQRTHTGEKPYSCD--QCGKSFALSKALTIHQRIHTGVKPYSC--GQCGKSFNQSGNLTTHKLTHTGVKPYS 307
Cdd:COG5048   369 nePPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                         170
                  ....*....|....*...
gi 1696206677 308 CDQCGMSFARASTLNRHQ 325
Cdd:COG5048   449 CSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
180-205 3.75e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 3.75e-04
                          10        20
                  ....*....|....*....|....*.
gi 1696206677 180 ALNIHLRTHTGEKPYSCDQCGKSFSQ 205
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
377-400 6.69e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.69e-04
                          10        20
                  ....*....|....*....|....
gi 1696206677 377 LIRHYRKHTGEKPYSCDQCGKSFA 400
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
321-344 7.60e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 7.60e-04
                          10        20
                  ....*....|....*....|....
gi 1696206677 321 LNRHQLTHTGEKPYSCDQCGKSFA 344
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
405-428 7.68e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 7.68e-04
                          10        20
                  ....*....|....*....|....
gi 1696206677 405 LNTHQRTHTGEKPYCCDQCGKSFA 428
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
209-233 1.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.04e-03
                          10        20
                  ....*....|....*....|....*
gi 1696206677 209 LNSHQRTHTGEKPYSCDRCGKRFAQ 233
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
352-372 4.72e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.72e-03
                          10        20
                  ....*....|....*....|.
gi 1696206677 352 HQRTHTGEKPYCCYQCGKSFA 372
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
292-317 5.69e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 5.69e-03
                          10        20
                  ....*....|....*....|....*.
gi 1696206677 292 NLTTHKLTHTGVKPYSCDQCGMSFAR 317
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
153-177 7.42e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.42e-03
                          10        20
                  ....*....|....*....|....*
gi 1696206677 153 FKSHLRIHKGERPYPCLDCGKRFSY 177
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
264-289 8.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 8.03e-03
                          10        20
                  ....*....|....*....|....*.
gi 1696206677 264 ALTIHQRIHTGVKPYSCGQCGKSFNQ 289
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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