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Conserved domains on  [gi|1677537212|emb|VTN28719|]
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putative glucosamine-6-phosphate deaminase [Klebsiella pneumoniae]

Protein Classification

glucosamine/galactosamine-6-phosphate isomerase/deaminase family protein( domain architecture ID 10013934)

glucosamine/galactosamine-6-phosphate isomerase/deaminase family protein similar to Escherichia coli protein YieK

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-239 3.83e-158

glucosamine-6-phosphate deaminase;


:

Pssm-ID: 183470  Cd Length: 239  Bit Score: 437.65  E-value: 3.83e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKTFYDRVHYYNFDEIPFRGQSREGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  81 SNLRQLFYTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1677537212 161 NSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ 239
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVILDEAAAAELAL 239
 
Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-239 3.83e-158

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 437.65  E-value: 3.83e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKTFYDRVHYYNFDEIPFRGQSREGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  81 SNLRQLFYTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1677537212 161 NSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ 239
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVILDEAAAAELAL 239
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 10-237 1.45e-75

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 228.14  E-value: 1.45e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  10 EEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDEIPFRGQSREGVTISNLRQLFY 88
Cdd:cd01399     1 EEMSEAAAELIAELIREKPPAVLGLATGSTPLGVYEELIELHKeGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMRENLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  89 TPAQIKEENIHKLT------LDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHD-QTVEVpihgEMIALIAN 161
Cdd:cd01399    81 DHIDIKPENIHIPDgnaadlEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRtRVVTL----DESTRQAN 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1677537212 162 SEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAEL 237
Cdd:cd01399   157 ARFFDGDEDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVILDEAAASEL 232
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-238 2.21e-55

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 177.28  E-value: 2.21e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYIT----APRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDEipfrgqsR 75
Cdd:COG0363     2 MRVIIFPDAEELAAAAAERAAERIAeaiaEKGRAVLGLAGGSTPLGLYEELARLHKeGGLDWSRVHVFNLDE-------Y 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  76 EGVTI----SN---LRQLFYTPAQIKEENIH-----KLTLDNAAQH-DRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRF 142
Cdd:COG0363    75 VGLPPdhpqSNrrfMREALLDHVDIPPENIHipdgeAEDPEAAAARyEALIAEAGGIDLQLLGIGEDGHIAFNFPGSPFL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 143 HDQTVEVPIHGEMIAliANSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLH 222
Cdd:COG0363   155 SETDRVVTLDESTRQ--ANARFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQGH 232

                         250
                  ....*....|....*.
gi 1677537212 223 PSLVIIADKAAAAELQ 238
Cdd:COG0363   233 PNVTWFLDEAAASLLT 248
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
24-217 8.56e-20

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 84.21  E-value: 8.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  24 ITAPRRVNLAVTAGSTPKRMYEHLtAAVKGKTFYDRVHYYNFDE--IPFrGQSRegvtiSN---LRQLFYTPAQIKEENI 98
Cdd:pfam01182  22 LAERGRFTLALSGGSTPKPLYELL-AAAPARLDWSRVHVFWGDErcVPP-DDPD-----SNygmAREALLSHVPIPASNV 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  99 HKLTLDN------AAQHDRQLEEAGG------LDLMVLGLGADGHFCGNLPNTTrfhdqtvEVPIHGEMIALIANSEMGg 166
Cdd:pfam01182  95 HPIPASAadpeeaAAAYEAELRELLPdlelpvFDLVLLGMGPDGHTASLFPGSP-------ALEETDRLVVAVTDSPKP- 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1677537212 167 disavPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSvQVPAS 217
Cdd:pfam01182 167 -----PPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAA 211
 
Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-239 3.83e-158

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 437.65  E-value: 3.83e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKTFYDRVHYYNFDEIPFRGQSREGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  81 SNLRQLFYTPAQIKEENIHKLTLDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1677537212 161 NSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAELQQ 239
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVILDEAAAAELAL 239
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 10-237 1.45e-75

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 228.14  E-value: 1.45e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  10 EEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDEIPFRGQSREGVTISNLRQLFY 88
Cdd:cd01399     1 EEMSEAAAELIAELIREKPPAVLGLATGSTPLGVYEELIELHKeGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMRENLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  89 TPAQIKEENIHKLT------LDNAAQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHD-QTVEVpihgEMIALIAN 161
Cdd:cd01399    81 DHIDIKPENIHIPDgnaadlEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRtRVVTL----DESTRQAN 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1677537212 162 SEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADKAAAAEL 237
Cdd:cd01399   157 ARFFDGDEDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVILDEAAASEL 232
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-238 2.21e-55

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 177.28  E-value: 2.21e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYIT----APRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDEipfrgqsR 75
Cdd:COG0363     2 MRVIIFPDAEELAAAAAERAAERIAeaiaEKGRAVLGLAGGSTPLGLYEELARLHKeGGLDWSRVHVFNLDE-------Y 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  76 EGVTI----SN---LRQLFYTPAQIKEENIH-----KLTLDNAAQH-DRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRF 142
Cdd:COG0363    75 VGLPPdhpqSNrrfMREALLDHVDIPPENIHipdgeAEDPEAAAARyEALIAEAGGIDLQLLGIGEDGHIAFNFPGSPFL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 143 HDQTVEVPIHGEMIAliANSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLH 222
Cdd:COG0363   155 SETDRVVTLDESTRQ--ANARFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQGH 232

                         250
                  ....*....|....*.
gi 1677537212 223 PSLVIIADKAAAAELQ 238
Cdd:COG0363   233 PNVTWFLDEAAASLLT 248
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 1-238 1.08e-42

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 145.36  E-value: 1.08e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYI-----TAPRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDE---IP-- 69
Cdd:PRK00443    1 MRLIILKTAEEVGKWAARHIANRInaflpTKERPFVLGLATGSSPLETYKALIELHKaGKVDFSRVTTFNLDEyvgLPad 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  70 ----FRgqsregvtiSNLRQLFYTPAQIKEENIHKL---TLDNAAQHDR---QLEEAGGLDLMVLGLGADGHFCGNLPNT 139
Cdd:PRK00443   81 hpesYR---------YFMRENFFDHVDIPPENINLLngnAPDPEAECRRyeeKIKSAGGIDLQILGIGENGHIAFNEPGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 140 TrFHDQTVEVPIHGEMIalIANSEM-GGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASV 218
Cdd:PRK00443  152 S-FASRTRIKTLTEDTR--IANSRFfDGDIEQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMWPASI 228

                         250       260
                  ....*....|....*....|
gi 1677537212 219 LKLHPSLVIIADKAAAAELQ 238
Cdd:PRK00443  229 LQLHPKATLVLDEAAASELK 248
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 1-238 9.03e-33

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 119.48  E-value: 9.03e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYI-----TAPRRVNLAVTAGSTPKRMYEHLTAAVK-GKTFYDRVHYYNFDEI----PF 70
Cdd:PTZ00285    1 MRIVISEDADAVADYTSNYIIKRIndfkpTSDRPFVLGLPTGSTPLPTYQELIRAYReGRVSFSNVVTFNMDEYvglpRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  71 RGQSREGVTISNlrqlFYTPAQIKEENIHKL--TLDNAAQHDRQLEEA----GGLDLMVLGLGADGHFCGNLPNTTRfHD 144
Cdd:PTZ00285   81 HPQSYHYFMKEN----FFDHVDIKEENRHILngTAPDLEEECRRYEEKiravGGIDLFLAGIGTDGHIAFNEPGSSL-DS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 145 QTVEVPIHGEMIalIANSEM-GGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHP 223
Cdd:PTZ00285  156 RTRVKSLNQETI--DANARFfGNDISKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGGVTHMCPASALQMHP 233

                         250
                  ....*....|....*
gi 1677537212 224 SLVIIADKAAAAELQ 238
Cdd:PTZ00285  234 AAVLCLDEDATLELK 248
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 4-237 8.43e-28

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 110.89  E-value: 8.43e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   4 IVTEDYEEMSLVASHHVLGYI----TAPRRVNLAVTAGSTPKRMYEHLTAAVK--GKTFYDrVHYYNFDE-IPFRGQSRe 76
Cdd:PRK02122   31 DIFESSEEASRAVAQEIATLIrerqAEGKPCVLGLATGSSPIGVYAELIRMHReeGLSFKN-VITFNLDEyYPMQPDSL- 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  77 GVTISNLRQLFYTPAQIKEENIH-------KLTLDNA-AQHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRfhdQTVE 148
Cdd:PRK02122  109 QSYHRFMKENLFDHVDIPPENIHipdgtipKEEIDEYcRDYEEKIEAAGGIDFQLLGIGRTGHIGFNEPGSGR---NSRT 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 149 VPIHGEMIALIANSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVII 228
Cdd:PRK02122  186 RLVTLDHITRRDAASDFFGEENVPRKAITMGVGTILKARRIVLLAWGEHKAPIIKRAVEGEISDEVPASYLQEHPNATFV 265


                  ....*....
gi 1677537212 229 ADKAAAAEL 237
Cdd:PRK02122  266 LDLAAASEL 274
PRK09762 PRK09762
galactosamine-6-phosphate isomerase; Provisional
 1-231 1.72e-25

galactosamine-6-phosphate isomerase; Provisional


Pssm-ID: 182064  Cd Length: 232  Bit Score: 99.90  E-value: 1.72e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212   1 MKMIVTEDYEEMSLVASHHVLGYITAPRRVNLAVTAGSTPKRMYEHLT-AAVKGKTFYDRVHYYNFDEIPFRGQSREGVT 79
Cdd:PRK09762    1 QTLQQVENYTALSERASEYLLAVIRSKPDAVICLATGATPLLTYHYLVeKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  80 ISNLRQLFYTPAQIKEENIHKLTLDNAAQHD-----RQLEEAGGLDLMVLGLGADGHFCGNLPnttrfhDQTVEVPIH-G 153
Cdd:PRK09762   81 ETFLQQHIVQPLGLREDQLISFRSEEINETEcervtNLIARKGGLDLCVLGLGKNGHLGLNEP------GESLQPACHiS 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1677537212 154 EMIALIANSEMGGDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIADK 231
Cdd:PRK09762  155 QLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGKQDATERFLTAKVSTAIPASFLWLHSNFICLIDR 232
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
24-217 8.56e-20

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 84.21  E-value: 8.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  24 ITAPRRVNLAVTAGSTPKRMYEHLtAAVKGKTFYDRVHYYNFDE--IPFrGQSRegvtiSN---LRQLFYTPAQIKEENI 98
Cdd:pfam01182  22 LAERGRFTLALSGGSTPKPLYELL-AAAPARLDWSRVHVFWGDErcVPP-DDPD-----SNygmAREALLSHVPIPASNV 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  99 HKLTLDN------AAQHDRQLEEAGG------LDLMVLGLGADGHFCGNLPNTTrfhdqtvEVPIHGEMIALIANSEMGg 166
Cdd:pfam01182  95 HPIPASAadpeeaAAAYEAELRELLPdlelpvFDLVLLGMGPDGHTASLFPGSP-------ALEETDRLVVAVTDSPKP- 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1677537212 167 disavPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSvQVPAS 217
Cdd:pfam01182 167 -----PPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAA 211
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 10-229 1.62e-19

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 83.38  E-value: 1.62e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  10 EEMSLVASHHVLG----YITAPRRVNLAVTAGSTPKRMYEHLTAAVKGKtfYDRVHYYNFDE--IPFrGQSRegvtiSN- 82
Cdd:cd01400     1 EALAEALADRIAEalaaAIAKRGRFSLALSGGSTPKPLYELLAAAPALD--WSKVHVFLGDErcVPP-DDPD-----SNy 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212  83 --LRQLFYTPAQIKEENIHK----LTLDNAA-----QHDRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVE--V 149
Cdd:cd01400    73 rlAREALLSHVAIPAANIHPipteLGPEDAAaayekELRALFGGVPPFDLVLLGMGPDGHTASLFPGHPALLEETDRlvV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 150 PIHgemialiansemggDISAVPDSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVIIA 229
Cdd:cd01400   153 AVT--------------DSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPGEVLWF 218
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 120-238 3.21e-05

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 44.08  E-value: 3.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1677537212 120 DLMVLGLGADGHFCGNLPNTTRFHDQTvevpihgEMIALIANSemggdiSAVPDSYVTMGPRSVMAAKNLLLIVSGAAKA 199
Cdd:PLN02360  152 DLILLGMGSDGHVASLFPNHPALEEKD-------DWVTFITDS------PKPPPERITFTLPVINSASNVAVVATGESKA 218

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1677537212 200 HA----LKQVVEGPVSVQVPASVlkLHPS---LVIIADKAAAAELQ 238
Cdd:PLN02360  219 NAvhlaIDDVTEGPDAPSLPARM--VQPTkgkLVWFLDKPAASKLD 262
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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