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Conserved domains on  [gi|166987139|gb|ABZ04521|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Emys orbicularis occidentalis]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-223 2.52e-130

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 374.92  E-value: 2.52e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00124 235 LLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMI 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00124 315 LMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTII 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWGT 223
Cdd:MTH00124 395 LTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-223 2.52e-130

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 374.92  E-value: 2.52e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00124 235 LLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMI 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00124 315 LMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTII 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWGT 223
Cdd:MTH00124 395 LTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-220 1.23e-41

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 147.15  E-value: 1.23e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPL-SKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:COG1008  251 LLKMGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAV 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWS 155
Cdd:COG1008  331 LQMVSHGLITAALFLLVGVLYDRTHTRDIAdlggLAKRM----PVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVN 406

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 166987139 156 NITILMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:COG1008  407 PWLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPL 471
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-166 5.46e-38

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 133.59  E-value: 5.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139    1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:pfam00361 124 LVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIF 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   81 LMIAHGLTSSMLFCLA-NTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:pfam00361 204 HLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFL 283


                  ....*..
gi 166987139  160 LMTGLGT 166
Cdd:pfam00361 284 VLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-186 1.43e-36

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 133.53  E-value: 1.43e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139    1 LLKLGGYGIIRITLTLNP-LSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:TIGR01972 245 LLKMGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAV 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:TIGR01972 325 FQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVA 404

                         170       180
                  ....*....|....*....|....*..
gi 166987139  160 LMTGLGTLITATYTLYMLSTTQWGEMP 186
Cdd:TIGR01972 405 FLAALGIVLAAAYMLTLYKRVFFGELS 431
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-223 2.52e-130

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 374.92  E-value: 2.52e-130
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00124 235 LLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAMI 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00124 315 LMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTII 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWGT 223
Cdd:MTH00124 395 LTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-224 5.43e-119

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 346.13  E-value: 5.43e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00068 235 LLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAII 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00068 315 LMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTIL 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWGTF 224
Cdd:MTH00068 395 ITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-223 2.24e-109

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 321.46  E-value: 2.24e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00110 235 LLKLGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGATA 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00110 315 LMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITII 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWGT 223
Cdd:MTH00110 395 LMGLNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGP 457
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-222 4.11e-95

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 285.31  E-value: 4.11e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00127 236 LLKLGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGALI 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00127 316 LMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTLA 395

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELIWG 222
Cdd:MTH00127 396 LTGLGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-220 3.58e-86

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 262.18  E-value: 3.58e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00206 231 LLKLGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGALL 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00206 311 LMIAHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTLP 390

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00206 391 LLGLGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-220 1.65e-73

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 229.86  E-value: 1.65e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLN-PLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:MTH00044 236 LLKLGGYGLIRLINLFSlPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGAL 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:MTH00044 316 ILMIAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILSF 395

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 166987139 160 LMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00044 396 PIIGLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNII 456
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-220 1.14e-69

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 219.64  E-value: 1.14e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00163 223 LLKLGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSLL 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00163 303 MMIGHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSMI 382

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00163 383 FLMLLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLF 442
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-220 4.83e-63

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 201.61  E-value: 4.83e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00150 194 LLKLGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGALI 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00150 274 MMVSHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFFV 353

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00150 354 PLGLMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLL 413
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-220 5.05e-59

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 192.26  E-value: 5.05e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00014 229 LLKLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGALA 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00014 309 MMIAHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTAI 388

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00014 389 LLAITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLI 448
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-220 8.92e-57

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 186.34  E-value: 8.92e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00205 227 LLKLGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAII 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00205 307 MMVAHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISGI 386

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00205 387 PLSLISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIF 446
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-220 1.23e-41

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 147.15  E-value: 1.23e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPL-SKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:COG1008  251 LLKMGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGAV 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWS 155
Cdd:COG1008  331 LQMVSHGLITAALFLLVGVLYDRTHTRDIAdlggLAKRM----PVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVN 406

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 166987139 156 NITILMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:COG1008  407 PWLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPL 471
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-166 5.46e-38

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 133.59  E-value: 5.46e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139    1 LLKLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:pfam00361 124 LVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIF 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   81 LMIAHGLTSSMLFCLA-NTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:pfam00361 204 HLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFL 283


                  ....*..
gi 166987139  160 LMTGLGT 166
Cdd:pfam00361 284 VLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-186 1.43e-36

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 133.53  E-value: 1.43e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139    1 LLKLGGYGIIRITLTLNP-LSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:TIGR01972 245 LLKMGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAV 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:TIGR01972 325 FQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVA 404

                         170       180
                  ....*....|....*....|....*..
gi 166987139  160 LMTGLGTLITATYTLYMLSTTQWGEMP 186
Cdd:TIGR01972 405 FLAALGIVLAAAYMLTLYKRVFFGELS 431
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-220 2.79e-34

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 127.63  E-value: 2.79e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPL-SKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:PRK05846 253 LLKMGAYGLLRFSLPLFPDaSHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGAI 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMQLLFPLMglwwLLASLTNMALPPTINLMGELTIITSLFNWS 155
Cdd:PRK05846 333 FQMISHGLSSAALFLLVGVLYDRLHTRDIAdyggLAKVMPVLAAFF----LFFAMASLGLPGTSGFVGEFLILLGSFQVN 408

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 166987139 156 NITILMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:PRK05846 409 PVIAFIATTGLILAAVYSLWLYQRVMFGPVKNEVAKLKDLNGRELLILLPLVALLLLLGVYPKPL 473
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-220 2.81e-33

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 124.79  E-value: 2.81e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFMV-LALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:MTH00204 251 LLKLGGYGFLRFSWPLFPAASEYFAPLIVmLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAAV 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:MTH00204 331 FLMLAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGLG 410

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 166987139 160 LMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00204 411 VLVTSGMVWSAAYSLYLYNRISFGGGSNYLLFSRDLNRRELLAILPLIIAIFLLGIVPFII 471
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-189 1.19e-32

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 122.85  E-value: 1.19e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPF-MVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:MTH00217 248 LLKLGGYGFIRFSWPLLPEASEYFSPLiQTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAAI 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:MTH00217 328 FLMLAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIVG 407

                        170       180       190
                 ....*....|....*....|....*....|
gi 166987139 160 LMTGLGTLITATYTLYMLSTTQWGEMPSYI 189
Cdd:MTH00217 408 VLASLGMVLSAGYSIYLYNRVCFGAPSKYL 437
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-220 1.58e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 114.63  E-value: 1.58e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPL-SKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:MTH00226 272 LLKLGGYGLVRLSWPILPLgAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGSI 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:MTH00226 352 FIMLAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPIIG 431

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 166987139 160 LMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHLLMMLHILPTTLLMMKPELI 220
Cdd:MTH00226 432 VFVCSGVILSAVYSFYFANRVTFGAPGNLITFARDVNRREFYITASMVFFAFLIGIYPIFI 492
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-177 1.50e-21

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 92.02  E-value: 1.50e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPfmVLALWGV--IMTGSIC-LRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTG 77
Cdd:PRK12561 227 LLKMGGYALIRFNVQMLPDAHVYFAP--ALAILGVvnIIYGALNaFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISG 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  78 AITLMIAHGLTSSMLFCLANTNYERTHsrTLL------LARNMQLLFPLmglwWLLASLTNMALPPTINLMGELTI---I 148
Cdd:PRK12561 305 AMLQMISHGLIAAALFFLTGVTYERTH--TLSipnmggLAKVMPKTFAL----FTASSMASLALPGMSGFVSELTVflgI 378

                        170       180       190
                 ....*....|....*....|....*....|...
gi 166987139 149 TSLFNWSN----ITILMTGLGTLITATYTLYML 177
Cdd:PRK12561 379 TSSDVYSStfrtITILLAAVGLILTPIYLLSML 411
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-201 3.42e-21

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 90.91  E-value: 3.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFmvLALWGVI--MTGSIC-LRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTG 77
Cdd:PRK06473 247 LLKLGTYGLLRFGVGLFPEAWVYLAPW--LATWAVVsvLYGASCaIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILA 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  78 AITLMIAHGLTSSMLFCLANTNYERTHSRTLLLAR---NMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNW 154
Cdd:PRK06473 325 AVFQMISHGLISALLFLLVGVVYKKTGSRDVDVLRgllNPERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPI 404

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 166987139 155 SNITILMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPPTHTREHL 201
Cdd:PRK06473 405 FPVQTLLCMIGTGLTAVYFLLLVNRVFFGRLTAELSNLPRVLWSERL 451
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-168 1.68e-20

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 88.67  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNP--LSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGA 78
Cdd:COG0651  247 LTKVGVYAILRVLTLLFGadPALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  79 ITLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN----W 154
Cdd:COG0651  327 LFHLLNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEagawL 406

                        170
                 ....*....|....
gi 166987139 155 SNITILMTGLGTLI 168
Cdd:COG0651  407 LAAVLLLSSLLTLA 420
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-192 4.17e-20

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 87.27  E-value: 4.17e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRItltLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:MTH00094 193 LLKLGTAGFLRI---LGSLNFVYNNFWIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGLM 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITIL 160
Cdd:MTH00094 270 MMLAHGYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSFF 349

                        170       180       190
                 ....*....|....*....|....*....|..
gi 166987139 161 MTGLGTLITATYTLYMLSTTQWGEMPSYIKMI 192
Cdd:MTH00094 350 FIFFYFLVSFYYSLFLIVSSFMGKKFSNFNNF 381
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-177 1.19e-19

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 86.54  E-value: 1.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPF-MVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:CHL00011 253 LLKMGAYGLIRINMELLPHAHSIFSPWlVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAI 332

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERThsRTLLLAR--NMQLLFPLMGLWWLLASLTNMALPPTINLMGELT----IITS--- 150
Cdd:CHL00011 333 LQIISHGFIGAALFFLAGTSYDRI--RLVYLDEmgGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIvffgIITSqky 410

                        170       180
                 ....*....|....*....|....*..
gi 166987139 151 LFNWSNITILMTGLGTLITATYTLYML 177
Cdd:CHL00011 411 LLMPKILITFVMAIGMILTPIYLLSML 437
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-177 1.48e-16

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 77.82  E-value: 1.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPFM-VLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:PRK02546 255 LLKMGGYALLRMNAGMLPDAHAQFAPLLiVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGAM 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHsrTLLL------ARNMQLLFPLmglwWLLASLTNMALPPTINLMGELTIITSL-- 151
Cdd:PRK02546 335 LQMISHGLIGASLFFLVGATYDRTH--TLMLdemggvGQKMRKMFAM----WTACSLASLALPGMSGFVAELMVFVGFat 408

                        170       180       190
                 ....*....|....*....|....*....|.
gi 166987139 152 -----FNWSNITILMTGLGTLITATYTLYML 177
Cdd:PRK02546 409 sdaytLPFRVVVVFLAAVGVILTPIYLLSML 439
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-213 4.70e-15

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 73.37  E-value: 4.70e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   3 KLGGYGIIRITLTL----NPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGA 78
Cdd:PRK08375 246 KVAVYALIRIYFTVfggdFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAG 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  79 ITLMIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLF-- 152
Cdd:PRK08375 326 LLHLLHHALMKGALFLAAGAIEVTYGTRRLSelsgLGRRM----PLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVea 401

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 166987139 153 -NWSNITILMtgLGTLITATYTLYMLSTTQWGEMPSYikmIPPTHTREHLLMMLHILPTTLL 213
Cdd:PRK08375 402 gQWLVLAVLL--ASSLLALLYFLRIWYRAFFGPPPPG---SEAPKQEAPLGMLAPSLALALL 458
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
1-194 5.02e-13

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 67.43  E-value: 5.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPLSKTLSYPfmVLALWGVI--MTGS-ICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTG 77
Cdd:PRK07363 247 LAKLGTYGLLRFGLQLFPQTWSLVAP--GLAIIGTIsvIYGAlSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLLG 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  78 AITLMIAHGLTSSMLFCLANTNYERTHSRTL-LLARNMQLL--FPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNW 154
Cdd:PRK07363 325 AVAQMISHGLILALLFHLVGIVERKVGTRDLdVLNGLMNPIrgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFST 404

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 166987139 155 SNITILMTGLGTLITATYTLYMLSTTQWGEMPSYIKMIPP 194
Cdd:PRK07363 405 FPIPTLLCIVASGLTAVYFVILLNRTCFGRLDNKLAYYPK 444
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-208 1.66e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 65.76  E-value: 1.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRI-------TLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQW 73
Cdd:PRK12667 265 VVNVGAYAIIRFlytifgiSPSLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQL 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  74 AHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN 153
Cdd:PRK12667 345 GLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLE 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 166987139 154 WSN-ITILMTGLGTLITATYTLYMLSTTQWGEMPSyikmIPPTHTREHLLMMLHIL 208
Cdd:PRK12667 425 SGFyLPALVLLIASAISLVGYFRAWYSLFFGKPKS----GEEVEHKESPSMSVVIL 476
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 1-214 7.83e-11

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 60.71  E-value: 7.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTL--NPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGA 78
Cdd:PRK06458 256 LLNVALYAVLRYYILIdaAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAA 335

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  79 ITLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN---WS 155
Cdd:PRK06458 336 LLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLArgpLL 415

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 166987139 156 NITILMTGLGTLITAtyTLYMLSTTQWGEmpsyikmiPPTHTREHLLMMLHILPTTLLM 214
Cdd:PRK06458 416 IAILLLLLLTLAFAA--LVRRVAGMVFGE--------PPEAVNRGDLGWLTTSPMFVHL 464
PRK12650 PRK12650
DUF4040 family protein;
36-195 1.62e-08

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 54.28  E-value: 1.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  36 IMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTL----LLA 111
Cdd:PRK12650 284 LMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIrrlgSLW 363

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 112 RNMQLLFPLMglwwLLASLTNMALPPTINLMGELTIITSLF-----NWSNITILMT-GLGTLITATYTL-YMLSTTQWGE 184
Cdd:PRK12650 364 RRMPFTFVSV----TIAALSMAAVPPLFGFVSKEGMLTAFLeapggNAGVVLLLVGaALGAVFTFAYSArLVLGAFVDGP 439

                        170
                 ....*....|..
gi 166987139 185 MP-SYIKMIPPT 195
Cdd:PRK12650 440 RDmSHVKEAPVS 451
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 3-179 3.40e-08

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 53.23  E-value: 3.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   3 KLGGYGIIRITLTLNPLSKTLSYPFMV--LALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:PRK08377 250 KAGLYAMARILYLMQNANGWSSVLKLViiMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVF 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  81 LMIAHGLTSSMLF--------CLANTNYERTHSrtllLARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLF 152
Cdd:PRK08377 330 HMINHAIVKALLFlavgyvgiTLGGTEIEKFEG----LGKRM----PLTALALTIGALSTVGIPLFNVFWSKFRIILAGL 401

                        170       180
                 ....*....|....*....|....*...
gi 166987139 153 NWSNITILMTGLG-TLITATYTLYMLST 179
Cdd:PRK08377 402 SAGYTWPVALVLGaSVVEAVYYFRLIHT 429
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 36-184 5.72e-08

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 52.46  E-value: 5.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  36 IMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQtqwAHTGAITLMIAHGLTSSMLFCLANTNYERTHSR--TLL--LA 111
Cdd:COG1009  287 LFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRdiRKMggLR 363

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 166987139 112 RNMQLLFPLMglwwLLASLTNMALPPTINLMGELTIITSLFNWSNITILMTGLGTL---ITATYTLYMLSTTQWGE 184
Cdd:COG1009  364 KKMPITAITF----LIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLLAVALLgafLTAFYSFRLFFLVFFGK 435
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 43-167 9.32e-08

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 51.84  E-value: 9.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  43 LRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMG 122
Cdd:PRK12647 278 VRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITA 357

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 166987139 123 LWWLLASLTNMALPPTINLMGELTIITSLFNWSNITILMTGLGTL 167
Cdd:PRK12647 358 AAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLILTVAAVL 402
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 3-167 4.62e-07

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 49.59  E-value: 4.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   3 KLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMG---LVIAATLTQTQWAHTGAI 79
Cdd:PRK06525 251 KVGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQLGymfFGLSLAILGSRLALEGSI 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNITI 159
Cdd:PRK06525 331 AYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVPPFNGFFSKFPIFAAGFELSVEYW 410


                 ....*...
gi 166987139 160 LMTGLGTL 167
Cdd:PRK06525 411 ILLPAMVL 418
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-169 8.34e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 48.79  E-value: 8.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   3 KLGGYGIIRITLTLNPLSKTLSYPFMVLALWGVImtgsICLRQTDLKSLIAYSSVSHMGLVIAATLtqtqwahTGAItLM 82
Cdd:PRK07234 228 KAGVFPLVRCALDVPGLDLIVRIFGVGTALLGVL----FALLEKDLKRMLAFSTISQLGFILAAPL-------VGGL-YA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  83 IAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLmglwwLLASLTNMALPPTINLMGELTIITSLFNWSNITILMT 162
Cdd:PRK07234 296 LAHGLVKSTLFLCAGALPSRNFTELISQMLGIGKWIPL-----TMASFSIAGFPLLAGFVSKVLTLKNLLPWQAIALNLA 370


                 ....*..
gi 166987139 163 GLGTLIT 169
Cdd:PRK07234 371 AVGTAAS 377
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 23-163 1.24e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 48.58  E-value: 1.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  23 LSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANT---N 99
Cdd:PRK12662 278 FNNVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyH 357

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 166987139 100 YERTHSRTLL-LARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN---WSNITILMTG 163
Cdd:PRK12662 358 FGTTKLEDCLnLWKSM----PKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKsnaWIGLVVLLVG 421
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 29-183 2.62e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 47.61  E-value: 2.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  29 VLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTL 108
Cdd:PRK12644 272 VLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALFLVVGIIDHSTGTRDI 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 109 L----LARNMqllfPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN------WSNITILMTGLGTLITATYTLYMLs 178
Cdd:PRK12644 352 RklsgLGRRQ----PVLAVVAALAAASMAGLPPLLGFVAKEAALEAVLHdgalgpAGPVVLAGIVLGSILTVAYSLRFL- 426


                 ....*
gi 166987139 179 ttqWG 183
Cdd:PRK12644 427 ---WG 428
PRK12646 PRK12646
DUF4040 family protein;
1-215 3.53e-06

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 47.06  E-value: 3.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNpLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIA--------ATLTQTQ 72
Cdd:PRK12646 252 MVKAGIFLLFRFTPLLG-LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAmvgigggyAQHQQDA 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  73 WAHTGAITL------MIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELT 146
Cdd:PRK12646 331 IASIYVFVLfaalfhLMNHAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEM 410

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 166987139 147 IITSLFNWSNI-------TILMTGLG---TLITATYTLYMLSTTQWGEMPSyiKMIPPTHTREHLLMMlhiLPTTLLMM 215
Cdd:PRK12646 411 FLDALTQTGQLsqfslisMIIIVFIGviaSIFTFTYALYMVKEVFWGKYDS--KVFTKKNIHEPWLFS---LPSLILMV 484
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 1-152 4.23e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 47.03  E-value: 4.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLnpLSKTLSYPFMVL------ALWGVIMTgsicLRQTDLKSLIAYSSVSHMGLV----------- 63
Cdd:PRK08667 247 MLKVAVYGLVRFLMDV--LSPELWWGVLILlagsisALLGVIYA----LKEHDLKGLLAYSSIENIGIIlmgiglyvifg 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  64 IAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMG 143
Cdd:PRK08667 321 VYGLDTLALLALGGALFHSLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFAS 400


                 ....*....
gi 166987139 144 ELTIITSLF 152
Cdd:PRK08667 401 ELLLYESFF 409
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-190 2.02e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 44.81  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  31 ALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTLLL 110
Cdd:PRK06589 287 PIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQVDK 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 111 ARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWSNIT--ILMTGLGTLITATYTLYMLSTTQWGEMPSY 188
Cdd:PRK06589 367 LHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWlsIIVMLVVIASSILSALYLLKILSSIYKPSL 446


                 ..
gi 166987139 189 IK 190
Cdd:PRK06589 447 SE 448
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-93 2.53e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 44.36  E-value: 2.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTL--NPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGA 78
Cdd:PRK08676 248 VLNIGIYGILRLSALLrqSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWM 327

                         90
                 ....*....|....*
gi 166987139  79 ITLMIAHGLTSSMLF 93
Cdd:PRK08676 328 LFHMLAHSLVKSGLF 342
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 1-93 2.82e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 44.22  E-value: 2.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIrITLTLNPLSK------------TLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATL 68
Cdd:PRK08668 238 LSKLGAYGFL-LVLYVLPGTKlfsefgtyrgvpLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLG 316

                         90       100
                 ....*....|....*....|....*
gi 166987139  69 TQTQWAHTGAITLMIAHGLTSSMLF 93
Cdd:PRK08668 317 LGTSLGFAGGLFHVFNHALFKGLFF 341
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 3-89 6.43e-05

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 43.18  E-value: 6.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   3 KLGGYGI-IRITLT-LNPLSKTLSYPFMVLALwgVIMT-GSIC-LRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGA 78
Cdd:COG1007  246 KIAAFAAlLRLLVEaFPGLAADWQLLLAVLAV--LSMTvGNLAaLAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAA 323

                         90
                 ....*....|.
gi 166987139  79 ITLMIAHGLTS 89
Cdd:COG1007  324 LFYLLAYLFMN 334
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
43-89 1.67e-04

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 42.12  E-value: 1.67e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 166987139  43 LRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTS 89
Cdd:PRK05777 289 LSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMT 335
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 2-137 3.97e-04

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 41.03  E-value: 3.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   2 LKLGGYGIIRITLTL-NPLSKTLSYPFMVL----ALWGVIMTgsicLRQTDLKSLIAYSSVSHMGLVI------------ 64
Cdd:PRK06521 253 LKVAIYGILRVVFDLlGAPGWWWGVLVLALgaisAVLGVLYA----LAEHDLKRLLAYSTIENIGIIFvglglamvfiay 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  65 ----AATLtqtqwAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMqllfPLMGLWWLLASLTNMALP 136
Cdd:PRK06521 329 gmplLAAL-----ALTAALYHLLNHALFKSLLFLGAGAVLHATGTRDMEklggLIRRM----PWTAWAFLIGCLAISALP 399


                 .
gi 166987139 137 P 137
Cdd:PRK06521 400 P 400
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 20-178 9.60e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 39.48  E-value: 9.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  20 SKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTqwaHTGAITLMIAHGLTSSMLFCLANTN 99
Cdd:MTH00144 140 LYWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGS---WLMWMYFLIYIVSSGFLFFSLWSGD 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139 100 YERTHSRTlllarnMQLLFPLMGLWWLLASLTNMALPPTINLMGELTIITSLFNWS-NITILMTGLGTLITATYTLYMLS 178
Cdd:MTH00144 217 SGSMKDLG------SLKPSYKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSpLLLILLLLLGSLISLFFYLSVFF 290
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-167 1.31e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 39.16  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRI-TLTLNPLSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAI 79
Cdd:PRK07691 251 LTKVGVYAIARTfTLFFSHDTSFTHYLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAI 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  80 TLMIAHGLTSSMLFCLANTNYERTHSRTLllaRNMQLL---FPLMGLWWLLASLTNMALPPTINLMGELTIITSLFN--- 153
Cdd:PRK07691 331 YYLIHDMIVKAALFLLIGIMIKITGTTDL---KKMGGLikrYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEagf 407

                        170
                 ....*....|....*
gi 166987139 154 -WSNITILMTGLGTL 167
Cdd:PRK07691 408 yVSGIIVLLSSLLVL 422
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
28-137 1.91e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 38.86  E-value: 1.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139  28 MVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAITLMIAHGLTSSMLFCLANTNYERTHSRT 107
Cdd:PRK06277 270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                         90       100       110
                 ....*....|....*....|....*....|
gi 166987139 108 LLLARNMQLLFPLMGLWWLLASLTNMALPP 137
Cdd:PRK06277 350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPP 379
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 5-137 2.24e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 38.54  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   5 GGYGIIRITLTLNPLS---KTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVI------AATLTQTQWAH 75
Cdd:PRK08376 265 GLYALARVLFSIYGPAinlATVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglgvgLAALGDPAMAS 344

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 166987139  76 TGAITL------MIAHGLTSSMLFCLANTNYERTHSRTLL----LARNMqllfPLMGLWWLLASLTNMALPP 137
Cdd:PRK08376 345 YGEIALaggiyhIVNHALYKALLFLTAGAVIYETGTRNLNelggLARTM----PKTTIAFLIGAAAIVGLPP 412
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-148 2.89e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 38.03  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166987139   1 LLKLGGYGIIRITLTLNPlSKTLSYPFMVLALWGVIMTGSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWAHTGAIT 80
Cdd:PRK12665 251 LTKVGVYAIIRTHTLLFP-GGGLDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGLSGAIY 329

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 166987139  81 LMIAHGLTSSMLFCLANTNYERTHSRTLLLARNMQLLFPLMGLWWLLASLTNMALPPTINLMGELTII 148
Cdd:PRK12665 330 YVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALL 397
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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