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Conserved domains on  [gi|166089708|dbj|BAG04416|]
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uracil phosphoribosyltransferase [Microcystis aeruginosa NIES-843]

Protein Classification

bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase( domain architecture ID 10788351)

bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PyrR COG2065
Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide ...
 7-177 4.40e-100

Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine salvage


:

Pssm-ID: 441668  Cd Length: 178  Bit Score: 285.80  E-value: 4.40e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   7 EILSADEIRRTITRLASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITFYRDDLDRIKTRT-P 85
Cdd:COG2065    5 EILDAADIDRALTRIAHEIIERNKGLEDLVLVGIQTRGVPLAERLAERIEEIEGVKVPVGSLDITLYRDDLRRRPPRPvV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  86 AKTKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGRPQKIRLLVLVDRGHRELPIHPDFTGKKLPTAAEEQVKVYLQ 165
Cdd:COG2065   85 NETEIPFDIDGKTVVLVDDVLYTGRTVRAALDALMDFGRPAKIQLAVLVDRGHRELPIRADYVGKNVPTSRSERVEVRLK 164

                        170
                 ....*....|..
gi 166089708 166 EIDGKDGVELIK 177
Cdd:COG2065  165 EIDGEDAVVIVE 176
 
Name Accession Description Interval E-value
PyrR COG2065
Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide ...
 7-177 4.40e-100

Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 441668  Cd Length: 178  Bit Score: 285.80  E-value: 4.40e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   7 EILSADEIRRTITRLASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITFYRDDLDRIKTRT-P 85
Cdd:COG2065    5 EILDAADIDRALTRIAHEIIERNKGLEDLVLVGIQTRGVPLAERLAERIEEIEGVKVPVGSLDITLYRDDLRRRPPRPvV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  86 AKTKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGRPQKIRLLVLVDRGHRELPIHPDFTGKKLPTAAEEQVKVYLQ 165
Cdd:COG2065   85 NETEIPFDIDGKTVVLVDDVLYTGRTVRAALDALMDFGRPAKIQLAVLVDRGHRELPIRADYVGKNVPTSRSERVEVRLK 164

                        170
                 ....*....|..
gi 166089708 166 EIDGKDGVELIK 177
Cdd:COG2065  165 EIDGEDAVVIVE 176
PRK05205 PRK05205
bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR;
6-177 6.63e-99

bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR;


Pssm-ID: 235365  Cd Length: 176  Bit Score: 282.79  E-value: 6.63e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   6 IEILSADEIRRTITRLASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITFYRDDL-DRIKTRT 84
Cdd:PRK05205   4 KEILDAEALRRALTRIAHEIIERNKGLDNLVLVGIKTRGVWLAERLAERLEQLEGVDVPVGELDITLYRDDLtKKGLHPQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  85 PAKTKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGRPQKIRLLVLVDRGHRELPIHPDFTGKKLPTAAEEQVKVYL 164
Cdd:PRK05205  84 VKPTDIPFDIEGKRVILVDDVLYTGRTIRAALDALFDYGRPARVQLAVLVDRGHRELPIRADYVGKNIPTSRDERVVVRL 163

                        170
                 ....*....|...
gi 166089708 165 QEIDGKDGVELIK 177
Cdd:PRK05205 164 AEVDGRDRVVLER 176
Pribosyltran pfam00156
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ...
 7-143 6.64e-17

Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.


Pssm-ID: 425489 [Multi-domain]  Cd Length: 150  Bit Score: 73.17  E-value: 6.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708    7 EILSADEIRRTITRLASEVIEkSGDLNNLILIGIYTRGVPLANLIASQIEslegvkVPVGAIDITFYRDDldrikTRTPA 86
Cdd:pfam00156   4 EILDNPAILKAVARLAAQINE-DYGGKPDVVVGILRGGLPFAGILARRLD------VPLAFVRKVSYNPD-----TSEVM 71

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 166089708   87 KTK-MPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGHRELPI 143
Cdd:pfam00156  72 KTSsALPDLKGKTVLIVDDILDTGGTLLKVLELLKNVG-PKEVKIAVLIDKPAGTEPK 128
PRTases_typeI cd06223
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ...
 18-149 2.45e-15

Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.


Pssm-ID: 206754 [Multi-domain]  Cd Length: 130  Bit Score: 68.58  E-value: 2.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  18 ITRLASEVIEKSGDlnNLILIGIYTRGVPLANLIASQIeslegvKVPVGAIDITFYRDDLDRIKTRTPAKtKMPLDVTGK 97
Cdd:cd06223    2 GRLLAEEIREDLLE--PDVVVGILRGGLPLAAALARAL------GLPLAFIRKERKGPGRTPSEPYGLEL-PLGGDVKGK 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 166089708  98 TVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGHR-----ELPIHPDFTG 149
Cdd:cd06223   73 RVLLVDDVIATGGTLLAAIELLKEAG-AKVVGVAVLLDKPEGgarelASPGDPVYSL 128
 
Name Accession Description Interval E-value
PyrR COG2065
Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide ...
 7-177 4.40e-100

Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 441668  Cd Length: 178  Bit Score: 285.80  E-value: 4.40e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   7 EILSADEIRRTITRLASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITFYRDDLDRIKTRT-P 85
Cdd:COG2065    5 EILDAADIDRALTRIAHEIIERNKGLEDLVLVGIQTRGVPLAERLAERIEEIEGVKVPVGSLDITLYRDDLRRRPPRPvV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  86 AKTKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGRPQKIRLLVLVDRGHRELPIHPDFTGKKLPTAAEEQVKVYLQ 165
Cdd:COG2065   85 NETEIPFDIDGKTVVLVDDVLYTGRTVRAALDALMDFGRPAKIQLAVLVDRGHRELPIRADYVGKNVPTSRSERVEVRLK 164

                        170
                 ....*....|..
gi 166089708 166 EIDGKDGVELIK 177
Cdd:COG2065  165 EIDGEDAVVIVE 176
PRK05205 PRK05205
bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR;
6-177 6.63e-99

bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR;


Pssm-ID: 235365  Cd Length: 176  Bit Score: 282.79  E-value: 6.63e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   6 IEILSADEIRRTITRLASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITFYRDDL-DRIKTRT 84
Cdd:PRK05205   4 KEILDAEALRRALTRIAHEIIERNKGLDNLVLVGIKTRGVWLAERLAERLEQLEGVDVPVGELDITLYRDDLtKKGLHPQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  85 PAKTKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGRPQKIRLLVLVDRGHRELPIHPDFTGKKLPTAAEEQVKVYL 164
Cdd:PRK05205  84 VKPTDIPFDIEGKRVILVDDVLYTGRTIRAALDALFDYGRPARVQLAVLVDRGHRELPIRADYVGKNIPTSRDERVVVRL 163

                        170
                 ....*....|...
gi 166089708 165 QEIDGKDGVELIK 177
Cdd:PRK05205 164 AEVDGRDRVVLER 176
Pribosyltran pfam00156
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ...
 7-143 6.64e-17

Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.


Pssm-ID: 425489 [Multi-domain]  Cd Length: 150  Bit Score: 73.17  E-value: 6.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708    7 EILSADEIRRTITRLASEVIEkSGDLNNLILIGIYTRGVPLANLIASQIEslegvkVPVGAIDITFYRDDldrikTRTPA 86
Cdd:pfam00156   4 EILDNPAILKAVARLAAQINE-DYGGKPDVVVGILRGGLPFAGILARRLD------VPLAFVRKVSYNPD-----TSEVM 71

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 166089708   87 KTK-MPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGHRELPI 143
Cdd:pfam00156  72 KTSsALPDLKGKTVLIVDDILDTGGTLLKVLELLKNVG-PKEVKIAVLIDKPAGTEPK 128
PRTases_typeI cd06223
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ...
 18-149 2.45e-15

Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.


Pssm-ID: 206754 [Multi-domain]  Cd Length: 130  Bit Score: 68.58  E-value: 2.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  18 ITRLASEVIEKSGDlnNLILIGIYTRGVPLANLIASQIeslegvKVPVGAIDITFYRDDLDRIKTRTPAKtKMPLDVTGK 97
Cdd:cd06223    2 GRLLAEEIREDLLE--PDVVVGILRGGLPLAAALARAL------GLPLAFIRKERKGPGRTPSEPYGLEL-PLGGDVKGK 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 166089708  98 TVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGHR-----ELPIHPDFTG 149
Cdd:cd06223   73 RVLLVDDVIATGGTLLAAIELLKEAG-AKVVGVAVLLDKPEGgarelASPGDPVYSL 128
Hpt1 COG2236
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ...
 1-154 2.26e-13

Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage


Pssm-ID: 441837 [Multi-domain]  Cd Length: 153  Bit Score: 64.10  E-value: 2.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   1 MTPQLIEILSADEIRRTITRLASEVIEKSGDLNnlILIGIYTRGVPLANLIASQIesleGVKVpVGAIDITFYRDDldrI 80
Cdd:COG2236    1 MDKFKKEYLSWDEIHELSRRLAEQILESGFRPD--VIVAIARGGLVPARILADAL----GVPD-LASIRVSSYTGT---A 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 166089708  81 KTRTPAKTKMPLD--VTGKTVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGHRElpIHPDFTGKKLPT 154
Cdd:COG2236   71 KRLEEPVVKGPLDedLAGKRVLIVDDVADTGRTLEAVRDLLKEAG-PAEVRTAVLYYKPSSK--FKPDYYAEETDA 143
HptA COG0634
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; ...
 1-153 3.22e-10

Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Hypoxanthine-guanine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage


Pssm-ID: 440399  Cd Length: 176  Bit Score: 56.19  E-value: 3.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   1 MTPQLIEIL-SADEIRRTITRLASEVIEKSGDlNNLILIGIYTRGVPLANLIASQIEslegVKVPVGAIDITFYRDDLD- 78
Cdd:COG0634    1 MHDDIAEVLiSEEEIQARVKELAAQITADYAG-KEPLVVGVLKGAFVFMADLLRALD----FPLEIDFMHVSSYGGGTEs 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  79 ----RIKTrtpaktKMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLVDRGH-RELPIHPDFTGKKLP 153
Cdd:COG0634   76 sgevRILK------DLDEDIEGRDVLIVEDIIDTGLTLSYLLELLKSRG-PASVKIATLLDKPErRKVDVPADYVGFEIP 148
PRK09162 PRK09162
hypoxanthine-guanine phosphoribosyltransferase; Provisional
 7-149 5.14e-07

hypoxanthine-guanine phosphoribosyltransferase; Provisional


Pssm-ID: 181675  Cd Length: 181  Bit Score: 47.16  E-value: 5.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708   7 EILSADEIRRTITRLASEVIEKSGDLNNLILIgIYTRGVPLANLIASQIES-LEgvkvpVGAIDITFYRDdldriKTRTP 85
Cdd:PRK09162  15 CLVSAAEVEAAIDRMADEITADLADENPLVLC-VMGGGLVFTGQLLPRLDFpLE-----FDYLHATRYRN-----ETTGG 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 166089708  86 A---KTKMPLDVTGKTVILVDDVIYKGRTIRAafnaIIEYGR---PQKIRLLVLVDRGH-RELP-IHPDFTG 149
Cdd:PRK09162  84 ElvwKVKPRESLKGRTVLVVDDILDEGHTLAA----IRDRCLemgAAEVYSAVLVDKTHdRKAKpLKADFVG 151
PRK06031 PRK06031
phosphoribosyltransferase; Provisional
 21-115 4.94e-06

phosphoribosyltransferase; Provisional


Pssm-ID: 235678  Cd Length: 233  Bit Score: 45.13  E-value: 4.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  21 LASEVIEKSGDLNNLILIGIYTRGVPLANLIASQIEslEGVKVPVGAIDITFYRDDLD---RIKTrTPAKTKM------- 90
Cdd:PRK06031  72 LAEHLAEKARAFDPDVVAGLPTLGLTLAAAVARKLG--HTRYVPLGTSRKFWYRDELSvplSSIT-TPDQGKRlyidprm 148

                         90       100
                 ....*....|....*....|....*.
gi 166089708  91 -PLdVTGKTVILVDDVIYKGRTIRAA 115
Cdd:PRK06031 149 lPL-LEGRRVALIDDVISSGASIVAG 173
PRK02277 PRK02277
orotate phosphoribosyltransferase-like protein; Provisional
 16-145 6.75e-06

orotate phosphoribosyltransferase-like protein; Provisional


Pssm-ID: 235023 [Multi-domain]  Cd Length: 200  Bit Score: 44.47  E-value: 6.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 166089708  16 RTITRLASEVIEKSGDLNNLIlIGIYTRGVPLANLIASQIESLEGVKVPVGAIDITfyRDDLDRIKTRTPAKtkmpldVT 95
Cdd:PRK02277  69 RYIASAMADMLEKEDEEVDVV-VGIAKSGVPLATLVADELGKDLAIYHPKKWDHGE--GEKKTGSFSRNFAS------VE 139

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 166089708  96 GKTVILVDDVIYKGRTIRAAFNAIIEYG-RPQKIrlLVLVD-RGHREL---PIHP 145
Cdd:PRK02277 140 GKRCVIVDDVITSGTTMKETIEYLKEHGgKPVAV--VVLIDkSGIDEIdgvPVYS 192
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 93-123 5.39e-04

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 39.27  E-value: 5.39e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 166089708  93 DVTGKTVILVDDVIYKGRTIRAAFNAIIEYG 123
Cdd:COG0462  208 DVEGKTCIIVDDMIDTGGTLVEAAEALKEAG 238
COG1926 COG1926
Predicted phosphoribosyltransferase [General function prediction only];
91-133 5.90e-04

Predicted phosphoribosyltransferase [General function prediction only];


Pssm-ID: 441529  Cd Length: 209  Bit Score: 38.90  E-value: 5.90e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 166089708  91 PLDVTGKTVILVDDVIYKGRTIRAAfnaiIEYGRPQKIRLLVL 133
Cdd:COG1926  116 PPDLKGRTVILVDDGIATGATMRAA----LRALRRQGPARIVV 154
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
93-123 1.62e-03

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 37.79  E-value: 1.62e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 166089708  93 DVTGKTVILVDDVIYKGRTIRAAFNAIIEYG 123
Cdd:PRK01259 205 DVEGRDCILVDDMIDTAGTLCKAAEALKERG 235
upp PRK00129
uracil phosphoribosyltransferase; Reviewed
 89-134 3.26e-03

uracil phosphoribosyltransferase; Reviewed


Pssm-ID: 234653  Cd Length: 209  Bit Score: 36.60  E-value: 3.26e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 166089708  89 KMPLDVTGKTVILVDDVIYKGRTIRAAFNAIIEYGrPQKIRLLVLV 134
Cdd:PRK00129 117 KLPEDIDERTVIVVDPMLATGGSAIAAIDLLKKRG-AKNIKVLCLV 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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