NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1656133219|ref|WP_137963149|]
View 

AlpA family transcriptional regulator, partial [Klebsiella variicola]

Protein Classification

helix-turn-helix transcriptional regulator( domain architecture ID 10007181)

helix-turn-helix DNA-binding protein similar to Mycobacterium phage excisionase, which is necessary for the excision of prophage from the host genome by site-specific recombination at the attachment site

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0003700|GO:0006355
PubMed:  15808743|10473770|8831795

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AlpA COG3311
DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];
4-29 1.03e-04

DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];


:

Pssm-ID: 442540 [Multi-domain]  Cd Length: 64  Bit Score: 37.22  E-value: 1.03e-04
                          10        20
                  ....*....|....*....|....*.
gi 1656133219   4 VSISEAARLTGKSRTTLHRLIKAGDL 29
Cdd:COG3311     9 LRLKEVAELLGVSRSTIYRLIKKGEF 34
 
Name Accession Description Interval E-value
AlpA COG3311
DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];
4-29 1.03e-04

DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];


Pssm-ID: 442540 [Multi-domain]  Cd Length: 64  Bit Score: 37.22  E-value: 1.03e-04
                          10        20
                  ....*....|....*....|....*.
gi 1656133219   4 VSISEAARLTGKSRTTLHRLIKAGDL 29
Cdd:COG3311     9 LRLKEVAELLGVSRSTIYRLIKKGEF 34
HTH_17 pfam12728
Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.
 5-29 7.99e-04

Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.


Pssm-ID: 463684 [Multi-domain]  Cd Length: 51  Bit Score: 34.74  E-value: 7.99e-04
                          10        20
                  ....*....|....*....|....*
gi 1656133219   5 SISEAARLTGKSRTTLHRLIKAGDL 29
Cdd:pfam12728   3 TVEEAAELLGVSRRTVYRLIRSGEL 27
 
Name Accession Description Interval E-value
AlpA COG3311
DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];
4-29 1.03e-04

DNA-binding transcriptional regulator AlpA [Transcription, Mobilome: prophages, transposons];


Pssm-ID: 442540 [Multi-domain]  Cd Length: 64  Bit Score: 37.22  E-value: 1.03e-04
                          10        20
                  ....*....|....*....|....*.
gi 1656133219   4 VSISEAARLTGKSRTTLHRLIKAGDL 29
Cdd:COG3311     9 LRLKEVAELLGVSRSTIYRLIKKGEF 34
HTH_17 pfam12728
Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.
 5-29 7.99e-04

Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.


Pssm-ID: 463684 [Multi-domain]  Cd Length: 51  Bit Score: 34.74  E-value: 7.99e-04
                          10        20
                  ....*....|....*....|....*
gi 1656133219   5 SISEAARLTGKSRTTLHRLIKAGDL 29
Cdd:pfam12728   3 TVEEAAELLGVSRRTVYRLIRSGEL 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH