|
Name |
Accession |
Description |
Interval |
E-value |
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
513-744 |
1.16e-85 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 272.46 E-value: 1.16e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYddkkdfllsRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSED 592
Cdd:cd03263 1 LQIRNLTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DgSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:cd03263 72 A-ARQSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK 744
Cdd:cd03263 151 GPSVLLLDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
513-747 |
3.41e-69 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 228.79 E-value: 3.41e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETsED 592
Cdd:COG1131 1 IEVRGLTKRYGDK-----------TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVAR-DP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:COG1131 69 AEVRRRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLH 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRF 747
Cdd:COG1131 149 DPELLILDEPTSGLDPEARRELWELLR-ELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
280-841 |
1.01e-65 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 240.69 E-value: 1.01e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 280 LSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFkkilntkEF 359
Cdd:TIGR01257 1715 ISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLF-------DV 1787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 360 WSFIYsvAALAC------IAITEITFFMGY--TIATILHY-----AFCIIIPIYPLLGCLISfIKISwknvRKNVDTY-- 424
Cdd:TIGR01257 1788 PSTAY--VALSCanlfigINSSAITFVLELfeNNRTLLRFnamlrKLLIVFPHFCLGRGLID-LALS----QAVTDVYaq 1860
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 425 -------NP--WDRLSVAVISPHLQCVLWIFLLQYYEKKYggrsirkdpFFrnlstkskNRKLPEPPDNE--DEDEDVKA 493
Cdd:TIGR01257 1861 fgeehsaNPfqWDLIGKNLVAMAVEGVVYFLLTLLIQHHF---------FL--------SRWIAEPAKEPifDEDDDVAE 1923
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 494 ERLKVkeLMGcqcceekpsimvsnlhkeyDDKKDFLLSRKVKKV-------ATKYISFCVKKGEILGLLGPNGAGKSTII 566
Cdd:TIGR01257 1924 ERQRI--ISG-------------------GNKTDILRLNELTKVysgtsspAVDRLCVGVRPGECFGLLGVNGAGKTTTF 1982
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 567 NILVGDIEPTSGQVFLGDYSSETSEDDGSlKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLK 646
Cdd:TIGR01257 1983 KMLTGDTTVTSGDATVAGKSILTNISDVH-QNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLS 2061
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 647 EHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKnRKRAAILTTHYMEEAEAVCDRV 726
Cdd:TIGR01257 2062 LYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIR-EGRAVVLTSHSMEECEALCTRL 2140
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 727 AIMVSGQLRCIGTVQHLKSRFGKGYFLEIKLKDWIENL--EVDRLQREIQYIFPNASRQESFSSILAYKIPKedvQSLSQ 804
Cdd:TIGR01257 2141 AIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSPKDDLlpDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSS---SSLAR 2217
|
570 580 590
....*....|....*....|....*....|....*..
gi 16551961 805 SFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEE 841
Cdd:TIGR01257 2218 IFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAKQQTE 2254
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
513-749 |
5.60e-57 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 195.85 E-value: 5.60e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDdkkdfllsrkvKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSeTSED 592
Cdd:COG4555 2 IEVENLSKKYG-----------KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDV-RKEP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:COG4555 70 REARRQIGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVH 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGK 749
Cdd:COG4555 150 DPKVLLLDEPTNGLDVMARRLLREILR-ALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
537-836 |
8.90e-55 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 191.83 E-value: 8.90e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSeTSEDDGSLKCMGYCPQINPLWPDTTLQE 616
Cdd:TIGR01188 7 KAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV-VREPRKVRRSIGIVPQYASVDEDLTGRE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWR 696
Cdd:TIGR01188 86 NLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 697 AIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGKGyFLEIKLKDWIE-NLEVDRLQREIQY 775
Cdd:TIGR01188 166 YIR-ALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKD-TLESRPRDIQSlKVEVSMLIAELGE 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 776 IFPNASRQESFSSILAYKIPKEDVQsLSQSFFKLEEAKhaFAIEEYSFSQATLEQVFVELT 836
Cdd:TIGR01188 244 TGLGLLAVTVDSDRIKILVPDGDET-VPEIVEAAIRNG--IRIRSISTERPSLDDVFLKLT 301
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
513-744 |
4.35e-54 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 186.81 E-value: 4.35e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSeTSED 592
Cdd:cd03265 1 IEVENLVKKYGDF-----------EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDV-VREP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:cd03265 69 REVRRRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVH 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK 744
Cdd:cd03265 149 RPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
515-734 |
3.31e-50 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 174.12 E-value: 3.31e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDg 594
Cdd:cd03230 3 VRNLSKRYGKKT-----------ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEE- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 SLKCMGYCPQINPLWPDTTLQEHFeiygavkgmsasdmkevisrithgldlkehlqktvkKLPAGIKRKLCFALSMLGNP 674
Cdd:cd03230 71 VKRRIGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDP 114
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03230 115 ELLILDEPTSGLDPESRREFWELLRE-LKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
515-841 |
1.86e-45 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 165.28 E-value: 1.86e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysseTSEDDG 594
Cdd:COG4152 4 LKGLTKRFGDKT-----------AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDG----EPLDPE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 SLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNP 674
Cdd:COG4152 69 DRRRIGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGKGYFlE 754
Cdd:COG4152 149 ELLILDEPFSGLDPVNVELLKDVIR-ELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTL-R 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 755 IKLK---DWIENLevdrlqreiqyifPNASRQESFSSILAYKIPKE-DVQSLsqsffkLEEAKHAFAIEEYSFSQATLEQ 830
Cdd:COG4152 227 LEADgdaGWLRAL-------------PGVTVVEEDGDGAELKLEDGaDAQEL------LRALLARGPVREFEEVRPSLNE 287
|
330
....*....|.
gi 16551961 831 VFVELTKEQEE 841
Cdd:COG4152 288 IFIEVVGEKAE 298
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
513-768 |
2.63e-44 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 162.95 E-value: 2.63e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDK----------KDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVfl 582
Cdd:COG4586 2 IEVENLSKTYRVYekepglkgalKGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 583 gdyssetseddgslKCMGYCP----------------QINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLK 646
Cdd:COG4586 80 --------------RVLGYVPfkrrkefarrigvvfgQRSQLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 647 EHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfkNRKRAA--ILTTHYMEEAEAVCD 724
Cdd:COG4586 146 ELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEY--NRERGTtiLLTSHDMDDIEALCD 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 16551961 725 RVAIMVSGQLRCIGTVQHLKSRFGKGYFLEIKLKDWIENLEVDR 768
Cdd:COG4586 224 RVIVIDHGRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPR 267
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
536-738 |
3.67e-43 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 155.90 E-value: 3.67e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 536 KVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSEDDGSlkcMGYCPQINPLWPDTTLQ 615
Cdd:cd03269 13 VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLF-DGKPLDIAARNR---IGYLPEERGLYPKMKVI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMW 695
Cdd:cd03269 89 DQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLK 168
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 696 RAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03269 169 DVIRE-LARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
513-735 |
4.28e-40 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 146.95 E-value: 4.28e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDdkkdfllsrkvKKVATKYISFCVKKGeILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSeTSED 592
Cdd:cd03264 1 LQLENLTKRYG-----------KKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDV-LKQP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:cd03264 68 QKLRRRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVG 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 673 NPQITLLDEPSTGMDPKAkqhmwraiRTAFKN------RKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:cd03264 148 DPSILIVDEPTAGLDPEE--------RIRFRNllselgEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
513-734 |
1.36e-39 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 146.71 E-value: 1.36e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYD----------DKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL 582
Cdd:cd03267 1 IEVSNLSKSYRvyskepgligSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 583 GDYSSeTSEDDGSLKCMGYC-PQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIK 661
Cdd:cd03267 81 AGLVP-WKRRKKFLRRIGVVfGQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 662 RKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03267 160 MRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
512-732 |
1.95e-38 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 146.51 E-value: 1.95e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGdySSETS 590
Cdd:PRK13536 41 AIDLAGVSKSYGDK-----------AVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKItVLG--VPVPA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSM 670
Cdd:PRK13536 108 RARLARARIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARAL 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 671 LGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG 732
Cdd:PRK13536 188 INDPQLLILDEPTTGLDPHARHLIWERLR-SLLARGKTILLTTHFMEEAERLCDRLCVLEAG 248
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
513-738 |
8.25e-38 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 140.97 E-value: 8.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLlsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSED 592
Cdd:cd03266 2 ITADALTKRFRDVKKTV-------QAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKcMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLG 672
Cdd:cd03266 75 EARRR-LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03266 154 DPPVLLLDEPTTGLDVMATRALREFIR-QLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
530-735 |
1.45e-37 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 139.66 E-value: 1.45e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 530 LSRKVKKV-ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSEDDGSLKCMGYCPQinp 607
Cdd:cd03268 6 LTKTYGKKrVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEItFDGKSYQKNIEALRRIGALIEAPG--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 608 LWPDTTLQEHFEIYGAVKGMSASDMKEVISRIthglDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:cd03268 83 FYPNLTARENLRLLARLLGIRKKRIDEVLDVV----GLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLD 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 16551961 688 PKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:cd03268 159 PDGIKELRELIL-SLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
511-733 |
1.80e-37 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 142.64 E-value: 1.80e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETS 590
Cdd:PRK13537 6 APIDFRNVEKRYGDK-----------LVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDGSLKcMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSM 670
Cdd:PRK13537 75 ARHARQR-VGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 671 LGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKnRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:PRK13537 154 VNDPDVLVLDEPTTGLDPQARHLMWERLRSLLA-RGKTILLTTHFMEEAERLCDRLCVIEEGR 215
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
325-849 |
2.05e-37 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 152.48 E-value: 2.05e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 325 FLAVVFCLIG----YVPSVILFTYIASFTFKKILNTKEFWSFiYSVAALA--CIAITEITFFMGYT--------IATILH 390
Cdd:TIGR01257 713 FLLTIFIMHGrilhYSDPFILFLFLLAFSTATIMQCFLLSTF-FSKASLAaaCSGVIYFTLYLPHIlcfawqdrMTADLK 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 391 YAFCIIIPIYPLLGC--LISF----IKISWKNVRKNV---DTYNPWDRLSVAVISPHLQCVLWIFLLQYYEKKYG----- 456
Cdd:TIGR01257 792 TAVSLLSPVAFGFGTeyLVRFeeqgLGLQWSNIGNSPlegDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGtplpw 871
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 457 -------------GRSIRKDPFFRNLSTKSKNRKLPEPPDNEDedeDVKAERlkvkELMGCQcceekPSIMVSNLHKEYD 523
Cdd:TIGR01257 872 yfllqesywlggeGCSTREERALEKTEPLTEEMEDPEHPEGIN---DSFFER----ELPGLV-----PGVCVKNLVKIFE 939
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 524 dkkdfllsrKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDdGSLKCMGYCP 603
Cdd:TIGR01257 940 ---------PSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLD-AVRQSLGMCP 1009
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 604 QINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 683
Cdd:TIGR01257 1010 QHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPT 1089
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 684 TGMDPKAKQHMWRAIrtaFKNRK-RAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGKGYFLEI--KLK-- 758
Cdd:TIGR01257 1090 SGVDPYSRRSIWDLL---LKYRSgRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLvrKMKni 1166
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 759 -------------------------------DWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQ--SLSQS 805
Cdd:TIGR01257 1167 qsqrggcegtcsctskgfstrcparvdeitpEQVLDGDVNELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKqrAYASL 1246
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 16551961 806 FFKLEEAKHAFAIEEYSFSQATLEQVFVELTkeqeeEDNSCGTL 849
Cdd:TIGR01257 1247 FRELEETLADLGLSSFGISDTPLEEIFLKVT-----EDADSGSL 1285
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
511-714 |
5.50e-34 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 129.52 E-value: 5.50e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKKdfLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETS 590
Cdd:COG4133 1 MMLEAENLSCRRGERL--LFSG---------LSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDgSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDmkEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSM 670
Cdd:COG4133 70 RED-YRRRLAYLGHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 16551961 671 LGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTH 714
Cdd:COG4133 147 LSPAPLWLLDEPFTALDAAGVALLAELIA-AHLARGGAVLLTTH 189
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
513-741 |
1.31e-33 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 128.99 E-value: 1.31e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLlsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYssETSED 592
Cdd:COG1122 1 IELENLSFSYPGGTPAL----------DDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGK--DITKK 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DgsLKCM----GYCPQiNplwPD-----TTLQEhfEI-YGAV-KGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIK 661
Cdd:COG1122 69 N--LRELrrkvGLVFQ-N---PDdqlfaPTVEE--DVaFGPEnLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQK 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 662 RKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:COG1122 141 QRVAIAgvLAM--EPEVLVLDEPTAGLDPRGRRELLELLK-RLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
|
..
gi 16551961 740 VQ 741
Cdd:COG1122 218 PR 219
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
515-733 |
1.38e-33 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 128.35 E-value: 1.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKDFLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDG 594
Cdd:cd03225 2 LKNLSFSYPDGARPALDD---------ISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 SLKCMGYCPQiNplwPD-----TTLQEhfEI-YGAVK-GMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFA 667
Cdd:cd03225 73 LRRKVGLVFQ-N---PDdqffgPTVEE--EVaFGLENlGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIA 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 668 LSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:cd03225 147 GVLAMDPDILLLDEPTAGLDPAGRRELLELLKK-LKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
515-733 |
9.80e-33 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 123.89 E-value: 9.80e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKDFllsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDG 594
Cdd:cd00267 2 IENLSFRYGGRTAL-----------DNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 SLKCMGYCPQinplwpdttlqehfeiygavkgmsasdmkevisrithgldlkehlqktvkkLPAGIKRKLCFALSMLGNP 674
Cdd:cd00267 71 LRRRIGYVPQ---------------------------------------------------LSGGQRQRVALARALLLNP 99
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:cd00267 100 DLLLLDEPTSGLDPASRERLLELLR-ELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
517-738 |
4.02e-32 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 124.17 E-value: 4.02e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 517 NLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDDG 594
Cdd:cd03259 5 GLSKTYGSV-----------RALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDgrDVTGVPPERRN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 slkcMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNP 674
Cdd:cd03259 74 ----IGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03259 150 SLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
542-684 |
2.01e-29 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 114.28 E-value: 2.01e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIY 621
Cdd:pfam00005 4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENLRLG 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 622 GAVKGMSASDMKEVISRITHGLDL----KEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPST 684
Cdd:pfam00005 84 LLLKGLSKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
537-742 |
3.94e-29 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 116.38 E-value: 3.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLKcmgycP------------Q 604
Cdd:cd03219 14 VALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDG------EDITGLP-----PheiarlgigrtfQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 605 INPLWPDTTLQE-------HFEIYGAVKGMSASDMKEVISRITHGLD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNP 674
Cdd:cd03219 83 IPRLFPELTVLEnvmvaaqARTGSGLLLARARREEREARERAEELLErvgLADLADRPAGELSYGQQRRLEIARALATDP 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQH 742
Cdd:cd03219 163 KLLLLDEPAAGLNPEETEELAELIR-ELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDE 229
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
512-740 |
3.17e-28 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 114.02 E-value: 3.17e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEY-------DDKKDFLLSRKVKKVATKY----ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV 580
Cdd:COG1134 4 MIEVENVSKSYrlyhepsRSLKELLLRRRRTRREEFWalkdVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 581 flgdyssetsEDDGSlkcmgycpqINPLW-------PDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTV 653
Cdd:COG1134 84 ----------EVNGR---------VSALLelgagfhPELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 654 KKLPAGIKRKLCFALSMLGNPQITLLDEP-STGmDP----KAKQHMwrairTAFKNRKRAAILTTHYMEEAEAVCDRVAI 728
Cdd:COG1134 145 KTYSSGMRARLAFAVATAVDPDILLVDEVlAVG-DAafqkKCLARI-----RELRESGRTVIFVSHSMGAVRRLCDRAIW 218
|
250
....*....|..
gi 16551961 729 MVSGQLRCIGTV 740
Cdd:COG1134 219 LEKGRLVMDGDP 230
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
513-744 |
1.06e-27 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 112.21 E-value: 1.06e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETS 590
Cdd:cd03261 1 IELRGLTKSFGGR-----------TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDgeDISGLSE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDGSLKC-MGYCPQINPLWPDTT--------LQEHFEiygavkgMSASDMKEvisRITHGLDLKEhLQKTVKKLPA--- 658
Cdd:cd03261 70 AELYRLRRrMGMLFQSGALFDSLTvfenvafpLREHTR-------LSEEEIRE---IVLEKLEAVG-LRGAEDLYPAels 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 659 -GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:cd03261 139 gGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAE 218
|
....*..
gi 16551961 738 GTVQHLK 744
Cdd:cd03261 219 GTPEELR 225
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
513-738 |
1.21e-27 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 111.86 E-value: 1.21e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEY-------DDKKDFLLSRKVKKVATKY----ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVf 581
Cdd:cd03220 1 IELENVSKSYptykggsSSLKKLGILGRKGEVGEFWalkdVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 582 lgdyssETSEDDGSLKCMGYCPQinplwPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIK 661
Cdd:cd03220 80 ------TVRGRVSSLLGLGGGFN-----PELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMK 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 662 RKLCFALSMLGNPQITLLDEP-STGmDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03220 149 ARLAFAIATALEPDILLIDEVlAVG-DAAFQEKCQRRLR-ELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
513-733 |
1.94e-27 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 109.58 E-value: 1.94e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssETSED 592
Cdd:cd03229 1 LELKNVSKRYGQKT-----------VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDG---EDLTD 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGslkcmgycpqINPLWPDTTLQEHFEIYGAVKGMSasdmkeVISRITHGLDlkehlqktvkklpAGIKRKLCFALSMLG 672
Cdd:cd03229 67 LE----------DELPPLRRRIGMVFQDFALFPHLT------VLENIALGLS-------------GGQQQRVALARALAM 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 673 NPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:cd03229 118 DPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
515-739 |
3.82e-27 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 110.71 E-value: 3.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDdkkdfllsrkvKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDG 594
Cdd:cd03218 3 AENLSKRYG-----------KRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 -SLKCMGYCPQINPLWPDTTLQEHfeIYGAVKGMSASDmKEVISRITHGLDL--KEHLQKTV-KKLPAGIKRKLCFALSM 670
Cdd:cd03218 72 rARLGIGYLPQEASIFRKLTVEEN--ILAVLEIRGLSK-KEREEKLEELLEEfhITHLRKSKaSSLSGGERRRVEIARAL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 671 LGNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:cd03218 149 ATNPKFLLLDEPFAGVDPIAVQDIQKIIKI-LKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGT 216
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
515-734 |
7.35e-27 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 109.52 E-value: 7.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfllsRKVKKVatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSEDD 593
Cdd:cd03257 4 VKNLSVSFPTGG-----GSVKAL--DDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIiFDGKDLLKLSRRL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 594 GSL--KCMGYCPQ-----INPLWpdtTLQEHFE--IYGAVKGMSASDMKEVISRITHGLDLKEHLqktVKKLPA----GI 660
Cdd:cd03257 77 RKIrrKEIQMVFQdpmssLNPRM---TIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGLPEEV---LNRYPHelsgGQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 661 KRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03257 151 RQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
513-739 |
8.24e-27 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 109.63 E-value: 8.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsed 592
Cdd:cd03300 1 IELENVSKFYGGF-----------VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDG-------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 dgslKCMGYCP----QINPLWPDTTLQEHFEIYGAV------KGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKR 662
Cdd:cd03300 62 ----KDITNLPphkrPVNTVFQNYALFPHLTVFENIafglrlKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQ 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 663 KLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:cd03300 138 RVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
537-734 |
8.26e-27 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 110.13 E-value: 8.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLKcmgycP------------Q 604
Cdd:COG0411 18 VAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDG------RDITGLP-----PhriarlgiartfQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 605 INPLWPDTTLQEHFEI-------YGAVKGM-----SASDMKEVISRITHGLD---LKEHLQKTVKKLPAGIKRKLCFALS 669
Cdd:COG0411 87 NPRLFPELTVLENVLVaaharlgRGLLAALlrlprARREEREARERAEELLErvgLADRADEPAGNLSYGQQRRLEIARA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 670 MLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:COG0411 167 LATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV 231
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
512-743 |
1.14e-26 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 109.29 E-value: 1.14e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDdkkdfllSRKVkkvaTKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYssetse 591
Cdd:TIGR04406 1 TLVAENLIKSYK-------KRKV----VNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQ------ 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 dDGSLKCM--------GYCPQINPLWPDTTLQEHFEiygAVKGMSASDMKEVISRITHGLdLKEHLQKTVKKLPA----- 658
Cdd:TIGR04406 64 -DITHLPMherarlgiGYLPQEASIFRKLTVEENIM---AVLEIRKDLDRAEREERLEAL-LEEFQISHLRDNKAmslsg 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 659 GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:TIGR04406 139 GERRRVEIARALATNPKFILLDEPFAGVDPIAVGDIKKIIKH-LKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEG 217
|
....*
gi 16551961 739 TVQHL 743
Cdd:TIGR04406 218 TPAEI 222
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
511-742 |
5.58e-26 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 107.48 E-value: 5.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSEts 590
Cdd:COG1121 5 PAIELENLTVSYGGR-----------PVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPR-- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 eddGSLKCMGYCPQ---INPLWP----DTTLQEHFEIYGAVKGMSASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRK 663
Cdd:COG1121 72 ---RARRRIGYVPQraeVDWDFPitvrDVVLMGRYGRRGLFRRPSRAD-REAVDEALERVGLEDLADRPIGELSGGQQQR 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 664 LCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVaIMVSGQLRCIGTVQH 742
Cdd:COG1121 148 VLLARALAQDPDLLLLDEPFAGVDAATEEALYELLR-ELRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEE 224
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
530-741 |
7.78e-26 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 107.04 E-value: 7.78e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 530 LSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDDGslkcMGYCPQINP 607
Cdd:cd03299 6 LSKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNgkDITNLPPEKRD----ISYVPQNYA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 608 LWPDTTLQEHFEiYG-AVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGM 686
Cdd:cd03299 82 LFPHMTVYKNIA-YGlKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSAL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 687 DPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:cd03299 161 DVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPE 215
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
542-741 |
1.02e-25 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 107.05 E-value: 1.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSL------KCMGYCPQINPLWPDTTLQ 615
Cdd:COG1120 20 VSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDG------RDLASLsrrelaRRIAYVPQEPPAPFGLTVR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 E--------HFeiyGAVKGMSASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:COG1120 94 ElvalgrypHL---GLFGRPSAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTSHLD 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 16551961 688 PKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:COG1120 170 LAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
542-729 |
1.08e-25 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 105.69 E-value: 1.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSEtseddGSLKCMGYCPQ---INPLWPDT------ 612
Cdd:cd03235 18 VSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLE-----KERKRIGYVPQrrsIDRDFPISvrdvvl 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 613 -TLQEHfeiYGAVKGMSASDMKevisRITHGLD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:cd03235 93 mGLYGH---KGLFRRLSKADKA----KVDEALErvgLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDP 165
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 16551961 689 KAKQHMWRAIRTAfKNRKRAAILTTHYMEEAEAVCDRVAIM 729
Cdd:cd03235 166 KTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
513-729 |
1.11e-25 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 106.02 E-value: 1.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSE 591
Cdd:cd03293 1 LEVRNVSKTYGGGG-------GAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVlVDGEPVTGPGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DdgslkcMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:cd03293 74 D------RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALA 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIM 729
Cdd:cd03293 148 VDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
542-734 |
3.22e-25 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 104.26 E-value: 3.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEddgSLKCMGYCPQiNP---LWPDTTLQEhf 618
Cdd:cd03226 19 LSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKE---RRKSIGYVMQ-DVdyqLFTDSVREE-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGAvkgMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAI 698
Cdd:cd03226 93 LLLGL---KELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELI 169
|
170 180 190
....*....|....*....|....*....|....*.
gi 16551961 699 RTAfKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03226 170 REL-AAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
537-739 |
5.08e-25 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 102.12 E-value: 5.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssetsedDGSlkcmgycpqinplwpdttlqe 616
Cdd:cd03216 14 KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILV----------DGK--------------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 hfeiygAVKGMSASDMKEvisritHGLdlkehlqKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWR 696
Cdd:cd03216 63 ------EVSFASPRDARR------AGI-------AMVYQLSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFK 123
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 697 AIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGqlRCIGT 739
Cdd:cd03216 124 VIR-RLRAQGVAVIFISHRLDEVFEIADRVTVLRDG--RVVGT 163
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
533-745 |
7.52e-25 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 103.67 E-value: 7.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 533 KVKKVATKY--------ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLKC------ 598
Cdd:cd03224 2 EVENLNAGYgksqilfgVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDG------RDITGLPPherara 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 599 -MGYCPQINPLWPDTTLQEHFEI--YGAVKGMSASDMKEVISRIThglDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQ 675
Cdd:cd03224 76 gIGYVPEGRRIFPELTVEENLLLgaYARRRAKRKARLERVYELFP---RLKERRKQLAGTLSGGEQQMLAIARALMSRPK 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 676 ITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:cd03224 153 LLLLDEPSEGLAPKIVEEIFEAIRE-LRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
509-747 |
1.01e-24 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 106.72 E-value: 1.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 509 EKPSIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYS 586
Cdd:COG3842 2 AMPALELENVSKRYGDV-----------TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDgrDVT 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDDGslkcMGYCPQINPLWPDTTLQEHfeI-YG-AVKGMSASDMKEvisRITHGLD---LKEHLQKTVKKLPAG-- 659
Cdd:COG3842 71 GLPPEKRN----VGMVFQDYALFPHLTVAEN--VaFGlRMRGVPKAEIRA---RVAELLElvgLEGLADRYPHQLSGGqq 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 660 ----IKRklcfALSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:COG3842 142 qrvaLAR----ALAP--EPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIE 215
|
250
....*....|....*.
gi 16551961 736 CIGTVQHL----KSRF 747
Cdd:COG3842 216 QVGTPEEIyerpATRF 231
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
515-738 |
3.04e-24 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 100.59 E-value: 3.04e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKkdFLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-SETSEDD 593
Cdd:cd03214 2 VENLSVGYGGR--TVLDD---------LSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDlASLSPKE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 594 GSlKCMGYCPQInplwpdttlqehfeiygavkgmsasdMKEVisRITHgldLKEhlqKTVKKLPAGIKRKLCFALSMLGN 673
Cdd:cd03214 71 LA-RKIAYVPQA--------------------------LELL--GLAH---LAD---RPFNELSGGERQRVLLARALAQE 115
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 674 PQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03214 116 PPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
513-733 |
4.60e-24 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 99.76 E-value: 4.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYsSETSED 592
Cdd:cd03228 1 IEFKNVSFSYPGRPKPVL---------KDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV-DLRDLD 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSL-KCMGYCPQINPLWPDTtlqehfeiygavkgmsasdmkevisrithgldLKEHLqktvkkLPAGIKRKLCFALSML 671
Cdd:cd03228 71 LESLrKNIAYVPQDPFLFSGT--------------------------------IRENI------LSGGQRQRIAIARALL 112
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAvCDRVAIMVSGQ 733
Cdd:cd03228 113 RDPPILILDEATSALDPETEALILEALRALAKG--KTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
548-738 |
6.75e-24 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 100.45 E-value: 6.75e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 548 KGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysseTSEDDGSLKC--------MGYCPQINPLWPDTTLQEHFE 619
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNG----TVLFDSRKKInlppqqrkIGLVFQQYALFPHLNVRENLA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 iYGAvKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIR 699
Cdd:cd03297 98 -FGL-KRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELK 175
|
170 180 190
....*....|....*....|....*....|....*....
gi 16551961 700 TAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03297 176 QIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
511-743 |
1.61e-23 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 100.10 E-value: 1.61e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYddKKdfllsRKVkkvaTKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssets 590
Cdd:COG1137 2 MTLEAENLVKSY--GK-----RTV----VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDG------ 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDGSL-------KCMGYCPqinplwpdttlQEH--FeiygavKGMSASD--M---------KEVISRITHGLdLKE-HL 649
Cdd:COG1137 65 EDITHLpmhkrarLGIGYLP-----------QEAsiF------RKLTVEDniLavlelrklsKKEREERLEEL-LEEfGI 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 650 QKtVKKLPA-----GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAK---QHMwraIRTAfKNRKRAAILTTHYMEEAEA 721
Cdd:COG1137 127 TH-LRKSKAyslsgGERRRVEIARALATNPKFILLDEPFAGVDPIAVadiQKI---IRHL-KERGIGVLITDHNVRETLG 201
|
250 260
....*....|....*....|..
gi 16551961 722 VCDRVAIMVSGQLRCIGTVQHL 743
Cdd:COG1137 202 ICDRAYIISEGKVLAEGTPEEI 223
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
535-738 |
1.62e-23 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 99.64 E-value: 1.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDY---SSETSEDDGSLKCMGYCpqinpLWPD 611
Cdd:cd03301 12 NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRdvtDLPPKDRDIAMVFQNYA-----LYPH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 612 TTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAK 691
Cdd:cd03301 87 MTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 16551961 692 QHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03301 167 VQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
513-734 |
3.10e-23 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 98.72 E-value: 3.10e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDdkkdfllSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD----YSSE 588
Cdd:cd03255 1 IELKNLSKTYG-------GGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGtdisKLSE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 589 TSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFAL 668
Cdd:cd03255 74 KELAAFRRRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIAR 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 669 SMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAvCDRVAIMVSGQL 734
Cdd:cd03255 154 ALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
510-743 |
3.46e-23 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 104.21 E-value: 3.46e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 510 KPSIMVSNLHKEYDDKKDFLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPT---SGQVFLGDYS 586
Cdd:COG1123 2 TPLLEVRDLSVRYPGGDVPAV---------DGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDDGSLKCMGYCPQ-----INPLWPDTTLQEHFEIygavKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIK 661
Cdd:COG1123 73 LLELSEALRGRRIGMVFQdpmtqLNPVTVGDQIAEALEN----LGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 662 RKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:COG1123 149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228
|
..
gi 16551961 742 HL 743
Cdd:COG1123 229 EI 230
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
511-744 |
9.34e-23 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 98.13 E-value: 9.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDK---KDfllsrkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYS 586
Cdd:COG1127 4 PMIEVRNLTKSFGDRvvlDG--------------VSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEIlVDGQDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDDGS--LKCMGYCPQINPLWPDTT--------LQEHFeiygavkGMSASDMKEVISRITHGLDLKEHLqktvKKL 656
Cdd:COG1127 70 TGLSEKELYelRRRIGMLFQGGALFDSLTvfenvafpLREHT-------DLSEAEIRELVLEKLELVGLPGAA----DKM 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 657 PA----GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG 732
Cdd:COG1127 139 PSelsgGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADG 218
|
250
....*....|..
gi 16551961 733 QLRCIGTVQHLK 744
Cdd:COG1127 219 KIIAEGTPEELL 230
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
511-743 |
5.32e-22 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 100.99 E-value: 5.32e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKKdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-SET 589
Cdd:COG4988 335 PSIELEDVSFSYPGGR----------PALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDlSDL 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 SEDDGSlKCMGYCPQiNPLWPDTTLQEHF----------EIYGAVKgmsASDMKEVISRITHGLDlkehlqkTV-----K 654
Cdd:COG4988 405 DPASWR-RQIAWVPQ-NPYLFAGTIRENLrlgrpdasdeELEAALE---AAGLDEFVAALPDGLD-------TPlgeggR 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 655 KLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAvCDRVAIMVSGQL 734
Cdd:COG4988 473 GLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKG--RTVILITHRLALLAQ-ADRILVLDDGRI 549
|
....*....
gi 16551961 735 RCIGTVQHL 743
Cdd:COG4988 550 VEQGTHEEL 558
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
542-745 |
7.13e-22 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 95.43 E-value: 7.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLKC-------MGYCPQINPLWPDTTL 614
Cdd:COG0410 22 VSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDG------EDITGLPPhriarlgIGYVPEGRRIFPSLTV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHFEIyGAVKGMSASDMKEVISRIthgLD----LKEHLqktvkKLPAGikrklcfALS-----ML-------GNPQITL 678
Cdd:COG0410 96 EENLLL-GAYARRDRAEVRADLERV---YElfprLKERR-----RQRAG-------TLSggeqqMLaigralmSRPKLLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 679 LDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:COG0410 160 LDEPSLGLAPLIVEEIFEIIRR-LNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLA 225
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
481-753 |
2.12e-21 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 99.91 E-value: 2.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 481 PPDNEDEDEDVKAERLKvkelmgcqcceekPSIMVSNLHKEYDDKKDFLLSRkvkkvatkyISFCVKKGEILGLLGPNGA 560
Cdd:COG2274 455 PPEREEGRSKLSLPRLK-------------GDIELENVSFRYPGDSPPVLDN---------ISLTIKPGERVAIVGRSGS 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 561 GKSTIINILVGDIEPTSGQVFLGDYSSEtSEDDGSL-KCMGYCPQINPLW------------PDTTLQehfEIYGAVKgm 627
Cdd:COG2274 513 GKSTLLKLLLGLYEPTSGRILIDGIDLR-QIDPASLrRQIGVVLQDVFLFsgtirenitlgdPDATDE---EIIEAAR-- 586
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 628 sASDMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKR 707
Cdd:COG2274 587 -LAGLHDFIEALPMGYDTV--VGEGGSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTV 663
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 16551961 708 aaILTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSRFGKGYFL 753
Cdd:COG2274 664 --IIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
512-740 |
5.80e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 93.96 E-value: 5.80e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDKKDFllsrkvKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYssETSE 591
Cdd:PRK13637 2 SIKIENLTHIYMEGTPF------EKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGV--DITD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSL----KCMGYCPQinplWPDTTLqehFE-------IYGAVK-GMSASDMKEVISRITH--GLDLKEHLQKTVKKLP 657
Cdd:PRK13637 74 KKVKLsdirKKVGLVFQ----YPEYQL---FEetiekdiAFGPINlGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 658 AGIKRKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:PRK13637 147 GGQKRRVAIAgvVAM--EPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCE 224
|
....*
gi 16551961 736 CIGTV 740
Cdd:PRK13637 225 LQGTP 229
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
512-747 |
6.17e-21 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 95.21 E-value: 6.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDkkdFLLSRKVkkvatkyiSFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD---YSSE 588
Cdd:COG1118 2 SIEVRNISKRFGS---FTLLDDV--------SLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGrdlFTNL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 589 TSEDDGslkcMGYCPQiNP-LWPDTTLQEHfeI-YGA-VKGMSASDMKEvisRITHGLDLKeHLQKTVKKLPAgikrklc 665
Cdd:COG1118 71 PPRERR----VGFVFQ-HYaLFPHMTVAEN--IaFGLrVRPPSKAEIRA---RVEELLELV-QLEGLADRYPS------- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 666 fALS-----------ML-GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:COG1118 133 -QLSggqrqrvalarALaVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGR 211
|
250
....*....|....*...
gi 16551961 734 LRCIGTVQHL----KSRF 747
Cdd:COG1118 212 IEQVGTPDEVydrpATPF 229
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
542-733 |
8.99e-21 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 92.45 E-value: 8.99e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVF--LG-DYSSETSEDdgsLKC-MGYCpqinplwpDTTLQEH 617
Cdd:COG1119 22 ISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrlFGeRRGGEDVWE---LRKrIGLV--------SPALQLR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FEiygavKGMSASDMkeVIS---------------------RITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQI 676
Cdd:COG1119 91 FP-----RDETVLDV--VLSgffdsiglyreptdeqrerarELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPEL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 677 TLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:COG1119 164 LILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
509-738 |
9.26e-21 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 96.80 E-value: 9.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 509 EKPSIMVSNLHKEYddkkdFLLSRKVKKvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVF--LGDYS 586
Cdd:TIGR03269 276 GEPIIKVRNVSKRY-----ISVDRGVVK-AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrVGDEW 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDDGSLK-----CMGYCPQINPLWPDTTLQEHF-EIYGAVKGMSASDMKEVISRITHGLD---LKEHLQKTVKKLP 657
Cdd:TIGR03269 350 VDMTKPGPDGRgrakrYIGILHQEYDLYPHRTVLDNLtEAIGLELPDELARMKAVITLKMVGFDeekAEEILDKYPDELS 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 658 AGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:TIGR03269 430 EGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKI 509
|
.
gi 16551961 738 G 738
Cdd:TIGR03269 510 G 510
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
542-734 |
5.15e-20 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 88.76 E-value: 5.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVG--DIEPTSGQVFLGDYSSetseDDGSLKC-MGYCPQINPLWPDTTLQEHF 618
Cdd:cd03213 28 VSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPL----DKRSFRKiIGYVPQDDILHPTLTVRETL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGAVKGMSasdmkevisrithgldlkehlqktvkklpAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAI 698
Cdd:cd03213 104 MFAAKLRGLS-----------------------------GGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLL 154
|
170 180 190
....*....|....*....|....*....|....*..
gi 16551961 699 RtAFKNRKRAAILTTHY-MEEAEAVCDRVAIMVSGQL 734
Cdd:cd03213 155 R-RLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
512-739 |
7.68e-20 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 89.71 E-value: 7.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDkkdFllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSET 589
Cdd:cd03296 2 SIEVRNVSKRFGD---F--------VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGgeDATDVP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 SEDDGslkcMGYCPQINPLWPDTTLQEH----FEIYGAVKGMSASDMKEVISRIthgLDLKeHLQKTVKKLPA----GIK 661
Cdd:cd03296 71 VQERN----VGFVFQHYALFRHMTVFDNvafgLRVKPRSERPPEAEIRAKVHEL---LKLV-QLDWLADRYPAqlsgGQR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 662 RKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:cd03296 143 QRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
518-739 |
9.90e-20 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 90.01 E-value: 9.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 518 LHKEYDDKKDfLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSEDDGSL- 596
Cdd:cd03294 20 LLAKGKSKEE-ILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLI-DGQDIAAMSRKELr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 597 ----KCMGYCPQINPLWPDTTLQEHFEiYG-AVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:cd03294 98 elrrKKISMVFQSFALLPHRTVLENVA-FGlEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALA 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:cd03294 177 VDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGT 244
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
513-743 |
1.29e-19 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 88.39 E-value: 1.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINIL-----VGDIEPTSGQVFL-GDYS 586
Cdd:cd03260 1 IELRDLNVYYGDKH-----------ALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlndLIPGAPDEGEVLLdGKDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDDGSLKC-MGYCPQI-NPLwpDTTLQEHFEiYGA----VKGMSASD--MKEVISRIthGLDLKEHLQKTVKKLPA 658
Cdd:cd03260 70 YDLDVDVLELRRrVGMVFQKpNPF--PGSIYDNVA-YGLrlhgIKLKEELDerVEEALRKA--ALWDEVKDRLHALGLSG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 659 GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfkNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:cd03260 145 GQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFG 222
|
....*
gi 16551961 739 TVQHL 743
Cdd:cd03260 223 PTEQI 227
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
508-743 |
1.37e-19 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 93.04 E-value: 1.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 508 EEKPSIMVSNLHKEYDdkkdflLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DY 585
Cdd:COG1123 256 AAEPLLEVRNLSKRYP------VRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDgkDL 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 586 SSETSEDDGSL-KCMGYCPQ-----INPLWP-DTTLQEHFEIYGavkGMSASDMKEVISRI--THGLDlKEHLQKTVKKL 656
Cdd:COG1123 330 TKLSRRSLRELrRRVQMVFQdpyssLNPRMTvGDIIAEPLRLHG---LLSRAERRERVAELleRVGLP-PDLADRYPHEL 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 657 PAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRC 736
Cdd:COG1123 406 SGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVE 485
|
....*..
gi 16551961 737 IGTVQHL 743
Cdd:COG1123 486 DGPTEEV 492
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
531-743 |
1.56e-19 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 88.90 E-value: 1.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 531 SRKVKKVATKYISFCVKKGEILGLLGPNGAGKST---IINILvgdIEPTSGQVFLGDysSETSEDDGS--LKCMGYCPQI 605
Cdd:cd03295 9 RYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTtmkMINRL---IEPTSGEIFIDG--EDIREQDPVelRRKIGYVIQQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 NPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITH--GLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPS 683
Cdd:cd03295 84 IGLFPHMTVEENIALVPKLLKWPKEKIRERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPF 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 684 TGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:cd03295 164 GALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEI 223
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
537-748 |
1.66e-19 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 94.04 E-value: 1.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-------GDYSSEtseddgslKCMGYCPQINPLW 609
Cdd:NF033858 280 TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLfgqpvdaGDIATR--------RRVGYMSQAFSLY 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 610 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK 689
Cdd:NF033858 352 GELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPV 431
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 690 AKQHMWRAI----RtafknRKRAAI-LTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSRFG 748
Cdd:NF033858 432 ARDMFWRLLielsR-----EDGVTIfISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAARG 489
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
542-729 |
1.97e-19 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 92.73 E-value: 1.97e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQiNPLWPDTTLQEhfEIY 621
Cdd:TIGR02857 341 VSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQ-HPFLFAGTIAE--NIR 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDMKEVISRIthGLD-----LKEHLQKTVKK----LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQ 692
Cdd:TIGR02857 418 LARPDASDAEIREALERA--GLDefvaaLPQGLDTPIGEggagLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEA 495
|
170 180 190
....*....|....*....|....*....|....*..
gi 16551961 693 HMWRAIRTAFKNrkRAAILTTHYMEEAEAvCDRVAIM 729
Cdd:TIGR02857 496 EVLEALRALAQG--RTVLLVTHRLALAAL-ADRIVVL 529
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
513-743 |
4.14e-19 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 87.25 E-value: 4.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDkkdfllsRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSED 592
Cdd:cd03258 2 IELKNVSKVFGD-------TGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLV-DGTDLTLLS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSL----KCMGYCPQ-INPLWPDTTLQE---HFEIYGavkgmsaSDMKEVISRITHGL---DLKEHLQKTVKKLPAGIK 661
Cdd:cd03258 74 GKELrkarRRIGMIFQhFNLLSSRTVFENvalPLEIAG-------VPKAEIEERVLELLelvGLEDKADAYPAQLSGGQK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 662 RKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:cd03258 147 QRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVE 226
|
..
gi 16551961 742 HL 743
Cdd:cd03258 227 EV 228
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
510-735 |
8.60e-19 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 90.89 E-value: 8.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 510 KPSIMVSNLHKEYDDKKdfLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysset 589
Cdd:COG0488 313 KKVLELEGLSKSYGDKT--LLDD---------LSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGE----- 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 seddgSLKcMGYCPQIN-PLWPDTTLQEHFEIYgavkgmsASDMKEVISRithGLdLK------EHLQKTVKKLPAGIKR 662
Cdd:COG0488 377 -----TVK-IGYFDQHQeELDPDKTVLDELRDG-------APGGTEQEVR---GY-LGrflfsgDDAFKPVGVLSGGEKA 439
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 663 KLCFALSMLGNPQITLLDEPSTGMDPKAKQhmwrAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:COG0488 440 RLALAKLLLSPPNVLLLDEPTNHLDIETLE----ALEEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVR 508
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
537-740 |
1.30e-18 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 90.09 E-value: 1.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssetsedDG---SLKcmgycpqiNP------ 607
Cdd:COG3845 19 VANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILI----------DGkpvRIR--------SPrdaial 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 608 ----------LWPDTTLQEHFeIYGAVKGMSAS-DMKEVISRI-----THGLDLkeHLQKTVKKLPAGIKRKL----Cfa 667
Cdd:COG3845 81 gigmvhqhfmLVPNLTVAENI-VLGLEPTKGGRlDRKAARARIrelseRYGLDV--DPDAKVEDLSVGEQQRVeilkA-- 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 668 lsMLGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLrcIGTV 740
Cdd:COG3845 156 --LYRGARILILDEPTAVLTPQEADELFEILR-RLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV--VGTV 223
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
542-734 |
1.40e-18 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 83.80 E-value: 1.40e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDDGslKCMGYCPQINPLWPDTtlqehfe 619
Cdd:cd03246 21 VSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDgaDISQWDPNELG--DHVGYLPQDDELFSGS------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 iygavkgmsasdMKEVIsrithgldlkehlqktvkkLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIR 699
Cdd:cd03246 92 ------------IAENI-------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIA 140
|
170 180 190
....*....|....*....|....*....|....*
gi 16551961 700 tAFKNRKRAAILTTHYMEEAEAvCDRVAIMVSGQL 734
Cdd:cd03246 141 -ALKAAGATRIVIAHRPETLAS-ADRILVLEDGRV 173
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
542-739 |
4.02e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 88.54 E-value: 4.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-----YSSETSEDDGslkcMGYCPQ-INpLWPDTTLQ 615
Cdd:COG1129 23 VSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGepvrfRSPRDAQAAG----IAIIHQeLN-LVPNLSVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 E----HFEI--YGAVkgmsasDMKEVISR---ITHGLDLKEHLQKTVKKLPAGiKRKL---CFALSMlgNPQITLLDEPS 683
Cdd:COG1129 98 EniflGREPrrGGLI------DWRAMRRRareLLARLGLDIDPDTPVGDLSVA-QQQLveiARALSR--DARVLILDEPT 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 684 TGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLrcIGT 739
Cdd:COG1129 169 ASLTEREVERLFRIIRR-LKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL--VGT 221
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
511-747 |
4.55e-18 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 87.20 E-value: 4.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSET 589
Cdd:PRK11607 18 PLLEIRNLTKSFDGQH-----------AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLdGVDLSHV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 SEDDGSLKCMGycpQINPLWPDTTLQEHFEiYGAVKGMSASDmkEVISRITHGLDLKeHLQKTVKKLP----AGIKRKLC 665
Cdd:PRK11607 87 PPYQRPINMMF---QSYALFPHMTVEQNIA-FGLKQDKLPKA--EIASRVNEMLGLV-HMQEFAKRKPhqlsGGQRQRVA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 666 FALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT----VQ 741
Cdd:PRK11607 160 LARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEpeeiYE 239
|
....*.
gi 16551961 742 HLKSRF 747
Cdd:PRK11607 240 HPTTRY 245
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
513-734 |
6.00e-18 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 82.36 E-value: 6.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysSETSED 592
Cdd:cd03247 1 LSINNVSFSYPEQE---------QQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDG--VPVSDL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSL-KCMGYCPQiNPLWPDTTLQEHFEiygavkgmsasdmkevisrithgldlkehlqktvKKLPAGIKRKLCFALSML 671
Cdd:cd03247 70 EKALsSLISVLNQ-RPYLFDTTLRNNLG----------------------------------RRFSGGERQRLALARILL 114
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAVcDRVAIMVSGQL 734
Cdd:cd03247 115 QDAPIVLLDEPTVGLDPITERQLLSLIFEVLKD--KTLIWITHHLTGIEHM-DKILFLENGKI 174
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
513-746 |
8.24e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 84.40 E-value: 8.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDfllsrkvkKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSE 591
Cdd:PRK13650 5 IEVKNLTFKYKEDQE--------KYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIdGDLLTEENV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKcMGYCPQiNP--LWPDTTLQEHFEIYGAVKGMSASDMKEvisRITHGLDL---KEHLQKTVKKLPAGIKRKLCF 666
Cdd:PRK13650 77 WDIRHK-IGMVFQ-NPdnQFVGATVEDDVAFGLENKGIPHEEMKE---RVNEALELvgmQDFKEREPARLSGGQKQRVAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 667 ALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQHLKSR 746
Cdd:PRK13650 152 AGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSR 230
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
513-733 |
1.29e-17 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 83.00 E-value: 1.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLlsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSeTSED 592
Cdd:cd03256 1 IEVENLSKTYPNGKKAL----------KDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDI-NKLK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKcmGYCPQINPLWPDTTLQEHFEIYGAV-----------KGMSASDMKEVISRITHGLD---LKEHLQKTVKKLPA 658
Cdd:cd03256 70 GKALR--QLRRQIGMIFQQFNLIERLSVLENVlsgrlgrrstwRSLFGLFPKEEKQRALAALErvgLLDKAYQRADQLSG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 659 GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:cd03256 148 GQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
615-842 |
1.40e-17 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 85.17 E-value: 1.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHM 694
Cdd:NF000106 104 RENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEV 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 695 WRAIRTAFKNrKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGkGYFLEIKLKdwiENLEVDRLQREI- 773
Cdd:NF000106 184 WDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQIRPA---HAAELDRMVGAIa 258
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 774 QYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEakHAFAIEEYSFSQATLEQVFVELTKEQEEE 842
Cdd:NF000106 259 QAGLDGIAGATADHEDGVVNVPIVSDEQLSAVVGMLGE--RGFTISGHQHPSAQL*EVFLAITGQKTSE 325
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
513-705 |
2.21e-17 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 82.27 E-value: 2.21e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLlsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSED 592
Cdd:cd03254 3 IEFENVNFSYDEKKPVL----------KDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWPDTTLqEHFEIygavkGMSASDMKEVI--SRITHGLDLKEHLQK---TV-----KKLPAGIKR 662
Cdd:cd03254 73 KSLRSMIGVVLQDTFLFSGTIM-ENIRL-----GRPNATDEEVIeaAKEAGAHDFIMKLPNgydTVlgengGNLSQGERQ 146
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 663 KLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNR 705
Cdd:cd03254 147 LLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGR 189
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
533-739 |
2.35e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 83.12 E-value: 2.35e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 533 KVKKVATKY----------ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDdgSLKCMG 600
Cdd:PRK13632 9 KVENVSFSYpnsennalknVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDgiTISKENLKE--IRKKIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 601 YCPQiNPlwpD-----TTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQ 675
Cdd:PRK13632 87 IIFQ-NP---DnqfigATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPE 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 676 ITLLDEpSTGM-DPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAeAVCDRVAIMVSGQLRCIGT 739
Cdd:PRK13632 163 IIIFDE-STSMlDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGK 225
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
542-739 |
2.56e-17 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 82.25 E-value: 2.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetseDDGSL--------KCMGYCPQinplwpDTT 613
Cdd:PRK10895 22 VSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDD-------EDISLlplhararRGIGYLPQ------EAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 LQEHFEIYGAVkgMSASDMKEVISRITHGLDLKE--------HLQKTV-KKLPAGIKRKLCFALSMLGNPQITLLDEPST 684
Cdd:PRK10895 89 IFRRLSVYDNL--MAVLQIRDDLSAEQREDRANElmeefhieHLRDSMgQSLSGGERRRVEIARALAANPKFILLDEPFA 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 685 GMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:PRK10895 167 GVDPISVIDIKRIIE-HLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
515-739 |
3.78e-17 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 84.70 E-value: 3.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDD-------------KKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVF 581
Cdd:PRK10070 7 IKNLYKIFGEhpqrafkyieqglSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 582 LGDYS----SETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLP 657
Cdd:PRK10070 87 IDGVDiakiSDAELREVRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 658 AGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:PRK10070 167 GGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQV 246
|
..
gi 16551961 738 GT 739
Cdd:PRK10070 247 GT 248
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
538-743 |
5.28e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 82.20 E-value: 5.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG----DYSSEtseddGSLKC-----MGYCPQINPL 608
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDgkpiDYSRK-----GLMKLresvgMVFQDPDNQL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 609 WPDTTLQEhfEIYGAVKGMSASDmkEVISRITHGLDLK--EHLQ-KTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTG 685
Cdd:PRK13636 96 FSASVYQD--VSFGAVNLKLPED--EVRKRVDNALKRTgiEHLKdKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAG 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 686 MDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:PRK13636 172 LDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
535-734 |
5.95e-17 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 80.71 E-value: 5.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQinplwpDTTL 614
Cdd:cd03245 16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQ------DVTL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 qehfeIYGAVK-----GMSASDMKEVISRIT------------HGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQIT 677
Cdd:cd03245 90 -----FYGTLRdnitlGAPLADDERILRAAElagvtdfvnkhpNGLDLQ--IGERGRGLSGGQRQAVALARALLNDPPIL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 678 LLDEPSTGMDPKAKQHMWRAIRTAFknRKRAAILTTHYMeEAEAVCDRVAIMVSGQL 734
Cdd:cd03245 163 LLDEPTSAMDMNSEERLKERLRQLL--GDKTLIIITHRP-SLLDLVDRIIVMDSGRI 216
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
515-682 |
6.43e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 84.73 E-value: 6.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssetsedDG 594
Cdd:COG0488 1 LENLSKSFGGRP--LLDD---------VSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI----------PK 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 SLKcMGYCPQINPLWPDTTLQE-----HFEIYGAVK---------GMSASDMKEV------------------ISRITHG 642
Cdd:COG0488 60 GLR-IGYLPQEPPLDDDLTVLDtvldgDAELRALEAeleeleaklAEPDEDLERLaelqeefealggweaearAEEILSG 138
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 16551961 643 LDLKEH-LQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEP 682
Cdd:COG0488 139 LGFPEEdLDRPVSELSGGWRRRVALARALLSEPDLLLLDEP 179
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
542-714 |
7.19e-17 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 79.92 E-value: 7.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSlkcMGYCPQINPLWPDTTLQEHFEIY 621
Cdd:PRK13539 21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEA---CHYLGHRNAMKPALTVAENLEFW 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDMKEVISRIthGLDLKEHLQktVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTa 701
Cdd:PRK13539 98 AAFLGGEELDIAAALEAV--GLAPLAHLP--FGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRA- 172
|
170
....*....|....*
gi 16551961 702 fkNRKR--AAILTTH 714
Cdd:PRK13539 173 --HLAQggIVIAATH 185
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
542-687 |
7.45e-17 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 81.31 E-value: 7.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssetsEDDGSLKcMGYCPQinPLWPDTTLQEHFEIY 621
Cdd:PRK09544 23 VSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI----------KRNGKLR-IGYVPQ--KLYLDTTLPLTVNRF 89
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 622 GAVK-GMSASDMKEVISRITHGldlkeHL-QKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK09544 90 LRLRpGTKKEDILPALKRVQAG-----HLiDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
538-741 |
8.28e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 84.45 E-value: 8.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDDGSLKcMGYCPQINPLWPDTTLQ 615
Cdd:PRK09700 20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINniNYNKLDHKLAAQLG-IGIIYQELSVIDELTVL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEI----YGAVKGMSASD---MKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:PRK09700 99 ENLYIgrhlTKKVCGVNIIDwreMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTN 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 16551961 689 KAKQHMWrAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:PRK09700 179 KEVDYLF-LIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVS 230
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
513-747 |
1.33e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 83.70 E-value: 1.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVG--DIEPTSGQVFlgdYSSETS 590
Cdd:TIGR03269 1 IEVKNLTKKFDGKE-----------VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRII---YHVALC 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EDDGSL-----------KCMG-YCPQINPLW-PDTT------------LQEHFEIYG---------------------AV 624
Cdd:TIGR03269 67 EKCGYVerpskvgepcpVCGGtLEPEEVDFWnLSDKlrrrirkriaimLQRTFALYGddtvldnvlealeeigyegkeAV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 -KGMSASDMKEVISRITHgldlkehlqkTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFK 703
Cdd:TIGR03269 147 gRAVDLIEMVQLSHRITH----------IARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVK 216
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 16551961 704 NRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRF 747
Cdd:TIGR03269 217 ASGISMVLTSHWPEVIEDLSDKAIWLENGEIKEEGTPDEVVAVF 260
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
513-739 |
2.39e-16 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 79.20 E-value: 2.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLlsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETS 590
Cdd:cd03253 1 IEFENVTFAYDPGRPVL----------KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDgqDIREVTL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 591 EddgSL-KCMGYCPQINPLWPDTTL-----------QEhfEIYGAVKgmsASDMKEVISRITHGLDlkehlqkTV----- 653
Cdd:cd03253 71 D---SLrRAIGVVPQDTVLFNDTIGynirygrpdatDE--EVIEAAK---AAQIHDKIMRFPDGYD-------TIvgerg 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 654 KKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAeAVCDRVAIMVSGQ 733
Cdd:cd03253 136 LKLSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLSTI-VNADKIIVLKDGR 212
|
....*.
gi 16551961 734 LRCIGT 739
Cdd:cd03253 213 IVERGT 218
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
508-714 |
2.43e-16 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 83.18 E-value: 2.43e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 508 EEKPSIMVSNLHKEYDDKKDFLlsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSS 587
Cdd:TIGR02868 330 LGKPTLELRDLSAGYPGAPPVL----------DGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPV 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 588 ETSEDDGSLKCMGYCPQiNPLWPDTTLQEHFEIygAVKGMSASDMKEVISRI---------THGLDLKehLQKTVKKLPA 658
Cdd:TIGR02868 400 SSLDQDEVRRRVSVCAQ-DAHLFDTTVRENLRL--ARPDATDEELWAALERVgladwlralPDGLDTV--LGEGGARLSG 474
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 659 GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfkNRKRAAILTTH 714
Cdd:TIGR02868 475 GERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAA--LSGRTVVLITH 528
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
524-747 |
3.80e-16 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 80.92 E-value: 3.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 524 DKKDFLLSRKVKK-----VATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdysseTSED--DGSL 596
Cdd:PRK11432 2 TQKNFVVLKNITKrfgsnTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFI------DGEDvtHRSI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 597 K----CMGYcpQINPLWPDTTLQEHFEiYG-AVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:PRK11432 76 QqrdiCMVF--QSYALFPHMSLGENVG-YGlKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL----KSRF 747
Cdd:PRK11432 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELyrqpASRF 232
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
509-743 |
5.44e-16 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 79.29 E-value: 5.44e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 509 EKPSIMVSNLHKEYDDKKDFllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDY--S 586
Cdd:PRK13635 2 KEEIIRVEHISFRYPDAATY---------ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMvlS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 SETSEDdgSLKCMGYCPQiNplwPD-----TTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIK 661
Cdd:PRK13635 73 EETVWD--VRRQVGMVFQ-N---PDnqfvgATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 662 RKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILT-THYMEEAeAVCDRVAIMVSGQLRCIGTV 740
Cdd:PRK13635 147 QRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQ-LKEQKGITVLSiTHDLDEA-AQADRVIVMNKGEILEEGTP 224
|
...
gi 16551961 741 QHL 743
Cdd:PRK13635 225 EEI 227
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
512-747 |
5.51e-16 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 80.50 E-value: 5.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDY---SSE 588
Cdd:COG3839 3 SLELENVSKSYGGV-----------EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRdvtDLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 589 TSEDDgslkcMGYCPQiNP-LWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAG-------- 659
Cdd:COG3839 72 PKDRN-----IAMVFQ-SYaLYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGqrqrvalg 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 660 --IKRklcfalsmlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:COG3839 146 raLVR----------EPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQV 215
|
250
....*....|....
gi 16551961 738 GTVQHL----KSRF 747
Cdd:COG3839 216 GTPEELydrpANLF 229
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
512-738 |
5.73e-16 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 78.70 E-value: 5.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEY-------DDKKDFLLSRKVKKV--ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVfl 582
Cdd:PRK13546 4 SVNIKNVTKEYriyrtnkERMKDALIPKHKNKTffALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV-- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 583 gdyssetsEDDGSLKCMGYCPQINplwPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKR 662
Cdd:PRK13546 82 --------DRNGEVSVIAISAGLS---GQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 663 KLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:PRK13546 151 KLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIY-EFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYG 225
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
513-791 |
6.04e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 79.28 E-value: 6.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLLSrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-----S 587
Cdd:PRK13645 7 IILDNVSYTYAKKTPFEFK------ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAipanlK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 588 ETSEDDGSLKCMGYCPQinplWPDTTL-QEHFE---IYGAVKgmSASDMKEVISRITHGLDL----KEHLQKTVKKLPAG 659
Cdd:PRK13645 81 KIKEVKRLRKEIGLVFQ----FPEYQLfQETIEkdiAFGPVN--LGENKQEAYKKVPELLKLvqlpEDYVKRSPFELSGG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 660 IKRKLCFA--LSMLGNPQItlLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:PRK13645 155 QKRRVALAgiIAMDGNTLV--LDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISI 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 738 GTV------QHLKSRFG----KGYFLEIKLKdwieNLEVDRLQREIQYIfpnasrqESFSSILA 791
Cdd:PRK13645 233 GSPfeifsnQELLTKIEidppKLYQLMYKLK----NKGIDLLNKNIRTI-------EEFAKELA 285
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
540-739 |
6.07e-16 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 77.53 E-value: 6.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-SETSEDDgsL-KCMGYCPQINPLWPDTT---- 613
Cdd:cd03244 21 KNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDiSKIGLHD--LrSRISIIPQDPVLFSGTIrsnl 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 --LQEH--FEIYGAVKGMSasdMKEVISRITHGLDLKEHLQKtvKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK 689
Cdd:cd03244 99 dpFGEYsdEELWQALERVG---LKEFVESLPGGLDTVVEEGG--ENLSVGQRQLLCLARALLRKSKILVLDEATASVDPE 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 16551961 690 AKQHMWRAIRTAFKNRkraAILT-THYMeeaEAV--CDRVAIMVSGQLRCIGT 739
Cdd:cd03244 174 TDALIQKTIREAFKDC---TVLTiAHRL---DTIidSDRILVLDKGRVVEFDS 220
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
542-739 |
9.37e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 78.62 E-value: 9.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDY----SSETSEDDGSLKCMGYCPQI--NPLWPDTTLQ 615
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIvvssTSKQKEIKPVRKKVGVVFQFpeSQLFEETVLK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EhfEIYGAVK-GMSASDMKEVISRITHGLDL-KEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQH 693
Cdd:PRK13643 105 D--VAFGPQNfGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIE 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16551961 694 MWRAIRTAFKNrKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:PRK13643 183 MMQLFESIHQS-GQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
513-726 |
1.15e-15 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 74.79 E-value: 1.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSetsed 592
Cdd:cd03221 1 IELENLSKTYGGKL--LLKD---------ISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVK----- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 dgslkcMGYCPQinplwpdttlqehfeiygavkgmsasdmkevisrithgldlkehlqktvkkLPAGIKRKLCFALSMLG 672
Cdd:cd03221 65 ------IGYFEQ---------------------------------------------------LSGGEKMRLALAKLLLE 87
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 16551961 673 NPQITLLDEPSTGMDPKAKQhmwrAIRTAFKNRKRAAILTTHYMEEAEAVCDRV 726
Cdd:cd03221 88 NPNLLLLDEPTNHLDLESIE----ALEEALKEYPGTVILVSHDRYFLDQVATKI 137
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
542-734 |
1.23e-15 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 75.93 E-value: 1.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-----YSSETSEDDGslkcMGYCPqinplwpdttlQE 616
Cdd:cd03215 19 VSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGkpvtrRSPRDAIRAG----IAYVP-----------ED 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEiYGAVKGMSasdmkevisrITHGLDLKEHL-----QktvkklpagikrKLCFALSMLGNPQITLLDEPSTGMDPKAK 691
Cdd:cd03215 84 RKR-EGLVLDLS----------VAENIALSSLLsggnqQ------------KVVLARWLARDPRVLILDEPTRGVDVGAK 140
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 692 QHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03215 141 AEIYRLIR-ELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
546-730 |
1.55e-15 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 80.60 E-value: 1.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssetsedDGSLKcMGYCPQ-INPLWpDTTLQEHfeIYGAV 624
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV------------DEDLK-ISYKPQyISPDY-DGTVEEF--LRSAN 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 KGMSASDMKEviSRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKN 704
Cdd:COG1245 427 TDDFGSSYYK--TEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAEN 504
|
170 180
....*....|....*....|....*...
gi 16551961 705 RKRAAILTTH--YMeeAEAVCDRvaIMV 730
Cdd:COG1245 505 RGKTAMVVDHdiYL--IDYISDR--LMV 528
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
515-751 |
1.71e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 76.03 E-value: 1.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVG--DIEPTSGQVFLGDYS-SETSE 591
Cdd:cd03217 3 IKDLHVSVGGKE--IL---------KGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKGEDiTDLPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKCMGYCPQINPlwpdttlqehfEIygavkgmsasdmkevisritHGLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:cd03217 72 EERARLGIFLAFQYPP-----------EI--------------------PGVKNADFLRYVNEGFSGGEKKRNEILQLLL 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAV-CDRVAIMVSGQLRCIGTVQHLKSRFGKG 750
Cdd:cd03217 121 LEPDLAILDEPDSGLDIDALRLVAEVINK-LREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGDKELALEIEKKG 199
|
.
gi 16551961 751 Y 751
Cdd:cd03217 200 Y 200
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
542-739 |
2.43e-15 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 80.21 E-value: 2.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG-----DYSSEtseddgSL-KCMGYCPQINPLW------ 609
Cdd:COG1132 359 ISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDgvdirDLTLE------SLrRQIGVVPQDTFLFsgtire 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 610 ------PDTTLQEhfeIYGAVKgmsASDMKEVISRITHGLDlkehlqkTV-----KKLPAGIKRKLCFALSMLGNPQITL 678
Cdd:COG1132 433 nirygrPDATDEE---VEEAAK---AAQAHEFIEALPDGYD-------TVvgergVNLSGGQRQRIAIARALLKDPPILI 499
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 679 LDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAvCDRVAIMVSGQLRCIGT 739
Cdd:COG1132 500 LDEATSALDTETEALIQEALERLMKG--RTTIVIAHRLSTIRN-ADRILVLDDGRIVEQGT 557
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
536-774 |
2.66e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 77.37 E-value: 2.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 536 KVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCM----GYCPQI--NPLW 609
Cdd:PRK13634 20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKKLKPLrkkvGIVFQFpeHQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 610 PDTTLQEhfeI-YGAVK-GMSASD----MKEVISRIthGLDlKEHLQKTVKKLPAGIKRKLCFA--LSMlgNPQITLLDE 681
Cdd:PRK13634 100 EETVEKD---IcFGPMNfGVSEEDakqkAREMIELV--GLP-EELLARSPFELSGGQMRRVAIAgvLAM--EPEVLVLDE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 682 PSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLksrFGKGyfleiklkDWI 761
Cdd:PRK13634 172 PTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI---FADP--------DEL 240
|
250
....*....|....*...
gi 16551961 762 ENLEVD-----RLQREIQ 774
Cdd:PRK13634 241 EAIGLDlpetvKFKRALE 258
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
542-734 |
2.78e-15 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 75.77 E-value: 2.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEP---TSGQVFlgdYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHF 618
Cdd:cd03234 26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQIL---FNGQPRKPDQFQKCVAYVRQDDILLPGLTVRETL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIY----------GAVKGMSASD--MKEV-ISRITHGLdlkehlqktVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTG 685
Cdd:cd03234 103 TYTailrlprkssDAIRKKRVEDvlLRDLaLTRIGGNL---------VKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 686 MDPkakqhmwraiRTAFK---------NRKRAAILTTHY-MEEAEAVCDRVAIMVSGQL 734
Cdd:cd03234 174 LDS----------FTALNlvstlsqlaRRNRIVILTIHQpRSDLFRLFDRILLLSSGEI 222
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
535-793 |
2.84e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 77.13 E-value: 2.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSL----KCMGYCPQInplwP 610
Cdd:PRK13646 19 EHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIrpvrKRIGMVFQF----P 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 611 DTTLQE---HFEIYGAVK--GMSASDMKEVISRITHGLDL-KEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPST 684
Cdd:PRK13646 95 ESQLFEdtvEREIIFGPKnfKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 685 GMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLksrFGKGYfleiKLKDW-IEN 763
Cdd:PRK13646 175 GLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL---FKDKK----KLADWhIGL 247
|
250 260 270
....*....|....*....|....*....|....*
gi 16551961 764 LEVDRLQREI----QYIFPN-ASRQESFSSIlaYK 793
Cdd:PRK13646 248 PEIVQLQYDFeqkyQTKLKDiALTEEEFVSL--YK 280
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
512-739 |
4.27e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 77.20 E-value: 4.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDKKDFLLsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSE 591
Cdd:PRK13631 21 ILRVKNLYCVFDEKQENEL------VALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKK 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKCMGYCPQIN------------------PLWPDTTlqEHFEIYGAVK-GMSASDMKEVISRITHGLDLKE-HLQK 651
Cdd:PRK13631 95 NNHELITNPYSKKIKnfkelrrrvsmvfqfpeyQLFKDTI--EKDIMFGPVAlGVKKSEAKKLAKFYLNKMGLDDsYLER 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 652 TVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfKNRKRAAILTTHYMEEAEAVCDRVAIMVS 731
Cdd:PRK13631 173 SPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDA-KANNKTVFVITHTMEHVLEVADEVIVMDK 251
|
....*...
gi 16551961 732 GQLRCIGT 739
Cdd:PRK13631 252 GKILKTGT 259
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
513-734 |
4.52e-15 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 75.94 E-value: 4.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTI---INILVgdiEPTSGQVFLGDYSSET 589
Cdd:PRK11264 4 IEVKNLVKKFHGQ-----------TVLHGIDLEVKPGEVVAIIGPSGSGKTTLlrcINLLE---QPEAGTIRVGDITIDT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 SEDDGSLKCM--------GYCPQINPLWPDTTLQEHFeIYG--AVKGMSASDM----KEVISRIthGLDLKEhlQKTVKK 655
Cdd:PRK11264 70 ARSLSQQKGLirqlrqhvGFVFQNFNLFPHRTVLENI-IEGpvIVKGEPKEEAtaraRELLAKV--GLAGKE--TSYPRR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 656 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK11264 145 LSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIR-QLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
542-773 |
4.57e-15 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 77.82 E-value: 4.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSEDDgslKCMGYCpqinplwpdttlqehFEI 620
Cdd:PRK10851 21 ISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIrFHGTDVSRLHARD---RKVGFV---------------FQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 YGAVKGMSASD----------------MKEVISRITHGLDLK--EHL-QKTVKKLPAGIKRKLCFALSMLGNPQITLLDE 681
Cdd:PRK10851 83 YALFRHMTVFDniafgltvlprrerpnAAAIKAKVTQLLEMVqlAHLaDRYPAQLSGGQKQRVALARALAVEPQILLLDE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 682 PSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL----KSRFgkgyfleikl 757
Cdd:PRK10851 163 PFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVwrepATRF---------- 232
|
250
....*....|....*..
gi 16551961 758 kdWIENL-EVDRLQREI 773
Cdd:PRK10851 233 --VLEFMgEVNRLQGTI 247
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
513-739 |
7.43e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 75.89 E-value: 7.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDfllsrKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSED 592
Cdd:PRK13633 5 IKCKNVSYKYESNEE-----STEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 dgslkcmgycpqinpLW------------PD----TTLQEHFEIYGAVK-GMSASDMKEVISRITHGLDLKEHLQKTVKK 655
Cdd:PRK13633 80 ---------------LWdirnkagmvfqnPDnqivATIVEEDVAFGPENlGIPPEEIRERVDESLKKVGMYEYRRHAPHL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 656 LPAGIKRKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAeAVCDRVAIMVSGQ 733
Cdd:PRK13633 145 LSGGQKQRVAIAgiLAM--RPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGK 221
|
....*.
gi 16551961 734 LRCIGT 739
Cdd:PRK13633 222 VVMEGT 227
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
546-734 |
7.90e-15 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 74.07 E-value: 7.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYcpQINPLWPDTTLQEHFEIyGAVK 625
Cdd:cd03298 21 FAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLF--QENNLFAHLTVEQNVGL-GLSP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 626 G--MSASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFK 703
Cdd:cd03298 98 GlkLTAED-RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHA 176
|
170 180 190
....*....|....*....|....*....|.
gi 16551961 704 NRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03298 177 ETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
513-739 |
8.94e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 75.50 E-value: 8.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGdySSETSED 592
Cdd:PRK13639 2 LETRDLKYSYPDGT----------EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIK--GEPIKYD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSL----KCMGYCPQiNP---LWPDTTLQEhfEIYGAVK-GMSasdMKEVISRITHGL---DLKEHLQKTVKKLPAGIK 661
Cdd:PRK13639 70 KKSLlevrKTVGIVFQ-NPddqLFAPTVEED--VAFGPLNlGLS---KEEVEKRVKEALkavGMEGFENKPPHHLSGGQK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 662 RKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAfkNRKRAAI-LTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:PRK13639 144 KRVAIAgiLAM--KPEIIVLDEPTSGLDPMGASQIMKLLYDL--NKEGITIiISTHDVDLVPVYADKVYVMSDGKIIKEG 219
|
.
gi 16551961 739 T 739
Cdd:PRK13639 220 T 220
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
546-733 |
1.17e-14 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 74.75 E-value: 1.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssETSEDDGSLKcmgycPQ-INPLWPDTTLQEHFEIygaV 624
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDI-------EIELDTVSYK-----PQyIKADYEGTVRDLLSSI---T 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 KGMSASDmkEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKN 704
Cdd:cd03237 87 KDFYTHP--YFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAEN 164
|
170 180 190
....*....|....*....|....*....|.
gi 16551961 705 RKRAAILTTH--YMeeAEAVCDRVaIMVSGQ 733
Cdd:cd03237 165 NEKTAFVVEHdiIM--IDYLADRL-IVFEGE 192
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
533-746 |
2.94e-14 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 72.87 E-value: 2.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 533 KVKKVATKY------ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSsetseddgslkcmgyCPQIN 606
Cdd:COG3840 3 RLDDLTYRYgdfplrFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQD---------------LTALP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 607 P-------LWPDTTLQEHFEIYGAVK-GMSaSDMK---EVISRITHGLD---LKEHLQktvkKLPA----GIKRKLCFAL 668
Cdd:COG3840 68 PaerpvsmLFQENNLFPHLTVAQNIGlGLR-PGLKltaEQRAQVEQALErvgLAGLLD----RLPGqlsgGQRQRVALAR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 669 SMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSR 746
Cdd:COG3840 143 CLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDG 220
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
542-734 |
3.20e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 74.10 E-value: 3.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCM----GYCPQI--NPLWPDTTLQ 615
Cdd:PRK13641 26 ISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKKLrkkvSLVFQFpeAQLFENTVLK 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EhfEIYGAVK-GMSASDMKEVISRITHGLDLKEHL-QKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQH 693
Cdd:PRK13641 106 D--VEFGPKNfGFSEDEAKEKALKWLKKVGLSEDLiSKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKE 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 16551961 694 MWRairtAFKNRKRAA---ILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK13641 184 MMQ----LFKDYQKAGhtvILVTHNMDDVAEYADDVLVLEHGKL 223
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
542-714 |
3.53e-14 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 72.57 E-value: 3.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEddgSLKCMGYCPQINPLWPDTTLQEHFEIY 621
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD---RSRFMAYLGHLPGLKADLSTLENLHFL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDMKEVISRIthgLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIrTA 701
Cdd:PRK13543 107 CGLHGRRAKQMPGSALAI---VGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMI-SA 182
|
170
....*....|...
gi 16551961 702 FKNRKRAAILTTH 714
Cdd:PRK13543 183 HLRGGGAALVTTH 195
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
535-748 |
3.65e-14 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 76.70 E-value: 3.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQ--VFLGDYSSETSEDDgslkcmgYCPQI------- 605
Cdd:NF033858 13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRveVLGGDMADARHRRA-------VCPRIaympqgl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 --NpLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRK--LCFALsmLGNPQITLLDE 681
Cdd:NF033858 86 gkN-LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKlgLCCAL--IHDPDLLILDE 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 682 PSTGMDPKAKQHMWRAIrtafkNRKRAA------ILTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSRFG 748
Cdd:NF033858 163 PTTGVDPLSRRQFWELI-----DRIRAErpgmsvLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTG 229
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
499-739 |
3.94e-14 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 74.98 E-value: 3.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 499 KELMGCQCCEEKPSIMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSG 578
Cdd:PRK09452 1 SKKLNKQPSSLSPLVELRGISKSFDGKE-----------VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 579 QVFLgdyssetsedDGslKCMGYCP----QINPLWPDTTLQEHFEIYGAVK---GMSASDMKEVISRITHGL---DLKEH 648
Cdd:PRK09452 70 RIML----------DG--QDITHVPaenrHVNTVFQSYALFPHMTVFENVAfglRMQKTPAAEITPRVMEALrmvQLEEF 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 649 LQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMwraiRTAFKNRKRAA----ILTTHYMEEAEAVCD 724
Cdd:PRK09452 138 AQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQM----QNELKALQRKLgitfVFVTHDQEEALTMSD 213
|
250
....*....|....*
gi 16551961 725 RVAIMVSGQLRCIGT 739
Cdd:PRK09452 214 RIVVMRDGRIEQDGT 228
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
513-734 |
8.30e-14 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 71.41 E-value: 8.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSED 592
Cdd:cd03262 1 IEIKNLHKSFGDFH-----------VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSL--KCMGYCPQINPLWPDTTLQEHfeIYGA---VKGMSAsdmKEVISRITHGLD---LKEHLQKTVKKLPAGIKRKL 664
Cdd:cd03262 70 NINElrQKVGMVFQQFNLFPHLTVLEN--ITLApikVKGMSK---AEAEERALELLEkvgLADKADAYPAQLSGGQQQRV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 665 CFALSMLGNPQITLLDEPSTGMDPK------------AKQHMwrairtafknrkrAAILTTHYMEEAEAVCDRVAIMVSG 732
Cdd:cd03262 145 AIARALAMNPKVMLFDEPTSALDPElvgevldvmkdlAEEGM-------------TMVVVTHEMGFAREVADRVIFMDDG 211
|
..
gi 16551961 733 QL 734
Cdd:cd03262 212 RI 213
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
529-737 |
1.11e-13 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 74.44 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 529 LLSRKVKKVatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSLKCMGYCPQI-- 605
Cdd:PRK09700 271 VTSRDRKKV--RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLnGKDISPRSPLDAVKKGMAYITESrr 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 -NPLWPDTTLQEHFEIY---------GAVKGMSASDMKEVISRITHGLDLKEH-LQKTVKKLPAGIKRKLCFALSMLGNP 674
Cdd:PRK09700 349 dNGFFPNFSIAQNMAISrslkdggykGAMGLFHEVDEQRTAENQRELLALKCHsVNQNITELSGGNQQKVLISKWLCCCP 428
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:PRK09700 429 EVIIFDEPTRGIDVGAKAEIYKVMRQ-LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
526-746 |
1.20e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 72.14 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 526 KDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQi 605
Cdd:PRK13652 7 RDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQ- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 NP---LWPDTTLQEhfEIYGAVK-GMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDE 681
Cdd:PRK13652 86 NPddqIFSPTVEQD--IAFGPINlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 682 PSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSR 746
Cdd:PRK13652 164 PTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQ 228
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
519-751 |
1.21e-13 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 74.54 E-value: 1.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 519 HKEYDDKKDFLLSRK--VKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssetsEDDGSL 596
Cdd:PRK13545 18 NKPFDKLKDLFFRSKdgEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV----------DIKGSA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 597 KCMGYCPQINPlwpDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQI 676
Cdd:PRK13545 88 ALIAISSGLNG---QLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 677 TLLDEP-STGMDPKAKQHMWRAirTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFG---KGY 751
Cdd:PRK13545 165 LVIDEAlSVGDQTFTKKCLDKM--NEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDeflKKY 241
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
542-734 |
1.24e-13 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 70.90 E-value: 1.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysSETSEDDGSL-----KCMGYCPQINPLWPDTTLQE 616
Cdd:cd03292 20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNG--QDVSDLRGRAipylrRKIGVVFQDFRLLPDRNVYE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPkakQHMWR 696
Cdd:cd03292 98 NVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDP---DTTWE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 16551961 697 AIRTAFKNRKRAA--ILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:cd03292 175 IMNLLKKINKAGTtvVVATHAKELVDTTRHRVIALERGKL 214
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
542-741 |
1.32e-13 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 71.73 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-SETSEDDGSlKCMGYCPQINPLWPDTTLQEHFEI 620
Cdd:PRK13548 21 VSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPlADWSPAELA-RRRAVLPQHSSLSFPFTVEEVVAM 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 YGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFA--LSML----GNPQITLLDEPSTGMDPKAKQHM 694
Cdd:PRK13548 100 GRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLArvLAQLwepdGPPRWLLLDEPTSALDLAHQHHV 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 16551961 695 WRAIRTAFKNRKRAAI-------LTTHYmeeaeavCDRVAIMVSGQLRCIGTVQ 741
Cdd:PRK13548 180 LRLARQLAHERGLAVIvvlhdlnLAARY-------ADRIVLLHQGRLVADGTPA 226
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
546-716 |
1.60e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 74.46 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssetsedDGSLKcMGYCPQInpLWPDTTLQEHFEIYGAVK 625
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV------------DPELK-ISYKPQY--IKPDYDGTVEDLLRSITD 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 626 GMSASDMKeviSRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNR 705
Cdd:PRK13409 427 DLGSSYYK---SEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEER 503
|
170
....*....|...
gi 16551961 706 KRAAILTTH--YM 716
Cdd:PRK13409 504 EATALVVDHdiYM 516
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
542-745 |
1.70e-13 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 71.20 E-value: 1.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINIL-VGDIePTSGQVFLG----DYSSETSEDDGSL--KCMGYCPQINPLWPD-TT 613
Cdd:COG4161 21 INLECPSGETLVLLGPSGAGKSSLLRVLnLLET-PDSGQLNIAghqfDFSQKPSEKAIRLlrQKVGMVFQQYNLWPHlTV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 LQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQH 693
Cdd:COG4161 100 MENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQ 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 16551961 694 MWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:COG4161 180 VVEIIRE-LSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDASHFTQ 230
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
509-752 |
1.88e-13 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 74.09 E-value: 1.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 509 EKPSIMVSNLHKEYDDKKDFLLSRkvkkvatkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-S 587
Cdd:PRK11160 335 DQVSLTLNNVSFTYPDQPQPVLKG---------LSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPiA 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 588 ETSEDDgsLK-CMGYCPQINPLWPDtTLQEHFEIYGAvkgmSASD--MKEVISRIthGLdlkEHLQKTVKKLPA------ 658
Cdd:PRK11160 406 DYSEAA--LRqAISVVSQRVHLFSA-TLRDNLLLAAP----NASDeaLIEVLQQV--GL---EKLLEDDKGLNAwlgegg 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 659 -----GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMEEAEAVcDRVAIMVSGQ 733
Cdd:PRK11160 474 rqlsgGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQN--KTVLMITHRLTGLEQF-DRICVMDNGQ 550
|
250
....*....|....*....
gi 16551961 734 LRCIGTVQHLKSRFGkGYF 752
Cdd:PRK11160 551 IIEQGTHQELLAQQG-RYY 568
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
542-734 |
2.20e-13 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 70.08 E-value: 2.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYssetseDDGSLK---------CMGYCPQINPLWPDT 612
Cdd:COG2884 21 VSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQ------DLSRLKrreipylrrRIGVVFQDFRLLPDR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 613 TLQEHFEIYGAVKGMSASDMKEvisRITHGLD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK 689
Cdd:COG2884 95 TVYENVALPLRVTGKSRKEIRR---RVREVLDlvgLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADEPTGNLDPE 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16551961 690 AKQHMWRAIRTAfkNRKRAAIL-TTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:COG2884 172 TSWEIMELLEEI--NRRGTTVLiATHDLELVDRMPKRVLELEDGRL 215
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
542-742 |
7.92e-13 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 68.89 E-value: 7.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG----DYSSETSEDDGSL--KCMGYCPQINPLWPDTTLQ 615
Cdd:PRK11124 21 ITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAgnhfDFSKTPSDKAIRElrRNVGMVFQQYNLWPHLTVQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHF-EIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHM 694
Cdd:PRK11124 101 QNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQI 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 16551961 695 WRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQH 742
Cdd:PRK11124 181 VSIIR-ELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC 227
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
542-748 |
1.16e-12 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 70.64 E-value: 1.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQinplwpDTTLQEHFEIY 621
Cdd:PRK09536 22 VDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASVPQ------DTSLSFEFDVR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVK-----------GMSASDMKEVISRITHGlDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDpka 690
Cdd:PRK09536 96 QVVEmgrtphrsrfdTWTETDRAAVERAMERT-GVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD--- 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 691 kqhMWRAIRTAFKNRK-----RAAILTTHYMEEAEAVCDRVAIMVSGQLRCIG------TVQHLKSRFG 748
Cdd:PRK09536 172 ---INHQVRTLELVRRlvddgKTAVAAIHDLDLAARYCDELVLLADGRVRAAGppadvlTADTLRAAFD 237
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
510-734 |
1.45e-12 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 68.65 E-value: 1.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 510 KPSIMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINIL--VGDIEP---TSGQV-FLG 583
Cdd:PRK14239 3 EPILQVSDLSVYYNKKK-----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPevtITGSIvYNG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 584 D--YSSETseDDGSL-KCMGYC-PQINPlWPdTTLQEHFeIYG-AVKGM-SASDMKEVISRITHGL----DLKEHLQKTV 653
Cdd:PRK14239 72 HniYSPRT--DTVDLrKEIGMVfQQPNP-FP-MSIYENV-VYGlRLKGIkDKQVLDEAVEKSLKGAsiwdEVKDRLHDSA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 654 KKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQhmwRAIRTAFKNRKRAAILT-THYMEEAEAVCDRVAIMVSG 732
Cdd:PRK14239 147 LGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAG---KIEETLLGLKDDYTMLLvTRSMQQASRISDRTGFFLDG 223
|
..
gi 16551961 733 QL 734
Cdd:PRK14239 224 DL 225
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
542-734 |
1.48e-12 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 70.85 E-value: 1.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssETSEDDGSLKCMG----YCP---QINPLWPDTTL 614
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNG---KEINALSTAQRLArglvYLPedrQSSGLYLDAPL 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 qehfeiYGAVKGMSASDM---------KEVISRITHGLDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPST 684
Cdd:PRK15439 359 ------AWNVCALTHNRRgfwikpareNAVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTR 432
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 16551961 685 GMDPKAKQHMWRAIRTAFKnRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK15439 433 GVDVSARNDIYQLIRSIAA-QNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
521-749 |
1.88e-12 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 67.64 E-value: 1.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 521 EYDDKKDFLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSEtsedDGSLKC-- 598
Cdd:cd03251 9 RYPGDGPPVL---------RDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVR----DYTLASlr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 599 --MGYCPQiNPLWPDTTLQEHFEiYGAvkgmSASDMKEVIS--RITHGLDLKEHLQK---TV-----KKLPAGIKRKLCF 666
Cdd:cd03251 76 rqIGLVSQ-DVFLFNDTVAENIA-YGR----PGATREEVEEaaRAANAHEFIMELPEgydTVigergVKLSGGQRQRIAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 667 ALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAI---LTThyMEEAeavcDRVAIMVSGQLRCIGTVQHL 743
Cdd:cd03251 150 ARALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIahrLST--IENA----DRIVVLEDGKIVERGTHEEL 223
|
....*.
gi 16551961 744 KSRFGK 749
Cdd:cd03251 224 LAQGGV 229
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
542-734 |
2.78e-12 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 69.94 E-value: 2.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD----YSSETSEDDGSLKCMgYcpQINPLWPDTTLQEH 617
Cdd:PRK11288 23 ISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGqemrFASTTAALAAGVAII-Y--QELHLVPEMTVAEN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 feIY--------GAVKGMSAsdMKEVISRITH-GLDLKEHLQktVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:PRK11288 100 --LYlgqlphkgGIVNRRLL--NYEAREQLEHlGVDIDPDTP--LKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSA 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16551961 689 KAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK11288 174 REIEQLFRVIR-ELRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
547-699 |
2.96e-12 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 70.20 E-value: 2.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 547 KKGEILGLLGPNGAGKSTIINILVGDIEPTsgqvfLGDYSSETSEDDGSLKCMGycpqinplwpdTTLQEHFE------- 619
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKILSGELKPN-----LGDYDEEPSWDEVLKRFRG-----------TELQDYFKklangei 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 -----------IYGAVKG-----MSASD----MKEVISRithgLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLL 679
Cdd:COG1245 161 kvahkpqyvdlIPKVFKGtvrelLEKVDergkLDELAEK----LGLENILDRDISELSGGELQRVAIAAALLRDADFYFF 236
|
170 180
....*....|....*....|
gi 16551961 680 DEPSTGMDPKAKQHMWRAIR 699
Cdd:COG1245 237 DEPSSYLDIYQRLNVARLIR 256
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
542-739 |
3.28e-12 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 67.32 E-value: 3.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-----YSSETSEDDGSLKCMgycpQINPLWPDTTLQE 616
Cdd:PRK11300 24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGqhiegLPGHQIARMGVVRTF----QHVRLFREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEI-------YGAVKGMSASDM-----KEVISRITHGLD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDE 681
Cdd:PRK11300 100 NLLVaqhqqlkTGLFSGLLKTPAfrraeSEALDRAATWLErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDE 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 682 PSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:PRK11300 180 PAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGT 237
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
546-729 |
3.81e-12 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 65.72 E-value: 3.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-----YSSETSEDDGSLKC-------MGycpqinpLWPDTt 613
Cdd:NF040873 15 IPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGgarvaYVPQRSEVPDSLPLtvrdlvaMG-------RWARR- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 lqehfeiyGAVKGMSASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQH 693
Cdd:NF040873 87 --------GLWRRLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRER 157
|
170 180 190
....*....|....*....|....*....|....*.
gi 16551961 694 MWRAIRtAFKNRKRAAILTTHYMEEAEAVcDRVAIM 729
Cdd:NF040873 158 IIALLA-EEHARGATVVVVTHDLELVRRA-DPCVLL 191
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
538-787 |
4.49e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 67.32 E-value: 4.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSLKCMGYCPQiNP--LWPDTTL 614
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVsGIDTGDFSKLQGIRKLVGIVFQ-NPetQFVGRTV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHM 694
Cdd:PRK13644 96 EEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 695 WRAIRTaFKNRKRAAILTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSRFGKGYfLEIKLKDWIENLEvdRLQR-EI 773
Cdd:PRK13644 176 LERIKK-LHEKGKTIVYITHNLEELHDA-DRIIVMDRGKIVLEGEPENVLSDVSLQT-LGLTPPSLIELAE--NLKMhGV 250
|
250
....*....|....
gi 16551961 774 QYIFPNASRQESFS 787
Cdd:PRK13644 251 VIPWENTSSPSSFA 264
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
542-739 |
4.55e-12 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 66.96 E-value: 4.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEiY 621
Cdd:PRK11231 21 LSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLPQHHLTPEGITVRELVA-Y 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 G-----AVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWR 696
Cdd:PRK11231 100 GrspwlSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMR 179
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 697 AIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:PRK11231 180 LMRE-LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGT 221
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
542-734 |
5.20e-12 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 69.28 E-value: 5.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD--YSSETSEDdgSLKC-MGYCP---QINPLWPDTTLQ 615
Cdd:COG1129 271 VSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpVRIRSPRD--AIRAgIAYVPedrKGEGLVLDLSIR 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 E-----HFEIYGAVKGMSASDMKEVISRITHGLDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK 689
Cdd:COG1129 349 EnitlaSLDRLSRGGLLDRRRERALAEEYIKRLRIKtPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVG 428
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 16551961 690 AKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:COG1129 429 AKAEIYRLIR-ELAAEGKAVIVISSELPELLGLSDRILVMREGRI 472
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
546-705 |
5.26e-12 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 69.45 E-value: 5.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTsgqvfLGDYSSETSEDD------GslkcmgycpqinplwpdTTLQEHFE 619
Cdd:PRK13409 96 PKEGKVTGILGPNGIGKTTAVKILSGELIPN-----LGDYEEEPSWDEvlkrfrG-----------------TELQNYFK 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 ------------------IYGAVKGmSASD----------MKEVISRithgLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:PRK13409 154 klyngeikvvhkpqyvdlIPKVFKG-KVREllkkvdergkLDEVVER----LGLENILDRDISELSGGELQRVAIAAALL 228
|
170 180 190
....*....|....*....|....*....|....
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNR 705
Cdd:PRK13409 229 RDADFYFFDEPTSYLDIRQRLNVARLIRELAEGK 262
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
546-746 |
6.43e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 66.47 E-value: 6.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIE-----PTSGQVFLGD---YSSETSEDDGSLKCMGYCPqiNPLwPDTTLQEH 617
Cdd:PRK14247 26 IPDNTITALMGPSGSGKSTLLRVFNRLIElypeaRVSGEVYLDGqdiFKMDVIELRRRVQMVFQIP--NPI-PNLSIFEN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FEIyGAVKGMSASDMKEVISRITHGLD-------LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK- 689
Cdd:PRK14247 103 VAL-GLKLNRLVKSKKELQERVRWALEkaqlwdeVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPEn 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 690 -AKqhmwraIRTAFKNRKR--AAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSR 746
Cdd:PRK14247 182 tAK------IESLFLELKKdmTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTN 235
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
546-714 |
7.22e-12 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 66.62 E-value: 7.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTsgqvfLGDYSSETSEDDgslkcmgycpqINPLWPDTTLQEHFE------ 619
Cdd:cd03236 23 PREGQVLGLVGPNGIGKSTALKILAGKLKPN-----LGKFDDPPDWDE-----------ILDEFRGSELQNYFTkllegd 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 ------------IYGAVKG-----MSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEP 682
Cdd:cd03236 87 vkvivkpqyvdlIPKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEP 166
|
170 180 190
....*....|....*....|....*....|..
gi 16551961 683 STGMDPKAKQHMWRAIRTAFKNrKRAAILTTH 714
Cdd:cd03236 167 SSYLDIKQRLNAARLIRELAED-DNYVLVVEH 197
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
533-739 |
9.47e-12 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 65.13 E-value: 9.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 533 KVKKVATKY----------ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYC 602
Cdd:cd03369 8 EVENLSVRYapdlppvlknVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTII 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 603 PQiNPLWPDTTLQEHFEIYGAvkgMSASDMKEVISRITHGLDLKehlqktvkklpAGIKRKLCFALSMLGNPQITLLDEP 682
Cdd:cd03369 88 PQ-DPTLFSGTIRSNLDPFDE---YSDEEIYGALRVSEGGLNLS-----------QGQRQLLCLARALLKRPRVLVLDEA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 683 STGMDPKAKQHMWRAIRTAFKNrkrAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGT 739
Cdd:cd03369 153 TASIDYATDALIQKTIREEFTN---STILTIAHRLRTIIDYDKILVMDAGEVKEYDH 206
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
546-735 |
1.03e-11 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 65.57 E-value: 1.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSL---KCMGYCPQINPLWPDTTLQEHFEIY 621
Cdd:PRK10584 33 VKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLvGQPLHQMDEEARAKlraKHVGFVFQSFMLIPTLNALENVELP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQhmwRAIRTA 701
Cdd:PRK10584 113 ALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGD---KIADLL 189
|
170 180 190
....*....|....*....|....*....|....*..
gi 16551961 702 FK-NRKRAA--ILTTHYMEEAeAVCDRVAIMVSGQLR 735
Cdd:PRK10584 190 FSlNREHGTtlILVTHDLQLA-ARCDRRLRLVNGQLQ 225
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
513-740 |
1.11e-11 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 67.13 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsRKVkkVATKYISFCVKKGEILGLLGPNGAGKST---IINILVgdiEPTSGQVFLGDysset 589
Cdd:PRK11153 2 IELKNISKVFPQGG-----RTI--HALNNVSLHIPAGEIFGVIGASGAGKSTlirCINLLE---RPTSGRVLVDG----- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 590 sEDDGSLKcmgycpqinplwpDTTLQE----------HFE------IYGAV------KGMSASDMKeviSRITHGLDLKE 647
Cdd:PRK11153 67 -QDLTALS-------------EKELRKarrqigmifqHFNllssrtVFDNValplelAGTPKAEIK---ARVTELLELVG 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 648 hLQKTVKKLPA----------GIKRklcfALSMlgNPQITLLDEPSTGMDPKAKqhmwRAIRTAFK--NRKR--AAILTT 713
Cdd:PRK11153 130 -LSDKADRYPAqlsggqkqrvAIAR----ALAS--NPKVLLCDEATSALDPATT----RSILELLKdiNRELglTIVLIT 198
|
250 260
....*....|....*....|....*..
gi 16551961 714 HYMEEAEAVCDRVAIMVSGQLRCIGTV 740
Cdd:PRK11153 199 HEMDVVKRICDRVAVIDAGRLVEQGTV 225
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
542-751 |
1.37e-11 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 65.49 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIY 621
Cdd:PRK11248 20 INLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITL-----DGKPVEGPGAERGVVFQNEGLLPWRNVQDNVAFG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTA 701
Cdd:PRK11248 95 LQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQTLLLKL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 16551961 702 FKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRcigTVQHLKSRFGKGY 751
Cdd:PRK11248 175 WQETGKQVLLITHDIEEAVFMATELVLLSPGPGR---VVERLPLNFARRF 221
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
515-687 |
1.56e-11 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 67.61 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKDFllsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdYSSETSEddg 594
Cdd:PRK15064 322 VENLTKGFDNGPLF-----------KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV----KWSENAN--- 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 slkcMGYCPQINPLW--PDTTLQEHFEIYG-------AVKGM------SASDMKevisrithgldlkehlqKTVKKLPAG 659
Cdd:PRK15064 384 ----IGYYAQDHAYDfeNDLTLFDWMSQWRqegddeqAVRGTlgrllfSQDDIK-----------------KSVKVLSGG 442
|
170 180
....*....|....*....|....*...
gi 16551961 660 IKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK15064 443 EKGRMLFGKLMMQKPNVLVMDEPTNHMD 470
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
513-734 |
1.84e-11 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 66.25 E-value: 1.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsRKVkkVATKYISFCVKKGEILGLLGPNGAGKST---IINILvgdiE-PTSGQVFLGDysse 588
Cdd:COG1135 2 IELENLSKTFPTKG-----GPV--TALDDVSLTIEKGEIFGIIGYSGAGKSTlirCINLL----ErPTSGSVLVDG---- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 589 tsEDDGSL---------KCMGYCPQinplwpdttlqeHFE------IYGAV------KGMSASDMKEvisRITHGLDL-- 645
Cdd:COG1135 67 --VDLTALserelraarRKIGMIFQ------------HFNllssrtVAENValpleiAGVPKAEIRK---RVAELLELvg 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 646 ---KEHlqktvkKLPA----------GIKRklcfALSMlgNPQITLLDEPSTGMDPKAKQhmwrAIRTAFK--NRKRAA- 709
Cdd:COG1135 130 lsdKAD------AYPSqlsggqkqrvGIAR----ALAN--NPKVLLCDEATSALDPETTR----SILDLLKdiNRELGLt 193
|
250 260
....*....|....*....|....*.
gi 16551961 710 -ILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:COG1135 194 iVLITHEMDVVRRICDRVAVLENGRI 219
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
542-741 |
2.18e-11 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 65.14 E-value: 2.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-SETSEDDGSlKCMGYCPQinplwpDTTLQEHF-- 618
Cdd:COG4559 20 VSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPlAAWSPWELA-RRRAVLPQ------HSSLAFPFtv 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 -EIYG---AVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFA--LSML-----GNPQITLLDEPSTGMD 687
Cdd:COG4559 93 eEVVAlgrAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLArvLAQLwepvdGGPRWLFLDEPTSALD 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 688 PKAKQHMWRAIRTaFKNRKRAAI-------LTTHYmeeaeavCDRVAIMVSGQLRCIGTVQ 741
Cdd:COG4559 173 LAHQHAVLRLARQ-LARRGGGVVavlhdlnLAAQY-------ADRILLLHQGRLVAQGTPE 225
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
509-687 |
2.19e-11 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 64.84 E-value: 2.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 509 EKPSIMVSNLHKEYDDKKdflLSRKVkkvaTKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS-- 586
Cdd:PRK11629 2 NKILLQCDNLCKRYQEGS---VQTDV----LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPms 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 587 --SETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKL 664
Cdd:PRK11629 75 klSSAAKAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRV 154
|
170 180
....*....|....*....|...
gi 16551961 665 CFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK11629 155 AIARALVNNPRLVLADEPTGNLD 177
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
549-743 |
2.22e-11 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 65.19 E-value: 2.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 549 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEI-----YGA 623
Cdd:PRK10575 37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRELVAIgrypwHGA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 624 VKGMSASDMKEVISRITHgLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFK 703
Cdd:PRK10575 117 LGRFGAADREKVEEAISL-VGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQ 195
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 16551961 704 NRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:PRK10575 196 ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
542-752 |
3.78e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 67.31 E-value: 3.78e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTT------LQ 615
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSPVLFSGTVrfnidpFS 1334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEIyGAVKGMSASDMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMW 695
Cdd:PLN03232 1335 EHNDA-DLWEALERAHIKDVIDRNPFGLDAE--VSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQ 1411
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 696 RAIRTAFKNrkrAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSRFGKGYF 752
Cdd:PLN03232 1412 RTIREEFKS---CTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFF 1465
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
513-732 |
4.04e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 64.76 E-value: 4.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSE 591
Cdd:PRK13647 5 IEVEDLHFRYKDGTK----------ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVkVMGREVNAENE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 --------------DDgslkcmgycpQI--NPLWPDTTlqehfeiYGAVK-GMSASDMKEVISRITHGLDLKEHLQKTVK 654
Cdd:PRK13647 75 kwvrskvglvfqdpDD----------QVfsSTVWDDVA-------FGPVNmGLDKDEVERRVEEALKAVRMWDFRDKPPY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 655 KLPAGIKRKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMwRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG 732
Cdd:PRK13647 138 HLSYGQKKRVAIAgvLAM--DPDVIVLDEPMAYLDPRGQETL-MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
542-714 |
4.17e-11 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 63.28 E-value: 4.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKC--MGYCPQINPLwpdTTLQEHFE 619
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLlyLGHAPGIKTT---LSVLENLR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 IYGAVKGMSAsdMKEVISRIthGLDLKEHLqkTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIR 699
Cdd:cd03231 96 FWHADHSDEQ--VEEALARV--GLNGFEDR--PVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMA 169
|
170
....*....|....*
gi 16551961 700 tAFKNRKRAAILTTH 714
Cdd:cd03231 170 -GHCARGGMVVLTTH 183
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
532-752 |
5.18e-11 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 66.22 E-value: 5.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 532 RKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEP---TSGQVFLgdyssetsedDG---SLKCM----GY 601
Cdd:TIGR00955 34 ERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLL----------NGmpiDAKEMraisAY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 602 CPQINPLWPDTTLQEHFEIYGAVK---GMSASDMKEVISRITHGLDLKEhLQKT-------VKKLPAGIKRKLCFALSML 671
Cdd:TIGR00955 104 VQQDDLFIPTLTVREHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRK-CANTrigvpgrVKGLSGGERKRLAFASELL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHyMEEAEAVC--DRVAIMVSGQLRCIGTVQHLKSRFGK 749
Cdd:TIGR00955 183 TDPPLLFCDEPTSGLDSFMAYSVVQVLK-GLAQKGKTIICTIH-QPSSELFElfDKIILMAEGRVAYLGSPDQAVPFFSD 260
|
...
gi 16551961 750 GYF 752
Cdd:TIGR00955 261 LGH 263
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
536-733 |
5.50e-11 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 63.95 E-value: 5.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 536 KVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLK---------------CMG 600
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDG------KDVTKLPeykrakyigrvfqdpMMG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 601 YCpqinplwPDTTLQEHFEI-------YGAVKGMSASDMKEVISRITH-GLDLKEHLQKTVKKLPAGiKRKlcfALSML- 671
Cdd:COG1101 93 TA-------PSMTIEENLALayrrgkrRGLRRGLTKKRRELFRELLATlGLGLENRLDTKVGLLSGG-QRQ---ALSLLm 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 672 ---GNPQITLLDEPSTGMDPK-AKQHMwRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:COG1101 162 atlTKPKLLLLDEHTAALDPKtAALVL-ELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
543-732 |
6.14e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 64.13 E-value: 6.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 543 SFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSEDDgslkCMGYCPQINPL-WPDTTLQEHFEI 620
Cdd:PRK15056 27 SFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKIsILGQPTRQALQKN----LVAYVPQSEEVdWSFPVLVEDVVM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 YGAVKGM------SASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHM 694
Cdd:PRK15056 103 MGRYGHMgwlrraKKRD-RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARI 181
|
170 180 190
....*....|....*....|....*....|....*...
gi 16551961 695 WRAIRtAFKNRKRAAILTTHYMEEAEAVCDrVAIMVSG 732
Cdd:PRK15056 182 ISLLR-ELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
543-734 |
6.18e-11 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 63.45 E-value: 6.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 543 SFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSLKcMGYcpQINPLWPDTTLQEHFEIy 621
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLnGQDHTTTPPSRRPVS-MLF--QENNLFSHLTVAQNIGL- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMS-ASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRT 700
Cdd:PRK10771 95 GLNPGLKlNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQ 174
|
170 180 190
....*....|....*....|....*....|....
gi 16551961 701 AFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK10771 175 VCQERQLTLLMVSHSLEDAARIAPRSLVVADGRI 208
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
542-733 |
6.49e-11 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 62.49 E-value: 6.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGdyssetseddGSlkcMGYCPQiNPLWPDTTLQEHFeIY 621
Cdd:cd03250 24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVP----------GS---IAYVSQ-EPWIQNGTIRENI-LF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVkgMSASDMKEVISRIthgldlkeHLQKTVKKLPAGI---------------KRKLCFALSMLGNPQITLLDEPSTGM 686
Cdd:cd03250 89 GKP--FDEERYEKVIKAC--------ALEPDLEILPDGDlteigekginlsggqKQRISLARAVYSDADIYLLDDPLSAV 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 16551961 687 DPKAKQHMW-RAIRTAFKNrKRAAILTTHYMEEAEAvCDRVAIMVSGQ 733
Cdd:cd03250 159 DAHVGRHIFeNCILGLLLN-NKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
536-745 |
7.68e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 65.64 E-value: 7.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 536 KVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGdieptsgqvFLgDYSsetseddGSLKCMG----------YCPQI 605
Cdd:PRK11174 363 KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLG---------FL-PYQ-------GSLKINGielreldpesWRKHL 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 -----NPLWPDTTLQEHF----------EIYGAVKgmsASDMKEVISRITHGLDLkehlqkTVKKLPAGIK----RKLCF 666
Cdd:PRK11174 426 swvgqNPQLPHGTLRDNVllgnpdasdeQLQQALE---NAWVSEFLPLLPQGLDT------PIGDQAAGLSvgqaQRLAL 496
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 667 ALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfkNRKRAAILTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:PRK11174 497 ARALLQPCQLLLLDEPTASLDAHSEQLVMQALNAA--SRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQ 572
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
512-773 |
1.32e-10 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 63.90 E-value: 1.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 512 SIMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDysSETSE 591
Cdd:PRK11000 3 SVTLRNVTKAYGDV-----------VISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGE--KRMND 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML 671
Cdd:PRK11000 70 VPPAERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL----KSRF 747
Cdd:PRK11000 150 AEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELyhypANRF 229
|
250 260 270
....*....|....*....|....*....|...
gi 16551961 748 GKGY-------FLEIKlkdwIENLEVDRLQREI 773
Cdd:PRK11000 230 VAGFigspkmnFLPVK----VTATAIEQVQVEL 258
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
515-732 |
1.45e-10 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 62.28 E-value: 1.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGD--IEPTSGQV-FLGDYSSETSE 591
Cdd:TIGR01978 3 IKDLHVSVEDKE--IL---------KGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHpsYEVTSGTIlFKGQDLLELEP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKCMGYCPQINPLWPDTTLQEhFeIYGAVKGMSASDMKEVISRithgLDLKEHLQKTVKKL---PAGIKRKL---- 664
Cdd:TIGR01978 72 DERARAGLFLAFQYPEEIPGVSNLE-F-LRSALNARRSARGEEPLDL----LDFEKLLKEKLALLdmdEEFLNRSVnegf 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 665 ---------CFALSMLgNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVC-DRVAIMVSG 732
Cdd:TIGR01978 146 sggekkrneILQMALL-EPKLAILDEIDSGLDIDALKIVAEGIN-RLREPDRSFLIITHYQRLLNYIKpDYVHVLLDG 221
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
542-734 |
1.53e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 62.80 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSEDDGSLK-CMGYCPQiNP--LWPDTTLQEHF 618
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKI-DGELLTAENVWNLRrKIGMVFQ-NPdnQFVGATVEDDV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAI 698
Cdd:PRK13642 104 AFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVI 183
|
170 180 190
....*....|....*....|....*....|....*..
gi 16551961 699 RtAFKNRKRAAILT-THYMEEAeAVCDRVAIMVSGQL 734
Cdd:PRK13642 184 H-EIKEKYQLTVLSiTHDLDEA-ASSDRILVMKAGEI 218
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
542-714 |
1.58e-10 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 61.36 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDD--GSLKCMGYCPQINplwPDTTLQEHFE 619
Cdd:PRK13538 20 LSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEyhQDLLYLGHQPGIK---TELTALENLR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 IYGAVKGM-SASDMKEVISRIthGLDLKEHLqkTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA----KQHM 694
Cdd:PRK13538 97 FYQRLHGPgDDEALWEALAQV--GLAGFEDV--PVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGvarlEALL 172
|
170 180
....*....|....*....|
gi 16551961 695 WRAIRtafknRKRAAILTTH 714
Cdd:PRK13538 173 AQHAE-----QGGMVILTTH 187
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
542-753 |
1.61e-10 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 62.12 E-value: 1.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWpDTTLQEHFEIy 621
Cdd:cd03252 21 ISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQENVLF-NRSIRDNIAL- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 gavkGMSASDMKEVI--SRITHG----LDLKEHLQKTVKK----LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAK 691
Cdd:cd03252 99 ----ADPGMSMERVIeaAKLAGAhdfiSELPEGYDTIVGEqgagLSGGQRQRIAIARALIHNPRILIFDEATSALDYESE 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 692 QHMWRAIRTAFKNrkRAAILTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSRFGKGYFL 753
Cdd:cd03252 175 HAIMRNMHDICAG--RTVIIIAHRLSTVKNA-DRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
542-741 |
2.97e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 62.08 E-value: 2.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQiNP--LWPDTTLQehFE 619
Cdd:PRK13648 28 VSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIGIVFQ-NPdnQFVGSIVK--YD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 IYGAVKGMSAS--DMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 697
Cdd:PRK13648 105 VAFGLENHAVPydEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDL 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 16551961 698 IRTAFKNRKRAAILTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQ 741
Cdd:PRK13648 185 VRKVKSEHNITIISITHDLSEA-MEADHVIVMNKGTVYKEGTPT 227
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
542-726 |
3.27e-10 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 60.88 E-value: 3.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDT---TLQEHF 618
Cdd:PRK10247 26 ISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYCAQTPTLFGDTvydNLIFPW 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGavkgmSASDMKEVISRITHgLDLKEH-LQKTVKKLPAGIKRKlcfaLSMLGN----PQITLLDEPSTGMDPKAKQH 693
Cdd:PRK10247 106 QIRN-----QQPDPAIFLDDLER-FALPDTiLTKNIAELSGGEKQR----ISLIRNlqfmPKVLLLDEITSALDESNKHN 175
|
170 180 190
....*....|....*....|....*....|...
gi 16551961 694 MWRAIRTAFKNRKRAAILTTHYMEEAEAvCDRV 726
Cdd:PRK10247 176 VNEIIHRYVREQNIAVLWVTHDKDEINH-ADKV 207
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
542-699 |
4.52e-10 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 59.95 E-value: 4.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINIL-----VGDIEptsGQVFLGDYSSetseDDGSLKCMGYCPQINPLWPDTTLQE 616
Cdd:cd03232 26 ISGYVKPGTLTALMGESGAGKTTLLDVLagrktAGVIT---GEILINGRPL----DKNFQRSTGYVEQQDVHSPNLTVRE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEIYGAVKGMSASDmkevisrithgldlkehlqktvkklpagiKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWR 696
Cdd:cd03232 99 ALRFSALLRGLSVEQ-----------------------------RKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVR 149
|
...
gi 16551961 697 AIR 699
Cdd:cd03232 150 FLK 152
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
515-739 |
4.81e-10 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 60.85 E-value: 4.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKdfLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVG--DIEPTSGQVFL-GDYSSETSE 591
Cdd:COG0396 3 IKNLHVSVEGKE--IL---------KGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILLdGEDILELSP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 592 DDGSLKCMGYCPQiNPLwpdttlqehfeiygAVKGMSASD-MKEVISRIT----HGLDLKEHLQKTVKKLpaGIKRKLC- 665
Cdd:COG0396 72 DERARAGIFLAFQ-YPV--------------EIPGVSVSNfLRTALNARRgeelSAREFLKLLKEKMKEL--GLDEDFLd 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 666 -----------------FALSMLgNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHY---MEEAEAvcDR 725
Cdd:COG0396 135 ryvnegfsggekkrneiLQMLLL-EPKLAILDETDSGLDIDALRIVAEGVN-KLRSPDRGILIITHYqriLDYIKP--DF 210
|
250
....*....|....
gi 16551961 726 VAIMVSGQLRCIGT 739
Cdd:COG0396 211 VHVLVDGRIVKSGG 224
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
546-759 |
5.44e-10 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 59.51 E-value: 5.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGqvflgdyssetseddgslkcmgycpqiNPLWPDTTLqehfeiygAVK 625
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGD---------------------------NDEWDGITP--------VYK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 626 GmsasdmkevisrithgldlkehlQKTvkKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNR 705
Cdd:cd03222 67 P-----------------------QYI--DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEG 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 706 KRAAILTTHYMEEAEAVCDRVaIMVSGQLRCIGTVQHLKS-RFGKGYFLEIKLKD 759
Cdd:cd03222 122 KKTALVVEHDLAVLDYLSDRI-HVFEGEPGVYGIASQPKGtREGINRFLRGYLIT 175
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
535-734 |
7.47e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 60.97 E-value: 7.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTI---IN-ILVGDIEPTSGQVFLGDYSSETSEDDGSLKcMGYCPQiNP--L 608
Cdd:PRK13640 19 KKPALNDISFSIPRGSWTALIGHNGSGKSTIsklINgLLLPDDNPNSKITVDGITLTAKTVWDIREK-VGIVFQ-NPdnQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 609 WPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:PRK13640 97 FVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDP 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 16551961 689 KAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEaVCDRVAIMVSGQL 734
Cdd:PRK13640 177 AGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKL 221
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
542-734 |
7.53e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 62.33 E-value: 7.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-----------------YSSETSEDDG---------- 594
Cdd:PRK10762 271 VSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGhevvtrspqdglangivYISEDRKRDGlvlgmsvken 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 595 -SLKCMGYCPQinplwpdttlqEHFEIYGAVKGMSASDMKEVISRITHGLDlkehlqKTVKKLPAGIKRKLCFALSMLGN 673
Cdd:PRK10762 351 mSLTALRYFSR-----------AGGSLKHADEQQAVSDFIRLFNIKTPSME------QAIGLLSGGNQQKVAIARGLMTR 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 674 PQITLLDEPSTGMDPKAKQHMWRAIrTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK10762 414 PKVLILDEPTRGVDVGAKKEIYQLI-NQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
513-743 |
9.66e-10 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 60.25 E-value: 9.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLLsrkvkkvatKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEpTSGQVFLGDYSSETSED 592
Cdd:cd03289 3 MTVKDLTAKYTEGGNAVL---------ENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKCMGYCPQINPLWpDTTLQEHFEIYGA------VKGMSASDMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCF 666
Cdd:cd03289 73 QKWRKAFGVIPQKVFIF-SGTFRKNLDPYGKwsdeeiWKVAEEVGLKSVIEQFPGQLDFV--LVDGGCVLSHGHKQLMCL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 667 ALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNrkRAAILTTHYMeEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:cd03289 150 ARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFAD--CTVILSEHRI-EAMLECQRFLVIEENKVRQYDSIQKL 223
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
513-734 |
1.04e-09 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 59.98 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTI---INILVgdiEPTSGQVFL-GDYSSE 588
Cdd:PRK10619 6 LNVIDLHKRYGEHE-----------VLKGVSLQANAGDVISIIGSSGSGKSTFlrcINFLE---KPSEGSIVVnGQTINL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 589 TSEDDGSLKC------------MGYCPQINPLWPDTTLQEH-FEIYGAVKGMSASDMKEVISRITHGLDLKEHLQ-KTVK 654
Cdd:PRK10619 72 VRDKDGQLKVadknqlrllrtrLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPV 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 655 KLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRaIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK10619 152 HLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLR-IMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
540-734 |
1.32e-09 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 59.41 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-----GDYSSETSEDDGSLkcMGYCPQINPlwpdTTL 614
Cdd:cd03248 31 QDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLdgkpiSQYEHKYLHSKVSL--VGQEPVLFA----RSL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHFEiYG--------AVKGMSASDMKEVISRITHGLDlkEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGM 686
Cdd:cd03248 105 QDNIA-YGlqscsfecVKEAAQKAHAHSFISELASGYD--TEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSAL 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 16551961 687 DPKAKQHMWRAIRTAfkNRKRAAILTTHYMEEAEAVcDRVAIMVSGQL 734
Cdd:cd03248 182 DAESEQQVQQALYDW--PERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
542-714 |
1.47e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 58.42 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS--SETSEDDGSLKCMGYCPQINplwPDTTLQEH-- 617
Cdd:PRK13540 20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSikKDLCTYQKQLCFVGHRSGIN---PYLTLRENcl 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FEIYGAVKGMSASDMKEVISrITHGLDLKEHLqktvkkLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRA 697
Cdd:PRK13540 97 YDIHFSPGAVGITELCRLFS-LEHLIDYPCGL------LSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITK 169
|
170
....*....|....*..
gi 16551961 698 IRtAFKNRKRAAILTTH 714
Cdd:PRK13540 170 IQ-EHRAKGGAVLLTSH 185
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
511-781 |
1.90e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 59.28 E-value: 1.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 511 PSIMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTII------NILVGDIEpTSGQV-FLG 583
Cdd:PRK14258 6 PAIKVNNLSFYYDTQK-----------ILEGVSMEIYQSKVTAIIGPSGCGKSTFLkclnrmNELESEVR-VEGRVeFFN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 584 DYSSETSEDDGSLK---CMGYC-PQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLD-LKEHLQKTVKKLPA 658
Cdd:PRK14258 74 QNIYERRVNLNRLRrqvSMVHPkPNLFPMSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDeIKHKIHKSALDLSG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 659 GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCig 738
Cdd:PRK14258 154 GQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENRI-- 231
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 16551961 739 tvqhlksrfgkGYFLEIKLKDWIENLEVDRLQREiqYIFPNAS 781
Cdd:PRK14258 232 -----------GQLVEFGLTKKIFNSPHDSRTRE--YVLSRLG 261
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
551-745 |
2.14e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 59.34 E-value: 2.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 551 ILGLLGPNGAGKSTIINILVGDIEPTSG-----QVFLGDYSSETSEDDGSLKC-MGYCPQINPLWPDTTLQEHFEIYGAV 624
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNYRDVLEFRRrVGMLFQRPNPFPMSIMDNVLAGVRAH 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 KGMSASDMKEVI-SRITH-GL--DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRT 700
Cdd:PRK14271 129 KLVPRKEFRGVAqARLTEvGLwdAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRS 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 16551961 701 AFKnrKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:PRK14271 209 LAD--RLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFS 251
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
513-687 |
3.71e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 60.33 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsed 592
Cdd:TIGR03719 323 IEAENLTKAFGDK-----------LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGE-------- 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 dgSLKcMGYCPQI-NPLWPDTTLQEhfEIYGAVKGMSASDmKEVISRIT------HGLDlkehLQKTVKKLPAGIKRKLC 665
Cdd:TIGR03719 384 --TVK-LAYVDQSrDALDPNKTVWE--EISGGLDIIKLGK-REIPSRAYvgrfnfKGSD----QQKKVGQLSGGERNRVH 453
|
170 180
....*....|....*....|..
gi 16551961 666 FALSMLGNPQITLLDEPSTGMD 687
Cdd:TIGR03719 454 LAKTLKSGGNVLLLDEPTNDLD 475
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
531-731 |
3.90e-09 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 57.66 E-value: 3.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 531 SRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIE--PTSGQVFLGDyssetseddgslkcmgycpqiNPL 608
Cdd:COG2401 38 LRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPD---------------------NQF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 609 WPDTTLQEHFEIYGAVKgmsasDMKEVISRIthGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:COG2401 97 GREASLIDAIGRKGDFK-----DAVELLNAV--GLSDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 16551961 689 KAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVS 731
Cdd:COG2401 170 QTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFVG 212
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
540-748 |
3.91e-09 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 60.51 E-value: 3.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSEDDGSL-KCMGYCPQINPLWPDT------ 612
Cdd:TIGR00958 498 KGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLL-DGVPLVQYDHHYLhRQVALVGQEPVLFSGSvrenia 576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 613 ---TLQEHFEIYGAVKGMSASDMkevISRITHGLD--LKEHLQktvkKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:TIGR00958 577 yglTDTPDEEIMAAAKAANAHDF---IMEFPNGYDteVGEKGS----QLSGGQKQRIAIARALVRKPRVLILDEATSALD 649
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 688 PKAKQhmwrAIRTAFKNRKRAAILTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSRFG 748
Cdd:TIGR00958 650 AECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQG 705
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
508-763 |
4.11e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 58.11 E-value: 4.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 508 EEKPSIMVSNLHKEYDDKKdfllsrkvkkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVG---------------- 571
Cdd:CHL00131 3 KNKPILEIKNLHASVNENE-----------ILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpaykilegdilfkge 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 572 ---DIEPTSGQ---VFLG-DYSSE----TSED------DGSLKCMGYcPQINPLwpdttlqEHFEIygavkgmsasdmke 634
Cdd:CHL00131 72 silDLEPEERAhlgIFLAfQYPIEipgvSNADflrlayNSKRKFQGL-PELDPL-------EFLEI-------------- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 635 vISRITHGLDLKEH-LQKTVKKLPAGIKRKLCFALSM-LGNPQITLLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILT 712
Cdd:CHL00131 130 -INEKLKLVGMDPSfLSRNVNEGFSGGEKKRNEILQMaLLDSELAILDETDSGLDIDALKIIAEGINK-LMTSENSIILI 207
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 16551961 713 THYMEEAEAVC-DRVAIMVSGQLRCIGTVQHLKSRFGKGYfleiklkDWIEN 763
Cdd:CHL00131 208 THYQRLLDYIKpDYVHVMQNGKIIKTGDAELAKELEKKGY-------DWLKQ 252
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
542-748 |
8.28e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 59.57 E-value: 8.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssetsedDGSLkcmGYCPQinPLW-PDTTLQEHFeI 620
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHM----------KGSV---AYVPQ--QAWiQNDSLRENI-L 720
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 YGavKGMSASDMKEVIS--------RITHGLDLKEHLQKTVkKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQ 692
Cdd:TIGR00957 721 FG--KALNEKYYQQVLEacallpdlEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGK 797
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 693 HMWRAI---RTAFKNRKRaaILTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSRFG 748
Cdd:TIGR00957 798 HIFEHVigpEGVLKNKTR--ILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
542-722 |
8.83e-09 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 56.34 E-value: 8.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEP---TSGQVFLGDysseTSEDDGS--LKCMGYCPQINPLWPdttlqe 616
Cdd:COG4136 20 LSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNG----RRLTALPaeQRRIGILFQDDLLFP------ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEI-----YGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAK 691
Cdd:COG4136 90 HLSVgenlaFALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALR 169
|
170 180 190
....*....|....*....|....*....|.
gi 16551961 692 QHMWRAIRTAFKNRKRAAILTTHYMEEAEAV 722
Cdd:COG4136 170 AQFREFVFEQIRQRGIPALLVTHDEEDAPAA 200
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
543-748 |
9.13e-09 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 56.78 E-value: 9.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 543 SFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetsEDDGSLKC------MGYCPQiNPLWPDTTLQE 616
Cdd:cd03249 23 SLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDG------VDIRDLNLrwlrsqIGLVSQ-EPVLFDGTIAE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEiYGAVKGMSASDMK--------EVISRITHGLDlkEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:cd03249 96 NIR-YGKPDATDEEVEEaakkanihDFIMSLPDGYD--TLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATSALDA 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 689 KAKQHMWRAIRTAFKNRKRAAI---LTThymeeaeaV--CDRVAIMVSGQLRCIGTVQHLKSRFG 748
Cdd:cd03249 173 ESEKLVQEALDRAMKGRTTIVIahrLST--------IrnADLIAVLQNGQVVEQGTHDELMAQKG 229
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
542-729 |
9.33e-09 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 56.67 E-value: 9.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssetsEDDGSL----------------KCMGYCPQ- 604
Cdd:COG4778 30 VSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILV--------RHDGGWvdlaqaspreilalrrRTIGYVSQf 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 605 -------------INPLwpdttlqehfeiygAVKGMSASDMKEVISRITHGLDLKEHLQKTVkklPA----GIKRKLCFA 667
Cdd:COG4778 102 lrviprvsaldvvAEPL--------------LERGVDREEARARARELLARLNLPERLWDLP---PAtfsgGEQQRVNIA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 668 LSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfKNRKRAAILTTHYMEEAEAVCDRVAIM 729
Cdd:COG4778 165 RGFIADPPLLLLDEPTASLDAANRAVVVELIEEA-KARGTAIIGIFHDEEVREAVADRVVDV 225
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
551-738 |
9.52e-09 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 57.32 E-value: 9.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 551 ILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG----DYSSEtseddgslKCMGYCPQINPLWPDTTLQEHF-----EIY 621
Cdd:PRK13638 29 VTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQgkplDYSKR--------GLLALRQQVATVFQDPEQQIFYtdidsDIA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 GAVKGMSASDmKEVISRITHGL---DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAI 698
Cdd:PRK13638 101 FSLRNLGVPE-AEITRRVDEALtlvDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAII 179
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 16551961 699 RTAFKNRKRaAILTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:PRK13638 180 RRIVAQGNH-VIISSHDIDLIYEISDAVYVLRQGQILTHG 218
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
542-699 |
9.78e-09 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 56.81 E-value: 9.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQ-VFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFei 620
Cdd:PRK11614 24 VSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRiVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENL-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 ygAVKGMSAsDMKEVISRITHGLDLKEHLQ----KTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWR 696
Cdd:PRK11614 102 --AMGGFFA-ERDQFQERIKWVYELFPRLHerriQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFD 178
|
...
gi 16551961 697 AIR 699
Cdd:PRK11614 179 TIE 181
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
538-751 |
1.25e-08 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 56.94 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTII----NILVGDIEPTSGQVFLGDysseTSEDDGSLK--------CMGYCPQI 605
Cdd:PRK09984 19 ALHAVDLNIHHGEMVALLGPSGSGKSTLLrhlsGLITGDKSAGSHIELLGR----TVQREGRLArdirksraNTGYIFQQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 606 NPLWPDTTLQEHFEIyGA----------VKGMSASDMKEVISRITHgLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQ 675
Cdd:PRK09984 95 FNLVNRLSVLENVLI-GAlgstpfwrtcFSWFTREQKQRALQALTR-VGMVHFAHQRVSTLSGGQQQRVAIARALMQQAK 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 676 ITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS-RFGKGY 751
Cdd:PRK09984 173 VILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQFDNeRFDHLY 249
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
143-402 |
1.38e-08 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 57.40 E-value: 1.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 143 SADSDISDLISFFTSQNIMVTMIN-DSDYVSVAPHSAALNVMhSEKDYVFAAVFNSTMVYSLPILVNIISNYY------- 214
Cdd:pfam12698 53 EASPTVNLVQYVDSEEEAKEALKNgKIDGLLVIPKGFSKDLL-KGESATVTVYINSSNLLVSKLILNALQSLLqqlnasa 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 215 ----LYHLNVTETIQIWSTPFFQEITDIVFkielYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWI 290
Cdd:pfam12698 132 lvllLEALSTSAPIPVESTPLFNPQSGYAY----YLVGLILMIIILIGAAIIAVSIVEEKESRIKERLLVSGVSPLQYWL 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 291 GQAVVDIPLFFIILILMLgsLLAFHYGLYFYTvkFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALA 370
Cdd:pfam12698 208 GKILGDFLVGLLQLLIIL--LLLFGIGIPFGN--LGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVILLLSGF 283
|
250 260 270
....*....|....*....|....*....|..
gi 16551961 371 CIAIteitfFMGYTIATILHYAFCiIIPIYPL 402
Cdd:pfam12698 284 FGGL-----FPLEDPPSFLQWIFS-IIPFFSP 309
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
549-690 |
1.39e-08 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 58.35 E-value: 1.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 549 GEILGLLGPNGAGKSTIINILVGDIEPTS--GQVFLGDYSSETSeddgSLKCMGYCPQINPLWPDTTLQEHFeIYGAVKG 626
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPTKQ----ILKRTGFVTQDDILYPHLTVRETL-VFCSLLR 168
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 627 MSASDMKEVISRITHGLDLKEHLQKT---------VKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 690
Cdd:PLN03211 169 LPKSLTKQEKILVAESVISELGLTKCentiignsfIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATA 241
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
542-717 |
1.64e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 58.77 E-value: 1.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVgDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQ------------INPL- 608
Cdd:TIGR01271 1238 LSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGVSWNSVTLQTWRKAFGVIPQkvfifsgtfrknLDPYe 1316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 609 -WPDTTLQEHFEIYGavkgmsasdMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:TIGR01271 1317 qWSDEEIWKVAEEVG---------LKSVIEQFPDKLDFV--LVDGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLD 1385
|
170 180 190
....*....|....*....|....*....|
gi 16551961 688 PKAKQHMWRAIRTAFKNrkRAAILTTHYME 717
Cdd:TIGR01271 1386 PVTLQIIRKTLKQSFSN--CTVILSEHRVE 1413
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
542-756 |
1.80e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 56.68 E-value: 1.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYS----SETSEDDGSLKCMGYCPQI--NPLWPDTTLQ 615
Cdd:PRK13649 26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLitstSKNKDIKQIRKKVGLVFQFpeSQLFEETVLK 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 ------EHFeiygavkGMSASDMKEVISRITHGLDLKEHL-QKTVKKLPAGIKRKLCFA--LSMlgNPQITLLDEPSTGM 686
Cdd:PRK13649 106 dvafgpQNF-------GVSQEEAEALAREKLALVGISESLfEKNPFELSGGQMRRVAIAgiLAM--EPKILVLDEPTAGL 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 687 DPKAKqhmwRAIRTAFKNRKRAA---ILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVqhlKSRFGKGYFLEIK 756
Cdd:PRK13649 177 DPKGR----KELMTLFKKLHQSGmtiVLVTHLMDDVANYADFVYVLEKGKLVLSGKP---KDIFQDVDFLEEK 242
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
540-732 |
2.16e-08 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 57.75 E-value: 2.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDySSETSEDDGSLKCMG-Y-CPQINPLWPDTTLQEH 617
Cdd:PRK15439 28 KGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGG-NPCARLTPAKAHQLGiYlVPQEPLLFPNLSVKEN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FeIYGAVKGM-SASDMKEVISRITHGLDLkehlqktvkKLPAG-----------IKRKLcfalsmLGNPQITLLDEPSTG 685
Cdd:PRK15439 107 I-LFGLPKRQaSMQKMKQLLAALGCQLDL---------DSSAGslevadrqiveILRGL------MRDSRILILDEPTAS 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 16551961 686 MDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG 732
Cdd:PRK15439 171 LTPAETERLFSRIR-ELLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
536-734 |
2.20e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 56.21 E-value: 2.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 536 KVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQ 615
Cdd:PRK14246 23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIDAIKLRKEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEIYGAV----KGMSASDMKEVISRITHGL-------DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPST 684
Cdd:PRK14246 103 PHLSIYDNIayplKSHGIKEKREIKKIVEECLrkvglwkEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 16551961 685 GMDPKAKQHMWRAIrTAFKNrKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK14246 183 MIDIVNSQAIEKLI-TELKN-EIAIVIVSHNPQQVARVADYVAFLYNGEL 230
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
531-735 |
2.37e-08 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 57.53 E-value: 2.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 531 SRKVKKVATkyISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPT-SGQVFLGDYSSETSEDDGSLK---CM------- 599
Cdd:TIGR02633 270 NPHRKRVDD--VSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRNPAQAIRagiAMvpedrkr 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 600 -GYCPQINpLWPDTTLQEhFEIYGAVKGMSASDMKEVISRITHGLDLKE-HLQKTVKKLPAGIKRKLCFALSMLGNPQIT 677
Cdd:TIGR02633 348 hGIVPILG-VGKNITLSV-LKSFCFKMRIDAAAELQIIGSAIQRLKVKTaSPFLPIGRLSGGNQQKAVLAKMLLTNPRVL 425
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 678 LLDEPSTGMDPKAKQHMWRAIrTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:TIGR02633 426 ILDEPTRGVDVGAKYEIYKLI-NQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
513-584 |
2.98e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 57.44 E-value: 2.98e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 513 IMVSNLHKEYDDKkdfLLsrkvkkvaTKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD 584
Cdd:PRK11819 325 IEAENLSKSFGDR---LL--------IDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGE 385
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
513-734 |
3.79e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 55.86 E-value: 3.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKkdflLSRKVKkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgDYSSETSED 592
Cdd:PRK13651 3 IKVKNIVKIFNKK----LPTELK--ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTI---EWIFKDEKN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLKcmgycpQINPLWPDTTLQ--------------------------EHFE-------IYGAVK-GMSASDMKEVISR 638
Cdd:PRK13651 74 KKKTK------EKEKVLEKLVIQktrfkkikkikeirrrvgvvfqfaeyQLFEqtiekdiIFGPVSmGVSKEEAKKRAAK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 639 ITH--GLDLkEHLQKTVKKLPAGIKRKLCFA--LSMlgNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKrAAILTTH 714
Cdd:PRK13651 148 YIElvGLDE-SYLQRSPFELSGGQKRRVALAgiLAM--EPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGK-TIILVTH 223
|
250 260
....*....|....*....|
gi 16551961 715 YMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK13651 224 DLDNVLEWTKRTIFFKDGKI 243
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
542-734 |
3.87e-08 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 55.10 E-value: 3.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTI---INILVgdiEPTSGQVFLGDYSSETSEDDGSL--KCMGYCPQINPLWPDTTLQE 616
Cdd:PRK09493 20 IDLNIDQGEVVVIIGPSGSGKSTLlrcINKLE---EITSGDLIVDGLKVNDPKVDERLirQEAGMVFQQFYLFPHLTALE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFeIYGA--VKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHM 694
Cdd:PRK09493 97 NV-MFGPlrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPELRHEV 175
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 16551961 695 WRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK09493 176 LKVMQD-LAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
538-743 |
6.83e-08 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 56.40 E-value: 6.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVF---------------LGDYS-SETSEDDGSLKCMGY 601
Cdd:PRK10261 31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQcdkmllrrrsrqvieLSEQSaAQMRHVRGADMAMIF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 602 CPQINPLWPDTTLQEhfEIYGAVKGMSASDMKEVISRITHGLDL------KEHLQKTVKKLPAGIKRKLCFALSMLGNPQ 675
Cdd:PRK10261 111 QEPMTSLNPVFTVGE--QIAESIRLHQGASREEAMVEAKRMLDQvripeaQTILSRYPHQLSGGMRQRVMIAMALSCRPA 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 676 ITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:PRK10261 189 VLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
537-727 |
6.83e-08 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 54.79 E-value: 6.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 537 VATKYISFCVKKGEILGLLGPNGAGKSTIINIL--VGDIEPT---SGQVFLGDYSSetseddgslkcmgYCPQINPLWPD 611
Cdd:PRK14243 24 LAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrLNDLIPGfrvEGKVTFHGKNL-------------YAPDVDPVEVR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 612 TTLQEHFE-------------IYGA-VKGMSAsDMKEVISRITHGLDL----KEHLQKTVKKLPAGIKRKLCFALSMLGN 673
Cdd:PRK14243 91 RRIGMVFQkpnpfpksiydniAYGArINGYKG-DMDELVERSLRQAALwdevKDKLKQSGLSLSGGQQQRLCIARAIAVQ 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 674 PQITLLDEPSTGMDPKAKqhmwRAIRTAFKNRKR--AAILTTHYMEEAEAVCDRVA 727
Cdd:PRK14243 170 PEVILMDEPCSALDPIST----LRIEELMHELKEqyTIIIVTHNMQQAARVSDMTA 221
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
542-749 |
7.05e-08 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 56.12 E-value: 7.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEddgSL-KCMGYCPQINPLW--------- 609
Cdd:PRK13657 354 VSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDgtDIRTVTRA---SLrRNIAVVFQDAGLFnrsiednir 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 610 ---PDTTlqeHFEIYGAVKGMSASDMkevISRITHGLDlkehlqkTV-----KKLPAGIKRKLCFALSMLGNPQITLLDE 681
Cdd:PRK13657 431 vgrPDAT---DEEMRAAAERAQAHDF---IERKPDGYD-------TVvgergRQLSGGERQRLAIARALLKDPPILILDE 497
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16551961 682 PSTGMDPKAKQHMWRAIRTAFKNRKRAAI---LTThyMEEAeavcDRVAIMVSGQLRCIGTVQHLKSRFGK 749
Cdd:PRK13657 498 ATSALDVETEAKVKAALDELMKGRTTFIIahrLST--VRNA----DRILVFDNGRVVESGSFDELVARGGR 562
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
547-714 |
8.21e-08 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 56.39 E-value: 8.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 547 KKGEILGLLGPNGAGKSTIINILVGdiEPTSGQVfLGDY--SSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFeIYGAV 624
Cdd:PLN03140 904 RPGVLTALMGVSGAGKTTLMDVLAG--RKTGGYI-EGDIriSGFPKKQETFARISGYCEQNDIHSPQVTVRESL-IYSAF 979
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 ----KGMSASDMKEVISRITHGLDLkEHLQKTVKKLPaGI-------KRKLCFALSMLGNPQITLLDEPSTGMDPKAKQH 693
Cdd:PLN03140 980 lrlpKEVSKEEKMMFVDEVMELVEL-DNLKDAIVGLP-GVtglsteqRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1057
|
170 180
....*....|....*....|.
gi 16551961 694 MWRAIRTAFkNRKRAAILTTH 714
Cdd:PLN03140 1058 VMRTVRNTV-DTGRTVVCTIH 1077
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
552-690 |
1.02e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 55.64 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 552 LGLLGPNGAGKSTIINILVGDIEPTSGQVF------LGDYSSETSED-DGSLKCMGYCPQINPLWPDTTLQEHFEIYGav 624
Cdd:PLN03073 538 IAMVGPNGIGKSTILKLISGELQPSSGTVFrsakvrMAVFSQHHVDGlDLSSNPLLYMMRCFPGVPEQKLRAHLGSFG-- 615
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 625 kgmsasdmkevisrITHGLDLkehlqKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 690
Cdd:PLN03073 616 --------------VTGNLAL-----QPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDA 662
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
546-733 |
1.03e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 55.51 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGD----YSSETSEDDG------SLKCMGYCPQINPLWpdttL 614
Cdd:PRK10982 21 VRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSIlFQGKeidfKSSKEALENGismvhqELNLVLQRSVMDNMW----L 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHfeiygAVKGM--SASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQ 692
Cdd:PRK10982 97 GRY-----PTKGMfvDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVN 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 16551961 693 HMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:PRK10982 172 HLFTIIRK-LKERGCGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
542-733 |
1.30e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 55.22 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGdIEPTsgqvflGDYSSETSEDDGSLKCMGY----------CPQINPLWPD 611
Cdd:TIGR02633 20 IDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPH------GTWDGEIYWSGSPLKASNIrdteragiviIHQELTLVPE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 612 TTLQEHF----EIYGAVKGMSASDMKEVISRITHGLDLKE-HLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGM 686
Cdd:TIGR02633 93 LSVAENIflgnEITLPGGRMAYNAMYLRAKNLLRELQLDAdNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPSSSL 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 16551961 687 DPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQ 733
Cdd:TIGR02633 173 TEKETEILLDIIRD-LKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
515-586 |
1.32e-07 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 54.03 E-value: 1.32e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 515 VSNLHKEYDDKKDFLLSRKVKkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-------GDYS 586
Cdd:PRK15112 7 VRNLSKTFRYRTGWFRRQTVE--AVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIddhplhfGDYS 83
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
515-583 |
1.87e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 54.96 E-value: 1.87e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 515 VSNLHKEYDDK---KDFllsrkvkkvatkyiSFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG 583
Cdd:PRK11147 322 MENVNYQIDGKqlvKDF--------------SAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCG 379
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
515-734 |
2.22e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 53.15 E-value: 2.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYddKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLG-DYSSETSED 592
Cdd:PRK10419 6 VSGLSHHY--AHGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVsWRGePLAKLNRAQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 593 DGSLK---CMGYCPQINPLWPDTTLQEHF-EIYGAVKGMSASDMKEVISRITHGLDLK-EHLQKTVKKLPAGIKRKLCFA 667
Cdd:PRK10419 84 RKAFRrdiQMVFQDSISAVNPRKTVREIIrEPLRHLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 668 LSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:PRK10419 164 RALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQI 230
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
513-585 |
2.28e-07 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 52.78 E-value: 2.28e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 513 IMVSNLHKEYDDKkdfllsrkvkkVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDY 585
Cdd:COG4604 2 IEIKNVSKRYGGK-----------VVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGL 63
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
542-717 |
2.61e-07 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 52.33 E-value: 2.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVF----LGDYSSETSEDDGSLKCMGYCPQiNPLWPDTTLQEH 617
Cdd:cd03290 20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwsnkNESEPSFEATRSRNRYSVAYAAQ-KPWLLNATVEEN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 F--------EIYGAVkgMSASDMKEVISRITHGlDLKEHLQKTVKkLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPK 689
Cdd:cd03290 99 ItfgspfnkQRYKAV--TDACSLQPDIDLLPFG-DQTEIGERGIN-LSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 174
|
170 180
....*....|....*....|....*....
gi 16551961 690 AKQH-MWRAIRTAFKNRKRAAILTTHYME 717
Cdd:cd03290 175 LSDHlMQEGILKFLQDDKRTLVLVTHKLQ 203
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
540-738 |
4.66e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 52.15 E-value: 4.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEptsgqvflgdySSETSEDDGSLKCMG---YCPQINPL-------- 608
Cdd:PRK14267 21 KGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLE-----------LNEEARVEGEVRLFGrniYSPDVDPIevrrevgm 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 609 -------WPDTTLQEHFEIYGAVKGMSASDmKEVISRITHGL-------DLKEHLQKTVKKLPAGIKRKLCFALSMLGNP 674
Cdd:PRK14267 90 vfqypnpFPHLTIYDNVAIGVKLNGLVKSK-KELDERVEWALkkaalwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKP 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 675 QITLLDEPSTGMDPKAKQHMWRAIrtaFKNRKRAAI-LTTHYMEEAEAVCDRVAIMVSGQLRCIG 738
Cdd:PRK14267 169 KILLMDEPTANIDPVGTAKIEELL---FELKKEYTIvLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
542-687 |
5.65e-07 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 51.76 E-value: 5.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGdIEPTSGQVFL-----GDYSSEtseddgSLKCM-GYCPQINPLWPDTTLQ 615
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAG-LLPGQGEILLngrplSDWSAA------ELARHrAYLSQQQSPPFAMPVF 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 616 EHFEIYGAVKGMSASDmKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML-----GNP--QITLLDEPSTGMD 687
Cdd:COG4138 88 QYLALHQPAGASSEAV-EQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPegQLLLLDEPMNSLD 165
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
542-735 |
6.34e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.01 E-value: 6.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIE-PTSGQVFLGD-----------------YSSETSEDDGSLKCMGYCP 603
Cdd:PRK13549 281 VSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGkpvkirnpqqaiaqgiaMVPEDRKRDGIVPVMGVGK 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 604 QInplwpdtTLQ--EHFeiygaVKGMSASDMKEV--ISRITHGLDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQITL 678
Cdd:PRK13549 361 NI-------TLAalDRF-----TGGSRIDDAAELktILESIQRLKVKtASPELAIARLSGGNQQKAVLAKCLLLNPKILI 428
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 679 LDEPSTGMDPKAKQHMWRAIrTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:PRK13549 429 LDEPTRGIDVGAKYEIYKLI-NQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
538-687 |
7.32e-07 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 51.03 E-value: 7.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 538 ATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSEDDGSL-KCMGYCPQINPLWPDTTL 614
Cdd:PRK10908 17 ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSghDITRLKNREVPFLrRQIGMIFQDHHLLMDRTV 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 615 QEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK10908 97 YDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLD 169
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
553-735 |
7.57e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 52.59 E-value: 7.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 553 GLLGPNGAGKSTIINILVGDIEPTSGQVFLgdyssETSEDDGSLK---------------CMGYcpqiNPLWpdTTLQEH 617
Cdd:PRK15064 31 GLIGANGCGKSTFMKILGGDLEPSAGNVSL-----DPNERLGKLRqdqfafeeftvldtvIMGH----TELW--EVKQER 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FEIYgAVKGMSASD-MK----EVI----------SR-----ITHGLDLKEHlQKTVKKLPAGIKRKLCFALSMLGNPQIT 677
Cdd:PRK15064 100 DRIY-ALPEMSEEDgMKvadlEVKfaemdgytaeARagellLGVGIPEEQH-YGLMSEVAPGWKLRVLLAQALFSNPDIL 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 678 LLDEPSTGMDpkakQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLR 735
Cdd:PRK15064 178 LLDEPTNNLD----INTIRWLEDVLNERNSTMIIISHDRHFLNSVCTHMADLDYGELR 231
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
542-687 |
1.92e-06 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 49.93 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGdIEPTSGQVFLGDYSSETSEDDGSLKCMGY-CPQINPLWPDTTLQeHFEI 620
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPLEAWSAAELARHRAYlSQQQTPPFAMPVFQ-YLTL 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 621 YGAVKGMSASDMKeVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSML-----GNP--QITLLDEPSTGMD 687
Cdd:PRK03695 93 HQPDKTRTEAVAS-ALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPagQLLLLDEPMNSLD 165
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
542-739 |
1.98e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 51.47 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGdIEPTsgqvflGDYSSETSEDDGSLKCMGYCpqinplwpDTtlqEHFEI- 620
Cdd:PRK13549 24 VSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPH------GTYEGEIIFEGEELQASNIR--------DT---ERAGIa 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 -----YGAVKGMSASDMKEVISRITHG---------LDLKEHLQKT---------VKKLPAGIKRKLCFALSMLGNPQIT 677
Cdd:PRK13549 86 iihqeLALVKELSVLENIFLGNEITPGgimdydamyLRAQKLLAQLkldinpatpVGNLGLGQQQLVEIAKALNKQARLL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16551961 678 LLDEPSTGMDPKAKQHMWRAIRTaFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGqlRCIGT 739
Cdd:PRK13549 166 ILDEPTASLTESETAVLLDIIRD-LKAHGIACIYISHKLNEVKAISDTICVIRDG--RHIGT 224
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
546-715 |
2.34e-06 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 49.79 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 546 VKKGEILGLLGPNGAGKSTIINILVG--DIEPTSGQV-FLG----DYSSETSEDDGSLKCMGYCPQI----NPLWPDTTL 614
Cdd:PRK09580 24 VRPGEVHAIMGPNGSGKSTLSATLAGreDYEVTGGTVeFKGkdllELSPEDRAGEGIFMAFQYPVEIpgvsNQFFLQTAL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 615 QEHFEiYGAVKGMSASDMKEVISRITHGLDLKEH-LQKTVKKLPAGIKRKLCFALSMLG-NPQITLLDEPSTGMDPKAKQ 692
Cdd:PRK09580 104 NAVRS-YRGQEPLDRFDFQDLMEEKIALLKMPEDlLTRSVNVGFSGGEKKRNDILQMAVlEPELCILDESDSGLDIDALK 182
|
170 180
....*....|....*....|...
gi 16551961 693 HMWRAIrTAFKNRKRAAILTTHY 715
Cdd:PRK09580 183 IVADGV-NSLRDGKRSFIIVTHY 204
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
513-714 |
2.97e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 51.18 E-value: 2.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 513 IMVSNLHKEYDDKKDFLLsrkvkkvaTKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-------- 584
Cdd:PTZ00265 383 IQFKNVRFHYDTRKDVEI--------YKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDshnlkdin 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 585 -------------------------------------YSSETSEDDGS---------LKCMGYCP-QINPLWPDTTLQEH 617
Cdd:PTZ00265 455 lkwwrskigvvsqdpllfsnsiknnikyslyslkdleALSNYYNEDGNdsqenknkrNSCRAKCAgDLNDMSNTTDSNEL 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 618 FEIYGAVKGMSASDMKEVISRI-THGL-----DLKEHL-QKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 690
Cdd:PTZ00265 535 IEMRKNYQTIKDSEVVDVSKKVlIHDFvsalpDKYETLvGSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKS 614
|
250 260
....*....|....*....|....
gi 16551961 691 KQHMWRAIRTAFKNRKRAAILTTH 714
Cdd:PTZ00265 615 EYLVQKTINNLKGNENRITIIIAH 638
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
542-737 |
3.90e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 50.50 E-value: 3.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETS--------------EDDGSLKCMGYCP-QIN 606
Cdd:PRK10982 267 VSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHnaneainhgfalvtEERRSTGIYAYLDiGFN 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 607 PLWpdTTLQEHFEIYGAvkgMSASDMKEVISRITHGLDLKEHLQKT-VKKLPAGIKRKLCFALSMLGNPQITLLDEPSTG 685
Cdd:PRK10982 347 SLI--SNIRNYKNKVGL---LDNSRMKSDTQWVIDSMRVKTPGHRTqIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRG 421
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 16551961 686 MDPKAKQHMWRAIrTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCI 737
Cdd:PRK10982 422 IDVGAKFEIYQLI-AELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGI 472
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
551-740 |
4.83e-06 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 49.49 E-value: 4.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 551 ILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSL----KCMGYCPQINPLWPdttlqeHFEIYGAVK- 625
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLppekRRIGYVFQDARLFP------HYKVRGNLRy 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 626 GMSASdMKEVISRITHGLDLkEHLqktVKKLPA----GIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTA 701
Cdd:PRK11144 100 GMAKS-MVAQFDKIVALLGI-EPL---LDRYPGslsgGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERL 174
|
170 180 190
....*....|....*....|....*....|....*....
gi 16551961 702 FKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTV 740
Cdd:PRK11144 175 AREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
542-742 |
5.94e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 49.91 E-value: 5.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSLKCMGYCPqinplwpdttlqEHFEI 620
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLdGKPIDIRSPRDAIRAGIMLCP------------EDRKA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 621 YGAVKGMSASDMKEVISR---ITHGLDL---------KEHLQKTVKKLPAGikRKLCFALSMlGNPQ------------- 675
Cdd:PRK11288 340 EGIIPVHSVADNINISARrhhLRAGCLInnrweaenaDRFIRSLNIKTPSR--EQLIMNLSG-GNQQkailgrwlsedmk 416
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16551961 676 ITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRciGTVQH 742
Cdd:PRK11288 417 VILLDEPTRGIDVGAKHEIYNVIY-ELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA--GELAR 480
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
542-745 |
6.04e-06 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 48.61 E-value: 6.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLGDYSSETSEDD--GSLKCMGYCPQINPLWPDTT----- 613
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEIlFDGENIPAMSRSRlyTVRKRMSMLFQSGALFTDMNvfdnv 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 ---LQEHfeiygavkgmsaSDMKEVISRITHGLDLKE-HLQKTVKKLPA----GIKRKLCFALSMLGNPQITLLDEPSTG 685
Cdd:PRK11831 106 aypLREH------------TQLPAPLLHSTVMMKLEAvGLRGAAKLMPSelsgGMARRAALARAIALEPDLIMFDEPFVG 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 686 MDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:PRK11831 174 QDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQA 233
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
542-700 |
6.71e-06 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 47.64 E-value: 6.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPT---SGQVFLGDYSSetseDDGSLKCMG---YCPQINPLWPDTTLQ 615
Cdd:cd03233 26 FSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPY----KEFAEKYPGeiiYVSEEDVHFPTLTVR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEIYGAVKGmsaSDMkevisrithgldlkehlqktVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMW 695
Cdd:cd03233 102 ETLDFALRCKG---NEF--------------------VRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEIL 158
|
....*
gi 16551961 696 RAIRT 700
Cdd:cd03233 159 KCIRT 163
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
549-698 |
6.93e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 49.78 E-value: 6.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 549 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVF------LGDYSSETSE----DDGSLKCMGycpQINPLWPDTTLQEHF 618
Cdd:PRK10636 338 GSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGlakgikLGYFAQHQLEflraDESPLQHLA---RLAPQELEQKLRDYL 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGaVKGMSASDMKEVISrithgldlkehlqktvkklpAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAI 698
Cdd:PRK10636 415 GGFG-FQGDKVTEETRRFS--------------------GGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEAL 473
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
542-745 |
8.24e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 49.74 E-value: 8.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYssetseDDGSL------KCMGYCPQINPLWPDTT-- 613
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGC------DISKFglmdlrKVLGIIPQAPVLFSGTVrf 1331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 ----LQEH--FEIYGAvkgMSASDMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:PLN03130 1332 nldpFNEHndADLWES---LERAHLKDVIRRNSLGLDAE--VSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVD 1406
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 688 PKAKQHMWRAIRTAFKNrkrAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:PLN03130 1407 VRTDALIQKTIREEFKS---CTMLIIAHRLNTIIDCDRILVLDAGRVVEFDTPENLLS 1461
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
542-584 |
1.54e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 48.64 E-value: 1.54e-05
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD 584
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDG 393
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
535-687 |
1.86e-05 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 47.29 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQiNPLWP-DTT 613
Cdd:PRK10253 19 KYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQ-NATTPgDIT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 LQE--------HFEIYGAVKgmsaSDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTG 685
Cdd:PRK10253 98 VQElvargrypHQPLFTRWR----KEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTW 173
|
..
gi 16551961 686 MD 687
Cdd:PRK10253 174 LD 175
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
540-745 |
2.15e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 47.16 E-value: 2.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgDYSSETSeddgslkcmgYCPQINPLWPDtTLQEHFe 619
Cdd:cd03291 54 KNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI---KHSGRIS----------FSSQFSWIMPG-TIKENI- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 iygaVKGMSASDMKevISRITHGLDLKEHLQKTVKK-----------LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:cd03291 119 ----IFGVSYDEYR--YKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16551961 689 KAKQHMWRA-IRTAFKNRKRaaILTTHYMEEAEaVCDRVAIMVSGQLRCIGTVQHLKS 745
Cdd:cd03291 193 FTEKEIFEScVCKLMANKTR--ILVTSKMEHLK-KADKILILHEGSSYFYGTFSELQS 247
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
540-746 |
3.18e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.98 E-value: 3.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgDYSSETSeddgslkcmgYCPQINPLWPDtTLQEHFe 619
Cdd:TIGR01271 443 KNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI---KHSGRIS----------FSPQTSWIMPG-TIKDNI- 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 620 iygaVKGMSASDMKevISRITHGLDLKEHLQKTVKK-----------LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDP 688
Cdd:TIGR01271 508 ----IFGLSYDEYR--YTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 689 KAKQHMW-RAIRTAFKNRKRaaILTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSR 746
Cdd:TIGR01271 582 VTEKEIFeSCLCKLMSNKTR--ILVTSKLEHLKKA-DKILLLHEGVCYFYGTFSELQAK 637
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
526-752 |
4.95e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 47.41 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 526 KDFLLSRKVKKVAT-KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPtsgqvFLGDYSSETSEDDGSLKCMG---- 600
Cdd:TIGR00956 63 RKLKKFRDTKTFDIlKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDG-----FHIGVEGVITYDGITPEEIKkhyr 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 601 ----YCPQINPLWPDTTLQEHFEIYGA-------VKGMS----ASDMKEVISRiTHGLDlkeHLQKT------VKKLPAG 659
Cdd:TIGR00956 138 gdvvYNAETDVHFPHLTVGETLDFAARcktpqnrPDGVSreeyAKHIADVYMA-TYGLS---HTRNTkvgndfVRGVSGG 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 660 IKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAfKNRKRAAILTTHYM--EEAEAVCDRVAIMVSGQLRCI 737
Cdd:TIGR00956 214 ERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTS-ANILDTTPLVAIYQcsQDAYELFDKVIVLYEGYQIYF 292
|
250
....*....|....*.
gi 16551961 738 GTVQHLKSRFGK-GYF 752
Cdd:TIGR00956 293 GPADKAKQYFEKmGFK 308
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
542-699 |
6.43e-05 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 46.67 E-value: 6.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILvGDIEPTSGQVFlgdysseTSEDDGSlkcMGYCPQiNPLWPDTTLQEHFeIY 621
Cdd:TIGR00954 471 LSFEVPSGNNLLICGPNGCGKSSLFRIL-GELWPVYGGRL-------TKPAKGK---LFYVPQ-RPYMTLGTLRDQI-IY 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 622 G------AVKGMSASDMKEVISRITHGLDLKEH-----LQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 690
Cdd:TIGR00954 538 PdssedmKRRGLSDKDLEQILDNVQLTHILEREggwsaVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDV 617
|
....*....
gi 16551961 691 KQHMWRAIR 699
Cdd:TIGR00954 618 EGYMYRLCR 626
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
540-714 |
7.33e-05 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 46.26 E-value: 7.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKC----MGYCPQINPLWPDTTLQ 615
Cdd:PRK10535 25 KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQLrrehFGFIFQRYHLLSHLTAA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 616 EHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMw 695
Cdd:PRK10535 105 QNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEV- 183
|
170
....*....|....*....
gi 16551961 696 RAIRTAFKNRKRAAILTTH 714
Cdd:PRK10535 184 MAILHQLRDRGHTVIIVTH 202
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
507-580 |
1.16e-04 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 44.92 E-value: 1.16e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16551961 507 CEEKPSIMVSNLHKEYDDKKDFllsRKVkkvatkyiSFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV 580
Cdd:PRK11701 1 MMDQPLLSVRGLTKLYGPRKGC---RDV--------SFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEV 63
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
532-714 |
1.52e-04 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 45.48 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 532 RKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIepTSGQVFLGDYSSETSEDDGSL-KCMGYCPQINPLWP 610
Cdd:TIGR00956 772 KKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERV--TTGVITGGDRLVNGRPLDSSFqRSIGYVQQQDLHLP 849
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 611 DTTLQEHFeIYGAV----KGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGI----KRKLCFALSMLGNPQITL-LDE 681
Cdd:TIGR00956 850 TSTVRESL-RFSAYlrqpKSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGLnveqRKRLTIGVELVAKPKLLLfLDE 928
|
170 180 190
....*....|....*....|....*....|....*
gi 16551961 682 PSTGMDpkaKQHMWRAIRTAFK--NRKRAAILTTH 714
Cdd:TIGR00956 929 PTSGLD---SQTAWSICKLMRKlaDHGQAILCTIH 960
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
548-584 |
1.53e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 42.75 E-value: 1.53e-04
10 20 30
....*....|....*....|....*....|....*..
gi 16551961 548 KGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGD 584
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYID 37
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
511-564 |
1.95e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 45.08 E-value: 1.95e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 16551961 511 PSIMVSNLHKEYDDKKDfLLSRKV-KKVATKYISFCVKKGEILGLLGPNGAGKST 564
Cdd:PRK15134 274 PLLDVEQLQVAFPIRKG-ILKRTVdHNVVVKNISFTLRPGETLGLVGESGSGKST 327
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
515-583 |
2.51e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 44.68 E-value: 2.51e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 515 VSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGdIEPTSGQV-FLG 583
Cdd:COG4172 278 ARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLR-LIPSEGEIrFDG 346
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
542-582 |
3.40e-04 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 44.19 E-value: 3.40e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL 582
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILL 382
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
535-687 |
8.68e-04 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 43.00 E-value: 8.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 535 KKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDyssetseddgSLKCmGYCPQINPLWPDTT- 613
Cdd:TIGR03719 17 KKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQP----------GIKV-GYLPQEPQLDPTKTv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 614 --------------LQEHFEIYGAVKGMSA------SDMKEVISRITH--GLDLKEHLQKT------------VKKLPAG 659
Cdd:TIGR03719 86 renveegvaeikdaLDRFNEISAKYAEPDAdfdklaAEQAELQEIIDAadAWDLDSQLEIAmdalrcppwdadVTKLSGG 165
|
170 180 190
....*....|....*....|....*....|
gi 16551961 660 IKRK--LCFALsmLGNPQITLLDEPSTGMD 687
Cdd:TIGR03719 166 ERRRvaLCRLL--LSKPDMLLLDEPTNHLD 193
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
548-720 |
1.31e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 40.42 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 548 KGEILGLLGPNGAGKSTIINILvgdieptsGQVFLGDYSSETSEDDGSLKCmgYCPQInplwpdttlqeHFEIYGAVKGM 627
Cdd:cd03227 20 EGSLTIITGPNGSGKSTILDAI--------GLALGGAQSATRRRSGVKAGC--IVAAV-----------SAELIFTRLQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 628 SASdMKEVISRITHgldlkehlqktvkklpagikrklcFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKR 707
Cdd:cd03227 79 SGG-EKELSALALI------------------------LALASLKPRPLYILDEIDRGLDPRDGQALAEAIL-EHLVKGA 132
|
170
....*....|...
gi 16551961 708 AAILTTHYMEEAE 720
Cdd:cd03227 133 QVIVITHLPELAE 145
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
508-583 |
1.47e-03 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 41.62 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 508 EEKPSIM-VSNLHKEYD--DKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQV-FLG 583
Cdd:PRK15079 3 EGKKVLLeVADLKVHFDikDGKQWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVaWLG 82
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
553-682 |
1.47e-03 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 42.03 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 553 GLLGPNGAGKSTIINILVGDIEPTSGQVFLGD-YSsetseddgslkcMGYCPQINPLWPDTT---------------LQE 616
Cdd:PRK11819 37 GVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPgIK------------VGYLPQEPQLDPEKTvrenveegvaevkaaLDR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 HFEIYGAvkgMSASD---------MKEVISRITH--GLDLKEHLQ------------KTVKKLPAGIKRK--LCFALsmL 671
Cdd:PRK11819 105 FNEIYAA---YAEPDadfdalaaeQGELQEIIDAadAWDLDSQLEiamdalrcppwdAKVTKLSGGERRRvaLCRLL--L 179
|
170
....*....|.
gi 16551961 672 GNPQITLLDEP 682
Cdd:PRK11819 180 EKPDMLLLDEP 190
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
625-743 |
1.53e-03 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 41.63 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 625 KGMSASDMKEVISRITHGLDLKEhLQKTVKKLP----AGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHmwraIRT 700
Cdd:PRK09473 128 KGMSKAEAFEESVRMLDAVKMPE-ARKRMKMYPhefsGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQ----IMT 202
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 16551961 701 AFKNRKR----AAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 743
Cdd:PRK09473 203 LLNELKRefntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
542-571 |
1.54e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 42.08 E-value: 1.54e-03
10 20 30
....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVG 571
Cdd:NF040905 20 VNLSVREGEIHALCGENGAGKSTLMKVLSG 49
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
542-734 |
1.71e-03 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 41.94 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLG--DYSSETSE---DDGslkcMGYCPQiNPLWpdttlqe 616
Cdd:COG3845 277 VSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDgeDITGLSPRerrRLG----VAYIPE-DRLG------- 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 617 hfeiYGAVKGMSASD-------MKEVISRitHGL----DLKEHLQKTVKKL---PAGIKR-----------KLCFALSML 671
Cdd:COG3845 345 ----RGLVPDMSVAEnlilgryRRPPFSR--GGFldrkAIRAFAEELIEEFdvrTPGPDTparslsggnqqKVILARELS 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16551961 672 GNPQITLLDEPSTGMDPKAKQHMWRAIRTAfKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQL 734
Cdd:COG3845 419 RDPKLLIAAQPTRGLDVGAIEFIHQRLLEL-RDAGAAVLLISEDLDEILALSDRIAVMYEGRI 480
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
517-687 |
1.97e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 41.10 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 517 NLHKEYDDKKDFLL-SRKVKkvATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLgDYSSETSEDDGS 595
Cdd:PRK11308 10 DLKKHYPVKRGLFKpERLVK--ALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYY-QGQDLLKADPEA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 596 LKCMGYCPQI---NP---LWP----DTTLQEHFEIYGAvkgMSASDMKEVISRITHGLDLK-EHLQKTVKKLPAGIKRKL 664
Cdd:PRK11308 87 QKLLRQKIQIvfqNPygsLNPrkkvGQILEEPLLINTS---LSAAERREKALAMMAKVGLRpEHYDRYPHMFSGGQRQRI 163
|
170 180
....*....|....*....|...
gi 16551961 665 CFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK11308 164 AIARALMLDPDVVVADEPVSALD 186
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
542-582 |
2.20e-03 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 41.73 E-value: 2.20e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 16551961 542 ISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL 582
Cdd:COG5265 377 VSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILI 417
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
556-687 |
2.68e-03 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 39.85 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 556 GPNGAGKSTIINILVGDIEPTSGQVFlgdYSSETSEDDGSLKCmGYCPQINPLWPDTTLQEHF----EIYGAVkgmsasd 631
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIY---YKNCNINNIAKPYC-TYIGHNLGLKLEMTVFENLkfwsEIYNSA------- 101
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 16551961 632 mkEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMD 687
Cdd:PRK13541 102 --ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLS 155
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
659-714 |
4.28e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 40.07 E-value: 4.28e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 16551961 659 GIKRKLCFALSML---GNPQITLLDEPSTGMDPKAKQHMWRAIRtAFKNRKRAAILTTH 714
Cdd:pfam13304 240 GTKRLLALLAALLsalPKGGLLLIDEPESGLHPKLLRRLLELLK-ELSRNGAQLILTTH 297
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
540-704 |
5.42e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 40.70 E-value: 5.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 540 KYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFL-GDYSSETSEDDGSLKcMGYCPQiNPLWPDTTLQEHF 618
Cdd:TIGR00957 1303 RHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIdGLNIAKIGLHDLRFK-ITIIPQ-DPVLFSGSLRMNL 1380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16551961 619 EIYGAVK------GMSASDMKEVISRITHGLDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQ 692
Cdd:TIGR00957 1381 DPFSQYSdeevwwALELAHLKTFVSALPDKLDHE--CAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDN 1458
|
170
....*....|..
gi 16551961 693 HMWRAIRTAFKN 704
Cdd:TIGR00957 1459 LIQSTIRTQFED 1470
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
548-594 |
6.00e-03 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 38.92 E-value: 6.00e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 16551961 548 KGEILGLLGPNGAGKSTIINILVGDIEPTSGQVflgdyssetSEDDG 594
Cdd:cd01854 84 KGKTSVLVGQSGVGKSTLLNALLPELVLATGEI---------SEKLG 121
|
|
| |
