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Conserved domains on  [gi|1655159022|ref|WP_137642933|]
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type I methionyl aminopeptidase [Lactiplantibacillus modestisalitolerans]

Protein Classification

type I methionyl aminopeptidase( domain architecture ID 10000257)

type I methionyl aminopeptidase (M24A family metallopeptidase) catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides

CATH:  3.90.230.10
EC:  3.4.11.18
Gene Ontology:  GO:0070006|GO:0046914|GO:0006508|GO:0004239
MEROPS:  M24
PubMed:  7674922

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Map COG0024
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
2-254 6.79e-138

Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 439795 [Multi-domain]  Cd Length: 250  Bit Score: 387.82  E-value: 6.79e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:COG0024     1 IEIKTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLELDRIAEEFIRDHGAIPAFLGYYGFPKSICTSVNEVVVHGIPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:COG0024    81 DRVL-KDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESN-GY 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:COG0024   159 SVVREFVGHGIGREMHEEPQVPNYGRPGRGPRLKPGMVLAIEPMINAGTPEV-KVLDDGWTVVTKDGSLSAQFEHTVAVT 237

                         250
                  ....*....|...
gi 1655159022 242 DDGPKILSSFDNE 254
Cdd:COG0024   238 EDGPEILTLPDGG 250
 
Name Accession Description Interval E-value
Map COG0024
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
2-254 6.79e-138

Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 439795 [Multi-domain]  Cd Length: 250  Bit Score: 387.82  E-value: 6.79e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:COG0024     1 IEIKTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLELDRIAEEFIRDHGAIPAFLGYYGFPKSICTSVNEVVVHGIPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:COG0024    81 DRVL-KDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESN-GY 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:COG0024   159 SVVREFVGHGIGREMHEEPQVPNYGRPGRGPRLKPGMVLAIEPMINAGTPEV-KVLDDGWTVVTKDGSLSAQFEHTVAVT 237

                         250
                  ....*....|...
gi 1655159022 242 DDGPKILSSFDNE 254
Cdd:COG0024   238 EDGPEILTLPDGG 250
PRK05716 PRK05716
methionine aminopeptidase; Validated
 1-254 2.14e-123

methionine aminopeptidase; Validated


Pssm-ID: 235576 [Multi-domain]  Cd Length: 252  Bit Score: 351.36  E-value: 2.14e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   1 MITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCP 80
Cdd:PRK05716    2 AITIKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVTTKELDRIAEEYIRDQGAIPAPLGYHGFPKSICTSVNEVVCHGIP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  81 SKDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmG 160
Cdd:PRK05716   82 SDKVL-KEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAIQKYAEAE-G 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 161 YGVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVV 240
Cdd:PRK05716  160 FSVVREYCGHGIGRKFHEEPQIPHYGAPGDGPVLKEGMVFTIEPMINAGKREV-KTLKDGWTVVTKDGSLSAQYEHTVAV 238

                         250
                  ....*....|....
gi 1655159022 241 TDDGPKILSSFDNE 254
Cdd:PRK05716  239 TEDGPEILTLRPEE 252
MetAP1 cd01086
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ...
 10-250 3.84e-116

Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.


Pssm-ID: 238519 [Multi-domain]  Cd Length: 238  Bit Score: 332.54  E-value: 3.84e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  10 IKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPSKDILvKDG 89
Cdd:cd01086     1 IEGMREAGRIVAEVLDELAKAIKPGVTTKELDQIAHEFIEEHGAYPAPLGYYGFPKSICTSVNEVVCHGIPDDRVL-KDG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  90 DLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGYGVVREYIG 169
Cdd:cd01086    80 DIVNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKN-GYSVVREFGG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 170 HGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVTDDGPKILS 249
Cdd:cd01086   159 HGIGRKFHEEPQIPNYGRPGTGPKLKPGMVFTIEPMINLGTYEV-VTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILT 237


                  .
gi 1655159022 250 S 250
Cdd:cd01086   238 L 238
met_pdase_I TIGR00500
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ...
 2-249 6.97e-99

methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]


Pssm-ID: 129591 [Multi-domain]  Cd Length: 247  Bit Score: 289.25  E-value: 6.97e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:TIGR00500   1 ISLKSPDEIEKIRKAGRLAAEVLEELEREVKPGVSTKELDRIAKDFIEKHGAKPAFLGYYGFPGSVCISVNEVVIHGIPD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:TIGR00500  81 KKVL-KDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPGNRIGEIGAAIQKYAEAK-GF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSGETAdDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:TIGR00500 159 SVVREYCGHGIGRKFHEEPQIPNYGKKFTNVRLKEGMVFTIEPMVNTGTEEITTAA-DGWTVKTKDGSLSAQFEHTIVIT 237


                  ....*...
gi 1655159022 242 DDGPKILS 249
Cdd:TIGR00500 238 DNGPEILT 245
Peptidase_M24 pfam00557
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ...
 11-242 4.47e-49

Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.


Pssm-ID: 459852 [Multi-domain]  Cd Length: 208  Bit Score: 160.87  E-value: 4.47e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  11 KGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHdatpGELNFEGYKYSTCVSVNDMICHGCPSKDILvKDGD 90
Cdd:pfam00557   1 ELMRKAARIAAAALEAALAAIRPGVTERELAAELEAARLRR----GGARGPAFPPIVASGPNAAIPHYIPNDRVL-KPGD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  91 LLKVDTVINY-HGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnEMGYG-VVREYI 168
Cdd:pfam00557  76 LVLIDVGAEYdGGYCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLE-EAGLGeYFPHGL 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1655159022 169 GHGIGPTMHEKPDVPHygeAGHGTRLKAGMTITIEPMVNIgdwrsgetaddgwtvrtLDGSLSCQYEHTLVVTD 242
Cdd:pfam00557 155 GHGIGLEVHEGPYISR---GGDDRVLEPGMVFTIEPGIYF-----------------IPGWGGVRIEDTVLVTE 208
 
Name Accession Description Interval E-value
Map COG0024
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
2-254 6.79e-138

Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];


Pssm-ID: 439795 [Multi-domain]  Cd Length: 250  Bit Score: 387.82  E-value: 6.79e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:COG0024     1 IEIKTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLELDRIAEEFIRDHGAIPAFLGYYGFPKSICTSVNEVVVHGIPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:COG0024    81 DRVL-KDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESN-GY 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:COG0024   159 SVVREFVGHGIGREMHEEPQVPNYGRPGRGPRLKPGMVLAIEPMINAGTPEV-KVLDDGWTVVTKDGSLSAQFEHTVAVT 237

                         250
                  ....*....|...
gi 1655159022 242 DDGPKILSSFDNE 254
Cdd:COG0024   238 EDGPEILTLPDGG 250
PRK05716 PRK05716
methionine aminopeptidase; Validated
 1-254 2.14e-123

methionine aminopeptidase; Validated


Pssm-ID: 235576 [Multi-domain]  Cd Length: 252  Bit Score: 351.36  E-value: 2.14e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   1 MITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCP 80
Cdd:PRK05716    2 AITIKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVTTKELDRIAEEYIRDQGAIPAPLGYHGFPKSICTSVNEVVCHGIP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  81 SKDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmG 160
Cdd:PRK05716   82 SDKVL-KEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAIQKYAEAE-G 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 161 YGVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVV 240
Cdd:PRK05716  160 FSVVREYCGHGIGRKFHEEPQIPHYGAPGDGPVLKEGMVFTIEPMINAGKREV-KTLKDGWTVVTKDGSLSAQYEHTVAV 238

                         250
                  ....*....|....
gi 1655159022 241 TDDGPKILSSFDNE 254
Cdd:PRK05716  239 TEDGPEILTLRPEE 252
MetAP1 cd01086
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ...
 10-250 3.84e-116

Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.


Pssm-ID: 238519 [Multi-domain]  Cd Length: 238  Bit Score: 332.54  E-value: 3.84e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  10 IKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPSKDILvKDG 89
Cdd:cd01086     1 IEGMREAGRIVAEVLDELAKAIKPGVTTKELDQIAHEFIEEHGAYPAPLGYYGFPKSICTSVNEVVCHGIPDDRVL-KDG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  90 DLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGYGVVREYIG 169
Cdd:cd01086    80 DIVNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKN-GYSVVREFGG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 170 HGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVTDDGPKILS 249
Cdd:cd01086   159 HGIGRKFHEEPQIPNYGRPGTGPKLKPGMVFTIEPMINLGTYEV-VTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILT 237


                  .
gi 1655159022 250 S 250
Cdd:cd01086   238 L 238
met_pdase_I TIGR00500
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ...
 2-249 6.97e-99

methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]


Pssm-ID: 129591 [Multi-domain]  Cd Length: 247  Bit Score: 289.25  E-value: 6.97e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:TIGR00500   1 ISLKSPDEIEKIRKAGRLAAEVLEELEREVKPGVSTKELDRIAKDFIEKHGAKPAFLGYYGFPGSVCISVNEVVIHGIPD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:TIGR00500  81 KKVL-KDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPGNRIGEIGAAIQKYAEAK-GF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSGETAdDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:TIGR00500 159 SVVREYCGHGIGRKFHEEPQIPNYGKKFTNVRLKEGMVFTIEPMVNTGTEEITTAA-DGWTVKTKDGSLSAQFEHTIVIT 237


                  ....*...
gi 1655159022 242 DDGPKILS 249
Cdd:TIGR00500 238 DNGPEILT 245
PRK07281 PRK07281
methionyl aminopeptidase;
1-250 5.63e-98

methionyl aminopeptidase;


Pssm-ID: 180918  Cd Length: 286  Bit Score: 288.28  E-value: 5.63e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   1 MITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEG----YKYSTCVSVNDMIC 76
Cdd:PRK07281    1 MITLKSAREIEAMDRAGDFLASIHIGLRDLIKPGVDMWEVEEYVRRRCKEENVLPLQIGVDGammdYPYATCCGLNDEVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  77 HGCPSKDILvKDGDLLKVDTVI---------------------------NYHGYLSDSCHAFVAGTPSPEVQKLMDVTLK 129
Cdd:PRK07281   81 HAFPRHYIL-KEGDLLKVDMVLsepldksivdvsklnfdnveqmkkyteSYRGGLADSCWAYAVGTPSDEVKNLMDVTKE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 130 ALYLGIDQAVVGNRIGDIGWAIQNYAENEmGYGVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIG 209
Cdd:PRK07281  160 AMYRGIEQAVVGNRIGDIGAAIQEYAESR-GYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLREGMVLTIEPMINTG 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1655159022 210 DWRSGETADDGWTVRTLDGSLSCQYEHTLVVTDDGPKILSS 250
Cdd:PRK07281  239 TWEIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTS 279
PRK12896 PRK12896
methionine aminopeptidase; Reviewed
 2-248 2.59e-94

methionine aminopeptidase; Reviewed


Pssm-ID: 237252 [Multi-domain]  Cd Length: 255  Bit Score: 277.87  E-value: 2.59e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGelnFEGYK---YSTCVSVNDMICHG 78
Cdd:PRK12896    8 MEIKSPRELEKMRKIGRIVATALKEMGKAVEPGMTTKELDRIAEKRLEEHGAIPS---PEGYYgfpGSTCISVNEEVAHG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  79 CPSKDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnE 158
Cdd:PRK12896   85 IPGPRVI-KDGDLVNIDVSAYLDGYHGDTGITFAVGPVSEEAEKLCRVAEEALWAGIKQVKAGRPLNDIGRAIEDFAK-K 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 159 MGYGVVREYIGHGIGPTMHEKPDV-PHYGEAGHGTRLKAGMTITIEPMVNIGDwRSGETADDGWTVRTLDGSLSCQYEHT 237
Cdd:PRK12896  163 NGYSVVRDLTGHGVGRSLHEEPSViLTYTDPLPNRLLRPGMTLAVEPFLNLGA-KDAETLDDGWTVVTPDKSLSAQFEHT 241

                         250
                  ....*....|.
gi 1655159022 238 LVVTDDGPKIL 248
Cdd:PRK12896  242 VVVTRDGPEIL 252
PRK12897 PRK12897
type I methionyl aminopeptidase;
1-251 1.22e-84

type I methionyl aminopeptidase;


Pssm-ID: 171806  Cd Length: 248  Bit Score: 253.03  E-value: 1.22e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   1 MITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCP 80
Cdd:PRK12897    1 MITIKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKEINTFVEAYLEKHGATSEQKGYNGYPYAICASVNDEMCHAFP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  81 SkDILVKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmG 160
Cdd:PRK12897   81 A-DVPLTEGDIVTIDMVVNLNGGLSDSAWTYRVGKVSDEAEKLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANE-G 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 161 YGVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGdWRSGETADDGWTVRTLDGSLSCQYEHTLVV 240
Cdd:PRK12897  159 FSVARDFTGHGIGKEIHEEPAIFHFGKQGQGPELQEGMVITIEPIVNVG-MRYSKVDLNGWTARTMDGKLSAQYEHTIAI 237

                         250
                  ....*....|.
gi 1655159022 241 TDDGPKILSSF 251
Cdd:PRK12897  238 TKDGPIILTKL 248
PLN03158 PLN03158
methionine aminopeptidase; Provisional
 2-250 7.53e-53

methionine aminopeptidase; Provisional


Pssm-ID: 215607 [Multi-domain]  Cd Length: 396  Bit Score: 176.18  E-value: 7.53e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYKYSTCVSVNDMICHGCPS 81
Cdd:PLN03158  135 VEIKTPEQIQRMRETCRIAREVLDAAARAIKPGVTTDEIDRVVHEATIAAGGYPSPLNYHFFPKSCCTSVNEVICHGIPD 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  82 KDILvKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEmGY 161
Cdd:PLN03158  215 ARKL-EDGDIVNVDVTVYYKGCHGDLNETFFVGNVDEASRQLVKCTYECLEKAIAIVKPGVRYREVGEVINRHATMS-GL 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 162 GVVREYIGHGIGPTMHEKPDVPHYGEAGHGTRLKAGMTITIEPMVNIGDWRSgETADDGWTVRTLDGSLSCQYEHTLVVT 241
Cdd:PLN03158  293 SVVKSYCGHGIGELFHCAPNIPHYARNKAVGVMKAGQVFTIEPMINAGVWRD-RMWPDGWTAVTADGKRSAQFEHTLLVT 371


                  ....*....
gi 1655159022 242 DDGPKILSS 250
Cdd:PLN03158  372 ETGVEVLTA 380
PRK12318 PRK12318
methionyl aminopeptidase;
2-253 9.66e-51

methionyl aminopeptidase;


Pssm-ID: 183434 [Multi-domain]  Cd Length: 291  Bit Score: 167.69  E-value: 9.66e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   2 ITLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEG--YKYSTCVSVNDMICHGC 79
Cdd:PRK12318   41 IIIKTPEQIEKIRKACQVTARILDALCEAAKEGVTTNELDELSRELHKEYNAIPAPLNYGSppFPKTICTSLNEVICHGI 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  80 PSkDILVKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENEm 159
Cdd:PRK12318  121 PN-DIPLKNGDIMNIDVSCIVDGYYGDCSRMVMIGEVSEIKKKVCQASLECLNAAIAILKPGIPLYEIGEVIENCADKY- 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 160 GYGVVREYIGHGIGPTMHEKPDVPHYGEAGHgTRLKAGMTITIEPMVNIGDWRSGETADDGWTVRTLDGSLSCQYEHTLV 239
Cdd:PRK12318  199 GFSVVDQFVGHGVGIKFHENPYVPHHRNSSK-IPLAPGMIFTIEPMINVGKKEGVIDPINHWEARTCDNQPSAQWEHTIL 277

                         250
                  ....*....|....
gi 1655159022 240 VTDDGPKILSSFDN 253
Cdd:PRK12318  278 ITETGYEILTLLDK 291
Peptidase_M24 pfam00557
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ...
 11-242 4.47e-49

Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.


Pssm-ID: 459852 [Multi-domain]  Cd Length: 208  Bit Score: 160.87  E-value: 4.47e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  11 KGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHdatpGELNFEGYKYSTCVSVNDMICHGCPSKDILvKDGD 90
Cdd:pfam00557   1 ELMRKAARIAAAALEAALAAIRPGVTERELAAELEAARLRR----GGARGPAFPPIVASGPNAAIPHYIPNDRVL-KPGD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  91 LLKVDTVINY-HGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnEMGYG-VVREYI 168
Cdd:pfam00557  76 LVLIDVGAEYdGGYCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLE-EAGLGeYFPHGL 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1655159022 169 GHGIGPTMHEKPDVPHygeAGHGTRLKAGMTITIEPMVNIgdwrsgetaddgwtvrtLDGSLSCQYEHTLVVTD 242
Cdd:pfam00557 155 GHGIGLEVHEGPYISR---GGDDRVLEPGMVFTIEPGIYF-----------------IPGWGGVRIEDTVLVTE 208
PepP COG0006
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
5-256 2.04e-35

Xaa-Pro aminopeptidase [Amino acid transport and metabolism];


Pssm-ID: 439777 [Multi-domain]  Cd Length: 299  Bit Score: 128.01  E-value: 2.04e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   5 KSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDAtpgelnfEGYKYSTCVSVND--MICHGCPSk 82
Cdd:COG0006    74 KSPEEIELMRKAARIADAAHEAALAALRPGVTEREVAAELEAAMRRRGA-------EGPSFDTIVASGEnaAIPHYTPT- 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  83 DILVKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnEMGYG 162
Cdd:COG0006   146 DRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAALKPGVTGGEVDAAARDVLA-EAGYG 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 163 vvREYI---GHGIGPTMHEKPDVphygEAGHGTRLKAGMTITIEPMVnigdWRSGEtaddgWTVRTldgslscqyEHTLV 239
Cdd:COG0006   225 --EYFPhgtGHGVGLDVHEGPQI----SPGNDRPLEPGMVFTIEPGI----YIPGI-----GGVRI---------EDTVL 280

                         250
                  ....*....|....*..
gi 1655159022 240 VTDDGPKILSSFDNEFD 256
Cdd:COG0006   281 VTEDGAEVLTRLPRELL 297
APP_MetAP cd01066
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ...
 10-245 2.38e-34

A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.


Pssm-ID: 238514 [Multi-domain]  Cd Length: 207  Bit Score: 122.95  E-value: 2.38e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  10 IKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGElnfegykySTCVSVN--DMICHGCPSKDILvK 87
Cdd:cd01066     1 IARLRKAAEIAEAAMAAAAEAIRPGVTEAEVAAAIEQALRAAGGYPAG--------PTIVGSGarTALPHYRPDDRRL-Q 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  88 DGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnEMGYGVVR-E 166
Cdd:cd01066    72 EGDLVLVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALRPGVTAEEVDAAAREVLE-EHGLGPNFgH 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1655159022 167 YIGHGIGPTMHEKPdvphYGEAGHGTRLKAGMTITIEPMVNIgdwrsgetaddgwtvrtlDGSLSCQYEHTLVVTDDGP 245
Cdd:cd01066   151 RTGHGIGLEIHEPP----VLKAGDDTVLEPGMVFAVEPGLYL------------------PGGGGVRIEDTVLVTEDGP 207
APP-like cd01092
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ...
 10-245 1.05e-25

Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.


Pssm-ID: 238525 [Multi-domain]  Cd Length: 208  Bit Score: 100.28  E-value: 1.05e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  10 IKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDAtpgelnfEGYKYSTCVS--VNDMICHGCPSKDILvK 87
Cdd:cd01092     1 IELLRKAARIADKAFEELLEFIKPGMTEREVAAELEYFMRKLGA-------EGPSFDTIVAsgPNSALPHGVPSDRKI-E 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  88 DGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAEnEMGYGvvrEY 167
Cdd:cd01092    73 EGDLVLIDFGAIYDGYCSDITRTVAVGEPSDELKEIYEIVLEAQQAAIKAVKPGVTAKEVDKAARDVIE-EAGYG---EY 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 168 ----IGHGIGPTMHEKPDVPHYGEaghgTRLKAGMTITIEPMVNIGDWrsgetaddgWTVRTldgslscqyEHTLVVTDD 243
Cdd:cd01092   149 fihrTGHGVGLEVHEAPYISPGSD----DVLEEGMVFTIEPGIYIPGK---------GGVRI---------EDDVLVTED 206


                  ..
gi 1655159022 244 GP 245
Cdd:cd01092   207 GC 208
MetAP2 cd01088
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ...
 28-222 4.09e-21

Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.


Pssm-ID: 238521 [Multi-domain]  Cd Length: 291  Bit Score: 90.00  E-value: 4.09e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  28 EDYIKPGITTWDVDHFAYNYITAHDATPGelnfegykYSTCVSVNDMICHGCPSK--DILVKDGDLLKVDTVINYHGYLS 105
Cdd:cd01088    19 QSLIKPGMTLLEIAEFVENRIRELGAGPA--------FPVNLSINECAAHYTPNAgdDTVLKEGDVVKLDFGAHVDGYIA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 106 DSchAFVAgTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDIGWAIQNYAENemgYGV--VREYIGHGIGP-TMHEKPDV 182
Cdd:cd01088    91 DS--AFTV-DFDPKYDDLLEAAKEALNAAIKEAGPDVRLGEIGEAIEEVIES---YGFkpIRNLTGHSIERyRLHAGKSI 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1655159022 183 PHYGEaGHGTRLKAGMTITIEPMVNIGDwrsGETADDGWT 222
Cdd:cd01088   165 PNVKG-GEGTRLEEGDVYAIEPFATTGK---GYVHDGPEC 200
PA2G4-like cd01089
Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family ...
 14-156 4.05e-10

Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family members have been implicated in cell cycle control.


Pssm-ID: 238522  Cd Length: 228  Bit Score: 58.11  E-value: 4.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  14 QAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDAT--PGELNFE-GYKYSTCVSVNDMICHGCPSK---DILVK 87
Cdd:cd01089     5 KTAGQIANKVLKQVISLCVPGAKVVDLCEKGDKLILEELGKvyKKEKKLEkGIAFPTCISVNNCVCHFSPLKsdaTYTLK 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1655159022  88 DGDLLKVDTVINYHGYLSDSCHAFVAGTPSPEVQ--KLMDVtLKALYLGIDQAV----VGNRIGDIGWAIQNYAE 156
Cdd:cd01089    85 DGDVVKIDLGCHIDGYIAVVAHTIVVGAEAETPVtgKKADV-IAAAHYALEAALrllrPGNQNSDITEAIQKVIV 158
Prolidase cd01087
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ...
 13-250 4.57e-10

Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.


Pssm-ID: 238520 [Multi-domain]  Cd Length: 243  Bit Score: 58.35  E-value: 4.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  13 MQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGelnfegYKYSTCVSVNDMICHGCPSKDILvKDGDLL 92
Cdd:cd01087     4 MRKACDISAEAHRAAMKASRPGMSEYELEAEFEYEFRSRGARLA------YSYIVAAGSNAAILHYVHNDQPL-KDGDLV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  93 KVDTVINYHGYLSDSCHAF-VAGTPSPEVQKLMDVTLKALYLGIDQAVVGNRIGDI-------------GWAI-QNYAEN 157
Cdd:cd01087    77 LIDAGAEYGGYASDITRTFpVNGKFTDEQRELYEAVLAAQKAAIAACKPGVSYEDIhllahrvlaeglkELGIlKGDVDE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022 158 EMGYGVVREY----IGHGIGPTMHekpDVPHYGEAGHGTR-LKAGMTITIEPMV-NIGDWRSGETADDGWTVRTldgsls 231
Cdd:cd01087   157 IVESGAYAKFfphgLGHYLGLDVH---DVGGYLRYLRRARpLEPGMVITIEPGIyFIPDLLDVPEYFRGGGIRI------ 227

                         250
                  ....*....|....*....
gi 1655159022 232 cqyEHTLVVTDDGPKILSS 250
Cdd:cd01087   228 ---EDDVLVTEDGPENLTR 243
crvDNA_42K TIGR00495
42K curved DNA binding protein; Proteins identified by this model have been identified in a ...
 3-119 1.30e-07

42K curved DNA binding protein; Proteins identified by this model have been identified in a number of species as a nuclear (but not nucleolar) protein with a cell cycle dependence. Various names given to members of this family have included cell cycle protein p38-2G4, DNA-binding protein GBP16, and proliferation-associated protein 1. This protein is closely related to methionine aminopeptidase, a cobolt-binding protein. [Unknown function, General]


Pssm-ID: 273105  Cd Length: 390  Bit Score: 51.81  E-value: 1.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022   3 TLKSDREIKGMQAAGDIMVGLFHALEDYIKPGITTWDVDHFAYNYITAHDATPGELNFEGYK---YSTCVSVNDMICHGC 79
Cdd:TIGR00495  13 SLSNPEVVTKYKMAGEIANNVLKSVVEACSPGAKVVDICEKGDAFIMEETAKIFKKEKEMEKgiaFPTCISVNNCVGHFS 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1655159022  80 PSK---DILVKDGDLLKVDTVINYHGYLSDSCHAFVAGTPSPE 119
Cdd:TIGR00495  93 PLKsdqDYILKEGDVVKIDLGCHIDGFIALVAHTFVVGVAQEE 135
PTZ00053 PTZ00053
methionine aminopeptidase 2; Provisional
 62-203 1.27e-06

methionine aminopeptidase 2; Provisional


Pssm-ID: 240246 [Multi-domain]  Cd Length: 470  Bit Score: 48.94  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  62 GYKYSTCVSVNDMICHGCPSK--DILVKDGDLLKVDTVINYHGYLSDSchAF-VAGtpSPEVQKLMDVTLKALYLGIDQA 138
Cdd:PTZ00053  208 GWAFPTGCSLNHCAAHYTPNTgdKTVLTYDDVCKLDFGTHVNGRIIDC--AFtVAF--NPKYDPLLQATKDATNTGIKEA 283

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1655159022 139 VVGNRIGDIGWAIQNYAEN-EMGYG-------VVREYIGHGIGP-TMHEKPDVPHYGeAGHGTRLKAGMTITIE 203
Cdd:PTZ00053  284 GIDVRLSDIGAAIQEVIESyEVEIKgktypikSIRNLNGHSIGPyIIHGGKSVPIVK-GGENTRMEEGELFAIE 356
PRK09795 PRK09795
aminopeptidase; Provisional
 77-204 9.86e-06

aminopeptidase; Provisional


Pssm-ID: 182080 [Multi-domain]  Cd Length: 361  Bit Score: 46.08  E-value: 9.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655159022  77 HGCPSkDILVKDGDLLKVDTVINYHGYLSDSCHAF-VAGTPSP-EVQKLMDV---TLKALYLGIDQAVVGNRIGDIGWAI 151
Cdd:PRK09795  195 HGKAS-DKIVAAGEFVTLDFGALYQGYCSDMTRTLlVNGEGVSaESHPLFNVyqiVLQAQLAAISAIRPGVRCQQVDDAA 273

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1655159022 152 QNYAEnEMGYGvvrEYI----GHGIGPTMHEKPDVphygEAGHGTRLKAGMTITIEP 204
Cdd:PRK09795  274 RRVIT-EAGYG---DYFghntGHAIGIEVHEDPRF----SPRDTTTLQPGMLLTVEP 322
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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