|
Name |
Accession |
Description |
Interval |
E-value |
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
5-419 |
1.42e-20 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 93.09 E-value: 1.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 5 KKKIAINTAYMYIRTFLAVIVSLFTSRIILEKLGVEDYGIYievGGIVGLLGFMNGVLANGTGRFITFELGRNEFDRLKR 84
Cdd:COG2244 1 LKKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLF---ALALSIVALLSVLADLGLSTALVRFIAEYREEELRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 85 TFSSMLTAHLLLALVVIVIMGFVGWWLIGHKLDIpanrlDAAYYVLCLSLFTTIFTLTQVPyTSLLIAHERMSVVAYWAL 164
Cdd:COG2244 78 LLSTALLLRLLLSLLLALLLLLLAPFIAALLGEP-----ELALLLLLLALALLLSALSAVL-LALLRGLERFKLLALINI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 165 FNTFAKLGILYLLAIMPFDklevyatllmlisltemvgnriycvrkfkesrvslgldkdILRPIFSYSSWSILTSCTLML 244
Cdd:COG2244 152 LSSLLSLLLALLLALLGLG----------------------------------------LWGLVLKYSLPLLLSGLLGLL 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 245 NGQGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPI 324
Cdd:COG2244 192 LTNLDRLLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGL 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 325 FFCCDDFLKVWLKTVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIYVLF-RYGSSPIA 403
Cdd:COG2244 272 ALLAPPLLSLLFGPEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIpRYGLVGAA 351
|
410
....*....|....*.
gi 1645985530 404 qsWVALITYFIMGTFL 419
Cdd:COG2244 352 --IATLLSYLVLLLLL 365
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
8-415 |
3.98e-18 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 86.44 E-value: 3.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 8 IAINTAYMYIRTFLAVIVSLFTSRIILEKLGVEDYGIYIEVGGIVGLLGfmngVLAN-GTGRFITFELGRNEFDRLKRTF 86
Cdd:cd13128 1 LAKNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFS----IFADlGLPTALVREIARYRKEKIREII 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 87 SSMLTAHLLLALVVIVIMGFVGWWLIGHKLDIpanrldaaYYVLCLSLFTTIFTLTQVPYTSLLIAHERMSVVAYWALFN 166
Cdd:cd13128 77 STSLVLKLILGILALLLLFLFAFLIAFYDPEL--------VLLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 167 TFAKLGILYLLAIMPFDkLEVYATLLMLISLTEMVGNRIYCVRKFKESRvSLGLDKDILRPIFSYSSWSILTSCTLMLNG 246
Cdd:cd13128 149 SVLSLILALILVLLGGG-LIGFALAYLIASVLSAILLLYIYRKKILLPK-FFSFDLKLAKELLRFSIPLALSGIFSLIYT 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 247 QGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYaAGDFIGSKHLLLESTQLSFYLMMIVTIPIFF 326
Cdd:cd13128 227 RIDTIMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELY-KNDKDELKKLLKKSFKYLFLISLPIAIGLFL 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 327 CCDDFLKVWLKTVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIYVL-FRYGSspIAQS 405
Cdd:cd13128 306 FAEPIITLLFGEEYLPAALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLLiPKYGI--IGAA 383
|
410
....*....|
gi 1645985530 406 WVALITYFIM 415
Cdd:cd13128 384 IATLISEFII 393
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
235-393 |
2.25e-05 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 44.86 E-value: 2.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 235 SILTSCTLMLNGQGVVMLLGMFfSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFigskHLLLESTQLSF 314
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHL-GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNF----KRAGVALRQGL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 315 YLMMIVTIPIFFCCDDFLKVWLK------TVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQF 388
Cdd:pfam01554 77 ILGLLLSLPIALLVLLFSEPILSlfgqdeEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNI 156
|
....*
gi 1645985530 389 PIIYV 393
Cdd:pfam01554 157 PLNYL 161
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
5-419 |
1.42e-20 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 93.09 E-value: 1.42e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 5 KKKIAINTAYMYIRTFLAVIVSLFTSRIILEKLGVEDYGIYievGGIVGLLGFMNGVLANGTGRFITFELGRNEFDRLKR 84
Cdd:COG2244 1 LKKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLF---ALALSIVALLSVLADLGLSTALVRFIAEYREEELRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 85 TFSSMLTAHLLLALVVIVIMGFVGWWLIGHKLDIpanrlDAAYYVLCLSLFTTIFTLTQVPyTSLLIAHERMSVVAYWAL 164
Cdd:COG2244 78 LLSTALLLRLLLSLLLALLLLLLAPFIAALLGEP-----ELALLLLLLALALLLSALSAVL-LALLRGLERFKLLALINI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 165 FNTFAKLGILYLLAIMPFDklevyatllmlisltemvgnriycvrkfkesrvslgldkdILRPIFSYSSWSILTSCTLML 244
Cdd:COG2244 152 LSSLLSLLLALLLALLGLG----------------------------------------LWGLVLKYSLPLLLSGLLGLL 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 245 NGQGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPI 324
Cdd:COG2244 192 LTNLDRLLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLLLGLPLALGL 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 325 FFCCDDFLKVWLKTVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIYVLF-RYGSSPIA 403
Cdd:COG2244 272 ALLAPPLLSLLFGPEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIpRYGLVGAA 351
|
410
....*....|....*.
gi 1645985530 404 qsWVALITYFIMGTFL 419
Cdd:COG2244 352 --IATLLSYLVLLLLL 365
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
8-415 |
3.98e-18 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 86.44 E-value: 3.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 8 IAINTAYMYIRTFLAVIVSLFTSRIILEKLGVEDYGIYIEVGGIVGLLGfmngVLAN-GTGRFITFELGRNEFDRLKRTF 86
Cdd:cd13128 1 LAKNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFS----IFADlGLPTALVREIARYRKEKIREII 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 87 SSMLTAHLLLALVVIVIMGFVGWWLIGHKLDIpanrldaaYYVLCLSLFTTIFTLTQVPYTSLLIAHERMSVVAYWALFN 166
Cdd:cd13128 77 STSLVLKLILGILALLLLFLFAFLIAFYDPEL--------VLLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 167 TFAKLGILYLLAIMPFDkLEVYATLLMLISLTEMVGNRIYCVRKFKESRvSLGLDKDILRPIFSYSSWSILTSCTLMLNG 246
Cdd:cd13128 149 SVLSLILALILVLLGGG-LIGFALAYLIASVLSAILLLYIYRKKILLPK-FFSFDLKLAKELLRFSIPLALSGIFSLIYT 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 247 QGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYaAGDFIGSKHLLLESTQLSFYLMMIVTIPIFF 326
Cdd:cd13128 227 RIDTIMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRISELY-KNDKDELKKLLKKSFKYLFLISLPIAIGLFL 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 327 CCDDFLKVWLKTVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIYVL-FRYGSspIAQS 405
Cdd:cd13128 306 FAEPIITLLFGEEYLPAALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLLiPKYGI--IGAA 383
|
410
....*....|
gi 1645985530 406 WVALITYFIM 415
Cdd:cd13128 384 IATLISEFII 393
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
48-419 |
3.68e-13 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 71.33 E-value: 3.68e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 48 VGGIVGLLGFMNGVLANGTGRFITFELGRNEFDRLKRTFSSMLTAHLLLALVVIVIMGFVGWWLIGHkLDIPANRLDAAY 127
Cdd:COG0534 49 AFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRL-LGADPEVLALAR 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 128 -YVLCLSLFTTIFTLTQVpYTSLLIAHERMSVVAYWALFNTFAKLGILYLLaIMPFDkLEV----YATLL-MLISLTEMV 201
Cdd:COG0534 128 dYLRIILLGLPFLLLFNV-LNGILRGLGDTKTPMIIMLIGNVLNIVLDPLL-IFGGG-LGVagaaLATVIsQAVSALLLL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 202 GNRIYCVRKFKESRVSLGLDKDILRPIFSYSSWSILTSCTLMLnGQGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNG 281
Cdd:COG0534 205 YYLFRKRSLLRLRLRDLRPDRKILKRILRIGLPAGLQQLAESL-GFLVLNALVARLGTAAVAAYGIALRIESLAFMPALG 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 282 FRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPIFFCCDDFLKVWLKT--VPDYTTIFLKIVLFQTLFNVF 359
Cdd:COG0534 284 LGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGLLLALLLFLFPEPIIGLFTDDpeVIALAATYLRIAALFQPFDGL 363
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1645985530 360 NTSFYQAINANGNLKRNAIMS-AGLSFLQFPIIYVLFRYGSSPIAQSWVALITYFIMGTFL 419
Cdd:COG0534 364 QFVLSGALRGAGDTRFPMIISlLRLWLVRLPLAYLLAFLGLGLTGVWLALPIGEVLRALLL 424
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
13-424 |
1.01e-11 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 66.96 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 13 AYMYIRTFLAVIVSLFTSRII--LEKLGVEDYGIYIEVGGIVGLLGFmngVLANGTGRFITFELGRNEFDRLKRTFSSML 90
Cdd:cd12082 2 APLLLSMLLQTLYNLVDTFFLgrLLGDALAAVGLAFPLIALLIALGV---GLSVGTSALISQAIGAGDEEKARRVLVQSI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 91 TAHLLLALVVIVIMGFVGWWLIGHKLDIPANRLDAAYYVLCLSLFTTIFTLTQVpYTSLLIAHERMSVVAYWALFNTFAK 170
Cdd:cd12082 79 VLAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAV-LSGILQGEGDTRTAMIISVLSNLLN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 171 LGILYLLAIMPFDKLE--VYATLLMLISLTEMVGNRIYCVRK----FKESRVSLGLDKDILRPIFSYSSWSILTSCTLML 244
Cdd:cd12082 158 ILLDPLLIFGLGPPELgiAGAALATVISYVIGALLLLIYLRKgkkiLKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 245 NGQGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPI 324
Cdd:cd12082 238 GLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 325 FFCCDDFLKVWLKT--VPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMS-AGLSFLQFPIIYVLFRYGSSP 401
Cdd:cd12082 318 LLFPEPILSLFTNDpeFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSlLSYWVVRLPLAYVLAYLGLGL 397
|
410 420
....*....|....*....|...
gi 1645985530 402 IAQSWVALITYFIMGTFLKPYLL 424
Cdd:cd12082 398 YGIWLALVISLILAALVLLLFFR 420
|
|
| MATE_tuaB_like |
cd13127 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
8-426 |
2.61e-07 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240532 [Multi-domain] Cd Length: 406 Bit Score: 52.87 E-value: 2.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 8 IAINTAYMYIRTFLAVIVSLFTSRIILEKLGVEDYGIyieVGGIVGLLGFMNGVLANGTGRFITfelgRNEfDRLKRTFS 87
Cdd:cd13127 1 AVSGAFWSAISQVVVQLLQFVVTIILARLLTPEDFGL---VAMATVFIAFAQLFSDLGLSSALI----QRK-DLTEEDLS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 88 SMLTAHLLLALVVIVIMGFVGWwLIGHKLDIPanRLDAAYYVLCLSLFTTIFTltqVPYTSLLIAHERMSVVAYWALFNT 167
Cdd:cd13127 73 TVFWLNLLLGLLLYLLLFLLAP-LIAAFYNEP--ELIPLLRVLSLSFLLSGLG---SVPRALLQRELRFKKLAIIELIST 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 168 FAKLGILYLLAIMPFdklEVYATLLMLI--SLTEMVGNRIYCVRkfkesRVSLGLDKDILRPIFSYSSWSILTSCTLMLN 245
Cdd:cd13127 147 LVSGVVAIVLALLGF---GVWALVAQQLvgALVSTVLLWILSRW-----RPRLSFSLASLKELLSFGSKLLGSNLLNYFS 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 246 GQGVVMLLGMFFSPAIVAARAISLQINQM-SDFFVNGFRTAVNPQIIKryAAGDFIGSKHLLLESTQLSFYLMMIVTIPI 324
Cdd:cd13127 219 RNLDNLIIGKFLGAAALGYYSRAYRLALLpVQNITGPITRVLFPALSR--LQDDPERLRRAYLKALRLLALITFPLMVGL 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 325 FFCCDDFLKV-----WLKTVPdyttiFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIYVLFRYGS 399
Cdd:cd13127 297 ALLAEPLVLLllgekWLPAVP-----ILQILALAGLFQPLSSLNGSLLLALGRTDLLLKLGLIKAVLTVLALLIGIPYGI 371
|
410 420
....*....|....*....|....*....
gi 1645985530 400 SPIAQSWV--ALITYFIMGTFLKPYLLVN 426
Cdd:cd13127 372 IGVAIAYViaSLLSFPLNLYLAGRLIGIS 400
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
19-415 |
6.93e-07 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 51.76 E-value: 6.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 19 TFLAVIVSLFTSRIILEKLGVEDYGIyIEVGGIVGLLGFMNGV-LANGTGRFITFELGRNEFDRLKRTFSSMLTAHLLLA 97
Cdd:cd13133 17 SMLSQTVMGFTDRAFLGRLSEVALAA-SGPAGVLYFAILMLFFgLSSGVQVFVAQYNGAGRYSRIGRVLWQGLYFSLLLA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 98 LVVIVIMGFVGWWLIGHKLDIPA-NRLDAAYY-VLCLSLFTTIF-----------TLTQVPYTSLLIAHERMSVVAYWAL 164
Cdd:cd13133 96 PLLALLSALAAPLLFLLLGHSPEvQALEVEYFrIRILGAPFSLLgaalraffsgiGRTRVVMVANLVMVVVNIVLDYALI 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 165 FNT--FAKLGIL-----YLLAimpfdklEVYATLLMLISLTEMVGNRIYCVRKFkesrvsLGLDKDILRPIFSYSSWSIL 237
Cdd:cd13133 176 FGKlgFPAMGIAgaaiaTVIA-------EAVSLLFFLLLLFRRKNRRRFGLRRA------WRFDRELLRRILRLGLPSGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 238 TSCTLMLNGQGVVMLLGMFfSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLM 317
Cdd:cd13133 243 QFFLDVGAFTVFFLLIGRL-GTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAYM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 318 MIVTIPIFFCCDDFLKVWLKT-----VPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQFPIIY 392
Cdd:cd13133 322 LLLGILFLLFPELLLSIFTPGadfalIAELAVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLYLLPPA 401
|
410 420
....*....|....*....|...
gi 1645985530 393 VLFRYGSSPIAQSWVALITYFIM 415
Cdd:cd13133 402 YLLVVLGAGLAGAWTVETVYVIV 424
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
51-419 |
8.45e-06 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 48.28 E-value: 8.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 51 IVGLLGFMNGVLANGTGRFITFELGRNEFDRLKRTFSSMLTAHLLLALVVIVIMGFVGWWLIGHKLDIPANRLDAAYYVL 130
Cdd:cd13137 45 VLWLLLVLNMALGTGTVALVSQSYGAGDYERARRALGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 131 CLSLFTTIFTLTQVPYTSLliaheR--------MSVVAYWALFNTFakLGILYLLAIMPFDKLEV----YATLL-----M 193
Cdd:cd13137 125 IVLLGIPFFFLSLVGNAAL-----RgagdtktpMYIMIIVNVLNIV--LDYVLIFGLWGFPGLGVagaaLATVIsrvvgA 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 194 LISLTEMVGNRIYCVRKFKESRVSLGLDKDILRpIFSYSSwsiltsctlmlnGQGVVMLLGMF--------FSPAIVAAR 265
Cdd:cd13137 198 LLLLFLLLRGRLPIKISFKGFRLDRKIIKKLLR-IGLPAG------------LEQLLRSLGFLvllaivasYGTAALAAY 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 266 AISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPIFFCCDDFLKVWLK--TVPDYT 343
Cdd:cd13137 265 QIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGLLGLLLFIFAPPLASLFTPdpEVIELG 344
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1645985530 344 TIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMS-AGLSFLQFPIIYVLFRYGSSPIAQSWVA-LITYFIMGTFL 419
Cdd:cd13137 345 VLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINlISMWLVRLPLAYLLGFVLGLGLTGIWLAmFVDTIVRAILL 422
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
235-393 |
2.25e-05 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 44.86 E-value: 2.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 235 SILTSCTLMLNGQGVVMLLGMFfSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFigskHLLLESTQLSF 314
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHL-GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNF----KRAGVALRQGL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 315 YLMMIVTIPIFFCCDDFLKVWLK------TVPDYTTIFLKIVLFQTLFNVFNTSFYQAINANGNLKRNAIMSAGLSFLQF 388
Cdd:pfam01554 77 ILGLLLSLPIALLVLLFSEPILSlfgqdeEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNI 156
|
....*
gi 1645985530 389 PIIYV 393
Cdd:pfam01554 157 PLNYL 161
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
51-382 |
3.01e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 43.26 E-value: 3.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 51 IVGLLGFMNGVLANGTGRFITFELGRNEFDRLKRTFSSMLTAHLLLALVVIVIMGFVGWWLIgHKLDIPANRLDAAYYVL 130
Cdd:cd13134 47 ILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIAGVALLFNLLLGLVFSLLLLFFGAELL-RLMGLPPELLALGSTYL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 131 CLSLFTTIFTLTQVPYTSLLIAHERMSVVAYWALF----NTFakLGILYLLAIMPFDKLEV----YATllmLIS-LTEMV 201
Cdd:cd13134 126 RIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLImnilNIV--GNYLLIFGWFGLPKLGVagvaIST---VISrAVGLV 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 202 GNRIYCVRKFKE---SRVSLGLDKDILRPIFSYSSWSILTSCTLMLngqGVVMLLGMF--FSPAIVAARAISLQINQMSD 276
Cdd:cd13134 201 LLFILLFRKLKIrfrLKDLRPFPKKLLKKILKIGLPSAGEELSYNL---SQTVITAFIarLGTAALAARTYASNISMFVF 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 277 FFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPIFFCCDDFLKvWLKTVPD---YTTIFLKIVLFQ 353
Cdd:cd13134 278 LFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSLAVALLLALFREPILG-LFTDDPEiiaLGKTLLLISILL 356
|
330 340
....*....|....*....|....*....
gi 1645985530 354 TLFNVFNTSFYQAINANGNLKRNAIMSAG 382
Cdd:cd13134 357 EPGRAFNIVLIGSLRAAGDARFPVLIGII 385
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
174-394 |
2.89e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 40.25 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 174 LYLLAIMPFDKLEV----YATLL-----MLISLTEMVGNRiycvRKFKESRVSLGLDKDILRPIFSYSSWSILTSCTLML 244
Cdd:cd13142 180 LLIFGIGPFPGLGVagaaLATVIsrgiaAVIGLYLLFKGR----VGLKISLRDLKPDWEWLKKIFRIGLPSSIEQSARAL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 245 nGQGVVMLLGMFFSPAIVAARAISLQINQMSDFFVNGFRTAVNPQIIKRYAAGDFIGSKHLLLESTQLSFYLMMIVTIPI 324
Cdd:cd13142 256 -GFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALLIFLILVIGGVLA 334
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1645985530 325 FFCCDDFLKVWLK--TVPDYTTIFLKIVL----FQTLFNVFNTSFYQAinanGNLKRNAIMS-AGLSFLQFPIIYVL 394
Cdd:cd13142 335 FLFAEPIVRVFINdpEVIKEGADFLRIVApsfpFFGLFQVINGAFRGS----GHTLTAMIISiLRLWVIRIPLAYLL 407
|
|
| MATE_epsE_like |
cd13129 |
Multidrug and toxic compound extrusion family and similar proteins; This model represents a ... |
26-238 |
8.71e-03 |
|
Multidrug and toxic compound extrusion family and similar proteins; This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins, including Ralstonia solanaceraum GMI1000 epsE, which may be involved in exporting exopolysaccharide EPS I, a virulence factor. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240534 [Multi-domain] Cd Length: 411 Bit Score: 38.62 E-value: 8.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 26 SLFTSRIILEKLGVEDYGIYIEVGGIVGLLGFMNGV-LANGTGRFITfELGRNEFDRLKRTFSSMLTAHLLLALVVIVIM 104
Cdd:cd13129 20 VFLTNIMVARSLGKHVFGEFGVIQVTIGLLGTFAGFgLGLAATKVIA-ETKDVDPERAGRIIGLSILLAVVTGALAATVL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1645985530 105 GFVGWWLIGHKLDIPanRLDAAYYVLCLSLFTTIFTLTQVPYTSLLIAHERMSVVAYWALFNTFAKLGILyllaiMPFDK 184
Cdd:cd13129 99 FLSATWIAIATLNAP--HLAELLRIAAIILILTAFTGAQTGFLSGFEAFRAIARVNIWAGLLLLPLMWIG-----VYIRG 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1645985530 185 LEVYATLLMLISLTEMVGNRIYCVRKFKESR--VSLGLDKDILRPIFSYSSWSILT 238
Cdd:cd13129 172 LVGAVVILLASAAGNVASNSLILRRECQNQRgpVRTGLTWQELRVLFKFSLPSVLS 227
|
|
| |
