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Conserved domains on  [gi|1625655466|gb|QCF62014|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Poecilimon ciplaki denizliensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-330 3.18e-79

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 244.73  E-value: 3.18e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   1 PSKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHlsdMT 80
Cdd:MTH00160    5 SSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM---LN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 LLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNtFIVLVITSSIIIGSLG 160
Cdd:MTH00160   82 LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 161 GLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIK-LNPNLKFCLFFLL 239
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNnKSKKIKFLLFLNL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 240 LSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETKWIENIPYNLtTYFTLMVST 319
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNK-FSLILNFLS 319

                         330
                  ....*....|.
gi 1625655466 320 TISSLGLLLCT 330
Cdd:MTH00160  320 FISLFGLILSS 330
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-330 3.18e-79

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 244.73  E-value: 3.18e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   1 PSKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHlsdMT 80
Cdd:MTH00160    5 SSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM---LN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 LLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNtFIVLVITSSIIIGSLG 160
Cdd:MTH00160   82 LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 161 GLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIK-LNPNLKFCLFFLL 239
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNnKSKKIKFLLFLNL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 240 LSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETKWIENIPYNLtTYFTLMVST 319
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNK-FSLILNFLS 319

                         330
                  ....*....|.
gi 1625655466 320 TISSLGLLLCT 330
Cdd:MTH00160  320 FISLFGLILSS 330
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 20-277 1.04e-30

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 117.41  E-value: 1.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  20 SSSWFGTWMGLEINLLSFIPLMT-NTKNTLSTEASLKYFLIQALASSILLFSIIFMHLS----DMTLLLNQDLFLILISS 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYtgtlSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  95 PLLL----------KMGAAPFHFWFPGTMEGLSWVNCLIL-MTWQKIAPFMLI-------SYVIVMNTFIVLVITSSIII 156
Cdd:pfam00361  81 LLLLfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 157 GSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGEN----LWLFYFSIYTFLSTSIIFLFQSFQL-----FHLNQNF-LIK 226
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqAAIFHLLTHGLFSAGLFLCAGSVIYrrvhtRNIRDYGgLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1625655466 227 LNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITT 277
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-319 2.77e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 105.58  E-value: 2.77e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITlisGTLISISSSSWFGTWMGLEINLLSFIPL-MTNTKNTLSTEASLKYFLIQALASSILLF--SIIF-----MH 75
Cdd:COG1007   108 LLFATL---GMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYgiSLLYgatgsLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  76 LSDMTLLLNQDLFLILISSPLLL--------KMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF---------MLISY 138
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 139 VIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLW----LFYFSIYTFLSTSIIFLFQSF 214
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGvsaaLFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 215 --------QLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLR 286
Cdd:COG1007   345 srkggeaeEIEDLAG--LARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1625655466 287 LTFAGFLFSYQETkwiENIPYNLTTYFTLMVST 319
Cdd:COG1007   423 VVKAMYFDEPEEE---APISAPPGLRVALVIAA 452
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-319 2.98e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 96.94  E-value: 2.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  11 ISGTLISISSSSWFGTWMGLEINLLSFIPLMT-NTKNTLSTEASLKYFLIQALASSILLFSIIFM-------HLSDMTLL 82
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  83 LNQDLFLILISSP--------LLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF-------MLISYVIVMNTFIV 147
Cdd:TIGR01770 192 LSNGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFavflrlfLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 148 LVITS--SIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENL----WLFYFSIYTFLSTSIIFLFQSFQLFHLNQ 221
Cdd:TIGR01770 272 LAIIAflSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 222 NF-------LIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAgfLF 294
Cdd:TIGR01770 352 IEyisdfagLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKV--MY 429

                         330       340
                  ....*....|....*....|....*
gi 1625655466 295 SYQETKWIENIPYNLTTYFTLMVST 319
Cdd:TIGR01770 430 FDKPERRIPSNPQSKAQSLLLSISA 454
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-330 3.18e-79

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 244.73  E-value: 3.18e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   1 PSKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHlsdMT 80
Cdd:MTH00160    5 SSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM---LN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 LLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNtFIVLVITSSIIIGSLG 160
Cdd:MTH00160   82 LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 161 GLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIK-LNPNLKFCLFFLL 239
Cdd:MTH00160  161 GLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNnKSKKIKFLLFLNL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 240 LSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETKWIENIPYNLtTYFTLMVST 319
Cdd:MTH00160  241 LSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNK-FSLILNFLS 319

                         330
                  ....*....|.
gi 1625655466 320 TISSLGLLLCT 330
Cdd:MTH00160  320 FISLFGLILSS 330
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 4-290 3.02e-61

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 198.92  E-value: 3.02e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSII--FMHLSDMTL 81
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIinLMYSGQWTI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  82 L-LNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFML---ISYVIVMNTFIVLVITsSIIIG 157
Cdd:MTH00105   87 TkLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIlyqISPSINPNLLLTLAIL-SILIG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 158 SLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIiflfqsFQLFHLNQNFLIKL-------NPN 230
Cdd:MTH00105  166 GWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTM------FMLLMLNSSTTTLSlshtwnkTPL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 231 LKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFA 290
Cdd:MTH00105  240 MTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYS 299
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 2-289 1.33e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 189.65  E-value: 1.33e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   2 SKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLS---- 77
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNtgqw 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  78 DMTLLLNQdLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF-MLISYVIVMNTFIVLVI-TSSII 155
Cdd:MTH00112   85 DITQLTNP-TSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLtLLLMTSNSLNPTLLLTLaILSTL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 156 IGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIiflfqsFQLFHLNQNFLIK-------LN 228
Cdd:MTH00112  164 IGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPM------FLTLNTTSTKTLKdmmtswtKS 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1625655466 229 PNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTF 289
Cdd:MTH00112  238 PTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTY 298
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 2-290 2.23e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 188.98  E-value: 2.23e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   2 SKLLFSITLisGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSII----FMHLS 77
Cdd:MTH00070    7 SILLSSLAL--GTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTinawFTGEW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  78 DMTLLLNQdLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFML---ISYVIVMNTFIVLVITsSI 154
Cdd:MTH00070   85 TIMNMQTP-LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALliqISHLLNSNLLIIMGLL-ST 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 155 IIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFL--IKlNPNLK 232
Cdd:MTH00070  163 LIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSswSK-NPTLT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1625655466 233 FCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFA 290
Cdd:MTH00070  242 SMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYA 299
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-300 9.80e-57

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 186.63  E-value: 9.80e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   1 PSKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLSDMT 80
Cdd:MTH00144    4 PSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 lllnqDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLIS---YVIVMNTFIVLVITSSIIIG 157
Cdd:MTH00144   84 -----WFSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSnflDLYWLAYLLCVISVLSALVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 158 SLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIKLNPNLKFCLFF 237
Cdd:MTH00144  159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIIS 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1625655466 238 LLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETK 300
Cdd:MTH00144  239 LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKK 301
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 4-328 8.92e-55

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 182.44  E-value: 8.92e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLSDMTLLL 83
Cdd:MTH00041    7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  84 NQ---DLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNTFIVLVI--TSSIIIGS 158
Cdd:MTH00041   87 NGplnTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILcgILSVLVGG 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 159 LGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHL-NQNFLIKLNPNLKFCLFF 237
Cdd:MTH00041  167 WGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLsHLNKLSQLNPISAFLFIL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 238 LLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETKWIENIPYNLTTYFTLMV 317
Cdd:MTH00041  247 SILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326

                         330
                  ....*....|.
gi 1625655466 318 STTISSLGLLL 328
Cdd:MTH00041  327 ILSILSSISIL 337
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-295 1.01e-51

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 173.81  E-value: 1.01e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   1 PSKLLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSiifMHLSDMT 80
Cdd:MTH00011    6 PTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG---MTMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 LLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMN--TFIVLVITSSIIIGS 158
Cdd:MTH00011   83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNilPMMTSMAAMSALAGG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 159 LGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLI-KLNPNLKFCLFF 237
Cdd:MTH00011  163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKIsSMSQTTSMSLFI 242

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1625655466 238 LLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFS 295
Cdd:MTH00011  243 MLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 4-290 1.53e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 171.14  E-value: 1.53e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITLisGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSII---FMHLSDMT 80
Cdd:MTH00135    9 LLFSLGL--GTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnaWLTGQWDI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  81 LLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMN-TFIVLVITSSIIIGSL 159
Cdd:MTH00135   87 QQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNpTLLITLGLTSTLVGGW 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 160 GGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYtFLSTSIIFLfqsfqLFHLNQNFLIKL-------NPNLK 232
Cdd:MTH00135  167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTY-IIMTSSAFL-----TFKLNSSTKINTlatswtkAPALT 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1625655466 233 FCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFA 290
Cdd:MTH00135  241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYA 298
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 4-330 5.51e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 169.76  E-value: 5.51e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLSDMTLLL 83
Cdd:MTH00200    7 PLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  84 NQDLFLILISSPL---LLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLIS--YVIVMNTFIVLVITSSIIIGS 158
Cdd:MTH00200   87 SEMLGPLSETLILlalALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLVGG 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 159 LGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIKL-NPNLKFCLFF 237
Cdd:MTH00200  167 WGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTkNPILSMLLGL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 238 LLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSYQETKWIENIPYNLTTYFTLMV 317
Cdd:MTH00200  247 TLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLLVG 326

                         330
                  ....*....|...
gi 1625655466 318 STTISSLGLLLCT 330
Cdd:MTH00200  327 LLLLLSILGLPLT 339
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 5-328 8.86e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 160.61  E-value: 8.86e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   5 LFSITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLSDMTLLLN 84
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  85 QDLFLILISSplllKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNTFIVLVITSSIIIGSLGGLNQ 164
Cdd:MTH00197   82 VVLVILGLLL----KLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 165 TSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIKLNPNLKFCLFFLLLSLGG 244
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 245 -LPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFLFSyqetKWIENIPYNLTTYFTLMVSTTISS 323
Cdd:MTH00197  238 gLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS----NWMINFLMKINLLYSGLFILLMMM 313


                  ....*
gi 1625655466 324 LGLLL 328
Cdd:MTH00197  314 LPLLM 318
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 20-277 1.04e-30

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 117.41  E-value: 1.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  20 SSSWFGTWMGLEINLLSFIPLMT-NTKNTLSTEASLKYFLIQALASSILLFSIIFMHLS----DMTLLLNQDLFLILISS 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYtgtlSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  95 PLLL----------KMGAAPFHFWFPGTMEGLSWVNCLIL-MTWQKIAPFMLI-------SYVIVMNTFIVLVITSSIII 156
Cdd:pfam00361  81 LLLLfllilvgflfKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 157 GSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGEN----LWLFYFSIYTFLSTSIIFLFQSFQL-----FHLNQNF-LIK 226
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqAAIFHLLTHGLFSAGLFLCAGSVIYrrvhtRNIRDYGgLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1625655466 227 LNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITT 277
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-319 2.77e-25

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 105.58  E-value: 2.77e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITlisGTLISISSSSWFGTWMGLEINLLSFIPL-MTNTKNTLSTEASLKYFLIQALASSILLF--SIIF-----MH 75
Cdd:COG1007   108 LLFATL---GMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYgiSLLYgatgsLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  76 LSDMTLLLNQDLFLILISSPLLL--------KMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF---------MLISY 138
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 139 VIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLW----LFYFSIYTFLSTSIIFLFQSF 214
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGvsaaLFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 215 --------QLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLR 286
Cdd:COG1007   345 srkggeaeEIEDLAG--LARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1625655466 287 LTFAGFLFSYQETkwiENIPYNLTTYFTLMVST 319
Cdd:COG1007   423 VVKAMYFDEPEEE---APISAPPGLRVALVIAA 452
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-287 3.03e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 102.40  E-value: 3.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   8 ITLISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTL-STEASLKYFLIQALASSILLFSIIFMH-------LSDM 79
Cdd:MTH00199  104 LIVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAySTEAGLKYFVLGAVSSGLFLFGCALLYgltgetsIQGI 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  80 TLLLNQDLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNTFIVLVITSSIIIGSL 159
Cdd:MTH00199  184 NSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 160 GGLNQTSLRKLMAYSSINHLGWMMAALTTGEN----LWLFYFSIYTFLSTSIIFLFQSFQLfhlNQNFLIKL------NP 229
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGFILFGVAIGSFesiqASLIYMIIYVIMSICSFSIILSLKL---TKGLIVEVsglsrkNP 340

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1625655466 230 NLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRL 287
Cdd:MTH00199  341 VIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-287 1.15e-23

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.05  E-value: 1.15e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   4 LLFSITlisGTLISISSSSWFGTWMGLEI-NLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLSDMTLL 82
Cdd:PRK05777  109 VLFALL---GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  83 LNQDLFLILISSPLLL---------------KMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLI---------SY 138
Cdd:PRK05777  186 FAGIAKALADGSGNSLlllfglvfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGL 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 139 VIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENL----WLFYFSIYTFLST---SIIFL- 210
Cdd:PRK05777  266 SEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLgafGVISLl 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 211 ----FQSFQLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLR 286
Cdd:PRK05777  346 rrkgGEAESISDFAG--LSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423


                  .
gi 1625655466 287 L 287
Cdd:PRK05777  424 V 424
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-287 1.58e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 99.33  E-value: 1.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  13 GTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTL-STEASLKYFLIQALASSILLFSIIFM-------HLSDMTLLLN 84
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGySAEAGLKYFVLGALSSGLFLFGCALLcgttgglHLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  85 QDLFLILISSPL---------LLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF-MLISYVIVMNTFIVLVITSsI 154
Cdd:MTH00196   85 SGQSFSSVSVPIgylliivalLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFsILVSIGLNVNILLIGGLFS-L 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 155 IIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGE----NLWLFYFSIYTFLStsiIFLFQSFQLFHLNQNFLI----- 225
Cdd:MTH00196  164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMS---ICVFSIILALNVYKNLIIefsgl 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1625655466 226 -KLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRL 287
Cdd:MTH00196  241 sRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 11-319 2.98e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 96.94  E-value: 2.98e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  11 ISGTLISISSSSWFGTWMGLEINLLSFIPLMT-NTKNTLSTEASLKYFLIQALASSILLFSIIFM-------HLSDMTLL 82
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  83 LNQDLFLILISSP--------LLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPF-------MLISYVIVMNTFIV 147
Cdd:TIGR01770 192 LSNGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFavflrlfLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 148 LVITS--SIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENL----WLFYFSIYTFLSTSIIFLFQSFQLFHLNQ 221
Cdd:TIGR01770 272 LAIIAflSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 222 NF-------LIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAgfLF 294
Cdd:TIGR01770 352 IEyisdfagLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKV--MY 429

                         330       340
                  ....*....|....*....|....*
gi 1625655466 295 SYQETKWIENIPYNLTTYFTLMVST 319
Cdd:TIGR01770 430 FDKPERRIPSNPQSKAQSLLLSISA 454
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-287 1.39e-15

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 77.11  E-value: 1.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  10 LISGTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFM----------HLSDM 79
Cdd:COG0651   116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLygatgtlnmaDLAAR 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  80 TLLLNQDLFLILISSPLL---LKMGAAPFHFWFPGTM-EGLSWVNCLI--LMTwqKIAPFMLISYVIVM---------NT 144
Cdd:COG0651   196 LAELDPGLLLAAFALLLVgfgIKAALFPLHFWLPDAYpAAPSPVSALLsgLLT--KVGVYAILRVLTLLfgadpalflGT 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 145 FIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYT----------FLST-SIIFLFQS 213
Cdd:COG0651   274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhalakallFLAAgAIERATGT 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1625655466 214 FQLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRL 287
Cdd:COG0651   354 RDLDKLGG--LGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 13-287 2.39e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 70.66  E-value: 2.39e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  13 GTLISISSSSWFGTWMGLEINLLSFIPLMTNTKNTLST---------EASLKYFLIQALASSILLF-------------- 69
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFgcalyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  70 --SIIFMHLSDMTLLLNQ-DLFLILISSPLLLKMGAAPFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLISYVIVMNTFI 146
Cdd:MTH00198  280 lgTILSATLETTNIELRQgSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLL 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 147 VLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTG-----ENLWLF--YFSIYTFLSTSIIFLFQSFQLFHL 219
Cdd:MTH00198  360 LSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGtyeslQASWTYavTYLVSALASFTVICTLEEFGTRTP 439

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 220 NQ-------------------NFLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIII-------M 273
Cdd:MTH00198  440 TSrqrdgsfgnynlvrrlvdlTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIyylvalfA 519

                         330
                  ....*....|....
gi 1625655466 274 VITTLLTLFYYLRL 287
Cdd:MTH00198  520 IICTCISAFYYIRI 533
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 30-292 2.58e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 67.21  E-value: 2.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  30 LEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFMHLS----DMTLLLNQDLF-------LILISSPLLL 98
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVtgtlNMADLAGALAEnptvvtaFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  99 KMGAAPFHFWFPGTM-EGLSWVNCLILMTWQKIAPFMLI-----------SYVIVMNTFIVLVITSSIIIGSLGGLNQTS 166
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYALIriyftvfggdfRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 167 LRKLMAYSSINHLGWMMA--ALTTGENLW--LFY------FSIYTFLSTSIIFL-FQSFQLFHLNQnfLIKLNPNLKFCL 235
Cdd:PRK08375  295 VKRVLAYSTVSQMGYILLglALLTPLALAagLLHllhhalMKGALFLAAGAIEVtYGTRRLSELSG--LGRRMPLTAAAF 372

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1625655466 236 FFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGF 292
Cdd:PRK08375  373 AVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAF 429
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 135-328 7.44e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 56.90  E-value: 7.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 135 LISYVIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWLFYFSIYT----------FLS 204
Cdd:PRK12667  287 LIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksllFLA 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 205 T-SIIFLFQSFQLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFY 283
Cdd:PRK12667  367 SgVFIHAAGTRDIDELAG--LGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVG 444

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1625655466 284 YLRLTFAGFLFSYQETKWIENIPYNLTTYFTLMVSTTISSLGLLL 328
Cdd:PRK12667  445 YFRAWYSLFFGKPKSGEEVEHKESPSMSVVILVLALAVLILGILA 489
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
49-286 4.08e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.21  E-value: 4.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  49 STEASLKYFLIQALASSILLFSIIFM--------HLSDMT--LLLNQDLFLILISSPLL----LKMGAAPFHFWFPGTME 114
Cdd:PRK02504  159 SNEAALKYLLIGAASSAIFLYGSSLLyglsggstQLSAIAlaLITSPSLGLALALVFVIagiaFKISAVPFHQWTPDVYE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 115 GLSWVNCLILMTWQKIAPFMLISYVIVMN----------TFIVLVITSsIIIGSLGGLNQTSLRKLMAYSSINHLGWMMA 184
Cdd:PRK02504  239 GSPTPVVAFLSVGSKAAGFALAIRLLVTAfpsfdeqwklLFTALAILS-MVLGNVVALAQTSMKRMLAYSSIGQAGFVMI 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 185 ALTTGEN----LWLFYFSIYTFLSTSIiflFQSFQLFHLNQNF--------LIKLNPNLKFCLFFLLLSLGGLPPFLGFL 252
Cdd:PRK02504  318 GLVAGTEagyaSMVFYLLAYLFMNLGA---FACVILFSLRTGTdqisdyagLYQKDPLLTLGLSLCLLSLGGIPPLAGFF 394

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1625655466 253 PKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLR 286
Cdd:PRK02504  395 GKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
144-292 8.63e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 50.33  E-value: 8.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 144 TFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWL----FYF-------SIYTFLSTSIIFLFQ 212
Cdd:PRK12663  273 PLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALGTPAGIngaiFYLvhdmvvkTALFLIAGSLVRLTG 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 213 SFQLFHLNQnfLIKLNPNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGF 292
Cdd:PRK12663  353 YRSLQYLGG--LYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFLAY 430
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 51-293 1.20e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 49.71  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  51 EASLKYFLIQALASSILLFSI--------------IFMHLSDMTLLLNQdLFLILISSPLLLKMGAAPFHFWFP-GTMEG 115
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIallygqygtlnmayLAVKMSENPTVVAK-IALALFIAGLAMKSGAVPVHMWLPdAYPAA 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 116 LSWVNCLILMTWQ----KIAPFMLISYVIVMNT-----FIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAAL 186
Cdd:PRK08376  251 PSSISAMLLVIKQaglyALARVLFSIYGPAINLatvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGL 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 187 TTGenlwlfYFSIYTFLSTSIIFLFQSFQLFHLNQNFLIK------------------LN---------PNLKFCLFFLL 239
Cdd:PRK08376  331 GVG------LAALGDPAMASYGEIALAGGIYHIVNHALYKallfltagaviyetgtrnLNelgglartmPKTTIAFLIGA 404

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1625655466 240 LSLGGLPPFLGFLPKWLIIQALVDTNYLsLIIIMVITTLLTLFYYLRLTFAGFL 293
Cdd:PRK08376  405 AAIVGLPPFNGFASKWLIYESSALFNPI-LGVIAMIGSVLTLASFVKVFHTAFF 457
PRK12650 PRK12650
DUF4040 family protein;
104-292 2.32e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 49.27  E-value: 2.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 104 PFHFWFPGTMEGLSWVNC-LILMTWQKIAPFMLISYVIVMN---TFIVLVITSSI---IIGSLGGLNQTSLRKLMAYSSI 176
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAfLHAAAVVKAGIYLLLRFSPVFHdvaVWNWLLIIVGMitaLMGAVFAVQKTDLKKLTAYSTV 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 177 NHLGWMMAALTTGENLWLFYFSIYTFLSTsiifLFQSfQLFHL--------------NQNFLIKLNPNLKFCLFFLLLSL 242
Cdd:PRK12650  306 SQLGWIVATIGVGTPFALTAAVVHTLAHA----LFKS-SLFMLigvvdhqagtrdirRLGSLWRRMPFTFVSVTIAALSM 380

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1625655466 243 GGLPPFLGFLPKWLIIQALVDTNYLS-----LIIIMVITTLLTLFYYLRLTFAGF 292
Cdd:PRK12650  381 AAVPPLFGFVSKEGMLTAFLEAPGGNagvvlLLVGAALGAVFTFAYSARLVLGAF 435
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 104-293 2.65e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 49.00  E-value: 2.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 104 PFHFWFPGTMEGLSWVNCLI-----------LMTwqKIAPfmLISYVIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMA 172
Cdd:COG1009   229 PLHFWLPDAMEGPTPVSALLhaatmvkagvyLLA--RLSP--LFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVLA 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 173 YSSINHLGWMMAALTTGeNLWLFYFSIYT--------FLST-SIIFLFQSFQLFHLNQnfLIKLNPNLKFCLFFLLLSLG 243
Cdd:COG1009   305 YSTVSQLGYMFLALGVG-AYVAALFHLLThaffkallFLGAgSVIHATGTRDIRKMGG--LRKKMPITAITFLIGALSLA 381

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1625655466 244 GLPPFLGFLPKWLIIQALVDTNYLSLI--IIMVITTLLTLFYYLRLTFAGFL 293
Cdd:COG1009   382 GIPPFAGFFSKEAILEAALEAGGLGPLllAVALLGAFLTAFYSFRLFFLVFF 433
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
133-321 3.33e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 45.41  E-value: 3.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 133 FMLISYVIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWL---FYFSIYTFLSTSIIF 209
Cdd:PRK06277  256 FGGLSYFPSAQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIvagIFHAINHVIYKSALF 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 210 LFQSFQLFHLNQNFLIKLN------PNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFY 283
Cdd:PRK06277  336 LGAGIVSYRTKTSNLRKLGgllpvmPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVS 415

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1625655466 284 YLRLTFAGFLFSYQETKWIENIPYNLTTYFTLMVSTTI 321
Cdd:PRK06277  416 MMKAFYLIYLKPKPEELEYKNKKVPKYAVFSLAVLTIL 453
ndhB CHL00049
NADH dehydrogenase subunit 2
 49-287 7.79e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.22  E-value: 7.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  49 STEASLKYFLIQALASSILLFSIIFMH-LSDMTL--------LLNQDLFLILISSPLLL--------KMGAAPFHFWFPG 111
Cdd:CHL00049  160 SNEATMKYLLMGGASSSILVYGFSWLYgLSGGEIelqeivngLINTQMYNSPGISIALIfitvgigfKLSLAPFHQWTPD 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 112 TMEGLSWVNCLILMTWQKIAPFMLISYVIVM---------NTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWM 182
Cdd:CHL00049  240 VYEGSPTPVVAFLSVTSKVAASALATRIFDIpfyfssnewHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYV 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 183 MAALTTGENLW-----LFYFSIYTFLSTSIIFLFQSFQLFHLNQNF-----LIKLNPNLKFCLFFLLLSLGGLPPFLGFL 252
Cdd:CHL00049  320 IIGIIVGDSNDgyasmITYMLFYIFMNLGTFACIVLFGLRTGTDNIrdyagLYTKDPFLALSLALCLLSLGGIPPLAGFF 399

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1625655466 253 PKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRL 287
Cdd:CHL00049  400 GKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 49-293 1.61e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.45  E-value: 1.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  49 STEASLKYFLIQALASSILLFSI--------------IFMHLSDMTLLLNQDLFLILISSPLLLKMGAAPFHFWFPGTME 114
Cdd:PRK08668  145 SRKASLKYFVLSAIGAYAMLYAIfliyaktgtfdfadISQGLINDTSTGFALIVFLFLLAFGVAKAGIFPLHVWAPDAYS 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 115 ------------GLS-------WVNCLILMTWQKIAPFMLISYVIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSS 175
Cdd:PRK08668  225 eapqsfsavlsgQLSklgaygfLLVLYVLPGTKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSS 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 176 INHLGWMMAALTTGENL----WLFY------FSIYTFLSTSIIFLFQSFQLFHlNQNFLIKLNPNLKFCLFFLLLSLGGL 245
Cdd:PRK08668  305 VANGGYILVGLGLGTSLgfagGLFHvfnhalFKGLFFLIFAAVIYRTGTTKIS-EMGGLIEKMPFTFAMYLVAIISLAGI 383

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1625655466 246 PPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRLTFAGFL 293
Cdd:PRK08668  384 PPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLAGVFL 431
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 105-300 2.04e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 43.14  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 105 FHFWFPGTMEGLSWVNCLI-LMTWQKIAPFMLI--SYVIVMNTFIVLVITssiIIGSLG-------GLNQTSLRKLMAYS 174
Cdd:MTH00020  229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrsSPLFEQAPLALIIVT---IVGSLTvffaatvGLVQNDLKKVIAYS 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 175 SINHLGWM-MAALTTGENLWLF------YFSIYTFLST-SIIFLFQSFQLFHlNQNFLIKLNPNLKFCLFFLLLSLGGLP 246
Cdd:MTH00020  306 TCSQLGYMvVACGLSHYSISLFhlmnhaFFKALLFLSAgSVIHALSDEQDMR-KMGGLISFLPLTYIFFLIGSLSLMGFP 384

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1625655466 247 PFLGFLPKWLIIQALVDTNYLSLII-IMVITTLLTLFYYLRLTFAGFLFSYQETK 300
Cdd:MTH00020  385 YLTGFYSKDLILELAFGQYYLIFAYwLGCFSALLTAFYSIRLIYLTFLSNTNLKK 439
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
104-292 3.56e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 42.32  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 104 PFHFWFPGTMEGLSWVNCLILMTWQKIAPFMLI-------SYVIVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSI 176
Cdd:PRK07376  245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVarmypvfEQFPAVMTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 177 NHLGWMMAALTTGE-NLWLF------YFSIYTFL-STSIIFLFQSFqLFH---LNQNF-----LIKLNPNLKFCLFFLLL 240
Cdd:PRK07376  325 SQLGYMVMAMGCGAySAGLFhlmthaYFKAMLFLgSGSVIHGMEEV-VGHdpvLAQDMrlmggLRKYMPITAITFLIGCL 403

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1625655466 241 SLGGLPPFLGFLPKWLIIQALVDTNYLsLIIIMVITTLLTLFYYLRLTFAGF 292
Cdd:PRK07376  404 AISGIPPFAGFWSKDEILGAAFEANPA-LWFVGFLTAGMTAFYMFRMYFLTF 454
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 52-186 1.86e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 39.68  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  52 ASLKYFLIQALASSILLFSIIFMHLS------DMTLLLNQDLFLILISSPLLL-------KMGAAPFHFWFPGTME---- 114
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLagaltfDIAELAAAPLPLTAQLLLFLAffiafavKVPMFPFHTWLPDAHVeapt 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 115 ----------------GLSWVNCLIL-MTWQKIAPFMLISYVIvmntfivlvitsSIIIGSLGGLNQTSLRKLMAYSSIN 177
Cdd:COG1008   242 agsvllagvllkmggyGLLRFALPLFpEASAYFAPLLAALGVI------------GIIYGALVALAQTDLKRLIAYSSVS 309


                  ....*....
gi 1625655466 178 HLGWMMAAL 186
Cdd:COG1008   310 HMGFVLLGI 318
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 52-189 3.36e-03

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 39.15  E-value: 3.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  52 ASLKYFLIQALASSILLFSIIFM-----HLSDMTLLLNQDLFLILISSPLL-------LKMGAAPFHFWFPGTMEGLSWV 119
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLyflggGTFDLLELLNLPLPFGVQTWLFLaffiafaVKVPLFPLHTWLPDAHVEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1625655466 120 NCLILM-TWQKIAPFMLISYVIVM--------NTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTG 189
Cdd:TIGR01972 237 GSVILAgVLLKMGTYGFLRFNLPLfpdaslyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSF 315
PRK12646 PRK12646
DUF4040 family protein;
104-300 3.67e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 38.97  E-value: 3.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 104 PFHFWFPGTMEGLSWVNC-LILMTWQKIAPFMLISYVIVM---NTFIVLVITSSII---IGSLGGLNQTSLRKLMAYSSI 176
Cdd:PRK12646  228 PFHIWLPRAMAAPTPVSAyLHSATMVKAGIFLLFRFTPLLglsNMYIYIVTFVGLItmlFGSITALKQWDLKGILAYSTI 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 177 NHLGWMMAALTTGENlwLFYFSIYTFLSTSIIFLFQSfqLFHLNQNFLIK---------------------------LNP 229
Cdd:PRK12646  308 SQLGMIMAMVGIGGG--YAQHQQDAIASIYVFVLFAA--LFHLMNHAIFKcalfmgvgiidheagtrdirilsgmrqLFP 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 230 NLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLS---------LIIIMVITTLLTLFYYLRLTFAGFLFSYQETK 300
Cdd:PRK12646  384 KMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSqfslismiiIVFIGVIASIFTFTYALYMVKEVFWGKYDSKV 463
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-306 7.23e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 37.87  E-value: 7.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466   6 FSITLISGTLISISSSsWFGTWMGLEINLLSFIPLMTNTKNTLSTEASLKYFLIQALASSILLFSIIFM---------HL 76
Cdd:PRK06589  122 FNLTILIGVLIALSSD-LFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILiytktgnldFV 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466  77 SDMTLLLNQDLFLILISSPLLLKMGAAPFHFWFPGTM-----------------EGLSWVNCLILMTWQkiapFMLISYV 139
Cdd:PRK06589  201 SGGLFSKNQSIILLLMFIYGIAKTAIFPVHSWLPAAMvahypvsallhavivvkTGLFCIYKILLYIFG----LSYLQRI 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 140 IVMNTFIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMM--AALTTGENLWLFYFSIYTFLSTSIIFLFQSFQLF 217
Cdd:PRK06589  277 FAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALlsAFILTPKALGAAILHLVSHSFAKICLFYSMGSIY 356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 218 HLN-QNFLIKLN------PNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIM----VITTLLTLFYYLR 286
Cdd:PRK06589  357 SLKkEDQVDKLHgtsksfPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVmlvvIASSILSALYLLK 436

                         330       340
                  ....*....|....*....|
gi 1625655466 287 LTFAGFLFSYQETKWIENIP 306
Cdd:PRK06589  437 ILSSIYKPSLSENSFITKSL 456
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 145-287 9.35e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 37.82  E-value: 9.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1625655466 145 FIVLVITSSIIIGSLGGLNQTSLRKLMAYSSINHLGWMMAALTTGENLWL---FYFSIYTFLSTSIIFLFQSFQLFHLNQ 221
Cdd:PRK08377  275 LVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVdagVFHMINHAIVKALLFLAVGYVGITLGG 354

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1625655466 222 NFLIKLN------PNLKFCLFFLLLSLGGLPPFLGFLPKWLIIQALVDTNYLSLIIIMVITTLLTLFYYLRL 287
Cdd:PRK08377  355 TEIEKFEglgkrmPLTALALTIGALSTVGIPLFNVFWSKFRIILAGLSAGYTWPVALVLGASVVEAVYYFRL 426
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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