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Concise Results
Standard Results
Full Results
nuclear antigen EBNA-3A [human gammaherpesvirus 4]
Protein Classification
drebrin family protein ( domain architecture ID 11476234 )
drebrin family protein similar to the portion of Homo sapiens drebrin-like protein, an adapter protein that binds F-actin and DNM1, thus plays a role in receptor-mediated endocytosis
List of domain hits
Name
Accession
Description
Interval
E-value
PHA03379
PHA03379 EBNA-3A; Provisional
1-944
0e+00
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain]
Cd Length: 935
Bit Score: 1577.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 1 MDKDRPG P PA l D D NME EEVPSTS V VQEQ V S A GDWENVLIE L SDSSSE K EAEDAHLEP A QKG T KRKRVD H DAGGSAPA R P M 80
Cdd:PHA03379 1 MDKDRPG L PA - P D DNI EEVPSTS G VQEQ A S G GDWENVLIE D SDSSSE E EAEDAHLEP P QKG K KRKRVD D DAGGSAPA Q P P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 81 L PPQ P DLPGREAIL R RFPLDLR T LLQAIGAAAT RI DTRAIDQFFGSQISNT EM Y I MYAMAIRQAIRDRRRNPASRR D Q A K 160
Cdd:PHA03379 80 C PPQ L DLPGREAIL G RFPLDLR K LLQAIGAAAT HP DTRAIDQFFGSQISNT QR Y L MYAMAIRQAIRDRRRNPASRR C Q N K 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 161 WRL Q TLAAGWPMGYQAYSSWMYSYTD H Q T TPT FV HLQATLGC TG GRRCHVTFSAGTFKPPRC T PGDRQWLYVQS S VG NI V 240
Cdd:PHA03379 160 WRL T TLAAGWPMGYQAYSSWMYSYTD D Q R TPT RI HLQATLGC EE GRRCHVTFSAGTFKPPRC S PGDRQWLYVQS C VG EL V 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 241 QSCNP R YSIFFDYMAIHRSLTKIWEE I LTPDQRV S FMEFLGFLQRTDL S YIK N FVS D ALGTTSIQTPW I D D NPSTETAQA 320
Cdd:PHA03379 240 QSCNP I YSIFFDYMAIHRSLTKIWEE V LTPDQRV P FMEFLGFLQRTDL I YIK S FVS E ALGTTSIQTPW L D E NPSTETAQA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 321 WNAG F LRGRAYGLDLLRTEGEH V EGATGETREESED A ESDGDDE D LP C IVSR G G P K V KRPPIF I RRLHRLLLMRAGK R TE 400
Cdd:PHA03379 320 WNAG L LRGRAYGLDLLRTEGEH D EGATGETREESED T ESDGDDE E LP R IVSR E G T K R KRPPIF L RRLHRLLLMRAGK L TE 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 401 QGK E V LEKA RGS TYGTPR S PV P KPRPEVPQS D ETATSHGSAQVPEPP TI H LAAQ G M ayi LH E QH G MAPCPVAQ A PP T PL P 480
Cdd:PHA03379 400 RAR E A LEKA SEP TYGTPR P PV E KPRPEVPQS L ETATSHGSAQVPEPP PV H DLEP G P --- LH D QH S MAPCPVAQ L PP G PL Q 476
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 481 PVS PGDQLPGV SS DGR V ACAPVPAPAGPIVRPWE P SL T Q AA G Q AFAPV R PQ H MPVEPVPVPTVALER pvypk PV R PAPP K 560
Cdd:PHA03379 477 DLE PGDQLPGV VQ DGR P ACAPVPAPAGPIVRPWE A SL S Q VP G V AFAPV M PQ P MPVEPVPVPTVALER ----- PV C PAPP L 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 561 F AMQGPGETSGI R R A RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ VK QASVEVQP T QLTQVSPQQPME G PL V PEQQ 640
Cdd:PHA03379 552 I AMQGPGETSGI V R V RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ PY QASVEVQP P QLTQVSPQQPME Y PL E PEQQ 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 641 MFPG A PFSQVADV V RA P GVPAMQPQYFDLPL I QPISQGAP V APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 720
Cdd:PHA03379 632 MFPG S PFSQVADV M RA G GVPAMQPQYFDLPL Q QPISQGAP L APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 721 PQQPMEGPLVPERWMF P GA A LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 800
Cdd:PHA03379 712 PQQPMEGPLVPERWMF Q GA T LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 801 VQHQLDALGY A LH G LNHPGVPVSPAVNQYH L SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ E EGG 880
Cdd:PHA03379 792 VQHQLDALGY V LH V LNHPGVPVSPAVNQYH V SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ G EGG 871
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624813050 881 QDATEVLDLSIHGRPRPRTPEWPVQGE G GQNVTG P E T RRVVVSA V VHMCQDDEFPDLQDPPDEA 944
Cdd:PHA03379 872 QDATEVLDLSIHGRPRPRTPEWPVQGE D GQNVTG A E S RRVVVSA L VHMCQDDEFPDLQDPPDEA 935
Name
Accession
Description
Interval
E-value
PHA03379
PHA03379 EBNA-3A; Provisional
1-944
0e+00
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain]
Cd Length: 935
Bit Score: 1577.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 1 MDKDRPG P PA l D D NME EEVPSTS V VQEQ V S A GDWENVLIE L SDSSSE K EAEDAHLEP A QKG T KRKRVD H DAGGSAPA R P M 80
Cdd:PHA03379 1 MDKDRPG L PA - P D DNI EEVPSTS G VQEQ A S G GDWENVLIE D SDSSSE E EAEDAHLEP P QKG K KRKRVD D DAGGSAPA Q P P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 81 L PPQ P DLPGREAIL R RFPLDLR T LLQAIGAAAT RI DTRAIDQFFGSQISNT EM Y I MYAMAIRQAIRDRRRNPASRR D Q A K 160
Cdd:PHA03379 80 C PPQ L DLPGREAIL G RFPLDLR K LLQAIGAAAT HP DTRAIDQFFGSQISNT QR Y L MYAMAIRQAIRDRRRNPASRR C Q N K 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 161 WRL Q TLAAGWPMGYQAYSSWMYSYTD H Q T TPT FV HLQATLGC TG GRRCHVTFSAGTFKPPRC T PGDRQWLYVQS S VG NI V 240
Cdd:PHA03379 160 WRL T TLAAGWPMGYQAYSSWMYSYTD D Q R TPT RI HLQATLGC EE GRRCHVTFSAGTFKPPRC S PGDRQWLYVQS C VG EL V 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 241 QSCNP R YSIFFDYMAIHRSLTKIWEE I LTPDQRV S FMEFLGFLQRTDL S YIK N FVS D ALGTTSIQTPW I D D NPSTETAQA 320
Cdd:PHA03379 240 QSCNP I YSIFFDYMAIHRSLTKIWEE V LTPDQRV P FMEFLGFLQRTDL I YIK S FVS E ALGTTSIQTPW L D E NPSTETAQA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 321 WNAG F LRGRAYGLDLLRTEGEH V EGATGETREESED A ESDGDDE D LP C IVSR G G P K V KRPPIF I RRLHRLLLMRAGK R TE 400
Cdd:PHA03379 320 WNAG L LRGRAYGLDLLRTEGEH D EGATGETREESED T ESDGDDE E LP R IVSR E G T K R KRPPIF L RRLHRLLLMRAGK L TE 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 401 QGK E V LEKA RGS TYGTPR S PV P KPRPEVPQS D ETATSHGSAQVPEPP TI H LAAQ G M ayi LH E QH G MAPCPVAQ A PP T PL P 480
Cdd:PHA03379 400 RAR E A LEKA SEP TYGTPR P PV E KPRPEVPQS L ETATSHGSAQVPEPP PV H DLEP G P --- LH D QH S MAPCPVAQ L PP G PL Q 476
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 481 PVS PGDQLPGV SS DGR V ACAPVPAPAGPIVRPWE P SL T Q AA G Q AFAPV R PQ H MPVEPVPVPTVALER pvypk PV R PAPP K 560
Cdd:PHA03379 477 DLE PGDQLPGV VQ DGR P ACAPVPAPAGPIVRPWE A SL S Q VP G V AFAPV M PQ P MPVEPVPVPTVALER ----- PV C PAPP L 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 561 F AMQGPGETSGI R R A RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ VK QASVEVQP T QLTQVSPQQPME G PL V PEQQ 640
Cdd:PHA03379 552 I AMQGPGETSGI V R V RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ PY QASVEVQP P QLTQVSPQQPME Y PL E PEQQ 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 641 MFPG A PFSQVADV V RA P GVPAMQPQYFDLPL I QPISQGAP V APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 720
Cdd:PHA03379 632 MFPG S PFSQVADV M RA G GVPAMQPQYFDLPL Q QPISQGAP L APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 721 PQQPMEGPLVPERWMF P GA A LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 800
Cdd:PHA03379 712 PQQPMEGPLVPERWMF Q GA T LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 801 VQHQLDALGY A LH G LNHPGVPVSPAVNQYH L SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ E EGG 880
Cdd:PHA03379 792 VQHQLDALGY V LH V LNHPGVPVSPAVNQYH V SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ G EGG 871
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624813050 881 QDATEVLDLSIHGRPRPRTPEWPVQGE G GQNVTG P E T RRVVVSA V VHMCQDDEFPDLQDPPDEA 944
Cdd:PHA03379 872 QDATEVLDLSIHGRPRPRTPEWPVQGE D GQNVTG A E S RRVVVSA L VHMCQDDEFPDLQDPPDEA 935
EBV-NA3
pfam05009 Epstein-Barr virus nuclear antigen 3 (EBNA-3); This family contains EBNA-3A, -3B, and -3C ...
139-384
4.28e-141
Epstein-Barr virus nuclear antigen 3 (EBNA-3); This family contains EBNA-3A, -3B, and -3C which are latent infection nuclear proteins important for Epstein-Barr virus (EBV)-induced B-cell immortalization and the immune response to EBV infection.
Pssm-ID: 282817
Cd Length: 254
Bit Score: 420.51
E-value: 4.28e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 139 MAIRQ A I R D R RRNP A SR R DQ A KWRLQ T LAA G WPMGY QA YS S WMYSYTDHQTTPTFVHL Q ATLGCTGGRRCHVTFSAGTFK 218
Cdd:pfam05009 1 MAIRQ R I Q D I RRNP L SR V DQ R KWRLQ S LAA S WPMGY RT YS L WMYSYTDHQTTPTFVHL T ATLGCTGGRRCHVTFSAGTFK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 219 P PRCTPGD R QWLYVQSSV G NI V QSCNPRYSIFFD Y MAIHRSLTKIWEE I LTPD Q RVSFMEFLGFLQRTDLSYIK NFV SDA 298
Cdd:pfam05009 81 L PRCTPGD Q QWLYVQSSV R NI R QSCNPRYSIFFD L MAIHRSLTKIWEE L LTPD N RVSFMEFLGFLQRTDLSYIK SWF SDA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 299 LGTT S IQTPWID D NP ------ STETAQA W NA G FLRG R AYG L DLLRTEGE H VEGATGETREESED A ES DG DDE D LPCIV S R 372
Cdd:pfam05009 161 LGTT K IQTPWID A NP nenpyh STETAQA I NA A FLRG Q AYG I DLLRTEGE P VEGATGETREESED T ES ES DDE E LPCIV P R 240
250
....*....|..
gi 1624813050 373 GGP K VKRPPIFI 384
Cdd:pfam05009 241 GGP V VKRPPIFI 252
Name
Accession
Description
Interval
E-value
PHA03379
PHA03379 EBNA-3A; Provisional
1-944
0e+00
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain]
Cd Length: 935
Bit Score: 1577.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 1 MDKDRPG P PA l D D NME EEVPSTS V VQEQ V S A GDWENVLIE L SDSSSE K EAEDAHLEP A QKG T KRKRVD H DAGGSAPA R P M 80
Cdd:PHA03379 1 MDKDRPG L PA - P D DNI EEVPSTS G VQEQ A S G GDWENVLIE D SDSSSE E EAEDAHLEP P QKG K KRKRVD D DAGGSAPA Q P P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 81 L PPQ P DLPGREAIL R RFPLDLR T LLQAIGAAAT RI DTRAIDQFFGSQISNT EM Y I MYAMAIRQAIRDRRRNPASRR D Q A K 160
Cdd:PHA03379 80 C PPQ L DLPGREAIL G RFPLDLR K LLQAIGAAAT HP DTRAIDQFFGSQISNT QR Y L MYAMAIRQAIRDRRRNPASRR C Q N K 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 161 WRL Q TLAAGWPMGYQAYSSWMYSYTD H Q T TPT FV HLQATLGC TG GRRCHVTFSAGTFKPPRC T PGDRQWLYVQS S VG NI V 240
Cdd:PHA03379 160 WRL T TLAAGWPMGYQAYSSWMYSYTD D Q R TPT RI HLQATLGC EE GRRCHVTFSAGTFKPPRC S PGDRQWLYVQS C VG EL V 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 241 QSCNP R YSIFFDYMAIHRSLTKIWEE I LTPDQRV S FMEFLGFLQRTDL S YIK N FVS D ALGTTSIQTPW I D D NPSTETAQA 320
Cdd:PHA03379 240 QSCNP I YSIFFDYMAIHRSLTKIWEE V LTPDQRV P FMEFLGFLQRTDL I YIK S FVS E ALGTTSIQTPW L D E NPSTETAQA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 321 WNAG F LRGRAYGLDLLRTEGEH V EGATGETREESED A ESDGDDE D LP C IVSR G G P K V KRPPIF I RRLHRLLLMRAGK R TE 400
Cdd:PHA03379 320 WNAG L LRGRAYGLDLLRTEGEH D EGATGETREESED T ESDGDDE E LP R IVSR E G T K R KRPPIF L RRLHRLLLMRAGK L TE 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 401 QGK E V LEKA RGS TYGTPR S PV P KPRPEVPQS D ETATSHGSAQVPEPP TI H LAAQ G M ayi LH E QH G MAPCPVAQ A PP T PL P 480
Cdd:PHA03379 400 RAR E A LEKA SEP TYGTPR P PV E KPRPEVPQS L ETATSHGSAQVPEPP PV H DLEP G P --- LH D QH S MAPCPVAQ L PP G PL Q 476
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 481 PVS PGDQLPGV SS DGR V ACAPVPAPAGPIVRPWE P SL T Q AA G Q AFAPV R PQ H MPVEPVPVPTVALER pvypk PV R PAPP K 560
Cdd:PHA03379 477 DLE PGDQLPGV VQ DGR P ACAPVPAPAGPIVRPWE A SL S Q VP G V AFAPV M PQ P MPVEPVPVPTVALER ----- PV C PAPP L 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 561 F AMQGPGETSGI R R A RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ VK QASVEVQP T QLTQVSPQQPME G PL V PEQQ 640
Cdd:PHA03379 552 I AMQGPGETSGI V R V RERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQ PY QASVEVQP P QLTQVSPQQPME Y PL E PEQQ 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 641 MFPG A PFSQVADV V RA P GVPAMQPQYFDLPL I QPISQGAP V APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 720
Cdd:PHA03379 632 MFPG S PFSQVADV M RA G GVPAMQPQYFDLPL Q QPISQGAP L APLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 721 PQQPMEGPLVPERWMF P GA A LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 800
Cdd:PHA03379 712 PQQPMEGPLVPERWMF Q GA T LSQSVRPGVAQSQYFDLPLTQPINHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDV 791
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 801 VQHQLDALGY A LH G LNHPGVPVSPAVNQYH L SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ E EGG 880
Cdd:PHA03379 792 VQHQLDALGY V LH V LNHPGVPVSPAVNQYH V SQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQ G EGG 871
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624813050 881 QDATEVLDLSIHGRPRPRTPEWPVQGE G GQNVTG P E T RRVVVSA V VHMCQDDEFPDLQDPPDEA 944
Cdd:PHA03379 872 QDATEVLDLSIHGRPRPRTPEWPVQGE D GQNVTG A E S RRVVVSA L VHMCQDDEFPDLQDPPDEA 935
EBV-NA3
pfam05009 Epstein-Barr virus nuclear antigen 3 (EBNA-3); This family contains EBNA-3A, -3B, and -3C ...
139-384
4.28e-141
Epstein-Barr virus nuclear antigen 3 (EBNA-3); This family contains EBNA-3A, -3B, and -3C which are latent infection nuclear proteins important for Epstein-Barr virus (EBV)-induced B-cell immortalization and the immune response to EBV infection.
Pssm-ID: 282817
Cd Length: 254
Bit Score: 420.51
E-value: 4.28e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 139 MAIRQ A I R D R RRNP A SR R DQ A KWRLQ T LAA G WPMGY QA YS S WMYSYTDHQTTPTFVHL Q ATLGCTGGRRCHVTFSAGTFK 218
Cdd:pfam05009 1 MAIRQ R I Q D I RRNP L SR V DQ R KWRLQ S LAA S WPMGY RT YS L WMYSYTDHQTTPTFVHL T ATLGCTGGRRCHVTFSAGTFK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 219 P PRCTPGD R QWLYVQSSV G NI V QSCNPRYSIFFD Y MAIHRSLTKIWEE I LTPD Q RVSFMEFLGFLQRTDLSYIK NFV SDA 298
Cdd:pfam05009 81 L PRCTPGD Q QWLYVQSSV R NI R QSCNPRYSIFFD L MAIHRSLTKIWEE L LTPD N RVSFMEFLGFLQRTDLSYIK SWF SDA 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 299 LGTT S IQTPWID D NP ------ STETAQA W NA G FLRG R AYG L DLLRTEGE H VEGATGETREESED A ES DG DDE D LPCIV S R 372
Cdd:pfam05009 161 LGTT K IQTPWID A NP nenpyh STETAQA I NA A FLRG Q AYG I DLLRTEGE P VEGATGETREESED T ES ES DDE E LPCIV P R 240
250
....*....|..
gi 1624813050 373 GGP K VKRPPIFI 384
Cdd:pfam05009 241 GGP V VKRPPIFI 252
PHA03378
PHA03378 EBNA-3B; Provisional
116-772
1.14e-25
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain]
Cd Length: 991
Bit Score: 114.39
E-value: 1.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 116 D T R AIDQF F GS Q IS N T E MY I MYA M AI R QAIRDR R RN P ASRRD Q AK W R L QTLAAG W P MGY QAYSSWMY S YTDHQTTPTF V H 195
Cdd:PHA03378 122 D L R HLGSL F LE Q NL N I E EF I WMC M TV R HRCQAI R EK P LPIAK Q RR W K L LSPQRT W R MGY RTRHLMVN S FELGGDSVHP V L 201
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 196 LQ ATLGC TG G R R CH VT F SAG TFK PPR CTPGDRQWLYVQSSVGNIVQSCNP RY SI FFD YMAIHRS L TK IW EEIL T PD q RV S 275
Cdd:PHA03378 202 VT ATLGC EE G E R HA VT Y SAG IVQ PPR MSDQNQKIETAFLMARRARSLSAE RY TL FFD LVSSGNT L YA IW IGLG T RN - RV A 280
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 276 F M EF L G F L QRT D LSY I KNFVSDAL G TTSIQT PW IDDN P ------ STE T AQAWNAGFL RG R A YGLDLL R TEGEHVEGATGE 349
Cdd:PHA03378 281 F V EF V G W L CKK D HTH I REWFRQCT G RPRPTK PW LRAH P vavpyd DPL T SEEIDLAYA RG L A MEIEAV R LPDDPIIVEDDD 360
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 350 TR EE S E D a E S D G D DED -------- L P CIVSRGGPKVK RP PI F irrlhrl LLMRAG K R T EQGKEVL ---------- E KA R G 411
Cdd:PHA03378 361 ES EE I E S - E C D P D EDK sgaealas I P QTLPDPPTVYG RP KV F ------- ARKADL K S T KKCRAIV tdpsvikaie E EH R K 432
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 412 STYGTPRS P VPK P RPEV P --------- Q SD E TA T SHG S A Q --- V P EP P TI H L aa Q GMAY ILH ------------------ 461
Cdd:PHA03378 433 KKAARTEQ P RAT P HSQA P tvvlhrppt Q PL E GP T GPL S V Q apl E P WQ P LP H P -- Q VTPV ILH qppaqgvqahgsmldlle 510
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 462 ------ EQ HG M ---------------- APC PVAQ ---- APPT P LPPVSPG DQL PGVSSD G RVACA P VPA P AGPIVRPWE P 515
Cdd:PHA03378 511 kddedm EQ RV M atllppsppqpragrr APC VYTE dldi ESDE P ASTEPVH DQL LPAPGL G PLQIQ P LTS P TTSQLASSA P 590
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 516 S LT Q AAGQAFA P vr P Q HMPVEPVPVPTVALER P - VY P K P V RP A P PKFAMQG P GETSGIRRARERWR P ---- A P WT P N --- 587
Cdd:PHA03378 591 S YA Q TPWPVPH P -- S Q TPEPPTTQSHIPETSA P r QW P M P L RP I P MRPLRMQ P ITFNVLVFPTPHQP P qvei T P YK P T wtq 668
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 588 PPRS P S Q M S VRDRLAR L RAEA qv KQASVEVQ P TQL T QVS P QQPME G PLVPEQQMFPG A PFSQV A DVVRA P -- GV P AMQPQ 665
Cdd:PHA03378 669 IGHI P Y Q P S PTGANTM L PIQW -- APGTMQPP P RAP T PMR P PAAPP G RAQRPAAATGR A RPPAA A PGRAR P pa AA P GRARP 746
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 666 YFDL P LIQPISQG AP VAPLRASMG P VP P V P ATQ PQ YFDI P LTE P in Q GA SA ahfl PQ Q P MEGPLVPERW M FPG A ALS Q S v 745
Cdd:PHA03378 747 PAAA P GRARPPAA AP GRARPPAAA P GA P T P QPP PQ APPA P QQR P -- R GA PT ---- PQ P P PQAGPTSMQL M PRA A PGQ Q G - 819
730 740
....*....|....*....|....*..
gi 1624813050 746 rpgv AQS Q YFDLP LT QPINH G A P AAHF 772
Cdd:PHA03378 820 ---- PTK Q ILRQL LT GGVKR G R P SLKK 842
PHA03377
PHA03377 EBNA-3C; Provisional
98-807
2.05e-18
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain]
Cd Length: 1000
Bit Score: 90.88
E-value: 2.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 98 P LDL R TLLQ A IGA A ATRIDTR A IDQFFGSQISN T EMYIMYA MA I RQ AIR D R RR N P ASRRDQAK WR --- L QTLAAG W P MGY 174
Cdd:PHA03377 105 P YSA R NIRD A ACE A VKQSHLQ A LSNLILDSGLD T QHMLCFV MA A RQ RLQ D I RR G P LVAEGGVG WR hwl L TSPSVS W Y MGY 184
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 175 QAYSSWMYSYTDHQTTPTFVH L Q AT L GC TG G R R CHV TFSA GTFK PP RCT P GDRQWLYVQSS V GNIVQSCNP RY SIF FD YM 254
Cdd:PHA03377 185 RTATLRTLTPVPNRVGADSIM L T AT F GC QN G A R NEN TFSA TVWT PP LAG P REQERYAREAE V RFLRGKWQR RY RRI FD LI 264
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 255 AIHR SL TK IW EEI L - T PDQRVS F ME F L G FLQRTDLSYIKNFVSDAL G TTSIQT PW id DN P ST E TA --------- QAWNAG 324
Cdd:PHA03377 265 ELCG SL HH IW QNR L q T EENLLD F VR F M G VMSSCNNPAVNYWFHKTI G NFKPYY PW -- NA P PN E NP yharrgike DVIQTA 342
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 325 F LRGRAY GL DL L R T E GE HVEG AT G ET REESE ------ D A E SDGD D ED LP C I VSRGG P KVK RP PI F IR R LHRLLLMR --- A 395
Cdd:PHA03377 343 F RKAQRQ GL SM L A T G GE PRGD AT S ET SSDED tgrqgs D V E LESS D DE LP Y I DPNME P VQQ RP VM F VS R VPWRKPRT lpw P 422
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 396 GKR T EQG K EV L E K AR G ST ------ YG TP RS P V P KPR P E VP Q sdetatshgsaqvp EP P ti HL AAQGMAYILHE Q HGMA P C 469
Cdd:PHA03377 423 TPK T HPV K RT L V K TS G RS deaeqa QS TP ER P G P SDQ P S VP V -------------- EP A -- HL TPVEHTTVILH Q PPQS P P 486
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 470 P VA QA P P tplppvspgdql P GV S SDG R V AC A pvp APAGP I VRPWEPSL T QAAGQAFA P VR P QHMPVEPVPVPTVALE R PV 549
Cdd:PHA03377 487 T VA IK P A ------------ P PP S RRR R G AC V --- VYDDD I IEVIDVET T EEEESVTQ P AK P HRKVQDGFQRSGRRQK R AT 551
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 550 Y P -- K P VRPA PPK FAMQGPGET S GIR R ARERWRPA P WTPN PP RSPSQMSVRDRLARLRAEAQV KQ ---- A SVEVQ P TQLT 623
Cdd:PHA03377 552 P P kv S P SDRG PPK ASPPVMAPP S TGP R VMATPSTG P RDMA PP STGPRQQAKCKDGPPASGPHE KQ ppss A PRDMA P SVVR 631
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 624 QVSPQQPM E GPLV P EQQM F PGAPFSQVADVVRAP gv P AMQ pqyfdlpl I QP IS Q GA P VA P LRA - S MGPV P P V P A TQP Q YF 702
Cdd:PHA03377 632 MFLRERLL E QSTG P KPKS F WEMRAGRDGSGIQQE -- P SSR -------- R QP AT Q ST P PR P SWL p S VFVL P S V D A GRA Q PS 701
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 703 DI ---- PL -- T E PI NQGASAAHFL P QQ P MEGP L V P ERWMF P G aal S Q SVRP G vaqsq YFDLPLT Q pinhg AP AAHFLHQP 776
Cdd:PHA03377 702 EE shls SM sp T Q PI SHEEQPRYED P DD P LDLS L H P DQAPP P S --- H Q APYS G ----- HEEPQAQ Q ----- AP YPGYWEPR 768
730 740 750
....*....|....*....|....*....|.
gi 1624813050 777 P MEG P WVPE Q wmfqg A P PS QG TD V VQHQLD A 807
Cdd:PHA03377 769 P PQA P YLGY Q ----- E P QA QG VQ V SSYPGY A 794
PHA03247
PHA03247 large tegument protein UL36; Provisional
407-888
1.40e-09
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 62.65
E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 407 E K A RG S TYGT P RS P VPKP RP EV P QS D ETATSHGSAQV P E PP TI H laaqgmayilheqhgm AP C P VAQA P PTPLPPVS P GD 486
Cdd:PHA03247 2579 E P A VT S RARR P DA P PQSA RP RA P VD D RGDPRGPAPPS P L PP DT H ---------------- AP D P PPPS P SPAANEPD P HP 2642
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 487 QLPGVSSD grvac A P VPA PA GPI V RPWE -- PS L TQ AA GQAFA P V RP QHMPVE P VPVPTVA L ER P VY P K P VRPAP P KFAMQ 564
Cdd:PHA03247 2643 PPTVPPPE ----- R P RDD PA PGR V SRPR ra RR L GR AA QASSP P Q RP RRRAAR P TVGSLTS L AD P PP P P P TPEPA P HALVS 2717
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 565 GPGETS G IRR AR ERWRPA P WT P N PP RS P SQ msvrdrlarlr AEAQVKQ A SVEVQ PT QLTQVS P QQ P MEGPLV P EQQM -- F 642
Cdd:PHA03247 2718 ATPLPP G PAA AR QASPAL P AA P A PP AV P AG ----------- PATPGGP A RPARP PT TAGPPA P AP P AAPAAG P PRRL tr P 2786
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 643 PG A PF S QVADVVRA P GV PA MQ P QYFDL P LIQPISQGA P VA PL RASMGPV P PV P ATQ P QYF di P LTE P INQGASAAHFLPQ 722
Cdd:PHA03247 2787 AV A SL S ESRESLPS P WD PA DP P AAVLA P AAALPPAAS P AG PL PPPTSAQ P TA P PPP P GPP -- P PSL P LGGSVAPGGDVRR 2864
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 723 Q P MEGPLVPERWMFPGAALSQSV RP G V AQ S - QY F D LP LT QP INHGA P A A hfl HQ PP MEG P WV P EQWMF Q GA PP SQG ---- 797
Cdd:PHA03247 2865 R P PSRSPAAKPAAPARPPVRRLA RP A V SR S t ES F A LP PD QP ERPPQ P Q A --- PP PP QPQ P QP P PPPQP Q PP PP PPP rpqp 2941
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 798 ---- T DVVQHQLDAL G YALHGLNHPG VP VSP AV NQYHLS Q A A FGLPIDEDESGEGSDT S EP --- CE A LD L SI H GRPC P QA 870
Cdd:PHA03247 2942 plap T TDPAGAGEPS G AVPQPWLGAL VP GRV AV PRFRVP Q P A PSREAPASSTPPLTGH S LS rvs SW A SS L AL H EETD P PP 3021
490 500
....*....|....*....|...
gi 1624813050 871 PE ----- WP VQEEGGQ DA TEVL D 888
Cdd:PHA03247 3022 VS lkqtl WP PDDTEDS DA DSLF D 3044
PAT1
pfam09770 Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
581-784
8.49e-06
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain]
Cd Length: 846
Bit Score: 49.65
E-value: 8.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 581 PAPWT P N P PRS P SQ -------- MS VRDRL A RL RA E A QVKQA svev QP TQLTQVS P QQ P megplv P E QQ MFPGAP F SQ vad 652
Cdd:pfam09770 172 APAPA P Q P AAQ P AS lpapsrkm MS LEEVE A AM RA Q A KKPAQ ---- QP APAPAQP P AA P ------ P A QQ AQQQQQ F PP --- 238
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 653 vvra PGVPAM QPQ YFDLPLI Q PIS QG A PV AP L R -- A S MG P V P PV P AT QPQ yfdipltepinqgasa A HFLP QQP megplv 730
Cdd:pfam09770 239 ---- QIQQQQ QPQ QQPQQPQ Q HPG QG H PV TI L Q rp Q S PQ P D P AQ P SI QPQ ---------------- A QQFH QQP ------ 292
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1624813050 731 P ERWMF P GAA L SQSV R PGV A QSQ Y FDL P lt QP INHG APA AHFLH Q PPME G PWV P 784
Cdd:pfam09770 293 P PVPVQ P TQI L QNPN R LSA A RVG Y PQN P -- QP GVQP APA HQAHR Q QGSF G RQA P 344
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
559-786
6.34e-03
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 40.52
E-value: 6.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 559 P KFAMQ G P GE T S GI R RARERWRPA P W --- TP N PPR SPS QM S VR D RLARLRAE AQ VKQASVE v Q P TQLT Q VSPQQ P MEG P L 635
Cdd:pfam03154 110 P NSPSE G E GE S S DG R SVNDEGSSD P K did QD N RST SPS IP S PQ D NESDSDSS AQ QQILQTQ - P P VLQA Q SGAAS P PSP P P 188
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624813050 636 VPEQ Q MFPGA P FSQVAD V VRAPGVPAM QP QYFDLPLIQ P --- I S Q GAPVA P L R ASMGPV P PV P A TQP Q yfd I P LTEPINQ 712
Cdd:pfam03154 189 PGTT Q AATAG P TPSAPS V PPQGSPATS QP PNQTQSTAA P htl I Q Q TPTLH P Q R LPSPHP P LQ P M TQP P --- P P SQVSPQP 265
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624813050 713 GASAAHFLPQQ PM EGP L V -- P ERWMF P GAALSQSVR P GVA QSQ YFDL P LTQP inh GAPAAHFL H Q PP MEGPWVPE Q 786
Cdd:pfam03154 266 LPQPSLHGQMP PM PHS L Q tg P SHMQH P VPPQPFPLT P QSS QSQ VPPG P SPAA --- PGQSQQRI H T PP SQSQLQSQ Q 338
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
