|
Name |
Accession |
Description |
Interval |
E-value |
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
59-566 |
1.59e-172 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 498.53 E-value: 1.59e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 59 DPESWLMYGGSYEQHRATPADVITPENVADLELEYELSVGT--GSSMEGTPIVVPGdppVMYQTNGPNHMKAIDPREGEI 136
Cdd:COG4993 1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDlpERGHEATPLVVDG---VLYVCTPHNRVFALDAATGKE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 137 LWSYTYAVPMGVeLCCDDNNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAPVVHDGTIYTGSA 216
Cdd:COG4993 78 LWRYDPKLPDDA-ACCDVVNRGVAYYDGRIFLGTLDGRLVALDAKTGKVCWDVKVGDPKKGYTITSAPLVVKDKVIVGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 217 GGEYGVLGFIAAIDAESGEIQWQTDT------LLEDEW-VGASREHGCGTSWMTPTIDEEAGVLYTAVANPGPDFDGTVR 289
Cdd:COG4993 157 GGEFGPRGVVRAYDARTGKLVWRFDTipdpgePGAETWpPGDTWKRGGGNVWGTMSYDPELGLVYLPTGNPAPDWNGGQR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 290 PGPNFPTCGTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVVGSDKTGWVYMMDAESGDL----- 364
Cdd:COG4993 237 PGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILV-DLPVDGKTRKALVQATKNGFIYVLDRETGEPlvtqp 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 365 HERSEEICQHINMWEMIPHI----SEDERVPFVPGAPGGNDWQPPSYNPETGLVYVIHQNYPQDLYWRYEEFSEGNPYWG 440
Cdd:COG4993 316 FVKPPNWATEIDMWGATPIQtppsLDGKTTLICPGALGGKNWGPAAYDPETGLLYVPANELCMDYELVPREYQAGAPYLG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 441 GGLADPAsefpdEWNGAITAFAAVDPTTGERVWRewieSEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEY 520
Cdd:COG4993 396 ATLTMYP-----CPAPPWGTLTAIDLNTGKIVWQ----VPLGFPNWGGPLATAGGLVFIGTLDGYLRAFDAKTGKELWKF 466
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1621087063 521 EFDVPISASPMSWYdpDEGKQYVAVQVGGSGWLRQG---PRGDTLAVFS 566
Cdd:COG4993 467 RLPSGGQATPMTYE--VDGKQYVAVAAGGGGWLGLGlytPQGDYLIAFA 513
|
|
| PQQ_ADH_I |
cd10277 |
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ... |
59-567 |
1.79e-129 |
|
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.
Pssm-ID: 199835 [Multi-domain] Cd Length: 529 Bit Score: 388.96 E-value: 1.79e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 59 DPESWLMYGGSYEQHRATPADVITPENVADLELEYELSVGTGS-SMEGTPIVVPGdppVMYQTNGPNHMKAIDPREGEIL 137
Cdd:cd10277 7 ETGNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGGKQrGQESQPIVNDG---VMYVTTSYNRVFAIDAKTGKEL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 138 WSYTYAVPMGVELCCDDNNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAPVVHDGTIYTGSAG 217
Cdd:cd10277 84 WKYKHRLPEDIRPCCDVVNRGVALYGDKVYFGTLDAHLVALDAKTGKVVWKKKVADYKAGYSMTLAPLVVKGKVIVGVSG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 218 GEYGVLGFIAAIDAESGEIQWQTDT-------LLEDEWVGASREHGCGTSWMTPTIDEEAGVLYTAVANPGPDFDGtVRP 290
Cdd:cd10277 164 GEFGVRGFIAALDAETGKEVWRTYTvpgpgepGSTDTWPGDAWKTGGGATWLTGTYDPETNLLYWGVGNPAPWNGD-LRP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 291 GPNFPTCGTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVVGSDKTGWVYMMDAESGDLHeRSEE 370
Cdd:cd10277 243 GDNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEPVLF-DYTKNGKPVKALVHADRNGFFYVLDRTNGKLI-WATP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 371 ICQHINMWEMIPH----ISEDERVP--------FVPGAPGGNDWQPPSYNPETGLVYVIHQNYPQDLYWRYEEFSEGNPY 438
Cdd:cd10277 321 FVKKITWASIDLKtgrpIYDEDKVPpkkgktvdFCPSFLGGKNWPPMAYSPDTGLFYVPANHWCMDLTGEPVSYKKGAAY 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 439 WGGGLADPASeFPDEWnGAITAFaavDPTTGERVWREWIESEddhyMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLW 518
Cdd:cd10277 401 LGAGFTIKPP-FEDHI-GELQAI---DPTTGKKVWEHKTPLP----LWGGVLTTAGGLVFTGTPDGYFRAFDAKTGKELW 471
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 519 EYEFDVPISASPMSWydPDEGKQYVAVQVGGSGW-----------LRQGPRGDTLAVFSM 567
Cdd:cd10277 472 EFQTGSGIIGPPVTW--EVDGKQYVAVLSGWGGAaplwggdmaklLKNVPQGGSLWVFAL 529
|
|
| PQQ_enz_alc_DH |
TIGR03075 |
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ... |
47-551 |
2.17e-121 |
|
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.
Pssm-ID: 274419 [Multi-domain] Cd Length: 527 Bit Score: 368.16 E-value: 2.17e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 47 DVDQEMLSDTGEDPESWLMYGGSYEQHRATPADVITPENVADLELEYELSVGTGSSMEGTPIVVPGdppVMYQTNGPNHM 126
Cdd:TIGR03075 5 AVTNEDLLNDAKDPSDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLGKQRGQESQPLVVDG---VMYVTTSYSRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 127 KAIDPREGEILWSYTYAVPMGV--ELCCDDNNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAP 204
Cdd:TIGR03075 82 YALDAKTGKILWKYDPKLPDDIipVMCCDVVNRGAALYDGKVFFGTLDARLVALDAKTGKVVWSKKNGDYKKGYTITAAP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 205 VVHDGTIYTGSAGGEYGVLGFIAAIDAESGEIQWQT------DTLLE------------DEWVGASREHGCGTSWMTPTI 266
Cdd:TIGR03075 162 LVVKGKVITGISGGEFGVRGYVTAYDAKTGKLVWRRytvpgdMGYLKktgkpvggdpgaKTWPGDAWKTGGGATWGTGSY 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 267 DEEAGVLYTAVANPGPdFDGTVRPGPNFPTCGTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVV 346
Cdd:TIGR03075 242 DPETNLIYFGTGNPAP-WNSHLRPGDNLYTSSIVARDPDTGKIKWHYQTTPHDEWDYDGVNEMILF-DLKKDGKPRKLLA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 347 GSDKTGWVYMMDAESGDL-----HERSEEICQHINMWEMIPHISEDER---------VPFVPGAPGGNDWQPPSYNPETG 412
Cdd:TIGR03075 320 HADRNGFFYVLDRTNGKLlsaepFVDKVNWATGVDLKTGRPIEVPEARstdgkkgkpVEVCPGFLGGKNWQPMAYSPKTG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 413 LVYVIHQNYPQDlYWRYE-EFSEGNPYWGGGL-ADPASEfpdewnGAITAFAAVDPTTGERVWrewiESEDDHYMWGGSL 490
Cdd:TIGR03075 400 LFYVPANHVCMD-YWPEKvSYKKGAAYLGAGFtIKPPPD------DHIGSLIAWDPITGKIVW----EHKEDFPLWGGVL 468
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1621087063 491 STATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSWydPDEGKQYVAVQVGGSG 551
Cdd:TIGR03075 469 ATAGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTY--EQDGKQYVAVLSGWGG 527
|
|
| PQQ_ADH_II |
cd10279 |
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ... |
61-560 |
3.40e-100 |
|
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199837 [Multi-domain] Cd Length: 549 Bit Score: 314.20 E-value: 3.40e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 61 ESWLMYGGSYEQHRATPADVITPENVADLELEYELSVGTGSSMEGTPIVVPGdppVMYQTNGPNHMKAIDPREGEILWSY 140
Cdd:cd10279 1 GNWLSYGRDYDEQRFSPLTQINRSNVGQLGLAWYFDLDTNRGQEATPLVVDG---VMYVSGPWSVVYALDARTGKLLWQY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 141 TYAVPM--GVELCCDDNNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAPVVHDGTIYTGSAGG 218
Cdd:cd10279 78 DPEVDResGRKACCDVVNRGVAVWDGKVFVGTLDGRLIALDAKTGKEVWSVDTIDPRKPYTITGAPRVAKGKVVIGNGGA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 219 EYGVLGFIAAIDAESGEIQWQTDTL-----LEDE-----------WVGASREHGCG-TSWMTPTIDEEAGVLYTAVANPG 281
Cdd:cd10279 158 EFGVRGYVSAYDAETGKLVWRFYTVpgnpaKPFEhasleaaaatwWTGEWWRTGGGgTVWDSITYDPELDLLYIGTGNGS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 282 PdFDGTVRP---GPNFPTCGTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVVGSDKTGWVYMMD 358
Cdd:cd10279 238 P-WNRKVRSpggGDNLFLSSIVALDADTGRYKWHYQTTPGDTWDYTATQPIILA-DLEIDGKPRKVLMHAPKNGFFYVLD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 359 AESGDLHeRSEEICQ-----HINMWEMIPHISEDERV---PFV--PGAPGGNDWQPPSYNPETGLVY-------VIHQNY 421
Cdd:cd10279 316 RATGKLL-SAEPFVPvnwatGIDLKTGRPIENPEARYtkgPKLvfPGPLGAHNWHPMSYNPDTGLVYipaqeipAVYEDD 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 422 PQDlyWRYEEFSE--GNPYWGGGL-ADPASEFPDEWNGAITAFaavDPTTGERVWRewieSEDDHYMWGGSLSTATGLVF 498
Cdd:cd10279 395 PGD--FGYNPLGWntGITPDATPPpAAAKRALRKATRGRLVAW---DPVTQKAAWR----VEHPGPWNGGVLATAGNLVF 465
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1621087063 499 NGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSwYDPDeGKQYVAVQV--GGSGWLRQGPRGD 560
Cdd:cd10279 466 QGTADGELAAYDARTGEKLWSFDTGSGIVAAPMT-YSVD-GEQYVAVLAgwGGAGALSGGPPGA 527
|
|
| PQQ_MDH |
cd10278 |
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ... |
63-552 |
1.45e-93 |
|
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.
Pssm-ID: 199836 [Multi-domain] Cd Length: 553 Bit Score: 296.93 E-value: 1.45e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 63 WLMYGGSYEQHRATPADVITPENVADLELEYELSVGTGSSMEGTPIVVPGdppVMY-QTNGPNHMKAID-PREGEILWSY 140
Cdd:cd10278 1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLRGHEGAPLVVGD---TMYvVTPFPNNVYALDlNDPGKILWKY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 141 T-----YAVPMgveLCCDDNNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAPVVHDGTIYTGS 215
Cdd:cd10278 78 KpkqdpSAVAV---ACCDVVNRGLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDKVIVGI 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 216 AGGEYGVLGFIAAIDAESGEIQWQT-------DTLLEDE-----------------WVGASREHGCGTSWMTPTIDEEAG 271
Cdd:cd10278 155 SGGEFGVRGYVTAYDLKTGKLVWRAystgpdkDVLIGPDfnpfnphdggkdlglstWPGDAWKIGGGTNWGWYSYDPKLN 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 272 VLYTAVANPGPdFDGTVRPGPNFPTCGTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVVGSDKT 351
Cdd:cd10278 235 LVYYGTGNPGP-WNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILV-DQTVDGKKRKLLVHFDRN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 352 GWVYMMDAESGDLheRSEEICQHINMWEMI------PHISEdERVPFV--------PGAPGGNDWQPPSYNPETGLVYVI 417
Cdd:cd10278 313 GFVYTLDRTTGEL--LSAEKFDPVNNWKGVdlktgrPVKDP-EKSTHMdhnvtdicPSAMGGKDQQPSSYSPKTGLFYVP 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 418 HQNYPQDlywrYEEF----SEGNPYWGGGLAdpasEFPDEwNGAITAFAAVDPTTGERVWrewiESEDDHYMWGGSLSTA 493
Cdd:cd10278 390 TNHLCMD----YEPFevnyTAGQPYVGATLA----MYPGP-GGHMGQFKAWDPVTGKTKW----EIKERFPVWSGTLATA 456
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 1621087063 494 TGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSWydPDEGKQYVAVQVGGSGW 552
Cdd:cd10278 457 GGLVFYGTLDGWFKAVDAKTGKLLWKFKLPSGIIGNPITY--KHDGKQYVAVLSGVGGW 513
|
|
| PQQ_DH_like |
cd00216 |
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ... |
84-563 |
1.72e-72 |
|
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.
Pssm-ID: 199833 [Multi-domain] Cd Length: 434 Bit Score: 238.28 E-value: 1.72e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 84 ENVADLELEYELSVGTGSSM--EGTPIVVPGdppVMYQTNGPNHMKAIDPREGEILWSYTYAVPMG-VELCCDDNNRGAA 160
Cdd:cd00216 2 DNVFQLTPAWSFSTGDGGNRgsELTPIVVDG---VMYATTSFSRVFALDADDGKEIWSYDPALKDGwFEACCDLVNRGVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 161 VHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATWAPVVHDGTIYTGSAGGEYGVLGFIAAIDAESGEIQWQT 240
Cdd:cd00216 79 VWGGKVYIGVLDGRVYALNAETGKVAWKVKNADVLGGYTATSAPVVVDGLVIIGSSGDEFGVRGYLTAYDVATGEEKWRF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 241 DTLLED-----------------EWVGASREHGCGTSWMTPTIDEEAGVLYTAVANPGP-DFDGTVRPGPNFPTCGTISL 302
Cdd:cd00216 159 YLVMPDpnllpgkdstvtdrntpTGDEHTWTSGGGTGWSSAAYDAELNLIYVGGGNPTPwNWGGNRTPGDNLYTSSIVAV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 303 DLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDGSMDMVVGSDKTGWVYMMDAESGDLherseeicqhinMWEmip 382
Cdd:cd00216 239 NADTGEMKWQYQTTPHDAWDYDGDNTPVLA-DIKVKGKKVKVLFAPAKNGNFYVLDRRNGEL------------VSA--- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 383 hisedervpfvpgAPGGNDwqppSYNPETGLVYVihqnyPQdlywryeefsegnpywgggladpasefpdewNGAITAFa 462
Cdd:cd00216 303 -------------RPLVPD----SYDPDRELFYV-----PA-------------------------------NGRIMAL- 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 463 avDPTTGERVWrewiESEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSWydPDEGKQY 542
Cdd:cd00216 329 --DPVTGVVVW----EKSELHPLLGGPLSTAGNLVFVGTSDGYLKAYNADTGEKLWQQKVPSGFQAEPVTY--EVDGEQY 400
|
490 500
....*....|....*....|.
gi 1621087063 543 VAVQVGGSGWLRQGPRGDTLA 563
Cdd:cd00216 401 VLIQAGGGGAFPLWGGMADLT 421
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
63-565 |
1.04e-56 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 200.88 E-value: 1.04e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 63 WLMYGGSYEQHRATPADVITPENVADLEL-------EYELSVGTGSSMEGTPIVVPGdppVMYQTNGPNHMKAIDPREGE 135
Cdd:cd10280 1 WPAYGGDPGGTRYSPLDQITPDNVGKLKVawtyhtgDLPGPDGNEGTFEATPLKVGG---TLYLCTPHNRVIALDAATGK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 136 ILWSY---TYAVPMGVELCCddnnRGAAVHGDT---------VYMTTLDSGVVALDRYTGEE-------------RWYTS 190
Cdd:cd10280 78 ELWRFdpkAGADAAPGHQTC----RGVSYWEDGaaaaacarrIFFGTGDARLIALDARTGKPcpdfgdngvvdlrEGLGR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 191 TADHEegYSATWAPVVHDGTIYTGSAGGEYGVL----GFIAAIDAESGEIQWQTDTLLED-----EWVGASREHGCGTSW 261
Cdd:cd10280 154 VKPGF--YSSTSPPTVYGDLVIVGSAVADNQAVdapsGVIRAFDVRTGKLVWAFDTIPPPgeagpDTAGAWYTRGGPNVW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 262 MTPTIDEEAGVLYTAVANPGPDFDGTVRPGPN-FPTCgTISLDLESGEFQWGFQSSPHDVWDYDAVAPRVLVrDVETDDG 340
Cdd:cd10280 232 AGMSADEKLGLVYLPTGSATPDFYGGDRPGDNlFANS-LVALDAATGKRRWHFQTVHHDLWDYDLPAQPTLV-DVPRDGK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 341 SMDMVVGSDKTGWVYMMDAESG-------------------------------------DLHERSeeicqhinMWEMIP- 382
Cdd:cd10280 310 TVPAVAQPTKQGFVFVLDRRTGkplwpveerpvpqgdvpgertsptqpfptlpppfarqGLTEDD--------MWGATPf 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 383 -------------------HISEDERVPFvPGAPGGNDWQPPSYNPETGLVYVihqnYPQDLYWRY--EEFSEGNPYWGG 441
Cdd:cd10280 382 dqlacriqfrslryeglftPPSLDGTLIF-PGNDGGANWGGAAVDPERGILYV----NSNRLPFVIqlVPRAPGDPAGVA 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 442 GLADPASEFPDEWNGAITAFA-----------------------AVDPTTGERVWREWI-ESEDDH------------YM 485
Cdd:cd10280 457 GGGEGGGGGGGPSPQAGTPYGvgrgrflsplglpcqappwgtltAIDLNTGKILWQVPLgTVPDLGpkgiplpiptgtPN 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 486 WGGSLSTATGLVF-NGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSwYDPDeGKQYVAVQVGGSGWLrQGPRGDTLAV 564
Cdd:cd10280 537 LGGPVVTAGGLVFiAATQDNYLRAFDKATGKELWEARLPAGGQATPMT-YEVD-GKQYVVIAAGGHGSL-GTKRGDSVIA 613
|
.
gi 1621087063 565 F 565
Cdd:cd10280 614 Y 614
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
77-238 |
3.18e-14 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 74.29 E-value: 3.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 77 PADVITPENVADLELEYELSVGTGSS--MEGTPIVVPGDppvMYQTNGPNHMKAIDPREGEILWSYTYAVPmGVELccdd 154
Cdd:cd10276 2 PTDLPEPTPEFDPEVLWSKSVGNGGMagIDLTPVVAGDM---VYAADANGQVSAFNATTGKIIWETSLSGK-GFLG---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 155 nnRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEegysATWAPVVHDGTIYTGSAGGEYgvlgfiAAIDAESG 234
Cdd:cd10276 74 --GTPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSDSQ----LLSPPTYADGKIYVGTGDGRL------YYCNAETG 141
|
....
gi 1621087063 235 EIQW 238
Cdd:cd10276 142 KVVW 145
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
104-241 |
1.05e-10 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 62.04 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 104 EGTPIVVPGDppvmyqtngpNHMKAIDPREGEILWSYTYAVPMGVELccddNNRGAAVHGDTVYMTTLDSGVVALDRYTG 183
Cdd:pfam13360 73 GGRVFVVAGD----------GSLIALDAADGRRLWSYQRSGEPLALR----SSGSPAVVGDTVVAGFSSGKLVALDPATG 138
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1621087063 184 EERWYTS------TADHEEGYSATWAPVVHDGTIYtgsAGGEYGVLGfiaAIDAESGEIQWQTD 241
Cdd:pfam13360 139 KVRWEAPlaaprgTNELERLVDITGTPVVAGGRVF---ASAYQGRLV---AFDAATGRRLWTRE 196
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
128-363 |
2.26e-09 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 59.44 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 128 AIDPREGEILWSYT-----YAVPmgvelccddnnrgaAVHGDTVYMTTLDSGVVALDRYTGEERWytsTADHEE------ 196
Cdd:COG1520 111 ALDADDGEELWRARlssevLAAP--------------AVAGGRVVVRTGDGRVYALDAATGERLW---SYQRPVpaltlr 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 197 GYSAtwaPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDtlledewVGASRehgcGTSW--------MTPTIDE 268
Cdd:COG1520 174 GTSS---PVIVGGAVLVGFANGK------LVALDLANGQPLWEQR-------VAQPR----GRTElerlvdvdGTPVVDG 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 269 eaGVLYtAVAnpgpdFDGTVrpgpnfptcgtISLDLESGEFQWG--FQSSphdvwdydavaprvlvRDVETDDGsmdMVV 346
Cdd:COG1520 234 --GVVY-AVA-----YQGRL-----------AALDLRSGRVLWSrdLSSY----------------TGLAVDGN---NLY 275
|
250
....*....|....*..
gi 1621087063 347 GSDKTGWVYMMDAESGD 363
Cdd:COG1520 276 VTDDDGRVWALDRRNGA 292
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
127-245 |
1.42e-08 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 55.49 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 127 KAIDPREGEILWSYTYAVPMGVelccddnnrGAAVHGDTVYMTTLDSGVVALDRYTGEERWytSTADHEEGYSatwAPVV 206
Cdd:pfam13360 6 TALDAATGAELWRVDLETGLGG---------GVAVDGGRLFVATGGGQLVALDAATGKLLW--RQTLSGEVLG---APLV 71
|
90 100 110
....*....|....*....|....*....|....*....
gi 1621087063 207 HDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDTLLE 245
Cdd:pfam13360 72 AGGRVFVVAGDGS------LIALDAADGRRLWSYQRSGE 104
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
110-321 |
1.65e-08 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 55.49 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 110 VPGDPPVMYQTNGPNHMKAIDPREGEILWSYTYAVPMgvelccddnnRGA-AVHGDTVYMTTLDSGVVALDRYTGEERWY 188
Cdd:pfam13360 29 VAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEV----------LGApLVAGGRVFVVAGDGSLIALDAADGRRLWS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 189 TSTADHEEGYSATWAPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTdTLLEDEwvGASREHGCGTSWMTPTIDE 268
Cdd:pfam13360 99 YQRSGEPLALRSSGSPAVVGDTVVAGFSSGK------LVALDPATGKVRWEA-PLAAPR--GTNELERLVDITGTPVVAG 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1621087063 269 eaGVLYtAVANPGpdfdgtvrpgpnfptcGTISLDLESGEFQWG-FQSSPHDVW 321
Cdd:pfam13360 170 --GRVF-ASAYQG----------------RLVAFDAATGRRLWTrEISGPNGPI 204
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
160-240 |
1.32e-07 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 54.05 E-value: 1.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 160 AVHGDTVYMTTLDSGVVALDRYTGEERWytsTADHEEGYSAtwAPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQ 239
Cdd:COG1520 54 AVAGDRVYAADADGRVAALDAATGKELW---RVDLGEPLSG--GVGADGGLVVVGTEDGE------VIALDADDGEELWR 122
|
.
gi 1621087063 240 T 240
Cdd:COG1520 123 A 123
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
71-364 |
1.38e-07 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 53.78 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 71 EQHRATPADVITPENVADLELEYELSVGTGSSMEGTPIVVPGDPPVMYQTNGPNHMKAIDPREGEILWSytyaVPMGVEL 150
Cdd:TIGR03300 22 EDDEPQPAELPEFQPTVKVDQVWSASVGDGVGHYYLRLQPAVAGGKVYAADADGTVAALDAETGKRLWR----VDLDERL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 151 ccddnNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWYT-------------------STAD-HEEGYSAT-----W--- 202
Cdd:TIGR03300 98 -----SGGVGADGGLVFVGTEKGEVIALDAEDGKELWRAklssevlspplvanglvvvRTNDgRLTALDAAtgerlWtys 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 203 ------------APVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDtlledewVGASRehgcGTSW--------M 262
Cdd:TIGR03300 173 rvtppltlrgsaSPVIADGGVLVGFAGGK------LVALDLQTGQPLWEQR-------VALPK----GRTElerlvdvdG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 263 TPTIDEeaGVLYtAVAnpgpdFDGTVrpgpnfptcgtISLDLESGEFQWGFQ-SSPHDVwdydAVAPRVL--------VR 333
Cdd:TIGR03300 236 DPVVDG--GQVY-AVS-----YQGRV-----------AALDLRSGRVLWKRDaSSYQGP----AVDDNRLyvtdadgvVV 292
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1621087063 334 DVETDDGSM--------------------DMVVGsDKTGWVYMMDAESGDL 364
Cdd:TIGR03300 293 ALDRRSGSElwkndelkyrqltapavlggYLVVG-DFEGYLHWLDRDDGSF 342
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
104-187 |
5.62e-07 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 50.86 E-value: 5.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 104 EGTPIVVPGdppVMYQTNGPNHMKAIDPREGEILWSYTYAVPMGVelccddnnrgaAVHGDTVYMTTLDSGVVALDRYTG 183
Cdd:pfam13360 162 TGTPVVAGG---RVFASAYQGRLVAFDAATGRRLWTREISGPNGP-----------ILDGDLLYVVSDDGELYALDRATG 227
|
....
gi 1621087063 184 EERW 187
Cdd:pfam13360 228 AVVW 231
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
160-241 |
6.08e-07 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 51.56 E-value: 6.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 160 AVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADhEEGYSATwaPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQ 239
Cdd:cd10276 35 VVAGDMVYAADANGQVSAFNATTGKIIWETSLSG-KGFLGGT--PAVGNGKIFVGTESGY------LYALDAKDGSELWR 105
|
..
gi 1621087063 240 TD 241
Cdd:cd10276 106 TE 107
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
127-239 |
8.75e-07 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 51.47 E-value: 8.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 127 KAIDPREGEILWSYTYAVPMGvelcCDDNNRGA------AVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADheEGYSa 200
Cdd:PRK11138 82 KALDADTGKEIWSVDLSEKDG----WFSKNKSAllsggvTVAGGKVYIGSEKGQVYALNAEDGEVAWQTKVAG--EALS- 154
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1621087063 201 twAPVVHDGT--IYTGSaggeygvlGFIAAIDAESGEIQWQ 239
Cdd:PRK11138 155 --RPVVSDGLvlVHTSN--------GMLQALNESDGAVKWT 185
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
462-530 |
1.49e-06 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 49.71 E-value: 1.49e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1621087063 462 AAVDPTTGERVWREwieseDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASP 530
Cdd:pfam13360 6 TALDAATGAELWRV-----DLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAP 69
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
172-520 |
2.08e-06 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 48.94 E-value: 2.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 172 DSGVVALDRYTGEERWytsTADHEEGYSatWAPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDtlLEDEWVGA 251
Cdd:pfam13360 2 DGVVTALDAATGAELW---RVDLETGLG--GGVAVDGGRLFVATGGGQ------LVALDAATGKLLWRQT--LSGEVLGA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 252 srehgcgtswmtPTIDEEAGVLYTAvanpgpdfDGTVrpgpnfptcgtISLDLESGEFQWGFQSSPHdvwdydavAPRVL 331
Cdd:pfam13360 69 ------------PLVAGGRVFVVAG--------DGSL-----------IALDAADGRRLWSYQRSGE--------PLALR 109
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 332 VRDVETDDGSMDMVVGSDktGWVYMMDAESGDLherseeicqhinMWE----MIPHISEDERVPFVPGAPGGNDwqppsy 407
Cdd:pfam13360 110 SSGSPAVVGDTVVAGFSS--GKLVALDPATGKV------------RWEaplaAPRGTNELERLVDITGTPVVAG------ 169
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 408 npetGLVYVIHQNYpqdlywryeefsegnpywgggladpasefpdewngaitAFAAVDPTTGERVWrEWIESeddhymWG 487
Cdd:pfam13360 170 ----GRVFASAYQG--------------------------------------RLVAFDAATGRRLW-TREIS------GP 200
|
330 340 350
....*....|....*....|....*....|...
gi 1621087063 488 GSLSTATGLVFNGTQNGTFVAYDGETGDRLWEY 520
Cdd:pfam13360 201 NGPILDGDLLYVVSDDGELYALDRATGAVVWKT 233
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
128-244 |
1.20e-05 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 47.89 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 128 AIDPREGEILWSYTYAVPMGV-ELccddnNR------GAAVHGDTVYMTTLDSGVVALDRYTGEERWytstadhEEGYSA 200
Cdd:COG1520 196 ALDLANGQPLWEQRVAQPRGRtEL-----ERlvdvdgTPVVDGGVVYAVAYQGRLAALDLRSGRVLW-------SRDLSS 263
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1621087063 201 TWAPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDTLL 244
Cdd:COG1520 264 YTGLAVDGNNLYVTDDDGR------VWALDRRNGAELWKQDALL 301
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
106-236 |
3.50e-05 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 46.46 E-value: 3.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 106 TPIVVPGdppVMYQT--NGpnHMKAIDPREGEILWSYTYAvpmgvelccddNNRGAAVHGDTVYMTTLDSGVVALDRYTG 183
Cdd:PRK11138 251 TPVVVGG---VVYALayNG--NLVALDLRSGQIVWKREYG-----------SVNDFAVDGGRIYLVDQNDRVYALDTRGG 314
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1621087063 184 EERWYTSTADHEegySATwAPVVHDGTIYTGSAggeygvLGFIAAIDAESGEI 236
Cdd:PRK11138 315 VELWSQSDLLHR---LLT-APVLYNGYLVVGDS------EGYLHWINREDGRF 357
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
128-242 |
4.52e-05 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 45.96 E-value: 4.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 128 AIDPREGEILWSYTYAVpmgvelccddnNRGAAVHGDTVYMTTLDSGVVALDRYTGEERWytsTADHEEGYSATwAPVVH 207
Cdd:COG1520 247 ALDLRSGRVLWSRDLSS-----------YTGLAVDGNNLYVTDDDGRVWALDRRNGAELW---KQDALLYRGLT-APVVL 311
|
90 100 110
....*....|....*....|....*....|....*
gi 1621087063 208 DGTIYTGSAGgeygvlGFIAAIDAESGEIQWQTDT 242
Cdd:COG1520 312 GDYVVVGDFE------GYLHWLSRDDGSLVARLRV 340
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
462-525 |
7.68e-05 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 45.31 E-value: 7.68e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1621087063 462 AAVDPTTGERVWREWIESEddhymwggSLSTAT---GLVFNGTQNGTFVAYDGETGDRLWEYEFDVP 525
Cdd:PRK11138 133 YALNAEDGEVAWQTKVAGE--------ALSRPVvsdGLVLVHTSNGMLQALNESDGAVKWTVNLDVP 191
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
184-242 |
8.58e-05 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 45.19 E-value: 8.58e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1621087063 184 EERWYTSTADHEEGYSATWAPVVHDGTIYTGSAGGEygvlgfIAAIDAESGEIQWQTDT 242
Cdd:COG1520 33 KQLWSASVGDGVGKGYSRLAPAVAGDRVYAADADGR------VAALDAATGKELWRVDL 85
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
463-525 |
1.94e-04 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 43.77 E-value: 1.94e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1621087063 463 AVDPTTGERVWREWIESEddhymwggSLS---TATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVP 525
Cdd:TIGR03300 119 ALDAEDGKELWRAKLSSE--------VLSpplVANGLVVVRTNDGRLTALDAATGERLWTYSRVTP 176
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
160-240 |
2.48e-04 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 43.77 E-value: 2.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 160 AVHGDTVYMTTLDSGVVALDRYTGEERWYTSTADHEEGYSATW------APVVHDGTIYTGSAGGEygvlgfIAAIDAES 233
Cdd:PRK11138 66 AVAYNKVYAADRAGLVKALDADTGKEIWSVDLSEKDGWFSKNKsallsgGVTVAGGKVYIGSEKGQ------VYALNAED 139
|
....*..
gi 1621087063 234 GEIQWQT 240
Cdd:PRK11138 140 GEVAWQT 146
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
462-519 |
3.76e-04 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 43.00 E-value: 3.76e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1621087063 462 AAVDPTTGERVW------REWIESEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWE 519
Cdd:PRK11138 82 KALDADTGKEIWsvdlseKDGWFSKNKSALLSGGVTVAGGKVYIGSEKGQVYALNAEDGEVAWQ 145
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
462-569 |
4.70e-04 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 42.61 E-value: 4.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 462 AAVDPT-TGERVWREWIESEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSwydpDEGK 540
Cdd:TIGR03300 32 PEFQPTvKVDQVWSASVGDGVGHYYLRLQPAVAGGKVYAADADGTVAALDAETGKRLWRVDLDERLSGGVGA----DGGL 107
|
90 100
....*....|....*....|....*....
gi 1621087063 541 QYVAvqvggsgwlrqGPRGDTLAvFSMED 569
Cdd:TIGR03300 108 VFVG-----------TEKGEVIA-LDAED 124
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
470-544 |
9.44e-04 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 41.72 E-value: 9.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1621087063 470 ERVWREWIESEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSwydpDEGKQYVA 544
Cdd:COG1520 33 KQLWSASVGDGVGKGYSRLAPAVAGDRVYAADADGRVAALDAATGKELWRVDLGEPLSGGVGA----DGGLVVVG 103
|
|
| Luminal_IRE1 |
cd09769 |
The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, ... |
164-212 |
1.03e-03 |
|
The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1; The Luminal domain is a dimerization domain present in Inositol-requiring protein 1 (IRE1), a serine/threonine protein kinase (STK) and a type I transmembrane protein that is localized in the endoplasmic reticulum (ER). IRE1, also called Endoplasmic reticulum (ER)-to-nucleus signaling protein (or ERN), is a kinase receptor that also contains an endoribonuclease domain in the cytoplasmic side. It plays roles in the signaling of the unfolded protein response (UPR), which is activated when protein misfolding is detected in the ER in order to decrease the synthesis of new proteins and increase the capacity of the ER to cope with the stress. IRE1 acts as an ER stress sensor and is the oldest and most conserved component of the UPR in eukaryotes. During ER stress, IRE1 dimerizes through its luminal domain and forms oligomers, allowing the kinase domain to undergo trans-autophosphorylation. This leads to a conformational change that stimulates its endoribonuclease activity and results in the cleavage of its mRNA substrate, HAC1 in yeast and Xbp1 in metazoans, promoting a splicing event that enables translation into a transcription factor which activates the UPR. Mammals contain two IRE1 proteins, IRE1alpha (or ERN1) and IRE1beta (or ERN2). IRE1alpha is expressed in all cells and tissues while IRE1beta is found only in intestinal epithelial cells.
Pssm-ID: 188875 [Multi-domain] Cd Length: 295 Bit Score: 41.15 E-value: 1.03e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1621087063 164 DTVYMTTLDSGVVALDRYTGEERW--------YTSTADHEEGYS-ATWAPVVHDGTIY 212
Cdd:cd09769 2 DLLLVSTVDGGLHAVDRKTGKILWslkaedplVEVPHHSTLSIDgPTFIVEPRDGSLY 59
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
455-519 |
1.88e-03 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 40.78 E-value: 1.88e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1621087063 455 NGAITAFAAvdpTTGERVWREwieSEDDHYMWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWE 519
Cdd:cd10276 47 NGQVSAFNA---TTGKIIWET---SLSGKGFLGGTPAVGNGKIFVGTESGYLYALDAKDGSELWR 105
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
462-525 |
1.97e-03 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 40.57 E-value: 1.97e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1621087063 462 AAVDPTTGERVWREWIESEddhymwggSLST---ATGLVFNGTQNGTFVAYDGETGDRLWEYEFDVP 525
Cdd:COG1520 110 IALDADDGEELWRARLSSE--------VLAApavAGGRVVVRTGDGRVYALDAATGERLWSYQRPVP 168
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
461-521 |
2.99e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 39.69 E-value: 2.99e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1621087063 461 FAAVDPTTGERVWREWIESEddhymWGGSLSTATGLVFNGTQNGTFVAYDGETGDRLWEYE 521
Cdd:pfam13360 45 LVALDAATGKLLWRQTLSGE-----VLGAPLVAGGRVFVVAGDGSLIALDAADGRRLWSYQ 100
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
164-194 |
3.45e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.25 E-value: 3.45e-03
10 20 30
....*....|....*....|....*....|.
gi 1621087063 164 DTVYMTTLDSGVVALDRYTGEERWYTSTADH 194
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGA 31
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
495-530 |
4.12e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.25 E-value: 4.12e-03
10 20 30
....*....|....*....|....*....|....*.
gi 1621087063 495 GLVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASP 530
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
424-534 |
6.61e-03 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 38.85 E-value: 6.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 424 DLYWRYE----EFSEGNPYWGGGLADPASEfpdewNGAITAFaavDPTTGERVWREWIESeddhymwgGSLST----ATG 495
Cdd:cd10276 59 KIIWETSlsgkGFLGGTPAVGNGKIFVGTE-----SGYLYAL---DAKDGSELWRTEVSD--------SQLLSpptyADG 122
|
90 100 110
....*....|....*....|....*....|....*....
gi 1621087063 496 LVFNGTQNGTFVAYDGETGDRLWEYEFDVPISASPMSWY 534
Cdd:cd10276 123 KIYVGTGDGRLYYCNAETGKVVWNRTSTAPELSLRGGAA 161
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
440-518 |
8.97e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 38.76 E-value: 8.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1621087063 440 GGGLADPASEF-PDEWNGAITA------FAAVDPTTGERVWREWIESEddhymWGGSLSTATGLVFNGTQNGTFVAYDGE 512
Cdd:TIGR03300 49 GDGVGHYYLRLqPAVAGGKVYAadadgtVAALDAETGKRLWRVDLDER-----LSGGVGADGGLVFVGTEKGEVIALDAE 123
|
....*.
gi 1621087063 513 TGDRLW 518
Cdd:TIGR03300 124 DGKELW 129
|
|
| |
