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Conserved domains on  [gi|1619092274|gb|THC91108|]
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hypothetical protein EYZ11_009422 [Aspergillus tanneri]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 15620386)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 314-362 2.30e-09

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


:

Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 53.34  E-value: 2.30e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1619092274 314 PPALTQFCSVYASaadgssHNIYIYGGYDGlkTDSAPSDDVYVLSVPSF 362
Cdd:pfam13854   1 PVPRYGHCAVTVG------DYIYLYGGYTG--GEGQPSDDVYVLSLPTF 41
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
289-458 3.19e-07

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 52.47  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 289 SFMQTVSVYDVAQDRWYlqnTTGDMP-PALTQFCSVyasAADGsshNIYIYGGYDGLKTDSAPSDDVYVLSVPSFEWIKL 367
Cdd:COG3055    35 SASNSFEVYDPATNTWS---ELAPLPgPPRHHAAAV---AQDG---KLYVFGGFTGANPSSTPLNDVYVYDPATNTWTKL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 368 YSGEKrhGRRGHRCVkPYPDKMLVLGGVyrtaSDCLDGGIVQVFNLNTGQfqdeydpekWSdyKVPDLVSGRIGGGAQ-- 445
Cdd:COG3055   106 APMPT--PRGGATAL-LLDGKIYVVGGW----DDGGNVAWVEVYDPATGT---------WT--QLAPLPTPRDHLAAAvl 167

                         170       180
                  ....*....|....*....|..
gi 1619092274 446 ---------GDADQRAPKSWTN 458
Cdd:COG3055   168 pdgkilvigGRNGSGFSNTWTT 189
 
Name Accession Description Interval E-value
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 314-362 2.30e-09

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 53.34  E-value: 2.30e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1619092274 314 PPALTQFCSVYASaadgssHNIYIYGGYDGlkTDSAPSDDVYVLSVPSF 362
Cdd:pfam13854   1 PVPRYGHCAVTVG------DYIYLYGGYTG--GEGQPSDDVYVLSLPTF 41
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
289-458 3.19e-07

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 52.47  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 289 SFMQTVSVYDVAQDRWYlqnTTGDMP-PALTQFCSVyasAADGsshNIYIYGGYDGLKTDSAPSDDVYVLSVPSFEWIKL 367
Cdd:COG3055    35 SASNSFEVYDPATNTWS---ELAPLPgPPRHHAAAV---AQDG---KLYVFGGFTGANPSSTPLNDVYVYDPATNTWTKL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 368 YSGEKrhGRRGHRCVkPYPDKMLVLGGVyrtaSDCLDGGIVQVFNLNTGQfqdeydpekWSdyKVPDLVSGRIGGGAQ-- 445
Cdd:COG3055   106 APMPT--PRGGATAL-LLDGKIYVVGGW----DDGGNVAWVEVYDPATGT---------WT--QLAPLPTPRDHLAAAvl 167

                         170       180
                  ....*....|....*....|..
gi 1619092274 446 ---------GDADQRAPKSWTN 458
Cdd:COG3055   168 pdgkilvigGRNGSGFSNTWTT 189
 
Name Accession Description Interval E-value
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 314-362 2.30e-09

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 53.34  E-value: 2.30e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1619092274 314 PPALTQFCSVYASaadgssHNIYIYGGYDGlkTDSAPSDDVYVLSVPSF 362
Cdd:pfam13854   1 PVPRYGHCAVTVG------DYIYLYGGYTG--GEGQPSDDVYVLSLPTF 41
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
289-458 3.19e-07

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 52.47  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 289 SFMQTVSVYDVAQDRWYlqnTTGDMP-PALTQFCSVyasAADGsshNIYIYGGYDGLKTDSAPSDDVYVLSVPSFEWIKL 367
Cdd:COG3055    35 SASNSFEVYDPATNTWS---ELAPLPgPPRHHAAAV---AQDG---KLYVFGGFTGANPSSTPLNDVYVYDPATNTWTKL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1619092274 368 YSGEKrhGRRGHRCVkPYPDKMLVLGGVyrtaSDCLDGGIVQVFNLNTGQfqdeydpekWSdyKVPDLVSGRIGGGAQ-- 445
Cdd:COG3055   106 APMPT--PRGGATAL-LLDGKIYVVGGW----DDGGNVAWVEVYDPATGT---------WT--QLAPLPTPRDHLAAAvl 167

                         170       180
                  ....*....|....*....|..
gi 1619092274 446 ---------GDADQRAPKSWTN 458
Cdd:COG3055   168 pdgkilvigGRNGSGFSNTWTT 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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