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Conserved domains on  [gi|1601836392|gb|QBQ41182|]
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XRE family transcriptional regulator [Sphingobacterium psychroaquaticum]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
11-88 1.43e-06

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 42.29  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601836392 11 NSLEVQVGKRFKEFRLTYNIKQTDI-EI--MQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEKLSTRKIADPK 87
Cdd:COG1396    2 STLKKALGERLRELRKARGLTQEELaERlgVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81


                 .
gi 1601836392 88 K 88
Cdd:COG1396   82 E 82
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
11-88 1.43e-06

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 42.29  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601836392 11 NSLEVQVGKRFKEFRLTYNIKQTDI-EI--MQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEKLSTRKIADPK 87
Cdd:COG1396    2 STLKKALGERLRELRKARGLTQEELaERlgVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81


                 .
gi 1601836392 88 K 88
Cdd:COG1396   82 E 82
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 18-72 6.96e-06

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 39.84  E-value: 6.96e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 1601836392 18 GKRFKEFRLTYNIKQTDIE---IMQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWL 72
Cdd:cd00093    1 GERLKELRKEKGLTQEELAeklGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 18-78 2.15e-03

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 33.42  E-value: 2.15e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1601836392 18 GKRFKEFRLTYNIKQTDIE---IMQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEKL 78
Cdd:pfam12844  1 GERLRKAREERGLTQEELAerlGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLLQGEGE 64
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
20-72 3.47e-03

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 32.88  E-value: 3.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1601836392  20 RFKEFRLTYNIKQTDI-EIMQ--KQNVSRIENGNRLPSHELMIYMLTKYNMDLNWL 72
Cdd:smart00530  1 RLKELREEKGLTQEELaEKLGvsRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
11-88 1.43e-06

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 42.29  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1601836392 11 NSLEVQVGKRFKEFRLTYNIKQTDI-EI--MQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEKLSTRKIADPK 87
Cdd:COG1396    2 STLKKALGERLRELRKARGLTQEELaERlgVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81


                 .
gi 1601836392 88 K 88
Cdd:COG1396   82 E 82
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 18-72 6.96e-06

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 39.84  E-value: 6.96e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 1601836392 18 GKRFKEFRLTYNIKQTDIE---IMQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWL 72
Cdd:cd00093    1 GERLKELRKEKGLTQEELAeklGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
16-77 1.56e-05

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 39.06  E-value: 1.56e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1601836392 16 QVGKRFKEFRLTYNIKQTD----IEImQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEK 77
Cdd:COG1476    4 KLGNRLKELRKERGLTQEElaelLGV-SRQTISAIENGKYNPSLELALKIARALGVSLEELFSLEE 68
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 18-78 2.15e-03

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 33.42  E-value: 2.15e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1601836392 18 GKRFKEFRLTYNIKQTDIE---IMQKQNVSRIENGNRLPSHELMIYMLTKYNMDLNWLLTGEKL 78
Cdd:pfam12844  1 GERLRKAREERGLTQEELAerlGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLLQGEGE 64
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
20-72 3.47e-03

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 32.88  E-value: 3.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1601836392  20 RFKEFRLTYNIKQTDI-EIMQ--KQNVSRIENGNRLPSHELMIYMLTKYNMDLNWL 72
Cdd:smart00530  1 RLKELREEKGLTQEELaEKLGvsRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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