|
Name |
Accession |
Description |
Interval |
E-value |
| DEAH_box_HrpA |
TIGR01967 |
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ... |
94-1398 |
0e+00 |
|
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria and a few high-GC Gram-positive bacteria. HrpA is about 1300 amino acids long, while its paralog HrpB, also uncharacterized, is about 800 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. The HrpA/B homolog from Borrelia is 500 amino acids shorter but appears to be derived from HrpA rather than HrpB. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273900 [Multi-domain] Cd Length: 1283 Bit Score: 1396.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 94 VPPITYPESLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTgligHTQPRRLAASSTGRRIA 173
Cdd:TIGR01967 57 VPEIRYPDNLPVSAKREDIAEAIAENQVVIIAGETGSGKTTQLPKICLELGRGSHGLIG----HTQPRRLAARTVAQRIA 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 174 EELGTPFGEVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDL 253
Cdd:TIGR01967 133 EELGTPLGEKVGYKVRFHDQVSSNTLVKLMTDGILLAETQQDRFLSRYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 254 KLIVTSATIDADRFARHFGTderpAPVIEVSGRLYPVEMRYRPVAEDrpavknaegtggrdrvktAREAERDLMDAIVDA 333
Cdd:TIGR01967 213 KIIITSATIDPERFSRHFNN----APIIEVSGRTYPVEVRYRPLVEE------------------QEDDDLDQLEAILDA 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 334 VDELCREGPGDVLVFLPGEREIREAAEALRKHHPPHTEILPLFARLSAADQDKVFKASNARRIVLATNVAETSLTVPGIR 413
Cdd:TIGR01967 271 VDELFAEGPGDILIFLPGEREIRDAAEILRKRNLRHTEILPLYARLSNKEQQRVFQPHSGRRIVLATNVAETSLTVPGIH 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 414 YVVDTGLARVKRYSYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYEESDYQARARFTDPEILRSSLASVILRMK 493
Cdd:TIGR01967 351 YVIDTGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVAPGICIRLYSEEDFNSRPEFTDPEILRTNLASVILQML 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 494 SLHLTAIESFPFLEPPPGRAIADGYQLLNELGAVDDDNA---LTPLGRELARLPLDPRVGRMILAARDQQSLREVLIIAS 570
Cdd:TIGR01967 431 ALRLGDIAAFPFIEAPDPRAIRDGFRLLEELGALDDDEAepqLTPIGRQLAQLPVDPRLARMLLEAHRLGCLQEVLIIAS 510
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 571 ALSVQDPRDRPIEAQEQADQAHRRFADERSEFLQWLKIWAWFEEAVAHKKSNrQLVDACRQNFLSHLRLREWRDVHSQLL 650
Cdd:TIGR01967 511 ALSIQDPRERPMEKQQAADQAHARFKDPRSDFLSRVNLWRHIEEQRQALSAN-QFRNACRKQYLNYLRVREWQDIYRQLT 589
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 651 TVVREHGWRLNEAEATYEQVHLALLTGLLGNLGLKaDDDPHYLGARGIKFYLWPGSVLAKKAGRWVMAAELVETSRLYAR 730
Cdd:TIGR01967 590 QVVKELGLKLNEEPADYDAIHKALLSGLLSQIGMK-DEKHEYDGARGRKFHIFPGSPLFKKPPKWVMAAELVETSKLYAR 668
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 731 CLAKIEPEWVEKIGAHLLKKSLSEPHWEKRPAQVSAFERATLYGLPIYHRRRVAFGKQDPARARELFIRGALVEGEFDTK 810
Cdd:TIGR01967 669 LVAKIEPEWVEPVAGHLIKKNYFEPHWEKKRGQVMAYEKVTLYGLTLVARRSVPYGPIDPADAREMFIRHALVEGEWQTR 748
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 811 LPFFAHNRKLLADIEQLEHKSRRQDVLVDDELIYAYYDQAIPAGIHTGAAFERWYRDEVKKggQPEdkqrLLYLSRDDLM 890
Cdd:TIGR01967 749 AAFFQANRALLEEVEELEHKARRRDILVDEQTLFDFYDGRLPEDINNARHFDSWWKKASRK--QPD----LLDFPKEVLF 822
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 891 RHEAAGVTTELFPKRATMAGVEMALTYHFEPGTPRDGVTLAVPLYALNQVDARRCEWLVPGMLKEKVQLLLKSLPQKLRR 970
Cdd:TIGR01967 823 QRRANVISAAQFPDHWHKGDLRLALSYHFEPGHGDDGVTVHIPLPLLNQLDTEDFDWLVPGLREEKVVALIKSLPKALRR 902
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 971 HCVPLPEYAAGFVERMgreRFGAGGLVEALIADVRGETQVAMKTADFKLETLPAHLFMNFKVIDEHGRQLAMGRNLAQLR 1050
Cdd:TIGR01967 903 NFVPAPDFAKACLARL---PPNQGPLTDALARELRRMTGERVNPEDWDWEQLPDHLQMNFRIVDDKGKVLAQGRDLALLK 979
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1051 QELGAQAQQQFqkiaaastiaaggdadagqpvgqapaaagpagapgrgpkpakgaapqtSAPAEAGATAlyENLTTWNFG 1130
Cdd:TIGR01967 980 ERLAGDVRAAL------------------------------------------------SAVADVGIEK--SGLTNWSFG 1009
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1131 KLPELLEIRRRGQTLYGYPALVDRGTHCDVEVFDSPEEAARIHRAGLRRLFALQLKEPIKFLEKNLPGLREMAMQYMSLG 1210
Cdd:TIGR01967 1010 PLPERMEQKTGNYKVTAYPALVDDGGSVAIKLFDTQAEAEAAHRAGLRRLLLLQIPSPVKMLQGKLPNKAKLALYYNPLG 1089
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1211 TQDELRDQLIDTALDRACLQDP-LPDDDASFHARRDEGRSRLNLLAQEIARLVGQVLAEYAGLVKKLAQAKPFAQAHA-- 1287
Cdd:TIGR01967 1090 RVEVLVDDILHAAVDRLIFENGgQVRTQADFAALLAQVRAELAPEVERIAKQLEEILVLFGNIRKRLKGKIDPTQAKAls 1169
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1288 DLQQQLAALVGKRFVIDTPYAQLAHFPRYLKGIALRIDKLKADPARDAKQSADLLPLAQQYQRAVS--QRGGVADPRLAE 1365
Cdd:TIGR01967 1170 DIKAQLDKLVYQGFVRTTGPQRLSHLPRYLKAMELRLEKLRVDPGRDRERQAEISNVQEAYDARLAklPHERRLPAALVE 1249
|
1290 1300 1310
....*....|....*....|....*....|...
gi 1600237547 1366 FRWLLEELRISLFAQELRTPMPVSVKRLHKVWE 1398
Cdd:TIGR01967 1250 IRWMIEEYRVSLFAQQLGTAYPISDKRILKYYR 1282
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
94-1393 |
0e+00 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 1380.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 94 VPPITYPESLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTgligHTQPRRLAASSTGRRIA 173
Cdd:PRK11131 64 RPEITYPENLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLELGRGVKGLIG----HTQPRRLAARTVANRIA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 174 EELGTPFGEVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDL 253
Cdd:PRK11131 140 EELETELGGCVGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDL 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 254 KLIVTSATIDADRFARHFGTderpAPVIEVSGRLYPVEMRYRPVAEDrpavknaegtggrdrvktAREAERDLMDAIVDA 333
Cdd:PRK11131 220 KVIITSATIDPERFSRHFNN----APIIEVSGRTYPVEVRYRPIVEE------------------ADDTERDQLQAIFDA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 334 VDELCREGPGDVLVFLPGEREIREAAEALRKHHPPHTEILPLFARLSAADQDKVFKASNARRIVLATNVAETSLTVPGIR 413
Cdd:PRK11131 278 VDELGREGPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIK 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 414 YVVDTGLARVKRYSYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYEESDYQARARFTDPEILRSSLASVILRMK 493
Cdd:PRK11131 358 YVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMT 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 494 SLHLTAIESFPFLEPPPGRAIADGYQLLNELGAVDDDNA-----LTPLGRELARLPLDPRVGRMILAARDQQSLREVLII 568
Cdd:PRK11131 438 ALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMII 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 569 ASALSVQDPRDRPIEAQEQADQAHRRFADERSEFLQWLKIWAWFEEAVAHKKSNrQLVDACRQNFLSHLRLREWRDVHSQ 648
Cdd:PRK11131 518 TSALSIQDPRERPMDKQQASDEKHRRFADKESDFLAFVNLWNYLQEQQKALSSN-QFRRLCRTDYLNYLRVREWQDIYTQ 596
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 649 LLTVVREHGWRLNEAEATYEQVHLALLTGLLGNLGLKADDDPHYLGARGIKFYLWPGSVLAKKAGRWVMAAELVETSRLY 728
Cdd:PRK11131 597 LRQVVKELGIPVNSEPAEYREIHTALLTGLLSHIGMKDAEKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLW 676
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 729 ARCLAKIEPEWVEKIGAHLLKKSLSEPHWEKRPAQVSAFERATLYGLPIYHRRRVAFGKQDPARARELFIRGALVEGEFD 808
Cdd:PRK11131 677 GRIAARIEPEWIEPLAQHLIKRSYSEPHWEKAQGAVMATEKVTLYGLPIVAARKVNYGQIDPALCRELFIRHALVEGDWQ 756
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 809 TKLPFFAHNRKLLADIEQLEHKSRRQDVLVDDELIYAYYDQAIPAGIHTGAAFERWYRDEVKKggQPEdkqrLLYLSRDD 888
Cdd:PRK11131 757 TRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIGHDVVSARHFDSWWKKASRE--TPE----LLNFEKSM 830
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 889 LMRHEAAGVTTELFPKRATMAGVEMALTYHFEPGTPRDGVTLAVPLYALNQVDARRCEWLVPGMLKEKVQLLLKSLPQKL 968
Cdd:PRK11131 831 LIKEGAEKVSKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFDWQIPGLRRELVIALIKSLPKPV 910
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 969 RRHCVPLPEYAAGFVERMGRERfgaGGLVEALIADVRGETQVAMKTADFKLETLPAHLFMNFKVIDEHGRQLAMGRNLAQ 1048
Cdd:PRK11131 911 RRNFVPAPNYAEAFLGRVTPLE---LPLLDSLERELRRMTGVTVDREDWQWDQVPDHLKITFRVVDDKNKKLAEGKDLQE 987
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1049 LRQELGAQAQQqfqkiaaasTIAAGGDADAGQpvgqapaaagpagapgrgpkpakgaapqtsapaeagatalyENLTTWN 1128
Cdd:PRK11131 988 LKDALKGKVQE---------TLSAVADDGIEQ-----------------------------------------SGLHIWS 1017
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1129 FGKLPELLEIRRRGQTLYGYPALVDRGTHCDVEVFDSPEEAARIHRAGLRRLFALQLKEPIKFLEKNLPGLREMAMQYMS 1208
Cdd:PRK11131 1018 FGELPESYEQKRGGYKVKAYPALVDEKDSVAIKLFDTELEQQQAMWQGLRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNP 1097
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1209 LGTQDELRDQLIdtaldrACLQDPLPDD-------DASFHARRDEGRSRLNLLAQEIARLVGQVLAEYAGLVKKLAQAKP 1281
Cdd:PRK11131 1098 YGKVLDLIDDCI------ACGVDKLIDEnggpvwtEEGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVD 1171
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1282 F--AQAHADLQQQLAALVGKRFVIDTPYAQLAHFPRYLKGIALRIDKLKADPARDAKQSADLLPLAQQYQRAVSQ--RGG 1357
Cdd:PRK11131 1172 MtmALALSDIKAQMGGLVYRGFVTGNGWKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVESVQQAWQQWLNKlpPAR 1251
|
1290 1300 1310
....*....|....*....|....*....|....*.
gi 1600237547 1358 VADPRLAEFRWLLEELRISLFAQELRTPMPVSVKRL 1393
Cdd:PRK11131 1252 REDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRI 1287
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
95-980 |
0e+00 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 977.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 95 PPITYPESLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTgligHTQPRRLAASSTGRRIAE 174
Cdd:COG1643 2 SLITYPPDLPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLELGWGAGGRIG----MLEPRRLAARAAAERMAE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 175 ELGTPFGEVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPR-RPDL 253
Cdd:COG1643 78 ELGEPVGETVGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQPAlRPDL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 254 KLIVTSATIDADRFARHFGtderPAPVIEVSGRLYPVEMRYRPVAEDrpavknaegtggrdrvktareaERDLMDAIVDA 333
Cdd:COG1643 158 KLLVMSATLDAERFARLLG----DAPVIESSGRTYPVEVRYRPLPAD----------------------ERDLEDAVADA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 334 VDELCREGPGDVLVFLPGEREIREAAEALRKHHPPHTEILPLFARLSAADQDKVFK--ASNARRIVLATNVAETSLTVPG 411
Cdd:COG1643 212 VREALAEEPGDILVFLPGEREIRRTAEALRGRLPPDTEILPLYGRLSAAEQDRAFApaPHGRRRIVLATNIAETSLTVPG 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 412 IRYVVDTGLARVKRYSYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYEESDYQARARFTDPEILRSSLASVILR 491
Cdd:COG1643 292 IRYVIDSGLARIPRYDPRSGVTRLPTERISQASANQRAGRAGRLAPGICYRLWSEEDFARRPAFTDPEILRADLASLILE 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 492 MKSLHLTAIESFPFLEPPPGRAIADGYQLLNELGAVDDDNALTPLGRELARLPLDPRVGRMILAARDQQSLREVLIIASA 571
Cdd:COG1643 372 LAAWGLGDPEDLPFLDPPPARAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAAL 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 572 LSVQDPRdrpieaqeqadqahRRFADerSEFLQWLKIWAWFEEAvahkksnrqlvdacRQNFLSHLRLREWRDVHSQLLT 651
Cdd:COG1643 452 LSERDPR--------------RGAAG--SDLLARLNLWRRLREQ--------------QREFLSYLRLREWRDLARQLRR 501
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 652 VVREHGwrlNEAEATYEQVHLALLTGLLGNLGLKADDDPHYLGARGIKFYLWPGSVLAKKagRWVMAAELVET---SRly 728
Cdd:COG1643 502 LLGEGA---NEEPADYEAIGLLLALAYPDRIARRRGEGGRYLLARGRGAALFPGSPLAKK--EWLVAAELVGGaaeAR-- 574
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 729 ARCLAKIEPEWVEKIGAHLLKKSlSEPHWEKRPAQVSAFERATLYGLPIYHRRRvafGKQDPARARELFIRgALVEgEFD 808
Cdd:COG1643 575 IRLAAPIDPEWLEELAAHLIKRY-SEPHWDKKRGRVVARERVRLGALVLVSRPL---PGPDPEAAREALLR-ALRR-EGL 648
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 809 TKLPFFAHNRKLLADIEQLEHKS--RRQDvlVDDE-LIyayydqaipagihtgAAFERWYrdevkkggQPE--DKQRLLY 883
Cdd:COG1643 649 DLLPWSKAARQLRARVEFLERKLgeRWPD--VSDEaLL---------------ATLEDWL--------APYltGVRSLKD 703
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 884 LSRDDLMRH-------EAAGVTTELFPKR-ATMAGVEMALTYHFEPG--------------TPR--DGvTLAVPLYALNQ 939
Cdd:COG1643 704 LKRLDLLAAlrallpwEQQQRLDELAPTHlTVPSGSRLPLDYSADGPpvavrlqelfglaeTPGvaDG-RVPVPLHLLSP 782
|
890 900 910 920
....*....|....*....|....*....|....*....|..
gi 1600237547 940 V-DARRCEWLVPGMLKEKVQLLLKSLPQKLRRHCVplPEYAA 980
Cdd:COG1643 783 AgRPLQVTWDLPGFWRGSYAEVRKELRGRYPKHPW--PDDPA 822
|
|
| DUF3418 |
pfam11898 |
Domain of unknown function (DUF3418); This presumed domain is functionally uncharacterized. ... |
760-1397 |
0e+00 |
|
Domain of unknown function (DUF3418); This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is typically between 582 to 594 amino acids in length. This domain is found associated with pfam07717, pfam00271, pfam04408.
Pssm-ID: 463389 Cd Length: 587 Bit Score: 793.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 760 RPAQVSAFERATLYGLPIYHRRRVAFGKQDPARARELFIRGALVEGEFDTKLPFFAHNRKLLADIEQLEHKSRRQDVLVD 839
Cdd:pfam11898 1 KRGAVMAYERVTLYGLPIVARRRVNYGRIDPEEAREIFIRHALVEGEWRTRHTFFAHNRKLLEEVEELEHKARRRDILVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 840 DELIYAYYDQAIPAGIHTGAAFERWYRDEVKKggqpedKQRLLYLSRDDLMRHEAAGVTTELFPKRATMAGVEMALTYHF 919
Cdd:pfam11898 81 DETLFDFYDARLPADVVSGRHFDKWWKKARRE------DPDLLDLTREDLLRHEADAVTEEDFPDTWGLGGLRLPLSYRF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 920 EPGTPRDGVTLAVPLYALNQVDARRCEWLVPGMLKEKVQLLLKSLPQKLRRHCVPLPEYAAGFVERMGRERFGAGGLVEA 999
Cdd:pfam11898 155 EPGAEDDGVTVTVPLALLNQVSPERFDWLVPGLLEEKVTALIKSLPKALRRNFVPAPDFARAALARLEREPPGDGPLLDA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1000 LIADVRGETQVAMKTADFKLETLPAHLFMNFKVIDEHGRQLAMGRNLAQLRQELGAQAQQQFQKIAAASTIAAGgdadag 1079
Cdd:pfam11898 235 LARALRRLTGVRVPPDDWDLDALPPHLRMNFRVVDDRGKVLAEGRDLAALKARLAGQARAAFAAAAAASLERTG------ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1080 qpvgqapaaagpagapgrgpkpakgaapqtsapaeagatalyenLTTWNFGKLPELLEIRRRGQTLYGYPALVDRGTHCD 1159
Cdd:pfam11898 309 --------------------------------------------LTSWDFGDLPETVELKRGGQEVTGYPALVDEGDSVA 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1160 VEVFDSPEEAARIHRAGLRRLFALQLKEPIKFLEKNLPGLREMAMQYMSLGTQDELRDQLIDTALDRACLQ-DPLPDDDA 1238
Cdd:pfam11898 345 LRLFDTPAEAAAAHRAGVRRLLLLALPSPVKYLEKNLPNLQKLALAYNPLGSVEALVDDLIAAALDRLFLEpVPLPRDEA 424
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1239 SFHARRDEGRSRLNLLAQEIARLVGQVLAEYAGLVKKLAQAKPFAQ--AHADLQQQLAALVGKRFVIDTPYAQLAHFPRY 1316
Cdd:pfam11898 425 AFEALLEEVRARLPDTAQEVARLVEEILAAYQALRKRLKGKKSLALaaALADIRAQLDRLVPPGFVAATPWERLAHLPRY 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 1317 LKGIALRIDKLKADPARDAKQSADLLPLAQQYQRAVSQR--GGVADPRLAEFRWLLEELRISLFAQELRTPMPVSVKRLH 1394
Cdd:pfam11898 505 LKAIELRLEKLPADPARDRQRMAEVAPLEQRYQALLAKLpaGRPDPEELEEFRWMLEELRVSLFAQELGTPYPVSEKRLE 584
|
...
gi 1600237547 1395 KVW 1397
Cdd:pfam11898 585 KAW 587
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
103-610 |
6.39e-96 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 327.88 E-value: 6.39e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPkicldLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:TIGR01970 1 LPIHAVLPALRDALAAHPQVVLEAPPGAGKSTAVP-----LALLDAPGIGGKIIMLEPRRLAARSAAQRLASQLGEAVGQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPR-RPDLKLIVTSAT 261
Cdd:TIGR01970 76 TVGYRVRGENKVSRRTRLEVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSlREDLKILAMSAT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 262 IDADRFARHFGTderpAPVIEVSGRLYPVEMRYRPVAEDRPavknaegtggrdrvktareaerdLMDAIVDAVDELCREG 341
Cdd:TIGR01970 156 LDGERLSSLLPD----APVVESEGRSFPVEIRYLPLRGDQR-----------------------LEDAVSRAVEHALASE 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 342 PGDVLVFLPGEREIREAAEALRKHHPPHTEILPLFARLSAADQDKVFK--ASNARRIVLATNVAETSLTVPGIRYVVDTG 419
Cdd:TIGR01970 209 TGSILVFLPGQAEIRRVQEQLAERLDSDVLICPLYGELSLAAQDRAIKpdPQGRRKVVLATNIAETSLTIEGIRVVIDSG 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 420 LARVKRYSYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYEESDYQARARFTDPEILRSSLASVILRMKSLHLTA 499
Cdd:TIGR01970 289 LARVARFDPKTGITRLETVRISQASATQRAGRAGRLEPGVCYRLWSEEQHQRLPAQDEPEILQADLSGLALELAQWGAKD 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 500 IESFPFLEPPPGRAIADGYQLLNELGAVDDDNALTPLGRELARLPLDPRVGRMILAARDQQSLREVLIIASALSVQD-PR 578
Cdd:TIGR01970 369 PSDLRWLDAPPSVALAAARQLLQRLGALDAQGRLTAHGKAMAALGCHPRLAAMLLSAHSTGLAALACDLAALLEERGlPR 448
|
490 500 510
....*....|....*....|....*....|..
gi 1600237547 579 DRPIEAQEQADQAHRRFADERSEFLQWLKIWA 610
Cdd:TIGR01970 449 QGGADLMNRLHRLQQGRQGRGQRAQQLAKKLR 480
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
103-283 |
2.45e-88 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 283.96 E-value: 2.45e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTgligHTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGIRGLIG----HTQPRRLAARSVAERIAEELKTELGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17989 77 AVGYKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATI 156
|
170 180
....*....|....*....|.
gi 1600237547 263 DADRFARHFGTderpAPVIEV 283
Cdd:cd17989 157 DAERFSRHFNN----APIIEV 173
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
102-559 |
2.08e-85 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 297.61 E-value: 2.08e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 102 SLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLP-----------KICLDlgrglgaggtglightQPRRLAASSTGR 170
Cdd:PRK11664 3 SLPVAAVLPELLTALKTAPQVLLKAPTGAGKSTWLPlqllqhggingKIIML----------------EPRRLAARNVAQ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 171 RIAEELGTPFGEVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEI---L 247
Cdd:PRK11664 67 RLAEQLGEKPGETVGYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVqqgL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 248 prRPDLKLIVTSATIDADRFARHFgtderP-APVIEVSGRLYPVEMRYRPVAEDRPavknaegtggrdrvktareaerdL 326
Cdd:PRK11664 147 --RDDLKLLIMSATLDNDRLQQLL-----PdAPVIVSEGRSFPVERRYQPLPAHQR-----------------------F 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 327 MDAIVDAVDELCREGPGDVLVFLPGEREIREAAEALRKHHPPHTEILPLFARLSAADQDKVFKASNA--RRIVLATNVAE 404
Cdd:PRK11664 197 DEAVARATAELLRQESGSLLLFLPGVGEIQRVQEQLASRVASDVLLCPLYGALSLAEQQKAILPAPAgrRKVVLATNIAE 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 405 TSLTVPGIRYVVDTGLARVKRYSYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYEESDYQARARFTDPEILRSS 484
Cdd:PRK11664 277 TSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQASMTQRAGRAGRLEPGICLHLYSKEQAERAAAQSEPEILHSD 356
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1600237547 485 LASVILRMKSLHLTAIESFPFLEPPPGRAIADGYQLLNELGAVDDDNALTPLGRELARLPLDPRVGRMILAARDQ 559
Cdd:PRK11664 357 LSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRLLQQLGALDGQGRLTARGRKMAALGNDPRLAAMLVAAKED 431
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
119-283 |
2.19e-65 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 218.10 E-value: 2.19e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 119 HQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLigHTQPRRLAASSTGRRIAEELGTPFGEVVGYKVRFTDNLAPGA 198
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAKGGKGRIV--CTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 199 SVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATIDADRFARHFGTderpA 278
Cdd:cd17917 79 RIKFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGG----A 154
|
....*
gi 1600237547 279 PVIEV 283
Cdd:cd17917 155 PVIHI 159
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
288-464 |
5.30e-64 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 214.70 E-value: 5.30e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 288 YPVEMRYRPVAEDRPAVKNAEgtggrdrvktareAERDLMDAIVDAVDELCR-EGPGDVLVFLPGEREIREAAEALRKH- 365
Cdd:cd18791 1 FPVEVYYLEDILELLGISSEK-------------EDPDYVDAAVRLILQIHRtEEPGDILVFLPGQEEIERLCELLREEl 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 366 ---HPPHTEILPLFARLSAADQDKVFKAS--NARRIVLATNVAETSLTVPGIRYVVDTGLARVKRYSYRNKVEQLQVESI 440
Cdd:cd18791 68 lspDLGKLLVLPLHSSLPPEEQQRVFEPPppGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWI 147
|
170 180
....*....|....*....|....
gi 1600237547 441 SQAAANQRAGRCGRVADGICIRLY 464
Cdd:cd18791 148 SKASAEQRAGRAGRTRPGKCYRLY 171
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
103-272 |
4.23e-53 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 183.82 E-value: 4.23e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGlighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGVELGE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17983 77 EVGYAIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATM 156
|
170
....*....|
gi 1600237547 263 DADRFARHFG 272
Cdd:cd17983 157 DADKFADFFG 166
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
103-283 |
2.35e-52 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 182.17 E-value: 2.35e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPK-ICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTpFG 181
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQfLYEAGFGSPESDNPGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 182 EVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPD--------- 252
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRAKlylqdqtvk 159
|
170 180 190
....*....|....*....|....*....|..
gi 1600237547 253 -LKLIVTSATIDADRFARHFGTDERPAPVIEV 283
Cdd:cd17982 160 pLKLVIMSATLRVEDFTENKLLFPRPPPVIKV 191
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
103-283 |
8.72e-52 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 180.30 E-value: 8.72e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIghTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17973 13 LPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELPHQPKKLVAC--TQPRRVAAMSVAQRVAEEMDVKLGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17973 91 EVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPDLKLIVMSATL 170
|
170 180
....*....|....*....|.
gi 1600237547 263 DADRFARHFGTderpAPVIEV 283
Cdd:cd17973 171 DAGKFQKYFDN----APLLKV 187
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
103-281 |
1.54e-51 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 179.47 E-value: 1.54e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGlighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFARGGMIGI----TQPRRVAAVSVAKRVAEEMGVELGQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRR-----PDLKLIV 257
Cdd:cd17978 77 LVGYSVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRkeqklSPLKVII 156
|
170 180
....*....|....*....|....
gi 1600237547 258 TSATIDADRFARHFGTderpAPVI 281
Cdd:cd17978 157 MSATLDADLFSEYFNG----APVL 176
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
101-271 |
5.11e-51 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 178.06 E-value: 5.11e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 101 ESLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGlighTQPRRLAASSTGRRIAEELGTPF 180
Cdd:cd17971 4 ESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYTSRGKIGC----TQPRRVAAMSVAKRVAEEFGCCL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 181 GEVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSA 260
Cdd:cd17971 80 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTSA 159
|
170
....*....|.
gi 1600237547 261 TIDADRFARHF 271
Cdd:cd17971 160 TLDAVKFSQYF 170
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
103-277 |
1.51e-48 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 170.76 E-value: 1.51e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEAGYTKGGGKIGC---TQPRRVAAMSVAARVAEEMGVKLGN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17974 78 EVGYSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSATM 157
|
170
....*....|....*
gi 1600237547 263 DADRFARHFgtDERP 277
Cdd:cd17974 158 DAEKFSAFF--DDAP 170
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
103-275 |
2.77e-48 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 170.34 E-value: 2.77e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEAGWTAGGRVVGC---TQPRRVAAVTVAGRVAEEMGAVLGH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGA-SVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSAT 261
Cdd:cd17980 78 EVGYCIRFDDCTDPQAtRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASAT 157
|
170
....*....|....
gi 1600237547 262 IDADRFARHFGTDE 275
Cdd:cd17980 158 LDAEKFRDFFNQNE 171
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
103-283 |
1.67e-42 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 153.37 E-value: 1.67e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGgtglighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGFRHIAC-------TQPRRIACISLAKRVAFESLNQYGS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17979 74 KVAYQIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATI 153
|
170 180
....*....|....*....|.
gi 1600237547 263 DADRFARHFGTderpAPVIEV 283
Cdd:cd17979 154 NIELFSGYFEG----APVVQV 170
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
103-272 |
2.47e-41 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 150.00 E-value: 2.47e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGlighTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGV----TQPRRVAAISVAQRVAEEMKCTLGS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILP-----RRPDLKLIV 257
Cdd:cd17984 77 KVGYQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLLKKLFQekspnRKEHLKVVV 156
|
170
....*....|....*
gi 1600237547 258 TSATIDADRFARHFG 272
Cdd:cd17984 157 MSATLELAKLSAFFG 171
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
103-283 |
1.09e-40 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 148.45 E-value: 1.09e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELG--TPF 180
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFILDDAIERGKGSSCRIVCTQPRRISAISVAERVAAERAesCGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 181 GEVVGYKVRFTDNLA-PGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTS 259
Cdd:cd17981 81 GNSTGYQIRLESRKPrKQGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKVILMS 160
|
170 180
....*....|....*....|....
gi 1600237547 260 ATIDADRFARHFGTderpAPVIEV 283
Cdd:cd17981 161 ATLNAEKFSDYFNN----CPMIHI 180
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
103-283 |
5.63e-40 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 146.48 E-value: 5.63e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEDYVLRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAP-GASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSAT 261
Cdd:cd17976 81 NVGYQVRLESRPPPrGGALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170 180
....*....|....*....|..
gi 1600237547 262 IDADRFARHFGTderpAPVIEV 283
Cdd:cd17976 161 GDNQRLSRYFGG----CPVVRV 178
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
103-271 |
1.32e-36 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 136.97 E-value: 1.32e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPK-ICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFG 181
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQfLLEDLLLNGGTAQKCNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 182 -----EVVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLI 256
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170
....*....|....*
gi 1600237547 257 VTSATIDADRFARHF 271
Cdd:cd17975 161 LMSATVDCEKFSSYF 175
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
103-283 |
2.37e-36 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 135.73 E-value: 2.37e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIghTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDCYANGIPCRIFC--TQPRRLAAIAVAERVAAERGEKIGQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQT-DPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSAT 261
Cdd:cd17987 79 TVGYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSSAA 158
|
170 180
....*....|....*....|..
gi 1600237547 262 IDADRFARHFGTderpAPVIEV 283
Cdd:cd17987 159 LDVNLFIRYFGS----CPVIYI 176
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
101-283 |
1.12e-35 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 136.12 E-value: 1.12e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 101 ESLPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPF 180
Cdd:cd17972 57 ELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEEV 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 181 GEVVGYKVRFTDNLA-PGASVKLMTDGILLAETQTDplLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTS 259
Cdd:cd17972 137 GKSCGYSVRFESVLPrPHASILFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILMS 214
|
170 180
....*....|....*....|....
gi 1600237547 260 ATIDADRFARHFGTderpAPVIEV 283
Cdd:cd17972 215 ATIDTSMFCEYFFN----CPVIEV 234
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
103-283 |
1.06e-34 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 131.08 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIghTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILDHYYKRGKYCNIVV--TQPRRIAAISIARRVSQEREWTLGS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPD-LKLIVTSAT 261
Cdd:cd17988 79 LVGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRhVKIILMSAT 158
|
170 180
....*....|....*....|..
gi 1600237547 262 IDADRFARHFGTDERPAPVIEV 283
Cdd:cd17988 159 ISCKEFADYFTTPNNPAYVFEV 180
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
103-283 |
2.66e-34 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 129.96 E-value: 2.66e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNSLQGPPLPVANIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170 180
....*....|....*....|.
gi 1600237547 263 DADRFARHFGTderpAPVIEV 283
Cdd:cd17985 161 NAELFSDYFNS----CPVIHI 177
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
103-283 |
4.16e-34 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 129.37 E-value: 4.16e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPkiclDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVP----LALLAELWIAGGKIIVLEPRRVAARAAARRLATLLGEAPGE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILP-RRPDLKLIVTSAT 261
Cdd:cd17990 77 TVGYRVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQlLRDDLRLLAMSAT 156
|
170 180
....*....|....*....|..
gi 1600237547 262 IDADRFARHFGTderpAPVIEV 283
Cdd:cd17990 157 LDGDGLAALLPE----APVVES 174
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
523-606 |
7.20e-27 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 105.04 E-value: 7.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 523 ELGAVDDDNALTPLGRELARLPLDPRVGRMILAARDQQSLREVLIIASALSVQDPRDRpiEAQEQADQAHRRFADERSEF 602
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPRPK--EKREDADAARRRFADPESDH 78
|
....
gi 1600237547 603 LQWL 606
Cdd:smart00847 79 LTLL 82
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
103-283 |
9.09e-26 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 105.29 E-value: 9.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 103 LPVSGKRDEIARAIAGHQVVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGhTQPRRLAASSTGRRIAEELGTPFGE 182
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVC-TQVHKQTAVWLALRVADEMDVNIGH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 183 VVGYKVRFTDNLAPGASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATI 262
Cdd:cd17977 80 EVGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPH 159
|
170 180
....*....|....*....|.
gi 1600237547 263 DADRFARHFGTderpAPVIEV 283
Cdd:cd17977 160 LSSKLLSYYGN----VPLIEV 176
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
121-283 |
1.61e-24 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 101.90 E-value: 1.61e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 121 VVIVCGETGSGKTTQLPKICLDLGRGLGAGGTGLIGhTQPRRLAASSTGRRIAEELGTPFGEVVGYKVRFTDNLAPGASV 200
Cdd:cd17986 20 IVLVSGEPGSGKSTQVPQWCAEFALSRGFQKGQVTV-TQPHPLAARSLALRVADEMDLNLGHEVGYSIPQEDCTGPNTIL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 201 KLMTDGILLAETQTDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRPDLKLIVTSATIDADRFARHFGTderpAPV 280
Cdd:cd17986 99 RFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPALEPKLRAFWGN----PPV 174
|
...
gi 1600237547 281 IEV 283
Cdd:cd17986 175 VHV 177
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
519-610 |
1.74e-21 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 90.76 E-value: 1.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 519 QLLNELGAVDDDNALTPLGRELARLPLDPRVGRMILAARDQQSLREVLIIASALSVQDPRDRPIEAQEQADQAHRRfADE 598
Cdd:pfam04408 3 ELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRDPFVQPNFLDPRSAAKAAR-RRR 81
|
90
....*....|..
gi 1600237547 599 RSEFLQWLKIWA 610
Cdd:pfam04408 82 RAADEKARAKFA 93
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
112-275 |
2.58e-18 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 84.85 E-value: 2.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 112 IARAIAGHQVVIVCGETGSGKTTQLPKICldlGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTPFGEVVGY----- 186
Cdd:smart00487 17 IEALLSGLRDVILAAPTGSGKTLAALLPA---LEALKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGLyggds 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 187 -KVRFTDNLAPGASVKLMTDGILLAETQTDPL-LKAYDTLIIDEAHERS--LNIDFLLGYLKEIlprRPDLKLIVTSATI 262
Cdd:smart00487 94 kREQLRKLESGKTDILVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLLdgGFGDQLEKLLKLL---PKNVQLLLLSATP 170
|
170
....*....|....*
gi 1600237547 263 --DADRFARHFGTDE 275
Cdd:smart00487 171 peEIENLLELFLNDP 185
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
111-465 |
3.89e-12 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 70.78 E-value: 3.89e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 111 EIARAIAGHQVVIVCGETGSGKTTQLPKIC----------LDLGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGtpF 180
Cdd:PHA02653 171 KIFEAWISRKPVVLTGGTGVGKTSQVPKLLlwfnylfggfDNLDKIDPNFIERPIVLSLPRVALVRLHSITLLKSLG--F 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 181 GEVVGYKV--RFTD------NLAPGAsvklmtDGILLAETQ-TDPLLKAYDTLIIDEAHERSLNIDFLLGYLKEILPRRP 251
Cdd:PHA02653 249 DEIDGSPIslKYGSipdeliNTNPKP------YGLVFSTHKlTLNKLFDYGTVIIDEVHEHDQIGDIIIAVARKHIDKIR 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 252 DLKLIvtSATI--DADRFARHFgtdERPAPVIEVSGRLYPVEMRYrpvaedrpaVKNAegTGGRDRVKTAREAERDLMDA 329
Cdd:PHA02653 323 SLFLM--TATLedDRDRIKEFF---PNPAFVHIPGGTLFPISEVY---------VKNK--YNPKNKRAYIEEEKKNIVTA 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 330 IVDavdelCREGPG-DVLVFLPGEREIREAAEALRKHHPP------HTEILPLFARLSaadqdKVFkASNARRIVLATNV 402
Cdd:PHA02653 387 LKK-----YTPPKGsSGIVFVASVSQCEEYKKYLEKRLPIydfyiiHGKVPNIDEILE-----KVY-SSKNPSIIISTPY 455
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1600237547 403 AETSLTVPGIRYVVDTGlaRVkrysYRNKVEQLQVESISQAAANQRAGRCGRVADGICIRLYE 465
Cdd:PHA02653 456 LESSVTIRNATHVYDTG--RV----YVPEPFGGKEMFISKSMRTQRKGRVGRVSPGTYVYFYD 512
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
334-455 |
2.02e-10 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 59.15 E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 334 VDELCREGPGDVLVFLPGEREIreAAEALRKHHppHTEILPLFARLSAADQDKVFKA--SNARRIVLATNVAETSLTVPG 411
Cdd:pfam00271 7 LELLKKERGGKVLIFSQTKKTL--EAELLLEKE--GIKVARLHGDLSQEEREEILEDfrKGKIDVLVATDVAERGLDLPD 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1600237547 412 IRYVVDTGLARvkrysyrnkveqlqvesiSQAAANQRAGRCGRV 455
Cdd:pfam00271 83 VDLVINYDLPW------------------NPASYIQRIGRAGRA 108
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
699-747 |
4.88e-10 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 57.26 E-value: 4.88e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1600237547 699 KFYLWPGSVLAKKAG---RWVMAAELVETSRLYARCLAKIEPEWVEKIGAHL 747
Cdd:pfam07717 31 RVFIHPSSVLFNEKTfppEWVVYQELVETTKVYIRTVTAISPEWLLLFAPHI 82
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
359-454 |
1.28e-09 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 56.07 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 359 AEALRKHHpphTEILPLFARLSAADQDKVFKA--SNARRIVLATNVAETSLTVPGIRYVVDTGLarvkrysyrnkveqlq 436
Cdd:smart00490 4 AELLKELG---IKVARLHGGLSQEEREEILDKfnNGKIKVLVATDVAERGLDLPGVDLVIIYDL---------------- 64
|
90
....*....|....*...
gi 1600237547 437 veSISQAAANQRAGRCGR 454
Cdd:smart00490 65 --PWSPASYIQRIGRAGR 80
|
|
| BRR2 |
COG1204 |
Replicative superfamily II helicase [Replication, recombination and repair]; |
222-556 |
9.38e-06 |
|
Replicative superfamily II helicase [Replication, recombination and repair];
Pssm-ID: 440817 [Multi-domain] Cd Length: 529 Bit Score: 49.89 E-value: 9.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 222 DTLIIDEAH-----ERSLNIDFLLGYLKEilpRRPDLKLIVTSATID-ADRFAR-----HFGTDERPAPVIEvsGRLYPV 290
Cdd:COG1204 139 DLVVVDEAHliddeSRGPTLEVLLARLRR---LNPEAQIVALSATIGnAEEIAEwldaeLVKSDWRPVPLNE--GVLYDG 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 291 EMRYRPVAE--DRPAVKNAE---GTGG---------RDRVKTAREAeRDLMDAIVDAVDELCREGPGDVLVFLPGEREIR 356
Cdd:COG1204 214 VLRFDDGSRrsKDPTLALALdllEEGGqvlvfvssrRDAESLAKKL-ADELKRRLTPEEREELEELAEELLEVSEETHTN 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 357 EA-AEALRK----HHpphteilplfARLSAADQDKV---FKASNARRIVlATnvaeTSLT----VPgIRYVVdtglarVK 424
Cdd:COG1204 293 EKlADCLEKgvafHH----------AGLPSELRRLVedaFREGLIKVLV-AT----PTLAagvnLP-ARRVI------IR 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 425 RYsYRNKVEQLQVESISQAAAnqRAGRCGR--VADGICIRLYEESDYQARARF--TDPEILRSSLAS-VILRMKSLHLTA 499
Cdd:COG1204 351 DT-KRGGMVPIPVLEFKQMAG--RAGRPGYdpYGEAILVAKSSDEADELFERYilGEPEPIRSKLANeSALRTHLLALIA 427
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1600237547 500 ---------IESF--------PFLEPPPGRAIADGYQLLNELGAVDDDN---ALTPLGRELARLPLDPRVGRMILAA 556
Cdd:COG1204 428 sgfansreeLLDFlentfyayQYDKGDLEEVVDDALEFLLENGFIEEDGdrlRATKLGKLVSRLYIDPLTAAELVDG 504
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
112-265 |
1.68e-05 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 46.47 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 112 IARAIAGHQVvIVCGETGSGKTT--QLPKIcldlgrglgAGGTGLIGHTQ-----PRR-LAasstgRRIAEELgTPFGEV 183
Cdd:pfam00270 8 IPAILEGRDV-LVQAPTGSGKTLafLLPAL---------EALDKLDNGPQalvlaPTReLA-----EQIYEEL-KKLGKG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 184 VGYKVRFTDNLAP---------GASVKLMTDGILLAETQTDPLLKAYDTLIIDEAHeRSLNIDFlLGYLKEILPR-RPDL 253
Cdd:pfam00270 72 LGLKVASLLGGDSrkeqleklkGPDILVGTPGRLLDLLQERKLLKNLKLLVLDEAH-RLLDMGF-GPDLEEILRRlPKKR 149
|
170
....*....|..
gi 1600237547 254 KLIVTSATIDAD 265
Cdd:pfam00270 150 QILLLSATLPRN 161
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
122-261 |
1.02e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 40.85 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1600237547 122 VIVCGETGSGKTTQLPKIcldlGRGLGAGGTGLIGHTQPRRLAASSTGRRIAEELGTpfGEVVGYKVRFTD------NLA 195
Cdd:cd00046 4 VLITAPTGSGKTLAALLA----ALLLLLKKGKKVLVLVPTKALALQTAERLRELFGP--GIRVAVLVGGSSaeerekNKL 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1600237547 196 PGASVKLMT-DGILLAETQTDPL-LKAYDTLIIDEAHERSLNIDFLLGYLKEILPR-RPDLKLIVTSAT 261
Cdd:cd00046 78 GDADIIIATpDMLLNLLLREDRLfLKDLKLIIVDEAHALLIDSRGALILDLAVRKAgLKNAQVILLSAT 146
|
|
| |
