|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
1-316 |
0e+00 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 606.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 1 MDVPWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELFGEeNWRDNFLELNSSDERG 80
Cdd:PRK00440 3 MEEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGE-DWRENFLELNASDERG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 81 IDVIRTKVKNFARTKPIGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPL 160
Cdd:PRK00440 82 IDVIRNKIKEFARTAPVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSPL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 161 KKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIVYKVSSRARPTEIRQMMNLALEG 240
Cdd:PRK00440 162 KKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELALNG 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 241 KFNEARDLLYKLMIDWGMSGEDVLVQMFREIPNLDIDERKKVAVLEAIGECDFRIVEGANERIQLSALLAKLGMLG 316
Cdd:PRK00440 242 DFTEAREKLRDLMIDYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKLALLG 317
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
44-316 |
1.73e-159 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 466.24 E-value: 1.73e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 44 PPGVGKTTAALCLARELFGEeNWRDNFLELNSSDERGIDVIRTKVKNFARTKPIGDAPFKIIFLDESDALTSDAQNALRR 123
Cdd:PRK04132 574 PTVLHNTTAALALARELFGE-NWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRR 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 124 TMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL 203
Cdd:PRK04132 653 TMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINIL 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 204 QTAASVSKNITDEIVYKVSSRARPTEIRQMMNLALEGKFNEARDLLYKLMIDWGMSGEDVLVQMFREIPNLDIDERKKVA 283
Cdd:PRK04132 733 QAAAALDDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHREVFNLPIDEPKKVE 812
|
250 260 270
....*....|....*....|....*....|...
gi 1584888649 284 VLEAIGECDFRIVEGANERIQLSALLAKLGMLG 316
Cdd:PRK04132 813 LADKIGEYNFRLVEGANEMIQLEALLAQFTLMG 845
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
3-312 |
2.45e-110 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 323.22 E-value: 2.45e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 3 VPWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELFGEeNWRDNFLELNSSDERGID 82
Cdd:PLN03025 1 LPWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGP-NYKEAVLELNASDDRGID 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 83 VIRTKVKNFARTK---PIGDapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSP 159
Cdd:PLN03025 80 VVRNKIKMFAQKKvtlPPGR--HKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 160 LKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIVYKVSSRARPTEIRQMMNLALE 239
Cdd:PLN03025 158 LSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLK 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 240 GKFNEARDLLyKLMIDWGMSGEDVLVQMFREIPNLDIDERKKVAVLEAIGECDFRIVEGANERIQLSALLAKL 312
Cdd:PLN03025 238 GKFDDACDGL-KQLYDLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKL 309
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
5-313 |
2.97e-104 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 308.46 E-value: 2.97e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 5 WVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELFGEeNWRDNFLELNSSD--ERG-- 80
Cdd:PRK12402 5 WTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGD-PWENNFTEFNVADffDQGkk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 81 ----------------------IDVIRTKVKNFARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSC 138
Cdd:PRK12402 84 ylvedprfahflgtdkrirsskIDNFKHVLKEYASYRPL-SADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIAT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 139 NYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIV 218
Cdd:PRK12402 163 RQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITMEAA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 219 YKVSSRA-RPTEIRQMMNLALEGKFNEARDLLYKLMIDWGMSGEDVLVQMfREIPNLDIDERKKVAVLEAIGECDFRIVE 297
Cdd:PRK12402 243 YEALGDVgTDEVIESLLDAAEAGDFTDARKTLDDLLIDEGLSGGEVLEEL-LRVARSRYRGDNLARLHRLAADADARLTD 321
|
330
....*....|....*.
gi 1584888649 298 GANERIQLSALLAKLG 313
Cdd:PRK12402 322 GANDRIQLEALLAELG 337
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
20-315 |
7.00e-78 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 239.49 E-value: 7.00e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 20 HEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEeNWRD------------------NFLELN---SSD 77
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCE-NPEGgkacgqchsrlmaagnhpDLLELNpeeKSD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 78 ERGIDVIRtKVKNFARTKPIGdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRF 157
Cdd:COG0470 80 QIGIDQIR-ELGEFLSLTPLE-GGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 158 SPLKKEDIAKKIKEicekEGltIDNKGLDAIIYVSEGDLRKAINVLQTAAsvSKNITDEIVYKVSSRARPTEirqMMNLA 237
Cdd:COG0470 158 RPPSEEEALAWLRE----EG--VDEDALEAILRLAGGDPRAAINLLQALA--GRKELLEDLAALLSRDRALE---LLDAL 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 238 LEGKFNEARDLLYKLMIDwgmsgedvlvqmfrEIPnLDIDERKKVAVLEAIGECDFRIVEGANERIQLSALLAKLGML 315
Cdd:COG0470 227 LKAEALELLDWLLKWLLD--------------NLP-LEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKLGRL 289
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
5-314 |
1.34e-52 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 175.18 E-value: 1.34e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 5 WVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEenwrdnFLELNSSDERgIDV 83
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNmLLHSPSPGTGKTTVAKALCNEVGAE------VLFVNGSDCR-IDF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 84 IRTKVKNFARTKPIgDAPFKIIFLDESD-ALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKK 162
Cdd:PHA02544 84 VRNRLTRFASTVSL-TGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFGVPTK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 163 ED-------IAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASvskniTDEIVYKVSSRARPTEIRQMMN 235
Cdd:PHA02544 163 EEqiemmkqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYAS-----TGKIDAGILSEVTNSDIDDVVE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 236 lALEGK-FNEARDLLYKLMIDwgmsGEDVLVQMFREI-PNLDIDErkKVAVLEAIGECDFRIVEGANERIQLSALLAKLG 313
Cdd:PHA02544 238 -ALKAKdFKAVRALAPNYAND----YASFVGKLYDELyPQVTPPS--IIRLIEIIGENNQYHGFAADQEIHLLYLLTQLM 310
|
.
gi 1584888649 314 M 314
Cdd:PHA02544 311 L 311
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
2-258 |
3.02e-49 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 170.87 E-value: 3.02e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 2 DVPWVEKYRPKRLDEITGHEEIVKRLKNYVKR--KSLPH--LLFSGPPGVGKTTAALCLARELFGEenwrdnFLELNSSD 77
Cdd:PRK04195 1 MMPWVEKYRPKTLSDVVGNEKAKEQLREWIESwlKGKPKkaLLLYGPPGVGKTSLAHALANDYGWE------VIELNASD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 78 ERGIDVIRTKVKNFARTKPIGDAPFKIIFLDESDAL--TSDAQNAlrrtmemySDVCRFILSCNYPsrII---------- 145
Cdd:PRK04195 75 QRTADVIERVAGEAATSGSLFGARRKLILLDEVDGIhgNEDRGGA--------RAILELIKKAKQP--IIltandpydps 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 146 -PPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIVYKVSSR 224
Cdd:PRK04195 145 lRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDVKTLGRR 224
|
250 260 270
....*....|....*....|....*....|....*
gi 1584888649 225 ARPTEIRQMMNLALEGK-FNEARDLLYKLMIDWGM 258
Cdd:PRK04195 225 DREESIFDALDAVFKARnADQALEASYDVDEDPDD 259
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
11-312 |
2.00e-41 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 146.88 E-value: 2.00e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 11 PKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDN----------FLELNSSD-- 77
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILAKALNCENGPTGEpcgecescraIAAGSHPDvi 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 78 -------ERGIDVIRTKVKNfARTKPIgDAPFKIIFLDESDALTSDAQNAL--------RRTMemysdvcrFILSCNYPS 142
Cdd:COG2812 86 eidaeasNIGVDDIRELIEK-VSYAPV-EGRYKVYIIDEAHMLTTEAFNALlktleeppPHVV--------FILATTEPQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 143 RIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQtaasvsknitDEIVYKVs 222
Cdd:COG2812 156 KLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLD----------QAIAFGL- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 223 sRARPTEIRQMMNLALEGKFNEARDLLYKLmIDWGMSGEDVLVQM---FREI------PNLDI----DERKKVA------ 283
Cdd:COG2812 225 -LDRRELLLDLLEALLAGDVAALLALAEEL-AKRGRDLKRFLDDLlslLRDLlllklgPDAELlvneDERERLQelarrl 302
|
330 340 350
....*....|....*....|....*....|....*.
gi 1584888649 284 -------VLEAIGECDFRIVEGANERIQLSALLAKL 312
Cdd:COG2812 303 sperllrAIQILLEARRELERNVNPRLALEMLLLRL 338
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
1-282 |
5.54e-40 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 146.12 E-value: 5.54e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 1 MDVPWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELF------GE-----ENWRD 68
Cdd:PRK14953 2 MYIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHaYIFAGPRGTGKTTIARILAKVLNclnpqeGEpcgkcENCVE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 -------NFLELNSSDERGIDVIRTkVKNFARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYP 141
Cdd:PRK14953 82 idkgsfpDLIEIDAASNRGIDDIRA-LRDAVSYTPI-KGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 142 SRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSK-NITDEIVYK 220
Cdd:PRK14953 160 DKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEgKVTIKVVEE 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1584888649 221 VSSRARPTEIRQMMNLALEGKFNEARDLL-------YKLMIDWgmsgEDVLVQMFREIPNLDIDERKKV 282
Cdd:PRK14953 240 FLGIVSQESVRKFLNLLLESDVDEAIKFLrtleekgYNLNKFW----KQLEEEIRNILLNKSLKNPEEV 304
|
|
| dnaX_nterm |
TIGR02397 |
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ... |
8-274 |
6.73e-40 |
|
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274111 [Multi-domain] Cd Length: 355 Bit Score: 143.09 E-value: 6.73e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL-------------------FGEENWR 67
Cdd:TIGR02397 7 KYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHaYLFSGPRGTGKTSIARIFAKALncqngpdgepcnecesckeINSGSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 DnFLELNSSDERGIDVIRTKVKN--FARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRII 145
Cdd:TIGR02397 87 D-VIEIDAASNNGVDDIREILDNvkYAPSS----GKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 146 PPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSK-NITDEIVYKVSSR 224
Cdd:TIGR02397 162 ATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNgKITYEDVNELLGL 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1584888649 225 ARPTEIRQMMNLALEGKFNEARDLLYKLmIDWGMSGEDVLVQMFREIPNL 274
Cdd:TIGR02397 242 VDDEKLIELLEAILNKDTAEALKILDEI-LESGVDPEKFLEDLIEILRDL 290
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
8-278 |
7.76e-33 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 126.42 E-value: 7.76e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENW---------------RDNF- 70
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVARILAKSLNCENRKgvepcnecracrsidEGTFm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 71 --LELNSSDERGIDVIRtKVKNFARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPI 148
Cdd:PRK14962 87 dvIELDAASNRGIDEIR-KIRDAVGYRPM-EGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 149 QSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEIVYKVSSRARP 227
Cdd:PRK14962 165 ISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLeQVWKFSEGKITLETVHEALGLIPI 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 228 TEIRQMmnlaLEGKFNEARDLLYKLMIDWGMSGED--VLVQMFREIPNLDIDE 278
Cdd:PRK14962 245 EVVRDY----INAIFNGDVKRVFTVLDDVYYSGKDyeVLIQQAIEDLVEDLER 293
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
7-225 |
1.24e-31 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 122.12 E-value: 1.24e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 7 EKYRPKRLDEITGHEEIV---KRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELfgeenwRDNFLELNSSDErGIDV 83
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT------DAPFEALSAVTS-GVKD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 84 IRTKVKNFARTKPIGDAPfkIIFLDESDALTSDAQNALRRTMEmySDVCRFILSC--NyPS-RIIPPIQSRCAIFRFSPL 160
Cdd:PRK13342 77 LREVIEEARQRRSAGRRT--ILFIDEIHRFNKAQQDALLPHVE--DGTITLIGATteN-PSfEVNPALLSRAQVFELKPL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 161 KKEDI---AKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIVYKVSSRA 225
Cdd:PRK13342 152 SEEDIeqlLKRALEDKERGLVELDDEALDALARLANGDARRALNLLELAALGVDSITLELLEEALQKR 219
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
8-290 |
2.67e-30 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 117.67 E-value: 2.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL------FGEENWRDNFLELNSSDERG 80
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARKInqpgydDPNEDFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 81 IDVIRTKVKNFARTKPIGDapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPL 160
Cdd:PRK14970 90 VDDIRNLIDQVRIPPQTGK--YKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKRI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 161 KKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAAS-VSKNITDEIVYKVSSRARPTEIRQMMNLALE 239
Cdd:PRK14970 168 TIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTfCGKNITRQAVTENLNILDYDTYINVTDLILE 247
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 240 GKFNEARdLLYKLMIDWGMSGEDVLVQMFREIPNLDIDERKKVAVLEAIGE 290
Cdd:PRK14970 248 NKIPELL-LAFNEILRKGFDGHHFIAGLASHFRDLMVSKTPATIALLEVGE 297
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
225-311 |
2.24e-29 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 107.56 E-value: 2.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 225 ARPTEIRQMMNLALEGKFNEARDLLYKLMIDWGMSGEDVLVQMFREIPNLDIDERKKVAVLEAIGECDFRIVEGANERIQ 304
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVRELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*..
gi 1584888649 305 LSALLAK 311
Cdd:pfam08542 81 LSALLAA 87
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
8-214 |
7.15e-28 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 113.33 E-value: 7.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAR-----------ELFGE--------ENWR 67
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTCARIFAKtincqnltadgEACNEcescvafnEQRS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 DNFLELNSSDERGIDVIRTKVKNFARTKPIGDapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPP 147
Cdd:PRK14971 90 YNIHELDAASNNSVDDIRNLIEQVRIPPQIGK--YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPT 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 148 IQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVS-KNIT 214
Cdd:PRK14971 168 ILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTgGNIT 235
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
8-269 |
3.42e-27 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 111.12 E-value: 3.42e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL------FGE-----ENWRD------- 68
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQGKISHaYLFSGPRGTGKTSAAKIFAKAVnclnppDGEpcnecEICKAitngslm 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLEL-----NSSDErgIDVIRTKVKnFARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSR 143
Cdd:PRK05563 89 DVIEIdaasnNGVDE--IRDIRDKVK-YAPSE----AKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 144 IIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-ITDEIVYKVS 222
Cdd:PRK05563 162 IPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGkVTYEDALEVT 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 223 SRARPTEIRQMMNLALEGKFNEARDLLYKLMiDWGMSG----EDvLVQMFR 269
Cdd:PRK05563 242 GSVSQEALDDLVDAIVEGDVAKALKILEELL-DEGKDPnrfiED-LIYYLR 290
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
19-159 |
7.04e-27 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 102.99 E-value: 7.04e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 19 GHEEIVKRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELFgeeNWRDNFLELNSSDERGIDVIRTKVKNFARTKPIG 98
Cdd:cd00009 2 GQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELF---RPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 99 D---APFKIIFLDESDALTSDAQNALRRTMEMYSDV------CRFILSCNYPS--RIIPPIQSRC-AIFRFSP 159
Cdd:cd00009 79 LaekAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPLlgDLDRALYDRLdIRIVIPL 151
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
7-277 |
9.32e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 107.24 E-value: 9.32e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 7 EKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAR-------------------ELFGEENW 66
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAKIFAKainclnpkdgdccnscsvcESINTNQS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 67 RDnFLELNSSDERGIDVIRTKVKNfartkpIGDAPF----KIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPS 142
Cdd:PRK05896 88 VD-IVELDAASNNGVDEIRNIIDN------INYLPTtfkyKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 143 RIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-ITDEIVYKV 221
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSeIDIEDINKT 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 222 SSRARPTEIRQMMNLALEGKFNEARDLLYKLMiDWGMSgedvLVQMFREIPNLDID 277
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELE-SKGIN----FEAFCRDLINLLID 291
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
8-218 |
2.97e-25 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 105.59 E-value: 2.97e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEE-------------------NWR 67
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALNCEQgltaepcnvcppcveitegRSV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 DNFlELNSSDERGIDVIRTKVKNfARTKPIGDApFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPP 147
Cdd:PRK14965 89 DVF-EIDGASNTGVDDIRELREN-VKYLPSRSR-YKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPIT 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 148 IQSRCAIFRFS--PLKKedIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEIV 218
Cdd:PRK14965 166 ILSRCQRFDFRriPLQK--IVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLdQVLAFCGDAVGDDDV 237
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
5-267 |
4.89e-25 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 105.28 E-value: 4.89e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 5 WVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE-------------ENWRDNF 70
Cdd:PRK07133 8 LYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVAKIFANALNCShktdllepcqeciENVNNSL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 71 --LELNSSDERGIDVIR---TKVKNFARtkpigDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRII 145
Cdd:PRK07133 88 diIEMDAASNNGVDEIReliENVKNLPT-----QSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 146 PPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-ITDEIVYKVSSR 224
Cdd:PRK07133 163 LTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNkITLKNVEELFGL 242
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1584888649 225 ARPTEIRQMMNLALEGKFNEARDLLYKLmIDWGMSGEDVLVQM 267
Cdd:PRK07133 243 VSNENLINLLNLLYSKDIKEVLNILNQI-KEQGIDPELLLISL 284
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
8-214 |
3.30e-24 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 102.58 E-value: 3.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAAL-------CLARELFGE------------ENWR 67
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHaYLFTGPRGVGKTSTARilakavnCTTNDPKGRpcgtcemcraiaEGSA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 DNFLELNSSDERGIDVIRtKVKNFARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPP 147
Cdd:PRK14950 89 VDVIEMDAASHTSVDDAR-EIIERVQFRP-ALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPAT 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 148 IQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNIT 214
Cdd:PRK14950 167 ILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLqQLATTYGGEIS 234
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
8-218 |
6.41e-24 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 101.65 E-value: 6.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE------------------ENWRD 68
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHaYLFSGLRGSGKTSSARIFARALVCEqgpsstpcdtciqcqsalENRHI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIR-----TKVK-NFARtkpigdapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPS 142
Cdd:PRK08451 87 DIIEMDAASNRGIDDIRelieqTKYKpSMAR--------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1584888649 143 RIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-ITDEIV 218
Cdd:PRK08451 159 KLPATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNaITESKV 235
|
|
| holB |
TIGR00678 |
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ... |
25-167 |
9.07e-24 |
|
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273213 [Multi-domain] Cd Length: 188 Bit Score: 95.77 E-value: 9.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 25 KRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDN----------FLELNSSDER---------GIDVI 84
Cdd:TIGR00678 2 QQLKRALEKGRLAHaYLFTGPEGVGKELLALALAKALLCEQRGGGEpcgechscrlIEAGNHPDLHrlepegqsiKVDQV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 85 RTKVKNFARTKPigDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKKED 164
Cdd:TIGR00678 82 RELVEFLSRTPQ--ESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEA 159
|
...
gi 1584888649 165 IAK 167
Cdd:TIGR00678 160 LLQ 162
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
8-253 |
1.30e-23 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 100.23 E-value: 1.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDN----------------- 69
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHaYLFSGIRGTGKTTLARIFAKALNCQNPTEDQepcnqcasckeissgts 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 70 --FLELNSSDERGIDVIR--TKVKNFARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRII 145
Cdd:PRK06305 90 ldVLEIDGASHRGIEDIRqiNETVLFTPSK----SRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 146 PPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVS-KNITDEIVYKVSSR 224
Cdd:PRK06305 166 GTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFpKSLDPDSVAKALGL 245
|
250 260
....*....|....*....|....*....
gi 1584888649 225 ARPTEIRQMMNLALEGKFNEARDLLYKLM 253
Cdd:PRK06305 246 LSQDSLYTLDEAITTQNYAQALEPVTDAM 274
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
8-220 |
4.50e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 98.43 E-value: 4.50e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAR------------------ELFGE-ENWR 67
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKavncqrmiddadylqevtEPCGEcESCR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 D-------NFLELNSSDERGIDVIRTKVKNfARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNY 140
Cdd:PRK14955 89 DfdagtslNISEFDAASNNSVDDIRLLREN-VRYGP-QKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 141 PSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQT--AASVSKNITDEIV 218
Cdd:PRK14955 167 LHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQviAFSVESEGEGSIR 246
|
..
gi 1584888649 219 YK 220
Cdd:PRK14955 247 YD 248
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
7-204 |
4.94e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 99.14 E-value: 4.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 7 EKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLA---------RELFGE--------ENWRD 68
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHaYLFSGPRGVGKTTTARLIAmavncsgedPKPCGEcesclavrRGAHP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRTkvknfARTKpIGDAPF----KIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRI 144
Cdd:PRK14963 86 DVLEIDAASNNSVEDVRD-----LREK-VLLAPLrggrKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKM 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 145 IPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQ 204
Cdd:PRK14963 160 PPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLE 219
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
8-269 |
6.12e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 97.57 E-value: 6.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPHL-LFSGPPGVGKTTAALCLARELFGEENWRDNFLE--LNSSD-ERG--I 81
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRkcIICKEiEKGlcL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 82 DVI------RTKVKNfarTKPIGD----AP----FKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPP 147
Cdd:PRK14961 89 DLIeidaasRTKVEE---MREILDniyySPsksrFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 148 IQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSK-NITDEIVYKVSSRAR 226
Cdd:PRK14961 166 ILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKgNINIKNVTDMLGLLN 245
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1584888649 227 PTEIRQMMNLALEgKFNEARDLLYKLMIDWGMSGEDVLVQMFR 269
Cdd:PRK14961 246 EKQSFLLTDALLK-KDSKKTMLLLNKISSIGIEWENILIEMLR 287
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
8-310 |
1.54e-22 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 98.20 E-value: 1.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDNFLELNSS-----DERGI 81
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHaYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATckavnEGRFI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 82 DVI------RTKVKNfarTKPIGD----AP----FKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPP 147
Cdd:PRK14960 88 DLIeidaasRTKVED---TRELLDnvpyAPtqgrFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPIT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 148 IQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAInvlqtaasvskNITDEIVYKVSSRARP 227
Cdd:PRK14960 165 VISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDAL-----------SLTDQAIAYGQGAVHH 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 228 TEIRQMMNLAlegkfneARDLLYKLMIDWGMSGEDVLVQM---FREiPNLD--------IDERKKVAVLEAIGECDFRIV 296
Cdd:PRK14960 234 QDVKEMLGLI-------DRTIIYDLILAVHQNQREKVSQLllqFRY-QALDvslvldqlISTLHELALLQYLPELGLKYS 305
|
330
....*....|....*
gi 1584888649 297 EGANERI-QLSALLA 310
Cdd:PRK14960 306 EEINAKIlQLSKLIS 320
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
8-234 |
3.14e-22 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 97.09 E-value: 3.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE-----------ENWRD------- 68
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIARILAKSLNCEnaqhgepcgvcQSCTQidagryv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRTKVKNfARTKPIGdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPI 148
Cdd:PRK08691 89 DLLEIDAASNTGIDNIREVLEN-AQYAPTA-GKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 149 QSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSknitdeivykvSSRARPT 228
Cdd:PRK08691 167 LSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALG-----------SGKVAEN 235
|
....*.
gi 1584888649 229 EIRQMM 234
Cdd:PRK08691 236 DVRQMI 241
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
8-216 |
4.30e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 96.36 E-value: 4.30e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE---------------ENWRDNF- 70
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHaYLFTGTRGVGKTTLARILAKSLNCEtgvtatpcgvcsaclEIDSGRFv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 71 --LELNSSDERGIDVIRTKVKN--FARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIP 146
Cdd:PRK14969 89 dlIEVDAASNTQVDAMRELLDNaqYAPTR----GRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPV 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 147 PIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDE 216
Cdd:PRK14969 165 TVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNE 234
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
8-213 |
6.84e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 95.62 E-value: 6.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAA----LCL-------------ARELFGEENWRD- 68
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCAriisLCLncsngptsdpcgtCHNCISIKNSNHp 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRTKVKNfARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPI 148
Cdd:PRK14964 86 DVIEIDAASNTSVDDIKVILEN-SCYLPI-SSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVTI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1584888649 149 QSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNI 213
Cdd:PRK14964 164 ISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNK 228
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
8-199 |
1.19e-21 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 95.41 E-value: 1.19e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSL-PHLLFSGPPGVGKTTAALCLARELfgeenwrdNFLelnSSDE-------- 78
Cdd:PRK14948 9 KYRPQRFDELVGQEAIATTLKNALISNRIaPAYLFTGPRGTGKTSSARILAKSL--------NCL---NSDKptpepcgk 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 79 ----RGI------DVIR------TKVKN---------FARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCR 133
Cdd:PRK14948 78 celcRAIaagnalDVIEidaasnTGVDNirelieraqFAPVQ----ARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1584888649 134 FILSCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDnkgLDAIIYV---SEGDLRKA 199
Cdd:PRK14948 154 FVLATTDPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIE---PEALTLVaqrSQGGLRDA 219
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
1-49 |
1.22e-21 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 95.29 E-value: 1.22e-21
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1584888649 1 MDVPWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPHLLFSGPPGVGK 49
Cdd:PRK04132 5 LEKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
3-244 |
1.72e-21 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 94.54 E-value: 1.72e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 3 VPWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL--------------------- 60
Cdd:PRK06645 9 IPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVncsalitenttiktceqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 61 --FGEENWRDnFLELNSSDERGIDVIRTKVKNfARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSC 138
Cdd:PRK06645 89 isFNNHNHPD-IIEIDAASKTSVDDIRRIIES-AEYKPL-QGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 139 NYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIv 218
Cdd:PRK06645 166 TEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKSDNII- 244
|
250 260
....*....|....*....|....*.
gi 1584888649 219 ykvssraRPTEIRQMMNLALEGKFNE 244
Cdd:PRK06645 245 -------SPQVINQMLGLVDSSVIIE 263
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
160-221 |
1.78e-21 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 86.04 E-value: 1.78e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1584888649 160 LKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIVYKV 221
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEV 62
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
15-237 |
1.35e-20 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 89.96 E-value: 1.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 15 DEITGHEEIVKRLKNYVKRKSL-PHLLFSGPPGVGKTTAALCLARELFGE----ENWRDNFLELN--------------- 74
Cdd:PRK07399 4 ANLIGQPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLSQgspsKNIRRRLEEGNhpdllwveptyqhqg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 75 ---SSDE--------RGIDVIRTK----VKNFARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEmysDVCR--FILS 137
Cdd:PRK07399 84 kliTASEaeeaglkrKAPPQIRLEqireIKRFLSRPPL-EAPRKVVVIEDAETMNEAAANALLKTLE---EPGNgtLILI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 138 CNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTaasvsknITDEI 217
Cdd:PRK07399 160 APSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPELLALAQGSPGAAIANIEQLQS-------IPPEL 232
|
250 260
....*....|....*....|
gi 1584888649 218 VYKVSSraRPTEIRQMMNLA 237
Cdd:PRK07399 233 LQKLEQ--PPKSPLEALELA 250
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
10-225 |
3.51e-20 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 90.12 E-value: 3.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 10 RPKRLDEITGHEEIV---KRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELfgeenwRDNFLELN--SSderGI--- 81
Cdd:COG2256 20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANAT------DAEFVALSavTS---GVkdi 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 82 -DVIRTKVKNFARTKPIgdapfkIIFLDESDALTSDAQNAL-----RRTmemysdvcrFIL----SCNyPSR-IIPPIQS 150
Cdd:COG2256 91 rEVIEEARERRAYGRRT------ILFVDEIHRFNKAQQDALlphveDGT---------ITLigatTEN-PSFeVNSALLS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 151 RCAIFRFSPLKKEDIAKKIKEICEKEG-------LTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSK-----NITDEIV 218
Cdd:COG2256 155 RCRVFVLKPLSEEDLEQLLERALADDErglggykLELDDEALEALARLADGDARRALNALELAVLSAPpdgviEITLELV 234
|
....*..
gi 1584888649 219 YKVSSRA 225
Cdd:COG2256 235 EEALQRR 241
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
8-203 |
6.29e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 90.39 E-value: 6.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAR------------------ELFGE-ENWR 67
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKavncqrmiddpvylqevtEPCGEcESCR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 68 D-------NFLELNSSDERGIDVIRTKVKNfARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNY 140
Cdd:PRK14954 89 DfdagtslNISEFDAASNNSVDDIRQLREN-VRYGP-QKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTE 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 141 PSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL 203
Cdd:PRK14954 167 LHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSIL 229
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
8-236 |
2.92e-19 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 88.21 E-value: 2.92e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEE-------NWRDNFLELNSSDer 79
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHaYLFTGTRGVGKTTLGRLLAKCLNCKTgvtaepcNKCENCVAINNNS-- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 80 GIDVI------RTKVKnfaRTKPIGD--------APFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRII 145
Cdd:PRK14957 87 FIDLIeidaasRTGVE---ETKEILDniqympsqGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 146 PPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVsknitdeivykVSSRA 225
Cdd:PRK14957 164 VTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISF-----------CGGEL 232
|
250
....*....|.
gi 1584888649 226 RPTEIRQMMNL 236
Cdd:PRK14957 233 KQAQIKQMLGI 243
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
19-160 |
8.80e-19 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 81.87 E-value: 8.80e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 19 GHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDN----------FLELNSSD---------E 78
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDLpcgqcrscrrIESGNHPDlviiepegqS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 79 RGIDVIRtKVKNFARTKPIGdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFS 158
Cdd:pfam13177 81 IKIDQIR-ELQKEFSKSPYE-GKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFK 158
|
..
gi 1584888649 159 PL 160
Cdd:pfam13177 159 PL 160
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
8-206 |
1.65e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 85.77 E-value: 1.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE------------------ENWRD 68
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHaYIFFGPRGVGKTTIARILAKRLNCEnpignepcnectscleitKGISS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRtKVKNFARTKPIGdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPI 148
Cdd:PRK14956 91 DVLEIDAASNRGIENIR-ELRDNVKFAPMG-GKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETI 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 149 QSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTA 206
Cdd:PRK14956 169 LSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQA 226
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
4-203 |
2.52e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 85.50 E-value: 2.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 4 PWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSL-PHLLFSGPPGVGKTTAALCLAREL------FGE-----ENWRD--- 68
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQETVKAILSRAAQENRVaPAYLFSGTRGVGKTTIARIFAKALncetapTGEpcntcEQCRKvtq 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 ----NFLELNSSDERGIDVIRtKVKnfartKPIGDAP----FKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNY 140
Cdd:PRK14959 85 gmhvDVVEIDGASNRGIDDAK-RLK-----EAIGYAPmegrYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 141 PSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL 203
Cdd:PRK14959 159 PHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLL 221
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
8-271 |
2.97e-18 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 85.21 E-value: 2.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDNFL-ELNS--SDERG--I 81
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANaYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCgECSSckSIDNDnsL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 82 DVIR------TKVKNFARTK-----PIGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQS 150
Cdd:PRK06647 89 DVIEidgasnTSVQDVRQIKeeimfPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 151 RCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEivykvssrarptE 229
Cdd:PRK06647 169 RCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFdQVVSFSDSDITLE------------Q 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1584888649 230 IRQMMNLA----LEGKF--------NEARDLLYKLMIDwGMSGEDVL---VQMFREI 271
Cdd:PRK06647 237 IRSKMGLTgdefLEKLAssilnedaKELLCVLDSVFLS-GVSVEQFLldcIEFFREL 292
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
16-194 |
1.53e-17 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 81.62 E-value: 1.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 16 EITGHEEIVKRLKNYVKRKSLPHL-LFSGPPGVGKTTAALCLARELFGEENWRD--NFLELNSSDER--GIDVIRTKVKN 90
Cdd:PRK05564 5 TIIGHENIKNRIKNSIIKNRFSHAhIIVGEDGIGKSLLAKEIALKILGKSQQREyvDIIEFKPINKKsiGVDDIRNIIEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 91 fARTKPI-GDApfKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKI 169
Cdd:PRK05564 85 -VNKKPYeGDK--KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEIEKFI 161
|
170 180
....*....|....*....|....*
gi 1584888649 170 KeiCEKEGLTIDNKglDAIIYVSEG 194
Cdd:PRK05564 162 S--YKYNDIKEEEK--KSAIAFSDG 182
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
39-160 |
5.87e-17 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 75.71 E-value: 5.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 39 LLFSGPPGVGKTTAALCLARELFGeenwrdNFLELNSSDERGIDVIRT--KVKN-FARTKPIgdAPfKIIFLDESDAL-- 113
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGA------PFIEISGSELVSKYVGESekRLRElFEAAKKL--AP-CVIFIDEIDALag 71
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1584888649 114 ---------TSDAQNALRRTMEMYSDVCR---FILSCNYPSRIIPPIQSRCAIFRFSPL 160
Cdd:pfam00004 72 srgsggdseSRRVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
8-206 |
8.20e-17 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 80.93 E-value: 8.20e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE-----------ENWRD------- 68
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHaYLFTGTRGVGKTTISRILAKCLNCEkgvsanpcndcENCREidegrfp 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRTKVKN--FARTKpigdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIP 146
Cdd:PRK14958 89 DLFEVDAASRTKVEDTRELLDNipYAPTK----GRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPV 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 147 PIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTA 206
Cdd:PRK14958 165 TVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQS 224
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
8-203 |
3.19e-16 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 79.15 E-value: 3.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEE--------------------NW 66
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHaYLFSGPRGCGKTSSARILARSLNCAQgptatpcgvcescvalapngPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 67 RDNFLELNSSDERGIDVIRtKVKNFARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIP 146
Cdd:PRK14952 86 SIDVVELDAASHGGVDDTR-ELRDRAFYAP-AQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLP 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1584888649 147 PIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL 203
Cdd:PRK14952 164 TIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVL 220
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
8-200 |
4.91e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 78.60 E-value: 4.91e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL--FGE--------------ENWRD-- 68
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHaYLFTGTRGVGKTTVSRILAKSLncQGPdgqggitatpcgvcQACRDid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 -----NFLELNSSDERGIDVIRTKVKNfARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSR 143
Cdd:PRK14951 89 sgrfvDYTELDAASNRGVDEVQQLLEQ-AVYKPV-QGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQK 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1584888649 144 IIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAI 200
Cdd:PRK14951 167 VPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDAL 223
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
11-246 |
1.36e-15 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 76.23 E-value: 1.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 11 PKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEEN-----------------WRD---- 68
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILSHPDpaeapetladpdpaspvWRQiaqg 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 ---NFLELNSS-DERG--------IDVIRTKVKNFARTKpiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFIL 136
Cdd:PRK09112 99 ahpNLLHITRPfDEKTgkfktaitVDEIRRVGHFLSQTS--GDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFIL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 137 SCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEIceKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAAS-VSKNITD 215
Cdd:PRK09112 177 ISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKALLLLNYGGLeIIATIDQ 254
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1584888649 216 ---------EIVYK----VSSRARPTEIRQMMNLALEGKFNEAR 246
Cdd:PRK09112 255 llagsgpdaRKAHKladaLSGRESEVQFDFFRDHLLDRIMAEAR 298
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
8-218 |
4.50e-15 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 75.68 E-value: 4.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL-----FGEENWRD------------- 68
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHaYLFTGTRGVGKTTLSRILAKSLnctgaDGEGGITAqpcgqcracteid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 -----NFLELNSSDERGIDVIrTKVKNFARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSR 143
Cdd:PRK12323 89 agrfvDYIEMDAASNRGVDEM-AQLLDKAVYAP-TAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQK 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 144 IIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEIV 218
Cdd:PRK12323 167 IPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTdQAIAYSAGNVSEEAV 242
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
8-218 |
7.02e-15 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 75.27 E-value: 7.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGE------------------ENWRD 68
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTLSRIFAKALNCEtgvtsqpcgvcracreidEGRFV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 69 NFLELNSSDERGIDVIRTKVKNfARTKPIgDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPI 148
Cdd:PRK07003 89 DYVEMDAASNRGVDEMAALLER-AVYAPV-DARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTV 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 149 QSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-ITDEIV 218
Cdd:PRK07003 167 LSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANeVTETAV 237
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
4-218 |
1.53e-14 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 74.32 E-value: 1.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 4 PWVEKYRPKRLDEITGHEEIV--KR-LKNYVKRKSLPHLLFSGPPGVGKTTAALCLARelfgeeNWRDNFLELNSSdERG 80
Cdd:PRK13341 17 PLADRLRPRTLEEFVGQDHILgeGRlLRRAIKADRVGSLILYGPPGVGKTTLARIIAN------HTRAHFSSLNAV-LAG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 81 IDVIRTKVKNFA--------RTkpigdapfkIIFLDESDALTSDAQNALRRTMEMySDVCRFILSCNYPS-RIIPPIQSR 151
Cdd:PRK13341 90 VKDLRAEVDRAKerlerhgkRT---------ILFIDEVHRFNKAQQDALLPWVEN-GTITLIGATTENPYfEVNKALVSR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 152 CAIFRFSPLKKED---IAKKIKEICE----KEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIV 218
Cdd:PRK13341 160 SRLFRLKSLSDEDlhqLLKRALQDKErgygDRKVDLEPEAEKHLVDVANGDARSLLNALELAVESTPPDEDGLI 233
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
4-210 |
1.38e-13 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 71.14 E-value: 1.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 4 PWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-----LLFSGPPGVGKTTAALCLARELFGE--ENWRDNFLELNSS 76
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKELGIQvqEWSNPTLPDFQKN 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 77 DERGIDVIRTKVKNF-------------ARTKP--IGD---APFKIIFLDESDALTSDAQNALRRTME-MYSDVCRF--- 134
Cdd:TIGR00602 153 DHKVTLSLESCFSNFqsqievfsefllrATNKLqmLGDdlmTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGRCplv 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 135 --ILSC-----NYPSRIIPP-------IQSRCAIFR--FSPLKKEDIAKKIKEICEKEG-------LTIDNKGLDAIIYV 191
Cdd:TIGR00602 233 fiITESlegdnNQRRLLFPAetimnkeILEEPRVSNisFNPIAPTIMKKFLNRIVTIEAkkngekiKVPKKTSVELLCQG 312
|
250
....*....|....*....
gi 1584888649 192 SEGDLRKAINVLQTAASVS 210
Cdd:TIGR00602 313 CSGDIRSAINSLQFSSSKS 331
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
10-60 |
1.18e-12 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 67.41 E-value: 1.18e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 10 RPKRLDEITGHEEIVKRLKNYV----KRK-SLPHLLFSGPPGVGKTTAALCLAREL 60
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIeaakKRGeALDHVLLYGPPGLGKTTLAHIIANEM 78
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
10-60 |
2.77e-12 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 66.31 E-value: 2.77e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 10 RPKRLDEITGHEEIVKRLKNYVK-----RKSLPHLLFSGPPGVGKTTAALCLAREL 60
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTTLANIIANEM 75
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
160-220 |
3.36e-12 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 60.95 E-value: 3.36e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 160 LKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN--ITDEIVYK 220
Cdd:cd18133 1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDgkISLDRVYQ 63
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
10-60 |
5.50e-12 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 62.90 E-value: 5.50e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 10 RPKRLDEITGHEEIVKRLKNYVK-----RKSLPHLLFSGPPGVGKTTAALCLAREL 60
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEaakqrGEALDHVLLYGPPGLGKTTLANIIANEM 57
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
60-253 |
1.35e-10 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 61.04 E-value: 1.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 60 LFGEENWR-----DNFLELNSSDERGIDVIR--------TKVKNFARTKPIGdAPFKIIFLDESDALT--SDAQNALRRT 124
Cdd:COG1466 9 LYGEEPLLideaaDALRAAALAEDDGFNRTRldgaetdwAELLDEAQTLSLF-GERRLVIVRNAEFLKkpGEGLEALEAY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 125 MEMYSDVCRFILSCNYP---SRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAIN 201
Cdd:COG1466 88 LANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGDLLALAQ 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1584888649 202 VLQ---TAASVSKNITDEIVYKVSSRARPTEIRQMMNLALEGKFNEARDLLYKLM 253
Cdd:COG1466 168 ELEklaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLL 222
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
3-216 |
7.44e-10 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 59.54 E-value: 7.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 3 VPWVEKYRPKRLDEITGHEEIVKRLKNYV----------KRKSLP---HLLFSGPPGVGKTTAALCLARElfgeenWRDN 69
Cdd:COG0464 145 EEELLELREAILDDLGGLEEVKEELRELValplkrpelrEEYGLPpprGLLLYGPPGTGKTLLARALAGE------LGLP 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 70 FLELNSSD---------ERGI-DVIRTkvknfARtkpiGDAPFkIIFLDESDALTSDAQNALRRTM------------EM 127
Cdd:COG0464 219 LIEVDLSDlvskyvgetEKNLrEVFDK-----AR----GLAPC-VLFIDEADALAGKRGEVGDGVGrrvvntlltemeEL 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 128 YSDVCrFILSCNYPSRIIPPIQSRCA-IFRFSPLKKEDIAKKIKEICEKEGLTiDNKGLDAIIYVSEG----DLRKAIN- 201
Cdd:COG0464 289 RSDVV-VIAATNRPDLLDPALLRRFDeIIFFPLPDAEERLEIFRIHLRKRPLD-EDVDLEELAEATEGlsgaDIRNVVRr 366
|
250
....*....|....*.
gi 1584888649 202 -VLQTAASVSKNITDE 216
Cdd:COG0464 367 aALQALRLGREPVTTE 382
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
10-203 |
7.69e-10 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 59.27 E-value: 7.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 10 RPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDNF-------LELNSSD---- 77
Cdd:PRK07471 14 HPRETTALFGHAAAEAALLDAYRSGRLHHaWLIGGPQGIGKATLAYRMARFLLATPPPGGDGavppptsLAIDPDHpvar 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 78 -------------ERGID----VIRT--------KVKNFARTKPiGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVC 132
Cdd:PRK07471 94 riaagahgglltlERSWNekgkRLRTvitvdevrELISFFGLTA-AEGGWRVVIVDTADEMNANAANALLKVLEEPPARS 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 133 RFILSCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIkeicEKEGLTIDNKGLDAIIYVSEGDLRKAINVL 203
Cdd:PRK07471 173 LFLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDAL----AAAGPDLPDDPRAALAALAEGSVGRALRLA 239
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
8-253 |
2.34e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 58.37 E-value: 2.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELfgeenwrdNF----------LELNSS 76
Cdd:PRK09111 17 KYRPQTFDDLIGQEAMVRTLTNAFETGRIAQaFMLTGVRGVGKTTTARILARAL--------NYegpdgdggptIDLCGV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 77 DE--------RGIDVI------RTKVKNF------ARTKPIGdAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFIL 136
Cdd:PRK09111 89 GEhcqaimegRHVDVLemdaasHTGVDDIreiiesVRYRPVS-ARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIF 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 137 SCNyPSRIIP-PIQSRCAIF---RFSPlkkEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSK 211
Cdd:PRK09111 168 ATT-EIRKVPvTVLSRCQRFdlrRIEA---DVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLdQAIAHGAG 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1584888649 212 NITDEIVykvssrarpteiRQMMNLAlegkfNEAR--DLLYKLM 253
Cdd:PRK09111 244 EVTAEAV------------RDMLGLA-----DRARviDLFEALM 270
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
33-164 |
6.81e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 56.25 E-value: 6.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 33 RKSLPH-LLFSGPPGVGKTTAALCLARELFGEE-------------------NWRDNF-LELNSSDER-GIDVIRTKVKN 90
Cdd:PRK05707 18 RGRHPHaYLLHGPAGIGKRALAERLAAALLCEApqgggacgsckgcqllragSHPDNFvLEPEEADKTiKVDQVRELVSF 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 91 FARTKPIGDapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKKED 164
Cdd:PRK05707 98 VVQTAQLGG--RKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEE 169
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
4-60 |
1.92e-08 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 53.42 E-value: 1.92e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1584888649 4 PWVEKYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-----LLFSGPPGVGKTTAALCLAREL 60
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL 69
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
38-157 |
5.01e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 51.22 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 38 HLLFSGPPGVGKTTAALCLARELFGEENwrdNFLELNSSDERGIDVIRTKVKNFARTKPIGD--------------APFK 103
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGG---GVIYIDGEDILEEVLDQLLLIIVGGKKASGSgelrlrlalalarkLKPD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1584888649 104 IIFLDESDALTSDAQNALRRTMEMYSDV--------CRFILSCNYPSRIIPPIQSRCAIFRF 157
Cdd:smart00382 81 VLILDEITSLLDAEQEALLLLLEELRLLlllkseknLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
160-221 |
5.37e-08 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 49.04 E-value: 5.37e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 160 LKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEIVYKV 221
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLdQAIAFGGGRVTLDDVREM 63
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
14-152 |
2.52e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 50.65 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 14 LDEITGHEEIVKRLKN---YVKRKSLP---------HLLFSGPPGVGKTTAALCLARELfgeenwRDNFLELNSSdergi 81
Cdd:COG1223 1 LDDVVGQEEAKKKLKLiikELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGEL------KLPLLTVRLD----- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 82 DVIRTKV----KN------FARTKPIgdapfkIIFLDESDALT---SDAQ---------NALRRTMEMYSDVCRFILSCN 139
Cdd:COG1223 70 SLIGSYLgetaRNlrklfdFARRAPC------VIFFDEFDAIAkdrGDQNdvgevkrvvNALLQELDGLPSGSVVIAATN 143
|
170
....*....|...
gi 1584888649 140 YPSRIIPPIQSRC 152
Cdd:COG1223 144 HPELLDSALWRRF 156
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
12-60 |
4.94e-07 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 50.38 E-value: 4.94e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 12 KRLDEITGHEEIVKRLKNYVK----RK-SLPHLLFSGPPGVGKTTAALCLAREL 60
Cdd:TIGR00635 1 KLLAEFIGQEKVKEQLQLFIEaakmRQeALDHLLLYGPPGLGKTTLAHIIANEM 54
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
39-151 |
7.18e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 48.05 E-value: 7.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 39 LLFSGPPGVGKTTAALCLARELfgeenwRDNFLELNSSD--ERGIDVIRTKVKN-FARTKpigDAPFKIIFLDESDALTS 115
Cdd:cd19481 29 ILLYGPPGTGKTLLAKALAGEL------GLPLIVVKLSSllSKYVGESEKNLRKiFERAR---RLAPCILFIDEIDAIGR 99
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 116 D------------AQNALRRTMEMY---SDVCrFILSCNYPSRIIPPIQSR 151
Cdd:cd19481 100 KrdssgesgelrrVLNQLLTELDGVnsrSKVL-VIAATNRPDLLDPALLRP 149
|
|
| PTZ00112 |
PTZ00112 |
origin recognition complex 1 protein; Provisional |
1-206 |
1.00e-06 |
|
origin recognition complex 1 protein; Provisional
Pssm-ID: 240274 [Multi-domain] Cd Length: 1164 Bit Score: 50.37 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 1 MDVPWVEKYRPKRLDEItghEEIVKRLKNYVKRKSLPHLLF-SGPPGVGKTTAALCLARELfgEENWRDNFL-ELNSSDE 78
Cdd:PTZ00112 748 MQLDVVPKYLPCREKEI---KEVHGFLESGIKQSGSNQILYiSGMPGTGKTATVYSVIQLL--QHKTKQKLLpSFNVFEI 822
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 79 RGIDVIRTKV-------KNFARTKPIGDAPFKII-----------------FLDESDALTSDAQNALRRTMEMYSDV-CR 133
Cdd:PTZ00112 823 NGMNVVHPNAayqvlykQLFNKKPPNALNSFKILdrlfnqnkkdnrnvsilIIDEIDYLITKTQKVLFTLFDWPTKInSK 902
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 134 FIL-----SCNYPSRIIPPIQSRCAIFR--FSPLKKEDIAKKIKEICEKEGLTIDNKGLD----AIIYVSeGDLRKAINV 202
Cdd:PTZ00112 903 LVLiaisnTMDLPERLIPRCRSRLAFGRlvFSPYKGDEIEKIIKERLENCKEIIDHTAIQlcarKVANVS-GDIRKALQI 981
|
....
gi 1584888649 203 LQTA 206
Cdd:PTZ00112 982 CRKA 985
|
|
| holA |
TIGR01128 |
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ... |
154-264 |
1.24e-06 |
|
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273455 [Multi-domain] Cd Length: 302 Bit Score: 49.18 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 154 IFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLR---KAINVLQTAASvSKNITDEIVYKVSSRARPTEI 230
Cdd:TIGR01128 105 IVECKTPKEQELPRWIQARLKKLGLRIDPDAVQLLAELVEGNLLaiaQELEKLALYAP-DGKITLEDVEEAVSDSARFNV 183
|
90 100 110
....*....|....*....|....*....|....
gi 1584888649 231 RQMMNLALEGKFNEARDLLYKLMidwgMSGEDVL 264
Cdd:TIGR01128 184 FDLTDALLEGKAARALRILKGLL----GEGEEPL 213
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
102-159 |
1.88e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 48.65 E-value: 1.88e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 102 FKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSP 159
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTP 166
|
|
| PRK08699 |
PRK08699 |
DNA polymerase III subunit delta'; Validated |
33-171 |
3.67e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181538 [Multi-domain] Cd Length: 325 Bit Score: 47.94 E-value: 3.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 33 RKSLPH-LLFSGPPGVGKTTAALCLARELFGEENWRDN-------------------FLELNS-SDER---------GID 82
Cdd:PRK08699 17 WERRPNaWLFAGKKGIGKTAFARFAAQALLCETPAPGHkpcgecmschlfgqgshpdFYEITPlSDEPengrkllqiKID 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 83 VIRTKVKNFARTKPIGDapFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKK 162
Cdd:PRK08699 97 AVREIIDNVYLTSVRGG--LRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAPSH 174
|
....*....
gi 1584888649 163 EDIAKKIKE 171
Cdd:PRK08699 175 EEALAYLRE 183
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
160-218 |
3.92e-06 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 44.16 E-value: 3.92e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 160 LKKEDI------AKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQTAASVSKN-----ITDEIV 218
Cdd:cd18139 1 LSEEDLekllkrALEDKERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAEEdggivITLEDL 70
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
8-218 |
4.32e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 48.32 E-value: 4.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLARELfgeeNWR-----------DNFLELns 75
Cdd:PRK07994 9 KWRPQTFAEVVGQEHVLTALANALDLGRLHHaYLFSGTRGVGKTTIARLLAKGL----NCEtgitatpcgecDNCREI-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 76 sDE-RGIDVI------RTKVKNfarTKPIGD----AP----FKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNY 140
Cdd:PRK07994 83 -EQgRFVDLIeidaasRTKVED---TRELLDnvqyAPargrFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTD 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1584888649 141 PSRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVL-QTAASVSKNITDEIV 218
Cdd:PRK07994 159 PQKLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTdQAIASGNGQVTTDDV 237
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
10-167 |
7.75e-06 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 47.49 E-value: 7.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 10 RPKRLDEITGHEEIVKRLKNYVKRKSL----PHLLFSGPPGVGKTTAALCLARELFGEENWRDN----FLELNS--SDER 79
Cdd:COG5635 150 LLVSLDDLYVPLNLLERIESLKRLELLeakkKRLLILGEPGSGKTTLLRYLALELAERYLDAEDpipiLIELRDlaEEAS 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 80 GIDVIRtkvKNFARTKPIGDAPFK---------IIF--LDE--SDALTSDAQNALRRTMEMYSDvCRFILSC---NYPSR 143
Cdd:COG5635 230 LEDLLA---EALEKRGGEPEDALErllrngrllLLLdgLDEvpDEADRDEVLNQLRRFLERYPK-ARVIITSrpeGYDSS 305
|
170 180
....*....|....*....|....
gi 1584888649 144 IIppiqSRCAIFRFSPLKKEDIAK 167
Cdd:COG5635 306 EL----EGFEVLELAPLSDEQIEE 325
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
55-166 |
7.86e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 46.65 E-value: 7.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 55 CLARELFGEENWRDnFLELNSSDER--GIDVIR---TKVKNFARTKpiGDapfKIIFLDESDALTSDAQNALRRTMEMYS 129
Cdd:PRK06871 62 CHSCHLFQAGNHPD-FHILEPIDNKdiGVDQVReinEKVSQHAQQG--GN---KVVYIQGAERLTEAAANALLKTLEEPR 135
|
90 100 110
....*....|....*....|....*....|....*..
gi 1584888649 130 DVCRFILSCNYPSRIIPPIQSRCAIFRFSPlKKEDIA 166
Cdd:PRK06871 136 PNTYFLLQADLSAALLPTIYSRCQTWLIHP-PEEQQA 171
|
|
| PRK08769 |
PRK08769 |
DNA polymerase III subunit delta'; Validated |
39-178 |
8.74e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181551 [Multi-domain] Cd Length: 319 Bit Score: 46.49 E-value: 8.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 39 LLFSGPPGVGKTTAALCLA----------------RELFGEENWRD----NFLELNSSD----ERGIDVIRTKVKNFART 94
Cdd:PRK08769 29 LLICGPEGLGKRAVALALAehvlasgpdpaaaqrtRQLIAAGTHPDlqlvSFIPNRTGDklrtEIVIEQVREISQKLALT 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 95 KPIGDApfKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFS-PLKKEDIA----KKI 169
Cdd:PRK08769 109 PQYGIA--QVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKlPPAHEALAwllaQGV 186
|
....*....
gi 1584888649 170 KEICEKEGL 178
Cdd:PRK08769 187 SERAAQEAL 195
|
|
| PRK07132 |
PRK07132 |
DNA polymerase III subunit delta'; Validated |
95-171 |
2.18e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180855 [Multi-domain] Cd Length: 299 Bit Score: 45.48 E-value: 2.18e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1584888649 95 KPIGDAPFKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRCAIFRFSPLKKEDIAKKIKE 171
Cdd:PRK07132 84 SSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKLLS 160
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
12-126 |
4.73e-05 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 43.32 E-value: 4.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 12 KRLDE-ITGHEEIVKRLKNYVKR---------KSLPHLLFSGPPGVGKTTAALCLARELFGEEnwrDNFLELN-SSDERG 80
Cdd:cd19499 7 ERLHErVVGQDEAVKAVSDAIRRaraglsdpnRPIGSFLFLGPTGVGKTELAKALAELLFGDE---DNLIRIDmSEYMEK 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1584888649 81 IDVIRTK------VKNFAR---TKPIGDAPFKIIFLDESDALTSDAQNALRRTME 126
Cdd:cd19499 84 HSVSRLIgappgyVGYTEGgqlTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLD 138
|
|
| PRK07993 |
PRK07993 |
DNA polymerase III subunit delta'; Validated |
80-152 |
6.84e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181190 [Multi-domain] Cd Length: 334 Bit Score: 43.90 E-value: 6.84e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1584888649 80 GIDVIRT---KVKNFARtkpIGDApfKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILSCNYPSRIIPPIQSRC 152
Cdd:PRK07993 89 GVDAVREvteKLYEHAR---LGGA--KVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRC 159
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
9-262 |
9.57e-05 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 43.68 E-value: 9.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 9 YRPKRL----DEItghEEIVKRLKNYVKRKSLPHLLFSGPPGVGKTTAALCLARELFGEENWRDNFL------------- 71
Cdd:COG1474 23 YVPDRLphreEEI---EELASALRPALRGERPSNVLIYGPTGTGKTAVAKYVLEELEEEAEERGVDVrvvyvncrqastr 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 72 ---------ELNSSDE---RGI--DVIRTKVKNFARTKpigDAPFkIIFLDESDALTSDAQN----ALRRTMEMYSDV-C 132
Cdd:COG1474 100 yrvlsrileELGSGEDipsTGLstDELFDRLYEALDER---DGVL-VVVLDEIDYLVDDEGDdllyQLLRANEELEGArV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 133 RFILSCN---YPSRIIPPIQSR--CAIFRFSPLKKEDiakkIKEICE---KEGL---TIDNkglDAIIYVSE------GD 195
Cdd:COG1474 176 GVIGISNdleFLENLDPRVKSSlgEEEIVFPPYDADE----LRDILEdraELAFydgVLSD---EVIPLIAAlaaqehGD 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1584888649 196 LRKAINVLQTAASV-----SKNITDEIVYKVSSRARPTEIRQMMN-LALEGKfneardLLYKLMIDWGMSGED 262
Cdd:COG1474 249 ARKAIDLLRVAGEIaeregSDRVTEEHVREAREKIERDRLLEVLRgLPTHEK------LVLLAIAELLKDGED 315
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
14-115 |
1.79e-04 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 42.91 E-value: 1.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 14 LDEITGHEEI---VKRLKNYVK------RKSLP------HLLFSGPPGVGKTTAALCLARELFG-----EENWRdnflEL 73
Cdd:TIGR03922 275 LAEQIGLERVkrqVAALKSSTAmalaraERGLPvaqtsnHMLFAGPPGTGKTTIARVVAKIYCGlgvlrKPLVR----EV 350
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1584888649 74 NSSDERGIDVIRTKVKNfarTKPIGDAPFKIIFLDESDALTS 115
Cdd:TIGR03922 351 SRADLIGQYIGESEAKT---NEIIDSALGGVLFLDEAYTLVE 389
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
40-121 |
1.83e-04 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 41.41 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 40 LFSGPPGVGKTTAALCLARELFGEEnwrDNFLELNSS---------------------DERGIdvirtkvknfaRTKPIG 98
Cdd:pfam07724 7 LFLGPTGVGKTELAKALAELLFGDE---RALIRIDMSeymeehsvsrligappgyvgyEEGGQ-----------LTEAVR 72
|
90 100
....*....|....*....|...
gi 1584888649 99 DAPFKIIFLDESDALTSDAQNAL 121
Cdd:pfam07724 73 RKPYSIVLIDEIEKAHPGVQNDL 95
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
20-137 |
3.70e-04 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 40.34 E-value: 3.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 20 HEEIVKRLknyvkRKSLPH-LLFSGPPGVGKTTAALCLARELfgeenwRDNFL-----ELNS----SDERGIDVIrtkvk 89
Cdd:cd19511 15 HPDAFKRL-----GIRPPKgVLLYGPPGCGKTLLAKALASEA------GLNFIsvkgpELFSkyvgESERAVREI----- 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1584888649 90 nFARTKpigDAPFKIIFLDESDALTSdaqnalRRTMEMYSDVCRFILS 137
Cdd:cd19511 79 -FQKAR---QAAPCIIFFDEIDSLAP------RRGQSDSSGVTDRVVS 116
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
19-66 |
5.11e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 40.18 E-value: 5.11e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 19 GHEEIVKRLKNYVKR---KSLPHLLFSGPPGVGKTTAALCLARELFGEENW 66
Cdd:pfam13191 4 GREEELEQLLDALDRvrsGRPPSVLLTGEAGTGKTTLLRELLRALERDGGY 54
|
|
| DNA_pol3_delta |
pfam06144 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
67-204 |
5.73e-04 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 428788 [Multi-domain] Cd Length: 174 Bit Score: 39.96 E-value: 5.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 67 RDNFLELNSSDERGIDVIRTKVKNFARTKPIGdAPFKII------FLDESDALTSDAQNALRRTMEMYSDVCRFILSCNY 140
Cdd:pfam06144 24 KQGFEDFNYISFDLNEDWIDDALEECETLPFF-SDKRIVvlnnpnLLEKESKLNEHLLKRLEEYLSNPPPDSLLILFAPG 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1584888649 141 P----SRIIPPIQSRCAIFRFSPLKKEDIAKKIKEICEKEGLTIDNKGLDAIIYVSEGDLRKAINVLQ 204
Cdd:pfam06144 103 KlderKKLTKLLKKKATVVECFTLKEEELIQWIQSRAQELGLQIEPEAIELLCELVENNLSALAQELE 170
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
40-218 |
6.88e-04 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 40.71 E-value: 6.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 40 LFSGPPGVGKTTAA-----------------LCLARELFGEEnwrdnFLELNSSDERG-----IDVIRTKVKNFARTkpi 97
Cdd:COG2842 54 VVYGESGVGKTTAAreyanrnpnviyvtaspSWTSKELLEEL-----AEELGIPAPPGtiadlRDRILERLAGTGRL--- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 98 gdapfkiIFLDESDALTSDAQNALRRTMEmYSDvCRFILSCN--YPSRI--IPPIQSRCA-IFRFSPLKKEDIAKKIKEI 172
Cdd:COG2842 126 -------LIIDEADHLKPKALEELRDIHD-ETG-VGVVLIGMerLPAKLkrYEQLYSRIGfWVEFKPLSLEDVRALAEAW 196
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1584888649 173 CEKEgltiDNKGLDAIIYVSEGDLRKAINVLQTAASVSKNITDEIV 218
Cdd:COG2842 197 GELT----DPDLLELLHRITRGNLRRLDRTLRLAARAAKRNGLTKI 238
|
|
| PRK09270 |
PRK09270 |
nucleoside triphosphate hydrolase domain-containing protein; Reviewed |
8-60 |
9.26e-04 |
|
nucleoside triphosphate hydrolase domain-containing protein; Reviewed
Pssm-ID: 236442 Cd Length: 229 Bit Score: 39.92 E-value: 9.26e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 8 KYRPKRLDEItgHEEIVKRLKNYVKRKSLPHLLF-SGPPGVGKTTAALCLAREL 60
Cdd:PRK09270 6 QYRDEEIEAV--HKPLLRRLAALQAEPQRRTIVGiAGPPGAGKSTLAEFLEALL 57
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
38-60 |
1.04e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 40.15 E-value: 1.04e-03
|
| AAA_18 |
pfam13238 |
AAA domain; |
40-113 |
1.25e-03 |
|
AAA domain;
Pssm-ID: 433052 [Multi-domain] Cd Length: 128 Bit Score: 38.18 E-value: 1.25e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 40 LFSGPPGVGKTTAALCLARELFGEENWRDNFLELNSSDERGIDVIRTKVKNFARTKPIGDAPFKIIFLDESDAL 113
Cdd:pfam13238 2 LITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKRLDEDKLDRLLDLLEENAALEEGGNL 75
|
|
| PRK06835 |
PRK06835 |
DNA replication protein DnaC; Validated |
21-60 |
1.52e-03 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 235871 [Multi-domain] Cd Length: 329 Bit Score: 39.88 E-value: 1.52e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1584888649 21 EEIVKRLKNYVKRKSLPH--LLFSGPPGVGKTTAALCLAREL 60
Cdd:PRK06835 166 EKILEKCKNFIENFDKNNenLLFYGNTGTGKTFLSNCIAKEL 207
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
38-152 |
1.68e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 38.04 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 38 HLLFSGPPGVGKTTAALCLARELFGEENW---------RDNFLELNSSDERGIDVIRTKVKNFARTKpigdapfKIIFLD 108
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFyvqltrdttEEDLFGRRNIDPGGASWVDGPLVRAAREG-------EIAVLD 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1584888649 109 ESDALTSDAQNAL------RRTMEMYS--------DVCRFILSCNYPSR----IIPPIQSRC 152
Cdd:pfam07728 74 EINRANPDVLNSLlslldeRRLLLPDGgelvkaapDGFRLIATMNPLDRglneLSPALRSRF 135
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
21-65 |
1.71e-03 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 39.75 E-value: 1.71e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1584888649 21 EEIVKRLKNYVKRKslPHLLFSGPPGVGKTTAALCLARELFGEEN 65
Cdd:COG1401 208 EETLEAFLAALKTK--KNVILAGPPGTGKTYLARRLAEALGGEDN 250
|
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
39-137 |
2.31e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 37.57 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 39 LLFSGPPGVGKTTaalcLARELFGEENWRDNFLELNSSDERGIDVIRTKVKNFARTKPIGDAPFkiIFLDESDALTsDAQ 118
Cdd:pfam13173 5 LVITGPRQVGKTT----LLLQLIKELLPPENILYINLDDPRLLKLADFELLELFLELLYPGKTY--LFLDEIQRVP-DWE 77
|
90
....*....|....*....
gi 1584888649 119 NALRRTMEMYSDvCRFILS 137
Cdd:pfam13173 78 LALKRLYDDGPN-GRVILT 95
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
8-60 |
2.48e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.58 E-value: 2.48e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1584888649 8 KYRPKRLDEITGHEEIVKRLKNYVKRKSLPH-LLFSGPPGVGKTTAALCLAREL 60
Cdd:PRK07764 8 RYRPATFAEVIGQEHVTEPLSTALDSGRINHaYLFSGPRGCGKTSSARILARSL 61
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
2-125 |
3.18e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 38.83 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 2 DVPWVEKYRPKRLDEITGHEEIVKRLKNYVKR------------KSLPH-LLFSGPPGVGKTTAALCLARELfgeenwRD 68
Cdd:COG1222 65 GTAVPAESPDVTFDDIGGLDEQIEEIREAVELplknpelfrkygIEPPKgVLLYGPPGTGKTLLAKAVAGEL------GA 138
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1584888649 69 NFLELNSSD---------ERGIDvirtKVKNFARTKpigdAPfKIIFLDESDALTSDAQNA-----LRRTM 125
Cdd:COG1222 139 PFIRVRGSElvskyigegARNVR----EVFELAREK----AP-SIIFIDEIDAIAARRTDDgtsgeVQRTV 200
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
38-137 |
3.54e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 36.94 E-value: 3.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 38 HLLFSGPPGVGKTTAALCLAR------------ELFGEENWRD------NFLELNSSDERGIDVIRTKVKNFARTKPIGd 99
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEqlpevrdsvvfvDLPSGTSPKDllrallRALGLPLSGRLSKEELLAALQQLLLALAVA- 85
|
90 100 110
....*....|....*....|....*....|....*...
gi 1584888649 100 apfKIIFLDESDALTSDAQNALRRTMEMYSDVCRFILS 137
Cdd:pfam13401 86 ---VVLIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
39-116 |
3.84e-03 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 37.27 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1584888649 39 LLFSGPPGVGKTTAALCLARELfgeenwRDNFLELNSSD---------ERGIDVIRTKVKNFARTkpigdapfkIIFLDE 109
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEA------GANFLSISGPSivskylgesEKNLREIFEEARSHAPS---------IIFIDE 101
|
....*..
gi 1584888649 110 SDALTSD 116
Cdd:cd19503 102 IDALAPK 108
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
40-65 |
8.31e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 37.75 E-value: 8.31e-03
10 20
....*....|....*....|....*.
gi 1584888649 40 LFSGPPGVGKTTAALCLARELFGEEN 65
Cdd:COG0542 583 LFLGPTGVGKTELAKALAEFLFGDED 608
|
|
| |
